Publication Information

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359, 398, 463], 'authorNeal': [91, 282], 'Castagnoli': [92, 95, 283, 286, 596, 623, 1171, 1424, 1559, 1623, 1687, 1745], 'Jr.,': [93, 284], 'Neal': [94, 285], 'Jr.': [96, 287], 'authorRona': [130, 321], 'R.': [131, 134, 322, 325, 482, 552, 568, 645, 734, 764, 773, 791, 798, 871, 909, 978, 1061, 1138, 1249, 1273, 1308, 1344, 1373, 1584, 1710, 1716], 'Ramsay,': [132, 323], 'Rona': [133, 324], 'Ramsay': [135, 326, 977, 1248, 1272, 1307, 1343, 1372], 'authorAnthony': [169, 360], 'J.': [170, 173, 361, 364, 479, 529, 553, 567, 824, 839, 848, 868, 903, 940, 943, 949, 972, 998, 1004, 1009, 1030, 1052, 1055, 1108, 1192, 1198, 1267, 1276, 1311, 1376, 1419, 1494, 1521, 1529, 1557, 1565, 1577, 1585, 1616, 1701], 'Trevor,': [171, 362], 'Anthony': [172, 363], 'Trevor': [174, 365, 593, 619, 1166, 1348, 1428, 1563, 1620, 1676, 1741], 'author': [208, 399], 'First': [400], 'published:': [401], 'July': [402], '1987': [403], 'https://doi.org/10.1111/j.1471-4159.1987.tb03384.xCitations:': [404], '205Read': [405], 'full': [407, 418], 'textAboutPDF': [408], 'ToolsRequest': [409], 'permissionExport': [410], 'citationAdd': [411], 'favoritesTrack': [413], 'citation': [414], 'ShareShare': [415], 'Give': [416], 'accessShare': [417, 420], 'text': [419], 'full-text': [421, 436, 460], 'accessPlease': [422], 'review': [423], 'our': [424], 'Terms': [425, 448], 'Conditions': [427, 450], 'Use': [429], 'check': [431], 'box': [432], 'below': [433, 456], 'share': [435, 458], 'version': [437, 461], 'article.I': [439], 'have': [440], 'read': [441], 'accept': [443], 'Wiley': [445], 'Online': [446], 'Library': [447], 'UseShareable': [452], 'LinkUse': [453], 'link': [455], 'a': [459, 474, 631, 859, 1021, 1071, 1150, 1486, 1490, 1513, 1636], 'article': [464], 'with': [465, 1573, 1601, 1754], 'your': [466], 'friends': [467], 'colleagues.': [469], 'Learn': [470], 'more.Copy': [471], 'URL': [472], 'Share': [473], 'linkShare': [475], 'onEmailFacebookTwitterLinkedInRedditWechat': [476], 'References': [477], 'Baker': [478], 'K.,': [480, 592, 618, 976, 1169, 1379, 1382, 1463, 1680, 1740], 'Borne': [481], 'R.,': [483, 735, 979, 1250, 1274, 1309, 1345, 1374, 1390], 'Davis': [484], 'M.': [485, 545, 572, 674, 680, 708, 712, 975, 1065, 1381], 'M.,': [486, 541, 875, 947, 1088, 1460, 1711, 1714, 1717], 'Waters': [488], 'I.': [489, 845, 1013], 'W.': [490, 794, 849, 1132, 1507, 1721], '(1984)': [491, 599, 775, 1041, 1067, 1117, 1430], 'Metabolism': [492, 600, 748, 1691], '1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine': [494, 1479, 1518, 1545, 1572, 1606, 1696], '(MPTP)': [495, 716, 1437, 1607], 'mouse': [497], 'liver': [498, 585, 755, 1698], 'preparations.': [499, 586], 'Biochem.': [500, 611, 638, 693, 727, 1211, 1242, 1301, 1337, 1412, 1452, 1547, 1576], 'Biophys.': [501, 612, 639, 694, 728, 1212, 1243, 1302, 1338, 1413, 1453, 1548], 'Res.': [502, 613, 640, 695, 729, 1213, 1244, 1303, 1339, 1414, 1454, 1549], 