<i>Saccharomyces cerevisiae</i> Ccr4–Not complex contributes to the control of Msn2p‐dependent transcription by the Ras/cAMP pathway

Name: Work Video:
Duration: 3 min 30 s
Eve Lenssen; Ursula Oberholzer; Jean Labarre; Claudio De Virgilio; Martine A. Collart
{'id': 'https://openalex.org/W2124378587', 'doi': 'https://doi.org/10.1046/j.1365-2958.2002.02799.x', 'title': '<i>Saccharomyces cerevisiae</i> Ccr4–Not complex contributes to the control of Msn2p‐dependent transcription by the Ras/cAMP pathway', 'display_name': '<i>Saccharomyces cerevisiae</i> Ccr4–Not complex contributes to the control of Msn2p‐dependent transcription by the Ras/cAMP pathway', 'publication_year': 2002, 'publication_date': '2002-02-01', 'ids': {'openalex': 'https://openalex.org/W2124378587', 'doi': 'https://doi.org/10.1046/j.1365-2958.2002.02799.x', 'mag': '2124378587', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11929548'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1365-2958.2002.02799.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S102549058', 'display_name': 'Molecular Microbiology', 'issn_l': '0950-382X', 'issn': ['0950-382X', '1365-2958'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050530510', 'display_name': 'Eve Lenssen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210144193', 'display_name': 'Biotechnology Research Institute', 'ror': 'https://ror.org/04eba5983', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210144193', 'https://openalex.org/I4210159778']}, {'id': 'https://openalex.org/I74973139', 'display_name': 'Carnegie Mellon University', 'ror': 'https://ror.org/05x2bcf33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I74973139']}], 'countries': ['CA', 'US'], 'is_corresponding': False, 'raw_author_name': 'E. Lenssen', 'raw_affiliation_strings': ['Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', '†Present address: Biotechnology Research Institute, Montreal, Canada.'], 'affiliations': [{'raw_affiliation_string': '†Present address: Biotechnology Research Institute, Montreal, Canada.', 'institution_ids': ['https://openalex.org/I4210144193']}, {'raw_affiliation_string': 'Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', 'institution_ids': ['https://openalex.org/I74973139']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048265331', 'display_name': 'Ursula Oberholzer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I74973139', 'display_name': 'Carnegie Mellon University', 'ror': 'https://ror.org/05x2bcf33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I74973139']}, {'id': 'https://openalex.org/I4210144193', 'display_name': 'Biotechnology Research Institute', 'ror': 'https://ror.org/04eba5983', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210144193', 'https://openalex.org/I4210159778']}, {'id': 'https://openalex.org/I4210119046', 'display_name': 'Zero to Three', 'ror': 'https://ror.org/01qvk6016', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210119046']}], 'countries': ['CA', 'US'], 'is_corresponding': False, 'raw_author_name': 'U. Oberholzer', 'raw_affiliation_strings': ['Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', '†Present address: Biotechnology Research Institute, Montreal, Canada.', '‡The first two authors contributed equally to this work.'], 'affiliations': [{'raw_affiliation_string': 'Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', 'institution_ids': ['https://openalex.org/I74973139']}, {'raw_affiliation_string': '†Present address: Biotechnology Research Institute, Montreal, Canada.', 'institution_ids': ['https://openalex.org/I4210144193']}, {'raw_affiliation_string': '‡The first two authors contributed equally to this work.', 'institution_ids': ['https://openalex.org/I4210119046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023151142', 'display_name': 'Jean Labarre', 'orcid': 'https://orcid.org/0000-0002-1489-0046'}, 'institutions': [{'id': 'https://openalex.org/I2801360556', 'display_name': 'CEA Paris-Saclay - Etablissement de Saclay', 'ror': 'https://ror.org/01fv25t22', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I142476485', 'https://openalex.org/I2738703131', 'https://openalex.org/I2801360556', 'https://openalex.org/I4210128565', 'https://openalex.org/I4210145102', 'https://openalex.org/I83860666', 'https://openalex.org/I84909340']}, {'id': 'https://openalex.org/I4210128565', 'display_name': 'CEA Paris-Saclay', 'ror': 'https://ror.org/03n15ch10', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210128565']}, {'id': 'https://openalex.org/I2738703131', 'display_name': "Commissariat à l'Énergie Atomique et aux Énergies Alternatives", 'ror': 'https://ror.org/00jjx8s55', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I2738703131']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J. Labarre', 'raw_affiliation_strings': ['CEA Saclay, France.'], 'affiliations': [{'raw_affiliation_string': 'CEA Saclay, France.', 'institution_ids': ['https://openalex.org/I2801360556', 'https://openalex.org/I4210128565', 'https://openalex.org/I2738703131']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037927525', 