Publication Information

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2786, 2909, 2949, 2965, 3162, 3197, 3578, 3881, 4222], 'Management': [13, 1710, 2905, 2934, 3626], 'Primary': [15], 'Vesicoureteral': [16, 202], 'Reflux': [17, 203, 511], 'in': [18, 207, 218, 406, 442, 496, 508, 613, 672, 882, 902, 995, 1083, 1109, 1238, 1398, 1428, 1515, 1526, 1558, 1610, 1653, 1778, 1798, 1828, 1859, 1899, 1939, 1987, 2028, 2079, 2094, 2117, 2159, 2210, 2280, 2310, 2337, 2468, 2504, 2542, 2616, 2750, 2753, 2792, 2842, 2932, 2940, 2961, 2969, 3011, 3035, 3053, 3089, 3107, 3145, 3212, 3226, 3344, 3411, 3444, 3527, 3533, 3827, 3939, 3941, 4063, 4132, 4150, 4203], 'Children': [19, 3686], 'Craig': [20, 55], 'A.': [21, 56, 58], 'Peters,': [22], 'Steven': [23, 66], 'J.': [24, 42, 67, 69, 133, 135], 'Skoog,': [25], 'Billy': [26, 77], 'S.': [27, 33, 78, 80, 100, 102], 'Arant,': [28], 'Hillary': [29, 88], 'L.': [30, 89, 91], 'Copp,': [31], 'Jack': [32, 99], 'Elder,': [34], 'R.': [35, 110], 'Guy': [36, 111, 113], 'Hudson,': [37], 'Antoine': [38, 121], 'E.': [39, 122, 124], 'Khoury,': [40], 'Armando': [41, 132], 'Lorenzo,': [43], 'Hans': [44, 143], 'G.': [45, 144, 146], 'Pohl,': [46], 'Ellen': [47, 154], 'Shapiro,': [48], 'Warren': [49, 163], 'T.': [50, 164, 166], 'Snodgrass,': [51], 'and': [52, 174, 246, 278, 281, 291, 313, 340, 359, 378, 416, 429, 460, 464, 513, 522, 546, 555, 573, 599, 639, 644, 685, 705, 723, 737, 744, 781, 793, 795, 802, 808, 813, 853, 953, 967, 981, 990, 1036, 1071, 1076, 1098, 1106, 1132, 1151, 1162, 1214, 1228, 1255, 1283, 1307, 1316, 1322, 1351, 1359, 1362, 1369, 1374, 1389, 1402, 1431, 1438, 1450, 1459, 1533, 1548, 1551, 1567, 1571, 1580, 1605, 1658, 1696, 1735, 1742, 1806, 1842, 1885, 1896, 1927, 1943, 1974, 2010, 2012, 2034, 2082, 2162, 2209, 2239, 2250, 2277, 2307, 2344, 2363, 2389, 2454, 2494, 2571, 2590, 2635, 2656, 2744, 2747, 2760, 2811, 2835, 2891, 2926, 3129, 3147, 3189, 3230, 3295, 3325, 3338, 3353, 3379, 3409, 3472, 3493, 3557, 3569, 3619, 3639, 3722, 3730, 3748, 3757, 3766, 3776, 3845, 3913, 3960, 3992, 4080, 4112, 4122, 4164, 4179, 4209], 'Mireya': [53, 175], 'Diaz': [54, 177], 'PetersCraig': [57], 'Peters': [59], 'More': [60, 71, 82, 93, 104, 115, 126, 137, 148, 157, 168, 178], 'articles': [61, 72, 83, 94, 105, 116, 127, 138, 149, 158, 169, 179, 328, 358, 426], 'by': [62, 73, 84, 95, 106, 117, 128, 139, 150, 159, 170, 180, 399, 1380, 1771, 1928, 2387, 2625, 2668, 3235, 4173, 4220], 'this': [63, 74, 85, 96, 107, 118, 129, 140, 151, 160, 171, 181, 295, 443, 903, 1233, 1626, 1999, 2016, 2321, 2543, 2594, 2808, 2821, 3504, 3552, 3607, 3828], 'author': [64, 75, 86, 97, 108, 119, 130, 141, 152, 161, 172, 182], ',': [65, 76, 87, 98, 109, 120, 131, 142, 153, 162, 173], 'SkoogSteven': [68], 'Skoog': [70], 'ArantBilly': [79], 'Arant': [81], 'CoppHillary': [90], 'Copp': [92], 'ElderJack': [101], 'Elder': [103], 'HudsonR.': [112], 'Hudson': [114], 'KhouryAntoine': [123], 'Khoury': [125], 'LorenzoArmando': [134], 'Lorenzo': [136], 'PohlHans': [145], 'Pohl': [147], 'ShapiroEllen': [155], 'Shapiro': [156], 'SnodgrassWarren': [165], 'Snodgrass': [167], 'DiazMireya': [176], 'View': [183], 'All': [184], 'Author': [185], 'Informationhttps://doi.org/10.1016/j.juro.2010.05.065AboutAbstractPDF': [186], 'ToolsAdd': [187], 'to': [188, 210, 230, 238, 261, 302, 323, 365, 505, 561, 604, 633, 700, 707, 711, 759, 764, 868, 877, 928, 1068, 1174, 1231, 1241, 1289, 1327, 1342, 1366, 1411, 1442, 1479, 1487, 1493, 1513, 1545, 1563, 1574, 1629, 1647, 1725, 1922, 1984, 1997, 2005, 2112, 2151, 2172, 2200, 2358, 2443, 2459, 2464, 2496, 2554, 2573, 2582, 2586, 2740, 2803, 2816, 2823, 2897, 2901, 3136, 3140, 3156, 3264, 3302, 3307, 3328, 3382, 3485, 3544, 3662, 3674, 3704, 3726, 3787, 3853, 3859, 3909, 3930, 3965, 3999, 4015, 4036, 4072, 4102], 'favoritesDownload': [189], 'CitationsTrack': [190], 'CitationsPermissionsReprints': [191], 'ShareFacebookTwitterLinked': [192], 'InEmail': [193], 'Abstract': [194], 'Purpose:': [195], 'The': [196, 221, 315, 336, 362, 391, 411, 475, 525, 615, 833, 1060, 1202, 1387, 1435, 1716, 1744, 1948, 1966, 1977, 2365, 2400, 2577, 2638, 2827, 