Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2124505391', 'doi': 'https://doi.org/10.1128/mcb.25.8.3087-3108.2005', 'title': 'Identification of Nuclear Import and Export Signals within Fli-1: Roles of the Nuclear Import Signals in Fli-1-Dependent Activation of Megakaryocyte-Specific Promoters', 'display_name': 'Identification of Nuclear Import and Export Signals within Fli-1: Roles of the Nuclear Import Signals in Fli-1-Dependent Activation of Megakaryocyte-Specific Promoters', 'publication_year': 2005, 'publication_date': '2005-03-29', 'ids': {'openalex': 'https://openalex.org/W2124505391', 'doi': 'https://doi.org/10.1128/mcb.25.8.3087-3108.2005', 'mag': '2124505391', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15798196', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1069587'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/mcb.25.8.3087-3108.2005', 'pdf_url': 'https://mcb.asm.org/content/mcb/25/8/3087.full.pdf', 'source': {'id': 'https://openalex.org/S81455967', 'display_name': 'Molecular and Cellular Biology', 'issn_l': '0270-7306', 'issn': ['0270-7306', '1067-8824', '1098-5549'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://mcb.asm.org/content/mcb/25/8/3087.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5066778068', 'display_name': 'Wei Hu', 'orcid': 'https://orcid.org/0000-0002-0392-6939'}, 'institutions': [{'id': 'https://openalex.org/I31746571', 'display_name': 'UNSW Sydney', 'ror': 'https://ror.org/03r8z3t63', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I31746571']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Wei Hu', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, Department of Medicine, SXt. George Clinical School, University of New South Wales, Sydney, New South Wales 2217, Australia.'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, Department of Medicine, SXt. George Clinical School, University of New South Wales, Sydney, New South Wales 2217, Australia.', 'institution_ids': ['https://openalex.org/I31746571']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020839577', 'display_name': 'Alana S. Philips', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I31746571', 'display_name': 'UNSW Sydney', 'ror': 'https://ror.org/03r8z3t63', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I31746571']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Alana S. Philips', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia', 'institution_ids': ['https://openalex.org/I31746571']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103578469', 'display_name': 'Juliana C. Kwok', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I31746571', 'display_name': 'UNSW Sydney', 'ror': 'https://ror.org/03r8z3t63', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I31746571']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Juliana C. Kwok', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia', 'institution_ids': ['https://openalex.org/I31746571']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029883166', 'display_name': 'Michael Eisbacher', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I31746571', 'display_name': 'UNSW Sydney', 'ror': 'https://ror.org/03r8z3t63', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I31746571']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Michael Eisbacher', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia', 'institution_ids': ['https://openalex.org/I31746571']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5081207687', 'display_name': 'Beng H. Chong', 'orcid': 'https://orcid.org/0000-0002-7561-490X'}, 'institutions': [{'id': 'https://openalex.org/I31746571', 'display_name': 'UNSW Sydney', 'ror': 'https://ror.org/03r8z3t63', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I31746571']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Beng H. Chong', 'raw_affiliation_strings': ['Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia'], 'affiliations': [{'raw_affiliation_string': 'Centre for Thrombosis and Vascular Research, Department of Medicine, St. George Clinical School, University of New South Wales, Sydney, New South Wales, Australia', 'institution_ids': ['https://openalex.org/I31746571']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.991, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.738109, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '25', 'issue': '8', 'first_page': '3087', 'last_page': '3108'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11841', 'display_name': 'Nuclear Structure and Function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11841', 'display_name': 'Nuclear Structure and