'Commun.': [503, 614, 641, 696, 730, 1214, 1245, 1304, 1340, 1415, 1455, 1550], '125,': [504, 1456], '484–490.': [505], 'Beinert': [506], 'H.,': [507], 'Palmer': [508], 'G.,': [509, 677, 706], 'Cremona': [510], 'T.,': [511, 741, 970, 1385], '(1965)': [516], 'Kinetic': [517], 'studies': [518, 684], 'on': [519, 685, 1176, 1400, 1608], 'reduced': [520], 'diphosphopyridine': [521], 'nucleotide': [522], 'dehydrogenase': [523, 1324, 1405], 'electron': [525], 'paramagnetic': [526], 'resonance': [527], 'spectroscopy.': [528], 'Biol.': [530, 840, 999, 1268], 'Chem.': [531, 841, 1000, 1194, 1269, 1496, 1703], '240,': [532], '475–480.': [533], 'Bradbury': [534], 'A.': [535, 540, 620, 746, 969, 1066, 1091, 1201, 1223, 1349, 1384, 1387, 1429, 1564, 1621, 1657, 1677, 1742], 'J.,': [536, 621, 646, 795, 818, 872, 1084, 1133, 1218, 1220, 1314, 1347, 1350, 1502, 1622, 1675, 1678, 1743], 'Costall': [537], 'B.,': [538, 950, 1036], 'Domeney': [539], 'Jenner': [542], 'P.,': [543, 649, 821, 1007, 1053, 1423, 1527, 1555, 1685], 'Kelly': [544], 'E.,': [546, 765, 792, 973, 1082, 1388, 1504], 'Marsden': [547], 'C.': [548, 737, 774, 799, 906, 1058, 1501, 1656, 1720], 'D.,': [549, 672, 701, 944], 'Naylor': [551], '(1986)': [554, 573, 654, 984, 1255, 1471, 1566, 1748], '1-Methyl-4-phenylpyridine': [555, 956], 'is': [556, 1234], 'neurotoxic': [557, 603, 933, 1261, 1434, 1570, 1603, 1637], 'nigrostriatal': [560, 1189, 1694], 'dopamine': [561, 890, 1120, 1516], 'pathway.': [562], 'Nature': [563, 787, 1078, 1590], '319,': [564], '56–57.': [565], 'Cashman': [566], 'Zeigler': [570], 'D.': [571, 817, 1533, 1663], 'Contribution': [574], 'N-oxygenation': [576], 'metabolism': [579, 919], 'MPTP': [581, 752, 921, 1207, 1233], '(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)': [582], 'various': [584], 'Mol.': [587], 'Pharmacol.': [588, 1109, 1522, 1617], '29,': [589], '163–167.': [590], 'Chiba': [591, 617, 1168, 1679, 1739], 'A.,': [594, 704, 832, 869, 1162, 1167, 1683], 'N.': [597, 624, 740, 1172, 1425, 1560, 1624, 1688, 1746], 'Jr': [598, 625, 1173, 1689, 1747], 'tertiary': [604], 'amine,': [605], 'MPTP,': [606, 634], 'brain': [608, 636, 1146, 1361], 'monoamine': [609, 756, 784, 1182, 1439, 1542, 1574, 1724], 'oxidase.': [610], '120,': [615], '574–578.': [616], '(1985)': [626, 747, 800, 850, 880, 1092, 1140, 1174, 1202, 1224, 1508, 1534, 1586, 1598, 1690, 1722], 'Active': [627], 'uptake': [628, 884, 1099, 1257, 1357, 1409], 'MPP+,': [630], 'metabolite': [632, 662, 887, 1073, 1151, 1262], 'synaptosomes.': [637], '128,': [642, 1246], '1228–1232.': [643], "D'Amato": [644, 870, 1583], 'Lipman': [647], 'Z.': [648], 'Snyder': [651, 877], 'S.': [652, 703, 874, 878, 913, 953, 1040, 1465], 'H.': [653, 879, 946, 1581], 'Selectivity': [655], 'parkinsonian': [658], 'neurotoxin': [659, 751, 1154, 1286], 'MPTP:': [660, 1635], 'toxic': [661, 1492], 'MPP+': [663, 854], 'binds': [664], 'neuromelanin.': [666], 'Science': [667, 1026, 1048, 1128, 1733], '231,': [668], '987–989.': [669], 'Di': [670, 