Publication Information

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2742, 2746, 2757, 2812, 2815, 2827, 2835, 2928, 2947, 2969, 3011, 3021, 3064, 3071, 3109, 3121, 3124, 3133, 3136, 3144, 3155, 3170, 3199, 3261, 3281, 3292, 3302, 3375, 3460, 3476, 3484, 3510, 3544, 3559, 3611, 3621, 3624, 3636, 3661, 3689, 3692, 3737, 3744, 3755, 3769, 3783, 3811, 3817, 3821, 3858, 3866, 3889, 3897, 3919, 3928, 3944, 3953, 3972, 3997, 4004, 4013, 4022, 4057, 4069, 4086, 4092, 4098, 4116, 4124, 4128, 4135, 4146, 4163, 4168, 4181, 4212, 4240], 'the': [6, 12, 86, 93, 102, 105, 124, 143, 165, 169, 203, 209, 283, 290, 299, 302, 321, 340, 362, 366, 516, 570, 594, 609, 703, 855, 1059, 1150, 1163, 1169, 1176, 1205, 1309, 1429, 1552, 1624, 1627, 1647, 1652, 1657, 1662, 1665, 1675, 1700, 1708, 1717, 1733, 1750, 1794, 1801, 1811, 1892, 1903, 1912, 1916, 1938, 1957, 1965, 1994, 2002, 2016, 2020, 2143, 2218, 2226, 2325, 2360, 2411, 2417, 2431, 2454, 2496, 2531, 2542, 2660, 2665, 2704, 2728, 2743, 2828, 2863, 2921, 2938, 2951, 2972, 2977, 2980, 2989, 2996, 3004, 3008, 3015, 3029, 3037, 3044, 3061, 3086, 3099, 3159, 3171, 3268, 3293, 3312, 3353, 3362, 3371, 3376, 3497, 3503, 3517, 3521, 3563, 3599, 3731, 3742, 3770, 3812, 3818, 3859, 3929, 3934, 3998, 4002, 4005, 4020, 4031, 4047, 4054, 4083, 4087, 4114, 4125, 4152, 4169, 4191, 4223, 4237], 'mitochondrial': [7, 17, 204, 214, 438, 545, 629, 828, 846, 886, 1114, 1126, 1137, 1223, 1423, 1784, 2601], 'inner': [8, 205], 'membranes': [9, 206, 439, 518], 'contributing': [10, 207], 'to': [11, 24, 100, 117, 208, 221, 297, 314, 502, 695, 1203, 1337, 1412, 1440, 1488, 1673, 1748, 1827, 1910, 1928, 2191, 2205, 2235, 2323, 2359, 2466, 2489, 2514, 2649, 2753, 2905, 3060, 3370, 3598, 3633, 3654, 3714, 3798, 3942, 4009, 4016, 4044, 4053, 4072, 4151, 4185], 'regulation': [13, 210], 'multiple': [15, 188, 212, 385, 599, 751, 1136, 1265, 1831, 1984, 2039, 3289], 'discrete': [16, 213], 'functions.': [18, 215], 'Here,': [19, 216], 'we': [20, 139, 217, 336, 1078, 1436, 1823, 1992], 'extend': [21, 218], 'shotgun': [22, 39, 219, 236, 1464, 1615, 1825, 1844, 1895], 'lipidomics': [23, 40, 220, 237, 1102, 1465, 1596, 1616, 1772, 1826, 1845, 1896, 2589], 'identify': [25, 222, 1338, 1413, 1828], 'and': [26, 123, 141, 158, 164, 223, 320, 338, 355, 361, 424, 479, 494, 584, 708, 729, 740, 768, 788, 807, 848, 880, 888, 892, 912, 982, 1025, 1140, 1158, 1281, 1295, 1339, 1363, 1414, 1549, 1606, 1610, 1629, 1731, 1829, 1934, 1991, 2009, 2015, 2055, 2085, 2099, 2116, 2125, 2147, 2172, 2181, 2245, 2259, 2307, 2337, 2388, 2397, 2406, 2413, 2427, 2447, 2473, 2480, 2525, 2538, 2547, 2560, 2685, 2709, 2714, 2806, 2818, 2833, 2860, 2883, 2935, 2975, 3013, 3046, 3098, 3140, 3174, 3186, 3213, 3352, 3520, 3540, 3602, 3627, 3664, 3824, 3839, 3856, 3885, 3956, 3978, 4094, 4199], 'quantitate': [27, 224, 1204, 1830], 'cardiolipin': [28, 45, 99, 114, 133, 149, 185, 225, 242, 296, 311, 330, 346, 382, 529, 573, 613, 653, 685, 707, 733, 844, 874, 878, 911, 1056, 1081, 1104, 1133, 1154, 1209, 1256, 1299, 1334, 1341, 1355, 1377, 1409, 1416, 1430, 1755, 1774, 1813, 1833, 1850, 1898, 1909, 1925, 1947, 1986, 1998, 2036, 2052, 2057, 2070, 2315, 2347, 2505, 2591, 2717, 3072, 3078, 3145, 3264, 3551, 3658, 3718, 3773, 4024, 4118, 4130, 4214], 'molecular': [29, 46, 115, 134, 145, 226, 243, 312, 331, 342, 405, 508, 530, 574, 614, 654, 734, 881, 1177, 1257, 1335, 1342, 1378, 1410, 1417, 1445, 1631, 1659, 1683, 1735, 1752, 1807, 1834, 1851, 1926, 1948, 1987, 1999, 2071, 2506, 2718, 3073, 3146, 3265, 3552, 3659, 3719, 3774, 3886, 3891, 4025, 4119, 4131], 'species': [30, 47, 146, 227, 244, 343, 406, 531, 575, 615, 655, 882, 1178, 1258, 1343, 1379, 1418, 1446, 1632, 1660, 1684, 1736, 1753, 1808, 1835, 1852, 1988, 2000, 2072, 3266, 3638, 3775, 3887, 3892, 4026, 4120, 4215], 'directly': [31, 150, 228, 347, 1454, 1475, 1519, 1555, 1836, 2625, 2787, 2919, 3234, 3862, 3893], 'from': [32, 111, 151, 229, 308, 348, 722, 1348, 1455, 1476, 1520, 1556, 1837, 1922, 1956, 2062, 2123, 2150, 2217, 2376, 2391, 2410, 2461, 2626, 2669, 2706, 2739, 2788, 3075, 3235, 3364, 3593, 3631, 3815, 3863, 3894, 4042, 4159], 'lipid': [33, 152, 230, 349, 1187, 1346, 1424, 1444, 1456, 1838, 2003, 2257, 2558, 2645, 2677, 2697, 2722, 2829, 2836, 2914, 3895], 'extracts': [34, 153, 231, 350, 1347, 1425, 1478, 1558, 1839, 2004, 2281, 2678, 3865, 3896], 'biological': [36, 233, 558, 712, 754, 1449, 1480, 1521, 1560, 1841, 2627, 2789, 3236, 3594, 3867, 3898], 'samples.': [37, 234, 1842], 'Three': [38, 80, 235, 277, 1843, 1886], 'approaches': [41, 179, 238, 376, 1846, 2030], 'for': [42, 85, 175, 181, 239, 282, 372, 378, 569, 1065, 1308, 1715, 1721, 1800, 1847, 1891, 1897, 2026, 2032, 2113, 2117, 2502, 2521, 2689, 2703, 2899, 2956, 3164, 3489, 3549, 3568, 3761, 4113, 4188], 'analyses': [43, 240, 1330, 1471, 1848, 2839, 3120, 3132, 3143, 3380, 3459, 3620, 3676, 3952], 'were': [48, 83, 245, 280, 525, 1259, 1853, 1889, 2060, 2073, 2121, 2136, 2148, 2179, 2189, 2238, 2282, 2317, 2357, 2374, 2394, 2408, 2437, 2451, 2487, 2536, 2679, 2823, 2840, 2908, 3049, 3178, 3284, 3381, 3416, 3462, 3524, 3596, 3671, 3721, 3728, 3827, 3837, 3923, 3960, 4051, 4079, 4233], 