Function', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/nls', 'display_name': 'NLS', 'score': 0.7667461}, {'id': 'https://openalex.org/keywords/nuclear-export-signal', 'display_name': 'Nuclear export signal', 'score': 0.74340796}, {'id': 'https://openalex.org/keywords/importin', 'display_name': 'Importin', 'score': 0.71617055}], 'concepts': [{'id': 'https://openalex.org/C59157529', 'wikidata': 'https://www.wikidata.org/wiki/Q994741', 'display_name': 'Nuclear transport', 'level': 4, 'score': 0.8502916}, {'id': 'https://openalex.org/C49805395', 'wikidata': 'https://www.wikidata.org/wiki/Q910966', 'display_name': 'Nuclear localization sequence', 'level': 3, 'score': 0.8472601}, {'id': 'https://openalex.org/C186435350', 'wikidata': 'https://www.wikidata.org/wiki/Q1050365', 'display_name': 'NLS', 'level': 4, 'score': 0.7667461}, {'id': 'https://openalex.org/C54757728', 'wikidata': 'https://www.wikidata.org/wiki/Q3511067', 'display_name': 'Nuclear export signal', 'level': 4, 'score': 0.74340796}, {'id': 'https://openalex.org/C133882971', 'wikidata': 'https://www.wikidata.org/wiki/Q24205524', 'display_name': 'Importin', 'level': 5, 'score': 0.71617055}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.65890527}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.50932705}, {'id': 'https://openalex.org/C29512474', 'wikidata': 'https://www.wikidata.org/wiki/Q16860021', 'display_name': 'Nuclear protein', 'level': 4, 'score': 0.4672653}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.4255283}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4152749}, {'id': 'https://openalex.org/C2780114586', 'wikidata': 'https://www.wikidata.org/wiki/Q40260', 'display_name': 'Cell nucleus', 'level': 3, 'score': 0.37172532}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.29106018}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.25043595}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.19989261}], 'mesh': [{'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D008533', 'descriptor_name': 'Megakaryocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D015533', 'descriptor_name': 'Transcriptional Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D021581', 'descriptor_name': 'Active Transport, Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021581', 'descriptor_name': 'Active Transport, Cell Nucleus', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D021581', 'descriptor_name': 'Active Transport, Cell Nucleus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020816', 'descriptor_name': 'Amino Acid Motifs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001667', 'descriptor_name': 'Binding, Competitive', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004252', 'descriptor_name': 'DNA Mutational Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008533', 'descriptor_name': 'Megakaryocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019913', 'descriptor_name': 'Nuclear Localization Signals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051789', 'descriptor_name': 'Proto-Oncogene Protein c-fli-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D028901', 'descriptor_name': 'alpha Karyopherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D028901', 'descriptor_name': 'alpha Karyopherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D028961', 'descriptor_name': 'beta Karyopherins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D028961', 'descriptor_name': 'beta Karyopherins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/mcb.25.8.3087-3108.2005', 'pdf_url': 'https://mcb.asm.org/content/mcb/25/8/3087.full.pdf', 'source': {'id': 'https://openalex.org/S81455967', 'display_name': 'Molecular and Cellular Biology', 'issn_l': '0270-7306', 'issn': ['0270-7306', '1067-8824', '1098-5549'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1069587', 'pdf_url': 'https://europepmc.org/articles/pmc1069587?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069587', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15798196', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/mcb.25.8.3087-3108.2005', 'pdf_url': 'https://mcb.asm.org/content/mcb/25/8/3087.full.pdf', 'source': {'id': 'https://openalex.org/S81455967', 'display_name': 'Molecular and Cellular Biology', 'issn_l': '0270-7306', 'issn': ['0270-7306', '1067-8824', '1098-5549'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.51, 'id': 'https://metadata.un.org/sdg/17', 'display_name': 'Partnerships for the goals'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1503116502', 'https://openalex.org/W1503329918', 'https://openalex.org/W1560988201', 'https://openalex.org/W1563529848', 'https://openalex.org/W1773446223', 'https://openalex.org/W1870505444', 