Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2128698072', 'doi': 'https://doi.org/10.1371/journal.pone.0043343', 'title': 'RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma', 'display_name': 'RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma', 'publication_year': 2012, 'publication_date': '2012-08-14', 'ids': {'openalex': 'https://openalex.org/W2128698072', 'doi': 'https://doi.org/10.1371/journal.pone.0043343', 'mag': '2128698072', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22905260', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3419170'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043343', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043343&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043343&type=printable', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084027043', 'display_name': 'Shiri Weinstein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I16391192', 'display_name': 'Tel Aviv University', 'ror': 'https://ror.org/04mhzgx49', 'country_code': 'IL', 'type': 'education', 'lineage': ['https://openalex.org/I16391192']}], 'countries': ['IL'], 'is_corresponding': True, 'raw_author_name': 'Shiri Weinstein', 'raw_affiliation_strings': ['Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}, {'raw_affiliation_string': 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085041493', 'display_name': 'Rafi Emmanuel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I16391192', 'display_name': 'Tel Aviv University', 'ror': 'https://ror.org/04mhzgx49', 'country_code': 'IL', 'type': 'education', 'lineage': ['https://openalex.org/I16391192']}], 'countries': ['IL'], 'is_corresponding': True, 'raw_author_name': 'Rafi Emmanuel', 'raw_affiliation_strings': ['Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}, {'raw_affiliation_string': 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031334804', 'display_name': 'Ashley M. Jacobi', 'orcid': 'https://orcid.org/0000-0002-9364-6518'}, 'institutions': [{'id': 'https://openalex.org/I69230048', 'display_name': 'Integrated DNA Technologies (United States)', 'ror': 'https://ror.org/009jvpf03', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I69230048']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Ashley M. Jacobi', 'raw_affiliation_strings': ['Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America'], 'affiliations': [{'raw_affiliation_string': 'Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America', 'institution_ids': ['https://openalex.org/I69230048']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011217358', 'display_name': 'Abraham Avigdor', 'orcid': 'https://orcid.org/0000-0002-7448-869X'}, 'institutions': [{'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': True, 'raw_author_name': 'Avigdor Abraham', 'raw_affiliation_strings': ['Division of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel', 'institution_ids': ['https://openalex.org/I2799810450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025891234', 'display_name': 'Mark A. Behlke', 'orcid': 'https://orcid.org/0000-0002-4218-857X'}, 'institutions': [{'id': 'https://openalex.org/I69230048', 'display_name': 'Integrated DNA Technologies (United States)', 'ror': 'https://ror.org/009jvpf03', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I69230048']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Mark A. Behlke', 'raw_affiliation_strings': ['Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America'], 'affiliations': [{'raw_affiliation_string': 'Integrated DNA Technologies, Inc., Coralville, Iowa, United States of America', 'institution_ids': ['https://openalex.org/I69230048']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051648002', 'display_name': 'Andrew Sprague', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145311141', 'display_name': 'Alnylam Pharmaceuticals (United States)', 'ror': 'https://ror.org/00thr3w71', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I145311141']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Andrew G. Sprague', 'raw_affiliation_strings': ['Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America'], 'affiliations': [{'raw_affiliation_string': 'Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America', 'institution_ids': ['https://openalex.org/I145311141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019685125', 'display_name': 'Tatiana I. Novobrantseva', 'orcid': 'https://orcid.org/0000-0001-8070-403X'}, 'institutions': [{'id': 'https://openalex.org/I145311141', 'display_name': 'Alnylam Pharmaceuticals (United States)', 'ror': 'https://ror.org/00thr3w71', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I145311141']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Tatiana I. Novobrantseva', 'raw_affiliation_strings': ['Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America'], 