Publication Information

{'id': 'https://openalex.org/W2120009689', 'doi': 'https://doi.org/10.1128/aac.01412-09', 'title': '<i>In Vitro</i> Sensitivities of <i>Plasmodium falciparum</i> to Different Antimalarial Drugs in Uganda', 'display_name': '<i>In Vitro</i> Sensitivities of <i>Plasmodium falciparum</i> to Different Antimalarial Drugs in Uganda', 'publication_year': 2010, 'publication_date': '2010-01-12', 'ids': {'openalex': 'https://openalex.org/W2120009689', 'doi': 'https://doi.org/10.1128/aac.01412-09', 'mag': '2120009689', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20065051', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2825959'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/aac.01412-09', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2825959?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051310567', 'display_name': 'Samuel L. Nsobya', 'orcid': 'https://orcid.org/0000-0003-4986-8823'}, 'institutions': [{'id': 'https://openalex.org/I72227227', 'display_name': 'Makerere University', 'ror': 'https://ror.org/03dmz0111', 'country_code': 'UG', 'type': 'education', 'lineage': ['https://openalex.org/I72227227']}], 'countries': ['UG'], 'is_corresponding': False, 'raw_author_name': 'Samuel L. Nsobya', 'raw_affiliation_strings': ['Department of Medicine, Makerere University, Kampala, Uganda.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Makerere University, Kampala, Uganda.', 'institution_ids': ['https://openalex.org/I72227227']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010876550', 'display_name': 'Moses Ν. Kiggundu', 'orcid': 'https://orcid.org/0000-0001-9313-1939'}, 'institutions': [{'id': 'https://openalex.org/I72227227', 'display_name': 'Makerere University', 'ror': 'https://ror.org/03dmz0111', 'country_code': 'UG', 'type': 'education', 'lineage': ['https://openalex.org/I72227227']}], 'countries': ['UG'], 'is_corresponding': False, 'raw_author_name': 'Moses Kiggundu', 'raw_affiliation_strings': ['Department of Medicine, Makerere University, Kampala, Uganda.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Makerere University, Kampala, Uganda.', 'institution_ids': ['https://openalex.org/I72227227']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001016407', 'display_name': 'Sarah Nanyunja', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I72227227', 'display_name': 'Makerere University', 'ror': 'https://ror.org/03dmz0111', 'country_code': 'UG', 'type': 'education', 'lineage': ['https://openalex.org/I72227227']}], 'countries': ['UG'], 'is_corresponding': False, 'raw_author_name': 'Sarah Nanyunja', 'raw_affiliation_strings': ['Department of Medicine, Makerere University, Kampala, Uganda.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, Makerere University, Kampala, Uganda.', 'institution_ids': ['https://openalex.org/I72227227']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074967283', 'display_name': 'Moses Joloba', 'orcid': 'https://orcid.org/0000-0002-0334-9983'}, 'institutions': [{'id': 'https://openalex.org/I72227227', 'display_name': 'Makerere University', 'ror': 'https://ror.org/03dmz0111', 'country_code': 'UG', 'type': 'education', 'lineage': ['https://openalex.org/I72227227']}], 'countries': ['UG'], 'is_corresponding': False, 'raw_author_name': 'Moses Joloba', 'raw_affiliation_strings': ['Department of Microbiology, Makerere University, Kampala, Uganda'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Makerere University, Kampala, Uganda', 'institution_ids': ['https://openalex.org/I72227227']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054207126', 'display_name': 'Bryan Greenhouse', 'orcid': 'https://orcid.org/0000-0003-0287-9111'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Bryan Greenhouse', 'raw_affiliation_strings': ['Department of Medicine, University of California, San Francisco, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California, San Francisco, California', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077631479', 'display_name': 'Philip J. Rosenthal', 'orcid': 'https://orcid.org/0000-0002-7953-7622'}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Philip J. Rosenthal', 'raw_affiliation_strings': ['Department of Medicine, University of California, San Francisco, California'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of California, San Francisco, California', 'institution_ids': ['https://openalex.org/I180670191']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 10.754, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 88, 'citation_normalized_percentile': {'value': 0.926455, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '54', 'issue': '3', 'first_page': '1200', 'last_page': '1206'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10695', 'display_name': 'Parasites and Host Interactions', 'score': 0.9683, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10211', 'display_name': 'Computational Drug Discovery Methods', 'score': 0.9641, 'subfield': {'id': 'https://openalex.org/subfields/1703', 'display_name': 'Computational Theory and