Pharmacogenetics of Antihypertensive Response

Name: Work Video:
Duration: 3 min 30 s
Catherine Y. Campbell; Roger S. Blumenthal
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[666], 'reabsorption': [668], 'regulation': [672], 'shown': [676], 'previously': [677, 694], 'be': [679, 767, 788, 834], 'hydrochlorothiazide.15': [686], 'studies,': [698, 740], 'mechanism': [701], 'behind': [702], 'SNP': [704], 'unclear.This': [713], 'was': [715, 855], 'underpowered,': [716], '300': [718, 728], 'participants': [719, 729], 'group': [726], 'group.': [736], 'With': [737], 'much': [741], 'larger': [742], 'sample': [743], 'sizes': [744], 'needed': [746], 'adequate': [749], 'power.': [750], 'Measurement': [751], 'error': [752], 'because': [753], 'variability': [757], 'limits': [759], 'power;': [761], 'continuous': [762], 'readings': [765], 'could': [766], 'considered': [768], 'future': [770], 'improve': [773], 'accuracy': [775], 'measurements.In': [779], 'summary,': [780], 'offer': [805], 'hope': [806], 'personalized': [809], 'treatment,': [813], 'whereby': [814], 'used': [818], 'medication': [826], 'patient.': [830], 'Further': [831], 'will': [833], 'needed,': [835], 'replicate': [838], 'before': [846], 'applying': [847], 'practice.Sources': [852], 'FundingC.Y.C.': [854], 'supported': [856], 'National': [858], 'Heart,': [859], 'Lung,': [860], 'Blood': [862, 3559], 'Institute': [863], 'grant': [864], '2': [865], 'T32': [866], 'HL007024-36.DisclosuresNone.FootnotesThe': [867], 'opinions': [868], 'expressed': [869], 'editorial': [872], 'necessarily': [875], 'those': [876], 'editors': [879], 'American': [883, 3685, 3904], 'Heart': [884, 898, 3905], 'Association.Correspondence': [885], 'Campbell,': [889], 'Center': [893], 'Prevention': [896], 'Disease,': [899], 'Blalock': [900], '524C,': [901], '600': [902], 'N': [903], 'Wolfe': [904], 'St,': [905], 'MD': [907], '21287.': [908], 'E-mail': [909], '[email': [910], 'protected]eduReferences1.': [911], 'ST,': [913, 976, 3265, 3594], 'Bailey': [914, 977], 'KR,': [915, 978, 2667, 3397], 'Schwartz': [916, 983, 1381, 2620, 3595], 'GL,': [917, 984, 2026, 3596], 'Chapman': [918, 981, 3597], 'A,': [919, 1055, 1069, 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1418, 1778, 1846, 2389, 3525], 'Johnson': [1060, 1212, 1552, 1747, 1749, 2220, 2909], 'AD,': [1061, 1750, 2221, 2403, 3131], 'Aspelund': [1062, 1773, 2372], 'T,': [1063, 1067, 1213, 1241, 1366, 1368, 1442, 1553, 1588, 1748, 1774, 1776, 1810, 1834, 1898, 1928, 2034, 2275, 2329, 2355, 2373, 2561, 2567, 2573, 2575, 2577, 2585, 2697, 2809, 2910, 2922, 2954, 2956, 3005, 3007, 3071, 3091, 3193, 3281, 3325, 3375, 3427], 'Aulchenko': [1064, 1903, 2250, 3190], 'Y,': [1065, 1816, 1904, 2251, 2283, 2309, 2315, 2333, 2421, 2519, 2571, 3652], 'Lumley': [1066, 3006], 'Kottgen': [1068, 2442], 'Vasan': [1070, 1150, 1865, 2884], 'RS,': [1071, 1151, 1866, 2793, 2885, 3537], 'Rivadeneira': [1072, 1857, 2680], 'F,': [1073, 1173, 1237, 1322, 1434, 1650, 1804, 1858, 1948, 2265, 2477, 2681, 2765, 2960, 3231, 3247, 3740], 'Eiriksdottir': [1074, 3234], 'G,': [1075, 1113, 1271, 1303, 1420, 1438, 1464, 1484, 1486, 1488, 1574, 1616, 1618, 1622, 1656, 