Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2123914496', 'doi': 'https://doi.org/10.1681/asn.2012070734', 'title': 'The Treatment of Minimal Change Disease in Adults', 'display_name': 'The Treatment of Minimal Change Disease in Adults', 'publication_year': 2013, 'publication_date': '2013-02-22', 'ids': {'openalex': 'https://openalex.org/W2123914496', 'doi': 'https://doi.org/10.1681/asn.2012070734', 'mag': '2123914496', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23431071'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1681/asn.2012070734', 'pdf_url': 'https://jasn.asnjournals.org/content/jnephrol/24/5/702.full.pdf', 'source': {'id': 'https://openalex.org/S115693375', 'display_name': 'Journal of the American Society of Nephrology', 'issn_l': '1046-6673', 'issn': ['1046-6673', '1533-3450'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315620', 'host_organization_name': 'American Society of Nephrology', 'host_organization_lineage': ['https://openalex.org/P4310315620'], 'host_organization_lineage_names': ['American Society of Nephrology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://jasn.asnjournals.org/content/jnephrol/24/5/702.full.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109705744', 'display_name': 'Jonathan Hogan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799503643', 'display_name': 'Columbia University Irving Medical Center', 'ror': 'https://ror.org/01esghr10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799503643']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan Hogan', 'raw_affiliation_strings': ['Division of Nephrology, Columbia University Medical Center, New York, New York'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology, Columbia University Medical Center, New York, New York', 'institution_ids': ['https://openalex.org/I2799503643']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5088037254', 'display_name': 'Jai Radhakrishnan', 'orcid': 'https://orcid.org/0000-0003-3157-5141'}, 'institutions': [{'id': 'https://openalex.org/I2799503643', 'display_name': 'Columbia University Irving Medical Center', 'ror': 'https://ror.org/01esghr10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799503643']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Jai Radhakrishnan', 'raw_affiliation_strings': ['Division of Nephrology, Columbia University Medical Center, New York, New York', 'Dr. Jai Radhakrishnan, Columbia University Medical Center—Internal Medicine, Division of Nephrology, 622 West 168th Street, PH 4-124, New York, NY 10025. Email: [email\xa0protected]'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology, Columbia University Medical Center, New York, New York', 'institution_ids': ['https://openalex.org/I2799503643']}, {'raw_affiliation_string': 'Dr. Jai Radhakrishnan, Columbia University Medical Center—Internal Medicine, Division of Nephrology, 622 West 168th Street, PH 4-124, New York, NY 10025. Email: [email\xa0protected]', 'institution_ids': ['https://openalex.org/I2799503643']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5088037254'], 'corresponding_institution_ids': ['https://openalex.org/I2799503643'], 'apc_list': None, 'apc_paid': None, 'fwci': 1.732, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 148, 'citation_normalized_percentile': {'value': 0.997967, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '24', 'issue': '5', 'first_page': '702', 'last_page': '711'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11029', 'display_name': 'Renal Diseases and Glomerulopathies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11029', 'display_name': 'Renal Diseases and Glomerulopathies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus Research', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11157', 'display_name': 'Chronic Lymphocytic Leukemia Research', 'score': 0.9844, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/minimal-change-disease', 'display_name': 'Minimal change disease', 'score': 0.9236746}, {'id': 'https://openalex.org/keywords/etiology', 'display_name': 'Etiology', 'score': 0.69356394}], 'concepts': [{'id': 'https://openalex.org/C2777747828', 'wikidata': 'https://www.wikidata.org/wiki/Q1323002', 'display_name': 'Minimal change disease', 'level': 5, 'score': 0.9236746}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7700856}, {'id': 'https://openalex.org/C23131810', 'wikidata': 'https://www.wikidata.org/wiki/Q818574', 'display_name': 'Observational study', 'level': 2, 