'display_name': 'Claudio De Virgilio', 'orcid': 'https://orcid.org/0000-0001-8826-4323'}, 'institutions': [{'id': 'https://openalex.org/I74973139', 'display_name': 'Carnegie Mellon University', 'ror': 'https://ror.org/05x2bcf33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I74973139']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C. De Virgilio', 'raw_affiliation_strings': ['Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', 'institution_ids': ['https://openalex.org/I74973139']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006946686', 'display_name': 'Martine A. Collart', 'orcid': 'https://orcid.org/0000-0001-6955-1773'}, 'institutions': [{'id': 'https://openalex.org/I74973139', 'display_name': 'Carnegie Mellon University', 'ror': 'https://ror.org/05x2bcf33', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I74973139']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'M. A. Collart', 'raw_affiliation_strings': ['Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.'], 'affiliations': [{'raw_affiliation_string': 'Department Biochimie Médicale, CMU, 1 rue Michel Servet, 1211 Genève 4, Switzerland.', 'institution_ids': ['https://openalex.org/I74973139']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5006946686'], 'corresponding_institution_ids': ['https://openalex.org/I74973139'], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.824, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 74, 'citation_normalized_percentile': {'value': 0.939351, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '43', 'issue': '4', 'first_page': '1023', 'last_page': '1037'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10497', 'display_name': 'Fungal and yeast genetics research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10497', 'display_name': 'Fungal and yeast genetics research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription', 'score': 0.5891749}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.845873}, {'id': 'https://openalex.org/C51785407', 'wikidata': 'https://www.wikidata.org/wiki/Q2627568', 'display_name': 'Effector', 'level': 2, 'score': 0.6853675}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.63151574}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.5891749}, {'id': 'https://openalex.org/C2777576037', 'wikidata': 'https://www.wikidata.org/wiki/Q719725', 'display_name': 'Saccharomyces cerevisiae', 'level': 3, 'score': 0.58787495}, {'id': 'https://openalex.org/C172768829', 'wikidata': 'https://www.wikidata.org/wiki/Q14817959', 'display_name': 'Transcription factor II D', 'level': 5, 'score': 0.5071268}, {'id': 'https://openalex.org/C143065580', 'wikidata': 'https://www.wikidata.org/wiki/Q3285695', 'display_name': 'Mutant', 'level': 3, 'score': 0.50001526}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.48914936}, {'id': 'https://openalex.org/C6929976', 'wikidata': 'https://www.wikidata.org/wiki/Q3771881', 'display_name': 'Regulator', 'level': 3, 'score': 0.4741335}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.46320856}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4574451}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.24885476}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.22930592}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005656', 'descriptor_name': 'Fungal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015966', 'descriptor_name': 'Gene Expression Regulation, Fungal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012260', 'descriptor_name': 'Ribonucleases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018631', 'descriptor_name': 'ras Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003470', 'descriptor_name': 'Culture Media', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017868', 'descriptor_name': 'Cyclic AMP-Dependent Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005656', 'descriptor_name': 'Fungal Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005656', 'descriptor_name': 'Fungal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005947', 'descriptor_name': 'Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018840', 'descriptor_name': 'HSP70 Heat-Shock Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D018840', 'descriptor_name': 'HSP70 Heat-Shock Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016296', 'descriptor_name': 'Mutagenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011499', 'descriptor_name': 'Protein Processing, Post-Translational', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012260', 'descriptor_name': 'Ribonucleases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012260', 'descriptor_name': 'Ribonucleases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018631', 'descriptor_name': 'ras Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1365-2958.2002.02799.