Publication Information

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'https://openalex.org/W97523097'], 'related_works': ['https://openalex.org/W4248586904', 'https://openalex.org/W2401632846', 'https://openalex.org/W2366072566', 'https://openalex.org/W2318883589', 'https://openalex.org/W2135561672', 'https://openalex.org/W2099143291', 'https://openalex.org/W2032842127', 'https://openalex.org/W2019867611', 'https://openalex.org/W1831189467', 'https://openalex.org/W1601657500'], 'abstract_inverted_index': {'Growth': [0, 189, 441, 1916], 'hormone': [1, 190, 379, 381, 442, 2608], '(GH)': [2, 191], 'regulates': [3, 192, 1431], 'transcription': [4, 193, 388, 499, 518, 629, 647, 651, 853, 901, 925, 1008, 1178, 1295, 1313, 1935], 'factors': [5, 194, 648, 902, 3822], 'associated': [6, 195, 3947], 'with': [7, 41, 137, 196, 230, 326, 1796, 1830, 2084, 2087, 2212, 2443, 2475, 2607, 2660, 2761, 2770, 2824, 2879, 2890, 2996, 3210, 3220, 3256, 3290, 3305, 3376, 3482, 3546, 3725, 3739, 3948, 4002, 4073, 4097, 4133, 4220, 4235, 4251, 4290, 4405, 4432, 4453], 'c-fos,': [8, 96, 197, 285], 'including': [9, 198, 3070], 'C/EBPβ.': [10, 81, 166, 199, 270, 355, 3288, 3480, 4291], 'Two': [11, 200], 'forms': [12, 201, 978], 'of': [13, 31, 62, 70, 80, 86, 92, 100, 117, 141, 165, 170, 183, 202, 220, 251, 259, 269, 275, 281, 289, 306, 330, 354, 359, 372, 387, 446, 494, 497, 549, 560, 563, 576, 623, 628, 636, 641, 652, 854, 900, 921, 979, 993, 1030, 1061, 1160, 1226, 1238, 1281, 1290, 1294, 1419, 1434, 1443, 1462, 1465, 1490, 1495, 1508, 1542, 1598, 1758, 1785, 1824, 1861, 1864, 1881, 1908, 1926, 1933, 1940, 1960, 1975, 2004, 2019, 2107, 2134, 2279, 2285, 2288, 2331, 2349, 2364, 2372, 2407, 2414, 2450, 2458, 2485, 2512, 2528, 2579, 2598, 2734, 2829, 2837, 2909, 2917, 2930, 2994, 3015, 3174, 3181, 3189, 3197, 3202, 3207, 3229, 3247, 3287, 3309, 3351, 3361, 3364, 3369, 3424, 3448, 3456, 3470, 3475, 3479, 3486, 3509, 3511, 3520, 3539, 3555, 3565, 3572, 3633, 3638, 3652, 3665, 3682, 3717, 3728, 3743, 3768, 3795, 3811, 3814, 3906, 3941, 3950, 3954, 3974, 3999, 4009, 4020, 4035, 4042, 4050, 4076, 4085, 4105, 4114, 4139, 4157, 4168, 4177, 4182, 4227, 4240, 4275, 4298, 4310, 4327, 4330, 4360, 4382], 'C/EBPβ,': [14, 203, 890, 930, 980, 3016], 'liver-activating': [15, 204, 391, 984], 'protein': [16, 21, 205, 210, 392, 395, 410, 435, 999], '(LAP)': [17, 206], 'and': [18, 33, 49, 64, 89, 111, 127, 160, 177, 207, 222, 238, 253, 278, 300, 316, 349, 366, 385, 452, 514, 618, 638, 893, 927, 976, 1006, 1105, 1162, 1181, 1223, 1228, 1436, 1438, 1445, 1480, 1502, 1526, 1556, 1617, 1640, 1649, 1661, 1686, 1698, 1706, 1728, 1737, 1751, 1778, 1805, 1852, 1893, 1978, 2010, 2030, 2069, 2072, 2102, 2130, 2136, 2215, 2255, 2310, 2339, 2376, 2420, 2480, 2503, 2571, 2601, 2668, 2810, 2883, 2963, 3012, 3061, 3064, 3183, 