2935, 2956, 2980, 3002, 3028, 3363, 3483, 3572, 3668, 3710, 3778, 4105, 4120, 4139, 4198], 'American': [197, 659, 3897], 'Urological': [198, 660], 'Association': [199, 661], 'established': [200, 484], 'Update': [205], 'Committee': [206], 'July': [208], '2005': [209], 'update': [211, 701], 'management': [213, 234, 240, 534, 667, 770, 782, 788, 1212, 1430, 2736, 2839, 2943, 3056, 3124, 3420, 4205], 'primary': [215, 669, 3890], 'vesicoureteral': [216, 232, 376, 458, 532, 611, 670, 692], 'reflux': [217, 233, 265, 377, 459, 533, 612, 671, 1064, 1609, 1853, 2281, 2501, 2983, 3074, 3087, 3214, 3568, 4128], 'children': [219, 262, 374, 562, 720, 772, 790, 1088, 1399, 1750, 1799, 1860, 1918, 2095, 2181, 2264, 2393, 2417, 2617, 2660, 2962, 2992, 3012, 3036, 3054, 3078, 3090, 3108, 3286, 3510, 3880, 3987, 4151, 4223], 'guideline.': [220], 'Panel': [222, 316, 526, 699, 863, 1624, 2639, 3364, 4140, 4213], 'defined': [223, 380, 4208], 'task': [225], 'into': [226, 344, 418], '5': [227, 332, 766], 'topics': [228, 767, 835], 'pertaining': [229, 260], 'specific': [231, 346, 388, 560, 1418, 2317, 3267, 4181], 'issues,': [235], 'which': [236, 915, 937, 2320], 'correspond': [237], '3': [242, 827, 898, 2072], 'distinct': [243, 251], 'index': [244, 252, 1826], 'patients': [245, 439, 805, 1045, 1293, 1841, 2029, 2080, 2282, 2471, 2481, 3534, 3940, 4064, 4070], 'screening': [248, 690, 716, 799, 810, 834, 2552, 2559, 2580, 2627, 2727, 4125], '2': [250, 2201], 'patients.': [253, 1901], 'This': [254, 445, 818, 1040, 2085, 2530, 3963, 4019], 'report': [255], 'summarizes': [256, 820], 'existing': [258, 1270], 'evidence': [259, 275, 288, 296, 736, 852, 948, 974, 3241, 3943, 4097], 'with': [263, 287, 330, 375, 485, 594, 683, 721, 726, 777, 785, 791, 806, 815, 875, 960, 987, 1005, 1014, 1046, 1118, 1294, 1301, 1309, 1371, 1638, 1688, 1714, 1722, 1751, 1781, 1803, 1830, 1834, 1861, 1919, 2030, 2081, 2096, 2204, 2265, 2299, 2405, 2423, 2448, 2521, 2523, 2548, 2661, 2692, 2719, 2768, 2780, 2963, 2971, 2993, 3013, 3037, 3093, 3179, 3323, 3351, 3377, 3404, 3423, 3442, 3468, 3511, 3585, 3630, 3687, 3724, 3818, 3887, 3896, 3933, 3952, 3988, 4065, 4152, 4224], 'diagnosed': [264, 728], 'including': [266, 1127, 1640, 2913, 3125, 3491, 3554, 3616, 3719, 3742, 3762], 'those': [267, 282, 1300, 1308, 1829, 1923, 2035, 2621, 2853, 2970, 3545, 3951], 'young': [268], 'or': [269, 1204, 1383, 1474, 1482, 1591, 2100, 2126, 2286, 2557, 2624, 2664, 3097, 3111, 3314, 3452, 3652, 3680, 3702, 3864, 3893, 3921], 'older': [270, 283, 773, 2452, 2480, 2845, 3347, 3373, 3464, 3961], 'than': [271, 284, 774, 957, 1782, 1831, 2395, 2419, 2437, 2450, 2479, 2516, 2620, 2649, 2687, 2714, 2846, 2858, 2973, 2995, 3014, 3039, 3288, 3348, 3374, 3465], '1': [272, 285, 775, 958, 2187, 2199, 2235, 2369, 2396, 2420, 2438, 2650, 2831, 2847, 2859, 3349, 3375, 3466, 3706], 'year': [273, 286, 776, 2397, 2421, 2439, 2518, 2651, 2689, 2716, 2848, 3350, 3376, 3401, 3439, 3467, 4060], 'without': [274, 1783, 1832, 1924, 2083, 2301, 2974, 2996, 3015, 3040, 3359, 3389, 3421, 4050], 'bladder': [277, 290, 463, 521, 572, 794, 1358, 1396, 1426, 1437, 1766, 3177], 'bowel': [279, 292, 465, 523, 574, 796, 1360, 1439], 'dysfunction': [280, 466, 1397, 1427, 1440], 'dysfunction.': [293, 524, 575], 'From': [294, 850], 'clinical': [297, 305, 389, 499, 531, 742, 933, 984, 1559, 2313, 2867, 2911, 3240, 4106, 4182], 'practice': [298, 638], 'guidelines': [299, 529, 558, 608, 628, 652, 713, 976, 1991, 3660], 'were': [300, 350, 414, 427, 431, 440, 747, 859, 2248, 2384], 'developed': [301], 'manage': [303], 'scenarios': [306], 'insofar': [307], 'as': [308, 467, 494, 566, 568, 687, 689, 1050, 1052, 1135, 1137, 1446, 1448, 1502, 1646, 1769, 2135, 3223, 3386, 3513, 3733, 3786, 3800, 3802, 3820, 3822, 4029], 'data': [310, 413, 430, 596, 649, 738, 756, 858, 1871, 2130, 2147, 2258, 2292, 2401, 2603, 2802, 3154, 3196, 3263, 3703, 4014, 4043], 'permit.': [311], 'Materials': [312], 'Methods:': [314], 'searched': [317], 'MEDLINE®': [319], 'database': [320, 337], 'from': [321, 433, 437, 740, 830, 2360, 2538, 2852, 2888, 2952], '1994': [322], '2008': [324], 'for': [325, 471, 