Publication Information

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'https://openalex.org/W1979207410', 'https://openalex.org/W1948440799'], 'abstract_inverted_index': {'In': [0, 122, 175, 297, 850, 1389, 1812, 1868, 1909, 2243, 2373, 2935, 3474, 3830, 3886, 3927, 4261, 4391, 4486, 5027, 5289, 5345, 5386, 5612, 5647], 'mammals,': [1, 176], 'the': [2, 28, 32, 58, 62, 89, 94, 100, 129, 161, 166, 177, 203, 207, 233, 237, 264, 269, 275, 304, 336, 341, 352, 357, 370, 452, 507, 516, 527, 530, 539, 547, 641, 648, 694, 731, 746, 775, 791, 795, 819, 829, 842, 846, 853, 880, 1052, 1079, 1171, 1179, 1234, 1277, 1282, 1289, 1360, 1531, 1535, 1540, 1544, 1566, 1569, 1630, 1634, 1643, 1659, 1667, 1699, 1738, 1760, 1814, 1833, 1956, 1972, 1981, 2002, 2019, 2029, 2036, 2046, 2050, 2055, 2102, 2107, 2129, 2150, 2232, 2256, 2285, 2311, 2343, 2350, 2376, 2415, 2436, 2441, 2454, 2536, 2591, 2600, 2611, 2614, 2623, 2631, 2725, 2732, 2778, 2815, 2830, 2859, 2875, 2879, 2904, 2914, 2927, 2931, 2938, 2965, 3137, 3164, 3256, 3264, 3319, 3362, 3367, 3374, 3445, 3549, 3553, 3558, 3562, 3584, 3587, 3648, 3652, 3661, 3677, 3685, 3717, 3756, 3778, 3832, 3851, 3974, 3990, 3999, 4020, 4037, 4047, 4054, 4064, 4068, 4073, 4120, 4125, 4147, 4168, 4250, 4274, 4303, 4329, 4361, 4368, 4394, 4433, 4455, 4465, 4478, 4482, 4489, 4516, 4689, 4716, 4808, 4816, 4871, 4914, 4919, 4926, 4998, 5103, 5107, 5112, 5116, 5138, 5141, 5176, 5215, 5237, 5291, 5310, 5433, 5449, 5458, 5479, 5496, 5506, 5513, 5523, 5527, 5532, 5579, 5584, 5606, 5617, 5624, 5650, 5689, 5711, 5720, 5724, 5731, 5750], 'extracellular': [3, 33, 178, 208, 371, 375, 534, 796, 1182, 1715, 1743, 1957, 2290, 2455, 2459, 2618, 2880, 3267, 3733, 3761, 3975, 4308, 4819, 5192, 5220, 5434], 'calcium': [4, 179, 1744, 3762, 5221], 'concentration': [5, 180, 377, 2210, 2263, 2461, 4228, 4281], 'is': [6, 52, 125, 181, 227, 300, 351, 364, 378, 440, 449, 457, 473, 481, 536, 643, 722, 798, 835, 1134, 1407, 1527, 1568, 1627, 1735, 1780, 1994, 2031, 2062, 2106, 2380, 2435, 2448, 2462, 2524, 2533, 2541, 2557, 2565, 2620, 2727, 2806, 2882, 2920, 3219, 3492, 3545, 3586, 3645, 3753, 3798, 4012, 4049, 4080, 4124, 4398, 4471, 4771, 5045, 5099, 5140, 5212, 5257, 5471, 5508, 5539, 5583, 5654], 'maintained': [7, 182], 'within': [8, 183, 1273, 1737, 3358, 3755, 4910, 5214], 'a': [9, 39, 184, 214, 474, 491, 687, 723, 752, 903, 911, 936, 943, 965, 991, 1019, 1042, 1135, 1142, 1328, 1469, 1837, 1869, 1878, 1904, 2032, 2070, 2121, 2142, 2208, 2303, 2558, 2575, 2771, 2807, 2836, 2988, 2996, 3021, 3028, 3050, 3076, 3104, 3127, 3220, 3227, 3413, 3855, 3887, 3896, 3922, 4050, 4088, 4139, 4160, 4226, 4321, 4539, 4547, 4572, 4579, 4601, 4627, 4655, 4679, 4772, 4779, 4965, 5314, 5346, 5355, 5381, 5509, 5547, 5598], 'narrow': [10, 185], 'range': [11, 186, 1470, 1739, 2072, 3757, 4090, 5216, 5549], 'despite': [12, 187], 'large': [13, 188, 966, 3051, 4602], 'variations': [14, 189], 'in': [15, 42, 54, 128, 143, 154, 190, 217, 229, 303, 318, 329, 356, 366, 369, 451, 490, 506, 595, 637, 647, 838, 879, 901, 1186, 1348, 1359, 1367, 1370, 1374, 1381, 1393, 1417, 1423, 1456, 1524, 1534, 1596, 1617, 1642, 1666, 1693, 1748, 1759, 1789, 1973, 2041, 2110, 2137, 2154, 2191, 2268, 2276, 2289, 2407, 2440, 2450, 2453, 2535, 2574, 2590, 2679, 2721, 2731, 2923, 2964, 2986, 3271, 3433, 3444, 3452, 3455, 3459, 3466, 3478, 3502, 3508, 3542, 3552, 3614, 3635, 3660, 3684, 3711, 3766, 3777, 3807, 3991, 4059, 4128, 4155, 4172, 4209, 4286, 4294, 4307, 4425, 4474, 4515, 4537, 4823, 4986, 4997, 5005, 5008, 5012, 5019, 5031, 5055, 5061, 5096, 5106, 5170, 5225, 5236, 5266, 5450, 5518, 5587, 5681, 5718], 'daily': [16, 191], 'dietary': [17, 192, 438, 2522], 'input': [18, 193], 'and': [19, 25, 64, 99, 135, 194, 200, 239, 274, 310, 434, 463, 493, 514, 593, 693, 742, 756, 785, 825, 848, 857, 979, 1001, 1010, 1018, 1030, 1051, 1114, 1139, 1233, 1270, 1274, 1323, 1352, 1372, 1376, 1383, 1401, 1419, 1421, 1432, 1460, 1503, 1552, 1573, 1610, 1622, 1636, 1651, 1673, 1711, 1720, 1753, 1774, 1819, 1885, 1892, 1949, 2006, 2024, 2157, 2179, 2185, 2196, 2236, 2261, 2273, 2291, 2296, 2518, 2547, 2577, 2598, 2677, 2777, 2826, 2840, 2869, 2910, 2933, 2942, 3064, 3086, 3095, 3103, 3115, 3136, 3199, 3224, 3318, 3355, 3359, 3408, 3437, 3457, 3461, 3468, 3486, 3504, 3506, 3517, 3570, 3591, 3628, 3640, 3654, 3669, 3691, 3729, 3738, 3771, 3792, 3837, 3903, 3910, 3967, 4024, 4042, 4175, 4197, 4203, 4214, 4254, 4279, 4291, 4309, 4314, 4461, 4484, 4493, 4615, 4637, 4646, 4654, 4666, 4688, 4751, 4776, 4870, 4907, 4911, 4960, 4990, 5010, 5014, 5021, 5039, 5057, 5059, 5070, 5124, 5145, 5188, 5197, 5230, 5251, 5296, 5362, 5369, 5426, 5483, 5501, 5734, 5743], 'body': [20, 195, 642, 2726], 'demand.': [21, 196], 'The': [22, 197, 374, 633, 923, 1131, 1584, 1640, 1921, 2364, 2394, 2420, 2458, 2717, 3008, 3216, 3602, 3658, 3939, 4382, 4412, 4438, 4559, 4768, 5156, 5398, 5638, 5668, 5694], 'small': [23, 56, 198, 231, 783, 840, 1349, 1457, 2867, 2925, 3434, 4476, 4987], 'intestine': [24, 199, 1361, 1418, 3446, 3503, 4999, 5056], 'kidney': [26, 201, 1382, 1424, 1525, 2201, 2278, 3467, 3509, 3543, 4219, 4296, 5020, 5062, 5097, 5721], 'constitute': [27, 202], 'influx': [29, 204, 792, 832, 899, 1758, 1881, 1964, 2052, 2105, 2123, 2876, 2917, 2984, 3776, 3899, 3982, 4070, 4123, 4141, 4468, 4535, 5235, 5358, 5441, 5529, 5582, 5600], 'pathways': [30, 205, 793, 2877], 'into': [31, 206, 782, 794, 1184, 2866, 2878, 3269, 4821], 'Ca2+': [34, 43, 69, 173, 209, 218, 244, 348, 376, 404, 428, 505, 512, 521, 535, 638, 720, 780, 831, 889, 1183, 1192, 1576, 1716, 1728, 1791, 1816, 1907, 1999, 2016, 2038, 2051, 2067, 2104, 2112, 2133, 2245, 2287, 2304, 2385, 2460, 2488, 2512, 2589, 2596, 2605, 2619, 2722, 2804, 2864, 2916, 2974, 3268, 3277, 3594, 3734, 3746, 3809, 3834, 3925, 4017, 4034, 4056, 4069, 4085, 4122, 4130, 4151, 4263, 4305, 4322, 4403, 4467, 4525, 4820, 4829, 5148, 5193, 5205, 5268, 5293, 5384, 5476, 5493, 5515, 5528, 5544, 5581, 5589, 5610, 5659], 