A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins

Name: Work Video:
Duration: 3 min 30 s
Westley J. Friesen; Anastasia Wyce; Sergey Paushkin; Linda Abel; Juri Rappsilber; Matthias Mann; Gideon Dreyfuss
{'id': 'https://openalex.org/W2119931165', 'doi': 'https://doi.org/10.1074/jbc.m109984200', 'title': 'A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins', 'display_name': 'A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins', 'publication_year': 2002, 'publication_date': '2002-03-01', 'ids': {'openalex': 'https://openalex.org/W2119931165', 'doi': 'https://doi.org/10.1074/jbc.m109984200', 'mag': '2119931165', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11756452'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m109984200', 'pdf_url': 'http://www.jbc.org/article/S0021925819364245/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925819364245/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027242687', 'display_name': 'Westley J. Friesen', 'orcid': 'https://orcid.org/0000-0002-6191-2973'}, 'institutions': [{'id': 'https://openalex.org/I79576946', 'display_name': 'University of Pennsylvania', 'ror': 'https://ror.org/00b30xv10', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79576946']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Westley J. Friesen', 'raw_affiliation_strings': ['Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the', 'institution_ids': ['https://openalex.org/I79576946']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061730687', 'display_name': 'Anastasia Wyce', 'orcid': 'https://orcid.org/0000-0003-2294-3096'}, 'institutions': [{'id': 'https://openalex.org/I79576946', 'display_name': 'University of Pennsylvania', 'ror': 'https://ror.org/00b30xv10', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79576946']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anastasia Wyce', 'raw_affiliation_strings': ['Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the', 'institution_ids': ['https://openalex.org/I79576946']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021361416', 'display_name': 'Sergey Paushkin', 'orcid': 'https://orcid.org/0000-0003-3862-0996'}, 'institutions': [{'id': 'https://openalex.org/I79576946', 'display_name': 'University of Pennsylvania', 'ror': 'https://ror.org/00b30xv10', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79576946']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sergey Paushkin', 'raw_affiliation_strings': ['Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the', 'institution_ids': ['https://openalex.org/I79576946']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023363690', 'display_name': 'Linda Abel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I79576946', 'display_name': 'University of Pennsylvania', 'ror': 'https://ror.org/00b30xv10', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79576946']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Linda Abel', 'raw_affiliation_strings': ['Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the', 'institution_ids': ['https://openalex.org/I79576946']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076844877', 'display_name': 'Juri Rappsilber', 'orcid': 'https://orcid.org/0000-0001-5999-1310'}, 'institutions': [{'id': 'https://openalex.org/I177969490', 'display_name': 'University of Southern Denmark', 'ror': 'https://ror.org/03yrrjy16', 'country_code': 'DK', 'type': 'education', 'lineage': ['https://openalex.org/I177969490']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Juri Rappsilber', 'raw_affiliation_strings': ['Protein Interaction Laboratory, Center for Experimental Bioinformatics and Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Protein Interaction Laboratory, Center for Experimental Bioinformatics and Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark', 'institution_ids': ['https://openalex.org/I177969490']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090940750', 'display_name': 'Matthias Mann', 'orcid': 'https://orcid.org/0000-0003-1292-4799'}, 'institutions': [{'id': 'https://openalex.org/I177969490', 'display_name': 'University of Southern Denmark', 'ror': 'https://ror.org/03yrrjy16', 'country_code': 'DK', 'type': 'education', 'lineage': ['https://openalex.org/I177969490']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Matthias Mann', 'raw_affiliation_strings': ['Protein Interaction Laboratory, Center for Experimental Bioinformatics and Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Protein Interaction Laboratory, Center for Experimental Bioinformatics and Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense M, Denmark', 'institution_ids': ['https://openalex.org/I177969490']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5059044460', 'display_name': 'Gideon Dreyfuss', 'orcid': 'https://orcid.org/0000-0001-8129-8774'}, 'institutions': [{'id': 'https://openalex.org/I79576946', 'display_name': 'University of Pennsylvania', 'ror': 'https://ror.org/00b30xv10', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79576946']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gideon Dreyfuss', 'raw_affiliation_strings': ['Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-6148 and the', 'institution_ids': ['https://openalex.org/I79576946']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 3.05, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 226, 'citation_normalized_percentile': {'value': 0.999975, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '277', 'issue': '10', 'first_page': '8243', 'last_page': '8247'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9783, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9223, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/component', 'display_name': 'Component (thermodynamics)', 'score': 0.53296405}], 'concepts': [{'id': 'https://openalex.org/C168167062', 'wikidata': 'https://www.wikidata.org/wiki/Q1117970', 'display_name': 'Component (thermodynamics)', 'level': 2, 'score': 0.53296405}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.42999634}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.3666985}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.32739294}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.11732614}, {'id': 'https://openalex.org/C97355855', 'wikidata': 'https://www.wikidata.org/wiki/Q11473', 'display_name': 'Thermodynamics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D048868', 'descriptor_name': 'Adaptor Proteins, Signal Transducing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011484', 'descriptor_name': 'Protein-Arginine N-Methyltransferases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002499', 'descriptor_name': 'Centrifugation, Density Gradient', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004591', 'descriptor_name': 'Electrophoresis, Polyacrylamide Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015151', 'descriptor_name': 'Immunoblotting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008745', 'descriptor_name': 'Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011496', 'descriptor_name': 'Protein Methyltransferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011496', 'descriptor_name': 'Protein Methyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011484', 'descriptor_name': 'Protein-Arginine N-Methyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020449', 'descriptor_name': 'Repetitive Sequences, Amino Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D017411', 'descriptor_name': 'Ribonucleoproteins, Small Nuclear', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m109984200', 'pdf_url': 'http://www.jbc.org/article/S0021925819364245/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11756452', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m109984200', 'pdf_url': 'http://www.jbc.org/article/S0021925819364245/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 