Title: The Use of Radical Cyclization in the Preparation of Substituted Methyl Carbapenem Antibiotic Precursors
Abstract: Angewandte Chemie International Edition in EnglishVolume 32, Issue 6 p. 867-869 Communication The Use of Radical Cyclization in the Preparation of Substituted Methyl Carbapenem Antibiotic Precursors† Dr. Josefa Anaya, Corresponding Author Dr. Josefa Anaya Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorProf. Dr. Derek H. R. Barton, Prof. Dr. Derek H. R. Barton Department of Chemistry, Texas A & M University, Texas (USA)Search for more papers by this authorDr. Stephan D. Gero, Dr. Stephan D. Gero Institut de Chimie des Substances Naturelles, C.N.R.S., Gif sur Yvette (France)Search for more papers by this authorProf. Dr. Manual Grande, Prof. Dr. Manual Grande Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorNieves Martín, Nieves Martín Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorDr. Catherine Tachdijian, Dr. Catherine Tachdijian Department of Chemistry, Texas A & M University, Texas (USA)Search for more papers by this author Dr. Josefa Anaya, Corresponding Author Dr. Josefa Anaya Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorProf. Dr. Derek H. R. Barton, Prof. Dr. Derek H. R. Barton Department of Chemistry, Texas A & M University, Texas (USA)Search for more papers by this authorDr. Stephan D. Gero, Dr. Stephan D. Gero Institut de Chimie des Substances Naturelles, C.N.R.S., Gif sur Yvette (France)Search for more papers by this authorProf. Dr. Manual Grande, Prof. Dr. Manual Grande Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorNieves Martín, Nieves Martín Universidad de Salamanca, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Plaza de los Caídos, 1–5, E-37008 Salamanca (Spain)Search for more papers by this authorDr. Catherine Tachdijian, Dr. Catherine Tachdijian Department of Chemistry, Texas A & M University, Texas (USA)Search for more papers by this author First published: June 1993 https://doi.org/10.1002/anie.199308671Citations: 27 † Penem is an abbreviation for the basic framework of unsaturated penicillins: 4-thia-1-azabicyclo[3.2.0]hept-2-en-7-one. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract A new route to β-lactam antibiotics is opened by the reaction sequence sketched below, which starts from monobactams. R1R2 = CMe2. References 1 J. S. Kahan, F. Kahan, R. Goegelman, S. A. Currie, M. Jackson, E. O. Stapley, A. K. Miller, D. Hendin, S. Mochales, S. Hernández, H. B. Woodruff, J. Birnbaum, J. Antibiot. 1979, 32, 1; 10.7164/antibiotics.32.1 CASPubMedWeb of Science®Google Scholar K. Yamamoto, T. Yoshioka, Y. Kato, N. Shibamoto, K. Okamura, Y. 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Publication Year: 1993
Publication Date: 1993-06-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 29
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