'pool': [35, 210], 'and,': [36, 211], 'therefore,': [37, 212, 1653, 3671], 'play': [38, 213], 'primary': [40, 215], 'role': [41, 216], 'homeostasis.': [44, 219], 'We': [45, 220, 1356, 3441, 4994, 5708], 'identified': [46, 221], 'an': [47, 82, 222, 257, 927, 988, 1002, 1014, 1724, 3012, 3073, 3087, 3099, 3742, 4563, 4624, 4638, 4650, 5201], 'apical': [48, 130, 223, 305, 732, 830, 881, 1532, 1631, 2056, 2103, 2257, 2292, 2816, 2915, 2966, 3550, 3649, 4074, 4121, 4275, 4310, 4466, 4517, 5104, 5533, 5580], 'Ca2+influx': [49, 147, 224, 322], 'channel,': [50, 225, 833, 2918, 4469], 'which': [51, 226, 446, 533, 788, 834, 1785, 1830, 2530, 2617, 2872, 2919, 3803, 3848, 4470, 5262, 5307], 'expressed': [53, 228, 836, 2921, 4472], 'proximal': [55, 230, 839, 1670, 2924, 3688, 4475], 'intestine,': [57, 232, 841, 1350, 1458, 2926, 3435, 4477, 4988], 'distal': [59, 155, 234, 330, 843, 920, 1493, 1541, 1547, 1618, 2060, 2928, 3005, 3559, 3565, 3636, 4078, 4479, 4556, 5113, 5119, 5537], 'part': [60, 235, 844, 1542, 1564, 2929, 3560, 3582, 4480, 5114, 5136], 'of': [61, 72, 132, 168, 236, 247, 307, 343, 445, 468, 477, 487, 520, 546, 635, 640, 727, 828, 845, 883, 918, 931, 938, 948, 970, 1013, 1045, 1144, 1170, 1181, 1190, 1236, 1339, 1345, 1410, 1415, 1466, 1471, 1484, 1537, 1543, 1565, 1571, 1594, 1615, 1633, 1661, 1664, 1677, 1691, 1729, 1740, 1764, 1955, 1984, 2009, 2015, 2035, 2058, 2073, 2120, 2131, 2144, 2166, 2176, 2188, 2211, 2265, 2294, 2306, 2310, 2319, 2332, 2342, 2352, 2375, 2384, 2404, 2417, 2423, 2529, 2552, 2561, 2571, 2604, 2630, 2719, 2724, 2811, 2913, 2930, 2968, 3003, 3016, 3023, 3033, 3055, 3098, 3130, 3229, 3255, 3266, 3275, 3321, 3424, 3430, 3495, 3500, 3555, 3561, 3583, 3589, 3612, 3633, 3651, 3679, 3682, 3695, 3709, 3747, 3758, 3782, 3973, 4002, 4027, 4033, 4053, 4076, 4091, 4138, 4149, 4162, 4184, 4194, 4206, 4229, 4283, 4312, 4324, 4328, 4337, 4350, 4360, 4370, 4393, 4402, 4422, 4435, 4441, 4464, 4481, 4519, 4554, 4567, 4574, 4584, 4606, 4649, 4682, 4781, 4807, 4818, 4827, 4873, 4977, 4983, 5048, 5053, 5109, 5115, 5137, 5143, 5168, 5206, 5217, 5241, 5432, 5461, 5486, 5492, 5512, 5535, 5550, 5597, 5608, 5616, 5626, 5649, 5658, 5678, 5691, 5697, 5714, 5727, 5749], 'nephron': [63, 238, 1545, 1567, 3563, 3585, 5117, 5139], 'placenta.': [65, 240, 849, 1461, 2934, 4485], 'This': [66, 241, 455, 496, 1563, 1734, 2539, 2580, 3581, 3752, 5135, 5211], 'novel': [67, 242, 887, 2972, 4523], 'epithelial': [68, 243, 403, 427, 859, 888, 2487, 2511, 2944, 2973, 4495, 4524], 'channel': [70, 245, 861, 890, 1138, 1817, 2946, 2975, 3223, 3835, 4497, 4526, 4775, 5294], '(ECaC)': [71, 246], '730': [73, 248, 939, 3024, 4575], 'amino': [74, 249, 940, 972, 1263, 3025, 3057, 3348, 4576, 4608, 4900], 'acids': [75, 250, 941, 973, 3026, 3058, 4577, 4609], 'contains': [76, 251, 926, 961, 3011, 3046, 4562, 4597], 'six': [77, 252, 992, 3077, 4628], 'putative': [78, 253], 'membrane-spanning': [79, 254], 'domains': [80, 255], 'with': [81, 106, 119, 137, 148, 256, 281, 294, 312, 323, 942, 995, 1226, 1321, 1387, 1413, 1474, 1481, 1559, 1605, 1638, 1713, 1723, 1810, 1821, 2045, 2349, 2430, 3027, 3080, 3311, 3406, 3472, 3498, 3577, 3623, 3656, 3731, 3741, 3828, 3839, 4063, 4367, 4448, 4578, 4631, 4863, 4958, 5025, 5051, 5131, 5190, 5200, 5287, 5298, 5522, 5623, 5704, 5730], 'additional': [83, 258, 1003, 3088, 4639], 'hydrophobic': [84, 259, 1004, 3089, 4640], 'stretch': [85, 260, 1005, 3090, 4641], 'predicted': [86, 110, 261, 285, 944, 1230, 1283, 3029, 3315, 3368, 4580, 4867, 4920], 'to': [87, 108, 151, 262, 283, 326, 509, 523, 852, 1177, 1188, 1228, 1276, 1288, 1629, 1829, 1841, 1959, 1971, 2013, 2065, 2219, 2230, 2255, 2382, 2426, 2593, 2607, 2937, 3262, 3273, 3313, 3361, 3373, 3647, 3847, 3859, 3977, 3989, 4031, 4083, 4237, 4248, 4273, 4400, 4444, 4488, 4814, 4825, 4865, 4913, 4925, 5306, 5318, 5436, 5448, 5490, 5542, 5656, 5700], 'be': [88, 263, 524, 1980, 2414, 2608, 3998, 4432, 5457, 5688], 'pore': [90, 265, 1016, 3101, 4652], 'region.': [91, 266], 'ECaC': [92, 124, 141, 159, 267, 299, 316, 334, 924, 960, 1050, 1225, 1315, 1340, 1362, 1378, 1391, 1411, 1476, 1526, 1595, 1616, 1647, 1665, 1692, 1831, 1891, 1993, 2010, 2140, 2194, 2271, 2408, 2424, 3009, 3045, 3135, 3310, 3400, 3425, 3447, 3463, 3476, 3496, 3544, 3613, 3634, 3665, 3683, 3710, 3849, 3909, 4011, 4028, 4158, 4212, 4289, 4426, 4442, 4560, 4596, 4687, 4862, 4952, 4978, 5000, 5016, 5029, 5049, 5098, 5169, 5308, 5368, 5470, 5487, 5682, 5698], 'resembles': [93, 268], 'recently': [95, 270, 854, 1053, 2939, 3138, 4490, 4690], 'cloned': [96, 271, 855, 1054, 2940, 3139, 4491, 4691], 'capsaicin': [97, 272, 1055, 1132, 3140, 3217, 4692, 4769], 'receptor': [98, 102, 273, 277, 408, 432, 549, 597, 1056, 1081, 1133, 2492, 2516, 2633, 2681, 3141, 3166, 3218, 4693, 4718, 4770], 'transient': [101, 276, 407, 431, 1080, 2491, 2515, 3165, 4717], 'potential-related': [103, 278], 'ion': [104, 279, 1015, 1084, 1290, 3100, 3169, 3375, 4651, 4721, 4927], 'channels': [105, 280, 1085, 1116, 1792, 3170, 3201, 3810, 4722, 4753, 5269], 'respect': [107, 282, 1227, 3312, 4864], 'its': [109, 284, 691, 2410, 2775, 4428, 5684], 'topology': [111, 286], 'but': [112, 287, 360, 2444], 'shares': [113, 288, 1316, 3401, 4953], 'less': [114, 289, 361, 441, 1046, 2307, 2445, 2525, 3131, 4325, 4683], 'than': [115, 290, 362, 442, 1047, 2308, 2446, 2526, 3132, 4326, 4684], '30%': [116, 291, 448, 1048, 2532, 3133, 4685], 'sequence': [117, 292, 1265, 1319, 3350, 3404, 4902, 4956, 5732], 'homology': [118, 293, 1044, 3129, 4681], 'these': [120, 295, 1312, 1333, 1989, 2251, 2428, 3397, 3418, 4007, 4269, 4446, 4949, 4970, 5466, 5702], 'channels.': [121, 296, 2000, 4018, 4971, 5477], 'kidney,': [123, 298, 1351, 1459, 1492, 3436, 4989], 'abundantly': [126, 301, 1528, 3546, 5100], 'present': [127, 302, 365, 878, 1529, 2421, 2449, 2963, 3547, 4439, 4514, 5101, 5695], 'membrane': [131, 306, 749, 882, 1533, 2057, 2833, 2967, 3551, 4075, 4518, 5105, 5534], 'Ca2+transporting': [133, 308], 'cells': [134, 