Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2120439612', 'doi': 'https://doi.org/10.1101/gad.605910', 'title': 'Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes', 'display_name': 'Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes', 'publication_year': 2010, 'publication_date': '2010-10-22', 'ids': {'openalex': 'https://openalex.org/W2120439612', 'doi': 'https://doi.org/10.1101/gad.605910', 'mag': '2120439612', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20971813', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2975927'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.605910', 'pdf_url': 'http://genesdev.cshlp.org/content/24/22/2505.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://genesdev.cshlp.org/content/24/22/2505.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5058565694', 'display_name': 'Kikuë Tachibana-Konwalski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Kikuë Tachibana-Konwalski', 'raw_affiliation_strings': ['Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035866336', 'display_name': 'Jonathan Godwin', 'orcid': 'https://orcid.org/0000-0002-0738-6247'}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Jonathan Godwin', 'raw_affiliation_strings': ['Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021154491', 'display_name': 'Louise van der Weyden', 'orcid': 'https://orcid.org/0000-0002-0645-1879'}, 'institutions': [{'id': 'https://openalex.org/I2802476451', 'display_name': 'Wellcome Sanger Institute', 'ror': 'https://ror.org/05cy4wa09', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802476451', 'https://openalex.org/I87048295']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Louise van der Weyden', 'raw_affiliation_strings': ['Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom', 'institution_ids': ['https://openalex.org/I2802476451']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015967626', 'display_name': 'Lysie Champion', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Lysie Champion', 'raw_affiliation_strings': ['Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046604348', 'display_name': 'N. Kudo', 'orcid': 'https://orcid.org/0000-0001-8134-1242'}, 'institutions': [{'id': 'https://openalex.org/I47508984', 'display_name': 'Imperial College London', 'ror': 'https://ror.org/041kmwe10', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I47508984']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Nobuaki R. Kudo', 'raw_affiliation_strings': ['Institute of Reproductive and Developmental Biology, Imperial College London, London W12 0NN, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Institute of Reproductive and Developmental Biology, Imperial College London, London W12 0NN, United Kingdom', 'institution_ids': ['https://openalex.org/I47508984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102865320', 'display_name': 'David J. Adams', 'orcid': 'https://orcid.org/0000-0001-9490-0306'}, 'institutions': [{'id': 'https://openalex.org/I2802476451', 'display_name': 'Wellcome Sanger Institute', 'ror': 'https://ror.org/05cy4wa09', 'country_code': 'GB', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802476451', 'https://openalex.org/I87048295']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'David J. Adams', 'raw_affiliation_strings': ['Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom', 'institution_ids': ['https://openalex.org/I2802476451']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025297651', 'display_name': 'Kim Nasmyth', 'orcid': 'https://orcid.org/0000-0001-7030-4403'}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Kim Nasmyth', 'raw_affiliation_strings': ['Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom', 'institution_ids': ['https://openalex.org/I40120149']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 8.302, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 247, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '24', 'issue': '22', 'first_page': '2505', 'last_page': '2516'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10222', 'display_name': 'Regulation of Chromatin Structure and Function', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10222', 'display_name': 'Regulation of Chromatin Structure and Function', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10978', 'display_name': 'Prenatal Aneuploidy Diagnosis and Screening Techniques', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10364', 'display_name': 'Fertility Preservation in Cancer Patients', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/separase', 'display_name': 'Separase', 'score': 0.78670955}, {'id': 'https://openalex.org/keywords/meiosis-ii', 'display_name': 'Meiosis II', 'score': 0.6016834}, {'id': 'https://openalex.org/keywords/meiocyte', 'display_name': 'Meiocyte', 'score': 0.4856952}, {'id': 'https://openalex.org/keywords/trisomy-detection', 