Aberrant regulation of FBW7 in cancer

Name: Work Video:
Duration: 3 min 30 s
Lixia Wang; Xiantao Ye; Yueyong Liu; Wenyi Wei; Zhiwei Wang
{'id': 'https://openalex.org/W2132251735', 'doi': 'https://doi.org/10.18632/oncotarget.1859', 'title': 'Aberrant regulation of FBW7 in cancer', 'display_name': 'Aberrant regulation of FBW7 in cancer', 'publication_year': 2014, 'publication_date': '2014-03-25', 'ids': {'openalex': 'https://openalex.org/W2132251735', 'doi': 'https://doi.org/10.18632/oncotarget.1859', 'mag': '2132251735', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/24899581', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4039140'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1859', 'pdf_url': 'https://www.oncotarget.com/article/1859/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/1859/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100442919', 'display_name': 'Lixia Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}, {'id': 'https://openalex.org/I4210153519', 'display_name': 'First Affiliated Hospital of Soochow University', 'ror': 'https://ror.org/051jg5p78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153519']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lixia Wang', 'raw_affiliation_strings': ['The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China'], 'affiliations': [{'raw_affiliation_string': 'The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China', 'institution_ids': ['https://openalex.org/I3923682', 'https://openalex.org/I4210153519']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046804560', 'display_name': 'Xiantao Ye', 'orcid': 'https://orcid.org/0000-0002-6370-3323'}, 'institutions': [{'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}, {'id': 'https://openalex.org/I4210153519', 'display_name': 'First Affiliated Hospital of Soochow University', 'ror': 'https://ror.org/051jg5p78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153519']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiantao Ye', 'raw_affiliation_strings': ['The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China'], 'affiliations': [{'raw_affiliation_string': 'The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China', 'institution_ids': ['https://openalex.org/I3923682', 'https://openalex.org/I4210153519']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083085983', 'display_name': 'Yueyong Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1316535847', 'display_name': 'Beth Israel Deaconess Medical Center', 'ror': 'https://ror.org/04drvxt59', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316535847']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yueyong Liu', 'raw_affiliation_strings': ['Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, MA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, MA, USA', 'institution_ids': ['https://openalex.org/I1316535847', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005394879', 'display_name': 'Wenyi Wei', 'orcid': 'https://orcid.org/0000-0003-0512-3811'}, 'institutions': [{'id': 'https://openalex.org/I1316535847', 'display_name': 'Beth Israel Deaconess Medical Center', 'ror': 'https://ror.org/04drvxt59', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316535847']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Wenyi Wei', 'raw_affiliation_strings': ['Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, MA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, MA, USA', 'institution_ids': ['https://openalex.org/I1316535847', 'https://openalex.org/I136199984']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100449964', 'display_name': 'Zhiwei Wang', 'orcid': 'https://orcid.org/0000-0002-6465-7779'}, 'institutions': [{'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}, {'id': 'https://openalex.org/I4210153519', 'display_name': 'First Affiliated Hospital of Soochow University', 'ror': 'https://ror.org/051jg5p78', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210153519']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zhiwei Wang', 'raw_affiliation_strings': ['The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China'], 'affiliations': [{'raw_affiliation_string': 