'score': 0.7380727}, {'id': 'https://openalex.org/C137627325', 'wikidata': 'https://www.wikidata.org/wiki/Q156318', 'display_name': 'Etiology', 'level': 2, 'score': 0.69356394}, {'id': 'https://openalex.org/C2778930706', 'wikidata': 'https://www.wikidata.org/wiki/Q504790', 'display_name': 'Nephrotic syndrome', 'level': 2, 'score': 0.62192374}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.5151435}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.50291294}, {'id': 'https://openalex.org/C205545832', 'wikidata': 'https://www.wikidata.org/wiki/Q17156455', 'display_name': 'Young adult', 'level': 2, 'score': 0.4901834}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.47671098}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.43744704}, {'id': 'https://openalex.org/C2780368995', 'wikidata': 'https://www.wikidata.org/wiki/Q605006', 'display_name': 'Glomerulonephritis', 'level': 3, 'score': 0.13793397}, {'id': 'https://openalex.org/C2778415529', 'wikidata': 'https://www.wikidata.org/wiki/Q1435223', 'display_name': 'Focal segmental glomerulosclerosis', 'level': 4, 'score': 0.07841247}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.061885387}], 'mesh': [{'descriptor_ui': 'D009402', 'descriptor_name': 'Nephrosis, Lipoid', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000305', 'descriptor_name': 'Adrenal Cortex Hormones', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000477', 'descriptor_name': 'Alkylating Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000477', 'descriptor_name': 'Alkylating Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D065095', 'descriptor_name': 'Calcineurin Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018849', 'descriptor_name': 'Controlled Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007166', 'descriptor_name': 'Immunosuppressive Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D009402', 'descriptor_name': 'Nephrosis, Lipoid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009402', 'descriptor_name': 'Nephrosis, Lipoid', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D012008', 'descriptor_name': 'Recurrence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1681/asn.2012070734', 'pdf_url': 'https://jasn.asnjournals.org/content/jnephrol/24/5/702.full.pdf', 'source': {'id': 'https://openalex.org/S115693375', 'display_name': 'Journal of the American Society of Nephrology', 'issn_l': '1046-6673', 'issn': ['1046-6673', '1533-3450'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315620', 'host_organization_name': 'American Society of Nephrology', 'host_organization_lineage': ['https://openalex.org/P4310315620'], 'host_organization_lineage_names': ['American Society of Nephrology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23431071', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1681/asn.2012070734', 'pdf_url': 'https://jasn.asnjournals.org/content/jnephrol/24/5/702.full.pdf', 'source': {'id': 'https://openalex.org/S115693375', 'display_name': 'Journal of the American Society of Nephrology', 'issn_l': '1046-6673', 'issn': ['1046-6673', '1533-3450'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315620', 'host_organization_name': 'American Society of Nephrology', 'host_organization_lineage': ['https://openalex.org/P4310315620'], 'host_organization_lineage_names': ['American Society of Nephrology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.81, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 96, 'referenced_works': ['https://openalex.org/W143991300', 'https://openalex.org/W1491720051', 'https://openalex.org/W178584113', 'https://openalex.org/W1853153242', 'https://openalex.org/W1964432644', 'https://openalex.org/W1968244520', 'https://openalex.org/W1981804630', 'https://openalex.org/W1988659027', 'https://openalex.org/W1988812807', 'https://openalex.org/W1989119018', 'https://openalex.org/W1991727937', 'https://openalex.org/W1996339513', 'https://openalex.org/W2002886229', 'https://openalex.org/W2005857868', 'https://openalex.org/W2011665041', 'https://openalex.org/W2014437621', 'https://openalex.org/W2017210187', 'https://openalex.org/W2018820337', 'https://openalex.org/W2021510282', 'https://openalex.org/W2022859904', 'https://openalex.org/W2023906012', 'https://openalex.org/W2027272349', 'https://openalex.org/W2030924703', 'https://openalex.org/W2033492666', 'https://openalex.org/W2034812514', 'https://openalex.org/W2040001010', 'https://openalex.org/W2040060591', 'https://openalex.org/W2047350914', 