309, 1185, 1538, 1641, 2061, 2202, 2250, 2279, 3270, 3556, 3659, 4079, 4220, 4268, 4297, 4822, 5110, 5538], 'colocalizes': [136, 311, 1558, 1637, 3576, 3655, 5130], '1,25-dihydroxyvitamin': [138, 169, 313, 344, 393, 417, 435, 2477, 2501, 2519], 'D3-dependent': [139, 170, 314, 345], 'calbindin-D28K.': [140, 315, 1639, 3657], 'expression': [142, 317, 820, 1364, 1380, 1409, 1455, 1690, 2905, 3449, 3465, 3494, 3708, 4456, 5002, 5018, 5047, 5167], 'Xenopus': [144, 319, 1694, 3712, 5171], 'oocytes': [145, 320, 902, 1695, 1874, 2138, 2192, 2269, 2295, 2301, 2987, 3713, 3892, 4156, 4210, 4287, 4313, 4319, 4538, 5172, 5351], 'confers': [146, 321], 'properties': [149, 163, 324, 338, 2008, 4026, 5485], 'identical': [150, 325, 2012, 4030, 5489], 'those': [152, 327, 2014, 4032, 5491], 'observed': [153, 328, 1697, 3715, 5174], 'renal': [156, 331, 688, 786, 2042, 2059, 2249, 2772, 2870, 4060, 4077, 4267, 5519, 5536], 'cells.': [157, 332, 922, 1657, 2043, 3007, 3675, 4061, 4558, 5520], 'Thus,': [158, 333], 'has': [160, 335, 522, 1832, 2606, 3850, 5309], 'expected': [162, 337], 'for': [164, 339, 651, 779, 896, 1704, 1727, 1890, 2735, 2863, 2981, 3722, 3745, 3908, 4532, 5181, 5204, 5367, 5746], 'being': [165, 340], 'gatekeeper': [167, 342], 'active': [171, 346, 743, 2827], 'transepithelial': [172, 347, 2066, 4084, 5543], 'transport.': [174, 349, 2113, 4131, 5590, 5611], 'Calcium': [350, 1431, 2434, 3516, 5069], 'most': [353, 1654, 2437, 3672], 'abundant': [354, 2438], 'cation': [355, 1137, 2439, 3222, 4774], 'human': [358, 1504, 2442], 'body,': [359, 2443], '1%': [363, 2447], 'ionic': [367, 2451], 'form': [368, 2452], 'compartment': [372, 2258, 2456, 4276], '(1).': [373, 2457], 'precisely': [379, 2463], 'controlled': [380, 2464], 'by': [381, 465, 526, 532, 538, 544, 645, 737, 751, 2226, 2330, 2465, 2549, 2610, 2616, 2622, 2628, 2729, 2821, 2835, 4244, 4348], 'parathyroid': [382, 389, 413, 540, 2466, 2473, 2497, 2624], 'hormone': [383, 2467], '(PTH)': [384, 2468], '1The': [385, 2469], 'abbreviations': [386, 410, 2470, 2494], 'used': [387, 411, 2471, 2495], 'are:PTH,': [388, 412, 2472, 2496], 'hormone;': [390, 414, 2474, 2498], '1,': [391, 415, 2475, 2499], '25-(OH)2D3,': [392, 416, 2476, 2500], 'D3;': [394, 418, 2478, 2502], 'CNT,': [395, 419, 2479, 2503], 'connecting': [396, 420, 1550, 2480, 2504, 3568, 5122], 'tubule;': [397, 421, 2481, 2505], 'CCD,': [398, 422, 2482, 2506], 'cortical': [399, 423, 1553, 1623, 2483, 2507, 3571, 3641, 5125], 'collecting': [400, 424, 1554, 1624, 1644, 2484, 2508, 3572, 3642, 3662, 5126], 'duct;': [401, 425, 2485, 2509], 'ECaC,': [402, 426, 1268, 2126, 2486, 2510, 3353, 4144, 4905, 5603], 'channel;': [405, 429, 2489, 2513], 'TRP,': [406, 430, 2490, 2514], 'potential.1The': [409, 2493], 'potential.': [433, 2517], 'D3(1,25-(OH)2D3).': [436, 2520], 'Daily': [437, 2521], 'intake': [439, 2523], '1000': [443, 2527], 'mg': [444, 504, 2528, 2588], 'only': [447, 1041, 1317, 2531, 3126, 3402, 4678, 4954], 'absorbed': [450, 2534], 'intestinal': [453, 511, 784, 2537, 2595, 2868], 'tract.': [454, 2538], 'percentage': [456, 2540], 'significantly': [458, 1962, 2542, 3980, 5439], 'enhanced': [459, 2543], 'during': [460, 2544], 'growth,': [461, 2545], 'pregnancy,': [462, 2546], 'lactation': [464, 2548], 'increased': [466, 1712, 1906, 2550, 3730, 3924, 5189, 5383], 'levels': [467, 2551], 'circulating': [469, 2553], '1,25-(OH)2D3.': [470, 2554], 'Although': [471, 2555], 'there': [472, 480, 2556, 2564], 'continuous': [475, 2559], 'turnover': [476, 2560], 'bone': [478, 489, 2562, 2573], 'mass,': [479, 2563], 'no': [482, 1777, 2566, 3795, 5254], 'net': [483, 2567], 'gain': [484, 2568], 'or': [485, 2409, 2569, 4427, 5683], 'loss': [486, 2570], 'Ca2+from': [488, 2572], 'young': [492, 2576], 'healthy': [494, 499, 2578, 2583], 'individual.': [495, 2579], 'implicates': [497, 2116, 2581, 4134, 5593], 'that': [498, 515, 934, 959, 1285, 1358, 1408, 1414, 1523, 1698, 1782, 1953, 1992, 2028, 2049, 2101, 2117, 2582, 2599, 3019, 3044, 3370, 3443, 3493, 3499, 3541, 3716, 3800, 3971, 4010, 4046, 4067, 4119, 4135, 4570, 4595, 4922, 4996, 5046, 5052, 5095, 5175, 5259, 5430, 5469, 5505, 5526, 5578, 5594], 'adults': [500, 2584], 'excrete': [501, 2585], 'maximally': [502, 2586], '300': [503, 2587], 'urine': [508, 2592], 'balance': [510, 2594], 'uptake': [513, 1701, 2136, 2190, 2267, 2305, 2597, 3719, 4154, 4208, 4285, 4323, 5178], 'remaining': [517, 2601], 'filtered': [518, 2602], 'load': [519, 2603], 'reabsorbed': [525, 2609], 'kidney.': [528, 1598, 2612, 3616], 'Recently,': [529, 2613], 'mechanism': [531, 777, 2615, 2861], 'sensed': [537, 2621], 'gland': [541, 2625], 'was': [542, 891, 908, 1260, 1365, 1385, 1702, 2215, 2224, 2328, 2626, 2976, 2993, 3345, 3450, 3470, 3720, 4233, 4242, 4346, 4527, 4544, 4897, 5003, 5023, 5179], 'elucidated': [543, 2627], 'cloning': [545, 2629], 'Ca2+-sensing': [548, 2632], '(1van': [550, 2634], 'Os': [551, 2085, 2635, 4103, 5562], 'C.H.': [552, 2086, 2636, 4104, 5563], 'Biochim.': [553, 2637], 'Biophys.': [554, 2638], 'Acta.': [555, 2639], '1987;': [556, 2640], '906:': [557, 2641], '195-222Crossref': [558, 2642], 'PubMed': [559, 588, 628, 682, 714, 768, 810, 873, 1074, 1109, 1128, 1164, 1217, 1254, 1863, 1944, 2094, 2643, 2672, 2712, 2766, 2798, 2852, 2894, 2958, 3159, 3194, 3213, 3249, 3302, 3339, 3881, 3962, 4112, 4509, 4711, 4746, 4765, 4801, 4854, 4891, 5340, 5421, 5571], 'Scopus': [560, 589, 629, 683, 715, 769, 811, 874, 1075, 1110, 1165, 1218, 1255, 1307, 1803, 1864, 1945, 2095, 2644, 2673, 2713, 2767, 2799, 2853, 2895, 2959, 3160, 3195, 3250, 3303, 3340, 3392, 3821, 3882, 3963, 4113, 4510, 4712, 4747, 4802, 4855, 4892, 4944, 5280, 5341, 5422, 5572], '(114)': [561, 2645], 'Google': [562, 591, 631, 685, 717, 771, 813, 876, 1077, 1112, 1129, 1167, 1220, 1257, 1309, 1452, 1805, 1866, 1947, 2097, 2646, 2675, 2715, 2769, 2801, 2855, 2897, 2961, 3162, 3197, 3214, 3252, 3305, 3342, 3394, 3537, 3823, 3884, 3965, 4115, 4512, 4714, 4749, 4766, 4804, 4857, 4894, 