699], 'Monte': [671, 700], 'Sandy': [673, 707], 'S.,': [675, 709, 770, 910, 1062, 1165], 'Ekstrom': [676, 705], 'Smith': [679, 711], '(1986a)': [682, 1282], 'Comparative': [683], 'mechanisms': [687], 'paraquat': [689], '1-methyl-4-phenylpyridine': [691, 718, 1287], 'toxicity.': [692, 894], '137,': [697, 731], '303–309.': [698], 'Jewell': [702], '(1986b)': [714, 1319], '1-Methyl-4-phenyl-tetrahydropyridine': [715], '(MPP+)': [719, 809, 957, 1288], 'cause': [720, 1075], 'rapid': [721], 'ATP': [722], 'depletion': [723], 'isolated': [725], 'hepatocytes.': [726], '310–315.': [732], 'Fritz': [733], 'Abell': [736, 1719], 'W.,': [738, 743, 1005, 1010, 1031], 'Patel': [739], 'Gessner': [742], 'Brossi': [745], 'human': [754], 'oxidase': [757, 785, 1183, 1725], 'B.': [758], 'FEBS': [759], 'Lett.': [760, 813], '186,': [761], '224–227.': [762], 'Heikkila': [763, 790, 1137], 'Manzino': [766], 'L.,': [767, 1277, 1312, 1377], 'Cabbat': [768], 'F.': [769, 1469], 'Duvoisin': [772, 797], 'Protection': [776], 'against': [777, 1103], 'dopaminergic': [779], 'neurotoxicity': [780, 862, 1104, 1365], '1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine': [782], 'inhibitors.': [786], '311,': [788, 1079], '467–469.': [789], 'Nicklas': [793, 1131], 'Dopaminergic': [801], 'toxicity': [802], 'after': [803], 'stereotaxic': [804], 'administration': [805], '1-methyl-4-pyridiniumion': [808], 'rats.': [811], 'Neurosci.': [812], '59,': [814], '135–140.': [815], 'Morgan': [816], 'Casida': [823], 'E.': [825, 1035, 1139, 1594, 1737], '(1968)': [826], 'Binding': [827], 'sites': [828], 'rotenone,': [830], 'piericidin': [831], 'Amytal': [834], 'respiratory': [837], 'chain.': [838], '243,': [842], '834–843.': [843], 'Irwin': [844, 1012, 1032], 'Langston': [847, 1003, 1029, 1034], 'Selective': [851], 'accumulation': [852], 'substantia': [857, 1230], 'nigra:': [858], 'key': [860], 'Life': [863, 935, 964, 1156, 1368, 1757], 'Sci.': [864, 898, 936, 965, 1157, 1369, 1758], '36,': [865, 937, 1158], '207–212.': [866], 'Javitch': [867], 'Strittmatter': [873], 'Parkinsonism-inducing': [881], 'neurotoxin,': [882], 'N-methyM-phenyl-1,2,3,6-tetrahydropyridine:': [883], 'N-methyl-4-phenylpyridine': [888, 1359], 'neurons': [891, 1121, 1611], 'explains': [892], 'selective': [893], 'Proc.': [895], 'Natl.': [896], 'Acad.': [897], 'USA': [899], '82,': [900], '2173–2177.': [901], 'Johannessen': [902, 939, 1054], 'N.,': [904, 941, 1056, 1708], 'Chiueh': [905, 1057], 'C.,': [907, 1059, 1113, 1466], 'Burns': [908, 1060], 'Markey': [912, 952, 1051], '(1985a)': [915], 'Differences': [916], 'rodent': [924], 'primate': [926, 1731], 'parallel': [927], 'differences': [928], 'sensitivity': [930], 'its': [932, 1290, 1329], 'effects.': [934], '219–224.': [938], 'Adams': [942], 'Schuller': [945], 'Bacon': [948], '(1985b)': [955], 'induces': [958], 'oxidative': [959], 'stress': [960], 'rodent.': [963], '38,': [966], '743–749.': [967], 'Kowal': [968, 1383], 'Morningstar': [971], 'Johnson': [974, 1380, 1386], 