'display_name': 'Trisomy Detection', 'score': 0.475212}, {'id': 'https://openalex.org/keywords/bivalent', 'display_name': 'Bivalent (engine)', 'score': 0.45571613}], 'concepts': [{'id': 'https://openalex.org/C115821613', 'wikidata': 'https://www.wikidata.org/wiki/Q21103063', 'display_name': 'Cohesin', 'level': 4, 'score': 0.97157764}, {'id': 'https://openalex.org/C152369539', 'wikidata': 'https://www.wikidata.org/wiki/Q5399999', 'display_name': 'Establishment of sister chromatid cohesion', 'level': 5, 'score': 0.88213885}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.79441}, {'id': 'https://openalex.org/C136322937', 'wikidata': 'https://www.wikidata.org/wiki/Q22676914', 'display_name': 'Separase', 'level': 5, 'score': 0.78670955}, {'id': 'https://openalex.org/C8502773', 'wikidata': 'https://www.wikidata.org/wiki/Q2066168', 'display_name': 'Sister chromatids', 'level': 4, 'score': 0.64375985}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.60179514}, {'id': 'https://openalex.org/C2910992960', 'wikidata': 'https://www.wikidata.org/wiki/Q21100485', 'display_name': 'Meiosis II', 'level': 4, 'score': 0.6016834}, {'id': 'https://openalex.org/C73397532', 'wikidata': 'https://www.wikidata.org/wiki/Q623749', 'display_name': 'Chromatid', 'level': 4, 'score': 0.58694625}, {'id': 'https://openalex.org/C2778354886', 'wikidata': 'https://www.wikidata.org/wiki/Q5113927', 'display_name': 'Chromosome segregation', 'level': 4, 'score': 0.5653065}, {'id': 'https://openalex.org/C148196450', 'wikidata': 'https://www.wikidata.org/wiki/Q21100485', 'display_name': 'Meiosis', 'level': 3, 'score': 0.5462574}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.5098728}, {'id': 'https://openalex.org/C139077094', 'wikidata': 'https://www.wikidata.org/wiki/Q6810199', 'display_name': 'Meiocyte', 'level': 4, 'score': 0.4856952}, {'id': 'https://openalex.org/C63491729', 'wikidata': 'https://www.wikidata.org/wiki/Q14762596', 'display_name': 'Centromere', 'level': 4, 'score': 0.4619418}, {'id': 'https://openalex.org/C2776620830', 'wikidata': 'https://www.wikidata.org/wiki/Q4919211', 'display_name': 'Bivalent (engine)', 'level': 3, 'score': 0.45571613}, {'id': 'https://openalex.org/C2776690073', 'wikidata': 'https://www.wikidata.org/wiki/Q3246226', 'display_name': 'Oocyte', 'level': 3, 'score': 0.32721466}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.2016412}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.18604523}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.08535358}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C544153396', 'wikidata': 'https://www.wikidata.org/wiki/Q11426', 'display_name': 'Metal', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002875', 'descriptor_name': 'Chromosomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009865', 'descriptor_name': 'Oocytes', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D009865', 'descriptor_name': 'Oocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018797', 'descriptor_name': 'Cell Cycle Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002503', 'descriptor_name': 'Centromere', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002503', 'descriptor_name': 'Centromere', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002875', 'descriptor_name': 'Chromosomes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002875', 'descriptor_name': 'Chromosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000097722', 'descriptor_name': 'Cohesins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010450', 'descriptor_name': 'Endopeptidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010450', 'descriptor_name': 'Endopeptidases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009865', 'descriptor_name': 'Oocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.605910', 'pdf_url': 'http://genesdev.cshlp.org/content/24/22/2505.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2975927', 'pdf_url': 'https://europepmc.org/articles/pmc2975927?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975927', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20971813', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.605910', 'pdf_url': 'http://genesdev.cshlp.org/content/24/22/2505.