Mathematics'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/amodiaquine', 'display_name': 'Amodiaquine', 'score': 0.91949266}, {'id': 'https://openalex.org/keywords/dihydroartemisinin', 'display_name': 'Dihydroartemisinin', 'score': 0.8067033}, {'id': 'https://openalex.org/keywords/piperaquine', 'display_name': 'Piperaquine', 'score': 0.77493054}, {'id': 'https://openalex.org/keywords/lumefantrine', 'display_name': 'Lumefantrine', 'score': 0.6648032}, {'id': 'https://openalex.org/keywords/quinine', 'display_name': 'Quinine', 'score': 0.60699}], 'concepts': [{'id': 'https://openalex.org/C2776992834', 'wikidata': 'https://www.wikidata.org/wiki/Q239569', 'display_name': 'Amodiaquine', 'level': 4, 'score': 0.91949266}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.89182544}, {'id': 'https://openalex.org/C2781160685', 'wikidata': 'https://www.wikidata.org/wiki/Q5276420', 'display_name': 'Dihydroartemisinin', 'level': 5, 'score': 0.8067033}, {'id': 'https://openalex.org/C2777616469', 'wikidata': 'https://www.wikidata.org/wiki/Q7197338', 'display_name': 'Piperaquine', 'level': 5, 'score': 0.77493054}, {'id': 'https://openalex.org/C2777425658', 'wikidata': 'https://www.wikidata.org/wiki/Q422438', 'display_name': 'Chloroquine', 'level': 3, 'score': 0.70440006}, {'id': 'https://openalex.org/C2780780316', 'wikidata': 'https://www.wikidata.org/wiki/Q904464', 'display_name': 'Lumefantrine', 'level': 5, 'score': 0.6648032}, {'id': 'https://openalex.org/C2776120307', 'wikidata': 'https://www.wikidata.org/wiki/Q426921', 'display_name': 'Artemisinin', 'level': 4, 'score': 0.6426743}, {'id': 'https://openalex.org/C2777199930', 'wikidata': 'https://www.wikidata.org/wiki/Q736270', 'display_name': 'Mefloquine', 'level': 4, 'score': 0.633113}, {'id': 'https://openalex.org/C2777617192', 'wikidata': 'https://www.wikidata.org/wiki/Q189522', 'display_name': 'Quinine', 'level': 3, 'score': 0.60699}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.60315347}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.5969431}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.5912483}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.5898232}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.2378872}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.15301016}], 'mesh': [{'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000962', 'descriptor_name': 'Antimalarials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015331', 'descriptor_name': 'Cohort Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D016778', 'descriptor_name': 'Malaria, Falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D027425', 'descriptor_name': 'Multidrug Resistance-Associated Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D027425', 'descriptor_name': 'Multidrug Resistance-Associated Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021261', 'descriptor_name': 'Parasitic Sensitivity Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D021261', 'descriptor_name': 'Parasitic Sensitivity Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011110', 'descriptor_name': 'Polymorphism, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015800', 'descriptor_name': 'Protozoan Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014454', 'descriptor_name': 'Uganda', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/aac.01412-09', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S47215897', 'display_name': 'Antimicrobial Agents and Chemotherapy', 'issn_l': '0066-4804', 'issn': ['0066-4804', '1070-6283', '1098-6596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2825959', 'pdf_url': 'https://europepmc.org/articles/pmc2825959?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825959', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20065051', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2825959', 'pdf_url': 'https://europepmc.org/articles/pmc2825959?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.84, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 65, 'referenced_works': ['https://openalex.org/W139561384', 'https://openalex.org/W1694215848', 'https://openalex.org/W1838568970', 'https://openalex.org/W1950804392', 'https://openalex.org/W1964992513', 'https://openalex.org/W1972778967', 'https://openalex.org/W1977603169', 'https://openalex.org/W1982497887', 'https://openalex.org/W1991442399', 'https://openalex.org/W1996098609', 'https://openalex.org/W200090149', 'https://openalex.org/W2002346296', 'https://openalex.org/W2008166606', 'https://openalex.org/W2014392076', 'https://openalex.org/W2021704622', 'https://openalex.org/W2023687237', 'https://openalex.org/W2025054505', 'https://openalex.org/W2040713555', 'https://openalex.org/W2051633841', 'https://openalex.org/W2052262611', 'https://openalex.org/W2069047837', 'https://openalex.org/W2089028621', 'https://openalex.org/W2096355268', 'https://openalex.org/W2097263871', 'https://openalex.org/W2100343162', 'https://openalex.org/W2100435538', 'https://openalex.org/W2101029348', 'https://openalex.org/W2101114302', 'https://openalex.org/W2101536758', 