4946, 5090, 5282, 5343, 5424, 5574], 'Scholar,': [563, 1441, 1929, 2647, 3526, 3947, 5079, 5406], '2Brown': [564, 2648], 'E.M.': [565, 606, 2649, 2690], 'Gamba': [566, 2650], 'G.': [567, 1093, 1201, 2077, 2651, 3178, 3286, 4095, 4730, 4838, 5554], 'Riccardi': [568, 2652], 'D.': [569, 707, 1069, 1159, 1581, 1858, 1918, 2653, 2791, 3154, 3244, 3599, 3876, 3936, 4706, 4796, 5153, 5335, 5395], 'Lombarbi': [570, 2654], 'M.': [571, 664, 1063, 1089, 1091, 1153, 1197, 1199, 1443, 1852, 2655, 2748, 3148, 3174, 3176, 3238, 3282, 3284, 3528, 3870, 4700, 4726, 4728, 4790, 4834, 4836, 5081, 5329], 'Butters': [572, 2656], 'R.': [573, 1095, 1203, 1445, 2083, 2657, 3180, 3288, 3530, 4101, 4732, 4840, 5083, 5560], 'Kifor': [574, 2658], 'O.': [575, 2659], 'Sun': [576, 2660], 'A.': [577, 658, 2661, 2742], 'Hediger': [578, 2662], 'M.A.': [579, 1061, 1151, 1850, 2663, 3146, 3236, 3868, 4698, 4788, 5327], 'Lytton': [580, 2664, 5717], 'J.': [581, 670, 677, 1123, 1447, 1797, 2665, 2754, 2761, 3208, 3532, 3815, 4760, 5085, 5274], 'Hebert': [582, 609, 2666, 2693], 'S.C.': [583, 610, 2667, 2694], 'Nature.': [584, 869, 1070, 1160, 1859, 2668, 2954, 3155, 3245, 3877, 4505, 4707, 4797, 5336], '1993;': [585, 622, 870, 1301, 2669, 2706, 2955, 3386, 4506, 4938], '366:': [586, 2670], '575-580Crossref': [587, 2671], '(2344)': [590, 2674], 'Scholar),': [592, 686, 877, 1078, 1806, 1948, 2098, 2676, 2770, 2962, 3163, 3824, 3966, 4116, 4513, 4715, 5283, 5425, 5575], 'mutations': [594, 646, 2406, 2678, 2730, 4424, 5680], 'this': [596, 886, 1976, 2099, 2115, 2680, 2971, 3994, 4117, 4133, 4522, 5453, 5576, 5592], 'gene': [598, 2682], 'explained': [599, 2683], 'familial': [600, 2684], 'hypocalciuric': [601, 2685], 'hypercalcemia': [602, 2686], '(3Pollak': [603, 2687], 'M.R.': [604, 697, 2688, 2781], 'Brown': [605, 2689], 'Chou': [607, 2691], 'Y.H.': [608, 2692], 'Marx': [611, 2695], 'S.J.': [612, 2696], 'Steinmann': [613, 2697], 'B.': [614, 1298, 1588, 1925, 2368, 2398, 2698, 3383, 3606, 3943, 4386, 4416, 4935, 5160, 5402, 5642, 5672], 'Levi': [615, 2699], 'T.': [616, 660, 672, 2700, 2744, 2756], 'Seidman': [617, 619, 2701, 2703], 'C.E.': [618, 2702], 'J.G.': [620, 2704], 'Cell.': [621, 1100, 1208, 2705, 3185, 3293, 4737, 4845], '75:': [623, 766, 808, 2707, 2850, 2892], '1237-1239Abstract': [624, 2708], 'Full': [625, 1104, 1106, 1212, 1214, 1251, 1304, 1941, 2709, 3189, 3191, 3297, 3299, 3336, 3389, 3959, 4741, 4743, 4849, 4851, 4888, 4941, 5418], 'Text': [626, 1105, 1107, 1213, 1215, 1252, 1305, 1942, 2710, 3190, 3192, 3298, 3300, 3337, 3390, 3960, 4742, 4744, 4850, 4852, 4889, 4942, 5419], 'PDF': [627, 1108, 1216, 1253, 1306, 1943, 2711, 3193, 3301, 3338, 3391, 3961, 4745, 4853, 4890, 4943, 5420], '(897)': [630, 2714], 'Scholar).': [632, 718, 772, 1130, 1168, 1221, 1258, 1310, 1867, 2372, 2402, 2716, 2802, 2856, 2898, 3215, 3253, 3306, 3343, 3395, 3885, 4390, 4420, 4767, 4805, 4858, 4895, 4947, 5091, 5164, 5344, 5646, 5676], 'importance': [634, 2718], '1,25-(OH)2D3': [636, 2720], 'homeostasis': [639, 2723], 'reflected': [644, 2728], 'genes': [649, 2733], 'coding': [650, 2734], '1α-hydroxylase': [652, 2736], '(4Kitanaka': [653, 2737], 'S.': [654, 674, 1794, 2738, 2758, 3812, 5271], 'Takeyama': [655, 2739], 'K.': [656, 662, 2740, 2746], 'Murayama': [657, 2741], 'Sato': [659, 2743], 'Okumura': [661, 2745], 'Nogami': [663, 2747], 'Hasegawa': [665, 2749], 'Y.': [666, 2750], 'Niimi': [667, 2751], 'H.': [668, 1796, 2752, 3814, 5273], 'Yanagisawa': [669, 2753], 'Tanaka': [671, 2755], 'Kato': [673, 2757], 'N.': [675, 2759], 'Engl.': [676, 2760], 'Med.': [678, 2762], '1998;': [679, 2763], '338:': [680, 2764], '653-661Crossref': [681, 2765], '(289)': [684, 2768], 'enzyme': [689, 2773], 'controlling': [690, 2774], 'synthesis,': [692, 2776], '1,25-(OH)2D3-receptor': [695, 2779], '(5Hughes': [696, 2780], 'Malloy': [698, 2782], 'P.J.': [699, 2783], 'Kieback': [700, 2784], 'D.G.': [701, 2785], 'Kesterson': [702, 2786], 'R.A.': [703, 2787], 'Pike': [704, 2788], 'J.W.': [705, 2789], 'Feldman': [706, 2790], "O'Malley": [708, 2792], 'B.W.': [709, 2793], 'Science.': [710, 2794], '1988;': [711, 2795], '242:': [712, 2796], '1702-1705Crossref': [713, 2797], '(418)': [716, 2800], 'Transepithelial': [719, 2803], 'transport': [721, 2017, 2039, 2074, 2198, 2246, 2275, 2805, 4035, 4057, 4092, 4216, 4264, 4293, 5494, 5516, 5551], 'three-step': [724, 2808], 'process': [725, 2809], 'consisting': [726, 2810], 'passive': [728, 2812], 'entry': [729, 781, 1180, 2813, 2865, 3265, 4817], 'across': [730, 745, 2018, 2199, 2248, 2814, 2829, 4036, 4217, 4266, 5495], 'membrane,': [733, 2233, 2817, 4251], 'cytosolic': [734, 2818], 'diffusion': [735, 2819], 'facilitated': [736, 2820], '1,25-(OH)2D3-dependent': [738, 2822], 'calcium-binding': [739, 2823], 'proteins': [740, 1223, 1272, 2824, 3308, 3357, 4860, 4909], '(calbindins),': [741, 2825], 'extrusion': [744, 2828], 'opposing': [747, 2831], 'basolateral': [748, 2832], 'mediated': [750, 2834], 'high': [753, 2837], 'affinity': [754, 1726, 2838, 3744, 5203], 'Ca2+-ATPase': [755, 2839], 'Na+-Ca2+': [757, 2841], 'exchanger': [758, 2842], '(6Friedman': [759, 801, 2843, 2885], 'P.A.': [760, 802, 2844, 2886], 'Gesek': [761, 803, 2845, 2887], 'F.': [762, 804, 2081, 2846, 2888, 4099, 5558], 'Physiol.': [763, 805, 1448, 1798, 2847, 2889, 3533, 3816, 5086, 5275], 'Rev.': [764, 806, 2848, 2890], '1995;': [765, 807, 2849, 2891], '429-471Crossref': [767, 809, 2851, 2893], '(196)': [770, 812, 2854, 2896], 'Until': [773, 2857], 'now,': [774, 2858], 'molecular': [776, 946, 1982, 2431, 2860, 3031, 4000, 4449, 4582, 5459, 5705], 'responsible': [778, 2862], 'cells,': [787, 2871], 'serve': [789, 2873], 'as': [790, 1141, 1845, 2141, 2874, 3226, 3863, 4159, 4778, 5322], 'Ca2+pool,': [797, 2881], 'still': [799, 2883], 'elusive': [800, 2884], 'Scholar).RESULTS': [814], 'AND': [815, 2900], 'DISCUSSIONHere,': [816, 2901], 'we': [817, 1696, 1951, 2902, 3714, 3969, 4453, 5173, 5428], 'report': [818, 2903, 4454], 'cloning,': [821, 