'The Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, the First Affiliated Hospital, Soochow University, Suzhou, China', 'institution_ids': ['https://openalex.org/I3923682', 'https://openalex.org/I4210153519']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5100449964'], 'corresponding_institution_ids': ['https://openalex.org/I3923682', 'https://openalex.org/I4210153519'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.523, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 88, 'citation_normalized_percentile': {'value': 0.999745, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '5', 'issue': '8', 'first_page': '2000', 'last_page': '2015'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13437', 'display_name': 'Mechanisms of cancer metastasis', 'score': 0.977, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5698407}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.5395526}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.4324875}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.34460926}], 'mesh': [{'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016147', 'descriptor_name': 'Genes, Tumor Suppressor', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D044783', 'descriptor_name': 'F-Box Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000073979', 'descriptor_name': 'F-Box-WD Repeat-Containing Protein 7', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016147', 'descriptor_name': 'Genes, Tumor Suppressor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1859', 'pdf_url': 'https://www.oncotarget.com/article/1859/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4039140', 'pdf_url': 'https://europepmc.org/articles/pmc4039140?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039140', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://nrs.harvard.edu/urn-3:HUL.InstRepos:12406786', 'pdf_url': 'https://dash.harvard.edu/bitstream/1/12406786/1/4039140.pdf', 'source': {'id': 'https://openalex.org/S4306401540', 'display_name': 'Digital Access to Scholarship at Harvard (DASH) (Harvard University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I136199984', 'host_organization_name': 'Harvard University', 'host_organization_lineage': ['https://openalex.org/I136199984'], 'host_organization_lineage_names': ['Harvard University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/24899581', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.1859', 'pdf_url': 'https://www.oncotarget.com/article/1859/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.72, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 203, 'referenced_works': ['https://openalex.org/W1487853058', 'https://openalex.org/W1515175646', 'https://openalex.org/W1523933087', 'https://openalex.org/W1523937142', 'https://openalex.org/W1533021978', 'https://openalex.org/W1538085254', 'https://openalex.org/W1538993303', 'https://openalex.org/W1568139490', 'https://openalex.org/W1605937955', 'https://openalex.org/W1690140681', 'https://openalex.org/W1799502400', 'https://openalex.org/W1810265271', 'https://openalex.org/W1820331374', 'https://openalex.org/W1868102126', 'https://openalex.org/W1869025787', 'https://openalex.org/W1869563671', 'https://openalex.org/W1914535044', 'https://openalex.org/W1964898641', 'https://openalex.org/W1965771646', 'https://openalex.org/W1966218963', 'https://openalex.org/W1967903148', 'https://openalex.org/W1968745254', 'https://openalex.org/W1969188594', 'https://openalex.org/W1969430735', 'https://openalex.org/W1969758781', 'https://openalex.org/W1970431885', 'https://openalex.org/W1970797470', 'https://openalex.org/W1970820847', 'https://openalex.org/W1973569665', 'https://openalex.org/W1974096298', 'https://openalex.org/W1976075748', 'https://openalex.org/W1976295398', 'https://openalex.org/W1977168885', 'https://openalex.org/W1978478424', 'https://openalex.org/W1978561866', 'https://openalex.org/W1979577392', 'https://openalex.org/W1980858807', 'https://openalex.org/W1981926952', 'https://openalex.org/W1982030535', 'https://openalex.org/W1982383759', 'https://openalex.org/W1983036561', 'https://openalex.org/W1983614908', 'https://openalex.org/W1983825024', 'https://openalex.org/W1985193869', 'https://openalex.org/W1986630370', 