Publication Information

{'id': 'https://openalex.org/W2129114790', 'doi': 'https://doi.org/10.1074/jbc.m202158200', 'title': 'Brain-derived Neurotrophic Factor Regulates Surface Expression of α-Amino-3-hydroxy-5-methyl-4-isoxazoleproprionic Acid Receptors by Enhancing the N-Ethylmaleimide-sensitive Factor/GluR2 Interaction in Developing Neocortical Neurons', 'display_name': 'Brain-derived Neurotrophic Factor Regulates Surface Expression of α-Amino-3-hydroxy-5-methyl-4-isoxazoleproprionic Acid Receptors by Enhancing the N-Ethylmaleimide-sensitive Factor/GluR2 Interaction in Developing Neocortical Neurons', 'publication_year': 2002, 'publication_date': '2002-10-01', 'ids': {'openalex': 'https://openalex.org/W2129114790', 'doi': 'https://doi.org/10.1074/jbc.m202158200', 'mag': '2129114790', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12130635'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m202158200', 'pdf_url': 'http://www.jbc.org/article/S0021925819722029/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925819722029/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5003866984', 'display_name': 'Mako Narisawa‐Saito', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mako Narisawa-Saito', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020448212', 'display_name': 'Yuriko Iwakura', 'orcid': 'https://orcid.org/0000-0001-5379-8405'}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuriko Iwakura', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103417502', 'display_name': 'Meiko Kawamura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Meiko Kawamura', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100858013', 'display_name': 'Kazuaki Araki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuaki Araki', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109861618', 'display_name': 'Shunji Kozaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I15807432', 'display_name': 'Osaka Prefecture University', 'ror': 'https://ror.org/02cf1je33', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I15807432']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shunji Kozaki', 'raw_affiliation_strings': ['Department of Veterinary Science, College of Agriculture, Sakai, Osaka 599-8531, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Veterinary Science, College of Agriculture, Sakai, Osaka 599-8531, Japan', 'institution_ids': ['https://openalex.org/I15807432']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047809277', 'display_name': 'Nobuyuki Takei', 'orcid': 'https://orcid.org/0000-0002-6122-939X'}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Nobuyuki Takei', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061069554', 'display_name': 'Hiroyuki Nawa', 'orcid': 'https://orcid.org/0000-0002-7986-8229'}, 'institutions': [{'id': 'https://openalex.org/I71395657', 'display_name': 'Niigata University', 'ror': 'https://ror.org/04ww21r56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I71395657']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroyuki Nawa', 'raw_affiliation_strings': ['Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Neurobiology, Brain Research Institute, Niigata University, Niigata 951-8585 and the', 'institution_ids': ['https://openalex.org/I71395657']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 1.896, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 96, 'citation_normalized_percentile': {'value': 0.999838, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '277', 'issue': '43', 'first_page': '40901', 'last_page': '40910'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10483', 'display_name': 'Nerve injury and regeneration', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10608', 'display_name': 'Neurogenesis and neuroplasticity mechanisms', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hek-293-cells', 'display_name': 'HEK 293 cells', 'score': 0.6565727}], 'concepts': [{'id': 'https://openalex.org/C160268369', 'wikidata': 'https://www.wikidata.org/wiki/Q295251', 'display_name': 'AMPA receptor', 'level': 4, 'score': 0.8536774}, {'id': 'https://openalex.org/C174510640', 'wikidata': 'https://www.wikidata.org/wiki/Q489618', 'display_name': 'HEK 293 cells', 'level': 3, 'score': 0.6565727}, {'id': 'https://openalex.org/C97124661', 'wikidata': 'https://www.wikidata.org/wiki/Q14897782', 'display_name': 'Tropomyosin receptor kinase B', 'level': 4, 'score': 0.5858018}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.5205953}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5118124}, {'id': 'https://openalex.org/C160539049', 'wikidata': 'https://www.wikidata.org/wiki/Q3064187', 'display_name': 'Neurotrophic factors', 'level': 3, 'score': 0.47574803}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.46603033}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4465475}, {'id': 'https://openalex.org/C2778790584', 'wikidata': 'https://www.wikidata.org/wiki/Q123045', 'display_name': 'Brain-derived neurotrophic factor', 'level': 4, 'score': 0.41955227}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41697934}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4114741}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.27588296}], 'mesh': [{'descriptor_ui': 'D019208', 'descriptor_name': 'Brain-Derived Neurotrophic Factor', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019579', 'descriptor_name': 'Neocortex', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018091', 'descriptor_name': 'Receptors, AMPA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D033921', 'descriptor_name': 'Vesicular Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019208', 'descriptor_name': 'Brain-Derived Neurotrophic Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005089', 'descriptor_name': 'Exocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052066', 'descriptor_name': 'N-Ethylmaleimide-Sensitive Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019579', 'descriptor_name': 'Neocortex', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D019579', 'descriptor_name': 'Neocortex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018091', 'descriptor_name': 'Receptors, AMPA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m202158200', 'pdf_url': 'http://www.jbc.org/article/S0021925819722029/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12130635', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m202158200', 'pdf_url': 'http://www.jbc.org/article/S0021925819722029/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 58, 'referenced_works': ['https://openalex.org/W1505414983', 'https://openalex.org/W1511174464', 'https://openalex.org/W1550107279', 'https://openalex.org/W1561089492', 'https://openalex.org/W1665109416', 'https://openalex.org/W1725524769', 'https://openalex.org/W1928374558', 'https://openalex.org/W1965982903', 