'developed': [49, 246, 1437, 1854], 'using': [50, 191, 247, 388, 662, 1386, 1601, 1685, 1855, 1915, 2042, 2221, 2272, 3253, 3267, 3288, 3467, 3587, 3643, 3780, 3801, 3925, 4190], 'either': [51, 60, 192, 248, 257, 389, 1856, 1866, 2043, 2151], 'continuous': [53, 250, 1858], 'ion-transmission': [54, 251, 1859], 'instrument': [55, 74, 252, 271, 1860, 3270, 3404, 3642, 3740], '(i.e.,': [56, 253, 1883, 2499, 3056, 3975, 3985, 4001, 4208], 'triple-quadrupole': [57, 254, 1862], 'type)': [58, 255], 'with': [59, 256, 1113, 1199, 1641, 1783, 1865, 2229, 2292, 2335, 2363, 2399, 2423, 2443, 2600, 2682, 2825, 2855, 2862, 2931, 3018, 3052, 3194, 3346, 3398, 3407, 3506, 3526, 3577, 4082, 4089, 4133], 'low': [61, 166, 258, 363, 1868, 2017, 3272, 3645, 4225], 'or': [62, 67, 259, 264, 1196, 1422, 1681, 1687, 1869, 1874, 2142, 2156, 2163], 'high': [63, 69, 260, 266, 1870, 1876], 'mass': [64, 70, 195, 261, 267, 392, 665, 1206, 1305, 1389, 1484, 1527, 1546, 1579, 1608, 1676, 1690, 1871, 1877, 1881, 2046, 2097, 2118, 2633, 2795, 2845, 2906, 2993, 3009, 3034, 3054, 3201, 3242, 3273, 3387, 3508, 3618, 3646, 3698, 3735, 3756, 3764, 3853, 3904, 3920, 4194], 'resolution': [65, 71, 262, 268, 1872, 1878, 3274, 3647, 3736, 3757], 'settings': [66, 263, 2898, 3415], 'hybrid': [72, 269, 1879], 'pulsed': [73, 270, 1880], '[i.e.,': [75, 272, 1861], 'quadrupole': [76, 273, 2974, 3006, 3505], 'time-of-flight': [77, 274, 3528], '(QqTOF)': [78, 275], 'type].': [79, 276], 'chemical': [81, 278, 741, 1266, 1274, 1887, 2134], 'principles': [82, 279, 1888], 'used': [84, 281, 1192, 1406, 1670, 1747, 1890, 2338, 2955, 3163, 3305, 3488, 3548, 3567, 4187], 'development': [87, 284, 1893], 'these': [89, 137, 178, 286, 334, 375, 1254, 1979, 2029, 2354, 3793, 3964], 'approaches.': [90, 287], 'These': [91, 288, 1900, 3669, 4102], 'include': [92, 289, 1901], 'marked': [94, 291, 1904], 'enrichment': [95, 292, 1905], 'linoleate': [97, 294, 604, 1907], 'in': [98, 131, 184, 187, 295, 328, 381, 384, 419, 437, 440, 515, 544, 576, 598, 608, 628, 656, 683, 726, 845, 863, 867, 877, 914, 943, 978, 990, 1058, 1085, 1106, 1124, 1134, 1142, 1155, 1161, 1222, 1300, 1344, 1380, 1419, 1614, 1776, 1810, 1908, 1945, 1964, 2001, 2035, 2038, 2175, 2276, 2289, 2319, 2593, 2672, 2878, 2886, 2937, 2950, 2971, 2979, 2988, 2995, 3007, 3028, 3036, 3085, 3158, 3324, 3516, 3562, 3932, 3967, 3990, 4030, 4037, 4075, 4202, 4222], 'maximize': [101, 298, 1911], 'signal-to-noise': [103, 300, 1913], 'ratio,': [104, 301, 1914], 'specific': [106, 144, 303, 341, 753, 1697, 1917, 1995], 'neutral': [107, 304, 1918, 3040, 3057, 3062, 3130], 'loss': [108, 305, 1919, 3041, 3063, 3131], 'ketenes': [110, 307, 1921], 'doubly': [112, 119, 125, 309, 316, 322, 1332, 1923, 1930, 1939, 3076, 3262, 3656, 3771], 'charged': [113, 120, 126, 310, 317, 323, 1333, 1408, 1924, 1931, 1940, 3077, 3263, 3657, 3717, 3772], 'ions': [116, 313, 1336, 1411, 1927, 3079, 3660, 3670, 3720, 3814], 'yield': [118, 315, 1929], 'triacyl': [121, 318, 1932], 'monolysocardiolipins,': [122, 319, 1933], 'character': [127, 324, 1941], 'two': [129, 326, 413, 1943, 3322, 3331, 3650, 4213], 'phosphates': [130, 327, 1944], 'each': [132, 329, 404, 1946, 2200, 2392, 2462, 2490, 2515, 2957, 3165, 3490, 3569, 3637, 3816], 'species.': [135, 332, 735, 1949, 2507, 2719, 3553], 'Through': [136, 333, 1707, 1978], 'techniques,': [138, 335, 1980], 'identified': [140, 337, 1261, 1993], 'quantified': [142, 339], 'profiles': [147, 344, 1996], 'mouse': [155, 352, 1087, 2006, 2393, 2522, 2725, 2747], 'heart,': [156, 353, 603, 684, 2007, 2386, 2523, 2707], 'liver,': [157, 354, 2008, 2387, 2524, 2708], 'skeletal': [159, 356, 2010, 2389, 2526], 'muscle.': [160, 357, 2011], 'The': [161, 358, 477, 699, 766, 840, 1130, 2012, 2187, 2280, 2313, 2377, 2383, 2508, 2676, 2749, 2897, 2912, 3089, 3257, 3300, 3340, 3355, 3403, 3412, 3530, 3734, 3766, 3809, 4033, 4064, 4144, 4165, 4177, 4218], 'accuracy': [162, 359, 2013, 4145], '(∼5%)': [163, 360, 2014], 'end': [167, 364, 2018], 'linear': [170, 367, 1718, 2021, 4110, 4153, 4170], 'dynamic': [171, 368, 1719, 2022, 4111], 'range': [172, 369, 1720, 2023, 3010, 3971, 4041, 4112, 4180, 4227], '(10': [173, 370, 2024], 'fmol/μl)': [174, 371, 2025], 'quantitation': [176, 373, 1550, 1722, 1803, 1982, 2027, 2503, 3857, 4115, 4147, 4171, 4189], 'make': [177, 374, 2028], 'useful': [180, 377, 2031], 'studying': [182, 379, 2033], 'alterations': [183, 380, 2034], 'metabolism': [186, 383, 1057, 2037], 'disease': [189, 386, 1167, 2040], 'states': [190, 387, 2041], 'type': [193, 390, 2044], 'spectrometer.': [196, 393, 2047], '(1,3-diphosphatidyl-sn-glycerol)': [395], 'unique': [398, 738], 'class': [399, 1356, 1431, 1635, 1648, 1663, 1701, 1814], 'anionic': [401], 'phospholipids,': [402, 2049], 'because': [403], 'composed': [408], 'dimer': [411], 'phosphatidyl': [414], 'moieties,': [415, 423], 'three': [416, 420, 3337], 'chiral': [417], 'centers': [418], 'distinct': [421, 507], 'glycerol': [422], 'four': [425, 3612], 'fatty': [426, 523, 567, 3125], 'acyl': [427, 610, 3126], 'chains.': [428], 'predominantly,': [431], 'if': [432, 519], 'not': [433, 1816, 3678, 3724], 'nearly': [434], 'exclusively,': [435], 'present': [436, 