56, 'referenced_works': ['https://openalex.org/W107708601', 'https://openalex.org/W150114986', 'https://openalex.org/W163733949', 'https://openalex.org/W1887299981', 'https://openalex.org/W1966809971', 'https://openalex.org/W1969988975', 'https://openalex.org/W1970569586', 'https://openalex.org/W1973279131', 'https://openalex.org/W1976147540', 'https://openalex.org/W1978550291', 'https://openalex.org/W1979906352', 'https://openalex.org/W1980477780', 'https://openalex.org/W1990033911', 'https://openalex.org/W1996412713', 'https://openalex.org/W1998918411', 'https://openalex.org/W2001323818', 'https://openalex.org/W2001628772', 'https://openalex.org/W2010973571', 'https://openalex.org/W2011991138', 'https://openalex.org/W2027100849', 'https://openalex.org/W2027863760', 'https://openalex.org/W2028149832', 'https://openalex.org/W2028903990', 'https://openalex.org/W2030107543', 'https://openalex.org/W2030185192', 'https://openalex.org/W2050406900', 'https://openalex.org/W2052280808', 'https://openalex.org/W2054236204', 'https://openalex.org/W2054669239', 'https://openalex.org/W2059590797', 'https://openalex.org/W2059997993', 'https://openalex.org/W2062577265', 'https://openalex.org/W2073409278', 'https://openalex.org/W2074697255', 'https://openalex.org/W2077520688', 'https://openalex.org/W2077673061', 'https://openalex.org/W2085465310', 'https://openalex.org/W2089065260', 'https://openalex.org/W2090582665', 'https://openalex.org/W2091533776', 'https://openalex.org/W2096575861', 'https://openalex.org/W2096650232', 'https://openalex.org/W2108959187', 'https://openalex.org/W2121141232', 'https://openalex.org/W2121542423', 'https://openalex.org/W2130400516', 'https://openalex.org/W2136050657', 'https://openalex.org/W2136635540', 'https://openalex.org/W2136906322', 'https://openalex.org/W2137891310', 'https://openalex.org/W2138148973', 'https://openalex.org/W2143356450', 'https://openalex.org/W2143855758', 'https://openalex.org/W2153111398', 'https://openalex.org/W2160875554', 'https://openalex.org/W2170186108'], 'related_works': ['https://openalex.org/W4391375266', 'https://openalex.org/W4387497383', 'https://openalex.org/W2948807893', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2527526854', 'https://openalex.org/W2078814861', 'https://openalex.org/W1986764834', 'https://openalex.org/W1976181487', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'We': [0, 86, 170, 256, 1692, 2089, 2948, 3568, 3954, 4403, 4653, 5202, 5696], 'have': [1, 171, 1340, 1693, 2336, 2949, 4404, 4638, 4719], 'recently': [2, 172, 1694, 2950, 4405], 'described': [3, 173, 2339, 2439, 2537, 2695, 2730, 2791, 3643, 3979], 'a': [4, 71, 77, 101, 111, 174, 241, 247, 271, 281, 365, 377, 449, 802, 1214, 1709, 1822, 1917, 2079, 2093, 2114, 2502, 2996, 3006, 3084, 3101, 3160, 3252, 3279, 3314, 3395, 3447, 3542, 3565, 3605, 3789, 3962, 4045, 4412, 4472, 4599, 4631, 4641, 4834, 5068, 5073, 5120, 5168, 5300, 5308, 5381, 5398, 5404, 5689], 'large': [5, 175, 637, 803, 1710, 2115, 3728, 4473, 5190], '(20': [6, 176, 2605, 3487], 'S)': [7, 177, 3488], 'protein': [8, 81, 83, 115, 162, 178, 251, 253, 285, 332, 1217, 1512, 1659, 1719, 1876, 1962, 2082, 2120, 2131, 2262, 2328, 2334, 2374, 2385, 2428, 2565, 2788, 2998, 3085, 3161, 3280, 4018, 4059, 4305, 4455, 4514, 5069, 5213, 5229, 5384, 5584, 5635, 5679], 'arginine': [9, 179, 1375, 4513], 'methyltransferase': [10, 18, 180, 188, 2958, 4111], 'complex,': [11, 154, 181, 324, 804, 2012, 2985, 4460], 'termed': [12, 182, 2087, 4476], 'the': [13, 17, 22, 35, 52, 75, 122, 128, 133, 137, 152, 155, 183, 187, 192, 205, 222, 245, 292, 298, 303, 307, 322, 325, 395, 398, 405, 453, 457, 463, 466, 476, 626, 639, 647, 788, 895, 1042, 1224, 1240, 1249, 1704, 1707, 1717, 1825, 1860, 1869, 1882, 1965, 2001, 2010, 2085, 2128, 2134, 2179, 2295, 2298, 2316, 2518, 2574, 2672, 2914, 2953, 2957, 2961, 2966, 2974, 2978, 3090, 3114, 3134, 3173, 3244, 3261, 3288, 3303, 3324, 3403, 3431, 3436, 3472, 3476, 3485, 3505, 3533, 3546, 3555, 3571, 3574, 3577, 3717, 3727, 3731, 3741, 3746, 3773, 3851, 3917, 3928, 3940, 3950, 4015, 4035, 4038, 4057, 4062, 4065, 4069, 4078, 4094, 4098, 4110, 4114, 4120, 4268, 4275, 4282, 4286, 4303, 4419, 4452, 4458, 4461, 4477, 4522, 4535, 4603, 4606, 4617, 4622, 4651, 4671, 4674, 4689, 4713, 4766, 4851, 4862, 4875, 4954, 4960, 4963, 5030, 5053, 5078, 5117, 5125, 5135, 5146, 5152, 5175, 5184, 5196, 5199, 5244, 5254, 5257, 5262, 5272, 5275, 5283, 5524, 5535, 5611, 5616, 5670, 5682, 5692, 5715], 'methylosome,': [14, 76, 184, 246, 1708, 2002, 2954, 3115, 3437, 3747, 4039], 'that': [15, 88, 143, 185, 258, 313, 625, 1223, 1696, 1714, 1957, 2091, 2123, 2174, 2886, 2902, 2952, 3078, 3104, 3240, 3285, 3305, 3331, 3538, 3562, 3710, 3721, 3919, 3934, 3944, 4105, 4407, 4656, 4678, 4710, 4728, 4761, 4951, 5063, 5070, 5155, 5174, 5193, 5204, 5243, 5267, 5293, 5392, 5518, 5602, 5669, 5685], 'contains': [16, 186, 1716, 2956, 3333, 4511], 'JBP1': [19, 98, 189, 268, 361, 1515, 1697, 1873, 2100, 2387, 2506, 2959, 3001, 3038, 3054, 3069, 3094, 3154, 3596, 3632, 3703, 3724, 4762, 4772, 4811, 4824, 5250, 5629], '(PRMT5)': [20, 190], 'and': [21, 37, 45, 95, 99, 191, 207, 215, 265, 269, 376, 389, 397, 472, 634, 646, 859, 1040, 1242, 1254, 1391, 1634, 1701, 1816, 1938, 2101, 2104, 2150, 2164, 2220, 2263, 2305, 2366, 2376, 2421, 2434, 2515, 2530, 2571, 2621, 2655, 2725, 2775, 2782, 2852, 2922, 2937, 2960, 3005, 3035, 3051, 3059, 3110, 3127, 3140, 3150, 3155, 3175, 3238, 3271, 3307, 3318, 3418, 3444, 3453, 3457, 3467, 3491, 3511, 3517, 3524, 3582, 3586, 3600, 3619, 3629, 3641, 3719, 3751, 3759, 3806, 3812, 3821, 3830, 3864, 3886, 3943, 4011, 4021, 4040, 4125, 4280, 4295, 4527, 4611, 4619, 4661, 4685, 4699, 4756, 4780, 4838, 4869, 5083, 5148, 5198, 5231, 5581, 5607, 5680, 5706, 5712], 'pICln': [23, 193, 1718, 1880, 1958, 2361, 2962, 3156, 3306, 3598, 3628, 5608], 'protein.': [24, 194, 3405], 'The': [25, 195, 443, 1116, 1210, 1506, 2360, 2430, 2778, 2926, 2941, 3063, 3832, 4116, 4509, 4667, 5130, 5378, 5598], 'methylosome': [26, 93, 138, 156, 196, 263, 308, 326, 349, 648, 1826, 1870, 1966, 2086, 2108, 2779, 2828, 3397, 3477, 3486, 3556, 3566, 3718, 3965, 4054, 4478, 4510, 4604, 4623, 4665, 4675, 4717, 4852, 5031, 5079, 5126, 5136, 5197, 5209, 5220, 5276, 5536, 5617, 5671], 'functions': [27, 197, 1396, 1702, 2125, 2964, 4957], 'to': [28, 32, 51, 97, 100, 120, 146, 198, 202, 221, 267, 270, 290, 316, 808, 1239, 1257, 1334, 1344, 1754, 1793, 1868, 2099, 2126, 2152, 2671, 2784, 2939, 2968, 3227, 3277, 3302, 3463, 3513, 3595, 3726, 3738, 3772, 3785, 3819, 3854, 3937, 3957, 4013, 4030, 4074, 4272, 4297, 4529, 4534, 4615, 4726, 4765, 4825, 4841, 4843, 4958, 5157, 5182, 5218, 5249, 5277, 5509, 5534, 5547, 5674], 'modify': [29, 199], 'specific': [30, 200, 2971, 4416, 4519, 4835], 'arginines': [31, 201, 2972, 4417, 4520, 5154], 'dimethylarginines': [33, 203, 1347], 'in': [34, 144, 160, 204, 314, 330, 394, 410, 462, 584, 627, 797, 806, 892, 1049, 1125, 1232, 1263, 1394, 1700, 1703, 1818, 1871, 1942, 2285, 2332, 2372, 2599, 2679, 2764, 2918, 2965, 2973, 3032, 3300, 3471, 3528, 3748, 3964, 4300, 4418, 4521, 4605, 4624, 4752, 4833, 4865, 5084, 5127, 5160, 5292, 5636, 5691], 'arginine-': [36, 206, 1241], 'glycine-rich': [38, 208, 1243], 'domains': [39, 209, 1245, 1337, 1661, 2976, 4299, 4421, 4524], 'of': [40, 54, 74, 103, 124, 132, 136, 210, 224, 244, 273, 294, 302, 306, 344, 380, 456, 465, 641, 888, 897, 1044, 1212, 1237, 1246, 1248, 1706, 1824, 1859, 1950, 2084, 2130, 2178, 2259, 2288, 2297, 2505, 2602, 2625, 2646, 2826, 2836, 2845, 2855, 2870, 2875, 2883, 2893, 2899, 2909, 2977, 3000, 3074, 3086, 3093, 3113, 3162, 3243, 3254, 3281, 3316, 3433, 3545, 3576, 3716, 3723, 3730, 3745, 3777, 3839, 3848, 3850, 3927, 3939, 4037, 4064, 4084, 4097, 4113, 4122, 4277, 4285, 4302, 4307, 4415, 4422, 4457, 4525, 4608, 4621, 4650, 4670, 4673, 4682, 4712, 4735, 4768, 