'https://openalex.org/W1969292775', 'https://openalex.org/W1970235440', 'https://openalex.org/W1971263143', 'https://openalex.org/W1973586624', 'https://openalex.org/W1979305117', 'https://openalex.org/W1979586675', 'https://openalex.org/W1980705587', 'https://openalex.org/W1981808553', 'https://openalex.org/W1984929819', 'https://openalex.org/W1989115458', 'https://openalex.org/W1990293683', 'https://openalex.org/W1990519579', 'https://openalex.org/W1993049854', 'https://openalex.org/W1997276312', 'https://openalex.org/W2003729768', 'https://openalex.org/W2006108102', 'https://openalex.org/W2010816636', 'https://openalex.org/W2011055552', 'https://openalex.org/W2011965698', 'https://openalex.org/W2012678641', 'https://openalex.org/W2020476760', 'https://openalex.org/W2021228443', 'https://openalex.org/W2021541944', 'https://openalex.org/W2024014699', 'https://openalex.org/W2024352808', 'https://openalex.org/W2025126263', 'https://openalex.org/W2026792513', 'https://openalex.org/W2027436298', 'https://openalex.org/W2030822379', 'https://openalex.org/W2036049494', 'https://openalex.org/W2039959072', 'https://openalex.org/W2043377395', 'https://openalex.org/W2048932608', 'https://openalex.org/W2051378734', 'https://openalex.org/W2054595326', 'https://openalex.org/W2055265981', 'https://openalex.org/W2061756913', 'https://openalex.org/W2063089911', 'https://openalex.org/W2067409878', 'https://openalex.org/W2087444289', 'https://openalex.org/W2094544368', 'https://openalex.org/W2102101257', 'https://openalex.org/W2106414999', 'https://openalex.org/W2138497185', 'https://openalex.org/W2140493425', 'https://openalex.org/W2143514697', 'https://openalex.org/W2148156937', 'https://openalex.org/W2151444391', 'https://openalex.org/W2228284898', 'https://openalex.org/W4321429482'], 'related_works': ['https://openalex.org/W4308531319', 'https://openalex.org/W4255543363', 'https://openalex.org/W3143819467', 'https://openalex.org/W2588481612', 'https://openalex.org/W2159041861', 'https://openalex.org/W2158606610', 'https://openalex.org/W2050857698', 'https://openalex.org/W2023719282', 'https://openalex.org/W1593299502', 'https://openalex.org/W1540981172'], 'abstract_inverted_index': {'In': [0, 236, 544, 714, 857, 1402, 1538, 3194, 3600, 3655, 3906, 3995, 4161], 'hippocampal': [1, 237, 1231, 1354, 1412], 'neurons,': [2, 238, 1413], 'the': [3, 87, 100, 110, 118, 123, 137, 155, 194, 210, 226, 239, 323, 336, 346, 354, 359, 373, 391, 430, 446, 462, 583, 686, 742, 912, 1011, 1217, 1226, 1230, 1309, 1320, 1343, 1405, 1414, 1417, 1539, 1564, 1575, 1579, 1598, 1605, 1615, 1620, 1623, 1746, 1771, 1794, 1814, 1822, 2035, 2077, 2144, 2185, 2230, 2313, 2368, 2399, 2404, 2434, 2445, 2499, 2508, 2528, 2531, 2541, 2544, 2603, 2705, 2717, 2790, 2815, 2852, 2894, 2897, 2912, 2917, 2923, 2929, 2936, 2944, 2948, 2971, 2990, 2996, 3076, 3082, 3087, 3156, 3162, 3196, 3209, 3217, 3228, 3338, 3455, 3549, 3594, 3612, 3621, 3667, 3725, 3737, 3763, 3776, 3785, 3789, 3802, 3809, 3826, 3839, 3847, 3869, 3951, 3958, 3966, 3972, 3996, 4004, 4008, 4019, 4022, 4035, 4040, 4060, 4083, 4095, 4098, 4103, 4116, 4190, 4206, 4214, 4233, 4240, 4252, 4260, 4308, 4331], 'exocytotic': [4, 240, 3225, 3622], 'process': [5, 79, 241, 315, 1523, 1603, 3226], 'of': [6, 41, 89, 103, 126, 139, 144, 149, 157, 175, 212, 222, 229, 242, 277, 325, 339, 362, 375, 380, 385, 393, 411, 448, 458, 465, 532, 550, 558, 579, 614, 683, 688, 693, 712, 720, 725, 738, 867, 975, 994, 1014, 1024, 1104, 1120, 1222, 1229, 1323, 1342, 1416, 1424, 1442, 1534, 1550, 1567, 1586, 1614, 1622, 1635, 2037, 2147, 2170, 2184, 2282, 2315, 2493, 2507, 2543, 2725, 2786, 2887, 2896, 2906, 2928, 2943, 2970, 2989, 2995, 3011, 3023, 3050, 3055, 3071, 3089, 3093, 3121, 3158, 3184, 3227, 3231, 3244, 3337, 3345, 3353, 3356, 3366, 3399, 3454, 3462, 3470, 3473, 3483, 3516, 3551, 3615, 3648, 3670, 3739, 3791, 3805, 3812, 3853, 3953, 3961, 3968, 3998, 4007, 4021, 4029, 4043, 4062, 4078, 4100, 4106, 4129, 4143, 4153, 4165, 4171, 4184, 4198, 4205, 4254, 4304], 'α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic': [7, 243, 490, 998], 'acid': [8, 244, 999, 2140], '(AMPA)-type': [9, 245], 'glutamate': [10, 69, 246, 305, 739, 827, 3927, 3954, 3970, 3979], 'receptors': [11, 43, 231, 247, 279, 467, 828, 1224, 1325, 1410, 1552, 2932, 2946, 2973, 2998, 3160, 3187, 3222, 3617, 3672, 3955, 3980, 4024, 4072], 'is': [12, 248, 862, 918, 1312, 1497, 1627, 3641, 3923], 'known': [13, 249, 1824, 3098, 3642, 3924], 'to': [14, 191, 193, 199, 250, 427, 429, 435, 554, 697, 706, 716, 727, 1022, 1213, 1215, 1315, 1333, 1404, 1597, 1619, 1813, 1825, 1931, 2061, 2091, 2137, 2143, 2166, 2226, 2237, 2289, 2291, 2296, 2465, 2527, 2770, 2802, 2891, 2900, 2911, 2956, 2981, 3019, 3033, 3075, 3099, 3118, 3125, 3178, 3643, 3724, 3883, 3925, 3971, 4048, 4275, 4307], 'depend': [15, 251], 'on': [16, 252, 570, 685, 929, 1526, 1583, 1954, 2250, 2666, 2851, 2935, 2947, 3081, 3161, 3239, 3850, 3872, 4025, 4102, 4232, 4256], 'activation': [17, 253, 3952], 'ofN-methyl-d-aspartate': [18, 254, 825], 'channels': [19, 255], 'and': [20, 64, 83, 177, 256, 300, 319, 413, 525, 535, 540, 548, 561, 609, 617, 700, 927, 1006, 1019, 1026, 1118, 1220, 1347, 1437, 1530, 1604, 1630, 1646, 1770, 1776, 1797, 1800, 1808, 1868, 1898, 1912, 1934, 1948, 1996, 2040, 2074, 2176, 2212, 2233, 2312, 2398, 2429, 2444, 2468, 2470, 2487, 2540, 2584, 2602, 2662, 2692, 2704, 2728, 2756, 2768, 2807, 2831, 2870, 2893, 2916, 2922, 3013, 3044, 3110, 3188, 3204, 3236, 3361, 3390, 3401, 3478, 3507, 3518, 3557, 3651, 3661, 3752, 3771, 3820, 3881, 3891, 3977, 3987, 4180, 4317, 4326], 'its': [21, 164, 170, 257, 400, 406, 1791, 3554, 3558], 'resultant': [22, 258], 'Ca2+': [23, 82, 259, 318, 1758, 3232, 3552, 3561, 3569, 3627], 'influx': [24, 260], 'from': [25, 261, 741, 920, 2530, 2627, 2812, 2952, 2977, 3363, 3480, 3929], 'extracellular': [26, 262, 3568], 'spaces.': [27, 263], 'Here': [28, 264], 'we': [29, 108, 265, 344, 1542, 1573, 3547, 4046, 4300], 'found': [30, 266, 1543, 4268], 'that': [31, 143, 154, 185, 205, 267, 379, 390, 421, 441, 916, 1119, 1432, 1544, 3065, 3216, 3611, 3797, 3837, 4015, 4170, 4192, 4251, 4269], 'brain-derived': [32, 268, 477, 486], 'neurotrophic': [33, 269, 478, 487, 568, 973], 'factor': [34, 270, 479, 1125], '(BDNF)': [35, 271], 'induced': [36, 272], 'a': [37, 219, 233, 273, 455, 469, 575, 1350, 1527, 1652, 1743, 2062, 2138, 2321, 2334, 2471, 2503, 2518, 2669, 2880, 3020, 3039, 3319, 3334, 3432, 3436, 3451, 4134], 'rapid': [38, 274, 1580, 2299, 3068, 3091, 4332], 'surface': [39, 75, 196, 227, 275, 311, 432, 463, 1584, 2854, 2938, 2950, 3164, 3185, 3242, 3613, 3726, 3841, 3959, 4005, 4041, 4104, 4118, 4126, 4144, 4163, 4203, 4235, 4309, 4333], 'translocation': [40, 54, 101, 138, 156, 276, 290, 337, 374, 392, 1585, 3243, 3614, 3804, 4042, 4052, 4257], 'AMPA': [42, 105, 230, 278, 341, 466, 1223, 