530, 577, 609, 637, 642, 691, 714, 914, 930, 1057, 1149, 1183, 1218, 1281, 1349, 1457, 1491, 1670, 1746, 1840, 1844, 1894, 1953, 2143, 2319, 2382, 2416, 2512, 2645, 2659, 2683, 2764, 2838, 2854, 2937, 2991, 3022, 3171, 3256, 3270, 3281, 3285, 3320, 3370, 3396, 3429, 3434, 3489, 3508, 3614, 3728, 3731, 3755, 3793, 3810, 3834, 3878, 4115, 4127, 4188], 'all': [326, 1252, 2160, 2263, 2424, 3663], 'relevant': [327, 607, 741], 'dealing': [329, 682], 'chosen': [333], 'guideline': [334, 664, 822, 865], 'topics.': [335], 'was': [338, 409, 1981, 2003, 2017, 2190, 2197, 2206, 2217, 2254, 2398, 2652], 'reviewed': [339, 428], 'each': [341, 848, 1372], 'abstract': [342], 'segregated': [343], 'a': [345, 371, 379, 589, 635, 698, 844, 912, 931, 943, 1011, 1084, 1122, 1216, 1243, 1495, 1631, 1665, 1705, 1765, 1772, 1814, 1892, 2173, 2183, 2297, 2345, 2465, 2473, 2524, 2527, 2546, 2564, 2609, 2642, 2675, 2706, 3224, 3266, 3354, 3405, 3525, 3579, 3635, 3734, 3763, 3836, 3855, 4046, 4074, 4083, 4158], 'topic': [347], 'area.': [348], 'Exclusions': [349], 'case': [351, 745], 'reports,': [352], 'basic': [353], 'science,': [354], 'secondary': [355], 'reflux,': [356, 1297, 1639], 'review': [357, 733], 'not': [360, 482, 860, 922, 1250, 1982, 2018, 2036, 2207, 2262, 2287, 2326, 2385, 2412, 2562, 2796, 3506, 3603, 4026, 4034, 4136, 4177], 'relevant.': [361], 'extracted': [363, 412, 432], 'article': [364], 'be': [366, 483, 979, 1010, 1038, 1172, 1200, 1340, 1367, 1480, 1494, 1524, 1618, 1630, 1651, 1985, 2149, 2170, 2304, 2323, 2403, 2413, 2431, 2456, 2599, 2729, 2783, 2817, 2907, 3312, 3383, 3394, 3432, 3576, 3623, 3692, 3806, 3815, 3854, 4056, 4157, 4171, 4194, 4228], 'accepted': [367], 'should': [368, 1120, 1523, 1663, 2906, 3311, 3691, 3783], 'assessed': [370, 1986, 2208], 'cohort': [372, 387], 'care': [381, 985, 1634, 1690, 3891], 'program': [382], 'that': [383, 1194, 1621, 1643, 1797, 1873, 2153, 2261, 2294, 2332, 2408, 2433, 2596, 2641, 2748, 2865, 3588, 3606, 4044, 4142], 'permitted': [384], 'identification': [385, 1091, 2362, 3142], 'outcomes.': [390, 2868, 3164], 'reporting': [392], 'meta-analysis': [394, 447, 758], 'observational': [396, 3976], 'studies': [397, 743, 1994, 2180, 2222, 2350, 2376, 3232, 3938, 3972], 'elaborated': [398], 'MOOSE': [401], '(Meta-analysis': [402], 'Of': [403], 'Observational': [404, 3419], 'Studies': [405], 'Epidemiology)': [407], 'group': [408, 2227], 'followed.': [410], 'analyzed': [415], 'formulated': [417], 'evidence-based': [419], 'recommendations.': [420, 3901], 'Results:': [421], 'A': [422, 730, 884, 905, 1167, 1454, 4090], 'total': [423], '2,028': [425], '131': [434], 'articles.': [435], 'Data': [436, 1795], '17,972': [438], 'included': [441, 901, 2223, 2236, 2241], 'analysis.': [444], 'systematic': [446], 'identified': [448, 2550, 2698, 2725], 'increasing': [449, 455], 'frequency': [450, 1532], 'urinary': [452, 1331, 1531, 3678], 'tract': [453, 1332, 1883, 1887], 'infection,': [454, 1159], 'grade': [456, 2237, 2242, 2662, 3566, 3797, 3812, 3989, 4067, 4109], 'presence': [461, 570, 1203, 1382, 1875, 2341, 2607, 2915, 2922, 4166], 'unique': [468], 'risk': [469, 542, 582, 1600, 1761, 1788, 1880, 2230, 2486, 2631, 2789, 2810, 2957, 3331, 3596, 3689, 4085], 'factors': [470, 3584, 3690, 3826, 4183], 'renal': [472, 547, 1024, 1048, 1069, 1077, 1107, 1142, 1207, 1253, 1260, 1271, 1304, 1320, 1325, 1337, 1603, 1733, 1790, 1845, 1929, 1945, 2127, 2232, 2477, 2591, 2613, 2636, 2745, 2924, 3453, 3609, 3684, 3737, 3911, 4130, 4146, 4162, 4189], 'cortical': [473, 1143, 1208, 1272, 1850, 1946, 2614, 3454], 'scarring.': [474, 2488, 3916], 'efficacy': [476, 2140], 'continuous': [478, 1961], 'antibiotic': [479, 1964, 3080, 3427], 'prophylaxis': [480], 'could': [481], 'current': [486], 'data.': [487], 'However,': [488, 2315, 3518], 'its': [489, 709, 2812, 4017], 'purported': [490], 'lack': [491, 616, 2138], 'efficacy,': [493], 'reported': [495], 'selected': [497, 1900], 'prospective': [498, 619, 3519], 'trials,': [500], 'also': [501, 585, 1020, 2430], 'is': [502, 886, 917, 942, 947, 1034, 1092, 1153, 1192, 1222, 1236, 1256, 1333, 1463, 1477, 1485, 1511, 