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1517524597', 'https://openalex.org/W1529934215', 'https://openalex.org/W1968374826', 'https://openalex.org/W1971801697', 'https://openalex.org/W1982367970', 'https://openalex.org/W1983077985', 'https://openalex.org/W1983579777', 'https://openalex.org/W1993079403', 'https://openalex.org/W1997226150', 'https://openalex.org/W1997528931', 'https://openalex.org/W1997579482', 'https://openalex.org/W1998402274', 'https://openalex.org/W1998498391', 'https://openalex.org/W2008553523', 'https://openalex.org/W2012212160', 'https://openalex.org/W2013069561', 'https://openalex.org/W2023411715', 'https://openalex.org/W2031847595', 'https://openalex.org/W2032629746', 'https://openalex.org/W2036428969', 'https://openalex.org/W2040433610', 'https://openalex.org/W2042400521', 'https://openalex.org/W2050183773', 'https://openalex.org/W2051502996', 'https://openalex.org/W2056681619', 'https://openalex.org/W2056775659', 'https://openalex.org/W2062058774', 'https://openalex.org/W2065176180', 'https://openalex.org/W2067755197', 'https://openalex.org/W2068493953', 'https://openalex.org/W2070048674', 'https://openalex.org/W2071828467', 'https://openalex.org/W2072306817', 'https://openalex.org/W2076443479', 'https://openalex.org/W2078427400', 'https://openalex.org/W2078743927', 'https://openalex.org/W2080569159', 'https://openalex.org/W2081567987', 'https://openalex.org/W2085064256', 'https://openalex.org/W2087433592', 'https://openalex.org/W2093342789', 'https://openalex.org/W2106624058', 'https://openalex.org/W2108688550', 'https://openalex.org/W2109556015', 'https://openalex.org/W2110691960', 'https://openalex.org/W2116045064', 'https://openalex.org/W2118746619', 'https://openalex.org/W2127000489', 'https://openalex.org/W2132401094', 'https://openalex.org/W2140525749', 'https://openalex.org/W2144994329', 'https://openalex.org/W2146646972', 'https://openalex.org/W2150566170', 'https://openalex.org/W2155866830', 'https://openalex.org/W2157535919', 'https://openalex.org/W2160473082', 'https://openalex.org/W2168405417', 'https://openalex.org/W2169441156', 'https://openalex.org/W2178193052', 'https://openalex.org/W2461932887', 'https://openalex.org/W4249572383'], 'related_works': ['https://openalex.org/W4214853505', 'https://openalex.org/W2951286008', 'https://openalex.org/W2810161206', 'https://openalex.org/W2802421362', 'https://openalex.org/W2612078432', 'https://openalex.org/W2120439612', 'https://openalex.org/W2072306817', 'https://openalex.org/W1989978653', 'https://openalex.org/W1971117976', 'https://openalex.org/W1966478901'], 'abstract_inverted_index': {'During': [0], 'female': [1], 'meiosis,': [2], 'bivalent': [3, 148], 'chromosomes': [4], 'are': [5], 'thought': [6], 'to': [7, 125, 169, 174], 'be': [8, 77], 'held': [9], 'together': [10, 64], 'from': [11, 123], 'birth': [12], 'until': [13], 'ovulation': [14], 'by': [15, 20, 79, 84], 'sister': [16, 101, 111], 'chromatid': [17, 112], 'cohesion': [18, 35, 171], 'mediated': [19], 'cohesin': [21, 53, 61, 127, 154], 'complexes': [22], 'whose': [23, 73], 'ring': [24], 'structure': [25], 'depends': [26], 'on': [27], 'kleisin': [28, 74], 'subunits,': [29], 'either': [30], 'Rec8': [31, 92, 135], 'or': [32, 59, 152], 'Scc1.': [33], 'Because': [34], 'is': [36], 'established': [37], 'at': [38, 128], 'DNA': [39], 'replication': [40], 'in': [41, 114], 'the': [42, 115, 138, 165], 'embryo,': [43], 'its': [44], 'maintenance': [45], 'for': [46, 156], 'such': [47], 'a': [48, 120], 'long': [49], 'time': [50], 'may': [51, 172], 'require': [52], 'turnover.': [54], 'To': [55], 'address': [56], 'whether': [57, 66], 'Rec8-': [58, 124], 'Scc1-containing': [60, 126], 'holds': [62], 'bivalents': [63], 'and': [65, 87, 100], 'it': [67], 'turns': [68], 'over,': [69], 'we': [70], 'created': [71], 'mice': [72], 'subunits': [75], 'can': [76], 'cleaved': [78], 'TEV': [80], 'protease.': [81], 'We': [82, 162], 'show': [83], 'microinjection': [85], 'experiments': [86], 'confocal': [88], 'live-cell': [89], 'imaging': [90], 'that': [91, 164], 'cleavage': [93, 109], 'triggers': [94, 110], 'chiasmata': [95], 'resolution': [96], 'during': [97, 104, 137, 159], 'meiosis': [98, 105, 176], 'I': [99, 177], 'centromere': [102], 'disjunction': [103, 113], 'II,': [106], 'while': [107], 'Scc1': [108], 'first': [116], 'embryonic': [117], 'mitosis,': [118], 'demonstrating': [119], 'dramatic': [121], 'transition': [122], 'fertilization.': [129], 'Crucially,': [130], 'activation': [131], 'of': [132, 141, 167], 'an': [133], 'ectopic': [134], 'transgene': [136], 'growing': [139], 'phase': [140], 'Rec8(TEV)(/TEV)': [142], 'oocytes': [143, 168], 'does': [144], 'not': [145], 'prevent': [146], 'TEV-mediated': [147], 'destruction,': [149], 'implying': [150], 'little': [151], 'no': [153], 'turnover': [155], '≥2': [157], 'wk': [158], 'oocyte': [160], 'growth.': [161], 'suggest': [163], 'inability': [166], 'regenerate': [170], 'contribute': [173], 'age-related': [175], 'errors.': [178]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2120439612', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 14}, {'year': 2021, 'cited_by_count': 21}, {'year': 2020, 'cited_by_count': 18}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 17}, {'year': 2017, 'cited_by_count': 30}, {'year': 2016, 'cited_by_count': 18}, {'year': 2015, 'cited_by_count': 17}, {'year': 2014, 'cited_by_count': 13}, {'year': 2013, 'cited_by_count': 22}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2024-09-10T01:48:42.844551', 'created_date': '2016-06-24'}