'https://openalex.org/W2104355399', 'https://openalex.org/W2104536143', 'https://openalex.org/W2106346927', 'https://openalex.org/W2109191053', 'https://openalex.org/W2111813303', 'https://openalex.org/W2115398829', 'https://openalex.org/W2118266103', 'https://openalex.org/W2121790784', 'https://openalex.org/W2123081467', 'https://openalex.org/W2123618955', 'https://openalex.org/W2125109931', 'https://openalex.org/W2125397010', 'https://openalex.org/W2126585535', 'https://openalex.org/W2131867921', 'https://openalex.org/W2132671212', 'https://openalex.org/W2132923209', 'https://openalex.org/W2134016435', 'https://openalex.org/W2135192999', 'https://openalex.org/W2137601868', 'https://openalex.org/W2137636253', 'https://openalex.org/W2138754677', 'https://openalex.org/W2139149700', 'https://openalex.org/W2142725656', 'https://openalex.org/W2145933399', 'https://openalex.org/W2150269854', 'https://openalex.org/W2150522686', 'https://openalex.org/W2152312680', 'https://openalex.org/W2152672321', 'https://openalex.org/W2159307889', 'https://openalex.org/W2161311583', 'https://openalex.org/W2163765308', 'https://openalex.org/W2165454717', 'https://openalex.org/W2168521097', 'https://openalex.org/W2187436842', 'https://openalex.org/W2333050857', 'https://openalex.org/W2396351265'], 'related_works': ['https://openalex.org/W4235794007', 'https://openalex.org/W4229594506', 'https://openalex.org/W3152036712', 'https://openalex.org/W3117177187', 'https://openalex.org/W2486718290', 'https://openalex.org/W2418699445', 'https://openalex.org/W2150873418', 'https://openalex.org/W2120009689', 'https://openalex.org/W2101775642', 'https://openalex.org/W2040594839'], 'abstract_inverted_index': {'ABSTRACT': [0], 'The': [1, 87], 'control': [2], 'of': [3, 9, 24, 31, 45, 71, 80, 94, 105, 231, 237], 'malaria': [4], 'is': [5, 36], 'challenged': [6], 'by': [7, 68], 'resistance': [8, 32, 123], 'Plasmodium': [10], 'falciparum': [11, 26, 47], 'to': [12, 33, 63, 96, 132, 179, 198, 217, 233, 239], 'multiple': [13], 'drugs.': [14], 'New': [15], 'combination': [16], 'regimens': [17], 'are': [18], 'now': [19], 'advocated': [20], 'for': [21, 122, 124, 251], 'the': [22, 29, 41, 101, 147, 184, 203], 'treatment': [23], 'uncomplicated': [25], 'malaria,': [27], 'but': [28, 145], 'extent': [30], 'newer': [34], 'agents': [35], 'incompletely': [37], 'understood.': [38], 'We': [39, 157], 'measured': [40, 67], 'in': [42, 53, 58, 74, 84, 163, 192, 211, 225], 'vitro': [43], 'sensitivity': [44], 'P.': [46], 'parasites': [48, 75, 89, 172, 193, 212, 226], 'cultured': [49, 88], 'from': [50, 61, 227], 'children': [51], 'enrolled': [52], 'a': [54, 91, 229], 'drug': [55, 181], 'efficacy': [56], 'trial': [57], 'Kampala,': [59], 'Uganda,': [60], '2006': [62], '2008.': [64], 'Sensitivities': [65], 'were': [66, 118, 129, 154, 174, 182, 195, 214], 'comparing': [69], 'levels': [70], 'histidine-rich': [72], 'protein-2': [73], 'incubated': [76], 'with': [77, 82], 'different': [78], 'concentrations': [79], 'drugs': [81], 'those': [83], 'untreated': [85], 'controls.': [86], 'exhibited': [90], 'wide': [92], 'range': [93, 230], 'sensitivities': [95, 232, 238], 'chloroquine': [97], '(CQ);': [98], 'monodesethylamodiaquine': [99], '(MDAQ),': [100], 'major': [102], 'active': [103], 'metabolite': [104], 'amodiaquine;': [106], 'and': [107, 126, 137, 143, 168, 176, 200, 202, 219, 242, 244, 254], 'quinine': [108], '(QN).': [109], 'Mean': [110], '50%': [111], 'inhibitory': [112], 'concentration': [113], '(IC': [114], '50': [115], ')': [116], 'results': [117], 'above': [119], 'standard': [120], 'cutoffs': [121], 'CQ': [125, 199], 'MDAQ.': [127], 'Parasites': [128], 'generally': [130], 'sensitive': [131, 178], 'dihydroartemisinin': [133], '(DHA),': [134], 'lumefantrine': [135], '(LM),': [136], 'piperaquine': [138], '(PQ).': [139], 'For': [140], 'CQ,': [141, 240], 'MDAQ,': [142, 201, 241], 'QN': [144], 'not': [146], 'other': [148], 'drugs,': [149], 'activities': [150], 'against': [151, 247], 'individual': [152], 'strains': [153, 250], 'highly': [155], 'correlated.': [156], 'also': [158], 'assessed': [159], 'known': [160], 'resistance-mediating': [161], 'polymorphisms': [162], 'two': [164], 'putative': [165], 'transporters,': [166], 'pfcrt': [167], 'pfmdr1': [169, 185, 204], '.': [170], 'When': [171], 'that': [173, 194, 213], 'least': [175], 'most': [177, 196, 215], 'each': [180], 'compared,': [183], '86Y': [186], 'mutation': [187, 206], 'was': [188, 207], 'significantly': [189, 208], 'more': [190, 209], 'common': [191, 210], 'resistant': [197, 216], 'D1246Y': [205], 'MDAQ': [218], 'QN.': [220], 'In': [221], 'summary,': [222], 'we': [223], 'demonstrated': [224], 'Kampala': [228], 'older': [234], 'drugs;': [235], 'correlation': [236], 'QN;': [243], 'good': [245], 'activity': [246], 'nearly': [248], 'all': [249], 'DHA,': [252], 'LM,': [253], 'PQ.': [255]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2120009689', 'counts_by_year': [{'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 10}], 'updated_date': '2024-12-15T20:03:07.899315', 'created_date': '2016-06-24'}