1565, 1753, 1813, 2164, 2440, 2491, 2510, 2532, 2569, 2581, 2681, 2697, 2724, 2739, 2756, 2947, 2967, 2989, 3009, 3019, 3033, 3134, 3244, 3249, 3258, 3305, 3318, 3336, 3387, 3496, 3505, 3516, 3645, 3650, 3673, 3750, 3759, 3771, 3831, 3885, 3904, 3926, 3964, 3978, 4002, 4009, 4020, 4025, 4049, 4118, 4148, 4176], 'unproven': [503], 'owing': [504], 'significant': [506, 2446], 'limitations': [507], 'these': [509, 627, 651, 871, 2167, 2179, 2257, 3582, 3879, 4069], 'studies.': [510], 'resolution': [512, 1958, 2099, 2880, 2984, 3075, 3088, 3128, 3515, 3782, 3949, 4079], 'endoscopic': [514, 3007, 3098, 3112, 3494, 3620], 'surgical': [515, 1975, 2101, 3130, 3254, 3539, 3589], 'success': [516], 'rates': [517, 3946], 'are': [518, 559, 584, 836, 873, 900, 993, 1065, 1081, 1145, 1164, 1364, 1378, 1400, 1467, 1724, 1856, 2157, 2604, 2770, 2795, 2800, 2849, 3152, 3166, 3194, 3261, 3698, 3825, 4012, 4033, 4041], 'dependent': [519], 'upon': [520], 'then': [527], 'structured': [528], 'based': [535, 563, 580, 1754, 2533, 2785, 2908, 2948, 3577], 'goals': [538, 1717], 'minimizing': [540, 550], 'acute': [544, 1810, 1915, 2588, 2886, 2903], 'infection': [545, 1767, 1777, 1884, 2619, 2634, 3679, 3729], 'injury,': [548, 1734, 2592, 2746, 4190], 'while': [549, 1955, 3334], 'morbidity': [552, 1739, 2447, 2537, 2887], 'testing': [554], 'management.': [556, 2145, 4038], 'These': [557, 1079, 1870, 1889, 2129, 2146, 2291, 2869, 3204, 3659], 'age': [565, 2484, 2520, 2691, 2718, 3289, 3403, 3441, 3556, 4062], 'well': [567, 688, 1051, 1136, 1447, 2757, 3821], 'Recommendations': [576], 'long-term': [578, 1016], 'followup': [579, 2196, 3671, 3792, 3799, 3819, 3863, 3877, 3997, 4007, 4047], 'level': [583], 'included.': [586], 'Conclusions:': [587], 'Using': [588], 'structured,': [590], 'formal': [591, 3201], 'meta-analytic': [592], 'technique': [593], 'rigorous': [595], 'selection,': [597], 'conditioning': [598], 'quality': [600, 954], 'assessment,': [601], 'we': [602, 1405], 'attempted': [603, 1996], 'structure': [605, 1321], 'clinically': [606, 1496, 3657, 3676], 'managing': [610], 'children.': [614, 673, 1111, 1517], 'robust': [618], 'randomized': [620, 2106, 3520], 'controlled': [621, 2107, 3521], 'trials': [622, 2108, 3522], 'limits': [623], 'strength': [625, 952], 'but': [629, 1089, 1992, 2015, 3017, 3173, 3272, 3358, 3696, 3809], 'they': [630], 'can': [631, 1262, 1339, 2169, 2598, 4156, 4170, 4193], 'serve': [632, 4101], 'provide': [634, 843, 1242, 1264, 1891, 3784], 'framework': [636], 'set': [640], 'boundaries': [641], 'safe': [643, 2308], 'effective': [645], 'practice.': [646], 'As': [647], 'new': [648], 'emerge,': [650], 'will': [653, 2455], 'necessarily': [654], 'evolve.': [655], 'In': [656, 969, 2176, 2671, 2702, 3502], '1997': [657, 703, 1989], 'published': [662, 841], 'There': [674, 3151, 3165, 3193, 3216, 3260, 3830], 'has': [675, 907, 938, 1959, 2561, 3217, 3602, 3654, 3873], 'been': [676, 1960, 2132, 2327, 3218, 3604, 3655, 4137], 'an': [677, 1054, 1176, 1302, 1835, 2305, 2483, 2765, 2772, 2787, 3384, 3497, 3846, 3882, 3975, 3984, 4004], 'expanding': [678], 'body': [679], 'literature': [681, 731], 'evaluation': [684, 780, 1126, 1529, 4117], 'management,': [686, 1500], 'reflux.': [693, 2244], 'Therefore,': [694, 1112, 1404, 2489, 3132, 4211], 'appointed': [697], 'document': [704, 819], 'elected': [706], 'expand': [708], 'scope': [710], 'include': [712, 1072, 1275, 1292, 1569, 1664, 2339, 2870, 3176, 3276, 3714], 'siblings': [718, 801], 'VUR': [722, 1006, 1008, 1097, 1119, 1315, 1363, 1376, 1564, 1662, 1715, 1723, 1752, 1758, 1785, 1862, 1877, 1920, 1925, 1954, 1990, 2031, 2097, 2144, 2266, 2300, 2361, 2372, 2383, 2522, 2549, 2666, 2693, 2720, 2738, 2769, 2781, 2836, 2841, 2920, 2933, 2946, 2964, 3123, 3163, 3227, 3257, 3326, 3352, 3378, 3410, 3443, 3471, 3512, 3542, 3592, 3631, 3644, 3649, 3872, 3956, 3991, 4001, 4066, 4111, 4134, 4204, 4225], 'neonates/infants': [725], 'prenatally': [727, 2623], 'hydronephrosis.': [729, 817], 'search,': [732], 'extraction': [739], 'series': [746], 'performed': [748], '(see': [749, 998, 3279], 'technical': [750], 'chapters': [751, 840], 