2906, 4457], 'tissue': [822, 2907, 4458], 'distribution,': [823, 2908, 4459], 'immunolocalization,': [824, 2909, 4460], 'functional': [826, 1689, 2007, 2911, 3707, 4025, 4462, 5166, 5484], 'characterization': [827, 2175, 2912, 4193, 4463], 'solely': [837, 2922, 4473], 'nephron,': [847, 2932, 4483], 'analogy': [851, 2936, 4487], 'amiloride-sensitive': [856, 2941, 4492], 'aldosterone-dependent': [858, 2943, 4494], 'Na+': [860, 1846, 1880, 2945, 3864, 3898, 4496, 5323, 5357], '(ENaC)': [862, 2947, 4498], '(10Canessa': [863, 2948, 4499], 'C.M.': [864, 2949, 4500], 'Horisberger': [865, 2950, 4501], 'J.D.': [866, 1067, 1157, 1856, 2951, 3152, 3242, 3874, 4502, 4704, 4794, 5333], 'Rossier': [867, 2952, 4503], 'B.C.': [868, 2953, 4504], '361:': [871, 2956, 4507], '467-470Crossref': [872, 2957, 4508], '(822)': [875, 2960, 4511], 'sodium-transporting': [884, 2969, 4520], 'epithelia,': [885, 2970, 4521], 'named': [892, 2977, 4528], 'ECaC.': [893, 1811, 2177, 2978, 3829, 4195, 4529, 5288], 'By': [894, 2979, 4530, 5165], 'screening': [895, 2980, 4531], 'maximal': [897, 2982, 4533], '45Ca2+': [898, 1700, 1757, 2189, 2266, 2983, 3718, 3775, 4207, 4284, 4534, 5177, 5234], 'activity': [900, 2985, 4536], 'single': [904, 2122, 2989, 4140, 4540, 5599], '2.8-kilobase': [905, 2990, 4541], 'pair': [906, 2991, 4542], 'cDNA': [907, 913, 925, 2992, 2998, 3010, 4543, 4549, 4561, 5722], 'isolated': [909, 2994, 4545], 'from': [910, 916, 1468, 1487, 1996, 2217, 2346, 2995, 3001, 4014, 4235, 4364, 4546, 4552, 5473, 5620], 'directional': [912, 2997, 4548], 'library': [914, 2999, 4550], 'prepared': [915, 3000, 4551], 'poly(A)+RNA': [917, 3002, 4553], 'rabbit': [919, 1488, 1597, 2200, 2277, 3004, 3615, 4218, 4295, 4555], 'tubular': [921, 3006, 4557], 'open': [928, 3013, 4564], 'reading': [929, 3014, 4565, 5748], 'frame': [930, 3015, 4566], '2190': [932, 3017, 4568], 'nucleotides': [933, 3018, 4569], 'encodes': [935, 3020, 4571], 'protein': [937, 982, 1027, 1036, 2030, 3022, 3067, 3112, 3121, 4048, 4573, 4618, 4663, 4673, 5507], 'relative': [945, 1838, 3030, 3856, 4581, 5315], 'mass': [947, 1508, 3032, 4583], '83': [949, 3034, 4585], 'kDa': [950, 3035, 4586], '(M': [951, 3036, 4587], 'r': [952, 3037, 4588], '83,000)': [953, 3038, 4589], '(Fig.': [954, 1034, 1293, 1354, 1561, 1709, 1965, 2021, 3039, 3119, 3378, 3439, 3579, 3727, 3983, 4039, 4590, 4670, 4930, 4992, 5133, 5186, 5442, 5498], '1A).': [955, 3040, 4591], 'Hydropathy': [956, 3041, 4592], 'analysis': [957, 1338, 1465, 2331, 3042, 3423, 4349, 4593, 4976], 'suggests': [958, 2100, 3043, 4118, 4594, 5577], 'three': [962, 975, 2167, 3047, 3060, 4185, 4598, 4611], 'structural': [963, 3048, 4599], 'domains:': [964, 3049, 4600], 'hydrophilic': [967, 1020, 3052, 3105, 4603, 4656], 'amino-terminal': [968, 3053, 4604], 'domain': [969, 994, 3054, 3079, 4605, 4630], '327': [971, 3056, 4607], 'containing': [974, 1025, 3059, 3110, 4610, 4661], 'ankyrin': [976, 1239, 3061, 3324, 4612, 4876], 'binding': [977, 3062, 4613], 'repeats': [978, 1240, 3063, 3325, 4614, 4877], 'several': [980, 3065, 4616], 'potential': [981, 997, 1026, 1082, 3066, 3082, 3111, 3167, 4617, 4633, 4662, 4719], 'kinase': [983, 1028, 3068, 3113, 4619, 4664], 'C': [984, 1031, 2023, 2260, 3069, 3116, 4041, 4278, 4620, 4667, 5500], 'phosphorylation': [985, 1032, 3070, 3117, 4621, 4668], 'sites,': [986, 3071, 4622], 'suggesting': [987, 1327, 3072, 3412, 4623, 4964], 'intracellular': [989, 1191, 3074, 3276, 4625, 4828], 'location;': [990, 3075, 4626], 'transmembrane-spanning': [993, 3078, 4629], 'two': [996, 3081, 4632], 'N-linked': [998, 3083, 4634], 'glycosylation': [999, 3084, 4635], 'sites': [1000, 1033, 3085, 3118, 4636, 4669], 'between': [1006, 1049, 1267, 1718, 3091, 3134, 3352, 3736, 4642, 4686, 4904, 5195], 'transmembrane': [1007, 1279, 3092, 3364, 4643, 4916], 'segments': [1008, 3093, 4644], '5': [1009, 1750, 3094, 3768, 4645, 5227], '6': [1011, 3096, 4647], 'indicative': [1012, 3097, 4648], 'region;': [1017, 3102, 4653], '151-amino': [1021, 3106, 4657], 'acid': [1022, 1264, 3107, 3349, 4658, 4901], 'carboxyl': [1023, 3108, 4659], 'terminus': [1024, 3109, 4660], 'A': [1029, 1967, 2178, 3114, 3985, 4196, 4665, 4672, 5444], '1B).A': [1035, 3120], 'data': [1037, 3122, 4674], 'base': [1038, 3123, 4675], 'search': [1039, 3124, 4676], 'revealed': [1040, 1342, 1522, 3125, 3427, 3540, 4677, 4980, 5094], 'significant': [1043, 1879, 3128, 3897, 4680, 5356], '(VR1)': [1057, 3142, 4694], '(11Caterina': [1058, 1148, 1847, 3143, 3233, 3865, 4695, 4785, 5324], 'M.J.': [1059, 1149, 1848, 2359, 2389, 3144, 3234, 3866, 4377, 4407, 4696, 4786, 5325, 5633, 5663], 'Schumacher': [1060, 1150, 1849, 3145, 3235, 3867, 4697, 4787, 5326], 'Tominaga': [1062, 1152, 1851, 3147, 3237, 3869, 4699, 4789, 5328], 'Rosen': [1064, 1154, 1853, 3149, 3239, 3871, 4701, 4791, 5330], 'T.A.': [1065, 1155, 1854, 3150, 3240, 3872, 4702, 4792, 5331], 'Levine': [1066, 1156, 1855, 3151, 3241, 3873, 4703, 4793, 5332], 'Julius': [1068, 1158, 1857, 3153, 3243, 3875, 4705, 4795, 5334], '1997;': [1071, 1125, 1161, 1860, 2091, 3156, 3210, 3246, 3878, 4109, 4708, 4762, 4798, 5337, 5568], '389:': [1072, 1162, 1861, 3157, 3247, 3879, 4709, 4799, 5338], '816-824Crossref': [1073, 1163, 1862, 3158, 3248, 3880, 4710, 4800, 5339], '(6938)': [1076, 1166, 1865, 3161, 3251, 3883, 4713, 4803, 5342], '(TRP)-related': [1083, 3168, 4720], '(12Zhu': [1086, 1194, 3171, 3279, 4723, 4831], 'X.': [1087, 1195, 3172, 3280, 4724, 4832], 'Jiang': [1088, 1196, 3173, 3281, 4725, 4833], 'Peyton': [1090, 1198, 3175, 3283, 4727, 4835], 'Boulay': [1092, 1200, 3177, 3285, 4729, 4837], 'Hurst': [1094, 1202, 3179, 3287, 4731, 4839], 'Stefani': [1096, 1204, 3181, 3289, 4733, 4841], 'E.': [1097, 1205, 3182, 3290, 4734, 4842], 'Birnbaumer': [1098, 1206, 3183, 3291, 4735, 4843], 'L.': [1099, 1207, 3184, 3292, 4736, 4844], '1996;': [1101, 1209, 3186, 3294, 4738, 4846], '85:': [1102, 1210, 3187, 3295, 4739, 4847], '661-671Abstract': [1103, 1211, 3188, 3296, 4740, 