3204, 3241, 3311, 3344, 3359, 3497, 3528, 3557, 3696, 3809, 3826, 4024, 4121, 4155, 4184, 4186, 4190, 4211, 4218, 4257, 4314, 4323, 4349, 4366, 4391], 'liver': [19, 208, 393, 997], 'inhibitory': [20, 209, 394, 928, 998], '(LIP),': [22, 211, 1000], 'are': [23, 39, 212, 228, 643, 987, 2198, 2403, 3544, 4205, 4325], 'dephosphorylated': [24, 213, 3477], 'in': [25, 120, 185, 214, 309, 374, 490, 654, 851, 967, 1063, 1098, 1230, 1233, 1244, 1459, 1512, 1742, 1755, 1769, 1782, 1816, 2104, 2217, 2274, 2281, 2361, 2422, 2482, 2525, 2590, 2783, 2832, 2904, 2934, 2951, 2986, 2990, 3066, 3283, 3334, 3336, 3366, 3430, 3453, 3495, 3515, 3746, 3765, 3780, 3803, 3828, 3971, 4005, 4047, 4092, 4222, 4237, 4272, 4305, 4320, 4351, 4411, 4449], 'GH-treated': [26, 215, 3496], '3T3-F442A': [27, 121, 216, 310, 1231, 1516, 1735, 2077, 2208, 2416, 2594, 3071, 3735, 3804, 4000, 4095, 4216], 'fibroblasts.': [28, 217], 'GH-induced': [29, 218, 1488, 3367, 4137], 'dephosphorylation': [30, 61, 79, 99, 113, 164, 219, 250, 268, 288, 302, 353, 1225, 1433, 1442, 1464, 1489, 3014, 3180, 3201, 3228, 3249, 3286, 3308, 3368, 3485, 3554, 4181], 'LAP': [32, 63, 87, 119, 126, 129, 138, 171, 221, 252, 276, 308, 315, 318, 327, 360, 1227, 1437, 1444, 1496, 1843, 2720, 2735, 3182, 3203, 3242, 3312, 3343, 3487, 4183, 4189, 4202, 4210, 4256, 4322, 4344, 4369, 4385, 4422], 'LIP': [34, 93, 223, 282, 1025, 1062, 1229, 1435, 1446, 1845, 2722, 3230, 3310, 3345, 3428, 3449, 3494, 4191, 4204, 4212, 4258, 4324, 4346, 4371, 4388, 4424], 'is': [35, 224, 965, 1276, 3056, 3320, 3353, 3568, 3762, 3818, 3899, 3903, 4395], 'reduced': [36, 145, 225, 334, 4135], 'when': [37, 226, 3252, 3901, 4267], 'cells': [38, 124, 227, 313, 968, 1534, 1590, 1739, 1766, 1812, 1827, 2078, 2209, 2417, 2595, 2739, 2927, 3209, 3253, 3432, 3736, 4001, 4096, 4217, 4342, 4420], 'preincubated': [40, 229], 'phosphatidylinositol': [42, 231, 401], '3′-kinase': [43, 232], '(PI3K)': [44, 233], 'inhibitors.': [45, 234], 'GH': [46, 158, 235, 347, 501, 511, 580, 624, 657, 1156, 1219, 1430, 1478, 1602, 1833, 3008, 3055, 3198, 3221, 3263, 3301, 3339, 3521, 3547, 3634, 3658, 3685, 3749, 3766, 3783, 3806, 3944, 4003, 4078, 4115, 4152, 4171, 4178], 'activates': [47, 236], 'Akt': [48, 237, 1976, 1984, 2071, 2192, 3567, 3639, 3653, 3667, 3683, 3718, 3729, 3745, 3778, 3812, 3827, 3907, 3942], 'inhibits': [50, 239, 1007, 1026], 'glycogen': [51, 240, 419], 'synthase': [52, 241, 420], 'kinase-3': [53, 242, 421], '(GSK-3).': [54, 243], 'Lithium,': [55, 244, 3770], 'a': [56, 245, 444, 570, 905, 913, 1002, 1221, 1473, 1949, 2012, 2282, 2370, 2893, 2896, 3010, 3279, 3324, 3378, 3549, 3569, 3650, 3771, 3963, 3967, 4006, 4162, 4193], 'GSK-3': [57, 74, 144, 246, 263, 333, 1663, 1677, 2020, 2073, 2218, 2270, 2399, 2486, 2500, 2899, 3365, 3379, 3471, 3560, 3772, 3792, 3816, 3898, 