'Spectroscopic': [985], 'characterization': [986, 1484], 'number': [989], 'type': [991], 'iron-sulfur': [993], 'clusters': [994], 'NADH-ubiquinone': [996], 'oxidoreductase.': [997], '261,': [1001, 1270], '9239–9245.': [1002], 'Ballard': [1006], 'Tetrud': [1008], '(1983)': [1014], 'Chronic': [1015], 'parkinsonism': [1016, 1045], 'humans': [1018], 'due': [1019], 'product': [1022, 1186], 'meperi-dine-analog': [1024], 'synthesis.': [1025], '219,': [1027], '979–980.': [1028], 'I.,': [1033, 1135, 1420, 1530, 1558], 'Forno': [1038], 'L.': [1039, 1161, 1459, 1470, 1662, 1682, 1713], 'Pargyline': [1042], 'prevents': [1043], 'MPTP-induced': [1044], 'primates.': [1047], '225,': [1049, 1129], '1480–1482.': [1050], 'Herkenham': [1064], 'Intra-neuronal': [1068], 'generation': [1069], 'pyridinium': [1072], 'may': [1074], 'drug-induced': [1076], 'parkinsonism.': [1077, 1336], '464–467.': [1080], 'Melamed': [1081], 'Rosenthal': [1083], 'Cohen': [1085, 1115], 'O.,': [1086], 'Globus': [1087], 'Uzzan': [1090], 'Dopamine': [1093], 'but': [1094], 'not': [1095], 'epinephrine': [1096], 'or': [1097], 'serotonin': [1098], 'inhibitors': [1100], 'protect': [1101], 'mice': [1102], 'MPTP.': [1106, 1191, 1367, 1451], 'Eur.': [1107, 1520, 1615], '116,': [1110], '179–181.': [1111], 'Mytilineou': [1112], 'G.': [1116, 1597, 1659], '1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine': [1118], 'destroys': [1119], 'explants': [1123], 'rat': [1125], 'embryo': [1126], 'mesencephalon.': [1127], '529–531.': [1130], 'Vyas': [1134], 'Inhibition': [1141, 1320], 'NADH-linked': [1143, 1297], 'oxidation': [1144, 1185], 'mitochondria': [1147, 1362], '1-methyl-4-phenylpyridine,': [1149], '1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.': [1155], '2503–2508.': [1159], 'Peterson': [1160, 1681], 'Caldera': [1163, 1684], 'Studies': [1175], '1-methyl-4-phenyl-2,3-dihydro-pyridinium': [1178], 'species': [1179, 1753], '2,3-MPDP+,': [1180], 'catalyzed': [1184], 'toxin': [1190, 1695], 'Med.': [1193, 1702], '28,': [1195, 1704], '1432–1436.': [1196], 'Poirier': [1197, 1217], 'Barbeau': [1200, 1222], 'A': [1203, 1441, 1726], 'catalyst': [1204], 'function': [1205], 'superoxide': [1209], 'formation.': [1210], '131,': [1215], '1284–1289.': [1216], 'Donaldson': [1219], 'The': [1225], 'specific': [1226], 'vulnerability': [1227], 'nigra': [1231], 'related': [1235], 'presence': [1238], 'transition': [1240], 'metals.': [1241], '25–33.': [1247], 'Energy-dependent': [1256], 'Af-methyl-4-phenylpyridinium,': [1259], '1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,': [1264], 'mitochondria.': [1266, 1411], '7585–7587.': [1271], 'Salach': [1275, 1310, 1375, 1418, 1528, 1556], 'Uptake': [1283], 'relation': [1291, 1331], 'inhibition': [1294, 1536], 'mitochondrial': [1296, 1322, 1401], 'substrates': [1298], 'MPP+.': [1300], '134,': [1305], '743–748.': [1306], 'Dadgar': [1313, 1346], 'NADH': [1323, 1404], 'pyridine': [1326, 1398], 'derivatives': [1327, 1399], 'possible': [1330], 'experimental': [1333], 