1324, 1409, 1418, 1443, 1500, 1551, 1587, 2241, 2248, 2284, 2849, 2931, 2945, 2972, 2997, 3031, 3072, 3078, 3094, 3159, 3186, 3221, 3245, 3360, 3477, 3616, 3671, 3727, 3806, 3842, 3855, 3908, 3962, 4009, 4023, 4044, 4050, 4091, 4208, 4310], 'in': [44, 48, 160, 197, 224, 280, 284, 396, 433, 460, 537, 709, 829, 923, 1319, 1326, 1411, 1421, 1446, 1503, 1553, 1661, 1665, 1750, 1764, 1941, 2005, 2027, 2034, 2343, 2558, 2635, 2709, 2764, 3220, 3329, 3349, 3393, 3406, 3431, 3446, 3466, 3510, 3523, 3597, 3666, 3736, 3766, 3788, 3915, 3957, 3989, 4053, 4125, 4239, 4263, 4279, 4314, 4324], 'an': [45, 281, 924, 2385, 3224, 3833, 4123], 'activity-independent': [46, 282], 'manner': [47, 283, 926], 'developing': [49, 285, 615], 'neocortical': [50, 286, 1447, 1555, 2864, 3034, 3122, 3583, 3860], 'neurons.': [51, 287, 713, 1329, 1556], 'The': [52, 288, 472, 680, 1101, 1205, 1611, 2107, 2182, 2480, 2505, 2678, 2749, 2904, 2967, 2986, 3030, 3212, 3607, 3886, 4141, 4201, 4320], 'receptor': [53, 70, 106, 120, 289, 306, 342, 356, 1001, 1419, 1444, 1501, 1588, 1625, 2850, 3079, 3728, 3843, 3856, 3909, 4010, 4051, 4092, 4108, 4209, 4311], 'became': [55, 291, 3036], 'evident': [56, 292, 3037], 'within': [57, 293], 'hours': [58, 294], 'as': [59, 72, 295, 308, 529, 1112, 1115, 1336, 1561, 1563, 1668, 2255, 2502, 2833, 3822, 3824, 4131, 4167, 4169], 'monitored': [60, 296], 'by': [61, 86, 297, 322, 1338, 1753, 2047, 2065, 2095, 2189, 2367, 2537, 2550, 2773, 2789, 3003, 3016, 3167, 3382, 3499, 3618, 3625, 3818, 3825, 3897, 3983, 4115, 4213], '[3H]AMPA': [62, 298, 2216, 2294, 2857, 2888, 2908, 3024, 3324, 3346, 3367, 3369, 3441, 3463, 3484, 3486, 3598, 3767, 3778, 3786, 3813, 4218, 4229], 'binding': [63, 299, 2295, 2510, 2858, 2895, 2993, 3032, 3325, 3344, 3370, 3442, 3461, 3487, 3787, 3814, 4230], 'was': [65, 84, 301, 320, 1732, 1970, 2029, 2059, 2084, 2187, 2224, 2287, 2318, 2331, 2431, 2463, 2476, 2515, 2535, 2548, 2605, 2664, 2680, 2707, 2751, 2781, 2800, 2819, 2860, 2902, 3001, 3165, 3327, 3347, 3371, 3386, 3444, 3464, 3488, 3503, 3562, 3570, 3815, 4146, 4173, 4211, 4236], 'resistant': [66, 302], 'against': [67, 303, 2125, 2403], 'ionotropic': [68, 304], 'antagonists': [71, 307], 'evidenced': [73, 309, 1337], 'with': [74, 310, 574, 735, 997, 1010, 1108, 1122, 1349, 1493, 1742, 1757, 1785, 1821, 1879, 1905, 1924, 1937, 1972, 1986, 2052, 2071, 2076, 2086, 2099, 2199, 2229, 2235, 2246, 2301, 2308, 2348, 2384, 2433, 2517, 2682, 2722, 2732, 2753, 2760, 2776, 2804, 2824, 2862, 2873, 2883, 3006, 3042, 3170, 3322, 3333, 3351, 3373, 3408, 3439, 3450, 3468, 3490, 3525, 3564, 3572, 3587, 3734, 3864, 3878, 3901, 4075, 4137, 4227], 'biotinylation': [76, 312, 4119], 'assay.': [77, 313, 4120], 'This': [78, 314, 1522, 3794, 4056, 4187], 'required': [80, 316, 863], 'intracellular': [81, 317, 1102, 2134, 2406, 3626, 3645, 3721, 4199], 'inhibited': [85, 321, 3206, 3593], 'blockers': [88, 324, 3400, 3517], 'conventional': [90, 326], 'exocytosis,': [91, 327], 'brefeldin': [92, 328, 1830, 3199, 3259], 'A,': [93, 329, 3106, 3173, 3200], 'botulinum': [94, 330, 1842, 3107, 3201, 3272], 'toxin': [95, 331, 1843, 3108, 3202], 'B,': [96, 332, 3109, 3203], 'andN-ethylmaleimide.': [97, 333], 'To': [98, 334, 2841, 3085, 3719, 3845, 3964, 4033], 'explore': [99, 335, 3720, 4034], 'mechanism': [102, 338, 1529, 1577, 3088, 4038], 'individual': [104, 340, 1616, 3854], 'subunits,': [107, 343, 1016], 'utilized': [109, 345], 'human': [111, 347, 505, 1568, 1727, 4079], 'embryonic': [112, 348, 506, 1569, 1636], 'kidney': [113, 349, 1570], '(HEK)': [114, 350, 1571], '293': [115, 351], 'cells': [116, 162, 352, 398, 1739, 1781, 1921, 2196, 2305, 2342, 2381, 2555, 3903, 4069, 4224, 4242], 'carrying': [117, 353, 1208, 1745, 4070, 4243], 'BDNF': [119, 135, 206, 223, 355, 371, 442, 459, 564, 581, 721, 726, 861, 917, 976, 1434, 1504, 1535, 1545, 1581, 1729, 1815, 1927, 2685, 2844, 2876, 3007, 3043, 3066, 3126, 3154, 3189, 3210, 3588, 3619, 3640, 3735, 3780, 3848, 3898, 3922, 3973, 4001, 4016, 4101, 4121, 4138, 4193, 4255, 4270], 'TrkB.': [121, 357], 'After': [122, 358, 2017, 2298, 2379, 2879, 3153, 3435], 'single': [124, 360], 'transfection': [125, 361], 'GluR2': [127, 140, 150, 158, 178, 213, 363, 376, 386, 394, 414, 449, 1025, 1121, 1346, 2126, 2430, 2495, 2545, 4130, 4149, 4244, 4261], 'cDNA': [128, 131, 364, 367, 1749, 1786, 4088], 'or': [129, 365, 932, 1640, 1664, 1790, 1828, 1904, 1919, 2194, 2828, 2855, 2874, 3112, 3207, 3865, 4065, 4111], 'GluR1': [130, 176, 186, 366, 412, 422, 1015, 1105, 2428, 3890, 4110, 4166, 4325], 'into': [132, 368, 4094], 'HEK/TrkB': [133, 369], 'cells,': [134, 370, 1572, 4097], 'triggered': [136, 372, 3624, 4122], 'but': [141, 168, 377, 404, 4245], 'not': [142, 169, 378, 405, 3379, 3496, 4174, 4246], 'GluR1.': [145, 381, 4247], 'Subsequent': [146, 382], 'mutation': [147, 383], 'analysis': [148, 384, 2780, 2785], 'carboxyl-terminal': [151, 387], 'region': [152, 388, 2511], 'indicated': [153, 389], 'subunit': [159, 395, 1617, 3857, 4093, 4262], 'HEK293': [161, 397, 1738, 2341, 4068, 4318], 'involved': [163, 399, 3956], 'N-ethylmaleimide-sensitive': [165, 401, 502], 'factor-binding': [166, 402], 'domain': [167, 403, 1103, 2135, 2407], 'PDZ-interacting': [171, 407], 'site.': [172, 408], 'Following': [173, 409, 3868], 'co-transfection': [174, 410], 'cDNAs,': [179, 415], 'solid': [180, 416], 'phase': [181, 417], 'cell': [182, 195, 418, 431, 2316, 2813, 2853, 2937, 2949, 3083, 3163, 3241, 3873, 4117, 4202, 4234], 'sorting': [183, 419, 2330], 'revealed': [184, 420], 'subunits': [187, 423, 1002, 1028, 1445, 4210], 'were': [188, 424, 1643, 1659, 1740, 1762, 1774, 1782, 1803, 1819, 1877, 1922, 1984, 2003, 2045, 2069, 2111, 2197, 2244, 2306, 2346, 2382, 2496, 2556, 2590, 2633, 2720, 2729, 2822, 2889, 2909, 2933, 3116, 3378, 3403, 3495, 3520, 3585, 3732, 3862, 3875, 3894, 3912, 3981, 4073, 4113, 4225], 'also': [189, 425, 820, 1313, 1628, 3913], 'able': [190, 426], 'translocate': [192, 428], 'response': [198, 434], 'BDNF.': [200, 436, 3867], 'An': [201, 437, 2279, 2458], 'immunoprecipitation': [202, 438, 2559, 2636, 2710, 2761], 'assay': [203, 439, 2859, 3169, 3326, 3443, 4216], 'confirmed': [204, 440, 2536], 'stimulation': [207, 443, 1533, 2845], 'can': [208, 444, 565, 2846, 4271], 'enhance': [209, 445, 822, 4272], 'interaction': [211, 447, 1311, 1344], 'withN-ethylmaleimide-sensitive': [214, 450], 'factor.': [215, 451, 2809], 'These': [216, 452, 3062, 4012, 4248], 'results': [217, 453, 3063, 4013, 4249], 'reveal': [218, 454, 3064], 'novel': [220, 456], 'role': [221, 457], 'regulating': [225, 461], 'expression': [228, 464, 1453, 1502, 1799, 2542, 4006, 4105, 4145, 4164], 'through': [232, 468], 'GluR2-NSF': [234, 470], 'interaction.': [235, 471], 'neurotrophins,': [473], 'nerve': [474, 921], 'growth': [475], 'factor,': [476], '(BDNF),': [480], '1The': [481], 'abbreviations': [482], 'used': [483, 