514, 606, 1809], 'eukaryotic': [441], 'cells': [442, 1144], '(1van': [443], 'Klompenburg': [444], 'W.': [445, 786], 'Nilsson': [446], 'I.': [447, 541, 625, 1219], 'von': [448], 'Heijne': [449], 'G.': [450], 'de': [451], 'Kruijff': [452], 'B.': [453, 903, 969], 'Anionic': [454], 'phospholipids': [455, 3693], 'are': [456, 1636, 1669, 3605], 'determinants': [457], 'membrane': [459, 1277, 2881], 'protein': [460, 2520, 2532, 2655, 2662, 2670, 2808, 3581, 3600], 'topology.EMBO': [461], 'J.': [462, 1015, 1031, 1092, 1508, 1762, 2261, 2562, 2579, 2614, 2776, 3223], '1997;': [463], '16:': [464], '4261-4266Crossref': [465], 'PubMed': [466, 489, 552, 636, 677, 778, 795, 817, 835, 923, 950, 1003, 1072, 1119, 1230, 1248, 1319, 1401, 1500, 1533, 1567, 1590, 1789, 2107, 2267, 2568, 2606, 2639, 2801, 2892, 3248, 3707, 3874, 3910], 'Scopus': [467, 490, 553, 637, 678, 779, 796, 818, 836, 924, 951, 1004, 1037, 1073, 1120, 1231, 1249, 1320, 1402, 1501, 1534, 1568, 1591, 1790, 2108, 2268, 2569, 2607, 2640, 2802, 2893, 3249, 3708, 3875, 3911], '(173)': [468], 'Google': [469, 492, 555, 639, 680, 781, 798, 820, 838, 926, 953, 1006, 1039, 1075, 1122, 1233, 1251, 1322, 1404, 1503, 1536, 1570, 1593, 1792, 2110, 2270, 2571, 2609, 2642, 2804, 2895, 3251, 3710, 3877, 3913], 'Scholar,': [470, 640, 782, 799, 821, 927, 954, 1007, 1040, 1234, 1504, 1537, 1571, 2610, 3878], '2Schlame': [471, 760], 'M.': [472, 533, 535, 617, 619, 761, 804, 929, 1017, 1211, 1213], 'Rua': [473, 762], 'D.': [474, 763], 'Greenberg': [475, 538, 622, 764, 1053, 1216], 'M.L.': [476, 539, 623, 765, 1054, 1217], 'biosynthesis': [478, 571, 767], 'functional': [480, 769], 'role': [481, 746, 770, 842, 1160], 'cardiolipin.Prog.': [483, 772], 'Lipid': [484, 667, 773, 1391, 1490], 'Res.': [485, 668, 774, 918, 1392, 1491], '2000;': [486, 775, 920], '39:': [487, 776], '257-288Crossref': [488, 777], '(665)': [491, 780], 'Scholar),': [493, 1123, 1793, 2572], 'its': [495, 709, 745, 1159, 3365], 'genetic': [496, 859, 865], 'ancestry': [497], 'can': [498, 1723], 'be': [499, 513, 1724, 3777, 3799, 4186], 'traced': [500], 'back': [501], 'bacterial': [503], 'membranes.': [504], 'Thousands': [505], 'species,': [509], 'including': [510, 2050, 2385, 3204], 'regioisomers,': [511], 'would': [512], 'cellular': [517, 1186, 1473, 1517, 1553, 1583, 2623, 2785, 3232, 3860], 'all': [520, 1655, 3550, 3603], 'naturally': [521], 'occurring': [522], 'acids': [524, 568], 'randomly': [526], 'incorporated': [527], 'into': [528, 2349, 2439, 2920], '(3Schlame': [532, 616, 1210], 'Ren': [534, 618, 1212], 'Xu': [536, 620, 1214], 'Y.': [537, 621, 1215], 'Haller': [540, 624, 1218], 'Molecular': [542, 626, 1220], 'symmetry': [543, 627, 1221], 'cardiolipins.Chem.': [546, 630, 1224], 'Phys.': [547, 631, 812, 1225], 'Lipids.': [548, 632, 813, 1226], '2005;': [549, 633, 669, 1116, 1227, 1393, 1564, 1587, 1786, 2603, 3871], '138:': [550, 634, 1228], '38-49Crossref': [551, 635, 1229], '(235)': [554, 638, 1232], 'Scholar).': [556, 681, 839, 1076, 1252, 1594, 2111, 2643, 2896, 3711, 3914], 'However,': [557, 3752], 'organisms': [559], 'selectively': [560], 'use': [561, 1709], 'very': [563, 4204, 4224], 'limited': [564], 'array': [565, 1611], 'stereoselective': [578], 'manner': [579], 'that': [580, 743, 1080, 1183, 3759, 3922, 3943, 3988, 4105, 4134, 4156], 'species-,': [582], 'organ-,': [583], 'cell': [585, 808], 'type-specific.': [586], 'This': [587], 'accomplished': [589, 1618, 1990], 'through': [590, 854, 1737], 'remodeling': [591, 909, 2882], 'enzymes': [592], '(e.g.,': [593, 3275, 3321, 4027, 4228], 'tazaffins),': [595], 'which': [596, 864, 1125, 1271, 1694, 2764, 3359, 3933], 'exist': [597], 'splice': [600], 'variants.': [601], 'In': [602, 717, 1253, 1360, 1623, 1651, 1820], 'predominantly': [607], 'chains': [611], '4Sparagna': [641], 'G.C.': [642, 1366], 'Johnson': [643, 1367], 'C.A.': [644, 1368], 'McCune': [645, 1369], 'S.A.': [646, 1370], 'Moore': [647, 1371], 'R.L.': [648, 1372], 'Murphy': [649, 1373], 'R.C.': [650, 1374], 'Quantitation': [651, 1375, 1613], 'spontaneously': [657, 1381], 'hypertensive': [658, 1382], 'heart': [659, 1383], 'failure': [660, 1384], 'rats': [661, 1385], 'electrospray': [663, 1303, 1325, 1387, 1525, 1544, 2631, 2793, 2857, 3240, 3400, 3695, 3851, 3901], 'ionization': [664, 1304, 1326, 1388, 1526, 1545, 2632, 2794, 3241, 3696, 3852, 3902], 'spectrometry.J.': [666, 1390, 3699], '46:': [670, 1394], '1196-1204Abstract': [671, 1395], 'Full': [672, 674, 998, 1000, 1396, 1398, 1495, 1497], 'Text': [673, 675, 999, 1001, 1397, 1399, 1496, 1498], 'PDF': [676, 1002, 1400, 1499], '(127)': [679, 1403], 'Therefore,': [682, 3792], 'represents': [686, 3758], 'an': [687, 748, 810, 1029, 1438, 1972, 2277, 2350, 2856, 2967, 3019, 3399, 4182, 4242], 'enriched': [688], 'storage': [689], 'depot': [690], 'linoleic': [692], 'acid': [693, 2087, 3580], 'relative': [694], 'other': [696, 1185, 1679, 1960, 2133], 'phospholipid': [697, 2879], 'classes.': [698, 1188], 'biochemical': [700], 'mechanisms': [701], 'underlying': [702], 'production': [704], 'linoleate-enriched': [706], 'effects': [710], 'on': [711, 1756, 2453, 2530, 2659, 2768, 2842, 3384, 3639], 'function': [713, 