Title: Contact allergy to oxidized <i>d</i>‐limonene among dermatitis patients
Abstract: d ‐Limonene. obtained as a by‐product from the citrus juice industry was introduced on the market as a more environmentally friendly defatting and cleaning agent than the traditionally used organic solvents. Autoxidation of d ‐limonene readily occurs to give a variety of oxygenated monocyclic terpenes that are strong contact allergens. The aim of the present study was to investigate the prevalence of contact allergy to air exposed d‐limonene among dermatitis patients. A fraction consisting of d‐limonene hydroperoxides was also tested. Screening with oxidized d‐limonene will detect cases of allergic contact dermatitis. Additional cases were detected when testing with the fraction of limonene hydroperoxides. The proportion of positive patch test reactions to oxidized d‐limonene was comparable to that seen for several of the allergens within the standard series. An increased UAT of d‐limonene containing allergenic oxidation products in industry where high concentrations are used, as well as in domestic exposure, might result in contact sensitization and dermatitis. Patients reacting to d‐limonene often reacted to fragrance mix, balsam of Peru and colophony in the standard series.
Publication Year: 1997
Publication Date: 1997-04-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 158
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot