Title: Formation of Monounsaturated Fatty Acids in Fatty Liver
Abstract: 1. Monoenoic acid formation from stearic acid was studied with liver preparations from starved and CCl4-intoxicated rats. The rate of monounsaturation decreased both in starved and CCl4-treated animals, while the oleic acid content increased in preparations of these fatty livers. Freeze-thawing of liver preparations reduced the desaturating activity. 2. The 14C-distribution pattern in oleic acid molecules derived from 1-14-stearic acid and from 1-14G-acetic acid, suggests that an intact 18-carbon unit is converted directly to oleic acid even in fatty liver, and that acetic acid may serve as a precursor of oleic acid only via stearic acid.
Publication Year: 1967
Publication Date: 1967-06-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 5
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