'idiopathic': [1335], '135,': [1341], '269–275.': [1342], '(1986c)': [1355], 'Energy-driven': [1356], 'mediates': [1363], '39,': [1370, 1759], '581–588.': [1371], 'McKeown': [1378], 'Booth': [1389], '(1987)': [1395, 1630], 'Action': [1396], 'respiration': [1402], 'their': [1407], 'carrier-mediated': [1408], 'into': [1410], '(in': [1416], 'press).': [1417], 'Jr,': [1426, 1561, 1625], 'Oxidation': [1431], 'amine': [1435, 1571], '1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine': [1436], 'oxidases': [1440, 1543], 'B': [1443, 1728], 'suicide': [1445], 'inactivation': [1446, 1540], 'enzymes': [1449], '831–835.': [1457], 'Sayre': [1458], 'Arora': [1461], 'Feke': [1464], 'Urbach': [1468], 'Mechanism': [1472], 'induction': [1474], "Parkinson's": [1476, 1588], 'disease': [1477], '(MPTP).': [1480, 1546], 'Chemical': [1481], 'electrochemical': [1483], 'geminal-dimethyl-blocked': [1487], 'analogue': [1488], 'postulated': [1491], 'metabolite.': [1493], 'Am.': [1495], 'Soc.': [1497], '108,': [1498], '2464–2466.': [1499], 'Schmidt': [1500], 'Bruckwick': [1503], 'Lovenberg': [1506], 'Lack': [1509], 'evidence': [1511], 'supporting': [1512], 'role': [1514], 'neurotoxicity.': [1519], '113,': [1523], '149–150.': [1524], 'Crabtree': [1532], 'Reversible': [1535], 'mechanism-based': [1538], 'irreversible': [1539], '127,': [1551], '341–346.': [1552], 'Interactions': [1567, 1749], 'oxidases.': [1575], '235,': [1578], '785–789.': [1579], 'SnyderS.': [1580], 'Predicting': [1587], 'disease.': [1589], '317,': [1591], '198–199.': [1592], 'Sundstrom': [1593], 'Jonnson': [1596], 'Pharmacological': [1599], 'interference': [1600], 'actions': [1604], 'central': [1609], 'catecholaminergic': [1610], 'mouse.': [1614], '110,': [1618], '293–299.': [1619], 'Pharmacology': [1631, 1650], 'toxicology': [1633], 'by-product': [1638], 'illicit': [1640], 'designer': [1641], 'drug': [1642], 'chemistry,': [1643], 'Cocaine,': [1645], 'Marijuana,': [1646], 'Designer': [1647], 'Drugs:': [1648], 'Chemistry,': [1649], 'Behavior': [1652], '(': [1653], 'K.': [1654, 1707], 'Redda,': [1655], 'Walker,': [1658], 'Barnett,': [1660], 'Fannin),': [1664], 'press.': [1666], 'CRC': [1667], 'Press,': [1668], 'Boca': [1669], 'Raton': [1670], ',': [1671], 'Florida': [1672], '.': [1673], 'Weissman': [1674], 'homogenate': [1699], 'fractions.': [1700], '997–1001.': [1705], 'Westlund': [1706], 'Denney': [1709], 'Kochenperger': [1712], 'Rose': [1715], 'Distinct': [1723], 'populations': [1729], 'brain.': [1732], '230,': [1734], '181–183.': [1735], 'Wu': [1736], 'Y.,': [1738], '1-methyl-4-phenyl-2,3-dihydropyridinium': [1752], 'synthetic': [1755], 'dopamine-melanin.': [1756], '1695–1700.': [1760], 'Citing': [1761], 'Literature': [1762], 'Volume49,': [1763], 'Issue1July': [1764], '1987Pages': [1765], 'ReferencesRelatedInformation': [1767]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2126557788', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T23:43:22.603513', 'created_date': '2016-06-24'}