4848], '(596)': [1111, 1219, 3196, 3304, 4748, 4856], 'Scholar)': [1113, 3198, 4750], 'olfactory': [1115, 3200, 4752], '(13Colbert': [1117, 3202, 4754], 'H.A.': [1118, 3203, 4755], 'Smith': [1119, 3204, 4756], 'T.L.': [1120, 3205, 4757], 'Bargmann': [1121, 3206, 4758], 'C.I.': [1122, 3207, 4759], 'Neurosci.': [1124, 1300, 3209, 3385, 4761, 4937], '17:': [1126, 3211, 4763], '8259-8269Crossref': [1127, 3212, 4764], 'nonselective': [1136, 3221, 4773], 'functions': [1140, 3225, 4777], 'transducer': [1143, 3228, 4780], 'painful': [1145, 3230, 4782], 'thermal': [1146, 3231, 4783], 'stimuli': [1147, 3232, 4784], 'Members': [1169, 3254, 4806], 'TRP': [1172, 1324, 3257, 3409, 4809, 4961], 'family': [1173, 1325, 3258, 3410, 4810, 4962], 'have': [1174, 3259, 4811], 'been': [1175, 3260, 4812], 'proposed': [1176, 3261, 4813], 'mediate': [1178, 3263, 4815], 'response': [1187, 3272, 4824], 'depletion': [1189, 3274, 4826], 'stores': [1193, 3278, 4830], 'These': [1222, 3307, 4859], 'resemble': [1224, 3309, 4861], 'their': [1229, 3314, 4866], 'topological': [1231, 3316, 4868], 'organization': [1232, 3317, 4869], 'presence': [1235, 3320, 4872], 'multiple': [1237, 3322, 4874], 'NH2-terminal': [1238, 3323, 4875], '(14Michaely': [1241, 3326, 4878], 'P.': [1242, 3327, 4879], 'Bennet': [1243, 3328, 4880], 'V.': [1244, 3329, 4881], 'Trends': [1245, 1299, 3330, 3384, 4882, 4936], 'Cell': [1246, 1433, 2089, 3331, 3518, 4107, 4883, 5071, 5566], 'Biol.': [1247, 3332, 4884], '1992;': [1248, 3333, 4885], '2:': [1249, 3334, 4886], '127-129Abstract': [1250, 3335, 4887], '(179)': [1256, 3341, 4893], 'There': [1259, 3344, 4896], 'also': [1261, 1649, 3346, 3667, 4898], 'striking': [1262, 1781, 3347, 3799, 4899, 5258], 'similarity': [1266, 1320, 3351, 3405, 4903, 4957], 'VR1,': [1269, 1828, 3354, 3846, 4906, 5305], 'TRP-related': [1271, 3356, 4908], 'adjacent': [1275, 3360, 4912], 'sixth': [1278, 3363, 4915], 'segment,': [1280, 3365, 4917], 'including': [1281, 1546, 3366, 3564, 4918, 5118], 'area': [1284, 3369, 4921], 'may': [1286, 2127, 2412, 3371, 4145, 4430, 4923, 5604, 5686], 'contribute': [1287, 3372, 4924], 'permeation': [1291, 3376, 4928], 'path': [1292, 3377, 4929], '1C)': [1294, 3379, 4931], '(15Hardie': [1295, 3380, 4932], 'R.C.': [1296, 3381, 4933], 'Minke': [1297, 3382, 4934], '61:': [1302, 3387, 4939], '371-376Abstract': [1303, 3388, 4940], '(233)': [1308, 3393, 4945], 'Outside': [1311, 3396, 4948], 'regions,': [1313, 3398, 4950], 'however,': [1314, 3399, 4951], '20%': [1318, 3403, 4955], 'VR1': [1322, 3407, 4959], 'members,': [1326, 3411, 4963], 'distant': [1329, 3414, 4966], 'evolutionary': [1330, 3415, 4967], 'relationship': [1331, 3416, 4968], 'among': [1332, 3417, 4969], 'channels.High': [1334, 3419], 'stringency': [1335, 3420, 4973], 'Northern': [1336, 1463, 3421, 4974], 'blot': [1337, 1464, 3422, 4975], 'transcripts': [1341, 1392, 3426, 3477, 4979, 5030], 'prominent': [1343, 3428, 4981], 'bands': [1344, 3429, 4982], '∼3': [1346, 3431, 4984], 'kb': [1347, 3432, 4985], 'placenta': [1353, 1384, 1420, 3438, 3469, 3505, 4991, 5022, 5058], '2).': [1355, 3440, 4993], 'found': [1357, 3442, 4995], 'mRNA': [1363, 1379, 3448, 3464, 5001, 5017], 'highest': [1366, 1834, 3451, 3852, 5004, 5311], 'duodenum,': [1368, 1489, 3453, 5006], 'decreased': [1369, 3454, 5007], 'jejunum,': [1371, 1490, 3456, 5009], 'absent': [1373, 3458, 5011], 'ileum': [1375, 3460, 5013], 'colon.': [1377, 3462, 5015], 'comparable': [1386, 3471, 5024], 'jejunum.': [1388, 3473, 5026], 'addition,': [1390, 1813, 3475, 3831, 5028, 5290], 'lung,': [1394, 1495, 3479, 5032], 'skeletal': [1395, 1496, 3480, 5033], 'muscle,': [1396, 1497, 3481, 5034], 'stomach,': [1397, 1498, 3482, 5035], 'heart,': [1398, 1499, 3483, 5036], 'liver,': [1399, 1501, 3484, 5037], 'spleen,': [1400, 1500, 3485, 5038], 'brain': [1402, 3487, 5040], 'were': [1403, 1479, 1602, 1648, 1825, 2147, 2205, 2238, 2253, 2282, 3488, 3620, 3666, 3843, 4165, 4223, 4256, 4271, 4300, 5041, 5302], 'undetectable.': [1404, 3489, 5042], 'Most': [1405, 3490, 5043], 'important': [1406, 3491, 5044], 'coincides': [1412, 3497, 5050], 'calbindin-D9K': [1416, 3501, 5054], 'calbindin-D28K': [1422, 1560, 3507, 3578, 5060, 5132], '(16Wasserman': [1425, 3510, 5063], 'R.H.': [1426, 3511, 5064], 'Fullmer': [1427, 3512, 5065], 'C.S.': [1428, 3513, 5066], 'Chung': [1429, 3514, 5067], 'W.Y.': [1430, 3515, 5068], 'Function.': [1434, 3519, 5072], 'II.': [1435, 2366, 2396, 3520, 4384, 4414, 5073, 5640, 5670], 'Academic': [1436, 3521, 5074], 'Press,': [1437, 3522, 5075], 'New': [1438, 3523, 5076], 'York1982:': [1439, 3524, 5077], '175-216Google': [1440, 3525, 5078], '17Gross': [1442, 3527, 5080], 'Kumar': [1444, 3529, 5082], 'Am.': [1446, 3531, 5084], '1990;': [1449, 3534, 5087], '259:': [1450, 3535, 5088], 'F195-F209PubMed': [1451, 3536, 5089], 'Scholar).Figure': [1453, 1592, 3610], '2ECaC': [1454], 'High-stringency': [1462], 'RNA': [1467, 1486], 'tissues': [1472], 'probed': [1473], '32P-labeled': [1475], 'cDNA.': [1477], 'Lanes': [1478], 'loaded': [1480], '2.5': [1482], 'μg': [1483], 'poly(A)+': [1485], 'ileum,': [1491], 'colon,': [1494], 'brain,': [1502], 'placenta,': [1505], 'respectively.': [1506, 2299, 4317], 'Molecular': [1507], 'standards': [1509], '(in': [1510], 'kilobases)': [1511], 'are': [1512, 1786, 2011, 2162, 2315, 3804, 4029, 4180, 4333, 5263, 5488], 'indicated': [1513, 2151, 2286, 4169, 4304], 'on': [1514], 'theleft.View': [1515], 'Large': [1516, 1684, 2169, 2334, 3702, 4187, 4352], 'Image': [1517, 1685, 2170, 2335, 3703, 4188, 4353], 'Figure': [1518, 1686, 2171, 2336, 3704, 4189, 4354], 'ViewerDownload': [1519, 1687, 2172, 2337, 3705, 4190, 4355], '(PPT)Immunofluorescence': [1520], 'staining': [1521, 1663, 3539, 3681, 5093], 'along': [1530, 3548, 5102], 'majority': [1536, 3554, 5108], 'lining': [1539, 3557, 5111], 'convoluted': [1548, 1619, 1671, 3566, 3637, 3689, 5120], 'tubule,': [1549, 3567, 5121], 'tubule': [1551, 3569, 5123], 'duct,': [1555, 3573, 5127], 'where': [1556, 3574, 5128], 