2464, 2477, 2606], 'are:': [484], 'BDNF,': [485, 2884, 3323, 3440, 4228], 'factor;': [488, 503], 'AMPA,': [489], 'acid;': [491, 520], 'NMDA,': [492], 'N-methyl-d-aspartate;': [493], 'NEM,': [494, 3205], 'N-ethylmaleimide;': [495], 'αCAMKII,': [496], 'α': [497], 'Ca2+/calmodulin-dependent': [498], 'kinase': [499, 510, 1881, 3237, 3658, 3740, 3799, 3828], 'II;': [500], 'NSF,': [501], 'HEK,': [504], 'kidney;': [507], 'PKC,': [508], 'protein': [509, 1106, 1440, 2026, 2041, 2726, 2754, 3374, 3491, 3653, 3657, 3747, 3910, 4127, 4277, 4305, 4322], 'C;': [511], 'aa,': [512], 'amino': [513, 2483, 2489], 'acid(s);': [514], 'FITC,': [515], 'fluorescein': [516], 'isothiocyanate;': [517], 'BAPTA,': [518, 3556], '1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic': [519], 'ATPγS,': [521], 'adenosine': [522], '5′-O-(thiotriphosphate).': [523], 'neurotrophin-3,': [524], 'neurotrophin-4/5,': [526], 'are': [527, 552, 1211, 1426, 3663], 'implicated': [528, 3665], 'important': [530], 'regulators': [531], 'synaptic': [533, 562, 733, 868, 1334, 1499, 4031], 'development': [534, 560, 692], 'plasticity': [536, 869, 1335, 1608], 'both': [538, 3975, 4313], 'central': [539], 'peripheral': [541], 'nervous': [542], 'systems.': [543], 'particular,': [545], 'activity-dependent': [546, 925, 4066], 'synthesis': [547, 4278, 4306], 'release': [549, 740, 3928], 'neurotrophins': [551, 684], 'suggested': [553, 1212, 1314], 'be': [555, 698, 707, 3832], 'key': [556], 'modulators': [557], 'neuronal': [559, 860, 4026], 'plasticity.': [563], 'exert': [566], 'strong': [567], 'activities': [569], 'immature': [571], 'brain': [572], 'neurons': [573, 619, 695, 729, 931, 1232, 1425, 1560, 1658, 2193, 2865, 2901, 3005, 3123, 3332, 3449, 3584, 3731, 3861, 3931, 4281, 4316], 'subchronic': [576], 'time': [577, 2987, 3012], 'scale': [578], 'days.': [580, 1537], 'enhances': [582, 730], 'dendritic': [584], 'growth,': [585], 'induces': [586, 610], 'synaptogenesis': [587], '(1McAllister': [588], 'A.K.': [589], 'Katz': [590], 'L.C.': [591], 'Lo': [592], 'D.C.': [593], 'Neuron.': [594, 772, 891, 1070, 1096, 1173, 1200, 1257, 1374, 1397, 2621], '1997;': [595, 853, 1042, 1151, 1722, 1964, 3946], '18:': [596], '767-778Google': [597], 'Scholar,': [598, 640, 655, 667, 765, 776, 792, 878, 895, 957, 1045, 1074, 1087, 1139, 1154, 1177, 1261, 1274, 1291, 1378, 1468, 1685, 3685, 3702], '2Lom': [599], 'B.': [600, 769, 794, 810, 905, 1057, 1244], 'Cohen-Cory': [601], 'S.': [602, 673, 750, 851, 1047, 1061, 1082, 1170, 1181, 1193, 1234, 1248, 1486, 1703, 1755, 1852, 2612, 3133], 'J.': [603, 631, 635, 644, 659, 674, 759, 813, 1089, 1093, 1162, 1359, 1365, 1457, 1510, 1674, 1720, 1861, 1962, 2152, 2272, 2360, 2413, 2614, 2650, 3142, 3634, 3944, 4292], 'Neurosci.': [604, 636, 675, 788, 814, 986, 1303, 1963, 3714], '1999;': [605, 637, 652, 954, 1084, 1097, 1136, 1375, 1398, 1465, 1488, 1518, 1682, 1705, 2160, 2362, 2421, 2658], '19:': [606], '9928-9938Google': [607], 'Scholar),': [608, 1867, 2163, 2661], 'various': [611, 710, 865, 1109, 1880, 2885, 3009], 'neurochemical': [612], 'phenotypes': [613], 'excitatory': [616, 731, 1328, 4030], 'inhibitory': [618], '(3Xiong': [620], 'H.': [621, 633, 650, 661, 758, 871, 946, 950, 982, 1030, 1130, 1463, 1480, 1516, 1680, 1697, 1719, 1860, 2158, 2265, 2271, 2359, 2419, 2616, 2656, 3141, 3943, 4291], 'Yamada': [622], 'K.': [623, 646, 657, 671, 804, 835, 959, 1459, 1512, 1676, 1711, 1713, 2154, 2267, 2355, 2415, 2652, 3935, 3937, 4287, 4289], 'Han': [624], 'D.': [625, 806, 2618, 3633], 'Nabeshima': [626], 'T.': [627, 648, 748, 882, 903, 965, 1128, 1134, 1461, 1474, 1476, 1478, 1514, 1678, 1691, 1693, 1695, 1850, 2156, 2261, 2417, 2654, 3131], 'Enikolopov': [628], 'G.': [629, 940, 1055, 1242], 'Carnahan': [630, 643, 658, 1456, 1509, 1673, 2151, 2412, 2649], 'Nawa': [632, 649, 660, 945, 1462, 1479, 1515, 1679, 1696, 2157, 2270, 2358, 2418, 2655, 4290], 'Eur.': [634], '11:': [638], '1567-1576Google': [639], '4Narisawa-Saito': [641], 'M.': [642, 669, 756, 771, 938, 963, 1132, 1166, 1298, 1455, 1470, 1508, 1672, 1687, 1715, 1858, 2150, 2172, 2263, 2411, 2648, 3139, 3631, 3709, 3939, 4285], 'Araki': [645, 1458, 1511, 1675, 2153, 2414, 2651], 'Yamaguchi': [647, 1460, 1473, 1513, 1677, 1690, 2155, 2416, 2653], 'Neuroscience.': [651, 1464, 1517, 1681, 2159, 2420, 2657], '88:': [653, 1466, 1519, 1683, 2161, 2422, 2659], '1009-1014Google': [654, 1467, 1520, 1684, 2162, 2423, 2660], '5Mizuno': [656], 'Dev.': [662], 'Biol.': [663, 760, 1862, 2273, 3143, 4293], '1994;': [664], '165:': [665], '243-256Google': [666], '6Sato': [668], 'Suzuki': [670], 'Nakanishi': [672, 1081, 1169], '2001;': [676, 967, 987, 1304, 2275, 3715, 4295], '21:': [677, 1072, 1175, 1202, 1259, 2623], '3797-3805Google': [678], 'Scholar).': [679, 818, 856, 910, 970, 990, 1100, 1204, 1307, 1401, 1491, 1521, 1725, 1967, 2278, 2424, 2625, 3639, 3718, 3949, 4298], 'biological': [681], 'activity': [682, 719, 2994, 4231], 'induction': [687], 'postsynaptic': [689, 694, 823, 933, 1227], 'components': [690], 'and/or': [691], 'needs': [696], 'evaluated,': [699], 'their': [701, 1451, 1798, 3192, 3984], 'underlying': [702, 1578], 'molecular': [703, 1576, 4037], 'mechanisms': [704], 'remain': [705], 'characterized': [708, 1591], 'types': [711, 1423], 'addition': [715, 3352, 3469], 'such': [717, 1114, 1327], 'chronic': [718, 1433, 1532], 'for': [722, 864, 1536, 1787, 1928, 1998, 2023, 2252, 2427, 2478, 2596, 2607, 2686, 2698, 2746, 2867, 3008, 3103, 3589, 4039, 4089, 4148], 'days,': [723], 'application': [724], 'cultured': [728, 1554, 1559, 2863, 3330, 3447, 3582, 3730, 3859, 3930], 'glutamatergic': [732], 'transmission': [734], 'increased': [736, 2951, 2976, 3046, 3181, 3896, 3914, 4003, 4238], 'efficacy': [737], 'presynaptic': [743, 4063], 'neuron': [744], '(7Takei': [745, 1847, 3128], 'N.': [746, 752, 984, 1709, 1848, 1854, 2269, 3129, 3135, 3933, 4283], 'Numakawa': [747, 1849, 3130], 'Kozaki': [749, 1851, 3132], 'Sakai': [751, 1853, 3134], 'Endo': [753, 1716, 1855, 3136, 3940], 'Y.': [754, 1141, 1276, 1717, 1856, 2259, 2357, 3137, 3687, 3941], 'Takahashi': [755, 1714, 1857, 3138, 3938], 'Hatanaka': [757, 1718, 1859, 3140, 3942], 'Chem.': [761, 1863, 2274, 3144, 4294], '1998;': [762, 1071, 1174, 1201, 1258, 1271, 1864, 2622, 3145, 3682], '273:': [763, 1865, 3146], '27620-27624Google': [764, 1866, 3147], '8Schinder': [766], 'A.F.': [767], 'Berninger': [768], 'Poo': [770], '2000;': [773, 789, 815, 1288, 3699], '25:': [774], '151-163Google': [775], '9Jovanovic': [777], 'J.N.': [778], 'Czernik': [779], 'A.J.': [780, 1472, 1689], 'Fienberg': [781], 'A.A.': [782, 1036], 'Greengard': [783], 'P.': [784, 901, 1049, 1147, 1179, 1236], 'Sihra': [785], 'T.S.': [786], 'Nat.': [787, 1301, 3712], '3:': [790], '323-329Google': [791], '10Xu': [793], 'Gottschalk': [795], 'W.': [796], 'Chow': [797], 'A.': [798, 852, 897, 942, 961, 1078, 