847, 1157], 'remain': [714], 'incompletely': [715], 'understood.': [716], 'large': [718], 'part,': [719], 'this': [720, 868, 1458, 1711, 1738, 1742, 1798, 1821, 3753, 4076], 'results': [721, 2772, 2877, 4034, 4103], 'previous': [723, 2770], 'technical': [724], 'difficulties': [725], 'accurately': [727], 'identifying': [728], 'quantifying': [730], 'low-abundance': [731, 1680, 1806, 1832, 1985], 'individual': [732, 1443, 1805, 4117], 'possesses': [737], 'physical': [739], 'properties': [742], 'promote': [744], 'as': [747, 1463, 1671, 1969, 1971, 2164, 2573, 2667, 2736, 2821, 2910, 3104, 3217, 3589, 3607, 3680, 3842, 4210], 'effector': [749], 'highly': [752], 'functions': [755, 1139, 3291, 3304], '(for': [756], 'recent': [757], 'reviews,': [758], 'see': [759], '5McMillin': [783], 'J.B.': [784], 'Dowhan': [785], 'apoptosis.Biochim.': [789], 'Biophys.': [790, 917], 'Acta.': [791], '2002;': [792, 947, 995, 1316], '1585:': [793], '97-107Crossref': [794], '(240)': [797], '6Cristea': [800], 'I.M.': [801], 'Degli': [802], 'Esposti': [803], 'Membrane': [805], 'lipids': [806, 1963, 3461], 'death:': [809], 'overview.Chem.': [811], '2004;': [814, 832, 1034, 1069, 1530, 2636, 2798, 2889, 3245], '129:': [815], '133-160Crossref': [816], '(71)': [819], '7Hatch': [822], 'G.M.': [823], 'Cell': [824, 830], 'biology': [825], 'cardiac': [827, 849], 'phospholipids.Biochem.': [829], 'Biol.': [831], '82:': [833], '99-112Crossref': [834], '(94)': [837], 'essential': [841], 'hemodynamics': [850], 'was': [851, 1082, 1967, 1976, 1989, 2215, 2420, 2464, 2517, 2647, 2657, 2699, 2733, 2751, 2765, 2917, 2954, 2963, 2986, 3000, 3026, 3083, 3093, 3102, 3162, 3215, 3306, 3314, 3368, 3405, 3487, 3500, 3535, 3547, 3566, 3575, 3940, 4142], 'underscored': [852], 'recently': [853], 'identification': [856, 1310], 'disorder,': [860], 'Barth’s': [861], 'syndrome,': [862, 985], 'mutations': [866], 'X-linked': [869, 979, 1022], 'gene': [870], '(Xq28)': [871], 'induce': [872], 'altered': [873, 1110, 1780, 2597], 'metabolism,': [875], 'resulting': [876, 1955, 3522], 'depletion': [879, 1105, 1775, 2592], 'changes,': [883], 'thereby': [884], 'precipitating': [885], 'dysfunction': [887, 1127], 'striking': [890], 'cardiomyopathy': [891], 'neutropenia': [893, 983, 1026], '(8Vreken': [894], 'P.': [895, 962], 'Valianpour': [896, 1010, 1043, 1280], 'F.': [897, 956, 967, 1011, 1044, 1284], 'Nijtmans': [898], 'L.G.': [899], 'Grivell': [900], 'L.A.': [901], 'Plecko': [902, 968], 'Wanders': [904, 957, 1020, 1051, 1285], 'R.J.': [905, 958, 1021, 1052, 1286], 'Barth': [906, 915, 944, 974, 1066, 1287, 1312, 1349], 'P.G.': [907, 975, 1009, 1288], 'Defective': [908], 'phosphatidylglycerol': [913], 'syndrome.Biochem.': [916], 'Commun.': [919], '279:': [921], '378-382Crossref': [922], '(310)': [925], '9Schlame': [928], 'Towbin': [930], 'J.A.': [931], 'Heerdt': [932], 'P.M.': [933], 'Jehle': [934], 'R.': [935, 971], 'DiMauro': [936], 'S.': [937, 1046], 'Blanck': [938], 'T.J.': [939], 'Deficiency': [940], 'tetralinoleoyl-cardiolipin': [942], 'syndrome.Ann.': [945], 'Neurol.': [946], '51:': [948, 1070], '634-637Crossref': [949], '(225)': [952], '10Valianpour': [955], 'Overmars': [959, 1289], 'H.': [960, 1094, 1290, 1510, 1512, 1764, 2581, 2616, 2618, 2778, 2780, 2870, 3225, 3227], 'Vreken': [961], 'Van': [963], 'Gennip': [964, 1292], 'A.H.': [965, 1293], 'Baas': [966], 'Santer': [970], 'Becker': [972], 'K.': [973, 1096, 1766, 2583], 'deficiency': [977], 'cardioskeletal': [980, 1023], 'myopathy': [981, 1024], '(Barth': [984, 1027], 'MIM': [986], '302060):': [987], 'study': [989, 1297, 2771], 'cultured': [991], 'skin': [992], 'fibroblasts.J.': [993], 'Pediatr.': [994], '141:': [996], '729-733Abstract': [997], '(89)': [1005], '11Barth': [1008], 'Bowen': [1012], 'V.M.': [1013], 'Lam': [1014], 'Duran': [1016], 'Vaz': [1018, 1047], 'F.M.': [1019, 1048], 'syndrome):': [1028], 'update.Am.': [1030], 'Med.': [1032], 'Genet.': [1033], '126:': [1035], '349-354Crossref': [1036], '(231)': [1038], '12Gu': [1041], 'Z.': [1042], 'Chen': [1045], 'Hakkaart': [1049], 'G.A.': [1050], 'Aberrant': [1055], 'yeast': [1060], 'taz1': [1061], 'mutant:': [1062], 'model': [1064], 'syndrome.Mol.': [1067], 'Microbiol.': [1068], '149-158Crossref': [1071], '(174)': [1074], 'Recently,': [1077, 1279, 1435], 'demonstrated': [1079, 3649, 4035, 4104], 'substantially': [1083], 'depleted': [1084], 'diabetic': [1086, 1107, 1777, 2594], 'myocardium': [1088, 1108, 1778, 2595], '(13Han': [1089, 1759, 2576], 'X.': [1090, 1467, 1506, 1539, 1573, 1760, 2577, 2612, 2774, 2868, 3221, 3684, 3846, 3880], 'Yang': [1091, 1095, 1507, 1761, 1765, 2578, 2582, 2613, 2775, 3222], 'Cheng': [1093, 1509, 1763, 2580, 2615, 2777, 2869, 3224], 'Abendschein': [1097, 1767, 2584], 'D.R.': [1098, 1768, 2585], 'Gross': [1099, 1468, 1513, 1540, 1574, 1769, 2586, 2619, 2781, 2873, 3228, 3685, 3847, 3881], 'R.W.': [1100, 1469, 1514, 1541, 1575, 1770, 2082, 2587, 2620, 2782, 2874, 3229, 3686, 3848, 3882], 'Shotgun': [1101, 1542, 1576, 1595, 1771, 2588, 3849], 'identifies': [1103, 1773, 2590], 'linking': [1109, 1779, 2596], 'substrate': [1111, 1781, 2598], 'utilization': [1112, 1782, 2599], 'dysfunction.Biochemistry.': [1115, 