'it': [1557, 3575, 5129], '3).': [1562, 3580, 5134], 'site': [1570, 3588, 5142], 'PTH-': [1572, 3590, 5144], '1,25-(OH)2D3-regulated': [1574, 3592, 5146], 'transcellular': [1575, 2037, 2111, 2132, 2244, 3593, 4055, 4129, 4150, 4262, 5147, 5514, 5588, 5609], 'reabsorption': [1577, 3595, 5149], '(18Suki': [1578, 1915, 3596, 3933, 5150, 5392], 'W.N.': [1579, 1916, 3597, 3934, 5151, 5393], 'Rouse': [1580, 1917, 3598, 3935, 5152, 5394], 'Brenner': [1582, 1919, 2362, 2392, 3600, 3937, 4380, 4410, 5154, 5396, 5636, 5666], 'B.M.': [1583, 1920, 2363, 2393, 3601, 3938, 4381, 4411, 5155, 5397, 5637, 5667], 'Kidney.': [1585, 1922, 2365, 2395, 3603, 3940, 4383, 4413, 5157, 5399, 5639, 5669], 'I.': [1586, 1923, 3604, 3941, 5158, 5400], 'W.': [1587, 1924, 2367, 2397, 3605, 3942, 4385, 4415, 5159, 5401, 5641, 5671], 'Saunders,': [1589, 1926, 2369, 2399, 3607, 3944, 4387, 4417, 5161, 5403, 5643, 5673], 'Philadelphia1996:': [1590, 1927, 2370, 2400, 3608, 3945, 4388, 4418, 5162, 5404, 5644, 5674], '472-515Google': [1591, 1928, 3609, 3946, 5163, 5405], '3Immunohistochemistry': [1593, 3611], 'Kidney': [1599, 1936, 3617, 3954, 5413], 'cortex': [1600, 3618], 'sections': [1601, 3619], 'double': [1603, 1870, 3621, 3888, 5347], 'stained': [1604, 3622], 'anti-ECaC': [1606, 3624], 'antiserum': [1607, 3625], '(A,': [1608, 3626], 'C)': [1609, 3627], 'anti-calbindin-D28K': [1611, 3629], '(B,': [1612, 3630], 'D).': [1613, 3631], 'Localization': [1614, 3632], 'tubules': [1620, 3638], '(A)': [1621, 2195, 3639, 4213], 'ducts': [1625, 3643], '(C)': [1626, 2272, 3644, 4290], 'restricted': [1628, 3646], 'region': [1632, 3650], 'cell': [1635, 3653], 'duct': [1645, 3663], 'lacking': [1646, 3664], 'calbindin-D28K-negative': [1650, 3668], 'are,': [1652, 3670], 'likely': [1655, 3673], 'intercalated': [1656, 3674], 'Note': [1658, 3676], 'absence': [1660, 3678], 'immunopositive': [1662, 3680], 'surrounding': [1668, 3686], 'glomeruli,': [1669, 3687], 'tubules,': [1672, 3690], 'thick': [1674, 3692], 'ascending': [1675, 3693], 'limb': [1676, 3694], "Henle's": [1678, 3696], 'loop.': [1679, 3697], 'Bar': [1680, 3698], 'denotes': [1681, 3699], '10': [1682, 2241, 3700, 4259], 'μm.View': [1683, 3701], '(PPT)By': [1688, 3706], 'linear': [1703, 3721, 5180], 'at': [1705, 2054, 2149, 2207, 2240, 2284, 3723, 4072, 4167, 4225, 4258, 4302, 5182, 5531], 'least': [1706, 3724, 5183], '2': [1707, 3725, 5184], 'h': [1708, 3726, 5185], '4)': [1710, 3728, 5187], 'increasing': [1714, 3732, 5191], 'concentrations': [1717, 2288, 3735, 4306, 5194], '0.01': [1719, 3737, 5196], '2.0': [1721, 3739, 5198], 'mm': [1722, 1731, 1823, 2222, 2228, 3740, 3749, 3841, 4240, 4246, 5199, 5208, 5300], 'apparent': [1725, 3743, 5202], '∼0.2': [1730, 3748, 5207], '(Fig.5': [1732, 3750, 5209], 'C).': [1733, 3751, 5210], 'well': [1736, 1979, 2413, 3754, 3997, 4431, 5213, 5456, 5687], 'physiologically': [1741, 3759, 5218], 'relevant': [1742, 3760, 5219], 'concentrations.': [1745, 3763, 5222], 'As': [1746, 3764, 5223], 'shown': [1747, 3765, 5224], 'Fig.': [1749, 3767, 5226], 'A,': [1751, 3769, 5228], 'trivalent': [1752, 3770, 5229], 'divalent': [1754, 3772, 5231], 'cations': [1755, 3773, 5232], 'inhibited': [1756, 3774, 5233], 'following': [1761, 3779, 5238], 'rank': [1762, 3780, 5239], 'order': [1763, 3781, 5240], 'potency:': [1765, 3783, 5242], 'La3+': [1766, 3784, 5243], '>': [1767, 1769, 1900, 3785, 3787, 3918, 5244, 5246, 5377], 'Cd2+': [1768, 3786, 5245], 'Mn2+,': [1770, 3788, 5247], 'while': [1771, 1902, 3789, 3920, 5248, 5379], 'Ba2+,': [1772, 3790, 5249], 'Mg2+,': [1773, 3791, 5250], 'Sr2+': [1775, 3793, 5252], 'had': [1776, 3794, 5253], 'effect.': [1778, 1827, 3796, 3845, 5255, 5304], 'It': [1779, 3797, 5256], 'Ba2+and': [1783, 3801, 5260], 'Sr2+,': [1784, 3802, 5261], 'highly': [1787, 3805, 5264], 'permeant': [1788, 3806, 5265], 'voltage-gated': [1790, 3808, 5267], '(19Hagiwara': [1793, 3811, 5270], 'Ohmori': [1795, 3813, 5272], '(Lond.).': [1799, 3817, 5276], '1982;': [1800, 3818, 5277], '331:': [1801, 3819, 5278], '231-252Crossref': [1802, 3820, 5279], '(164)': [1804, 3822, 5281], 'do': [1807, 3825, 5284], 'not': [1808, 1876, 3826, 3894, 5285, 5353], 'interfere': [1809, 3827, 5286], 'L-type': [1815, 3833, 5292], 'antagonists': [1818, 3836, 5295], 'depolarization': [1820, 3838, 5297], '50': [1822, 2221, 2227, 3840, 4239, 4245, 5299], 'KCl': [1824, 2229, 3842, 4247, 5301], 'without': [1826, 3844, 5303], 'homology,': [1835, 3853, 5312], 'shows': [1836, 3854, 5313], 'low': [1839, 3857, 5316], 'permeability': [1840, 3858, 5317], 'monovalent': [1842, 3860, 5319], 'ions': [1843, 3861, 5320], 'such': [1844, 3862, 5321], 'labeling': [1871, 3889, 5348], 'experiment,': [1872, 3890, 5349], 'ECaC-injected': [1873, 2158, 2312, 3891, 4176, 4330, 5350], 'did': [1875, 3893, 5352], 'exhibit': [1877, 3895, 5354], '(0.88': [1882, 3900, 5359], '±': [1883, 1887, 2164, 2317, 3901, 3905, 4182, 4335, 5360, 5364], '0.05': [1884, 1888, 3902, 3906, 5361, 5365], '0.95': [1886, 3904, 5363], 'nmol·h−1·oocyte−1': [1889, 3907, 5366], 'water-injected': [1893, 2155, 3911, 4173, 5370], 'oocytes,': [1894, 3912, 5371], 'respectively;': [1895, 3913, 5372], 'n': [1896, 3914, 5373], '=': [1897, 3915, 5374], '29': [1898, 3916, 5375], 'oocytes;p': [1899, 3917, 5376], '0.2),': [1901, 3919, 5378], 'displaying': [1903, 3921, 5380], 'markedly': [1905, 3923, 5382], 'influx.': [1908, 3926, 5385], 'humans': [1910, 3928, 5387], 'metabolic': [1911, 3929, 5388], 'acidosis': [1912, 3930, 5389], 'induces': [1913, 3931, 5390], 'hypercalciuria': [1914, 2348, 2379, 3932, 4366, 4397, 5391, 5622, 5653], '20Sutton': [1930, 3948, 5407], 'R.A.L.': [1931, 3949, 5408], 'Wong': [1932, 3950, 5409], 'N.M.L.': [1933, 3951, 5410], 'Dirks': [1934, 3952, 5411], 'J.H.': [1935, 3953, 5412], 'Int.': [1937, 3955, 5414], '1979;': [1938, 3956, 5415], '15:': [1939, 3957, 5416], '520-533Abstract': [1940, 3958, 5417], '(207)': [1946, 3964, 5423], 'here': [1950, 3968, 5427], 'demonstrate': [1952, 3970, 5429], 'acidification': [1954, 