Publication Information

{'id': 'https://openalex.org/W2125209491', 'doi': 'https://doi.org/10.1177/1074248414568194', 'title': 'Effects of Dantrolene Treatment on Ventricular Electrophysiology and Arrhythmogenesis in Rats With Chronic β-Adrenergic Receptor Activation', 'display_name': 'Effects of Dantrolene Treatment on Ventricular Electrophysiology and Arrhythmogenesis in Rats With Chronic β-Adrenergic Receptor Activation', 'publication_year': 2015, 'publication_date': '2015-01-21', 'ids': {'openalex': 'https://openalex.org/W2125209491', 'doi': 'https://doi.org/10.1177/1074248414568194', 'mag': '2125209491', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25613464'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1177/1074248414568194', 'pdf_url': 'https://journals.sagepub.com/doi/pdf/10.1177/1074248414568194', 'source': {'id': 'https://openalex.org/S130832228', 'display_name': 'Journal of Cardiovascular Pharmacology and Therapeutics', 'issn_l': '1074-2484', 'issn': 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'performed': [73], 'assess': [75], 'action': [76, 83], 'potential': [77, 84], 'duration': [78, 85], 'restitution': [79], '(APDR)': [80], 'induce': [82], '(APD)': [86], 'alternans': [87, 274], 'VA': [89, 276, 311], 'vitro.': [91], 'The': [92, 209], 'protein': [93, 166, 176, 194, 199], 'levels': [94, 167, 195, 200, 218, 254], 'Cav1.2,': [96], 'sarcoplasmic': [97, 302], 'reticulum': [98, 303], 'Ca': [99, 211], '2+': [100, 212, 214, 251], '-ATPase': [101], '(SERCA2a),': [102], 'ryanodine': [104], '(RyR2)': [107], 'detected': [109], 'by': [110, 152, 220, 256, 279], 'Western': [111], 'blot.': [112], 'Compared': [113], 'control': [116, 237], 'group,': [117, 187], 'administration': [119, 162, 258], 'significantly': [122, 163, 228], 'increased': [123, 173, 229], 'APD,': [124], 'maximum': [126], 'slope': [127], '(S': [128], 'max': [129, 140], ')': [130, 217], 'APDR': [132], 'curve,': [133], 'spatial': [136], 'dispersions': [137], 'S': [139], 'APD': [142, 273], '(all': [143, 155, 178, 205, 283], 'P': [144, 156, 179, 206, 240, 262, 284], '<': [145, 157, 180, 207, 241, 263, 285], '.01),': [146], 'all': [148], 'attenuated': [151], '.05).': [158, 181, 208, 264, 286], 'Additionally,': [159], 'reduced': [164, 246], 'SERCA2': [169], 'RyR2,': [171], 'but': [172], 'Cav1.2': [175, 198], 'expression': [177, 299], 'However,': [182], 'compared': [183, 234], 'preserved': [190], 'SERCA2a': [191], 'RyR2': [193], 'decreased': [197], 'ID': [203], 'group': [204, 233, 238], 'intracellular': [210], '([Ca': [213], ']': [215, 252], 'i': [216, 253], 'measured': [219], 'incubating': [221], 'isolated': [222], 'cardiomyocytes': [223], 'Fluo-3/alveolar': [225], 'macrophages': [226], '(': [239, 261], '.01).': [242], 'Dantrolene': [243, 265], 'markedly': [245], 'rise': [248], '[Ca': [250], 'caused': [255], 'also': [267], 'prevented': [268], 'reductions': [270], 'thresholds': [277], 'induced': [278], 'stimulation': [282], 'These': [287], 'data': [288], 'suggest': [289], 'that': [290], 'stabilizes': [292], 'characteristics': [295], 'increases': [297], 'key': [301], 'calcium': [304], 'cycling': [305], 'proteins': [306], 'reduce': [308], 'vulnerability': [309], 'β-AR': [316], 'activation.': [317]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2125209491', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2025-01-08T09:17:59.698826', 'created_date': '2016-06-24'}