1746, 1788, 1794, 1874, 2000, 2036, 2074, 2267, 2317, 2331, 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3373, 3399, 3429, 3654], 'Harris': [1096, 1893, 2798, 3004], 'TB,': [1097, 1894, 2799, 3089], 'Ganesh': [1098, 1849, 2786], 'SK,': [1099, 1850, 2787], "O'Donnell": [1100, 1379, 1939, 2618], 'CJ,': [1101, 1356, 1380, 1940, 2619], 'Hofman': [1102, 1851, 2670], 'Rotter': [1104, 2868], 'JI,': [1105, 2869], 'Coresh': [1106, 2814], 'Benjamin': [1108, 1162, 3188, 3388], 'Uitterlinden': [1110, 1861, 2862, 2967], 'AG,': [1111, 1862, 2863], 'Heiss': [1112, 1720], 'Fox': [1114, 2290, 3344], 'CS,': [1115, 1476, 2357, 2665, 2669, 3345], 'Witteman': [1116, 2153, 2876], 'JC,': [1117, 1245, 1772, 1830, 2054, 2154, 2289, 2415, 2425, 2877], 'E,': [1119, 1181, 1291, 1370, 1600, 1918, 2161, 2343, 2507, 2739, 2757, 2883, 3077, 3189, 3239, 3369, 3446, 3465, 3543, 3742], 'Wang': [1120, 1188, 1867, 2512, 2522, 3198, 3328, 3655, 3659], 'TJ,': [1121, 1868, 2513], 'Gudnason': [1122, 2172, 2866], 'V,': [1123, 1183, 1215, 1324, 1466, 1520, 1766, 1820, 1848, 1942, 2040, 2173, 2233, 2351, 2447, 2479, 2549, 2819, 2867, 2964, 2979, 3453], 'Larson': [1124, 1148, 1763, 2888], 'MG,': [1125, 1149, 1764, 2807, 2889, 3333], 'Chakravarti': [1126, 2168, 2896, 3544], 'Psaty': [1128, 2180, 2892], 'BM,': [1129, 2181, 2893], 'van': [1130, 1250, 1404, 1477, 1577, 2013, 2157, 2190, 2296, 2661, 2774, 2900, 2969, 3437], 'Duijn': [1131, 2191, 2901, 2970], 'CM.': [1132, 2192], 'Genome-wide': [1133, 1533, 1697, 2193, 3574], 'hypertension.': [1140, 1710], 'Nat': [1141, 1205, 1543, 2207], 'Genet.': [1142, 1206, 1544, 1712, 2208, 3565], '41:677–687.CrossrefMedlineGoogle': [1144], 'Scholar7.': [1145], 'Newton-Cheh': [1146, 1210, 1645, 2174, 2903], 'C,': [1147, 1159, 1211, 1243, 1326, 1364, 1564, 1568, 1596, 1646, 1930, 1932, 2084, 2136, 2175, 2287, 2439, 2749, 2753, 2859, 2904, 2926, 2940, 2942, 2958, 2966, 2971, 3035, 3055, 3057, 3067, 3111, 3173, 3211, 3285, 3459, 3493], 'Bloch': [1154], 'KD,': [1155, 1892, 2327, 2995], 'Surti': [1156], 'Guiducci': [1158, 3110], 'Kathiresan': [1160, 1375, 1657, 2616], 'S,': [1161, 1171, 1229, 1255, 1295, 1318, 1320, 1376, 1424, 1452, 1496, 1549, 1570, 1590, 1620, 1624, 1658, 1782, 1824, 1854, 1870, 1912, 1916, 1920, 1950, 2060, 2104, 2253, 2255, 2311, 2347, 2393, 2445, 2475, 2545, 2581, 2583, 2617, 2630, 2713, 2831, 2918, 2934, 2952, 2977, 3003, 3023, 3029, 3063, 3087, 3129, 3155, 3181, 3219, 3271, 3313, 3319, 3425, 3473, 3648, 3650], 'Struck': [1164], 'Morgenthaler': [1166], 'NG,': [1167, 1472, 3431], 'Bergmann': [1168, 1294, 1869, 2444], 'Blankenberg': [1170, 2951], 'Kee': [1172], 'Nilsson': [1174, 1248, 2602], 'P,': [1175, 1249, 1253, 1301, 1328, 1338, 1426, 1448, 1458, 1512, 1526, 1580, 1632, 1638, 1648, 1688, 1690, 1756, 1792, 1872, 1880, 1910, 1979, 1989, 2124, 2138, 2189, 2235, 2261, 2299, 2471, 2603, 2644, 2695, 2699, 2711, 2719, 2731, 2783, 2861, 2899, 2948, 3047, 3049, 3309, 3485], 'Yin': [1176], 'Peltonen': [1178, 1395, 2502], 'L,': [1179, 1221, 1309, 1396, 1498, 1934, 2110, 2146, 2247, 2465, 2503, 2839, 2962, 3121, 3141, 3143, 3279, 3303, 3357, 3461, 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