1156, 1282, 1380, 1487, 1704, 3693], 'Wilson': [799], 'R.I.': [800], 'Schnell': [801], 'E.': [802, 1160, 1367], 'Zang': [803], 'Wang': [805, 902], 'Nicoll': [807], 'R.A.,': [808], 'Lu,': [809], 'Reichardt': [811], 'L.F.': [812, 1265, 3676], '20:': [816], '6888-6897Google': [817], 'Neurotrophins': [819], 'acutely': [821], 'responsiveness': [824], '(NMDA)-type': [826], 'mature': [830], 'synapses': [831], '(11Suen': [832], 'P.C.,': [833], 'Wu,': [834], 'Levine': [836], 'E.S.': [837], 'Mount': [838], 'H.T.,': [839], 'Xu,': [840], 'J.L.': [841], 'Lin': [842], 'S.Y.': [843], 'Black': [844], 'I.B.': [845], 'Proc.': [846, 1481, 1698], 'Natl.': [847, 1482, 1699], 'Acad.': [848, 1483, 1700], 'Sci.': [849, 1484, 1701], 'U.': [850, 1485, 1702], '94:': [854], '8191-8195Google': [855], 'addition,': [858, 3656], 'endogenous': [859, 3969], 'forms': [866], '(12Kang': [870], 'Schuman': [872], 'E.M.': [873], 'Science.': [874, 966, 1287, 3698], '1995;': [875], '267:': [876], '1658-1662Google': [877], '13Patterson': [879], 'S.L.': [880], 'Abel': [881], 'Deuel': [883], 'T.A.': [884, 1195, 1388], 'Martin': [885], 'K.C.': [886], 'Rose': [887], 'J.C.': [888, 1284, 3695], 'Kandel': [889], 'E.R.': [890], '1996;': [892, 907], '16:': [893], '1137-1145Google': [894], '14Figurov': [896], 'Pozzo-Miller': [898], 'L.D.': [899], 'Olafsson': [900], 'Lu': [904], 'Nature.': [906, 1041, 1135, 1150], '381:': [908], '706-709Google': [909], 'However,': [911], 'latest': [913], 'studies': [914], 'demonstrate': [915], 'released': [919], 'terminals': [922], 'act': [928], 'target': [930], 'sites': [934], '(15Griesbeck': [935], 'O.': [936], 'Canossa': [937], 'Campana': [939], 'Gartner': [941], 'Hoener': [943], 'M.C.': [944], 'Kolbeck': [947], 'R.': [948, 1063, 1250, 1286, 1382, 3697], 'Thoenen': [949], 'Microsc.': [951], 'Res.': [952], 'Tech.': [953], '45:': [955], '262-275Google': [956], '16Kohara': [958], 'Kitamura': [960], 'Morishima': [962], 'Tsumoto': [964], '291:': [968], '2419-2423Google': [969], 'Accordingly,': [971], 'anterograde': [972], 'functions': [974], 'have': [977, 1003, 1316, 4267], 'now': [978], 'been': [979, 1004], 'established': [980, 4074], '(17Nawa': [981], 'Takei': [983, 2268], 'Trends': [985], '24:': [988, 1399], '683-684Google': [989], 'A': [991, 1831, 1870], 'large': [992], 'variety': [993], 'molecules': [995], 'interacting': [996, 1206], '(AMPA)': [1000], 'identified': [1005], 'characterized;': [1007], 'SAP97': [1008], 'associates': [1009, 1107], 'COOH': [1012, 2116, 2145], 'termini': [1013], 'whereas': [1017, 3567], 'GRIP/ABP': [1018], 'Pick1': [1020], 'bind': [1021], 'those': [1023], 'GluR3': [1027], '(18Dong': [1029], "O'Brien": [1031, 1960], 'R.J.': [1032, 1067, 1254, 1263, 1961, 3674], 'Fung': [1033], 'E.T.': [1034], 'Lanahan': [1035], 'Worley': [1037], 'P.F.': [1038], 'Huganir': [1039, 1094, 1266, 1958, 2619, 3677], 'R.L.': [1040, 1095, 1267, 1959, 2620, 3678], '386:': [1043], '279-284Google': [1044], '19Srivastava': [1046], 'Osten': [1048, 1235], 'Vilim': [1050, 1184, 1237], 'F.S.': [1051, 1185, 1238], 'Khatri': [1052, 1186, 1239], 'L.': [1053, 1187, 1240, 1363], 'Inman': [1054, 1182, 1241], 'States': [1056, 1190, 1243], 'Daly': [1058, 1245], 'C.': [1059, 1246], 'DeSouza': [1060, 1247], 'Abagyan': [1062, 1249], 'Valtschanoff': [1064, 1251], 'J.G.': [1065, 1252], 'Weinberg': [1066, 1253], 'Ziff': [1068, 1198, 1255], 'E.B.': [1069, 1199, 1256], '581-591Google': [1073, 1260], '20Dev': [1075], 'K.K.': [1076], 'Nishimune': [1077], 'Henley': [1079, 1171, 1372, 1391], 'J.M.': [1080, 1172, 1373, 1392], 'Neuropharmacology.': [1083], '38:': [1085], '635-644Google': [1086], '21Xia': [1088], 'Zhang': [1090], 'X.': [1091], 'Staudinger': [1092], '22:': [1098], '179-187Google': [1099], 'signal': [1110], 'transducers': [1111], 'well,': [1113], 'Gi': [1116], 'protein,': [1117], 'Lyn': [1123], 'andN-ethyl-maleimide-sensitive': [1124], '(NSF)': [1126], '(22Hayashi': [1127], 'Umemori': [1129], 'Mishina': [1131], 'Yamamoto': [1133, 1477, 1694], '397:': [1137], '72-76Google': [1138], '23Wang': [1140], 'Small': [1142], 'D.L.': [1143], 'Stanimirovic': [1144], 'D.B.': [1145], 'Morley': [1146], 'Durkin': [1148], 'J.P.': [1149], '389:': [1152], '502-504Google': [1153], '24Nishimune': [1155], 'Isaac': [1157, 1393], 'J.T.': [1158, 1394], 'Molnar': [1159, 1366], 'Noel': [1161], 'Nash': [1163], 'S.R.': [1164], 'Tagaya': [1165], 'Collingridge': [1167, 1370, 1395], 'G.L.': [1168, 1371, 1396], '87-97Google': [1176], '25Osten': [1178], 'Srivastava': [1180], 'G.J.': [1183], 'Lee': [1188], 'L.M.': [1189], 'B.A.': [1191], 'Einheber': [1192], 'Milner': [1194], 'Hanson': [1196], 'P.I.': [1197], '99-110Google': [1203], 'proteins': [1207, 1983, 2547, 3871, 3893], 'PDZ': [1209], 'domains': [1210], 'cooperate': [1214], 'regulate': [1216], 'dynamics,': [1218], 'targeting,': [1219], 'clustering': [1221], 'at': [1225, 1651, 1979, 1993, 2019, 2031, 2079, 2592, 2599, 2689, 2694, 2701, 2743], 'membrane': [1228, 2064, 2078], '(19Srivastava': [1233], "26O'Brien": [1262], 'Lau': [1264, 3675], 'Curr.': [1268, 3679], 'Opin.': [1269, 3680], 'Neurobiol.': [1270, 3681], '8:': [1272, 3683], '364-369Google': [1273, 3684], '27Hayashi': [1275, 3686], 'Shi': [1277, 3688], 'S.H.': [1278, 3689], 'Esteban': [1279, 3690], 'J.A.': [1280, 3691], 'Piccini': [1281, 3692], 'Poncer': [1283, 3694], 'Malinow': [1285, 3696], '287:': [1289, 3700], '2262-2267Google': [1290, 3701], '28Carroll': [1292, 3703], 'R.C.': [1293, 1300, 3704, 3711], 'Beattie': [1294, 3705], 'E.C.': [1295, 3706], 'von': [1296, 3707], 'Zastrow': [1297, 3708], 'Malenka': [1299, 3710], 'Rev.': [1302, 3713], '2:': [1305, 3716], '315-324Google': [1306, 3717], 'Similarly,': [1308], 'NSF-GluR2': [1310], 'some': [1317, 1817], 'roles': [1318], 'subcellular': [1321, 1548, 1801, 3069, 3668, 3851], 'dynamics': [1322, 1420, 1621, 1802, 3669], 'NSF': [1330, 1348, 2167, 2509], 'might': [1331, 3831], 'contribute': [1332], 'electrophysiological': [1339], 'studies:': [1340], 'Disruption': [1341], 'between': [1345, 1600, 3388, 3505], 'decoy': [1351], 'peptide': [1352, 2141], 'influences': [1353, 4099], 'long': [1355], 'term': [1356], 'depression': [1357], '(29Noel': [1358], 'Ralph': [1360], 'G.S.': [1361], 'Pickard': [1362], 'Williams': [1364], 'Uney': [1368], 'J.B.': [1369], '23:': [1376], '365-376Google': [1377], '30Luthi': [1379], 'Chittajallu': [1381], 'Duprat': [1383], 'F.': [1384], 'Palmer': [1385], 'M.J.': [1386], 'Benke': [1387], 'Kidd': [1389], 'F.L.': [1390], '389-399Google': [1400], 'contrast': [1403], 'above': [1406, 3608, 4036], 'information': [1407], 'about': [1408], 'characteristics': [1415], 'other': [1422, 3827], 'largely': [1427], 'unknown.': [1428], 'We': [1429, 1590, 4266], 'recently': [1430], 'reported': [1431, 1609], 'treatment': [1435, 3127, 3781, 3899], 'increases': [1436], 'maintains': [1438, 3838], 'total': [1439, 2918, 3916, 4321], 'levels': [1441, 