'online': [752, 842], 'at': [753, 1820, 2228, 3499, 4229], 'http://www.auanet.org/content/guidelines-and-quality-care/clinical-guidelines.cfm).': [754, 999], 'Extracted': [755], 'underwent': [757], 'determine': [760, 3308], 'outcomes': [762, 1377, 3234], 'related': [763, 1562, 1854, 2485, 3155, 4129], '1)': [769, 1726, 2955], 'VUR,': [778, 786, 792, 807, 1672, 1677, 1833, 2882, 3490, 3615, 3798], '2)': [779, 1731, 2979], 'infants': [784, 814, 2755], '3)': [787, 1736, 3001], 'dysfunction,': [797], '4)': [798, 3027], 'offspring': [803], '5)': [809], 'neonates': [812], 'prenatal': [816, 2555], 'statements': [823, 872], 'first': [826], 'sections': [828], 'derived': [829], 'meta-analysis.': [832], 'presented': [837, 1802], 'separately.': [838], 'Additional': [839], 'detailed': [845], 'summary': [846], 'topic.': [849], 'expert': [854], 'opinion': [855], 'when': [856, 945, 1509, 1583, 1701, 1764, 1792, 3924], 'explicit': [857], 'available,': [861, 1226, 3186], 'drafted': [864], 'statements.': [866], 'According': [867], 'definitions,': [870], 'graded': [874], 'respect': [876], 'degree': [879, 1268, 2806], 'flexibility': [881], 'application.': [883], '“standard”': [885], 'most': [888, 940, 1224, 1287, 1949, 2177, 2356, 2654, 3509], 'rigid': [889], 'treatment': [890, 1682, 1702, 1741, 1748, 2295, 3148, 3169, 3190, 3246, 3268, 3274, 3296, 3304, 3310, 3388], 'policy': [891], 'and,': [892], 'given': [893], 'limited': [894, 1237, 1284, 3219], 'definitive': [895, 973, 1644], 'data,': [896], 'only': [897, 2186, 2198, 2234], 'standards': [899], 'document.': [904], '“recommendation”': [906], 'significantly': [908], 'less': [909, 2457, 2515, 2686, 2713, 2990, 3010], 'rigidity,': [910], 'being': [911, 965, 1239, 3339, 3979, 4027], 'statement': [913, 944], 'there': [916, 946, 1812, 2189, 2799, 3018, 3697, 4011, 4040], 'sufficient': [918], 'evidence,': [919], 'even': [920, 1416], 'if': [921, 1140, 1417, 2166, 3185, 3768, 3870, 4023, 4180], 'consistently': [923], 'highest': [926], 'quality,': [927], 'advocate': [929], 'particular': [932], 'approach.': [934], 'An': [935, 2001], '“option,”': [936], 'flexibility,': [941], 'relatively': [950], 'equal': [951], 'supporting': [955], 'more': [956, 1857, 2335, 2441, 2445, 2498, 3287, 3688, 3694, 3993], 'approach,': [959], 'any': [961, 1747, 3253, 3914], 'approaches': [964], 'acceptable': [966, 2306], 'justifiable.': [968], 'absence': [971, 1205, 1384, 2673, 2704, 3413, 3446], 'stronger': [975], 'cannot': [977, 1617, 2148], 'appropriately': [978], 'made': [980, 2004, 2818], 'decisions': [982, 1213, 1577], 'regarding': [983, 1266, 1578, 1661], 'reside': [986], 'physician': [989, 3892], 'family.': [991], 'Definitions': [992], 'available': [994], 'Appendix': [997], 'Initial': [1000, 1709], 'Evaluation': [1001, 1095], 'Child': [1004, 1713, 2366, 2828, 3629], 'While': [1007, 4006], 'may': [1009, 1019, 1100, 1171, 1249, 1318, 1586, 1650, 2303, 2322, 2333, 2351, 2411, 2728, 2782, 3206, 3393, 3431, 3550, 3622, 3805, 3814, 4055, 4100, 4227], 'benign': [1012], 'condition': [1013], 'few': [1015, 3153, 3231], 'sequelae,': [1017], 'it': [1018, 1191, 2163, 2490, 3133, 3601, 3653, 3813], 'produce': [1021], 'end': [1022], 'stage': [1023], 'failure.': [1025], 'At': [1026, 1188], 'initial': [1027, 1114, 1189, 1211, 1528, 3500], 'presentation': [1028, 1115, 1190], 'nature': [1030], 'severity': [1033], 'unknown': [1035], 'must': [1037, 1568, 2267, 2402, 2429, 3575], 'documented.': [1039], 'strategy': [1041, 2944], 'focuses': [1042], 'attention': [1043], 'potential': [1047, 1490, 1673, 2466, 2630], 'impairment,': [1049], 'providing': [1053], 'important': [1055, 1497, 3135, 4149], 'baseline': [1056, 1168, 1217, 1936], 'future': [1058, 1184, 1219], 'comparisons.': [1059], 'somatic': [1061, 3717], 'effects': [1062, 1080], 'generally': [1066, 3593], 'linked': [1067, 1370], 'scarring,': [1070], 'hypertension,': [1073], 'growth': [1074, 3912, 4147, 4155], 'impairment': [1075], 'insufficiency.': [1078], 'present': [1082, 3337], 'small': [1085, 2249], 'number': [1086, 2391, 3969], 'early': [1090, 3681], 'important.': [1093, 1464], 'General': [1094, 3740, 