'affiliations': [{'raw_affiliation_string': 'Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America', 'institution_ids': ['https://openalex.org/I145311141']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058925624', 'display_name': 'Arnon Nagler', 'orcid': 'https://orcid.org/0000-0002-0763-1265'}, 'institutions': [{'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': True, 'raw_author_name': 'Arnon Nagler', 'raw_affiliation_strings': ['Division of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel', 'institution_ids': ['https://openalex.org/I2799810450']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5038855686', 'display_name': 'Dan Peer', 'orcid': 'https://orcid.org/0000-0001-8238-0673'}, 'institutions': [{'id': 'https://openalex.org/I16391192', 'display_name': 'Tel Aviv University', 'ror': 'https://ror.org/04mhzgx49', 'country_code': 'IL', 'type': 'education', 'lineage': ['https://openalex.org/I16391192']}], 'countries': ['IL'], 'is_corresponding': True, 'raw_author_name': 'Dan Peer', 'raw_affiliation_strings': ['Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}, {'raw_affiliation_string': 'Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5084027043', 'https://openalex.org/A5085041493', 'https://openalex.org/A5031334804', 'https://openalex.org/A5011217358', 'https://openalex.org/A5025891234', 'https://openalex.org/A5051648002', 'https://openalex.org/A5019685125', 'https://openalex.org/A5058925624', 'https://openalex.org/A5038855686'], 'corresponding_institution_ids': ['https://openalex.org/I16391192', 'https://openalex.org/I16391192', 'https://openalex.org/I69230048', 'https://openalex.org/I2799810450', 'https://openalex.org/I69230048', 'https://openalex.org/I145311141', 'https://openalex.org/I145311141', 'https://openalex.org/I2799810450', 'https://openalex.org/I16391192'], 'apc_list': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'apc_paid': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'fwci': 1.735, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 26, 'citation_normalized_percentile': {'value': 0.800058, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '7', 'issue': '8', 'first_page': 'e43343', 'last_page': 'e43343'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10583', 'display_name': 'The p53 Signaling Network in Cancer Research', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10185', 'display_name': 'Lymphoid Neoplasms', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10685', 'display_name': 'Viral-Related Cancers in Immunocompromised Patients', 'score': 0.9961, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cyclin-b', 'display_name': 'Cyclin B', 'score': 0.588097}, {'id': 'https://openalex.org/keywords/mantle-cell-lymphoma', 'display_name': 'Mantle Cell Lymphoma', 'score': 0.574135}, {'id': 'https://openalex.org/keywords/cell-cycle', 'display_name': 'Cell Cycle', 'score': 0.537848}, {'id': 'https://openalex.org/keywords/cyclin-d', 'display_name': 'Cyclin D', 'score': 0.52087593}, {'id': 'https://openalex.org/keywords/cancer-therapy', 'display_name': 'Cancer Therapy', 'score': 0.514965}, {'id': 'https://openalex.org/keywords/cyclin-a2', 'display_name': 'Cyclin A2', 'score': 0.50936234}, {'id': 'https://openalex.org/keywords/cyclin-d2', 'display_name': 'Cyclin D2', 'score': 0.42259213}], 'concepts': [{'id': 'https://openalex.org/C2777525834', 'wikidata': 'https://www.wikidata.org/wiki/Q268713', 'display_name': 'Mantle cell lymphoma', 'level': 3, 'score': 0.92421937}, {'id': 'https://openalex.org/C199835354', 'wikidata': 'https://www.wikidata.org/wiki/Q15311861', 'display_name': 'Cyclin D1', 'level': 4, 'score': 0.9149865}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.6660767}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6402438}, {'id': 'https://openalex.org/C9743823', 'wikidata': 'https://www.wikidata.org/wiki/Q5198264', 'display_name': 'Cyclin B', 'level': 5, 'score': 0.588097}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.54884326}, {'id': 'https://openalex.org/C119056186', 'wikidata': 'https://www.wikidata.org/wiki/Q1431332', 'display_name': 'Gene silencing', 'level': 3, 'score': 0.54746526}, {'id': 'https://openalex.org/C11882975', 'wikidata': 'https://www.wikidata.org/wiki/Q24781041', 'display_name': 'Cyclin D', 'level': 5, 'score': 0.52087593}, {'id': 'https://openalex.org/C28179978', 'wikidata': 'https://www.wikidata.org/wiki/Q5198263', 'display_name': 'Cyclin A2', 'level': 5, 'score': 0.50936234}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.46486837}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.46250245}, {'id': 'https://openalex.org/C166703698', 'wikidata': 'https://www.wikidata.org/wiki/Q201993', 'display_name': 'RNA interference', 'level': 4, 'score': 0.4536367}, {'id': 'https://openalex.org/C2780733254', 'wikidata': 