3183, 3911, 4020, 4128, 4328], 'cultures': [1448, 1818, 1876, 1918, 2827, 2830, 2892, 3120], 'without': [1449, 2638, 2875, 3866], 'influencing': [1450], 'mRNA': [1452], '(4Narisawa-Saito': [1454, 1507, 1671, 2149, 2410, 2647], '31Narisawa-Saito': [1469, 1686], 'Silva': [1471, 1688], 'Hayashi': [1475, 1692], '96:': [1489, 1706], '2461-2466Google': [1490, 1707], 'Consistent': [1492], 'this': [1494, 1592, 1601, 3090, 3580], 'finding,': [1495], 'there': [1496, 3830], 'impaired': [1498], 'knockout': [1505], 'mice': [1506], 'presumably': [1524, 4058], 'depends': [1525], 'post-translational': [1528], 'requires': [1531], 'present': [1540], 'study,': [1541], 'triggers': [1546, 3067], 'dynamic': [1547], 'movement': [1549], 'Using': [1557], 'primary': [1558, 2109, 3119], 'well': [1562, 3823, 4168], 'heterologous': [1565], 'system': [1566, 2325, 4057], 'explored': [1574], 'effects': [1582, 3398, 3515, 3849, 4253], 'subunits.': [1589, 4011], 'cellular': [1593, 3101, 3917], 'phenomenon,': [1594], 'paying': [1595], 'attention': [1596], 'difference': [1599], 'BDNF-dependent': [1602, 3764, 3803], 'NMDA': [1606], 'receptor-dependent': [1607], 'previously.': [1610], 'potential': [1612, 4302], 'contribution': [1613, 3967, 4303], 'regulation': [1618], 'whole': [1624], 'complexes': [1626], 'examined': [1629], 'discussed.': [1631], 'Whole': [1632], 'cerebral': [1633], 'neocortices': [1634], 'day': [1637, 2631], '18': [1638, 2980], 'rats': [1639, 1642, 2629], 'neonatal': [1641], 'mechanically': [1644], 'dissociated': [1645], 'plated': [1647], 'onto': [1648], 'poly-d-lysine-coated': [1649], 'dishes': [1650], 'low': [1653], 'density': [1654], '(400–600': [1655], 'cells/mm2).': [1656], 'Cortical': [1657], 'grown': [1660, 2866], 'serum-free': [1662], 'condition': [1663], 'serum-containing': [1666], 'medium': [1667, 1765], 'described': [1669, 2256], 'previously': [1670, 2257], 'Scholar,32Takei': [1708], 'Sasaoka': [1710, 3934], 'Inoue': [1712, 3936], 'Neurochem.': [1721, 2361, 3945], '68:': [1723, 3947], '370-375Google': [1724, 3948], 'Purified': [1726], 'recombinant': [1728], '(50': [1730, 2877], 'ng/ml)': [1731], 'added': [1733], '4–5': [1734], 'days': [1735, 2869], 'after': [1736, 3038, 4133], 'plating.': [1737], 'transfected': [1741, 1784], 'vector': [1744], 'mouse': [1747, 2122, 2177, 2388, 2494], 'TrkB': [1748, 4071, 4080], 'pRc/CMV': [1751], '(provided': [1752], 'Dr.': [1754, 2171], 'Koizumi)': [1756], 'phosphate': [1759], 'method.': [1760], 'Cells': [1761, 2002, 2243], 'selected': [1763], 'containing': [1766, 1944, 2204, 2561, 2640, 2712], '400': [1767], 'μg/ml': [1768, 2642, 3258], 'Geneticin,': [1769], 'drug-resistant': [1772], 'colonies': [1773], 'isolated': [1775], 'expanded': [1777], '(HEK-TrkB': [1778], 'cells).': [1779], 'HEK-TrkB': [1780, 1920, 2195, 2554, 4096, 4241, 4264], 'transiently': [1783], 'GluR1,': [1788], 'GluR2,': [1789, 4112], 'derivatives': [1792], 'using': [1793, 1805, 2320, 2333, 2498, 2668, 2783, 3553, 4217], 'lipofection': [1795], 'method,': [1796], 'analyzed': [1804, 3404, 3521], 'Western': [1806, 1999, 2551, 2774, 3884], 'blotting': [1807, 2000, 2552, 2775], 'immunostaining': [1809], 'methods,': [1810], 'respectively.': [1811, 2457], 'Prior': [1812], 'treatment,': [1816, 3870], 'pre-incubated': [1820], 'reagents': [1823, 3097], 'influence': [1826, 2847, 3100], 'exocytosis': [1827, 3104, 3197, 3234], 'endocytosis,': [1829, 3180], '(5': [1832], 'μg/ml;': [1833, 2392, 2441, 2452, 2737], 'Wako': [1834, 1873], 'Chemicals,': [1835], 'Osaka,': [1836], 'Japan),': [1837], 'NEM': [1838], '(1': [1839, 1871], 'mm;': [1840], 'Sigma),': [1841], 'B': [1844], '(100': [1845, 2285], 'nm)': [1846, 2462, 2475], 'bafilomycin': [1869, 3252], 'μm;': [1872], 'Chemicals).': [1874], 'Alternatively,': [1875, 2796], 'supplemented': [1878], 'inhibitors': [1882, 1907, 3238, 3402, 3519, 3985], '(10': [1883, 2408], 'μmU73122': [1884], '(Calbiochem,': [1885], 'San': [1886, 2454], 'Diego,': [1887, 2455], 'CA),': [1888, 2121, 2456], '25': [1889], 'μm': [1890, 1894, 1900, 1914, 2206, 3251, 3359, 3476], 'PD98059': [1891, 3745], '(Calbiochem),': [1892], '1': [1893, 1938, 1945, 1949, 2581, 3028], 'calphostin': [1895, 3749], 'C': [1896, 3650, 3659, 3750, 3760], '(Sigma),': [1897], '0.5': [1899, 2174, 2309, 2570], 'KN93': [1901, 3753, 3772], '(Wako': [1902], 'Chemicals))': [1903], 'translation': [1906, 4273], '(2': [1908], 'ng/ml': [1909, 1926, 2684], 'cycloheximide': [1910], '(Sigma)': [1911], '30': [1913, 1929, 2687], 'anisomycin': [1915], '(Sigma)).': [1916], 'Neocortical': [1917], 'treated': [1923, 2681, 2872, 3863], '100': [1925, 2205, 3358, 3475], 'min': [1930, 1953, 2254, 2598, 2688, 2700], '24': [1932, 3048], 'h': [1933, 3049], 'then': [1935, 2730, 2871, 3014], 'incubated': [1936, 1971, 2075, 2245, 2383, 2731, 3586], 'mmsulfo-NHS-LC-biotin': [1939], '(Pierce)': [1940, 1977], 'phosphate-buffered': [1942], 'saline': [1943], 'mm': [1946, 1950, 2015, 2210, 2563, 2568, 2571, 2579, 2582, 3265, 3282, 3288], 'CaCl2': [1947], 'MgCl2for': [1951], '15': [1952], 'ice': [1955, 2251], '(33Mammen': [1956], 'A.L.': [1957], '17:': [1965], '7351-7358Google': [1966], 'Cell': [1968, 2329, 2588], 'lysate': [1969, 2679], 'ImmunoPure': [1973], 'immobilized': [1974], 'streptavidin-beaded': [1975], 'agarose': [1976], 'overnight': [1978], '4': [1980, 2080, 2600, 2702, 2744, 3426, 3543], '°C.': [1981], 'Biotinylated': [1982], 'eluted': [1985], '2%': [1987, 2012], 'sodium': [1988, 2207, 2586, 2714], 'dodecyl': [1989], 'sulfate': [1990], '(SDS)': [1991], 'buffer': [1992, 2009, 2232, 2560, 2637, 2711], '95': [1994, 2032], '°C': [1995, 2033, 2081, 2691, 2745], 'processed': [1997], 'analysis.': [2001, 2191, 2553], 'lysed': [2004, 2307], 'Laemmli': [2006], 'sample': [2007], 'loading': [2008], '(10%': [2010], 'glycerol,': [2011], 'SDS,': [2013], '65': [2014], 'Tris).': [2016], 'centrifugation': [2018], '10,000': [2020, 2593, 2695], '×': [2021, 2594, 2696], 'g': [2022, 2595, 2697], '10': [2024, 2562, 2597], 'min,': [2025], 'supernatants': [2028, 2719], 'denatured': [2030], 'presence': [2036, 3738, 3790, 3997], '0.5m': [2038], '2-mercaptoethanol': [2039], 'samples': [2042], '(15': [2043], 'μg/lane)': [2044], 'separated': [2046], 'SDS-polyacrylamide': [2048], 'gel': [2049], 'electrophoresis': [2050], '(PAGE)': [2051], '1-mm-thick,': [2053], '8%': [2054, 4152], 'polyacrylamide': [2055], 'slab': [2056], 'gels.': [2057], 'Protein': [2058], 'transferred': [2060], 'nitrocellulose': [2063], 'electrophoresis.': [2066], 'Primary': [2067], 'antibodies': [2068, 2110, 2351, 2646, 2735], 'diluted': [2070, 2234], 'blocking': [2072], 'solution': [2073], 'overnight.': [2082], 'Immunoreactivity': [2083], 'detected': [2085], 'goat': [2087], 'anti-rabbit': [2088, 2371, 2437], 'immunoglobulin': [2089, 2372, 2438, 2449], 'conjugated': [2090], 'peroxidase': [2092], '(1:10,000)': [2093], 'followed': [2094, 2366, 