'https://openalex.org/W1987821813', 'https://openalex.org/W1988313248', 'https://openalex.org/W1989214935', 'https://openalex.org/W1989328481', 'https://openalex.org/W1990624451', 'https://openalex.org/W1990738741', 'https://openalex.org/W1990983360', 'https://openalex.org/W1992150326', 'https://openalex.org/W1992447691', 'https://openalex.org/W1992710380', 'https://openalex.org/W1994179903', 'https://openalex.org/W1996754879', 'https://openalex.org/W1997202844', 'https://openalex.org/W1997669934', 'https://openalex.org/W1997952673', 'https://openalex.org/W1999596233', 'https://openalex.org/W2002298463', 'https://openalex.org/W2005635949', 'https://openalex.org/W2008529756', 'https://openalex.org/W2008589883', 'https://openalex.org/W2010164793', 'https://openalex.org/W2010503390', 'https://openalex.org/W2011472720', 'https://openalex.org/W2011848073', 'https://openalex.org/W2015132815', 'https://openalex.org/W2015196212', 'https://openalex.org/W2015553952', 'https://openalex.org/W2015866661', 'https://openalex.org/W2018023136', 'https://openalex.org/W2019826893', 'https://openalex.org/W2021056570', 'https://openalex.org/W2022535887', 'https://openalex.org/W2023434020', 'https://openalex.org/W2023486531', 'https://openalex.org/W2023720312', 'https://openalex.org/W2024930645', 'https://openalex.org/W2029620430', 'https://openalex.org/W2031588422', 'https://openalex.org/W2032306505', 'https://openalex.org/W2033476275', 'https://openalex.org/W2033486224', 'https://openalex.org/W2034375388', 'https://openalex.org/W2038444562', 'https://openalex.org/W2038978453', 'https://openalex.org/W2039164708', 'https://openalex.org/W2041222988', 'https://openalex.org/W2041352318', 'https://openalex.org/W2041949992', 'https://openalex.org/W2041986831', 'https://openalex.org/W2042073539', 'https://openalex.org/W2043563654', 'https://openalex.org/W2044724807', 'https://openalex.org/W2044967196', 'https://openalex.org/W2048113014', 'https://openalex.org/W2048603433', 'https://openalex.org/W2049204580', 'https://openalex.org/W2049480426', 'https://openalex.org/W2049948938', 'https://openalex.org/W2050434028', 'https://openalex.org/W2050455358', 'https://openalex.org/W2050728259', 'https://openalex.org/W2051678809', 'https://openalex.org/W2053427642', 'https://openalex.org/W2053617967', 'https://openalex.org/W2054703855', 'https://openalex.org/W2058654854', 'https://openalex.org/W2059380840', 'https://openalex.org/W2062371417', 'https://openalex.org/W2063893501', 'https://openalex.org/W2064179386', 'https://openalex.org/W2065521655', 'https://openalex.org/W2068646859', 'https://openalex.org/W2071086080', 'https://openalex.org/W2072555538', 'https://openalex.org/W2073590266', 'https://openalex.org/W2073856026', 'https://openalex.org/W2074688366', 'https://openalex.org/W2074740476', 'https://openalex.org/W2075686186', 'https://openalex.org/W2077532831', 'https://openalex.org/W2080520724', 'https://openalex.org/W2081536052', 'https://openalex.org/W2082983359', 'https://openalex.org/W2083444134', 'https://openalex.org/W2084831115', 'https://openalex.org/W2084910801', 'https://openalex.org/W2085432002', 'https://openalex.org/W2085682228', 'https://openalex.org/W2086677653', 'https://openalex.org/W2087050587', 'https://openalex.org/W2087812655', 'https://openalex.org/W2088005829', 'https://openalex.org/W2088214323', 'https://openalex.org/W2088986869', 'https://openalex.org/W2089476895', 'https://openalex.org/W2090263169', 'https://openalex.org/W2091503085', 'https://openalex.org/W2092950531', 'https://openalex.org/W2093075930', 'https://openalex.org/W2093775600', 'https://openalex.org/W2094707025', 'https://openalex.org/W2095347109', 'https://openalex.org/W2097933346', 'https://openalex.org/W2098647609', 'https://openalex.org/W2101722818', 'https://openalex.org/W2102261319', 'https://openalex.org/W2102577577', 'https://openalex.org/W2104269122', 'https://openalex.org/W2105010725', 'https://openalex.org/W2105150792', 'https://openalex.org/W2105312329', 'https://openalex.org/W2105493915', 'https://openalex.org/W2107372813', 'https://openalex.org/W2111084458', 'https://openalex.org/W2112357436', 'https://openalex.org/W2112658436', 'https://openalex.org/W2112767263', 