4850, 4861, 4874, 4962, 5075, 5119, 5132, 5134, 5151, 5164, 5178, 5186, 5246, 5256, 5274, 5380, 5388, 5395, 5600, 5613, 5615, 5621, 5694, 5699], 'several': [41, 211, 3234, 3938, 4301, 4873], 'spliceosomal': [42, 212, 363, 4123, 4462], 'Sm': [43, 104, 140, 161, 213, 274, 310, 331, 381, 444, 454, 1250, 1658, 1795, 1864, 1875, 1883, 1954, 1961, 2003, 2102, 2327, 2787, 2979, 3739, 3841, 3852, 3941, 4017, 4058, 4464, 4659, 4856, 4876, 4964, 5037, 5043, 5139, 5212, 5228, 5280, 5525], 'proteins,': [44, 141, 214, 311, 1955, 3185, 3740, 4465, 5513, 5526, 5533, 5624], 'this': [46, 216, 2984, 3968, 4290, 4408, 4466, 4730, 4769, 5057, 5115, 5393], 'modification': [47, 217, 1999, 4414, 4467], 'targets': [48, 218], 'these': [49, 219, 1335, 2765, 3409, 3840, 3858, 3920, 3945, 4266, 4278], 'proteins': [50, 109, 220, 279, 382, 445, 1251, 1796, 1865, 2004, 2103, 2112, 2432, 2583, 2596, 2650, 2661, 3312, 3614, 3801, 3853, 3942, 4425, 4660, 4696, 4738, 4877, 4965, 5038, 5044, 5140, 5281, 5289, 5396, 5412, 5542, 5601], 'survival': [53, 223, 343, 640], 'motor': [55, 225, 345, 642, 1045], 'neurons': [56, 226, 346], '(SMN)': [57, 227, 644], 'complex': [58, 228, 633, 645, 1118, 1226, 1713, 4118, 4270, 4475, 4537, 4731, 4864, 4956], 'for': [59, 92, 113, 151, 167, 229, 262, 283, 321, 337, 1121, 1260, 2009, 2107, 2118, 2257, 2284, 2294, 2331, 2371, 2382, 2425, 2634, 2861, 3011, 3828, 4109, 4538, 4602, 4664, 4816, 5045, 5124, 5145, 5226, 5235, 5253, 5271, 5522, 5537, 5709], 'assembly': [60, 230, 630, 1124, 1266, 1820, 2017, 4121, 4539, 4961, 5048, 5180], 'into': [61, 231, 404, 448, 2018, 2222, 2264, 2321, 2368, 2377, 2423, 4540, 4846, 4966, 5049], 'small': [62, 232, 340], 'nuclear': [63, 233, 341, 411], 'ribonucleoprotein': [64, 234, 342], '(snRNP)': [65, 235], 'core': [66, 236, 367, 1123, 1265], 'particles.': [67, 237], 'Here,': [68, 238, 2076, 4627], 'we': [69, 239, 2077, 2986, 3116, 3411, 3913, 4612, 4637], 'describe': [70, 240, 2078], 'novel': [72, 242, 2080, 2094, 3543, 4642], 'component': [73, 243, 1823, 2083, 3544, 3715, 4649], '50-kilodalton': [78, 248, 2081, 3168], 'WD': [79, 107, 249, 277, 2095, 2110, 2307, 3335, 3767, 3774, 3814, 3951, 4643, 5287, 5382], 'repeat': [80, 108, 250, 278, 2096, 2111, 3768, 3775, 3952, 4644, 5383], 'termedmethylosome': [82, 252], '50': [84, 254, 3164], '(MEP50).': [85, 255, 3166], 'show': [87, 257, 2090, 4655, 5203], 'MEP50': [89, 117, 259, 287, 2124, 2290, 2318, 2556, 2564, 2942, 3250, 3308, 3332, 3393, 3404, 3414, 3419, 3434, 3469, 3518, 3525, 3539, 3551, 3563, 3587, 3601, 3630, 3711, 3736, 3935, 3960, 4106, 4657, 4747, 5064, 5216, 5222, 5247, 5268, 5505], 'is': [90, 260, 460, 621, 632, 795, 1119, 1698, 1916, 1939, 2105, 2946, 3100, 3275, 3540, 3564, 3712, 3910, 4107, 4468, 4662, 4680, 4708, 4724, 4732, 4740, 4759, 4859, 4949, 5060, 5071, 5172, 5240, 5251, 5261, 5265, 5269, 5506, 5520], 'important': [91, 261, 4108, 4663, 5144, 5225, 5252, 5270, 5521], 'activity': [94, 264, 4036, 4055, 4112, 4620, 5210, 5255], 'binds': [96, 266, 1332, 1874, 1881, 2098, 3737, 3936, 4293, 4658], 'subset': [102, 272], 'proteins.': [105, 275, 2980, 3842, 4857, 5166], 'Because': [106, 276, 4687], 'provide': [110, 280, 2113], 'platform': [112, 282, 5406], 'multiple': [114, 125, 284, 295, 2119, 2159, 4828, 5411, 5512], 'interactions,': [116, 286, 2121], 'may': [118, 157, 288, 327, 1959, 3295, 3922, 4813, 4821, 5039, 5141, 5223, 5609, 5672, 5687], 'function': [119, 289, 409, 1262, 1817, 5194, 5273, 5673], 'mediate': [121, 291, 2127], 'interaction': [123, 293, 2129, 4409, 5131, 5409], 'substrates': [126, 150, 296, 320, 2008, 2132, 2789, 3744, 4019, 4456, 4829, 5230, 5614], 'with': [127, 297, 468, 1964, 2133, 2501, 2520, 2563, 2576, 2588, 2643, 2685, 2833, 2867, 2890, 2906, 2931, 2995, 3042, 3124, 3142, 3313, 3402, 3435, 3493, 3498, 3554, 3591, 3607, 3764, 3791, 4087, 4630, 4855, 5066, 5138, 5282, 5410, 5511, 5604], 'methylosome.': [129, 299, 2135, 3547, 3578, 3732, 4115, 4652], 'Interestingly,': [130, 300], 'all': [131, 301, 798, 898, 2177, 3242, 4711, 4849, 4871, 5133], 'known': [134, 304, 1575, 3184, 5544], 'components': [135, 305, 583, 3112, 3575, 3926, 4276, 4306, 4672, 4718, 4853, 5137], 'bind': [139, 309, 1794, 4872], 'suggesting': [142, 312, 1956, 2122, 4777, 5668], 'addition': [145, 315, 807], 'producing': [147, 317, 5035], 'properly': [148, 318, 5232], 'methylated': [149, 319, 5036], 'SMN': [153, 323, 893, 1117, 1225, 1238, 1261, 1331, 2011, 4117, 4269, 4292, 4459, 4536, 4863, 4955, 5054, 5200], 'be': [158, 328, 1258, 1755, 3296, 3923, 4814, 5143, 5158, 5224, 5516], 'involved': [159, 329, 1393], 'rearrangements': [163, 333, 4284], 'or': [164, 334, 374, 889, 1386, 1514, 2848, 2880, 2896, 3497, 3637, 3779, 4748], 'pre-assembly': [165, 335], 'required': [166, 336, 1259, 2106, 4815], 'snRNP': [168, 338, 391, 575, 629, 1122, 1233, 1264, 1819, 4463, 4609, 4967, 5050, 5128, 5179], 'biogenesis.': [169, 339], 'symmetric': [347, 1346], 'dimethylarginine': [348, 1381], 'protein50': [350], 'glutathione': [351], 'S-transferase': [352], 'nanoelectrospray': [353, 2184], 'tandem': [354, 2185], 'mass': [355, 2186, 3264, 3291], 'spectrometry': [356, 2187], 'normal': [357, 2876], 'mouse': [358, 2877], 'serum': [359, 2878, 2885, 2901, 4070, 4086], 'flag-tagged': [360, 3037], 'Each': [362], 'snRNP1contains': [364], 'common': [366, 5301, 5309], 'comprising': [368], 'an': [369, 1228, 1756, 2154, 3229, 4512, 4647, 4778], 'snRNA': [370], '(U1,': [371], 'U2,': [372], 'U4,': [373], 'U5)': [375], 'seven-member': [378], 'ring': [379, 450, 467], '(B,': [383], 'D1,': [384], 'D2,': [385], 'D3,': [386], 'E,': [387], 'F,': [388], 'G).': [390], 'cores': [392, 576, 2020, 4968, 5051], 'assemble': [393, 578], 'cytoplasm,': [396], 'mature': [399], 'snRNPs': [400, 2019, 4124, 4541], 'are': [401, 1392, 1866, 3309, 3947, 5290, 5295, 5543], 'subsequently': [402, 1789], 'imported': [403], 'nucleus': [406], 'where': [407], 'they': [408, 1339, 4033, 5294], 'pre-mRNA': [412], 'splicing': [413], '(1Will': [414], 'C.L.': [415, 605, 975], 'Luhrmann': [416, 492, 518, 534, 590, 608, 695, 1173, 4152, 4993, 5097, 5563], 'R.': [417, 431, 483, 493, 519, 535, 591, 609, 696, 923, 1174, 1589, 1920, 2400, 4153, 4994, 5098, 5564], 'Curr.': [418, 1055, 4218, 4358], 'Opin.': [419, 1056], 'Cell': [420, 849, 876, 2271, 2544, 2710, 3019, 4200, 4340, 4913, 4938], 'Biol.': [421, 433, 565, 778, 850, 877, 905, 1025, 1294, 1406, 1529, 1559, 1619, 1641, 1683, 1741, 1807, 1848, 1906, 1988, 2067, 2245, 2272, 2345, 2462, 2545, 2711, 2753, 2814, 3020, 3666, 3688, 3871, 4002, 4201, 4219, 4248, 4314, 4341, 4359, 4388, 4500, 4587, 4796, 4914, 4939, 5100, 5566, 5653], '2001;': [422, 522, 543, 566, 744, 779, 907, 1361, 1453, 1561, 1684, 1742, 1849, 1907, 1989, 2033, 2068, 2246, 2463, 2754, 2815, 3667, 3690, 4003, 4202, 4220, 4250, 4342, 4360, 4390, 4438, 4501, 4554, 4588, 4798, 5655], '13:': [423], '290-301Crossref': [424], 'PubMed': [425, 438, 507, 525, 546, 569, 597, 615, 666, 686, 705, 727, 752, 782, 830, 854, 881, 915, 944, 967, 986, 1007, 1035, 1061, 1094, 1111, 1144, 1164, 1183, 1205, 1284, 1304, 1325, 1369, 1410, 1433, 1461, 1483, 1501, 1539, 1569, 1602, 1629, 1651, 1687, 1745, 1783, 1811, 1852, 1910, 1933, 1992, 2041, 2071, 2208, 2249, 2276, 2355, 2413, 2466, 2487, 2549, 2715, 2757, 2818, 3024, 3209, 3359, 3385, 3670, 3698, 3881, 3903, 4006, 4143, 4162, 4184, 4205, 4228, 4258, 4324, 4345, 4368, 4398, 4446, 4504, 4562, 4591, 4806, 4895, 4918, 4943, 4984, 5003, 5025, 5110, 5330, 5355, 5373, 5434, 5459, 5478, 5499, 5576, 5593, 5663], 'Scopus': [426, 439, 508, 526, 547, 570, 598, 616, 667, 687, 706, 728, 753, 783, 831, 855, 882, 916, 945, 968, 987, 1008, 1036, 1062, 1095, 1112, 1145, 1165, 1184, 1206, 1285, 1305, 1326, 1370, 1434, 1462, 1484, 1502, 1540, 1570, 1603, 1630, 1652, 1688, 1746, 1784, 1812, 1853, 1911, 1934, 1993, 2042, 2072, 2209, 2250, 2277, 2356, 2414, 2467, 2488, 2550, 2716, 2758, 2819, 3025, 3210, 3360, 