2772, 2788], 'chemiluminescence': [2096], 'reaction': [2097], 'combined': [2098], 'film': [2100], 'exposure': [2101], '(ECL': [2102], 'kit;Amersham': [2103], 'Biosciences,': [2104], 'Tokyo,': [2105, 2327, 2676], 'Japan).': [2106, 2328, 2677], 'following': [2108], 'used:': [2112], 'affinity-purified': [2113, 2131, 2643], 'rabbit': [2114, 2132, 2164, 2400], 'anti-GluR1': [2115, 2349], 'terminus': [2117, 2128, 2146], '(Chemicon': [2118, 2129], 'International,': [2119], 'Temecula,': [2120], 'monoclonal': [2123, 2178, 2389, 2393, 2738], 'antibody': [2124, 2180, 2373, 2390, 2394, 2402, 2439, 2450, 2739], 'NH2': [2127], 'International),': [2130], 'anti-GluR2': [2133, 2386, 2733], '(made': [2136], '50-amino': [2139], 'corresponding': [2142], 'GluR2)': [2148], 'antisera': [2165], '(a': [2168], 'gift': [2169], 'Takahashi,': [2173], 'μg/ml),': [2175], 'pan-cadherin': [2179], '(Sigma).': [2181, 2242], 'immunoreactivity': [2183, 2426], 'bands': [2186], 'quantified': [2188], 'densitometric': [2190], 'Cultured': [2192], 'rinsed': [2198], 'Tris': [2200, 2231, 2303], 'buffer,': [2201, 2304, 2762, 2767], 'pH': [2202, 2565], '7.4,': [2203], 'acetate,': [2208], '2.5': [2209], 'CaCl2,': [2211], '5': [2213, 2641, 2868], 'g/liter': [2214], 'glucose.': [2215], '(1,561': [2217], 'GBq/mmol,': [2218], '37': [2219, 2690], 'MBq/ml,': [2220], 'PerkinElmer': [2221], 'Life': [2222], 'Sciences)': [2223], 'adjusted': [2225], '50': [2227], 'nm': [2228, 2239, 3271], '0': [2236], '800': [2238], 'cold': [2240, 2283, 2302, 3357, 3474], 'these': [2247, 3792, 3999, 4223], 'solutions': [2249], '60': [2253, 2699], '(34Iwakura': [2258], 'Nagano': [2260], 'Kawamura': [2262, 4284], 'Horikawa': [2264], 'Ibaraki': [2266], '276:': [2276, 4296], '40025-40032Google': [2277], 'excess': [2280, 2723, 3354, 3471], 'amount': [2281, 3811], 'μm)': [2286], 'applied': [2288, 2801, 2890, 3117], 'culture': [2290, 2345, 3035, 3350, 3467], 'estimate': [2292], 'nonspecific': [2293], 'cells.': [2297, 4055, 4265, 4319], 'washing': [2300], 'n': [2310, 4155], 'NaOH': [2311], 'radioactivity': [2314], 'lysates': [2317, 2589, 3918], 'counted': [2319], 'LSC-3050': [2322], 'liquid': [2323], 'scintillation': [2324], '(Aloka,': [2326], 'performed': [2332, 2516, 2665, 2782, 2861, 3328, 3445], 'laser': [2335, 2460, 2473], 'scanning': [2336], 'cytometer': [2337], '(LSC2,': [2338], 'Olympus).': [2339], 'Co-transfected': [2340], 'live': [2344], 'immunostained': [2347], 'NH2-terminal': [2350, 2387, 2734], '(30': [2352], 'μg/ml)': [2353], '(35Ibaraki': [2354], 'Otsu': [2356], '73:': [2363], '408-417Google': [2364], 'Scholar)': [2365, 3148], 'FITC-conjugated': [2369], 'secondary': [2370, 2436, 2447], '(Jackson': [2374], 'Laboratories,': [2375], 'Bar': [2376], 'Harbor,': [2377], 'ME).': [2378], 'fixation,': [2380], '(20': [2391], '397,': [2395, 2740], 'Chemicon': [2396, 2741], 'International)': [2397, 2742], 'polyclonal': [2401], 'anti-GluR2/3': [2405], 'μg/m)': [2409], 'Total': [2425], 'visualized': [2432], 'Cy5-labeled': [2435], '(2.5': [2440, 2451], 'Amersham': [2442], 'Biosciences)': [2443], 'R-phycoerythrin-labeled': [2446], 'anti-mouse': [2448], 'PharMingen,': [2453], 'argon': [2459], '(488': [2461], 'excite': [2466], 'FITC': [2467], 'R-phycoerythrin,': [2469], 'helium/neon': [2472], '(633': [2474], 'Cy-5.': [2479], 'COOH-terminal': [2481], 'five': [2482, 2758], 'acids': [2484, 2490], '(aa': [2485, 2491, 2512], '858–862)': [2486], '20': [2488], '843–862)': [2492], 'deleted,': [2497], 'pCI': [2500], 'plasmid': [2501], 'template.': [2504], 'deletion': [2506, 2534], '823–832;': [2513], 'KRMKVAKNAQ)': [2514], 'site-directed': [2519], 'mutagenesis': [2520], 'kit': [2521], '(Clontech,': [2522], 'Palo': [2523], 'Alto,': [2524], 'CA)': [2525], 'according': [2526], 'instructions': [2529], 'manufacturer.': [2532], 'Nucleotide': [2533], 'DNA': [2538], 'sequencing,': [2539], 'mutant': [2546], 'verified': [2549], 'harvested': [2557], 'Tris-HCl,': [2564], '7.5,': [2566], '150': [2567], 'NaCl,': [2569], 'ATPγS': [2572], '(Roche': [2573], 'Molecular': [2574], 'Biochemicals,': [2575], 'Mannheim,': [2576], 'Germany),': [2577], '2': [2578, 2747, 3920, 3993], 'EDTA,': [2580], 'EGTA,': [2583], '1%': [2585, 2713], 'deoxycholate.': [2587, 2715], 'centrifuged': [2591, 2693], '°C,': [2601, 2703], 'supernatant': [2604], 'co-immunoprecipitation': [2608], '(36Song': [2609], 'I.': [2610], 'Kamboj': [2611], 'Xia': [2613], 'Dong': [2615], 'Liao': [2617], '393-400Google': [2624], 'Neocortices': [2626], 'young': [2628], '(postnatal': [2630], '3–4)': [2632], 'homogenized': [2634], 'deoxycholate,': [2639], 'chicken': [2644], 'anti-BDNF': [2645], 'homogenization': [2663], 'ice,': [2667], 'Handy': [2670], 'Sonic': [2671], 'tissue': [2672], 'grinder': [2673], '(Tomy': [2674], 'Inc.,': [2675], '200': [2683], 'pellet': [2706], 'solubilized': [2708], 'All': [2716], 'cleared': [2718], 'pretreated': [2721], 'amounts': [2724, 3355, 3472], 'A-Sepharose': [2727, 2755], '(4': [2736], 'h.': [2748, 3591], 'immunocomplex': [2750], 'precipitated': [2752], 'washed': [2757], 'times': [2759], 'boiled': [2763], '2×': [2765], 'SDS': [2766], 'subjected': [2769, 2910, 3882], 'SDS-PAGE': [2771], 'anti-NSF': [2777], 'antibody.': [2778], 'Statistical': [2779], 'one-way': [2784], 'variance': [2787], 'Bonferroni': [2791], 'test': [2792, 2799, 2818], '(for': [2793], 'multiple': [2794, 2805, 2825], 'factors).': [2795], "Student's": [2797], 't': [2798], 'data': [2803, 2811], 'variables': [2806], 'one': [2808], 'For': [2810], 'sorting,': [2814], 'Mann-Whitney': [2816], 'U': [2817], 'applied.': [2820], 'Results': [2821], 'obtained': [2823], 'sister': [2826, 3427, 3544], 'independent': [2829], 'expressed': [2832], 'means': [2834], '±': [2835, 2954, 2958, 2979, 2983, 3053, 3247, 3249, 3254, 3256, 3261, 3263, 3267, 3269, 3274, 3276, 3278, 3280, 3284, 3286, 3290, 3292, 3294, 3296, 3300, 3302, 3305, 3307, 3310, 3312, 3315, 3317, 4151, 4178, 4182], 'S.E.': [2836], '(n': [2837, 2961, 3424, 3541], '=': [2838, 2962, 3057, 3425, 3542, 4156], '3–6': [2839], 'cultures).': [2840, 3428, 3545], 'identify': [2842], 'whether': [2843], 'functional': [2848, 2930, 3077], 'not,': [2856], 'ng/ml).': [2878], '30-min': [2881, 3040], 'incubation': [2882, 3041, 3051, 3321, 3438, 4136], 'concentrations': [2886], 'radioactive': [2898], 'ligand': [2899, 2992, 3339, 3456], 'measured.': [2903], 'values': [2905, 3365, 3482], 'bound': [2907], 'Scatchard': [2913], 'plot': [2914], 'analysis,': [2915], 'number': [2919, 3157], '(B': [2920, 2999], 'max)': [2921, 3000], 'dissociation': [2924, 2968], 'constant': [2925, 2969], '(K': [2926, 2974], 'd)': [2927, 2975], 'determined': [2934, 3015, 4132], '(Fig.1': [2939], 'A).': [2940, 3152, 3905, 4140], 'TheB': [2941], 'max': [2942], '3.88': [2953], '0.05': [2955], '4.96': [2957], '0.27': [2959], 'pmol/mg': [2960], '4,': [2963, 3058], 'p': [2964, 3059, 3414, 3421, 3531, 