3955, 3968, 4010, 4021, 4025, 4140, 4158, 4169, 4206, 4236, 4276, 4311], 'inhibitor,': [58, 247, 3260, 3773], 'increases': [59, 84, 168, 248, 273, 357, 1157, 1493, 4335], 'GH-dependent': [60, 249, 3441], 'LIP.': [65, 254, 3205], 'Both': [66, 108, 255, 297], 'arein': [67, 256], 'vitro': [68, 257, 4321], 'substrates': [69, 258, 1665, 4326], 'GSK-3,': [71, 128, 260, 317, 3362, 4077, 4087, 4198], 'suggesting': [72, 97, 132, 261, 286, 321, 3467, 3757], 'that': [73, 98, 133, 153, 262, 287, 322, 342, 1059, 1279, 1487, 1971, 2683, 3316, 3468, 3526, 3559, 3647, 3758, 3823, 3939, 4100, 4151, 4201, 4283, 4319], 'inactivation': [75, 264, 3360, 4049, 4075], 'contributes': [76, 265], 'to': [77, 95, 105, 173, 180, 266, 284, 294, 362, 369, 649, 656, 849, 896, 912, 1093, 1164, 1172, 1176, 1235, 1240, 1310, 1424, 1439, 1450, 1452, 1498, 1514, 1701, 1810, 1952, 2000, 2011, 2015, 2584, 2587, 2848, 2943, 2979, 3003, 3058, 3199, 3218, 3262, 3300, 3322, 3327, 3330, 3338, 3355, 3357, 3443, 3489, 3552, 3635, 3661, 3689, 3748, 3776, 3782, 3961, 4028, 4081, 4174, 4179], 'GH-promoted': [78, 267, 3227, 3248, 3285, 3307], 'Alkaline': [82, 271], 'phosphatase': [83, 272, 413, 1651, 4434], 'binding': [85, 91, 116, 130, 169, 274, 280, 305, 319, 358, 916, 1159, 1237, 1305, 1494, 2676], 'homodimers': [88, 94, 277, 283, 4386, 4389], 'decreases': [90, 279], 'C/EBPβ': [101, 184, 290, 373, 1091, 1239, 1466, 1491, 1511, 1961, 2033, 2440, 2451, 2589, 3370, 3556, 4364], 'modifies': [102, 291], 'their': [103, 292, 1303, 1308, 1448], 'ability': [104, 293, 1449, 3196, 3632, 3960, 4176], 'bind': [106, 295, 1451], 'DNA.': [107, 296, 1453], 'alkaline': [109, 298, 412, 1650, 2830, 4433], 'phosphatase-': [110, 299], 'GH-mediated': [112, 301, 3726, 4018, 4074], 'comparably': [114, 303], 'increase': [115, 304, 3491, 3662, 4082, 4108], 'endogenous': [118, 307, 4414], 'cells.': [122, 311, 3499], 'In': [123, 312, 1086, 2816, 3500], 'overexpressing': [125, 314, 4343, 4421], 'decreases,': [131, 320], 'GSK-3-mediated': [134, 323], 'phosphorylation': [135, 324, 627, 635, 640, 1292, 2572, 3335, 3358, 3510, 3637, 3779, 3808, 4034, 4138, 4154], 'interferes': [136, 325], 'binding.': [139, 328, 4337], 'Expression': [140, 329], 'constitutively': [142, 331, 2897], 'active': [143, 332, 2898], 'GH-stimulated': [146, 186, 335, 375, 633, 3715], 'c-fos': [147, 175, 187, 336, 364, 376, 566, 653, 855, 1166, 1184, 1500, 1509, 1929, 2665], 'promoter': [148, 176, 337, 365, 1501, 1850, 1930], 'activity.': [149, 338, 2981], 'These': [150, 339, 1454, 3542, 4148, 4316], 'studies': [151, 340, 1455, 1485], 'indicate': [152, 341, 3801, 4150, 4318], 'PI3K/Akt/GSK-3': [154, 343, 1457], 'mediates': [155, 344, 3178], 'signaling': [156, 345, 507, 1426, 1458, 1474, 3176], 'between': [157, 346, 509, 1101, 1476], 'receptor': [159, 348, 382, 512, 1479], 'the': [161, 