Publication Information

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[26], 'during': [27, 205], 'replication,': [28], 'it': [29], 'moves': [30], 'along': [31], 'DNA': [33, 109, 148], 'with': [34, 90], 'MCM': [35, 196, 213], 'helicase.': [36], 'When': [37], 'progression': [39], 'inhibited,': [41], 'checkpoint': [42, 111, 123], 'regulation': [43], 'believed': [45], 'stabilize': [47], 'fork;': [50], 'detailed': [52], 'mechanism,': [53], 'however,': [54], 'remains': [55], 'unclear.': [56], 'To': [57], 'examine': [58], 'relationship': [60], 'between': [61], 'initiation': [63], 'and': [64, 67, 81, 83, 97, 113, 140, 212], 'elongation': [65, 72], 'defects': [66], 'response': [69], 'block,': [73], 'we': [74], 'used': [75], 'fission': [76], 'yeast': [77], 'mutants': [78], 'Orc1': [80], 'Cdc45--orp1-4': [82], 'sna41-928,': [84], 'respectively--at': [85], 'their': [86], 'respective': [87], 'semipermissive': [88], 'temperatures': [89], 'regard': [91], 'BrdU': [93], 'incorporation.': [94], 'Both': [95], 'orp1': [96, 156], 'sna41': [98, 159, 168, 176], 'cells': [99], 'exhibited': [100], 'HU': [101, 163, 183, 199], 'hypersensitivity': [102], 'in': [103, 116, 180], 'absence': [105], 'Chk1,': [107], 'a': [108, 121], 'damage': [110], 'kinase,': [112, 124], 'were': [114], 'defective': [115], 'full': [117], 'activation': [118], 'Cds1,': [120], 'indicating': [125], 'that': [126, 171], 'normal': [127], 'required': [130, 136], 'for': [131], 'Cds1': [132, 139, 187], 'activation.': [133], 'Mrc1': [134, 207], 'activate': [138], 'prevent': [141], 'machinery': [144], 'from': [145, 147, 182], 'uncoupling': [146], 'synthesis.': [149], 'We': [150], 'observed': [151], 'that,': [152], 'while': [153], 'either': [154], 'or': [157], 'mutation': [160], 'partially': [161], 'suppressed': [162, 170, 197], 'sensitivity': [164, 200], 'cds1': [166], 'cells,': [167], 'specifically': [169], 'mrc1': [173, 202], 'cells.': [174, 203], 'Interestingly,': [175], 'alleviated': [177], 'defect': [179], 'recovery': [181], 'arrest': [184], 'without': [185], 'increasing': [186], 'activity.': [188], 'addition': [190], 'sna41,': [192], 'specific': [193], 'mutations': [194], 'Thus,': [204], 'elongation,': [206], 'may': [208], 'negatively': [209], 'regulate': [210], 'helicase': [214], 'render': [216], 'stalled': [217], 'forks': [218], 'capable': [219], 'resuming': [221], 'replication.': [222]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2128662391', 'counts_by_year': [{'year': 2021, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 4}], 'updated_date': '2024-12-11T21:07:14.019941', 'created_date': '2016-06-24'}