3386, 3671, 3699, 3882, 3904, 4007, 4144, 4163, 4185, 4206, 4229, 4259, 4325, 4346, 4369, 4399, 4447, 4505, 4563, 4592, 4807, 4896, 4919, 4944, 4985, 5004, 5026, 5111, 5331, 5356, 5374, 5435, 5460, 5479, 5500, 5577, 5594, 5664], '(552)': [427], 'Google': [428, 441, 510, 528, 549, 572, 600, 618, 669, 689, 708, 730, 755, 785, 833, 857, 884, 918, 947, 970, 989, 1010, 1038, 1064, 1097, 1114, 1147, 1167, 1186, 1208, 1287, 1307, 1328, 1372, 1411, 1436, 1464, 1486, 1504, 1542, 1572, 1605, 1632, 1654, 1690, 1748, 1786, 1814, 1855, 1913, 1936, 1995, 2044, 2074, 2211, 2252, 2279, 2358, 2416, 2469, 2490, 2552, 2718, 2760, 2821, 3027, 3212, 3362, 3388, 3673, 3701, 3884, 3906, 4009, 4146, 4165, 4187, 4208, 4231, 4261, 4327, 4348, 4371, 4401, 4449, 4507, 4565, 4594, 4809, 4898, 4921, 4946, 4987, 5006, 5028, 5113, 5333, 5358, 5376, 5437, 5462, 5481, 5502, 5579, 5596, 5666], 'Scholar,': [429, 511, 529, 550, 601, 670, 690, 709, 731, 756, 919, 948, 971, 990, 1011, 1065, 1098, 1148, 1168, 1187, 1288, 1308, 1412, 1437, 1465, 1487, 1543, 2045, 2470, 3363, 3674, 4147, 4166, 4188, 4209, 4232, 4328, 4349, 4372, 4899, 4922, 4988, 5007, 5334, 5359, 5438, 5463, 5482], '2Luhrmann': [430], 'Mol.': [432, 564, 700, 742, 776, 962, 981, 1002, 1178, 1359, 1405, 1681, 1739, 1805, 1846, 1904, 1986, 2031, 2065, 2243, 2460, 2751, 2812, 3664, 4000, 4157, 4436, 4498, 4552, 4585, 4998], 'Rep.': [434], '1990;': [435], '14:': [436, 613], '183-192Crossref': [437], '(25)': [440], 'Scholar).': [442, 573, 786, 885, 1115, 1209, 1329, 1373, 1505, 1691, 1749, 1856, 1914, 1996, 2075, 2212, 2359, 2491, 2553, 2719, 2761, 2822, 3028, 3389, 3907, 4262, 4402, 4450, 4508, 4595, 4810, 4947, 5377, 5503, 5597], 'form': [446], 'head-to-tail': [447], 'structure': [451, 5310, 5379], 'around': [452], 'site': [455], 'snRNA,': [458], 'which': [459, 1047, 1951, 2013, 2955, 3179, 4517, 4866, 5304, 5401], 'bound': [461, 1867, 2649, 3613, 3631, 3800, 3816, 3836, 5248], 'center': [464], 'at': [469, 1947, 2637, 2858, 3298, 5187], 'least': [470, 1948, 3299, 5188], 'SmG': [471], 'SmB': [473, 2850, 3820], 'directly': [474], 'contacting': [475], 'RNA': [477], '(3Kambach': [478], 'C.': [479, 1081, 1489, 3343, 5314, 5342, 5446], 'Walke': [480], 'S.': [481, 517, 541, 735, 737, 760, 764, 939, 992, 1013, 1067, 1071, 1320, 1352, 1354, 1400, 1527, 1555, 1557, 1587, 1591, 1597, 1639, 1665, 1669, 1723, 1727, 1830, 1834, 1888, 1892, 1970, 1974, 2024, 2026, 2049, 2053, 2197, 2227, 2231, 2398, 2402, 2408, 2444, 2448, 2482, 2735, 2739, 2796, 2800, 3198, 3648, 3652, 3678, 3898, 3984, 3988, 4429, 4431, 4482, 4486, 4545, 4547, 4569, 4573, 4786, 5649, 5651], 'Young': [482], 'Avis': [484], 'J.M.': [485, 925, 927], 'de': [486, 5092, 5558], 'la': [487], 'Fortelle': [488], 'E.': [489, 952, 3369, 5418], 'Raker': [490, 514, 693, 1171, 4150, 4991], 'V.A.': [491, 515, 587], 'Li': [494, 5339, 5443], 'J.': [495, 521, 563, 593, 611, 771, 848, 868, 875, 901, 904, 977, 1024, 1054, 1102, 1293, 1441, 1493, 1497, 1528, 1558, 1618, 1640, 1676, 1734, 1841, 1899, 1981, 2060, 2238, 2270, 2344, 2455, 2543, 2709, 2746, 2807, 3018, 3659, 3676, 3687, 3870, 3995, 4194, 4199, 4213, 4247, 4313, 4334, 4339, 4353, 4387, 4493, 4580, 4784, 4795, 4912, 4930, 4937, 5089, 5099, 5338, 5442, 5465, 5486, 5555, 5565, 5652], 'Nagai': [496], 'K.': [497, 1447, 1613, 1926, 3345, 4236, 4376, 5316], 'Cell.': [498, 657, 677, 718, 743, 777, 821, 1135, 1155, 1196, 1275, 1360, 1452, 1682, 1740, 1774, 1806, 1847, 1905, 1987, 2032, 2066, 2244, 2461, 2752, 2813, 3378, 3665, 4001, 4134, 4175, 4437, 4499, 4553, 4586, 4886, 4975, 5016, 5364, 5427], '1999;': [499, 702, 851, 964, 1180, 1322, 1430, 1531, 1808, 2484, 3351, 3900, 4159, 4915, 5000, 5322], '96:': [500, 1323, 2485, 3901], '375-387Abstract': [501], 'Full': [502, 504, 661, 663, 681, 683, 722, 724, 747, 749, 825, 827, 910, 912, 1030, 1032, 1091, 1108, 1139, 1141, 1159, 1161, 1200, 1202, 1279, 1281, 1299, 1301, 1364, 1366, 1456, 1458, 1534, 1536, 1564, 1566, 1624, 1626, 1646, 1648, 1778, 1780, 2036, 2038, 2350, 2352, 3354, 3356, 3382, 3693, 3695, 3876, 3878, 4138, 4140, 4179, 4181, 4223, 4225, 4253, 4255, 4319, 4321, 4363, 4365, 4393, 4395, 4441, 4443, 4557, 4559, 4801, 4803, 4890, 4892, 4979, 4981, 5020, 5022, 5105, 5107, 5325, 5327, 5368, 5370, 5431, 5571, 5573, 5658, 5660], 'Text': [503, 505, 662, 664, 682, 684, 723, 725, 748, 750, 826, 828, 911, 913, 1031, 1033, 1092, 1109, 1140, 1142, 1160, 1162, 1201, 1203, 1280, 1282, 1300, 1302, 1365, 1367, 1457, 1459, 1535, 1537, 1565, 1567, 1625, 1627, 1647, 1649, 1779, 1781, 2037, 2039, 2351, 2353, 3355, 3357, 3383, 3694, 3696, 3877, 3879, 4139, 4141, 4180, 4182, 4224, 4226, 4254, 4256, 4320, 4322, 4364, 4366, 4394, 4396, 4442, 4444, 4558, 4560, 4802, 4804, 4891, 4893, 4980, 4982, 5021, 5023, 5106, 5108, 5326, 5328, 5369, 5371, 5432, 5572, 5574, 5659, 5661], 'PDF': [506, 665, 685, 726, 751, 829, 914, 1034, 1093, 1110, 1143, 1163, 1204, 1283, 1303, 1368, 1460, 1538, 1568, 1628, 1650, 1782, 2040, 2354, 3358, 3384, 3697, 3880, 4142, 4183, 4227, 4257, 4323, 4367, 4397, 4445, 4561, 4805, 4894, 4983, 5024, 5109, 5329, 5372, 5433, 5575, 5662], '(364)': [509], '4Urlaub': [512], 'H.': [513, 533, 1416, 1418, 1765, 2267, 5087, 5553], 'Kostka': [516], 'EMBO': [520, 592, 610, 1496], '20:': [523], '187-196Crossref': [524], '(107)': [527, 548], '5Achsel': [530], 'T.': [531, 2195, 2201, 3196, 3202], 'Stark': [532], 'Proc.': [536, 934, 1315, 1592, 2403, 2477, 3893], 'Natl.': [537, 935, 1316, 1593, 2404, 2478, 3894], 'Acad.': [538, 936, 1317, 1594, 2405, 2479, 3895], 'Sci.': [539, 937, 1318, 1595, 2406, 2480, 3350, 3896, 5321], 'U.': [540, 652, 672, 698, 816, 938, 1000, 1130, 1150, 1176, 1270, 1319, 1596, 2407, 2481, 3897, 4129, 4155, 4240, 4380, 4881, 4970, 4996], 'A.': [542, 739, 762, 843, 870, 940, 1321, 1356, 1547, 1598, 1637, 1667, 1725, 1832, 1890, 1972, 2028, 2051, 2193, 2229, 2409, 2446, 2483, 2737, 2798, 3194, 3650, 3899, 3986, 4433, 4484, 4549, 4571, 4907, 4932, 5091, 5467, 5488, 5557, 5641], '98:': [544], '3685-3689Crossref': [545], '6Collins': [551], 'B.M.': [552], 'Harrop': [553], 'S.J.': [554], 'Kornfeld': [555], 'G.D.': [556], 'Dawes': [557], 'I.W.': [558], 'Curmi': [559], 'P.M.': [560], 'Mabbutt': [561], 'B.C.': [562], '309:': [567], '915-923Crossref': [568], '(81)': [571], 'Although': [574, 3249, 3908], 'can': [577, 5515, 5630], 'spontaneously': [579], 'from': [580, 2145, 2511, 2567, 3120, 3172, 3408, 3420, 3532, 3973, 4068], 'purified,': [581], 'concentrated': [582], 'vitro': [585, 2286, 2333, 2373, 2580, 3033, 3580, 3749, 4753, 5637], '(7Raker': [586], 'Plessel': [588], 'G.': [589, 656, 676, 717, 741, 769, 775, 820, 847, 874, 903, 1023, 1134, 1154, 1195, 1274, 1292, 1314, 1358, 1583, 1609, 1674, 1680, 1732, 1738, 1839, 1845, 1897, 1903, 1979, 1985, 2030, 2058, 2064, 2236, 2242, 2269, 2343, 2394, 2453, 2459, 2476, 2542, 2708, 2744, 2750, 2805, 2811, 3017, 3657, 3663, 3869, 3892, 3993, 3999, 4133, 4174, 4198, 4217, 4312, 4338, 4357, 4435, 4491, 4497, 4551, 4578, 4584, 4885, 4911, 4936, 4974, 5015], '1996;': [594, 2205, 3206, 5352, 5365, 5456, 5475, 5496], '15:': [595], '2256-2269Crossref': [596], '(195)': [599], '8Segault': [602], 'V.': [603, 694, 1172, 4151, 4992], 'Will': [604], 'Sproat': [606], 'B.S.': [607], '1995;': [612, 1088, 2273, 3379, 5428], '4010-4021Crossref': [614], '(65)': [617], 'Scholar),': [619, 834, 858, 1606, 1633, 3702, 5029, 5580, 5667], 'it': [620, 3258, 3909, 4073, 4679, 4707, 4739, 4758, 5059, 5171, 5264, 5514, 5519, 5686], 'becoming': [622], 'increasingly': [623], 'clear': [624, 5266], 'vivo': [628, 1126], 'pathway': [631], 'involves': [635], 'two': [636, 5189], 'complexes,': [638], 'neuron': [643], '(9Liu': [649, 813, 1127, 1267, 4878], 'Q.': [650, 674, 814, 1128, 1152, 1268, 2706, 4131, 4879, 4972], 'Fischer': [651, 697, 815, 999, 1129, 1175, 1269, 4154, 4239, 4379, 4880, 4995], 'Wang': [653, 817, 1131, 1271, 4882], 'F.': [654, 818, 1132, 1272, 1922, 4242, 4382, 