1785, 2602], '44:': [1117, 1493, 1787, 2604], '16684-16694Crossref': [1118, 1788, 2605], '(142)': [1121, 1791, 2608], 'manifest.': [1129], 'importance': [1131, 1152], 'regulating': [1135], 'signaling': [1138], 'bioenergetics': [1141], 'mammalian': [1143], 'becoming': [1146], 'increasingly': [1147], 'appreciated.': [1148], 'Despite': [1149], 'obvious': [1151], 'physiological': [1156], 'mediating': [1162], 'pathological': [1164], 'sequelae': [1165], 'states,': [1168], 'quantitative': [1170], 'analysis': [1171, 1548, 1581, 2120, 2715, 2962, 3108, 3855, 3884], 'cardiolipin,': [1173], 'particularly': [1174], 'at': [1175, 2138, 2185, 2208, 2330, 2430, 2687, 2924, 3095, 3271, 3277, 3472, 3537, 3741, 4106], 'level,': [1179], 'greatly': [1180], 'lags': [1181], 'behind': [1182], 'Historically,': [1189], 'researchers': [1190], 'have': [1191], 'thin-layer': [1193], 'chromatographic': [1194, 1452], 'techniques': [1195], 'HPLC': [1197], 'coupled': [1198], 'various': [1200, 2230], 'detector': [1201], 'devices': [1202], 'content': [1207, 1677, 2088, 2663], '14Teng': [1235], 'J.I.': [1236], 'Smith': [1237], 'L.L.': [1238], 'High-performance': [1239], 'liquid': [1240, 2434], 'chromatography': [1241, 2078], 'cardiolipin.J.': [1243], 'Chromatogr.': [1244], '1985;': [1245], '339:': [1246], '35-44Crossref': [1247], '(18)': [1250], 'approaches,': [1255], 'only': [1260], 'by': [1262, 1302, 1357, 1432, 1482, 1523, 1619, 1638, 1704, 1727, 2075, 2241, 2541, 2629, 2791, 2965, 3002, 3181, 3188, 3238, 3286, 3308, 3464, 3502, 3673, 3900, 4121], 'GC-MS': [1263], 'after': [1264, 1352, 1426, 1649, 2079, 2332, 2342, 2425, 3833, 3947, 4140], 'reactions': [1267], 'and/or': [1268], 'derivatization': [1269], 'procedures,': [1270], 'destroy': [1272], 'important': [1273], 'information': [1275], 'affecting': [1276], 'properties.': [1278], 'colleagues': [1282, 1364], '(15Valianpour': [1283], 'van': [1291], 'Quantitative': [1294, 3883], 'compositional': [1296], 'platelets': [1301], 'spectrometry:': [1306, 1485], 'application': [1307], 'syndrome': [1313, 1350], 'patients.Clin.': [1314], 'Chem.': [1315], '48:': [1317], '1390-1397Crossref': [1318], '(104)': [1321], 'Scholar)': [1323, 1405, 2271, 2805, 3252], 'reported': [1324], '(ESI)-MS': [1327], 'product': [1328, 3141, 3494, 3674], 'ion': [1329, 2352, 2858, 2940, 2961, 2968, 2998, 3020, 3039, 3107, 3114, 3119, 3142, 3205, 3258, 3401, 3439, 3452, 3495, 3499, 3616, 3675, 3794, 3835, 3937, 3950, 4065, 4132], 'quantify': [1340, 1415], 'platelet': [1345], 'patients': [1351], 'separation': [1353, 1427, 1453], 'normal-phase': [1358, 1433], 'HPLC.': [1359, 1434], 'addition,': [1361], 'Sparagna': [1362], '(4Sparagna': [1365], 'singly': [1407, 3716], 'rat': [1420], 'myocardial': [1421, 2091], 'approach': [1439, 1459, 1799], 'globally': [1441], 'analyze': [1442], 'sample': [1450, 2114, 2458, 2516], 'without': [1451, 2727], 'extracts;': [1457], 'now': [1461], 'known': [1462], '(16Han': [1466], 'Global': [1470], 'lipidomes': [1474, 1518, 1554, 2624, 2786, 3233, 3861], 'crude': [1477, 1557, 3864], 'samples': [1481, 1522, 2628, 2666, 2790, 3237, 3595, 3727, 3899], 'ESI': [1483, 2351, 2922, 3617, 4193], 'bridge': [1487], 'lipidomics.J.': [1489], '2003;': [1492], '1071-1079Abstract': [1494], '(710)': [1502], '17Han': [1505, 2611], 'Ye': [1511, 2617, 2779, 3226], 'Towards': [1515, 2621, 2783, 3230], 'fingerprinting': [1516, 2622, 2784, 3231, 3888], 'two-dimensional': [1524, 1705, 2630, 2792, 3200, 3239], 'spectrometry.Anal.': [1528, 2634, 2796, 3243, 3905], 'Biochem.': [1529, 2262, 2563, 2635, 2797, 3244, 3906], '330:': [1531, 2637, 2799, 3246], '317-331Crossref': [1532, 2638, 2800, 3247], '(181)': [1535, 2641, 2803, 3250], '18Han': [1538], 'lipidomics:': [1543, 1577, 3850], 'spectrometric': [1547, 1580, 2119, 3202, 3619, 3854], 'samples.Mass': [1561, 3868], 'Spectrom.': [1562, 3703, 3869], 'Rev.': [1563, 1585, 3870], '24:': [1565, 3872], '367-412Crossref': [1566, 3873], '(927)': [1569, 3876], '19Han': [1572], 'multi-dimensional': [1578], 'lipidomes.Expert': [1584], 'Proteomics.': [1586], '2:': [1588], '253-264Crossref': [1589], '(215)': [1592], 'multistep': [1599], 'process': [1600, 3192], 'multiplexed': [1602], 'extractions,': [1603], 'intrasource': [1604], 'separation,': [1605], 'multidimensional': [1607, 1739], 'spectrometry': [1609, 2994, 3035], 'analysis.': [1612, 1899], 'two-step': [1621], 'procedure.': [1622], 'first': [1625, 2973, 3005, 3045, 3504], 'step,': [1626, 1654], 'abundant': [1628, 1962], 'nonoverlapping': [1630, 1751], 'quantitated': [1637, 2074], 'ratiometric': [1639, 1713, 4122], 'comparisons': [1640], 'preselected': [1643, 1666], 'internal': [1644, 1667, 2497, 2731, 4138, 4183], 'standard': [1645, 1668, 2498, 2732, 4139, 4184], 'deisotoping.': [1650, 3948], 'second': [1653, 1712, 2990, 3030, 3087, 3518], 'determined': [1658, 2668, 3285, 3307, 3576, 3800], 'plus': [1664], 'standards': [1672], 'determine': [1674], 'overlapping': [1682, 1734], 'one': [1686, 4023], 'more': [1688, 1961], 'tandem': [1689, 3033, 3166, 3175, 3570, 3697, 3903], 'traces': [1691], '(each': [1692], 'characterizes': [1695], 'feature': [1698], 'interest)': [1703], 'MS.': [1706], 