Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2131074536', 'doi': 'https://doi.org/10.1016/0091-6749(87)90215-6', 'title': 'The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man*1', 'display_name': 'The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man*1', 'publication_year': 1987, 'publication_date': '1987-05-01', 'ids': {'openalex': 'https://openalex.org/W2131074536', 'doi': 'https://doi.org/10.1016/0091-6749(87)90215-6', 'mag': '2131074536', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3553279'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0091-6749(87)90215-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S108525051', 'display_name': 'Journal of Allergy and Clinical Immunology', 'issn_l': '0091-6749', 'issn': ['0091-6749', '1085-8725', '1097-6825'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5008203993', 'display_name': 'Neil Barnes', 'orcid': 'https://orcid.org/0000-0001-7981-5197'}, 'institutions': [{'id': 'https://openalex.org/I14746517', 'display_name': 'Royal College of Surgeons of England', 'ror': 'https://ror.org/02qrg5a24', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I14746517']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': True, 'raw_author_name': 'N BARNES', 'raw_affiliation_strings': ['From the Department of Pharmacology, Royal College of Surgeons of England, London, England', "From the Department of Thoracic Medicine, King's College School of Medicine and Dentistry, London, England"], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pharmacology, Royal College of Surgeons of England, London, England', 'institution_ids': ['https://openalex.org/I14746517']}, {'raw_affiliation_string': "From the Department of Thoracic Medicine, King's College School of Medicine and Dentistry, London, England", 'institution_ids': ['https://openalex.org/I241749']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5008203993'], 'corresponding_institution_ids': ['https://openalex.org/I14746517', 'https://openalex.org/I241749'], 'apc_list': {'value': 4000, 'currency': 'USD', 'value_usd': 4000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.842, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 89, 'citation_normalized_percentile': {'value': 0.850696, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '79', 'issue': '5', 'first_page': '816', 'last_page': '821'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10051', 'display_name': 'Asthma and respiratory diseases', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10051', 'display_name': 'Asthma and respiratory diseases', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10877', 'display_name': 'Allergic Rhinitis and Sensitization', 'score': 0.9937, 'subfield': {'id': 'https://openalex.org/subfields/2723', 'display_name': 'Immunology and Allergy'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11651', 'display_name': 'Inhalation and Respiratory Drug Delivery', 'score': 0.9859, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/leukotriene-d4', 'display_name': 'Leukotriene D4', 'score': 0.86531126}], 'concepts': [{'id': 'https://openalex.org/C2780769369', 'wikidata': 'https://www.wikidata.org/wiki/Q4375', 'display_name': 'Bronchoconstriction', 'level': 3, 'score': 0.97974217}, {'id': 'https://openalex.org/C2777242621', 'wikidata': 'https://www.wikidata.org/wiki/Q647917', 'display_name': 'Leukotriene D4', 'level': 4, 'score': 0.86531126}, {'id': 'https://openalex.org/C1122143', 'wikidata': 'https://www.wikidata.org/wiki/Q61233', 'display_name': 'Histamine', 'level': 2, 'score': 0.81692266}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.69633555}, {'id': 'https://openalex.org/C2776452501', 'wikidata': 'https://www.wikidata.org/wiki/Q424190', 'display_name': 'Leukotriene', 'level': 3, 'score': 0.5926201}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.59059864}, {'id': 'https://openalex.org/C27081682', 'wikidata': 'https://www.wikidata.org/wiki/Q269829', 'display_name': 'Placebo', 'level': 3, 'score': 0.52070624}, {'id': 'https://openalex.org/C2777383412', 'wikidata': 'https://www.wikidata.org/wiki/Q4770891', 'display_name': 'Antagonism', 'level': 3, 'score': 0.4893181}, {'id': 'https://openalex.org/C2776954882', 'wikidata': 'https://www.wikidata.org/wiki/Q840343', 'display_name': 'Inhalation', 'level': 2, 'score': 0.4419776}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.41612872}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.34886676}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.3337483}, {'id': 'https://openalex.org/C2776042228', 'wikidata': 'https://www.wikidata.org/wiki/Q35869', 'display_name': 'Asthma', 'level': 2, 'score': 0.31529546}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.050437927}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.048968405}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001986', 'descriptor_name': 'Bronchial Spasm', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D006632', 'descriptor_name': 'Histamine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010654', 'descriptor_name': 'Phenylbutyrates', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001986', 'descriptor_name': 'Bronchial Spasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006632', 'descriptor_name': 'Histamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010654', 'descriptor_name': 'Phenylbutyrates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011897', 'descriptor_name': 'Random Allocation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012129', 'descriptor_name': 'Respiratory Function Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013189', 'descriptor_name': 'SRS-A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013189', 'descriptor_name': 'SRS-A', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0091-6749(87)90215-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S108525051', 'display_name': 'Journal of Allergy and Clinical Immunology', 'issn_l': '0091-6749', 'issn': ['0091-6749', '1085-8725', '1097-6825'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3553279', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.79, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 24, 'referenced_works': ['https://openalex.org/W1862464476', 'https://openalex.org/W1887738083', 'https://openalex.org/W1929987550', 'https://openalex.org/W1969555049', 'https://openalex.org/W1979349548', 'https://openalex.org/W1979725242', 'https://openalex.org/W1982778295', 'https://openalex.org/W1983217455', 'https://openalex.org/W1988831361', 'https://openalex.org/W2004305634', 'https://openalex.org/W2011793087', 'https://openalex.org/W2027449828', 'https://openalex.org/W2047035798', 'https://openalex.org/W2049796670', 'https://openalex.org/W2050252686', 'https://openalex.org/W2052828945', 'https://openalex.org/W2066950125', 'https://openalex.org/W2072425850', 'https://openalex.org/W2075270092', 'https://openalex.org/W2083925466', 'https://openalex.org/W2096786832', 'https://openalex.org/W2107052422', 'https://openalex.org/W2123773797', 'https://openalex.org/W2160457267'], 'related_works': ['https://openalex.org/W2353244414', 'https://openalex.org/W2166915910', 'https://openalex.org/W2160457267', 'https://openalex.org/W2072440963', 'https://openalex.org/W2068840900', 'https://openalex.org/W2054604027', 'https://openalex.org/W2043770111', 'https://openalex.org/W2026156721', 'https://openalex.org/W1996220664', 'https://openalex.org/W1905861166'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2131074536', 'counts_by_year': [{'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-16T11:09:59.011848', 'created_date': '2016-06-24'}