Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2121826111', 'doi': 'https://doi.org/10.1083/jcb.135.1.269', 'title': 'A developmental defect in Plasmodium falciparum male gametogenesis.', 'display_name': 'A developmental defect in Plasmodium falciparum male gametogenesis.', 'publication_year': 1996, 'publication_date': '1996-10-01', 'ids': {'openalex': 'https://openalex.org/W2121826111', 'doi': 'https://doi.org/10.1083/jcb.135.1.269', 'mag': '2121826111', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8858179', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2121010'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.135.1.269', 'pdf_url': 'http://jcb.rupress.org/content/135/1/269.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://jcb.rupress.org/content/135/1/269.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5001839656', 'display_name': 'Françoise Guinet', 'orcid': 'https://orcid.org/0000-0001-5032-8117'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'F Guinet', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068229583', 'display_name': 'James A. Dvorak', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J A Dvorak', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062473075', 'display_name': 'Hisashi Fujioka', 'orcid': 'https://orcid.org/0000-0001-8511-7141'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'H Fujioka', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043825919', 'display_name': 'David B. Keister', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D B Keister', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083887946', 'display_name': 'Olga Muratova', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'O Muratova', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011187406', 'display_name': 'David C. Kaslow', 'orcid': 'https://orcid.org/0000-0003-3557-383X'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D C Kaslow', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064861833', 'display_name': 'Masanori Aikawa', 'orcid': 'https://orcid.org/0000-0002-9275-2079'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M Aikawa', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050162568', 'display_name': 'Akhil B. Vaidya', 'orcid': 'https://orcid.org/0000-0003-1063-5571'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'A B Vaidya', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067549205', 'display_name': 'Thomas E. Wellems', 'orcid': 'https://orcid.org/0000-0003-3899-8454'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T E Wellems', 'raw_affiliation_strings': ['Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-0425, USA.', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.899, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 57, 'citation_normalized_percentile': {'value': 0.955626, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '135', 'issue': '1', 'first_page': '269', 'last_page': '278'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11403', 'display_name': 'Invertebrate Immune Response Mechanisms', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10166', 'display_name': 'Mosquito-borne diseases and control', 'score': 0.9881, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/clone', 'display_name': 'clone (Java method)', 'score': 0.53396136}, {'id': 'https://openalex.org/keywords/infectivity', 'display_name': 'Infectivity', 'score': 0.4620824}, {'id': 'https://openalex.org/keywords/plasmodium', 'display_name': 'Plasmodium (life cycle)', 'score': 0.44269603}], 'concepts': [{'id': 'https://openalex.org/C99389464', 'wikidata': 'https://www.wikidata.org/wiki/Q3319949', 'display_name': 'Gametocyte', 'level': 4, 'score': 0.98224556}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.9679478}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.7285675}, {'id': 'https://openalex.org/C39297687', 'wikidata': 'https://www.wikidata.org/wiki/Q1410510', 'display_name': 'Gametogenesis', 'level': 4, 'score': 0.690144}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.555873}, {'id': 'https://openalex.org/C81089528', 'wikidata': 'https://www.wikidata.org/wiki/Q5134986', 'display_name': 'clone (Java method)', 'level': 3, 'score': 0.53396136}, {'id': 'https://openalex.org/C106358424', 'wikidata': 'https://www.wikidata.org/wiki/Q1662346', 'display_name': 'Infectivity', 'level': 3, 'score': 0.4620824}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.4464636}, {'id': 'https://openalex.org/C2778675580', 'wikidata': 'https://www.wikidata.org/wiki/Q614956', 'display_name': 'Plasmodium (life cycle)', 'level': 3, 'score': 0.44269603}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.33864164}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2751128}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.15596864}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.155011}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.11943039}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.097765565}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000852', 'descriptor_name': 'Anopheles', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D000852', 'descriptor_name': 'Anopheles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016172', 'descriptor_name': 'DNA Fingerprinting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005718', 'descriptor_name': 'Gametogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015767', 'descriptor_name': 'Mefloquine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012150', 'descriptor_name': 'Polymorphism, Restriction Fragment Length', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D014404', 'descriptor_name': 'Tubulin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014617', 'descriptor_name': 'Vacuoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.135.1.269', 'pdf_url': 'http://jcb.rupress.org/content/135/1/269.