'step': [1714], 'quantitation,': [1716, 3214], 'extended': [1725, 1824], 'dramatically': [1726], 'eliminating': [1728, 1732], 'background': [1729], 'noise': [1730], 'approach.': [1740], 'Although': [1741], 'technology': [1743], 'has': [1744, 1815, 3360], 'already': [1745], 'been': [1746, 1818], 'estimate': [1749], 'several': [1757], 'occasions': [1758], 'full': [1795], 'power': [1796], 'accurate': [1802, 1981], 'entire': [1812], 'yet': [1817], 'realized.': [1819], 'study,': [1822], '(QqQ)': [1863], 'type]': [1864], 'setting': [1873, 3276, 3648, 3743, 3782], 'spectrometer': [1882, 2846, 3388, 4195], 'QqTOF': [1884, 3386], 'type).': [1885], 'exploiting': [1902], 'taking': [1935], 'advantage': [1936], 'No': [1950], 'evidence': [1951], '“ion': [1953], 'suppression”': [1954], 'presence': [1958], 'solution': [1966, 1975, 2348, 2698, 2916], 'manifest': [1968], 'long': [1970], 'appropriately': [1973], 'diluted': [1974, 2358, 2400, 2701, 2913], 'used.': [1977], 'Synthetic': [2048], '1,1′,2,2′-tetramyristoyl': [2051], '(T14:0': [2053], 'CL)': [2054, 2059, 2501, 4018, 4029, 4232], '1,1′,2,2′-tetraoleoyl': [2056], '(T18:1': [2058], 'purchased': [2061, 2375], 'Avanti': [2063], 'Polar': [2064], 'Lipids,': [2065], 'Inc.': [2066], '(Alabaster,': [2067], 'AL).': [2068], 'Both': [2069], 'capillary': [2076], 'gas': [2077, 2100, 3091, 3532], 'methanolysis': [2080], '(20Gross': [2081], 'High': [2083], 'plasmalogen': [2084], 'arachidonic': [2086], 'canine': [2090], 'sarcolemma:': [2092], 'fast': [2094], 'atom': [2095], 'bombardment': [2096], 'spectroscopic': [2098, 2102], 'chromatography-mass': [2101], 'characterization.Biochemistry.': [2103], '1984;': [2104], '23:': [2105], '158-165Crossref': [2106], '(237)': [2109], 'Solvents': [2112], 'preparation': [2115], 'obtained': [2122, 2149], 'Burdick': [2124], 'Jackson': [2126, 2378], '(Honeywell': [2127], 'International,': [2128], 'Inc.,': [2129], 'Muskegon,': [2130], 'MI).': [2131], 'All': [2132, 2224, 3169, 3457], 'reagents': [2135], 'least': [2139, 4107], 'analytical': [2140], 'grade': [2141, 2145], 'best': [2144, 4178], 'available': [2146, 3760], 'Fisher': [2152], 'Scientific': [2153], '(Pittsburgh,': [2154], 'PA)': [2155], 'Sigma-Aldrich': [2157], 'Chemical': [2158], 'Co.': [2159], '(St.': [2160], 'Louis,': [2161], 'MO),': [2162], 'indicated.': [2165, 2911], 'Individual': [2166], 'stock': [2167, 2219, 2355], 'solutions': [2168, 2188, 2220, 2228, 2705], 'T14:0': [2170, 2203, 2233, 2500, 2511, 2816, 3625, 3662, 3822, 3945, 3957, 4017, 4028, 4073, 4231], 'CL': [2171, 2174, 2204, 2207, 2234, 2237, 2512, 2817, 2820, 3626, 3629, 3663, 3666, 3823, 3826, 3936, 3946, 3955, 3958, 4015, 4071, 4074], 'T18:1': [2173, 2206, 2236, 2819, 3628, 3665, 3825, 3935, 3954, 4014, 4070], 'chloroform-methanol': [2176, 2320, 2364, 2477, 2673], '(1:1,': [2177, 2321, 2365, 2478, 2674], 'v/v)': [2178, 2322, 2479], 'prepared': [2180, 2216, 2327, 2735], 'stored': [2182, 2329, 2686], 'under': [2183, 2284, 2309, 3730, 3963], 'nitrogen': [2184, 2286, 2311], '−20°C.': [2186], 'brought': [2190], 'room': [2192], 'temperature': [2193, 2432], 'just': [2194, 2711], 'before': [2195, 2493, 2712, 2831], 'use.': [2196], 'One': [2197], 'mixture': [2198], 'ratio': [2201, 3984, 4056, 4207, 4239], 'total': [2210, 2256, 2557, 2760, 3973], 'concentration': [2211, 2651, 2756, 3574, 3983, 4011, 4021, 4040, 4077, 4179, 4226], '100': [2213, 2653], 'nmol/μl': [2214], 'gas-tight': [2222], 'syringes.': [2223], 'mixed': [2227, 2824], 'ratios': [2231, 4000, 4003, 4008, 4012, 4050, 4068, 4085, 4221], 'extracted': [2239, 2537], 'twice': [2240], 'modified': [2243, 2543], 'Bligh': [2244, 2546], 'Dyer': [2246, 2250, 2548, 2551], 'technique': [2247], '(21Bligh': [2248, 2549], 'E.G.': [2249, 2550], 'W.J.': [2251, 2552], 'A': [2252, 2457, 2553], 'rapid': [2253, 2554], 'method': [2254, 2544, 2555], 'extraction': [2258, 2559], 'purification.Can.': [2260, 2561], 'Physiol.': [2263, 2564], '1959;': [2264, 2565], '37:': [2265, 2566], '911-917Crossref': [2266, 2567], '(43132)': [2269, 2570], '10': [2273, 3634, 4045], 'mM': [2274, 2485], 'LiCl': [2275, 2486], 'aqueous': [2278], 'layer.': [2279], 'dried': [2283, 2308, 2314, 2422], 'stream,': [2287], 'dissolved': [2288], 'chloroform,': [2290], 'filtered': [2291], '0.2': [2293], 'μm': [2294], 'Gelman': [2295], 'acrodisc': [2296], 'CR': [2297], 'polytetrafluoroethylene': [2298], '(PTFE)': [2299], 'syringe': [2300, 2933, 3470], 'filters': [2301], '(Gelman': [2302], 'Science,': [2303], 'Ann': [2304], 'Arbor,': [2305], 'MI),': [2306], 'stream.': [2312], 'mixtures': [2316, 2356, 2814, 3623, 3820, 3931, 3959], 'resuspended': [2318], 'reconstitute': [2324], 'originally': [2326], 'concentration,': [2328], '−20°C': [2331, 2688], 'gently': [2333], 'flushing': [2334], 'nitrogen,': [2336, 2683], 'within': [2339, 2693, 3830, 4059], '1': [2340, 2694, 3481, 3916, 4058], 'week': [2341], 'preparation.': [2343], 'Before': [2344], 'infusion': [2345, 2713, 2834, 3466], 'source,': [2353], 'desired': [2361], 'concentrations': [2362, 3927, 3974], 'v/v).': [2366, 2675], 'Male': [2367], 'mice': [2368], '(C57BL/6,': [2369], '4': [2370, 2474, 2929, 3152], 'months': [2371], 'age)': [2373], 