The stepwise two‐photon excited melanin fluorescence is a unique diagnostic tool for the detection of malignant transformation in melanocytes

Name: Work Video:
Duration: 3 min 30 s
D. Leupold; M. Scholz; Goran Stanković; Julian Reda; Susanne Buder; Reinhold Eichhorn; Gert Wessler; Markus Stücker; Klaus Hoffmann; Jürgen Bauer; Claus Garbe
{'id': 'https://openalex.org/W2121706068', 'doi': 'https://doi.org/10.1111/j.1755-148x.2011.00853.x', 'title': 'The stepwise two‐photon excited melanin fluorescence is a unique diagnostic tool for the detection of malignant transformation in melanocytes', 'display_name': 'The stepwise two‐photon excited melanin fluorescence is a unique diagnostic tool for the detection of malignant transformation in melanocytes', 'publication_year': 2011, 'publication_date': '2011-04-02', 'ids': {'openalex': 'https://openalex.org/W2121706068', 'doi': 'https://doi.org/10.1111/j.1755-148x.2011.00853.x', 'mag': '2121706068', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21457482'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1755-148x.2011.00853.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S179442820', 'display_name': 'Pigment Cell & Melanoma Research', 'issn_l': '1755-1471', 'issn': ['1755-1471', '1755-148X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109982661', 'display_name': 'D. Leupold', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150207', 'display_name': 'Laser- und Medizin-Technologie (Germany)', 'ror': 'https://ror.org/03j1srb55', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I4210150207']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Dieter Leupold', 'raw_affiliation_strings': ['LTB Lasertechnik Berlin, Berlin, Germany.'], 'affiliations': [{'raw_affiliation_string': 'LTB Lasertechnik Berlin, Berlin, Germany.', 'institution_ids': ['https://openalex.org/I4210150207']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043859146', 'display_name': 'M. Scholz', 'orcid': 'https://orcid.org/0000-0002-4300-3020'}, 'institutions': [{'id': 'https://openalex.org/I4210150207', 'display_name': 'Laser- und Medizin-Technologie (Germany)', 'ror': 'https://ror.org/03j1srb55', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I4210150207']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Matthias Scholz', 'raw_affiliation_strings': ['LTB Lasertechnik Berlin, Berlin, Germany.'], 'affiliations': [{'raw_affiliation_string': 'LTB Lasertechnik Berlin, Berlin, Germany.', 'institution_ids': ['https://openalex.org/I4210150207']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049648116', 'display_name': 'Goran Stanković', 'orcid': 'https://orcid.org/0000-0002-9414-0885'}, 'institutions': [{'id': 'https://openalex.org/I4210150207', 'display_name': 'Laser- und Medizin-Technologie (Germany)', 'ror': 'https://ror.org/03j1srb55', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I4210150207']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Goran Stankovic', 'raw_affiliation_strings': ['LTB Lasertechnik Berlin, Berlin, Germany.'], 'affiliations': [{'raw_affiliation_string': 'LTB Lasertechnik Berlin, Berlin, Germany.', 'institution_ids': ['https://openalex.org/I4210150207']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001185557', 'display_name': 'Julian Reda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150207', 'display_name': 'Laser- und Medizin-Technologie (Germany)', 'ror': 'https://ror.org/03j1srb55', 'country_code': 'DE', 'type': 'company', 'lineage': ['https://openalex.org/I4210150207']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Julian Reda', 'raw_affiliation_strings': ['LTB Lasertechnik Berlin, Berlin, Germany.'], 'affiliations': [{'raw_affiliation_string': 'LTB Lasertechnik Berlin, Berlin, Germany.', 'institution_ids': ['https://openalex.org/I4210150207']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036645430', 'display_name': 'Susanne Buder', 'orcid': 'https://orcid.org/0000-0002-5878-7892'}, 'institutions': [{'id': 'https://openalex.org/I4210109729', 'display_name': 'Vivantes Klinikum', 'ror': 'https://ror.org/01x29t295', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210109729']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Susanne Buder', 'raw_affiliation_strings': ['Vivantes Klinikum Neukölln, Klinik für Dermatologie und Venerologie, Berlin, Germany'], 'affiliations': [{'raw_affiliation_string': 'Vivantes Klinikum Neukölln, Klinik für Dermatologie und Venerologie, Berlin, Germany', 'institution_ids': ['https://openalex.org/I4210109729']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047782951', 'display_name': 'Reinhold Eichhorn', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210142289', 'display_name': 'MVZ - Kurfürstendamm', 'ror': 'https://ror.org/05agddf32', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210142289']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Reinhold Eichhorn', 'raw_affiliation_strings': ['Praxis für Dermatologie, Kurfürstendamm, Berlin, Germany'], 'affiliations': [{'raw_affiliation_string': 'Praxis für Dermatologie, Kurfürstendamm, Berlin, Germany', 'institution_ids': ['https://openalex.org/I4210142289']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042189516', 'display_name': 'Gert Wessler', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210142289', 