3875], '“Standard:': [1096, 1518, 1656], 'UTI': [1099, 1317, 1805, 1827, 1937, 2009, 2014, 2027, 2039, 2058, 2077, 2125, 2216, 2275, 2540, 2743, 2751, 2791, 2834, 2890, 2960, 3032, 3051, 3105, 3333, 3357, 3408, 3473], 'detrimentally': [1101], 'affect': [1102, 1319, 3551], 'overall': [1104, 2942, 3637, 3968], 'health': [1105, 3558, 3638, 3718, 4163], 'function': [1108], 'affected': [1110, 1379], 'child': [1117, 1504, 1637, 1721, 1780, 2298, 2435, 2514, 2547, 2685, 2712, 2844, 2856, 2896, 3322, 3346, 3372, 3398, 3436, 3463], 'undergo': [1121], 'careful': [1123, 1455], 'general': [1124, 1414, 3503], 'medical': [1125, 1951, 3876], 'measurement': [1128], 'height,': [1130], 'weight': [1131, 3749], 'blood': [1133, 3720, 3745], 'pressure,': [1134, 3746], 'serum': [1138, 1169], 'creatinine': [1139, 1170], 'bilateral': [1141], 'abnormalities': [1144, 1209, 1443, 1851, 2615, 3455], 'found.”': [1146], '“Recommendation:': [1147, 1313, 2508, 2670, 3238, 3316, 3739, 3753, 3902], 'Urinalysis': [1148, 3754], 'proteinuria': [1150, 3732, 3756], 'bacteriuria': [1152, 3758], 'recommended.': [1154], 'If': [1155, 3239, 3974], 'urinalysis': [1157, 3725, 3770], 'indicates': [1158], 'urine': [1160, 3764], 'culture': [1161, 3765], 'sensitivity': [1163, 3767], 'recommended.”': [1165, 1334], '“Option:': [1166, 1335, 2701, 2774, 3391, 3418, 3611, 4052, 4089], 'obtained': [1173, 1341], 'establish': [1175, 4103], 'estimate': [1177], 'glomerular': [1179], 'filtration': [1180], 'rate': [1181, 1774, 1816, 2981, 3003, 3029, 3076, 4076], '(GFR)': [1182], 'reference.”': [1185], 'Imaging': [1186], 'Procedures': [1187], 'recommended': [1193, 2511, 2682, 3306, 3319, 3751, 3905, 3927], 'status': [1196, 1345, 3562, 3641], 'kidneys': [1199, 1348, 4126], 'assessed.': [1201], 'guides': [1210], 'establishes': [1215], 'decisions.': [1220], 'Ultrasound': [1221], 'widely': [1225], 'inexpensive': [1227], 'radiation-free': [1229], 'means': [1230, 2213], 'obtain': [1232], 'information.': [1234], 'It': [1235, 1484, 2428, 4175], 'unable': [1240], 'quantitative': [1244], 'assessment': [1245, 1390, 1684, 2192, 4144], 'relative': [1247], 'function,': [1248, 1323, 1361], 'detect': [1251], 'scarring': [1254, 1291, 1350, 1791, 1819, 1913, 2478, 2925, 4131, 4169], 'operator': [1257], 'dependent.': [1258], 'DMSA': [1259, 1336, 1807, 1944, 4191, 4201, 4218], 'imaging': [1261, 1338, 1579, 3791, 3971, 3998], 'better': [1263, 2352], 'information': [1265, 1616, 1627], 'abnormalities.': [1273, 1947], 'Limitations': [1274], 'expense,': [1276], 'radiation': [1277], 'exposure,': [1278], 'possible': [1279, 1409, 2020, 3273], 'need': [1280, 2815, 4114, 4121], 'sedation': [1282], 'availability.': [1285], 'Those': [1286], 'likely': [1288, 1686, 2357, 2442, 3994, 4035], 'grades': [1295, 2224, 2425, 2694, 2721, 3469, 3954], 'III–V': [1296, 2695], 'younger': [1298, 2394, 2418, 2436, 2506, 2648, 2857], 'children,': [1299, 2161, 3664], 'abnormal': [1303, 1478], 'ultrasound': [1305, 1326], 'study': [1306, 1941, 2252], 'recurrent': [1310, 2539, 3449, 4087], 'febrile': [1311, 1729, 1776, 1804, 2008, 2124, 2274, 2528, 2678, 2709, 2742, 2889, 2959, 3050, 3450, 3531, 3598], 'UTIs.': [1312], 'Because': [1314], 'performing': [1324], 'assess': [1328, 1343], 'upper': [1330, 1882, 1886], 'function.”': [1352], 'Assessment': [1353], 'Voiding': [1355, 3917], 'Patterns': [1356], 'Abnormal': [1357], 'recognized': [1365, 2432], 'associated': [1368, 2502], 'other': [1373], 'UTI.': [1375, 2348, 2529], 'BBD.': [1386, 3150], 'terminology': [1388], 'various': [1393, 3583], 'manifestations': [1394], 'unsettled': [1401], 'complex.': [1403], 'used': [1406], 'broadest': [1408], 'approach': [1410, 1585, 2309, 2531, 2644, 3712, 3977], 'capture': [1412], 'relationship,': [1415], 'associations': [1419], 'remain': [1420], 'undocumented,': [1421], 'emphasizing': [1422], 'importance': [1424, 1614], 'understanding': [1432], 'VUR.': [1434, 1784, 2427, 3794, 4153], 'term': [1436], 'refers': [1441], 'storage': [1445], 'emptying,': [1449], 'often': [1451], 'includes': [1452], 'constipation.1': [1453], 'inquiry': [1456], 'signs': [1458, 3682], 'symptoms': [1460, 2900], 'BBD': [1462, 1492, 