Molecular Characterization of a Cystathionine Beta-Synthase Gene, CBS1 , in Magnaporthe grisea

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Duration: 3 min 30 s
Description: ABSTRACT CBS1 from Magnaporthe grisea is a structural and functional homolog of the cystathionine β-synthase (CBS) gene from Saccharomyces cerevisiae . Our studies indicated that M . grisea can utilize homocysteine and methionine through a CBS-independent pathway. The results also revealed responses of M . grisea to homocysteine that are reminiscent of human homocystinuria.
Sze Chung Clive Lo; Lisbeth Hamer; John E. Hamer
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