'display_name': 'MVZ - Kurfürstendamm', 'ror': 'https://ror.org/05agddf32', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210142289']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Gert Wessler', 'raw_affiliation_strings': ['Praxis für Dermatologie, Kurfürstendamm, Berlin, Germany'], 'affiliations': [{'raw_affiliation_string': 'Praxis für Dermatologie, Kurfürstendamm, Berlin, Germany', 'institution_ids': ['https://openalex.org/I4210142289']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086486271', 'display_name': 'Markus Stücker', 'orcid': 'https://orcid.org/0000-0001-5564-5285'}, 'institutions': [{'id': 'https://openalex.org/I4210138993', 'display_name': 'St. Josef-Hospital', 'ror': 'https://ror.org/046vare28', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799784675', 'https://openalex.org/I4210138993', 'https://openalex.org/I4210153564']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Markus Stücker', 'raw_affiliation_strings': ['Ruhr-Universität Bochum, Klinik für Dermatologie, St. Josef Hospital, Bochum, Germany'], 'affiliations': [{'raw_affiliation_string': 'Ruhr-Universität Bochum, Klinik für Dermatologie, St. Josef Hospital, Bochum, Germany', 'institution_ids': ['https://openalex.org/I4210138993']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110680144', 'display_name': 'Klaus Hoffmann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210138993', 'display_name': 'St. Josef-Hospital', 'ror': 'https://ror.org/046vare28', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799784675', 'https://openalex.org/I4210138993', 'https://openalex.org/I4210153564']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Klaus Hoffmann', 'raw_affiliation_strings': ['Ruhr-Universität Bochum, Klinik für Dermatologie, St. Josef Hospital, Bochum, Germany'], 'affiliations': [{'raw_affiliation_string': 'Ruhr-Universität Bochum, Klinik für Dermatologie, St. Josef Hospital, Bochum, Germany', 'institution_ids': ['https://openalex.org/I4210138993']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043675557', 'display_name': 'Jürgen Bauer', 'orcid': 'https://orcid.org/0000-0001-8789-1536'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Jürgen Bauer', 'raw_affiliation_strings': ['Universität Tübingen, Universitäts‐Hautklinik, Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Universität Tübingen, Universitäts‐Hautklinik, Tübingen, Germany', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001548963', 'display_name': 'Claus Garbe', 'orcid': 'https://orcid.org/0000-0001-8530-780X'}, 'institutions': [], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Claus Garbe', 'raw_affiliation_strings': ['Universität Tübingen, Universitäts‐Hautklinik, Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Universität Tübingen, Universitäts‐Hautklinik, Tübingen, Germany', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4530, 'currency': 'USD', 'value_usd': 4530, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.919, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.999878, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '24', 'issue': '3', 'first_page': '438', 'last_page': '445'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11144', 'display_name': 'melanin and skin pigmentation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11144', 'display_name': 'melanin and skin pigmentation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10957', 'display_name': 'Photodynamic Therapy Research Studies', 'score': 0.9969, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11013', 'display_name': 'Skin Protection and Aging', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/2708', 'display_name': 'Dermatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/autofluorescence', 'display_name': 'Autofluorescence', 'score': 0.7035029}, {'id': 'https://openalex.org/keywords/malignant-transformation', 'display_name': 'Malignant Transformation', 'score': 0.60197866}, {'id': 'https://openalex.org/keywords/two-photon-excitation-microscopy', 'display_name': 'Two-photon excitation microscopy', 'score': 0.43165532}], 'concepts': [{'id': 'https://openalex.org/C107538193', 'wikidata': 'https://www.wikidata.org/wiki/Q187526', 'display_name': 'Melanin', 'level': 2, 'score': 0.85902977}, {'id': 'https://openalex.org/C2777658100', 'wikidata': 'https://www.wikidata.org/wiki/Q180614', 'display_name': 'Melanoma', 'level': 2, 'score': 0.76562107}, {'id': 'https://openalex.org/C91881484', 'wikidata': 'https://www.wikidata.org/wiki/Q191807', 'display_name': 'Fluorescence', 'level': 2, 'score': 0.74508244}, {'id': 'https://openalex.org/C179687394', 'wikidata': 'https://www.wikidata.org/wiki/Q4826281', 'display_name': 'Autofluorescence', 'level': 3, 'score': 0.7035029}, {'id': 'https://openalex.org/C31033888', 'wikidata': 'https://www.wikidata.org/wiki/Q752076', 'display_name': 'Malignant transformation', 'level': 2, 'score': 0.60197866}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4619589}, {'id': 'https://openalex.org/C47785574', 'wikidata': 'https://www.wikidata.org/wiki/Q373859', 'display_name': 'Two-photon excitation microscopy', 'level': 3, 'score': 