'https://www.wikidata.org/wiki/Q5198271', 'display_name': 'Cyclin D2', 'level': 5, 'score': 0.42259213}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.37527955}, {'id': 'https://openalex.org/C2779338263', 'wikidata': 'https://www.wikidata.org/wiki/Q208414', 'display_name': 'Lymphoma', 'level': 2, 'score': 0.30919236}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.27011532}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.24840617}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.19521144}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.14999673}], 'mesh': [{'descriptor_ui': 'D019938', 'descriptor_name': 'Cyclin D1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020522', 'descriptor_name': 'Lymphoma, Mantle-Cell', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D034622', 'descriptor_name': 'RNA Interference', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002453', 'descriptor_name': 'Cell Cycle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019938', 'descriptor_name': 'Cyclin D1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053487', 'descriptor_name': 'DEAD-box RNA Helicases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053487', 'descriptor_name': 'DEAD-box RNA Helicases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020868', 'descriptor_name': 'Gene Silencing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020522', 'descriptor_name': 'Lymphoma, Mantle-Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D043244', 'descriptor_name': 'Ribonuclease III', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D043244', 'descriptor_name': 'Ribonuclease III', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043343', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043343&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/e9ae1dcc0b94471fb49278df650ba05d', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3419170', 'pdf_url': 'https://europepmc.org/articles/pmc3419170?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419170', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22905260', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0043343', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0043343&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.73, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1965008416', 'https://openalex.org/W1992708996', 'https://openalex.org/W1994066190', 'https://openalex.org/W2006741426', 'https://openalex.org/W2011531618', 'https://openalex.org/W2020086002', 'https://openalex.org/W2020619763', 'https://openalex.org/W2029080338', 'https://openalex.org/W2079237350', 'https://openalex.org/W2085913508', 'https://openalex.org/W2089921110', 'https://openalex.org/W2106392930', 'https://openalex.org/W2119212619', 'https://openalex.org/W2134002582', 'https://openalex.org/W2144333395', 'https://openalex.org/W2156451974', 'https://openalex.org/W2557036084'], 'related_works': ['https://openalex.org/W3103464621', 'https://openalex.org/W2484424499', 'https://openalex.org/W2157729483', 'https://openalex.org/W2086107112', 'https://openalex.org/W2067936126', 'https://openalex.org/W2064039108', 'https://openalex.org/W2039496237', 'https://openalex.org/W2026382359', 'https://openalex.org/W1980138415', 'https://openalex.org/W1507530325'], 'abstract_inverted_index': {'Mantle': [0], 'cell': [1, 29, 67, 78, 97], 'lymphoma': [2, 98], 'is': [3, 33], 'characterized': [4], 'by': [5], 'a': [6, 25, 62, 93], 'genetic': [7], 'translocation': [8], 'results': [9, 88], 'in': [10, 40, 74, 105], 'aberrant': [11], 'overexpression': [12], 'of': [13, 27, 43, 85], 'the': [14, 28, 41, 44, 101], 'CCND1': [15], 'gene,': [16], 'which': [17], 'encodes': [18], 'cyclin': [19, 57, 71, 90], 'D1.': [20], 'This': [21], 'protein': [22], 'functions': [23], 'as': [24, 61, 92], 'regulator': [26], 'cycle': [30, 79], 'progression,': [31], 'hence': [32], 'considered': [34], 'to': [35, 54], 'play': [36], 'an': [37], 'important': [38], 'role': [39], 'pathogenesis': [42], 'disease.': [45], 'In': [46], 'this': [47], 'study,': [48], 'we': [49], 'used': [50], 'RNA': [51], 'interference': [52], 'strategies': [53], 'examine': [55], 'whether': [56], 'D1': [58, 72, 91], 'might': [59], 'serve': [60], 'therapeutic': [63, 102], 'target': [64, 94], 'for': [65, 95], 'mantle': [66, 96], 'lymphoma.': [68], 'Knocking': [69], 'down': [70], 'resulted': [73], 'significant': [75], 'growth': [76], 'retardation,': [77], 'arrest,': [80], 'and': [81, 99], 'most': [82], 'importantly,': [83], 'induction': [84], 'apoptosis.': [86], 'These': [87], 'mark': [89], 'emphasize': [100], 'potential': [103], 'hidden': [104], 'its': [106], 'silencing.': [107]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2128698072', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 5}], 'updated_date': '2024-08-21T16:53:40.907512', 'created_date': '2016-06-24'}