'https://openalex.org/W2047572954', 'https://openalex.org/W2047876945', 'https://openalex.org/W2048100349', 'https://openalex.org/W2050212057', 'https://openalex.org/W2051978504', 'https://openalex.org/W2052862354', 'https://openalex.org/W2055580456', 'https://openalex.org/W2056914489', 'https://openalex.org/W2057619478', 'https://openalex.org/W2060727722', 'https://openalex.org/W2066630582', 'https://openalex.org/W2067107031', 'https://openalex.org/W2067778425', 'https://openalex.org/W2068745620', 'https://openalex.org/W2070436637', 'https://openalex.org/W2071057112', 'https://openalex.org/W2083567492', 'https://openalex.org/W2085464825', 'https://openalex.org/W2088812049', 'https://openalex.org/W2090231740', 'https://openalex.org/W2091679838', 'https://openalex.org/W2092061005', 'https://openalex.org/W2092953388', 'https://openalex.org/W2095907955', 'https://openalex.org/W2096467430', 'https://openalex.org/W2097607531', 'https://openalex.org/W2107443834', 'https://openalex.org/W2107668112', 'https://openalex.org/W2110027487', 'https://openalex.org/W2110088490', 'https://openalex.org/W2119420462', 'https://openalex.org/W2119789850', 'https://openalex.org/W2120682062', 'https://openalex.org/W2124943795', 'https://openalex.org/W2127637322', 'https://openalex.org/W2130719877', 'https://openalex.org/W2132804616', 'https://openalex.org/W2132946747', 'https://openalex.org/W2133272865', 'https://openalex.org/W2134967104', 'https://openalex.org/W2151098851', 'https://openalex.org/W2151718023', 'https://openalex.org/W2153083931', 'https://openalex.org/W2158797289', 'https://openalex.org/W2158879557', 'https://openalex.org/W2158909939', 'https://openalex.org/W2159526233', 'https://openalex.org/W2160430974', 'https://openalex.org/W2163938727', 'https://openalex.org/W2249976830', 'https://openalex.org/W2324763410', 'https://openalex.org/W2336805596', 'https://openalex.org/W2336958257', 'https://openalex.org/W2395097224', 'https://openalex.org/W2396630481', 'https://openalex.org/W2415928046', 'https://openalex.org/W2416683641', 'https://openalex.org/W2433721867', 'https://openalex.org/W2460201178', 'https://openalex.org/W2460401876', 'https://openalex.org/W2494826048', 'https://openalex.org/W2522053674', 'https://openalex.org/W255145954', 'https://openalex.org/W3094568071', 'https://openalex.org/W4235236328', 'https://openalex.org/W4246499132', 'https://openalex.org/W4285719527', 'https://openalex.org/W4360754741'], 'related_works': ['https://openalex.org/W4256015928', 'https://openalex.org/W4248280873', 'https://openalex.org/W2610176294', 'https://openalex.org/W2426284493', 'https://openalex.org/W2409273151', 'https://openalex.org/W2069243082', 'https://openalex.org/W2066233984', 'https://openalex.org/W2018227523', 'https://openalex.org/W1973353881', 'https://openalex.org/W1936597217'], 'abstract_inverted_index': {'Minimal': [0], 'change': [1], 'disease': [2], '(MCD)': [3], 'is': [4, 25], 'the': [5, 67, 84], 'etiology': [6], 'of': [7, 9, 11, 18, 47, 69], '10%–25%': [8], 'cases': [10], 'nephrotic': [12], 'syndrome': [13], 'in': [14, 36, 44, 78, 89], 'adults.': [15], 'The': [16, 64], 'mainstay': [17], 'treatment': [19, 40, 68], 'for': [20, 86], 'adult': [21], 'MCD,': [22], 'oral': [23], 'gucocorticoids,': [24], 'based': [26], 'on': [27, 83], 'two': [28], 'randomized': [29], 'controlled': [30], 'trials': [31], 'and': [32, 38, 52], 'extensive': [33], 'observational': [34], 'data': [35, 65], 'adults,': [37], 'this': [39], 'leads': [41], 'to': [42], 'remission': [43], 'over': [45], '80%': [46], 'cases.': [48], 'Relapses': [49], 'are': [50, 72], 'common,': [51], 'some': [53], 'patients': [54, 71], 'become': [55], 'steroid-resistant': [56], '(SR),': [57], 'steroid-dependent': [58], '(SD),': [59], 'or': [60], 'frequently': [61], 'relapsing': [62], '(FR).': [63], 'guiding': [66], 'these': [70, 90], 'limited.': [73], 'Here,': [74], 'we': [75], 'review': [76], 'MCD': [77], 'adults': [79], 'with': [80], 'particular': [81], 'focus': [82], 'evidence': [85], 'immunosuppressive': [87], 'therapy': [88], 'patients.': [91]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2123914496', 'counts_by_year': [{'year': 2024, 'cited_by_count': 15}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 17}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 18}, {'year': 2018, 'cited_by_count': 18}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 15}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-19T11:05:05.068226', 'created_date': '2016-06-24'}