'https://openalex.org/W1951130496', 'https://openalex.org/W1968863167', 'https://openalex.org/W1969172517', 'https://openalex.org/W1975142360', 'https://openalex.org/W1983612778', 'https://openalex.org/W1987860409', 'https://openalex.org/W1991018390', 'https://openalex.org/W1996093792', 'https://openalex.org/W1996381709', 'https://openalex.org/W1997948433', 'https://openalex.org/W1998973642', 'https://openalex.org/W2013462996', 'https://openalex.org/W2014049270', 'https://openalex.org/W2015853064', 'https://openalex.org/W2039078045', 'https://openalex.org/W2041590024', 'https://openalex.org/W2048130209', 'https://openalex.org/W2051628416', 'https://openalex.org/W2051665782', 'https://openalex.org/W2056455937', 'https://openalex.org/W2058041522', 'https://openalex.org/W2061632297', 'https://openalex.org/W2062987838', 'https://openalex.org/W2071131200', 'https://openalex.org/W2079045007', 'https://openalex.org/W2084775802', 'https://openalex.org/W2086725260', 'https://openalex.org/W2087302056', 'https://openalex.org/W2092308816', 'https://openalex.org/W2097239500', 'https://openalex.org/W2116230332', 'https://openalex.org/W2120226363', 'https://openalex.org/W2138983604', 'https://openalex.org/W2147074981', 'https://openalex.org/W2152961603', 'https://openalex.org/W2155675893', 'https://openalex.org/W2156891333', 'https://openalex.org/W2158923873', 'https://openalex.org/W2165306451', 'https://openalex.org/W4290129686', 'https://openalex.org/W66848399'], 'related_works': ['https://openalex.org/W4320913516', 'https://openalex.org/W3122888278', 'https://openalex.org/W2624027055', 'https://openalex.org/W2574320882', 'https://openalex.org/W2353903672', 'https://openalex.org/W2143569646', 'https://openalex.org/W2081580769', 'https://openalex.org/W2040475713', 'https://openalex.org/W2016587446', 'https://openalex.org/W1975718215'], 'abstract_inverted_index': {'The': [0], 'Ets': [1, 41, 128], 'factor': [2], 'Friend': [3], 'leukemia': [4], 'integration': [5], '1': [6], '(Fli-1)': [7], 'is': [8, 29, 38, 188], 'an': [9], 'important': [10], 'regulator': [11], 'of': [12, 45, 52, 64, 198], 'megakaryocytic': [13], '(Mk)': [14], 'differentiation.': [15], 'Here,': [16], 'we': [17, 175], 'demonstrate': [18, 126], 'two': [19, 54, 178], 'novel': [20], 'nuclear': [21, 62, 74, 113], 'localization': [22], 'signals': [23], '(NLSs)': [24], 'within': [25, 39, 70], 'Fli-1:': [26], 'one': [27, 112], '(NLS1)': [28], 'located': [30], 'at': [31], 'the': [32, 40, 48, 53, 71, 82, 141, 161, 194], 'N': [33], 'terminus,': [34], 'and': [35, 95, 99, 106, 154, 171, 184], 'another': [36], '(NLS2)': [37], 'domain.': [42], 'Nuclear': [43], 'accumulation': [44], 'Fli-1': [46, 109, 150, 167, 183, 192], 'reflected': [47], 'combined': [49, 172], 'functional': [50, 179], 'effects': [51], 'discrete': [55], 'NLSs.': [56], 'Each': [57], 'NLS': [58, 187], 'can': [59], 'independently': [60], 'direct': [61], 'transport': [63], 'a': [65, 78, 86, 146], 'carrier': [66], 'protein,': [67], 'with': [68, 97], 'mutations': [69], 'NLSs': [72, 90, 180], 'affecting': [73], 'accumulation.': [75], 'NLS1': [76, 98], 'has': [77], 'bipartite': [79], 'motif,': [80], 'whereas': [81], 'NLS2': [83, 100], 'region': [84], 'contains': [85, 111], 'nonclassical': [87], 'NLS.': [88], 'Both': [89], 'bind': [91], 'importin': [92], 'alpha': [93], '(IMPalpha)': [94], 'IMPbeta,': [96, 107], 'being': [101], 'predominantly': [102], 'recognized': [103], 'by': [104, 164], 'IMPalpha': [105], 'respectively.': [108], 'also': [110], 'export': [114], 'signal.': [115], 'Leptomycin': [116], 'B': [117], 'abolished': [118], 'its': [119, 152], 'cytoplasmic': [120], 'accumulation,': [121], 'showing': [122], 'CRM1': [123], 'dependency.': [124], 'We': [125], 'that': [127, 140, 177, 185], 'domain': [129], 'binding': [130, 144], 'to': [131, 151, 160, 190, 193], 'specific': [132], 'target': [133, 191], 'DNA': [134, 143], 'effectively': [135], 'blocks': [136], 'IMP': [137], 'binding,': [138], 'indicating': [139], 'targeted': [142], 'plays': [145], 'role': [147], 'in': [148, 182], 'localizing': [149], 'destination': [153], 'releasing': [155], 'IMPs': [156], 'for': [157, 196], 'recycling': [158], 'back': [159], 'cytoplasm.': [162], 'Finally,': [163], 'analyzing': [165], 'full-length': [166], 'carrying': [168], 'NLS1,': [169], 'NLS2,': [170], 'NLS1-NLS2': [173], 'mutations,': [174], 'conclude': [176], 'exist': [181], 'each': [186], 'sufficient': [189], 'nucleus': [195], 'activation': [197], 'Mk-specific': [199], 'genes.': [200]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2124505391', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-08T18:06:44.964586', 'created_date': '2016-06-24'}