4883, 5094, 5560], 'Dreyfuss': [655, 675, 716, 740, 774, 819, 846, 873, 902, 1022, 1133, 1153, 1194, 1273, 1291, 1313, 1357, 1679, 1737, 1844, 1902, 1984, 2029, 2063, 2241, 2268, 2342, 2458, 2475, 2541, 2707, 2749, 2810, 3016, 3662, 3868, 3891, 3998, 4132, 4173, 4197, 4216, 4311, 4337, 4356, 4434, 4496, 4550, 4583, 4884, 4910, 4935, 4973, 5014], '1997;': [658, 678, 822, 941, 1058, 1105, 1136, 1156, 1276, 1498, 2712, 4135, 4887, 4976], '90:': [659, 679, 823, 1137, 1157, 1277, 4136, 4888, 4977], '1013-1021Abstract': [660, 824, 1138, 1278, 4889], '(541)': [668, 832, 1146, 1286, 4897], '10Fischer': [671, 1149], 'Liu': [673, 1151, 1762, 2705, 4130, 4971], '1023-1029Abstract': [680, 1158, 4137, 4978], '(557)': [688, 1166, 4145, 4986], '11Buhler': [691, 1169, 4148, 4989], 'D.': [692, 994, 1170, 1414, 1767, 4149, 4990], 'Hum.': [699, 961, 980, 1001, 1103, 1177, 4156, 4997], 'Genet.': [701, 963, 982, 1003, 1104, 1179, 4158, 4999], '8:': [703, 965, 1181, 4160, 5001], '2351-2357Crossref': [704, 1182, 4161, 5002], '(221)': [707, 1185, 4164, 5005], '12Pellizzoni': [710, 1188, 4167, 5008], 'L.': [711, 839, 864, 1017, 1021, 1069, 1077, 1189, 1310, 1615, 1802, 2199, 2472, 2704, 3200, 3888, 4168, 4190, 4211, 4330, 4351, 4903, 4926, 5009, 5096, 5562], 'Kataoka': [712, 1190, 2701, 4169, 5010], 'N.': [713, 973, 1191, 2702, 4170, 5011], 'Charroux': [714, 1014, 1192, 1311, 2473, 3889, 4171, 4191, 4214, 4331, 4354, 5012], 'B.': [715, 837, 862, 921, 998, 1015, 1079, 1193, 1312, 1491, 1761, 2474, 3890, 4172, 4192, 4215, 4332, 4355, 4901, 4924, 5013], '1998;': [719, 1197, 1407, 1480, 1599, 1621, 1775, 1930, 2410, 4176, 5017], '95:': [720, 1198, 1600, 2411, 4177, 5018], '615-624Abstract': [721, 1199, 4178, 5019], '(466)': [729, 1207, 4186, 5027], '13Friesen': [732], 'W.J.': [733, 758, 1290, 1350, 1663, 1721, 1828, 1886, 1968, 2022, 2047, 2225, 2341, 2442, 2733, 2794, 3646, 3867, 3982, 4310, 4427, 4480, 4543, 4567], 'Massenet': [734, 763, 1351, 1668, 1726, 1833, 1891, 1973, 2023, 2052, 2230, 2447, 2738, 2799, 3651, 3987, 4428, 4485, 4544, 4572], 'Paushkin': [736, 759, 1353, 1664, 1722, 1829, 1887, 1969, 2025, 2048, 2226, 2443, 2734, 2795, 3647, 3983, 4430, 4481, 4546, 4568], 'Wyce': [738, 761, 1355, 1666, 1724, 1831, 1889, 1971, 2027, 2050, 2228, 2445, 2736, 2797, 3649, 3985, 4432, 4483, 4548, 4570], '7:': [745, 1362, 2034, 4439, 4555], '1111-1117Abstract': [746, 1363, 2035, 4440, 4556], '(296)': [754, 1371, 2043, 4448, 4564], '14Friesen': [757, 2046], 'Pesiridis': [765, 1670, 1728, 1835, 1893, 1975, 2054, 2232, 2449, 2740, 2801, 3653, 3989, 4487, 4574], 'G.S.': [766, 1671, 1729, 1836, 1894, 1976, 2055, 2233, 2450, 2741, 2802, 3654, 3990, 4488, 4575, 5586], 'Van': [767, 1672, 1730, 1837, 1895, 1977, 2056, 2234, 2451, 2742, 2803, 3655, 3991, 4489, 4576], 'Duyne': [768, 1673, 1731, 1838, 1896, 1978, 2057, 2235, 2452, 2743, 2804, 3656, 3992, 4490, 4577], 'Rappsilber': [770, 1675, 1733, 1840, 1898, 1980, 2059, 2237, 2454, 2745, 2806, 3658, 3994, 4193, 4333, 4492, 4579], 'Mann': [772, 844, 871, 1677, 1735, 1842, 1900, 1982, 2061, 2202, 2239, 2456, 2747, 2808, 3203, 3660, 3996, 4195, 4335, 4494, 4581, 4908, 4933], 'M.': [773, 845, 872, 933, 996, 1085, 1451, 1495, 1579, 1678, 1736, 1843, 1901, 1924, 1983, 2062, 2191, 2203, 2240, 2390, 2457, 2748, 2809, 3192, 3204, 3661, 3997, 4196, 4336, 4495, 4582, 4909, 4934], '21:': [780, 1685, 1743, 1850, 1908, 1990, 2069, 2247, 2464, 2755, 2816, 3668, 4004, 4502, 4589], '8289-8300Crossref': [781, 1686, 1744, 1851, 1909, 1991, 2070, 2248, 2465, 2756, 2817, 3669, 4005, 4503, 4590], '(319)': [784, 1689, 1747, 1854, 1912, 1994, 2073, 2251, 2468, 2759, 2820, 3672, 4008, 4506, 4593], 'SMN,': [787, 810, 4867], 'spinal': [789, 1050], 'muscular': [790, 1051], 'atrophy': [791, 1052], 'disease': [792], 'gene': [793], 'product,': [794], 'present': [796, 1699], 'metazoan': [799], 'cells': [800, 899, 2676, 3974], 'as': [801, 1576, 1821, 2438, 2536, 2694, 2729, 2790, 3157, 3159, 3394, 3475, 3604, 3642, 3788, 3978, 4044, 4646, 4701, 4953, 5032, 5034, 5527, 5529, 5618, 5620], 'which,': [805, 2166], 'oligomeric': [809], 'includes': [811], 'Gemin2': [812], 'Gemin3': [835], '(15Charroux': [836], 'Pellizzoni': [838, 863, 1020, 4902, 4925], 'Perkinson': [840, 865, 1018, 4904, 4927], 'R.A.': [841, 866, 1019, 1585, 2396, 4905, 4928], 'Shevchenko': [842, 869, 2192, 3193, 4906, 4931], '147:': [852, 4916], '1181-1194Crossref': [853, 4917], '(226)': [856, 4920], 'Gemin4': [860, 4870], '(16Charroux': [861], 'Yong': [867, 4929], '2000;': [878, 983, 1004, 1027, 1296, 1643, 2347, 3873, 4316, 4940, 5102, 5568], '148:': [879, 4941], '1177-1186Crossref': [880, 4942], '(204)': [883, 4945], 'Reduced': [886], 'levels': [887], 'loss-of-function': [890], 'mutations': [891], 'affect': [894], 'growth': [896], '(17Wang': [900], 'Chem.': [906, 1026, 1295, 1530, 1560, 1620, 1642, 2346, 3689, 3872, 4249, 4315, 4389, 4797, 5101, 5567, 5654], '276:': [908, 1562, 3691, 4251, 4391, 4799, 5656], '9599-9605Abstract': [909], '(54)': [917], '18Schrank': [920], 'Gotz': [922], 'Gunnersen': [924], 'Ure': [926], 'Toyka': [928], 'K.V.': [929], 'Smith': [930, 5347, 5362, 5451], 'A.G.': [931, 3375, 5424], 'Sendtner': [932], '94:': [942], '9920-9925Crossref': [943], '(553)': [946], '19Miguel-Aliaga': [949], 'I.': [950, 5336, 5440], 'Culetto': [951], 'Walker': [953], 'D.S.': [954, 3686, 4794], 'Baylis': [955], 'H.A.': [956], 'Sattelle': [957], 'D.B.': [958], 'Davies': [959, 978], 'K.E.': [960, 979], '2133-2143Crossref': [966], '(104)': [969], '20Owen': [972], 'Doe': [974], 'Mellor': [976], '9:': [984, 1005], '675-684Crossref': [985], '(55)': [988], '21Hannus': [991], 'Buhler': [993], 'Romano': [995], 'Seraphin': [997], '663-674Crossref': [1006], '(63)': [1009], '22Paushkin': [1012], 'Abel': [1016], '275:': [1028, 1297, 1644, 2348, 3874, 4317, 5103, 5569], '23841-23846Abstract': [1029], '(59)': [1037], 'Scholar)': [1039, 1573, 1787, 1815, 1937, 2253, 2280, 2417, 3213, 4010], 'cause': [1041], 'degeneration': [1043], 'neurons,': [1046], 'results': [1048, 3707, 4102], '(23Melki': [1053], 'Neurol.': [1057], '10:': [1059], '381-385Crossref': [1060], '(83)': [1063], '24Lefebvre': [1066], 'Burglen': [1068], 'Reboullet': [1070], 'Clermont': [1072], 'O.': [1073, 5346, 5450], 'Burlet': [1074], 'P.': [1075, 1083, 1581, 2392], 'Viollet': [1076], 'Benichou': [1078], 'Cruaud': [1080], 'Millasseau': [1082], 'Zeviani': [1084], 'et': [1086], 'al.Cell.': [1087], '80:': [1089], '155-165Abstract': [1090], '(3049)': [1096], '25Burghes': [1099], 'A.H.': [1100], 'Am.': [1101], '61:': [1106, 1408], '9-15Abstract': [1107], '(237)': [1113, 1541], 'critical': [1120, 5176], 'presence': [1211, 5245], 'Gemin3,': [1213, 4868], 'DEAD': [1215], 'box': [1216], 'putative': [1218], 'RNA-dependent': [1219], 'ATPase,': [1220], 'strongly': [1221, 4103], 'suggests': [1222, 5116], 'plays': [1227, 3961], 'active': [1229], '(ATP-dependent)': [1230], 'role': [1231, 3963, 4601, 5123, 5690], 'assembly.': [1234, 5129], 'Direct': [1235], 'binding': [1236, 2603, 2647, 3626, 3847, 3859, 5227], '(RG)': [1244], 'three': [1247, 4694, 4737, 5541], '(SmB,': [1252], 'SmD1,': [1253, 3754, 5550], 'SmD3)': [1255], 'appears': [1256, 5181, 5217], '26Friesen': [1289, 3866], '26370-26375Abstract': [1298, 2349, 3875, 4318], '(119)': [1306, 2357, 3883, 4326], '27Pellizzoni': [1309, 2471, 3887], '11167-11172Crossref': [1324, 2486, 3902], '(220)': [1327, 2489, 3905], 'Importantly,': [1330, 4061, 4848], 'preferentially': [1333], 'RG': [1336, 1660, 1862, 1877, 2975, 4298, 4420, 4523, 5162], 'after': [1338], 'been': [1341, 1791, 2337, 2888, 2904, 4721], 'post-translationally': [1342], 'modified': [1343, 2681, 5159], 'contain': [1345, 1953, 2153, 3228, 5548], '(sDMAs)': [1348], '(13Friesen': [1349, 2021, 4426, 4542], 'Protein': [1374, 3325], 'methyltransferases': [1376], '(PRMTs)': [1377], 'produce': [1378, 2255, 2282, 5279], 'either': [1379], 