3972, 5431], 'medium': [1958, 2293, 3976, 4311, 5435], 'pH': [1960, 2183, 2214, 3978, 4201, 4232, 5437], '5.9': [1961, 3979, 5438], 'inhibits45Ca2+': [1963, 3981, 5440], '5,': [1966, 2022, 3984, 4040, 5443, 5499], 'andB).': [1968, 3986, 5445], 'If': [1969, 3987, 5446], 'extrapolatable': [1970, 3988, 5447], 'vivo': [1974, 3992, 5451], 'situation': [1975, 3993, 5452], 'effect': [1977, 3995, 5454], 'could': [1978, 3996, 5455], 'explanation': [1983, 4001, 5460], 'acidosis-induced': [1985, 4003, 5462], 'calciuresis.': [1986, 4004, 5463], 'Taken': [1987, 4005, 5464], 'together,': [1988, 4006, 5465], 'characteristics': [1990, 2351, 4008, 4369, 5467, 5625], 'indicate': [1991, 4009, 5468], 'distinct': [1995, 4013, 5472], 'previously': [1997, 4015, 5474], 'described': [1998, 2004, 4016, 4022, 5475, 5481], 'Furthermore,': [2001, 4019, 5478], 'above': [2003, 4021, 5480], 'pharmacological': [2005, 4023, 5482], 'monolayers': [2020, 4038, 5497], 'D),': [2025, 4043, 5502], 'providing': [2026, 4044, 5503], 'evidence': [2027, 4045, 5504], 'major': [2033, 4051, 5510], 'constituent': [2034, 4052, 5511], 'system': [2040, 4058, 5517], 'Together': [2044, 4062, 5521], 'previous': [2047, 4065, 5524], 'finding': [2048, 4066, 5525], 'rate': [2053, 2130, 4071, 4148, 5530, 5607], 'tightly': [2063, 4081, 5540], 'coupled': [2064, 4082, 5541], 'flux': [2068, 4086, 5545], 'over': [2069, 4087, 5546], 'wide': [2071, 4089, 5548], 'rates': [2075, 4093, 5552], '(21Raber': [2076, 4094, 5553], 'Willems': [2078, 4096, 5555], 'P.H.G.M.': [2079, 4097, 5556], 'Lang': [2080, 4098, 5557], 'Nitsche': [2082, 4100, 5559], 'van': [2084, 4102, 5561], 'Bindels': [2087, 4105, 5564], 'R.J.M.': [2088, 4106, 5565], 'Calcium.': [2090, 4108, 5567], '22:': [2092, 4110, 5569], '157-166Crossref': [2093, 4111, 5570], '(19)': [2096, 4114, 5573], 'rate-limiting': [2108, 4126, 5585], 'step': [2109, 4127, 5586], 'Moreover,': [2114, 4132, 5591], 'hormonal': [2118, 4136, 5595], 'regulation': [2119, 4137, 5596], 'pathway,': [2124, 4142, 5601], 'i.e.': [2125, 4143, 5602], 'control': [2128, 4146, 5605], 'transport.Figure': [2134, 4152], '445Ca2+': [2135, 4153], 'expressing': [2139, 2193, 2270, 4157, 4211, 4288], 'function': [2143, 2405, 4161, 4423, 5679], 'time.': [2145, 4163], 'Measurements': [2146, 2281, 4164, 4299], 'performed': [2148, 2283, 4166, 4301], 'time': [2152, 4170], 'points': [2153, 4171], '(○)': [2156, 4174], '(●)': [2159, 4177], 'oocytes.': [2160, 2313, 4178, 4331], 'Values': [2161, 2314, 4179, 4332], 'means': [2163, 2316, 4181, 4334], 'S.E.': [2165, 2318, 4183, 4336], 'experiments.View': [2168, 4186], '(PPT)Figure': [2173, 4191], '5Functional': [2174, 4192], 'B,': [2180, 4198], 'substrate': [2181, 4199], 'specificity,': [2182, 4200], 'dependence,': [2184, 4202], 'voltage': [2186, 4204], 'dependence': [2187, 2264, 4205, 4282], 'transcellular45Ca2+': [2197, 2274, 4215, 4292], '(B).': [2203, 4221], 'Cations': [2204, 4222], 'added': [2206, 2239, 4224, 4257], 'final': [2209, 4227], '0.5': [2212, 4230], 'mm,': [2213, 4231], 'lowered': [2216, 4234], '7.4': [2218, 4236], '5.9,': [2220, 4238], 'NaCl': [2223, 4241], 'replaced': [2225, 4243], 'depolarize': [2231, 4249], 'methoxyverapamil': [2234, 4252], '(m-verapamil)': [2235, 4253], 'felodipine': [2237, 4255], 'μm.': [2242, 4260], 'measurements': [2247, 4265], 'additions': [2252, 4270], 'applied': [2254, 4272], 'only.': [2259, 4277], 'D,': [2262, 4280], '(D).': [2280, 4298], 'confluent': [2297, 4315], 'monolayers,': [2298, 4316], 'Water-injected': [2300, 4318], 'exhibited': [2302, 4320], '6%': [2309, 4327], 'five': [2320, 4338], 'experiments.': [2321, 4339], 'Statistical': [2322, 4340], 'significance': [2323, 4341], '(*,': [2324, 4342], 'p': [2325, 4343], '<': [2326, 4344], '0.05)': [2327, 4345], 'determined': [2329, 4347], 'variance.View': [2333, 4351], '(PPT)In': [2338, 4356], 'humans,': [2339, 4357, 5613], 'approximately': [2340, 4358, 5614], '4%': [2341, 4359, 5615], 'population': [2344, 4362, 5618], 'suffers': [2345, 4363, 5619], 'idiopathic': [2347, 4365, 5621], 'autosomal': [2353, 4371, 5627], 'dominant': [2354, 4372, 5628], 'transmission': [2355, 4373, 5629], '(22Asplin': [2356, 2386, 4374, 4404, 5630, 5660], 'J.R.': [2357, 2387, 4375, 4405, 5631, 5661], 'Favus': [2358, 2388, 4376, 4406, 5632, 5662], 'Coe': [2360, 2390, 4378, 4408, 5634, 5664], 'F.L.': [2361, 2391, 4379, 4409, 5635, 5665], '1893-1935Google': [2371, 2401, 4389, 4419, 5645, 5675], 'some': [2374, 4392, 5648], 'affected': [2377, 4395, 5651], 'individuals,': [2378, 4396, 5652], 'secondary': [2381, 4399, 5655], 'hyperabsorption': [2383, 4401, 5657], 'Gain': [2403, 4421, 5677], 'dysregulation': [2411, 4429, 5685], 'cause': [2416, 4434, 5690], 'absorptive': [2418, 4436, 5692], 'hypercalciuria.': [2419, 4437, 5693], 'elucidation': [2422, 4440, 5696], 'allows': [2425, 4443, 5699], 'study': [2427, 4445, 5701], 'possibilities': [2429, 4447, 5703], 'genetic': [2432, 4450, 5706], 'approaches.': [2433, 4451, 5707], 'RESULTS': [2899], 'Scholar).Immunofluorescence': [3538], 'Here,': [4452], '1B).': [4671], 'High': [4972], 'Immunofluorescence': [5092], 'gratefully': [5709], 'acknowledge': [5710], 'valuable': [5712], 'advice': [5713], 'Dr.': [5715], 'Jonathan': [5716], 'constructing': [5719], 'library,': [5723], 'superb': [5725], 'assistance': [5726], 'Judith': [5728], 'Nelissen': [5729], 'analysis,': [5733], 'thank': [5735], 'Drs.': [5736], 'Jan': [5737], 'Joep': [5738], 'de': [5739], 'Pont,': [5740], 'Bé': [5741], 'Wieringa,': [5742], 'Nine': [5744], 'Knoers': [5745], 'critical': [5747], 'manuscript.': [5751]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2120038848', 'counts_by_year': [{'year': 2024, 'cited_by_count': 9}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 14}, {'year': 2017, 'cited_by_count': 15}, {'year': 2016, 'cited_by_count': 12}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 17}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2024-12-14T02:51:31.084922', 'created_date': '2016-06-24'}