0.43165532}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3851436}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.24675539}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.18774173}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18496898}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.11699808}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10427815}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.059316993}], 'mesh': [{'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009508', 'descriptor_name': 'Nevus, Pigmented', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012878', 'descriptor_name': 'Skin Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008545', 'descriptor_name': 'Melanoma', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D009508', 'descriptor_name': 'Nevus, Pigmented', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009508', 'descriptor_name': 'Nevus, Pigmented', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D012878', 'descriptor_name': 'Skin Neoplasms', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D012878', 'descriptor_name': 'Skin Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013050', 'descriptor_name': 'Spectrometry, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1755-148x.2011.00853.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S179442820', 'display_name': 'Pigment Cell & Melanoma Research', 'issn_l': '1755-1471', 'issn': ['1755-1471', '1755-148X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21457482', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W161968958', 'https://openalex.org/W1966820518', 'https://openalex.org/W1995034206', 'https://openalex.org/W1999898032', 'https://openalex.org/W2006119091', 'https://openalex.org/W2015053497', 'https://openalex.org/W2022205990', 'https://openalex.org/W2022212425', 'https://openalex.org/W2033020960', 'https://openalex.org/W2035429965', 'https://openalex.org/W2050870644', 'https://openalex.org/W2060552070', 'https://openalex.org/W2067533505', 'https://openalex.org/W2068689596', 'https://openalex.org/W2074457543', 'https://openalex.org/W2079787990', 'https://openalex.org/W2089519100', 'https://openalex.org/W2111829859', 'https://openalex.org/W2119588751', 'https://openalex.org/W2156099567', 'https://openalex.org/W2408669498', 'https://openalex.org/W2588476369', 'https://openalex.org/W4244064223'], 'related_works': ['https://openalex.org/W4362634222', 'https://openalex.org/W314314331', 'https://openalex.org/W3107520317', 'https://openalex.org/W2953403851', 'https://openalex.org/W2413853751', 'https://openalex.org/W2394994671', 'https://openalex.org/W2140197046', 'https://openalex.org/W2048662511', 'https://openalex.org/W2027376101', 'https://openalex.org/W1811562979'], 'abstract_inverted_index': {'Malignant': [0], 'transformation': [1], 'of': [2, 12, 19, 27, 59, 66, 78, 110, 125, 141, 148, 158], 'melanocytes': [3], 'is': [4, 32, 43, 180], 'associated': [5], 'with': [6, 101, 151], 'changes': [7], 'in': [8, 29, 38, 131, 187], 'melanogenesis.': [9], 'Therefore,': [10], 'fluorescence': [11, 49, 64, 76, 103, 116, 133, 178], 'melanin': [13, 28, 75, 115], 'may': [14, 186], 'be': [15], 'an': [16], 'informative': [17], 'indicator': [18], 'this': [20, 159], 'process.': [21], 'But': [22], 'the': [23, 39, 46, 111, 132, 156, 167, 171], 'conventionally': [24], 'excited': [25], 'autofluorescence': [26], 'skin': [30, 68], 'tissue': [31], 'ultra-weak': [33], 'and': [34, 84, 143, 154, 170], 'its': [35], 'main': [36], 'part': [37], 'visible': [40], 'spectral': [41, 94], 'region': [42], 'hidden': [44], 'by': [45], 'much': [47], 'stronger': [48], 'from': [50], 'other': [51], 'endogenous': [52], 'fluorophores.': [53], 'Here,': [54], 'using': [55], 'a': [56, 98, 102, 146, 181], 'new': [57, 160, 182], 'mode': [58], 'stepwise': [60], 'two-photon': [61, 176], 'excitation,': [62], 'melanin-dominated': [63], 'spectra': [65, 77, 117, 134], 'pigmented': [67, 80, 86], 'lesions': [69], 'are': [70, 135], 'reported.': [71], 'From': [72], 'these,': [73], 'pure': [74], 'normal': [79], 'skin,': [81], 'melanocytic': [82, 127, 152], 'nevi': [83, 153], 'malignant': [85], 'melanoma': [87, 96, 112, 164], 'were': [88], 'analyzed.': [89], 'They': [90], 'show': [91], 'distinctly': [92], 'different': [93, 139], 'shapes:': [95], 'gave': [97], 'characteristic': [99], 'fingerprint': [100], 'band': [104], 'peaking': [105], 'at': [106, 119], '640': [107], 'nm,': [108], 'independent': [109], 'subtype.': [113], 'The': [114, 175], 'peaked': [118], '590': [120], 'nm': [121], 'for': [122], 'all': [123], 'types': [124], 'common': [126], 'nevi.': [128], 'These': [129], 'differences': [130], 'probably': [136], 'based': [137], 'on': [138], 'contents': [140], 'eumelanin': [142], 'pheomelanin.': [144], 'In': [145], 'series': [147], '167': [149], 'cases': [150], 'melanomas,': [155], 'sensitivity': [157], 'method': [161, 179], 'to': [162], 'diagnose': [163], 'was': [165], '93.5%,': [166], 'specificity': [168], '80.0%': [169], 'diagnostic': [172, 183], 'accuracy': [173], '82.6%.': [174], 'excitation': [177], 'tool': [184], 'which': [185], 'future': [188], 'supplement': [189], 'conventional': [190], 'dermatohistopathology.': [191]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2121706068', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-17T12:46:44.040767', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