'Laboratory': [2379], '(Bar': [2380], 'Harbor,': [2381], 'ME).': [2382], 'tissues,': [2384], 'muscle,': [2390], 'dissected': [2395], 'quickly': [2396, 2421], 'perfused': [2398], '(10-fold)': [2401], 'phosphate-buffered': [2402], 'saline.': [2403], 'Extraneous': [2404], 'tissue': [2405, 2463], 'fat': [2407], 'removed': [2409], 'liver': [2412, 2726], 'heart.': [2414], 'Each': [2415, 2644, 2696], 'collected': [2418], 'tissues': [2419], 'Kimwipes': [2424], 'perfusion': [2426], 'immediately': [2428], 'freeze-clamped': [2429], 'nitrogen.': [2435], 'Wafers': [2436], 'pulverized': [2438, 2744], 'fine': [2441, 2455], 'powder': [2442, 2745], 'stainless-steel': [2445], 'mortar': [2446], 'pestle.': [2448], 'Protein': [2449, 3573], 'assays': [2450], 'performed': [2452, 2841, 2964, 2987, 3001, 3027, 3084, 3383, 3962], 'powder.': [2456], '(∼10': [2459], 'mg)': [2460], 'weighed': [2465], 'disposable': [2468], 'glass': [2469], 'culture': [2470], 'test': [2471, 2491], 'tube,': [2472], 'ml': [2475, 2482], '1.8': [2481], '50': [2484, 2740], 'added': [2488, 2513], 'tube': [2492], 'addition': [2494, 2729], 'amount': [2509], '3.0': [2518], 'nmol/mg': [2519], 'muscle': [2527, 2710], 'samples,': [2528], 'based': [2529, 2658, 2767], 'assay': [2533, 3582], 'result.': [2534], 'Lipids': [2535], 'then': [2539], 'back-extracted': [2540], 'described': [2574, 2737, 3218, 3681, 3843], 'previously': [2575, 3219, 3682, 3844], 'extract': [2646, 2723, 2750, 2830, 2915], 'reconstituted': [2648, 2752], 'μl/mg': [2654], '(which': [2656, 2902], 'original': [2661], 'assays)': [2671], 'finally': [2680], 'flushed': [2681], 'capped,': [2684], 'ESI-MS': [2690, 2838, 3379, 3458, 3951], '(typically': [2691], 'analyzed': [2692, 2936, 3525, 3729], 'week).': [2695], 'further': [2700], '∼100-fold': [2702], 'An': [2720], 'additional': [2721], 'also': [2734, 3382, 3961], 'above': [2738], 'mg': [2741], 'liver.': [2748], 'final': [2755], '260': [2758], 'nmol': [2759], 'lipids/mg': [2761], 'protein/100': [2762], 'μl,': [2763], 'facilitated': [2766], 'our': [2769], '(17Han': [2773, 3220], 'assay.': [2809], 'Different': [2810], 'amounts': [2811, 3691], 'equimolar': [2813, 3622, 3819, 3930], 'indicated': [2822], 'part': [2826], 'dilution': [2832], 'solution.': [2837], 'QqQ': [2844, 3269, 4192], '(ThermoElectron': [2847], 'TSQ': [2848], 'Quantum': [2849], 'Ultra,': [2850], 'San': [2851], 'Jose,': [2852], 'CA)': [2853], 'equipped': [2854, 3397], 'source': [2859, 2923, 3440], 'operated': [2861, 3193, 3406], 'Xcalibur': [2864, 3195], 'software': [2865, 3298], 'system': [2866], '(22Han': [2867], 'Mancuso': [2871], 'D.J.': [2872], 'Caloric': [2875], 'restriction': [2876], 'depletion,': [2880], 'triacylglycerol': [2884], 'accumulation': [2885], 'murine': [2887], 'myocardium.Biochemistry.': [2888], '43:': [2890], '15584-15594Crossref': [2891], '(64)': [2894], 'peak': [2900, 3206, 3210, 3259, 3279, 3348, 3350, 3357, 3373, 3745, 3784, 3795, 3938, 4006, 4066, 4126], 'width': [2901, 3280, 3746, 3785], 'related': [2904], 'resolution)': [2907], 'varied': [2909, 3103], 'infused': [2918], 'flow': [2926, 3474], 'rate': [2927, 3475], 'μl/min': [2930], 'pump': [2934, 3471], 'negative': [2939, 3038], 'mode.': [2941], 'Typically,': [2942, 3150, 3479, 3554], '2': [2944, 3450, 3455, 3556], 'min': [2945, 3153, 3482, 3557], 'period': [2946, 3154, 3483, 3558], 'signal': [2948, 3156, 3485, 3560], 'averaging': [2949, 3157, 3486, 3561], 'profile': [2952, 3160, 3564], 'mode': [2953, 2999, 3161, 3565], 'MS': [2958, 3167, 3172, 3176, 3571], 'spectrum.': [2959, 3168, 3492, 3572], 'Product': [2960], 'selecting': [2966], 'interest': [2970, 3012, 3022], 'analyzing': [2976], 'fragments': [2978, 3523], 'third': [2981, 3016, 3047], 'quadruple': [2982, 3017], 'while': [2983, 3023, 3080], 'collision': [2984, 3024, 3090, 3100, 3448, 3531, 3542], 'activation': [2985, 3025, 3082], 'quadrupole.': [2991, 3031, 3088], 'Tandem': [2992], 'precursor': [2997, 3106, 3118, 3498], 'scanning': [3003], 'monitoring': [3014], 'For': [3032, 3316, 3493], 'mode,': [3042], 'both': [3043, 3834], 'quadrupoles': [3048], 'coordinately': [3050], 'scanned': [3051], 'difference': [3055], 'loss)': [3058], 'corresponding': [3059, 3377, 3653, 3713], 'ketene': [3066], '(representing': [3067], 'building': [3069], 'block': [3070], 'species)': [3074], 'collisional': [3081], 'pressure': [3092, 3534], 'set': [3094, 3536], '1.0': [3096, 3538], 'mTorr,': [3097, 3539], 'energy': [3101, 3543], 'follows:': [3105], 'glycerophosphate': [3111], 'derivative': [3112], '(precursor': [3113], '153.1),': [3115], '35': [3116], 'eV;': [3117, 3129, 3139], 'variety': [3123, 3135], 'carboxylates,': [3127], '28': [3128, 3148], 'ketenes,': [3137], '22': [3138], 'ions,': [3147], 'eV.': [3149], 'spectra': [3173, 3177, 3921], 'automatically': [3179], 'acquired': [3180, 3924], 'customized': [3183], 'sequence': [3184], 'subroutine': [3185], 'smoothed': [3187], 'Gaussian': [3190, 3290, 3303, 3344], 'peak-fitting': [3191], 'software.': [3196, 3411], 'Data': [3197, 3592], 'processing': [3198], 'analyses,': [3203, 3496], 'selection,': [3207], 'data': [3208, 3604], 'transferring,': [3209], 'intensity': [3211, 3374, 3939, 4007, 4067, 4127], 'comparison,': [3212], 