1510, 1522, 2343, 2931, 2939, 2976, 2998, 3016, 3042, 3058, 3117, 3138, 3161, 3172, 3222, 3236, 3243, 3248, 3303, 3324, 3335, 3360, 3381, 3415, 3477, 3480, 3959], 'Many': [1465], 'parents': [1466, 2814], 'unaware': [1468], 'their': [1470, 2461], "child's": [1471, 3636], 'toileting': [1472], 'patterns': [1473, 3139], 'consider': [1475, 1488], 'what': [1476], 'normal': [1481, 4092], 'routine.': [1483], 'appropriate': [1486, 2324, 3507], 'factor': [1498, 3225], 'throughout': [1499], 'particularly': [1501, 1582, 4021], 'moves': [1505], 'through': [1506, 2551, 2575, 2699, 2726], 'toilet': [1507], 'training': [1508, 3178], 'thought': [1512, 2640, 4141], 'emerge': [1514], 'many': [1516], 'Symptoms': [1519], 'indicative': [1520], 'sought': [1525], '(including': [1530], 'urgency,': [1534], 'prolonged': [1535, 3865], 'voiding': [1536, 2194, 4093], 'intervals,': [1537], 'daytime': [1538], 'wetting,': [1539], 'perineal/penile': [1540], 'pain,': [1541], 'holding': [1542], 'maneuvers': [1543], '[posturing': [1544], 'prevent': [1546, 1727, 1732, 2587, 2741], 'wetting]': [1547], 'constipation/encopresis).”': [1549], 'Family': [1550, 1657], 'Patient': [1552], 'Education': [1553], 'Involvement': [1554], 'family': [1557], 'decision': [1560, 3574], 'making': [1561], 'critical,': [1566], 'balanced': [1570], 'objective': [1572], 'education': [1573, 1660], 'permit': [1575, 2334, 2583, 2824, 3141], 'informed': [1576, 2825], 'therapy,': [1581], 'one': [1584, 2517, 2688, 2715, 3400, 3438, 4059], 'no': [1588, 2113, 2191, 3020, 3167, 3195, 3380, 3699, 4013, 4042, 4096], 'demonstrable': [1589], 'benefit': [1590, 2114, 2359], 'advantage': [1592], 'over': [1593, 3399, 3437, 3708], 'another.': [1594, 3709], 'Given': [1595], 'potential,': [1597], 'although': [1598, 3600], 'uncertain,': [1599], 'severe': [1602], 'injury': [1604], 'lifelong': [1606], 'consequences': [1607, 1674], 'some': [1611, 1654, 2211, 2584], 'patients,': [1612], 'overestimated.': [1619], 'For': [1620, 2545, 3795, 3986], 'reason': [1622], 'considers': [1625, 3365], 'transfer': [1628], 'standard': [1632], 'recognition': [1642, 2407, 3220, 3587], 'guidance': [1645, 3785], 'optimal': [1648], 'therapy': [1649, 1898, 1952, 2338, 3008, 3278, 3428, 3488], 'lacking': [1652], 'areas.': [1655], 'patient': [1659, 2246, 2354, 2647, 2918], 'discussion': [1666, 2759], 'rationale': [1669, 1745, 1893, 2936, 3833], 'treating': [1671, 1719, 3160], 'untreated': [1676], 'equivalency': [1679], 'certain': [1681], 'approaches,': [1683], 'adherence': [1687], 'plan,': [1691], 'determination': [1692], 'parental': [1694, 1699, 2927, 3570, 3823], 'concerns': [1695], 'accommodation': [1697], 'preferences': [1700], 'choices': [1703], 'offer': [1704, 2497], 'similar': [1706], 'risk-benefit': [1707], 'balance.”': [1708], 'recurring': [1728], 'UTIs,': [1730, 3126, 3451, 3599], 'minimize': [1737], 'followup.': [1743], 'several': [1756, 2862], 'assumptions.': [1757], 'increases': [1759, 1786, 1878], 'pyelonephritis': [1763, 1793, 1811, 1916], 'occurs,': [1768], 'evidenced': [1770], 'higher': [1773, 1815, 2474, 2665, 3953], 'develops.': [1794], 'demonstrate': [1796], 'who': [1800, 1863, 2560, 2696, 2723, 2794, 3535, 4226], 'documentation': [1808], 'permanent': [1818], 'least': [1821], '6': [1822, 2052, 2055], 'months': [1823, 2986, 3804, 3840, 3851, 3908, 3932], 'after': [1824, 1914, 2987, 4058], 'odds': [1836, 1907], 'ratio': [1837], '2.8': [1839], '3.7': [1843], 'units': [1846], '(fig.': [1847, 1868, 2977, 2999, 3025, 3043], '1).': [1848, 2022], 'Renal': [1849, 4154], '(ie': [1852], 'scarring)': [1855], 'frequent': [1858], 'had': [1865, 2182, 2472, 2563], 'previous': [1866, 3843], 'UTIs': [1867, 3532], '2).': [1869], 'indicate': [1872, 2260, 2293, 2902], 'damage.': [1888], 'observations': [1890, 2951, 3205], 'preventive': [1895, 2155], 'curative': [1897, 3094, 3487], 'Figure': [1902, 1932, 2071, 2270, 3045, 3069, 3082, 3100], '1.': [1903, 2024], 'Forest': [1904, 3047, 3071, 3084, 3102], 'plots': [1905, 3048, 3072, 3085, 3103], 'ratios': [1908], 'log': [1910], 'scale': [1911], 'among': [1917, 3077], 'compared': [1921, 3543], '(A)': [1926, 2276], 