'asymmetric': [1380], '(aDMA)': [1382], '(type': [1383, 1388], 'I': [1384], 'enzyme)': [1385, 1390], 'sDMA': [1387, 1998, 5285], 'II': [1389, 1508], 'diverse': [1395, 5297], '(28Gary': [1397], 'J.D.': [1398], 'Clarke': [1399, 1556, 1638, 5650], 'Prog.': [1401], 'Nucleic': [1402], 'Acid': [1403], 'Res.': [1404], '65-131Crossref': [1409], '29Chen': [1413], 'Ma': [1415], 'Hong': [1417], 'Koh': [1419], 'S.S.': [1420], 'Huang': [1421], 'S.M.': [1422], 'Schurter': [1423, 1444], 'B.T.': [1424, 1445], 'Aswad': [1425], 'D.W.': [1426], 'Stallcup': [1427], 'M.R.': [1428], 'Science.': [1429, 5589], '284:': [1431], '2174-2177Crossref': [1432], '(1006)': [1435], '30Mowen': [1438], 'K.A.': [1439], 'Tang': [1440], 'Zhu': [1442], 'W.': [1443, 1521, 1611], 'Shuai': [1446], 'Herschman': [1448], 'H.R.': [1449], 'David': [1450], '104:': [1454], '731-741Abstract': [1455], '(397)': [1463], '31Shen': [1466], 'E.C.': [1467], 'Henry': [1468], 'M.F.': [1469], 'Weiss': [1470], 'V.H.': [1471], 'Valentini': [1472], 'S.R.': [1473, 3377, 5426], 'Silver': [1474], 'P.A.': [1475], 'Lee': [1476, 1548, 3368, 5417, 5642], 'M.S.': [1477], 'Genes': [1478], 'Dev.': [1479], '12:': [1481], '679-691Crossref': [1482], '(252)': [1485], '32Abramovich': [1488], 'Yakobson': [1490], 'Chebath': [1492], 'Revel': [1494], '16:': [1499], '260-266Crossref': [1500], '(154)': [1503], 'type': [1507], 'PRMT': [1509], 'Janus': [1510], 'kinase-binding': [1511], '1': [1513, 2600, 2622, 2644, 3096], '(33Pollack': [1516], 'B.P.': [1517], 'Kotenko': [1518], 'S.V.': [1519], 'He': [1520], 'Izotova': [1522], 'L.S.': [1523], 'Barnoski': [1524], 'B.L.': [1525], 'Pestka': [1526, 1554, 5648], '274:': [1532], '31531-31542Abstract': [1533], '34Branscombe': [1544], 'T.L.': [1545, 5639], 'Frankel': [1546, 5640], 'J.-H.': [1549, 5643], 'Cook': [1550, 5644], 'J.R.': [1551, 5645], 'Yang': [1552, 1580, 2391, 5646], 'Z-h.': [1553, 5647], '32971-32976Abstract': [1563, 5657], '(303)': [1571, 5665], '(also': [1574], 'skb1Hs': [1577], '(35Gilbreth': [1578, 2389], 'Bartholomeusz': [1582, 2393], 'Pimental': [1584, 2395], 'Kansra': [1586, 2397], 'Gadiraju': [1588, 2399], 'Marcus': [1590, 2401], '14781-14786Crossref': [1601, 2412], '(61)': [1604, 2415], 'IBP72': [1607], '(36Krapivinsky': [1608], 'Pu': [1610], 'Wickman': [1612], 'Krapivinsky': [1614, 1799, 1801], 'Clapham': [1616, 1803], 'D.E.': [1617, 1804, 3367, 5416], '273:': [1622], '10811-10814Abstract': [1623], '(58)': [1631], 'PRMT5': [1635], '(37Frankel': [1636], '32974-32982Abstract': [1645], '(96)': [1653], 'Scholar))': [1655], 'symmetrically': [1656, 2969, 5631, 5675], 'dimethylates': [1657], '(14Friesen': [1662, 1720, 1827, 1885, 1967, 2224, 2441, 2732, 2793, 3645, 3981, 4479], 'shown': [1695, 1792, 2951, 3863, 4406, 5082], 'context': [1705], '20': [1711, 3534], 'S': [1712, 3535], 'also': [1715, 1941, 1952, 3552, 3824, 4822, 4840, 5040, 5142, 5241, 5507], 'PICln': [1750, 1915], 'was': [1751, 2143, 2217, 2363, 2418, 2495, 2692, 2780, 2831, 3009, 3040, 3055, 3170, 3225, 3442, 3460, 3844, 4042], 'initially': [1752], 'thought': [1753], 'ion': [1757], 'channel': [1758], 'regulator': [1759], '(38Santoro': [1760], 'D.T.': [1763], 'Yao': [1764], 'Bartsch': [1766], 'Kandel': [1768], 'E.R.': [1769], 'Siegelbaum': [1770], 'S.A.': [1771], 'Tibbs': [1772], 'G.R.': [1773], '93:': [1776], '717-729Abstract': [1777], '(585)': [1785], 'but': [1788, 3080, 3633, 3823, 4049, 4745], 'has': [1790], '(39Pu': [1797], 'W.T.': [1798], 'G.B.': [1800], '19:': [1809], '4113-4120Crossref': [1810], '(85)': [1813], 'A': [1857, 3270], 'fraction': [1858, 2723], 'cytoplasmic': [1861, 3122, 3440], 'domain-containing': [1863], 'vivo.': [1872], 'domains,': [1878], 'whereas': [1879], 'domain': [1884, 2308, 2504, 3769, 3776, 3815, 5163], 'phosphoprotein': [1918], '(40Sanchez-Olea': [1919], 'Emma': [1921], 'Coghlan': [1923], 'Strange': [1925], 'Biochim.': [1927], 'Biophys.': [1928], 'Acta.': [1929], '1381:': [1931], '49-60Crossref': [1932], '(20)': [1935], 'found': [1940, 2151, 3226], 'smaller': [1943], 'complexes': [1944, 5192], '(4–6': [1945], 'S),': [1946], 'some': [1949], 'regulate': [1960], 'association': [1963, 3432], 'After': [1997, 2912, 3131, 3502, 3610, 3797], 'by': [2000, 2183, 2314, 2497, 2559, 2653, 2657, 2924, 3061, 3138, 3188, 3266, 3424, 3455, 3509, 3617, 3621, 3804, 3808, 3925, 3949, 4071, 4471, 4703, 5052, 5077, 5237], 'become': [2005], 'high': [2006], 'affinity': [2007, 3827], 'likely': [2014, 4709, 4760, 5306], 'completes': [2015], 'their': [2016, 4844, 5046], 'MEP50.': [2088, 3468, 4686], 'MEP50,': [2092, 4640, 5605], 'protein,': [2097, 2963, 4645], 'activity.': [2109, 3966, 4666, 4819, 5221], 'surface': [2116], 'area': [2117], 'An': [2136, 3217], 'expressed': [2137, 3218, 3549], 'sequence': [2138, 3219, 5302], 'tag': [2139, 3220], '(GenBankTM': [2140, 3221], 'accession': [2141, 2944, 3222], 'numberAL533305)': [2142], 'obtained': [2144, 2182, 2558, 3187], 'Invitrogen': [2146], '(clone': [2147], 'Id:': [2148], 'CS0DN003YE12)': [2149], 'open': [2155, 2214, 3230], 'reading': [2156, 2215, 3231], 'frame': [2157, 2216, 3232], '(with': [2158, 3233], 'in-frame': [2160], 'stop': [2161, 3235], 'codons': [2162, 3236], 'upstream': [2163, 3237], 'downstream),': [2165], 'upon': [2167], 'conceptual': [2168], 'translation,': [2169], 'contained': [2170], 'amino': [2171], 'acid': [2172, 2508, 3003], 'sequences': [2173, 2181, 3246], 'exactly': [2175], 'matched': [2176, 3241], 'peptide': [2180, 3177, 3245], '(nano-ES': [2188], 'MS/MS)': [2189], '(41Wilm': [2190, 3191], 'Houthaeve': [2194, 3195], 'Breit': [2196, 3197], 'Schweigerer': [2198, 3199], 'Fotsis': [2200, 3201], 'Nature.': [2204, 3205, 5474, 5495], '379:': [2206, 3207, 5476, 5497], '466-469Crossref': [2207, 3208], '(1507)': [2210, 3211], 'This': [2213, 3167, 3274, 3293, 4596, 4858], 'PCR': [2218, 2364, 2419], 'amplified': [2219, 2365, 2420], 'cloned': [2221], 'pGV67': [2223, 2424, 2512], '(to': [2254, 2281], 'pGV67MEP50)': [2256], 'production': [2258, 2287, 2335, 2533], 'GST-MEP50': [2260, 2299, 2306, 2895, 3766, 3780, 3811, 3813, 3833, 4076], 'fusion': [2261, 2384, 2427, 2595, 2660], 'mycpcDNA3': [2265], '(42Siomi': [2266], '129:': [2274], '551-560Crossref': [2275], '(444)': [2278], 'mycMEP50pcDNA3)': [2283], 'Myc-tagged': [2289, 3550], '(myc-MEP50).': [2291], 'Similarly,': [2292], 'constructs': [2293, 2329], 'expression': [2296], 'N': [2300, 3781, 3834], 'terminus': [2301, 3782, 3835], '(amino': [2302, 2309, 2507, 3002], 'acids': [2303, 2310], '1–75)': [2304], '76–342)': [2311], 'were': [2312, 2436, 2534, 2557, 2586, 2651, 2662, 2677, 2727, 2767, 2865, 2916, 2928, 2993, 3136, 3186, 3400, 3451, 3489, 3507, 3526, 3588, 3615, 3761, 3802, 3971, 4027], 'made': [2313], 'inserting': [2315], 'appropriate': [2317], 'cDNA': [2319, 2362, 2388], 'fragments': [2320], 'pGEX6p2': [2322], '(Amersham': [2323, 2379, 2590, 2667, 2838, 2933], 'Biosciences,': [2324, 2380, 2591, 2668, 2839, 2934], 'Inc.).': [2325], 'All': [2326], 'used': [2330, 2763, 2783, 4012, 4029, 4043], 'previously': [2338, 2440, 2538, 2696, 2731, 2792, 3644, 3980], '(26Friesen': [2340, 4309], 'subcloned': [2367, 2422], 'pET28a(+)': [2369], '(Novagen)': [2370], 'production,': [2375, 2528], 'pGEX5x': [2378], 'Inc.)': [2381, 2592, 2669], 'GST-pICln': [2383], 'production.': [2386, 2429], 'GST-JBP1': [2426], 'recombinant': [2431, 2786, 2846, 2997, 3413, 4016], 'GST-D3': [2433], 'His-SmB': [2435, 4020], 'produced': [2437, 2987, 3034, 3581, 3750], 'Anti-JBP1': [2492], 'antibody': [2493, 3066, 3103, 3530, 4633], '6G8': [2494, 3044, 3064, 3099], 'prepared': [2496, 2693, 2781, 3443], 'immunizing': [2498, 2560], 'Balb/C': [2499, 2561], 'mice': [2500, 2562, 3399, 3410], 'C-terminal': [2503], '284–637)': [2509], 'purified': [2510, 2566, 2663, 2827, 3972], 'on': [2513, 2569, 2664, 3057, 3323, 3446, 4411, 5714], 'glutathione-Sepharose': [2514, 2570, 2589, 2665], 'cleaved': [2516, 2572], 'off': [2517, 2573], 'beads': [2519, 2575], 