174, 181, 350, 363, 370, 495, 510, 561, 564, 626, 897, 924, 931, 1027, 1087, 1099, 1158, 1165, 1177, 1183, 1241, 1291, 1420, 1432, 1460, 1463, 1477, 1481, 1499, 1539, 1543, 1662, 1702, 1817, 1848, 1927, 1934, 1941, 1957, 1983, 2188, 2275, 2324, 2329, 2350, 2388, 2398, 2447, 2517, 2523, 2526, 2580, 2591, 2604, 2674, 2679, 2819, 2833, 2884, 2905, 3187, 3195, 3208, 3211, 3226, 3284, 3291, 3306, 3317, 3422, 3425, 3440, 3444, 3454, 3473, 3476, 3490, 3507, 3516, 3533, 3537, 3663, 3714, 3741, 3759, 3972, 4036, 4051, 4083, 4136, 4175, 4199, 4223, 4238, 4252, 4268, 4273, 4306, 4352, 4454], 'nucleus,': [162, 351], 'promoting': [163, 352], 'Dephosphorylation': [167, 356], 'complexes': [172, 361, 1497, 4367, 4383], 'may': [178, 367, 1503, 3561], 'contribute': [179, 368, 4173], 'participation': [182, 371], 'expression.': [188, 377, 492], 'growth': [378, 380, 431, 3821], 'signal': [383], 'transducers': [384], 'activators': [386], 'CCAAT/enhancer-binding': [389], 'proteins': [390, 985, 2532, 2785, 4246, 4301], 'base': [396], 'pair(s)': [397], 'serum': [398, 407, 438, 1185, 1616, 1620, 1754, 1777, 2599, 2931, 4294], 'response': [399, 439, 655, 1186, 1513, 3329, 3337, 3747, 3781], 'element': [400, 1187], '3-kinase': [402], 'Chinese': [403, 1531], 'hamster': [404, 1532], 'ovary': [405, 1533], 'bovine': [406], 'albumin': [408, 1627], 'mitogen-activate': [409], 'kinase': [411, 416, 418, 4052, 4285], 'extracellular': [414], 'signal-regulated': [415], 'MAPK/ERK': [417], 'cytomegalovirus': [422], 'Rous': [423], 'sarcoma': [424], 'virus': [425], 'polyacrylamide': [426], 'gel': [427], 'electrophoresis': [428], 'wild-type': [429, 2664], 'platelet-derived': [430], 'factor': [432], 'cAMP-response': [433], 'element-binding': [434], 'activator': [436], 'protein-1': [437], 'factor.': [440], '(GH)1exhibits': [443], 'variety': [445], 'effects': [447, 622], 'on': [448, 625, 2007, 2079, 2200, 2343, 3023, 3194, 3655, 3732, 4039, 4044], 'somatic': [449], 'growth,': [450], 'differentiation,': [451], 'metabolism': [453], '(1Froesch': [454], 'E.R.': [455, 3092], 'Schmid': [456], 'C.': [457, 520, 545, 584, 687, 695, 748, 781, 802, 824, 1382, 1384, 2160, 2168, 3100, 3127, 3157], 'Schwander': [458], 'J.': [459, 461, 522, 543, 592, 608, 659, 669, 670, 689, 697, 698, 723, 754, 779, 800, 822, 825, 857, 869, 870, 936, 948, 949, 1077, 1190, 1202, 1203, 1246, 1258, 1259, 1362, 1369, 1889, 2040, 2052, 2053, 2162, 2170, 2171, 2542, 2554, 2555, 2622, 2634, 2635, 2688, 2700, 2701, 3026, 3038, 3039, 3114, 3136, 3158, 3622, 3842, 3873, 3889, 3918, 3982], 'Zapf': [460], 'Annu.': [462, 477, 525], 'Rev.': [463, 478, 526], 'Physiol.': [464, 479, 527], '1985;': [465, 480], '47:': [466, 481], '443-464Crossref': [467], 'PubMed': [468, 483, 531, 596, 613, 681, 709, 734, 760, 786, 808, 836, 881, 960, 1020, 1049, 1081, 1119, 1137, 