'unit': [1930], '(B).': [1931], '2.': [1933, 3459], 'Relationship': [1934], 'between': [1935, 2007, 3936], 'incidence': [1938, 2078, 2122, 2475, 2611, 2752, 3052, 3106], 'different': [1940, 2851], 'populations': [1942], 'common': [1950, 3174], 'awaiting': [1956], 'spontaneous': [1957, 2879, 3127, 3514, 3948, 3995, 4078], 'low': [1962, 3811, 4084], 'dose': [1963], 'prophylaxis.': [1965, 3081], 'IRSC': [1967], 'demonstrated': [1968], 'equivalence': [1969], 'CAP': [1971, 1980, 2033, 2038, 2042, 2048, 2093, 2116, 2142, 2205, 2284, 2289, 2302, 2381, 2509, 2568, 2597, 2658, 2680, 2966, 3317, 3343, 3369, 3392, 3474, 3869, 4024], '(medical': [1972, 3055], 'therapy)': [1973], 'therapy.2,3': [1976], 'use': [1978, 2379, 2566, 3062, 3367, 3486, 3866, 4216], 'able': [1983, 2458], 'recent': [1993], 'address': [1998], 'question.': [2000], 'attempt': [2002], 'differentiate': [2006], 'cystitis,': [2011], 'nonfebrile': [2013], 'always': [2019], '(table': [2021], 'Table': [2023, 3458], 'Rates': [2025], 'receiving': [2032, 2037, 2283, 2288, 3079, 3546], 'No.': [2040, 2045], '%': [2041, 2046], '(95%': [2043, 2049], 'CI)': [2044, 2050], 'No': [2047, 3476], 'Cystitis': [2051], '7.2': [2053], '(2.3,20.3)': [2054], '7.9(2.1,26.1)': [2056], 'Febrile': [2057], '11': [2059], '15.2': [2060], '(9.1,24.2)': [2061], '8': [2062], '6.1(2.3,15.0)': [2063], 'Not': [2064], 'specified': [2065], '18': [2066], '19.0': [2067], '(13.3,26.3)': [2068], '7': [2069], '17.8(8.6,33.3)': [2070], 'shows': [2073], 'distribution': [2075], 'CAP.': [2084, 2269, 3390, 3547], 'finding': [2086], 'challenges': [2087], 'long-standing': [2089], 'convention': [2090], 'using': [2092], 'until': [2098, 3228, 3647], 'cure.': [2102, 3131], 'Several': [2103], 'large,': [2104], 'prospective,': [2105], 'shown': [2110, 3524], 'little': [2111, 3832], 'terms': [2118], 'reducing': [2120], 'scarring.4–6': [2128], 'broadly': [2133], 'interpreted': [2134, 2150], '“proving”': [2136], 'mean': [2152], 'modern': [2154], 'measures': [2156], 'useless': [2158], 'uncertain': [2165], 'conclusions': [2168, 2410, 3210], 'generalized': [2171], 'broader': [2174], 'population.': [2175], 'history': [2184, 2346, 2525, 2676, 2707, 3355, 3406], 'UTI,': [2188, 2565, 2679, 2710, 3430], 'patterns,': [2195], 'years,': [2202], 'compliance': [2203], 'diagnosing': [2215], 'imperfect.': [2218], 'Most': [2219], 'I–III': [2225], '(a': [2226], 'lower': [2229, 2883, 3945], 'scarring),': [2233], 'IV': [2238], 'none': [2240], 'V': [2243], 'Overall': [2245], 'numbers': [2247], 'individual': [2251], 'power': [2253], 'limited.': [2255], 'Nonetheless,': [2256], 'clearly': [2259], '3.': [2271], 'Incidence': [2272], 'cystitis': [2278], '(B)': [2279], '(filled)': [2285], '(open)': [2290], 'proper': [2312], 'setting.': [2314], 'criteria': [2318], 'definitively': [2328], 'determined.': [2329], 'Clinical': [2330], 'parameters': [2331], 'selectivity': [2336], 'Future': [2349], 'identify': [2353, 3137, 3675, 4000], 'subgroups': [2355], 'treatment.': [2364], 'Younger': [2367, 2470], 'Than': [2368, 2830], 'Year': [2370, 2832], 'With': [2371, 2833], 'Outcomes': [2373], 'stratified': [2386, 3233], 'age,': [2388, 2919], 'small.': [2399], 'viewed': [2404], 'fully': [2414], 'validated': [2415], 'nor': [2422], 'suffer': [2444], 'APN': [2449, 2503], 'child,': [2453, 3561], 'communicate': [2460], 'symptoms,': [2462], 'leading': [2463], 'delay': [2467], 'diagnosis.': [2469, 3501], 'suggesting': [2482], 'considered': [2492, 2771, 2784, 3395, 3433, 4003], 'reasonable': [2493, 3856], 'prudent': [2495, 3711], 'protection': [2499], 'against': [2500], 'child.': [2507], 'greater': [2536, 2610, 2872, 2892, 2968, 3034, 4186], 'found': [2541], 'population.”': [2544], 'due': [2553, 3327], 'hydronephrosis': [2556], 'sibling': [2558, 2626], 'controversial': [2570], 'difficult': [2572], 'support': [2574, 3705, 4016], 'evidence.': [2576], 'intention': [2578], 'measure': [2585], 'illness': [2589], 'yet': [2593], 'presumes': [2595], 'effective.': [2600], 'Although': [2601, 2798], 'imperfect,': [2605], 'following': [2618, 3006, 3109], 'detected': [2622, 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