'TEV': [2521, 2577], '(tobacco': [2522], 'etch': [2523], 'virus)': [2524], 'protease': [2525, 2628], '(Invitrogen).': [2526], 'Hybridoma': [2527], 'screening,': [2529], 'ascites': [2531, 3045, 3048], 'fluid': [2532, 3049], 'performed': [2535, 3117], '(43Choi': [2539, 3014], 'Y.D.': [2540, 3015], '1984;': [2546, 3021], '99:': [2547, 3022], '1997-2004Crossref': [2548, 3023], '(146)': [2551, 3026], 'Polysera': [2554], 'against': [2555, 2990, 4635], 'pGV67MEP50': [2568], 'protease.': [2578], 'In': [2579, 3579, 3639, 4081, 5056, 5167], 'translated': [2581], '[35S]methionine-labeled': [2582], '(8': [2584], 'μl)': [2585, 2830], 'incubated': [2587, 2832, 3041, 3590, 3763], 'immobilized': [2593, 2894, 2910, 3043, 3592, 4075, 4088], 'GST': [2594, 2659, 3593, 3608, 3792, 3855, 4089], '(2–3': [2597], 'μg)': [2598], 'ml': [2601, 2624, 2645], 'buffer': [2604, 2921], 'mm': [2606, 2611, 2614], 'Tris,': [2607], 'pH': [2608], '7.5,': [2609], '200': [2610], 'NaCl,': [2612], '0.2': [2613], 'EDTA,': [2615], '0.05%': [2616], 'Nonidet': [2617], 'P-40,': [2618], '2': [2619, 2834, 3146, 3215, 3269, 3338], 'mmdithiothreitol,': [2620], 'tablet/50': [2623], 'Complete': [2626], 'EDTA-free': [2627], 'inhibitor': [2629], 'mixture': [2630], '(Roche': [2631], 'Molecular': [2632], 'Biochemicals))': [2633], '1–2': [2635], 'h': [2636], '4': [2638], '°C.': [2639], 'Following': [2640], 'five': [2641, 3176], 'washes': [2642], 'buffer,': [2648], 'separated': [2652], 'SDS-PAGE': [2654, 3058, 3139, 3267, 3510, 3618, 3805], 'detected': [2656, 3083, 3412, 3527, 4702], 'fluorography.': [2658, 3062], '4B': [2666], 'according': [2670], "manufacturer's": [2673], 'recommendation.': [2674], 'HeLa': [2675, 3075, 3121, 3421, 3438], 'cultured': [2678], "Dulbecco's": [2680], "Eagle's": [2682], 'medium': [2683], 'supplemented': [2684, 2866], '10%': [2686], 'fetal': [2687], 'bovine': [2688], 'serum.': [2689], 'Cytoplasmic': [2690], 'extract': [2691, 3076, 3123, 3423, 3441], '(44Siomi': [2697], 'M.C.': [2698], 'Eder': [2699], 'P.S.': [2700], 'Wan': [2703], '138:': [2713], '1181-1192Crossref': [2714], '(206)': [2717], 'Sucrose': [2720], 'gradient': [2721], 'centrifugation,': [2722], 'collection,': [2724], 'immunoprecipitation': [2726], 'done': [2728], 'Antibodies': [2762], 'experiments': [2766], 'anti-pICln': [2768, 3128, 3151], '(Transduction': [2769], 'Laboratories),': [2770], 'anti-Myc': [2771], '(9E10),': [2772], 'anti-JBP1': [2773, 3125, 3149, 3494, 3529, 4690], '(6G8),': [2774], 'anti-MEP50': [2776, 2871, 2884, 2900, 4066, 4085, 4099, 5205], 'polysera.': [2777], 'methylate': [2785, 4014, 4827], 'Approximately': [2823], '100': [2824], 'ng': [2825], '(4': [2829], 'μl': [2835, 2842, 2854, 2869, 2874, 2882, 2898], 'adenosyl-l-[methyl-3H]methionine': [2837], 'Inc.),': [2840, 2935], '3': [2841, 3520], '(600': [2843], 'ng)': [2844], 'GST-SmD3': [2847, 4022], 'His-tagged': [2849], '(His-SmB),': [2851], '21': [2853], 'phosphate-buffered': [2856], 'saline': [2857], '30': [2859], '°C': [2860], '45': [2862], 'min.': [2863], 'Reactions': [2864], '5': [2868, 2873, 2881, 2897], 'serum,': [2872], '(NMS),': [2879], 'had': [2887, 2903, 3825], 'pre-incubated': [2889, 2905], '1.5': [2891, 2907], 'μg': [2892, 2908], 'GST.': [2911], 'methylation,': [2913], 'mixtures': [2915], 'boiled': [2917], 'SDS': [2919], 'sample': [2920], 'resolved': [2923, 3056, 3137, 3454, 3508, 3616, 3803], 'SDS-PAGE.': [2925], 'gels': [2927], 'then': [2929, 4028], 'treated': [2930], 'Amplify': [2932], 'dried,': [2936], 'exposed': [2938], 'film.': [2940], 'GenBankTM': [2943], 'number': [2945, 3223], 'AF478464.': [2947], 'cytoplasm': [2967], 'dimethylate': [2970, 5632, 5676], 'To': [2981, 3029, 3108, 3390, 3429, 3733, 3967, 4263, 4289], 'further': [2982, 3012, 3391, 3560, 3569, 3708, 4625, 4654], 'study': [2983], 'monoclonal': [2988, 3065, 3102, 4632], 'antibodies': [2989, 3129, 3152, 3496, 4026, 4067, 5206], 'JBP1.': [2991, 3107, 5238], 'Mice': [2992], 'immunized': [2994, 3401], 'fragment': [2999], '284–637),': [3004], 'hybridoma,': [3007], '6G8,': [3008, 3031, 3079, 4688], 'selected': [3010], 'analysis': [3013, 3322], 'characterize': [3030, 4616], 'radiolabeled': [3036, 3583, 3752], '(flag-JBP1)': [3039], 'fluid,': [3046], 'nonimmune': [3047, 3499], '(SP2/0),': [3050], 'NMS.': [3052], 'Immunoprecipitated': [3053], 'visualized': [3060, 3620, 3807], 'specifically': [3067, 3105, 4294, 5207, 5278], 'immunoprecipitated': [3068, 3153, 3492], '(Fig.1': [3070], 'A).': [3071, 3147, 3428, 3481], 'Western': [3072, 3425, 3458], 'blot': [3073], 'revealed': [3077, 3330, 5391], 'not': [3081, 3181, 3416, 3558, 3635, 3795, 3862, 4050, 4091, 4746, 5072, 5081], 'NMS,': [3082, 4051], 'about': [3087, 3163, 3255, 3282], '70': [3088], 'kilodaltons,': [3089, 3257], 'expected': [3091, 5517], 'size': [3092, 3729, 4767], '(Fig.': [3095, 3145, 3214, 3268, 3337, 3519, 4023, 4754], 'B).': [3097, 3216, 3248, 3521], 'Thus,': [3098, 5215], 'recognizes': [3106], 'identify': [3109], 'isolate': [3111], 'preparative': [3118], 'immunoprecipitations': [3119], '(6G8)': [3126, 3495, 4634], '(α-pICln).': [3130], 'extensive': [3132, 3503, 3611, 3798], 'washing,': [3133, 3612, 3799], 'immunoprecipitates': [3135, 3506], 'stained': [3141], 'Coomassie': [3143, 4704], 'Blue': [3144, 4705], 'Both': [3148], 'well': [3158, 5033, 5528, 5619], 'kilodaltons': [3165, 3284], 'band': [3169], 'excised': [3171], 'gel,': [3174], 'sequences,': [3178], 'did': [3180, 3634, 3704, 4090], 'match': [3182], 'any': [3183, 3849], 'nano-ES': [3189], 'MS/MS': [3190], 'AL533305)': [3224], 'downstream)': [3239], '(Fig.2': [3247], 'encodes': [3251], 'polypeptide': [3253], '36.7': [3256], 'migrated': [3259], 'above': [3260], '45-kilodalton': [3262, 3289], 'molecular': [3263, 3290], 'marker': [3265], 'see': [3272], 'below).': [3273], 'similar': [3276], 'pICln,': [3278, 3466, 3516, 3523, 3585, 4684, 4698, 4749], '26.2': [3283], 'migrates': [3286], 'near': [3287], 'marker.': [3292], 'discrepancy': [3294], 'due,': [3297], 'part,': [3301], 'fact': [3304], 'both': [3310], 'acidic': [3311], 'pI': [3315], '3.77': [3317], '4.84,': [3319], 'respectively.': [3320], 'Sequence': [3321, 3326], 'Analysis': [3327], 'server': [3328], '(bmerc-www.bu.edu/psa/)': [3329], 'six': [3334], 'repeats': [3336], 'B)': [3339], '(45Smith': [3340, 5311], 'T.F.': [3341, 5312, 5348, 5363, 5452], 'Gaitatzes': [3342, 5313], 'Saxena': [3344, 5315], 'Neer': [3346, 5317, 5349, 5453], 'E.J.': [3347, 5318, 5350, 5361, 5454], 'Trends': [3348, 5319], 'Biochem.': [3349, 5320], '24:': [3352, 5323], '181-185Abstract': [3353, 5324], '(1022)': [3361, 5332], '46Wall': [3364], 'M.A.': [3365, 5414], 'Coleman': [3366, 5415], 'Iniguez-Lluhi': [3370, 5419], 'J.A.': [3371, 5420], 'Posner': [3372, 5421], 'B.A.': [3373, 5422], 'Gilman': [3374, 5423], 'Sprang': [3376, 5425], '83:': [3380, 5429], '1047-1058Abstract': [3381, 5430], '(1018)': [3387, 5436], 'investigate': [3392], 'potential': [3396], 'component,': [3398], 'Using': [3406], 'sera': [3407], '(data': [3415, 3557, 3794, 3861, 5080], 'shown)': [3417, 3559], 'cell': [3422, 3439], 'blotting': [3426, 3459], '(Fig.3': [3427, 3480], 'confirm': [3430, 3709], 'sedimented': [3445, 3470], 'sucrose': [3448], 'gradient.': [3449], 'Fractions': [3450, 3482], 'collected': [3452], 'SDS-PAGE,': [3456], 'carried': [3461, 4469], 'out': [3462, 3916, 4265, 4470], 'detect': [3464, 3514], 'JBP1,': [3465, 3515, 3522, 3584, 4516, 4636, 4683, 4744, 5606], 'same': [3473], 'fractions': [3474], '(fractions': [3478], '12–15)': [3479], '12–15': [3483], 'containing': [3484], 'pooled': [3490], 'SP2/0': [3500], 'antibodies.': [3501, 4100], 'washing': [3504], 'immunoblotted': [3512], 'immunoprecipitate': [3531], 'fractions,': [3536], 'demonstrating': [3537], 'indeed': [3541], 'Transiently': [3548], 'associates': [3553], 'confirming': [3561], 'component.': [3567], 'studied': [3570], 'interactions': [3572, 3921, 3946], 'among': [3573], 'each': [3589, 