Receptor for advanced glycation end products--soluble form and gene polymorphisms in chronic haemodialysis patients

Name: Work Video:
Duration: 3 min 30 s
Description: Background. The receptor for advanced glycation end products (RAGE) is involved in the pathogenesis of vascular and inflammatory diseases. The pathological effects mediated via RAGE are physiologically inhibited by soluble RAGE (sRAGE). Our aim was to study sRAGE and RAGE gene polymorphisms in haemodialysis (HD) patients.
Marta Kalousová; Marie Jáchymová; Oto Mestek; Magdaléna Hodková; Markéta Kazderová; Vladimı́r Tesař; Tomáš Zima
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Kalousova', 'raw_affiliation_strings': ['Institute of Clinical Chemistry and Laboratory Diagnostics, Department of Nephrology, 1st Faculty of Medicine and General University Hospital, Charles University, Karlovo nám. 32, 121 11 Prague 2, Czech Republic. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'Institute of Clinical Chemistry and Laboratory Diagnostics, Department of Nephrology, 1st Faculty of Medicine and General University Hospital, Charles University, Karlovo nám. 32, 121 11 Prague 2, Czech Republic. [email protected]', 'institution_ids': ['https://openalex.org/I21250087']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083780930', 'display_name': 'Marie Jáchymová', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I21250087', 'display_name': 'Charles University', 'ror': 'https://ror.org/024d6js02', 'country_code': 'CZ', 'type': 'education', 'lineage': ['https://openalex.org/I21250087']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'M. Jachymova', 'raw_affiliation_strings': ['Charles University, Prague, Czechia'], 'affiliations': [{'raw_affiliation_string': 'Charles University, Prague, Czechia', 'institution_ids': ['https://openalex.org/I21250087']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014599348', 'display_name': 'Oto Mestek', 'orcid': 'https://orcid.org/0000-0002-2190-5517'}, 'institutions': [{'id': 'https://openalex.org/I21250087', 'display_name': 'Charles University', 'ror': 'https://ror.org/024d6js02', 'country_code': 'CZ', 'type': 'education', 'lineage': ['https://openalex.org/I21250087']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'O. 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Hodkova', 'raw_affiliation_strings': ['Charles University, Prague, Czechia'], 'affiliations': [{'raw_affiliation_string': 'Charles University, Prague, Czechia', 'institution_ids': ['https://openalex.org/I21250087']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076454680', 'display_name': 'Markéta Kazderová', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I21250087', 'display_name': 'Charles University', 'ror': 'https://ror.org/024d6js02', 'country_code': 'CZ', 'type': 'education', 'lineage': ['https://openalex.org/I21250087']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'M. Kazderova', 'raw_affiliation_strings': ['Charles University, Prague, Czechia'], 'affiliations': [{'raw_affiliation_string': 'Charles University, Prague, Czechia', 'institution_ids': ['https://openalex.org/I21250087']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081888215', 'display_name': 'Vladimı́r Tesař', 'orcid': 'https://orcid.org/0000-0001-6982-0689'}, 'institutions': [{'id': 'https://openalex.org/I21250087', 'display_name': 'Charles University', 'ror': 'https://ror.org/024d6js02', 'country_code': 'CZ', 'type': 'education', 'lineage': ['https://openalex.org/I21250087']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'V. 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Zima', 'raw_affiliation_strings': ['Charles University, Prague, Czechia'], 'affiliations': [{'raw_affiliation_string': 'Charles University, Prague, Czechia', 'institution_ids': ['https://openalex.org/I21250087']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3182, 'currency': 'EUR', 'value_usd': 3431, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.367, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 79, 'citation_normalized_percentile': {'value': 0.865724, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '22', 'issue': '7', 'first_page': '2020', 'last_page': '2026'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11142', 'display_name': 'Advanced Glycation End Products research', 'score': 1.0, 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