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2121010', 'pdf_url': 'https://europepmc.org/articles/pmc2121010?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8858179', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.135.1.269', 'pdf_url': 'http://jcb.rupress.org/content/135/1/269.full.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.54, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W13897609', 'https://openalex.org/W1572126472', 'https://openalex.org/W1838568970', 'https://openalex.org/W1917144541', 'https://openalex.org/W1931739120', 'https://openalex.org/W1964408180', 'https://openalex.org/W1969503178', 'https://openalex.org/W1974527939', 'https://openalex.org/W1980752431', 'https://openalex.org/W1985134771', 'https://openalex.org/W1989847776', 'https://openalex.org/W1991261293', 'https://openalex.org/W1991504685', 'https://openalex.org/W1993051795', 'https://openalex.org/W1993741644', 'https://openalex.org/W1994983502', 'https://openalex.org/W1996079166', 'https://openalex.org/W1998770998', 'https://openalex.org/W1999417874', 'https://openalex.org/W2001102860', 'https://openalex.org/W2014337577', 'https://openalex.org/W2015107346', 'https://openalex.org/W2016102145', 'https://openalex.org/W2016203598', 'https://openalex.org/W2027073862', 'https://openalex.org/W2028105781', 'https://openalex.org/W2029229088', 'https://openalex.org/W2033653481', 'https://openalex.org/W2037081223', 'https://openalex.org/W2048948813', 'https://openalex.org/W2053558413', 'https://openalex.org/W2057721736', 'https://openalex.org/W2062303707', 'https://openalex.org/W2062422172', 'https://openalex.org/W2071519714', 'https://openalex.org/W2077163521', 'https://openalex.org/W2078811617', 'https://openalex.org/W2080614201', 'https://openalex.org/W2081449889', 'https://openalex.org/W2089067969', 'https://openalex.org/W2090082914', 'https://openalex.org/W2101144468', 'https://openalex.org/W2147775888', 'https://openalex.org/W4236359835', 'https://openalex.org/W4248670775', 'https://openalex.org/W596350362'], 'related_works': ['https://openalex.org/W4281637788', 'https://openalex.org/W2782324300', 'https://openalex.org/W2413981943', 'https://openalex.org/W2413009189', 'https://openalex.org/W2396833167', 'https://openalex.org/W2122430741', 'https://openalex.org/W2092201106', 'https://openalex.org/W2047211645', 'https://openalex.org/W2019466471', 'https://openalex.org/W2000481478'], 'abstract_inverted_index': {'Asexually': [0], 'replicating': [1], 'populations': [2], 'of': [3, 28, 36, 46, 59, 75, 83, 88, 115, 138, 154, 168, 187, 208, 224, 229], 'Plasmodium': [4], 'parasites,': [5], 'including': [6], 'those': [7], 'from': [8, 38, 79, 96], 'cloned': [9], 'lines,': [10], 'generate': [11], 'both': [12], 'male': [13, 77, 139, 156, 189, 202, 210, 225], 'and': [14, 57, 121, 125, 175, 228, 241], 'female': [15], 'gametes': [16], 'to': [17, 92, 163, 201, 219, 231], 'complete': [18, 222], 'the': [19, 24, 34, 44, 47, 55, 60, 73, 89, 93, 104, 112, 142, 152, 159, 182, 235], 'malaria': [20], 'life': [21], 'cycle': [22], 'through': [23], 'mosquito.': [25], 'The': [26, 50, 184, 214], 'generation': [27], 'these': [29], 'sexual': [30, 61], 'forms': [31, 62], 'begins': [32], 'with': [33, 129, 145, 181], 'induction': [35], 'gametocytes': [37, 78, 157, 190, 211], 'haploid': [39], 'asexual': [40, 116], 'stage': [41], 'parasites': [42], 'in': [43, 118, 151, 195, 243], 'blood': [45], 'vertebrate': [48], 'host.': [49], 'molecular': [51], 'processes': [52, 196], 'that': [53, 71, 103, 109, 197], 'govern': [54], 'differentiation': [56], 'development': [58, 74, 140, 203], 'are': [63], 'largely': [64], 'unknown.': [65], 'Here': [66], 'we': [67], 'describe': [68], 'a': [69, 80, 107, 135, 148, 193, 199, 205], 'defect': [70, 105, 215], 'affects': [72], 'competent': [76], 'mutant': [81], 'clone': [82, 91, 95, 161], 'P.': [84], 'falciparum': [85], '(Dd2).': [86], 'Comparison': [87], 'Dd2': [90, 160], 'predecessor': [94], 'which': [97], 'it': [98], 'was': [99], 'derived': [100], "(W2'82)": [101], 'shows': [102], 'is': [106, 179, 216, 234], 'mutation': [108, 239], 'arose': [110], 'during': [111, 212], 'long-term': [113], 'cultivation': [114], 'stages': [117], 'vitro.': [119], 'Light': [120], 'electron': [122], 'microscopic': [123], 'images,': [124], 'indirect': [126], 'immunofluorescence': [127], 'assays': [128], 'male-specific': [130], 'anti-alpha-tubulin': [131], 'II': [132], 'antibodies,': [133], 'indicate': [134], 'global': [136], 'disruption': [137], 'at': [141, 146], 'gametocyte': [143, 170, 200], 'level': [144], 'least': [147], '70-90%': [149], 'reduction': [150], 'proportion': [153], 'mature': [155, 188], 'by': [158], 'relative': [162], "W2'82.": [164], 'A': [165], 'high': [166], 'prevalence': [167], 'abnormal': [169], 'forms,': [171], 'frequently': [172], 'containing': [173], 'multiple': [174], 'unusually': [176], 'large': [177], 'vacuoles,': [178], 'associated': [180], 'defect.': [183], 'reduced': [185], 'production': [186, 227], 'may': [191], 'reflect': [192], 'problem': [194], 'commit': [198], 'or': [204], 'progressive': [206], 'attrition': [207], 'viable': [209], 'maturation.': [213], 'genetically': [217], 'linked': [218], 'an': [220], 'almost': [221], 'absence': [223], 'gamete': [226], 'infectivity': [230], 'mosquitoes.': [232], 'This': [233], 'first': [236], 'sex-specific': [237], 'developmental': [238], 'identified': [240], 'characterized': [242], 'Plasmodium.': [244]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2121826111', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-10T18:23:42.591320', 'created_date': '2016-06-24'}