3762, 5161], 'fused': [3594, 3771, 3784], '(GST-JBP1),': [3597], '(GST-pICln),': [3599], '(GST-MEP50)': [3602], 'or,': [3603, 3787], 'control,': [3606, 3790], 'alone.': [3609], 'fluorography': [3622, 3809], '(Fig.4).': [3623], 'Under': [3624], 'our': [3625, 5700], 'conditions,': [3627], 'homo-': [3636], 'hetero-oligomerize.': [3638], 'contrast': [3640], '47Rho': [3675], 'Choi': [3677, 4785], 'Seong': [3679, 4787], 'Y.R.': [3680, 4788], 'Cho': [3681, 4789], 'W.K.': [3682, 4790], 'Kim': [3683, 4791], 'S.H.': [3684, 4792], 'Im': [3685, 4793], '11393-11401Abstract': [3692, 4800], '(123)': [3700, 4808], 'homo-oligomerize.': [3705], 'These': [3706, 3931, 4101], 'abona': [3713], 'fide': [3714], 'suggest': [3720, 4104], 'oligomerization': [3722, 4782, 4812], 'contributes': [3725, 4763], 'test': [3734], 'whether': [3735, 3959, 4032], 'best': [3742, 4453], 'characterized': [3743, 4454], 'SmB,': [3753], 'SmD2,': [3755, 5067], 'SmD3,': [3756], 'SmE,': [3757], 'SmF,': [3758], 'SmG,': [3760], 'GST-MEP50,': [3765], '(GST': [3770, 3783], 'MEP50-(76–342),': [3778], 'MEP50-(1–75))': [3786], 'alone': [3793, 3856], 'shown).': [3796], '(Fig.5).': [3810], 'most': [3817], 'avidly': [3818, 4296], 'SmD2': [3822], 'detectable': [3826, 3846], 'SmD3': [3829, 4528, 5551], 'SmE.': [3831], 'significantly': [3837, 4052, 4092, 4764], 'less': [3838], 'There': [3843], 'no': [3845], 'under': [3857], 'conditions': [3860], 'Refs.': [3865], 'Scholar': [3885], 'very': [3911, 4742, 5305], 'unlikely,': [3912], 'cannot': [3914], 'rule': [3915], 'possibility': [3918, 5118, 5684], 'mediated': [3924, 3948], 'reticulocyte': [3929], 'lysate.': [3930], 'findings': [3932], 'indicate': [3933], 'domain.': [3953], 'next': [3955], 'wished': [3956, 4614], 'determine': [3958], 'end,': [3969, 4291], 'methylosomes': [3970], 'transiently': [3975], 'expressing': [3976], 'flag-JBP1': [3977], '6).': [4024], 'Anti-MEP50': [4025], 'verify': [4031], 'altered': [4034], 'NMS': [4041], 'negative': [4046], 'control.': [4047], 'Anti-MEP50,': [4048], 'reduced': [4053], 'toward': [4056, 5211], 'substrates.': [4060, 5214], 'removal': [4063], 'pre-binding': [4072, 4083], 'abolished': [4077], 'inhibitory': [4079, 4095], 'effect.': [4080], 'contrast,': [4082], 'reduce': [4093], 'effect': [4096], 'mediates': [4119], 'other': [4126, 5530], 'RNPs': [4127, 4279, 4308], '(10Fischer': [4128, 4969], '48Pellizzoni': [4189, 4329], '152:': [4203, 4343], '75-86Crossref': [4204, 4344], '(200)': [4207, 4347], '49Pellizzoni': [4210, 4350], 'Baccon': [4212, 4352], '11:': [4221, 4361], '1079-1088Abstract': [4222, 4362], '(170)': [4230, 4370], '50Jones': [4233, 4373], 'K.W.': [4234, 4374], 'Gorzynski': [4235, 4375], 'Hales': [4237, 4377], 'C.M.': [4238, 4378], 'Badbanchi': [4241, 4381], 'Terns': [4243, 4245, 4383, 4385], 'R.M.': [4244, 4384], 'M.P.': [4246, 4386, 5344, 5448], '38645-38651Abstract': [4252, 4392], '(137)': [4260, 4400], 'carry': [4264], 'functions,': [4267], 'needs': [4271], 'bring': [4273], 'together': [4274], 'facilitate': [4281, 4959], 'proper': [4283], 'individual': [4287], 'components.': [4288], 'key': [4304, 4600], 'depends': [4410], 'post-translational': [4413], 'its': [4423, 4817], 'cognate': [4424], 'For': [4451], 'macromolecular': [4474], 'methyltransferase,': [4515], 'converts': [4518], 'SmD1': [4526], 'sDMA,': [4530, 5549], 'thereby': [4531], 'targeting': [4532, 5523], 'them': [4533, 4832, 5234], 'Scholar,14Friesen': [4566], 'finding': [4597], 'suggested': [4598], 'process': [4607, 5177], 'assembly,': [4610], 'therefore': [4613, 4757], 'composition': [4618], 'detail.': [4626], 'using': [4628], 'co-immunoprecipitation': [4629], 'identified': [4639], 'additional': [4648, 5622], 'current': [4668], 'inventory': [4669], 'thus': [4676, 4720], 'indicates': [4677], 'composed': [4681, 4734], 'antibody,': [4691], 'co-immunoprecipitated': [4692], 'only': [4693, 4736], 'major': [4695], '(JBP1,': [4697], 'MEP50)': [4700], 'staining,': [4706], 'major,': [4714], 'stably': [4715], 'associated': [4716], 'identified.': [4722], 'It': [4723, 4948, 5239], 'interesting': [4725, 5062, 5173, 5683], 'note': [4727], 'although': [4729], 'apparently': [4733, 5402], 'nevertheless': [4741], 'large.': [4743], 'readily': [4750], 'oligomerizes': [4751], '4),': [4755], 'complex.': [4770, 5055, 5201], 'Indeed,': [4771, 5628], 'forms': [4773, 5307, 5397], 'intermolecular': [4774], 'disulfide': [4775], 'linkages,': [4776], 'ordered': [4779, 5147], 'regulated': [4781], '(47Rho': [4783], 'enzymatic': [4818], 'Oligomerization': [4820], 'allow': [4823], 'simultaneously': [4826], 'while': [4830, 5298], 'maintaining': [4831], 'spatial': [4836], 'arrangement': [4837, 4845], 'perhaps': [4839], 'contribute': [4842], 'complexes.': [4847], 'interact': [4854, 5510, 5603], 'reminiscent': [4860], '15Charroux': [4900], '16Charroux': [4923], 'possible': [4950, 5242], 'just': [4952], 'spatially': [5041], 'arrange': [5042], 'efficient': [5047], 'context,': [5058], 'particularly': [5061], 'interacts': [5065], 'substrate': [5074, 5165], 'methylation': [5076, 5150, 5236], 'Ref.': [5085], '51Brahms': [5086], 'Raymackers': [5088, 5554], 'Union': [5090, 5556], 'Keyser': [5093, 5559], 'Meheus': [5095, 5561], '17122-17129Abstract': [5104, 5570], '(251)': [5112, 5578], 'Scholar);': [5114], 'more': [5121], 'general': [5122], 'complete': [5149], 'many': [5153], 'need': [5156], 'larger': [5169], 'perspective,': [5170], 'require': [5183], 'activities': [5185], 'multiprotein': [5191], 'sequentially,': [5195], 'inhibit': [5208], 'modulate': [5219], 'positioning': [5233], 'enzyme': [5258], 'itself.': [5259], 'Whichever': [5260], 'case,': [5263], 'correct': [5284], 'modification.': [5286], 'repeat-containing': [5288], 'unique': [5291], 'functionally': [5296], 'having': [5299], 'motif,': [5303], '52Garcia-Higuera': [5335, 5439], 'Fenoglio': [5337, 5441], 'Y.': [5340, 5444], 'Lewis': [5341, 5445], 'Panchenko': [5343, 5447], 'Reiner': [5345, 5449], 'Biochemistry.': [5351, 5455], '35:': [5353, 5457], '13985-13994Crossref': [5354, 5458], '(164)': [5357, 5461], '53Neer': [5360], '84:': [5366], '175-178Abstract': [5367], '(186)': [5375], '(the': [5385], 'Gβ': [5386], 'subunit': [5387], 'heterotrimeric': [5389], 'G-proteins)': [5390], 'class': [5394], 'β-propeller': [5399], 'structure,': [5400], 'creates': [5403], 'stable': [5405], 'allowing': [5407], 'simultaneous': [5408], '(46Wall': [5413], '54Sondek': [5464], 'Bohm': [5466, 5487], 'Lambright': [5468], 'D.G.': [5469, 5484], 'Hamm': [5470, 5491], 'H.E.': [5471, 5492], 'Sigler': [5472, 5493], 'P.B.': [5473, 5494], '369-374Crossref': [5477], '(709)': [5480], '55Lambright': [5483], 'Sondek': [5485], 'Skiba': [5489], 'N.P.': [5490], '311-319Crossref': [5498], '(1055)': [5501], 'If': [5504], 'able': [5508], 'yet': [5531], 'unknown': [5532], 'symmetrical': [5538], 'dimethylation.': [5539], 'Only': [5540], 'so': [5545], 'far': [5546], '(51Brahms': [5552], 'myelin': [5582, 5633, 5677], 'basic': [5583, 5634, 5678], '(56Baldwin': [5585], 'Carnegie': [5587], 'P.R.': [5588], '1971;': [5590], '171:': [5591], '579-581Crossref': [5592], '(147)': [5595], 'identification': [5599], 'extend': [5610], 'range': [5612], 'sDMA-modified': [5623], 'if': [5625], 'such': [5626], 'exist.': [5627], '(34Branscombe': [5638], 'raising': [5681], 'play': [5688], 'biogenesis': [5693], 'myelin.': [5695], 'thank': [5697], 'members': [5698], 'laboratory,': [5701], 'especially': [5702], 'Drs.': [5703], 'Amelie': [5704], 'Gubitz': [5705], 'Livio': [5707], 'Pellizzoni,': [5708], 'helpful': [5710], 'discussion': [5711], 'comments': [5713], 'manuscript.': [5716]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2119931165', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 22}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 13}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2025-01-10T04:49:48.481526', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