'https://openalex.org/W2118512985', 'https://openalex.org/W2118645968', 'https://openalex.org/W2121333393', 'https://openalex.org/W2124348926', 'https://openalex.org/W2126344344', 'https://openalex.org/W2128451702', 'https://openalex.org/W2128775512', 'https://openalex.org/W2132399813', 'https://openalex.org/W2133098474', 'https://openalex.org/W2134062610', 'https://openalex.org/W2135471999', 'https://openalex.org/W2136399408', 'https://openalex.org/W2136752130', 'https://openalex.org/W2137005364', 'https://openalex.org/W2138779676', 'https://openalex.org/W2138888816', 'https://openalex.org/W2142183096', 'https://openalex.org/W2142260259', 'https://openalex.org/W2146677771', 'https://openalex.org/W2148619913', 'https://openalex.org/W2149746235', 'https://openalex.org/W2153096597', 'https://openalex.org/W2153909821', 'https://openalex.org/W2154830487', 'https://openalex.org/W2154894786', 'https://openalex.org/W2155080972', 'https://openalex.org/W2155458687', 'https://openalex.org/W2157029838', 'https://openalex.org/W2159892503', 'https://openalex.org/W2163169932', 'https://openalex.org/W2165804364', 'https://openalex.org/W2166779556', 'https://openalex.org/W2168314151', 'https://openalex.org/W2169388604', 'https://openalex.org/W2169915014', 'https://openalex.org/W2170275592', 'https://openalex.org/W2315613727', 'https://openalex.org/W2332971183', 'https://openalex.org/W338483294', 'https://openalex.org/W4243907588', 'https://openalex.org/W4246711311'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': {'//': [0, 65, 69], 'Lixia': [1], 'Wang': [2, 18], '1,*': [3, 7], ',': [4, 8, 12, 16, 20], 'Xiantao': [5], 'Ye': [6], 'Yueyong': [9], 'Liu': [10], '2': [11, 15, 39], 'Wenyi': [13, 62], 'Wei': [14], 'Zhiwei': [17, 66], '1': [19, 21], 'The': [22], 'Cyrus': [23], 'Tang': [24], 'Hematology': [25], 'Center,': [26, 47], 'Jiangsu': [27], 'Institute': [28], 'of': [29, 41, 114], 'Hematology,': [30], 'the': [31, 109, 157], 'First': [32], 'Affiliated': [33], 'Hospital,': [34], 'Soochow': [35], 'University,': [36], 'Suzhou,': [37], 'China': [38], 'Department': [40], 'Pathology,': [42], 'Beth': [43], 'Israel': [44], 'Deaconess': [45], 'Medical': [46, 49], 'Harvard': [48], 'School,': [50], 'MA,': [51], 'USA': [52], '*': [53], 'These': [54], 'authors': [55], 'contributed': [56], 'equally': [57], 'to': [58], 'this': [59], 'work': [60], 'Correspondence:': [61], 'Wei,': [63], 'email:': [64, 68], 'Wang,': [67], 'Keywords': [70], ':cancer,': [71], 'tumor': [72, 105, 159], 'suppressor,': [73, 106], 'FBW7,': [74], 'SCF,': [75], 'ubiquitination,': [76], 'oncoprotein': [77], 'Received': [78], ':': [79, 84, 89], 'March': [80, 85, 90], '13,': [81], '2014': [82, 87, 92], 'Accepted': [83], '24,': [86], 'Published': [88], '25,': [91], 'Abstract': [93], 'FBW7': [94, 128, 171], '(F-box': [95], 'and': [96, 111, 124, 141, 153], 'WD': [97], 'repeat': [98], 'domain-containing': [99], '7)': [100], 'or': [101, 164], 'Fbxw7': [102], 'is': [103, 129, 161, 173], 'a': [104, 174], 'which': [107], 'promotes': [108], 'ubiquitination': [110], 'subsequent': [112], 'degradation': [113], 'numerous': [115], 'oncoproteins': [116], 'including': [117, 135], 'Mcl-1,': [118], 'Cyclin': [119], 'E,': [120], 'Notch,': [121], 'c-': [122], 'Jun,': [123], 'c-Myc.': [125], 'In': [126], 'turn,': [127], 'regulated': [130], 'by': [131, 146], 'multiple': [132], 'upstream': [133], 'factors': [134], 'p53,': [136], 'C/EBP-δ,': [137], 'EBP2,': [138], 'Pin1,': [139], 'Hes-5': [140], 'Numb4': [142], 'as': [143, 145, 149], 'well': [144], 'microRNAs': [147], 'such': [148], 'miR-223,': [150], 'miR-27a,': [151], 'miR-25,': [152], 'miR-129-5p.': [154], 'Given': [155], 'that': [156], 'Fbw7': [158], 'suppressor': [160], 'frequently': [162], 'inactivated': [163], 'deleted': [165], 'in': [166], 'various': [167], 'human': [168], 'cancers,': [169], 'targeting': [170], 'regulators': [172], 'promising': [175], 'anti-cancer': [176], 'therapeutic': [177], 'strategy.': [178], '&nbsp': [179]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2132251735', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 15}, {'year': 2014, 'cited_by_count': 2}], 'updated_date': '2024-12-24T13:51:42.847252', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