'conducted': [3216, 3463], 'MicroSoft': [3254], 'Excel': [3255], 'macros.': [3256], 'intensities': [3260, 3796, 3810], '0.7': [3282, 3511, 3747, 3786], 'Th)': [3283], 'deconvolution': [3287, 3803], 'Origin': [3294], '7.0': [3295], 'nonlinear': [3296], 'least-squares-fitting': [3297], '(www.OriginLab.com).': [3299], 'number': [3301], 'adding': [3309], 'Gaussians': [3310], 'until': [3311], 'residual': [3313], 'structureless.': [3315], 'example,': [3317], 'two-feature': [3319], 'curve': [3320, 3335], 'peaks': [3323, 3652, 3836], 'heavily': [3326], 'overlapped': [3327], 'spectrum)': [3328], 'generally': [3329], 'requires': [3330], 'Gaussians,': [3332, 3338], 'three-feature': [3334], 'needs': [3336], 'etc.': [3339], 'fitting': [3341], 'procedure': [3342], 'yielded': [3343], 'features': [3345], 'fitted': [3347, 3356], 'intensities,': [3349], 'positions,': [3351], 'full-width-at-half-maximums.': [3354], 'intensity,': [3358], 'subtracted': [3361], 'contributions': [3363], 'neighbor': [3366], 'peaks,': [3367], 'attributed': [3369], 'real': [3372], 'm/z.': [3378], '(MDS': [3389], 'Sciex': [3390], 'QStar': [3391], 'XL;': [3392], 'Applied': [3393], 'Biosystems,': [3394], 'Concord,': [3395], 'Canada)': [3396], 'source.': [3402], 'Analyst': [3408], 'QS': [3409], '1.1': [3410], 'following': [3413], 'instrumental': [3414], 'used:': [3417], 'spray': [3418], 'voltage,': [3419], '−4,500': [3420], 'V;': [3421, 3425, 3429, 3434], 'declustering': [3422, 3430], 'potential,': [3423, 3427], '−60': [3424], 'focusing': [3426, 3435], '−265': [3428], 'potential': [3431], '2,': [3432], '−15': [3433], 'rod': [3436], 'offset,': [3437], '−15;': [3438], 'gas,': [3441, 3445, 3449], 'scale': [3442, 3446], '2;': [3443], 'curtain': [3444], '20;': [3447], 'mTorr;': [3451], 'release': [3453], 'delay,': [3454], 'ms.': [3456], 'direct': [3465], 'Harvard': [3469], '6': [3477], 'μl/min.': [3478], 'TOF-MS': [3491], 'selected': [3501, 4137], 'window': [3509], 'Th,': [3512], 'collision-induced': [3513], 'dissociation': [3514], 'occurred': [3515], 'quadrupole,': [3519], 'analyzer.': [3529], '(nitrogen)': [3533], '40': [3545], 'eV': [3546], 'bicinchoninic': [3579], 'kit': [3583], '(Pierce,': [3584], 'Rockford,': [3585], 'IL)': [3586], 'BSA': [3588], 'standard.': [3591], 'normalized': [3597, 3941, 3999, 4049, 4220], 'content,': [3601], 'presented': [3606], 'means': [3608], '±': [3609], 'SD': [3610], 'separate': [3613], 'animals.': [3614], 'Negative': [3615, 3949], 'ranging': [3630], '0.01': [3632, 4043], 'pmol/μl': [3635, 4201], 'QqQ-type': [3641, 3739, 3763], 'intense': [3651], 'deprotonated,': [3655, 3715], '(Fig.': [3667, 3788, 3805, 4062, 4100, 4175, 4216], '1).': [3668], 'confirmed': [3672], '(spectra': [3677], 'shown),': [3679], '(23Han': [3683], 'Structural': [3687], 'determination': [3688], 'picomole': [3690], 'via': [3694], 'Am.': [3700], 'Soc.': [3701], 'Mass': [3702], '1995;': [3704], '6:': [3705], '1202-1210Crossref': [3706], '(258)': [3709], 'Peaks': [3712], 'minimal': [3722], '(data': [3723], 'shown)': [3725], 'when': [3726], 'experimental': [3732, 3831, 3965, 4060], 'conditions.': [3733], 'Th': [3748, 3787], 'unit': [3750], 'resolution.': [3751], 'level': [3754], 'many': [3762], 'spectrometers.': [3765], '13C': [3767], 'isotopomers': [3768], 'cannot': [3776], 'completely': [3778], 'resolved': [3779], '1,': [3789, 3806, 4241], 'inset': [3790, 3807], 'A).': [3791, 3808], 'had': [3797], 'program': [3804], 'paired': [3813], 'essentially': [3828], 'equal': [3829, 4052], 'errors': [3832], 'deconvoluted': [3838], 'subsequently': [3840], 'deisotoped,': [3841], '(18Han': [3845], '24Han': [3879], 'triacylglyceride': [3890], '2001;': [3907], '295:': [3908], '88-100Crossref': [3909], '(299)': [3912], 'Figure': [3915, 3993], 'shows': [3917], 'examples': [3918], 'different': [3926], 'conditions': [3966], 'much': [3969, 3980], 'wider': [3970, 3981], '0.005–100.0': [3976], 'pmol/μl)': [3977], 'molar': [3982, 4010, 4084, 4206], '0.065–26.0)': [3986], 'than': [3987, 4236], 'shown': [3989], 'Fig.': [3991], '1.': [3992, 4164], '2Ashows': [3994], 'plot': [3996], 'versus': [4019], 'mixtures.': [4032], 'that,': [4036], '1,000-fold': [4039, 4109], 'pmol/μl,': [4046], 'averaged,': [4048, 4219], 'theoretical': [4055, 4161, 4238], 'error': [4061], '2).': [4063], 'region': [4078], 'well': [4080], 'correlated': [4081], 'mixtures,': [4088], 'slope': [4091, 4155, 4162], '0.962': [4093], 'correlation': [4096, 4154], 'coefficient': [4097], '0.9942': [4099], '2B).': [4101], 'comparison': [4123], 'deisotoping': [4141], 'possible.': [4143], '∼5%,': [4149], 'according': [4150], 'deviated': [4158], 'low-end': [4166], 'limitation': [4167], '∼10': [4173], 'fmol/μl': [4174, 4230], '2A).': [4176, 4217], 'between': [4197], '0.02': [4198], '7': [4200], 'broad': [4205], '0.065–26.0': [4209], 'examined)': [4211], '<10': [4229], 'significantly': [4234], 'less': [4235]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2129585784', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 15}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 12}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2024-12-08T05:54:41.026899', 'created_date': '2016-06-24'}