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S102549058', 'display_name': 'Molecular Microbiology', 'issn_l': '0950-382X', 'issn': ['0950-382X', '1365-2958'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11929548', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 55, 'referenced_works': ['https://openalex.org/W1491758006', 'https://openalex.org/W1519192656', 'https://openalex.org/W1539988911', 'https://openalex.org/W1591531412', 'https://openalex.org/W1614347411', 'https://openalex.org/W1716734578', 'https://openalex.org/W1813812686', 'https://openalex.org/W1912625738', 'https://openalex.org/W1964866269', 'https://openalex.org/W1977664347', 'https://openalex.org/W1998326358', 'https://openalex.org/W1999657661', 'https://openalex.org/W2003512520', 'https://openalex.org/W2004368359', 'https://openalex.org/W2023933641', 'https://openalex.org/W2026059959', 'https://openalex.org/W2037334851', 'https://openalex.org/W2037992536', 'https://openalex.org/W2046385725', 'https://openalex.org/W2047148652', 'https://openalex.org/W2059085198', 'https://openalex.org/W2072278791', 'https://openalex.org/W2075717456', 'https://openalex.org/W2097294952', 'https://openalex.org/W2100617260', 'https://openalex.org/W2100898573', 'https://openalex.org/W2101432256', 'https://openalex.org/W2101882623', 'https://openalex.org/W2109500897', 'https://openalex.org/W2110829136', 'https://openalex.org/W2115238017', 'https://openalex.org/W2117403504', 'https://openalex.org/W2119928648', 'https://openalex.org/W2127321901', 'https://openalex.org/W2127754721', 'https://openalex.org/W2128098474', 'https://openalex.org/W2132444456', 'https://openalex.org/W2135776390', 'https://openalex.org/W2136595023', 'https://openalex.org/W2137683543', 'https://openalex.org/W2139118115', 'https://openalex.org/W2140754979', 'https://openalex.org/W2147989314', 'https://openalex.org/W2150904401', 'https://openalex.org/W2152997106', 'https://openalex.org/W2154124725', 'https://openalex.org/W2156776764', 'https://openalex.org/W2165130891', 'https://openalex.org/W2165238717', 'https://openalex.org/W2167348821', 'https://openalex.org/W2169832274', 'https://openalex.org/W2170778160', 'https://openalex.org/W4237712833', 'https://openalex.org/W4238523586', 'https://openalex.org/W4239029175'], 'related_works': ['https://openalex.org/W4380992933', 'https://openalex.org/W4320492283', 'https://openalex.org/W4309090929', 'https://openalex.org/W4214695225', 'https://openalex.org/W3197607994', 'https://openalex.org/W3020059968', 'https://openalex.org/W2783284266', 'https://openalex.org/W2354064740', 'https://openalex.org/W2171209136', 'https://openalex.org/W1530034981'], 'abstract_inverted_index': {'Summary': [0], 'The': [1], 'Ccr4–Not': [2, 34, 164], 'complex': [3, 35, 165], 'is': [4, 17, 54, 66, 74], 'a': [5, 98, 122, 152], 'global': [6], 'regulator': [7], 'of': [8, 23, 61, 81, 120, 129, 171], 'transcription': [9, 183], 'that': [10, 32, 107, 144, 162, 175], 'affects': [11], 'genes': [12, 95], 'positively': [13], 'and': [14, 16, 113, 127, 133, 138, 181], 'negatively': [15], 'thought': [18], 'to': [19, 38, 56, 87, 147, 177], 'modulate': [20], 'the': [21, 26, 33, 42, 118, 163, 172], 'activity': [22, 112], 'TFIID.': [24], 'In': [25], 'present': [27], 'work,': [28], 'we': [29], 'provide': [30], 'evidence': [31], 'may': [36, 166], 'contribute': [37], 'transcriptional': [39], 'regulation': [40], 'by': [41, 76, 141, 184], 'Ras/cAMP': [43, 173], 'pathway.': [44], 'Several': [45], 'observations': [46], 'support': [47], 'this': [48], 'model.': [49], 'First,': [50], 'Msn2/4p‐dependent': [51, 149], 'transcription,': [52], 'which': [53, 135], 'known': [55], 'be': [57], 'under': [58], 'negative': [59], 'control': [60], 'cAMP‐dependent': [62], 'protein': [63], 'kinase': [64], '(PKA),': [65], 'derepressed': [67], 'in': [68, 83, 92, 97], 'all': [69], 'ccr4–not': [70, 84], 'mutants.': [71], 'This': [72], 'phenotype': [73], 'paralleled': [75], 'specific': [77, 153], 'post‐translational': [78], 'modification': [79], 'defects': [80], 'Msn2p': [82], 'mutants': [85], 'relative': [86], 'wild‐type': [88], 'cells.': [89], 'Secondly,': [90], 'mutations': [91, 106], 'various': [93], 'NOT': [94], 'result': [96], 'synthetic': [99], 'temperature‐sensitive': [100], 'growth': [101], 'defect': [102], 'when': [103], 'combined': [104], 'with': [105, 156], 'compromise': [108], 'cells': [109], 'for': [110], 'PKA': [111], 'at': [114], 'least': [115], 'partially': [116], 'suppress': [117], 'effects': [119], 'both': [121], 'dominant‐active': [123], 'RAS2': [124], 'Val‐19': [125], 'allele': [126], 'loss': [128], 'Rim15p.': [130], 'Thirdly,': [131], 'Not3p': [132], 'Not5p,': [134], 'are': [136], 'modified': [137], 'subsequently': [139], 'degraded': [140], 'stress': [142], 'signals': [143], 'also': [145], 'lead': [146], 'increased': [148], 'activity,': [150], 'show': [151], 'two‐hybrid': [154], 'interaction': [155], 'Tpk2p.': [157], 'Together,': [158], 'our': [159], 'results': [160], 'suggest': [161], 'function': [167], 'as': [168], 'an': [169], 'effector': [170], 'pathway': [174], 'contributes': [176], 'repress': [178], 'basal,': [179], 'stress‐': [180], 'starvation‐induced': [182], 'Msn2/4p.': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2124378587', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-17T07:07:18.874218', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