3538, 4158], '<': [2965, 3060, 3415, 3418, 3422, 3532, 3535, 3539, 4159], '0.05).': [2966], '192': [2978], '286': [2982], '26': [2984], 'nm.': [2985], 'course': [2988], 'maximum': [2991], 'assessed': [3002, 3548, 4301], 'stimulating': [3004], 'periods': [3010], 'exposing': [3017], 'them': [3018], 'submaximal': [3021, 3335, 3452], 'concentration': [3022, 3336, 3453], '(250': [3025, 3340, 3457], 'nm;': [3026], 'Fig.': [3027], 'B).': [3029, 3578, 3921, 4221], 'further': [3045, 3190], 'until': [3047], '(277': [3052], '10%': [3054], 'control,n': [3056], '0.0001).': [3061], 'redistribution': [3070, 3092], 'receptors,': [3073, 3095, 4045], 'leading': [3074, 3723], 'increase': [3080, 3219, 3596, 3765, 3960, 4124, 4276, 4312, 4323], 'surface.': [3084], 'determine': [3086], 'several': [3096], 'processes': [3102], '(brefeldin': [3105], 'NEM)': [3111], 'endocytosis': [3113], '(bafilomycin': [3114], 'A)': [3115], 'prior': [3124], '(Table': [3149, 3575, 3755], 'I,': [3150, 3576, 3756], 'part': [3151, 3577, 3757], 'stimulation,': [3155], 'estimated': [3166, 3348, 3465], 'ligand-binding': [3168, 4215], '[3H]AMPA.': [3171], 'Bafilomycin': [3172], 'which': [3174], 'blocks': [3175], 'trans-Golgi': [3176], 'transport': [3177], 'inhibit': [3179], 'basal': [3182, 3777, 3810, 3840], 'elevated': [3191], 'levels.': [3193, 3844], 'contrast,': [3195, 3601, 4162], 'blockers,': [3198, 3235, 4000], 'reduced': [3208, 3775], 'effects.': [3211], 'drug': [3213], 'sensitivity': [3214], 'suggests': [3215, 3796], 'BDNF-triggered': [3218, 3595], 'reflects': [3223], 'receptors.Table': [3229], 'IEffects': [3230], 'chelators,': [3233], 'BDNF-mediated': [3240], 'receptorsReagentControl+BDNFA.Control100': [3246], '15171': [3248], '12**1': [3250], 'A166': [3253], '16**206': [3255], '10*5': [3257], 'A111': [3260], '15136': [3262], '111': [3264], 'NEM102': [3266], '24133': [3268], '17100': [3270], 'toxin89': [3273], '6101': [3275], '11B.Control100': [3277], '3150': [3279], '6***5': [3281], 'BAPTA84': [3283], '5*132': [3285], '5**0.1': [3287], 'BAPTA-AM85': [3289], '1795': [3291], '4C.Control100': [3293], '2153': [3295], '2***1': [3297], 'μmcalphostin': [3298], 'C87': [3299], '2*96': [3301], '610': [3303], 'μmU7312248': [3304], '1**135': [3306], '8***25': [3308], 'μmPD9805999': [3309], '2120': [3311], '2*0.5': [3313], 'μmKN9353': [3314], '1**84': [3316], '5***After': [3318], '3-h': [3320, 3437], 'cortical': [3331, 3448, 4280, 4315], 'nm).': [3341, 3458], 'Nonspecific': [3342, 3459], 'background': [3343, 3460], 'subtracted': [3362, 3479], 'raw': [3364, 3481], 'binding.': [3368, 3485, 3599, 3768], 'normalized': [3372, 3489], 'yields,': [3375, 3492], 'although': [3376, 3493], 'they': [3377, 3494], 'significantly': [3380, 3497, 4017, 4175], 'influenced': [3381, 3498, 3817, 4176], 'any': [3383, 3500], 'treatment.': [3384, 3501], 'Comparison': [3385, 3502], 'done': [3387, 3504], 'BDNF-treated': [3389, 3506], 'untreated': [3391, 3409, 3508, 3526], 'pairs': [3392, 3509], 'each': [3394, 3511, 4090, 4107], '(right': [3395, 3512], 'column).': [3396, 3412, 3513, 3529], 'Basal': [3397, 3514], 'statistically': [3405, 3522], 'comparison': [3407, 3524], 'control': [3410, 3527], '(middle': [3411, 3528], '*,': [3413, 3530], '0.05;': [3416, 3533], '**,p': [3417, 3534], '0.01;': [3419, 3536], '***,': [3420, 3537], '0.001': [3423, 3540], 'Open': [3429], 'table': [3430], 'new': [3433], 'tab': [3434], 'Second,': [3546], 'involvement': [3550, 4061], 'chelator,': [3555], 'derivative.': [3559], 'Intracellular': [3560], 'trapped': [3563], 'cell-permeable': [3565], 'BAPTA-AM,': [3566, 3821], 'chelated': [3571], 'nonpermeable': [3573], 'BAPTA': [3574, 3602, 3819], 'Under': [3579], 'condition,': [3581], '3': [3590, 4220], 'BAPTA-AM': [3592], 'had': [3603], 'no': [3604], 'significant': [3605], 'effect.': [3606], 'findings': [3609], 'suggest': [3610, 4014], 'involves': [3620], 'pathway': [3623, 3836], '(37Kuijpers': [3628], 'T.W.': [3629], 'Hoogerwerf': [3630], 'Roos': [3632], 'Immunol.': [3635], '1992;': [3636], '148:': [3637], '72-77Google': [3638], 'trigger': [3644, 3926], 'signaling': [3646, 3835], 'cascades': [3647], 'phospholipase': [3649], 'mitogen-activated': [3652], 'kinase.': [3654], '(PKC)': [3660], 'αCAMKII': [3662], 'often': [3664], "(26O'Brien": [3673], 'signals': [3722], 'increase,': [3729], 'stimulated': [3733, 4226], 'inhibitors,': [3741, 3829], 'U73122': [3742, 3770], '(phospholipase': [3743], 'C),': [3744], '(mitogen-activated': [3746], 'kinase),': [3748], '(PKC),': [3751], '(αCAMKII)': [3754], 'C).': [3758, 3994], 'Calphostin': [3759], 'almost': [3761], 'abolished': [3762], 'Although': [3769], 'themselves': [3773], 'markedly': [3774, 3783, 3895, 4237], 'binding,': [3779], 'still': [3782], 'up-regulated': [3784], 'inhibitors.': [3793], 'observation': [3795], 'PKC': [3798], 'may': [3800, 4188], 'involve': [3801, 4259], 'receptors.': [3807], 'As': [3808], 'modestly': [3816], 'alternative': [3834], 'confirm': [3846], 'distributions': [3852], 'proteins,': [3858], 'surfaces': [3874], 'biotinylated,': [3876], 'collected': [3877], 'streptavidin-coupled': [3879], 'beads,': [3880], 'blotting.': [3885], 'biotinylated': [3887], '(cell': [3888], 'surface-expressed)': [3889], 'GluR2/3': [3892, 4327], 'compared': [3900], 'nontreated': [3902], '(Fig.2': [3904], 'parallel,': [3907], '(Fig.': [3919, 3992, 4219], '(32Takei': [3932], 'Is': [3950], 'receptors?': [3963], 'examine': [3965], 'effect,': [3974], 'NMDA-type': [3976], 'AMPA-type': [3978], 'blocked': [3982], 'AP-5': [3986], 'CNQX': [3988], 'culture,': [3990], 'respectively': [3991], 'similarly': [4002], 'altered': [4018], 'surface,': [4027], 'irrespective': [4028], 'activities.': [4032], 'attempted': [4047], 'reconstitute': [4049], 'non-neuronal': [4054], 'excluded': [4059], 'elements': [4064], 'processes.': [4067], 'permanent': [4076], 'integration': [4077], 'gene': [4081], 'under': [4082], 'cytomegalovirus': [4084], 'promoter.': [4085], 'By': [4086], 'transfecting': [4087], 'subunit,': [4109], 'evaluated': [4114], '5-h': [4135], '(Fig.3': [4139], 'up-regulation': [4142], 'pronounced': [4147], '(392': [4150], 'control,': [4154, 4185], '3,': [4157], '0.01).': [4160], 'cadherins': [4172], '(103': [4177], '15%': [4179], '106': [4181], '7%': [4183], 'respectively).': [4186], 'eliminate': [4189], 'possibility': [4191], 'simply': [4194], 'facilitates': [4195], 'general': [4196], 'turnover': [4197], 'membranes.': [4200], 'distribution': [4204], 'active': [4207], 'ascertained': [4212], 'When': [4222], 'indicate': [4250], 'specifically': [4258], 'rates': [4274], '(38Takei': [4282], 'Hara': [4286], 'Yonezawa': [4288], '42818-42825Google': [4297], 'Thus,': [4299], 'lagged': [4329], 'behind': [4330]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2129114790', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-09T07:06:06.047516', 'created_date': '2016-06-24'}