1151, 1214, 1270, 1325, 1340, 1354, 1378, 1399, 1412, 1581, 2064, 2182, 2566, 2646, 2712, 2756, 2874, 3050, 3084, 3105, 3123, 3145, 3167, 3395, 3416, 3597, 3610, 3626, 3853, 3877, 3893, 3929, 3993, 4067], 'Google': [469, 484, 534, 599, 616, 684, 712, 737, 763, 789, 811, 839, 884, 963, 1023, 1052, 1084, 1122, 1140, 1154, 1217, 1273, 1328, 1343, 1357, 1379, 1402, 1415, 1584, 1921, 2067, 2185, 2569, 2649, 2715, 2759, 2877, 3053, 3087, 3108, 3124, 3146, 3168, 3398, 3417, 3600, 3613, 3629, 3856, 3880, 3896, 3932, 3996, 4070], 'Scholar,': [470, 535, 600, 685, 713, 738, 764, 790, 812, 1123, 1141, 1329, 1344, 1358, 1380, 1403, 3088, 3109, 3125, 3147, 3399, 3601, 3614, 3857, 3881], '2Isaksson': [471], 'O.G.': [472], 'Eden': [473], 'S.': [474, 729, 742, 3390], 'Jansson': [475], 'J.O.': [476], '483-499Crossref': [482], 'Scholar),': [485, 617, 2570, 3418], 'which': [486, 887, 1169, 1297, 1429, 3419], 'often': [487], 'involve': [488], 'changes': [489, 2363, 3333], 'gene': [491, 498, 577, 1283, 1312, 2681], 'Analysis': [493, 2993], 'regulation': [496, 575, 1289, 1461], 'by': [500, 579, 904, 1428, 1467, 1510, 1520, 1549, 1593, 1605, 1847, 1876, 1887, 1903, 2145, 2328, 2381, 2521, 2535, 2575, 2719, 2725, 2730, 2860, 2932, 3019, 3642, 3684, 3820, 3943, 3958, 4090, 4161, 4170, 4374], 'has': [502, 567, 619, 1055], 'provided': [503, 1519, 1548, 1592, 1604, 1875, 1886, 1902], 'additional': [504], 'insight': [505], 'into': [506, 2387], 'mechanisms': [508], '(GHR)': [513], 'nuclear': [515, 2784], 'events': [516, 1427], 'regulating': [517], '(3Carter-Su': [519], 'Schwartz': [521, 542, 607, 668, 696, 722, 778, 799, 821, 868, 947, 1201, 1257, 2051, 2169, 2553, 2633, 2699, 3037], 'Smit': [523], 'L.S.': [524, 537, 541, 766, 792], '1996;': [528, 757, 805, 3392, 3408, 3874], '58:': [529], '187-207Crossref': [530], 'Scopus': [532, 597, 614, 682, 710, 735, 761, 787, 809, 837, 882, 961, 1021, 1050, 1082, 1120, 1138, 1152, 1215, 1271, 1326, 1341, 1355, 1400, 1413, 1582, 2065, 2183, 2567, 2647, 2713, 2757, 2875, 3051, 3085, 3106, 3396, 3598, 3611, 3627, 3854, 3878, 3894, 3930, 3994, 4068], '(275)': [533], '4Smit': [536], 'Meyer': [538, 662, 793, 815], 'D.J.': [539, 663, 715, 794, 816, 3839, 3915], 'Argetsinger': [540], 'Carter-Su': [544, 694, 780, 801, 823, 2167, 3099, 3156], 'Kostyo': [546], 'J.L.': [547], 'Handbook': [548], 'Physiology.': [550], '5.': [551], 'Oxford': [552], 'University': [553], 'Press,': [554], 'New': [555, 1681, 1991], 'York1999:': [556], '445-480Google': [557], 'Scholar).': [558, 840, 885, 1024, 1053, 1085, 1155, 1218, 1274, 1416, 1585, 2650, 2716, 3054, 3169, 3630, 3897, 3933, 3997, 4071], 'Regulation': [559], 'expression': [562, 578, 1284], 'proto-oncogene': [565], 'served': [568], 'as': [569, 969, 983, 996, 1472, 1839, 2036, 2074, 2156, 2405, 2538, 2611, 2618, 2945, 3006, 3017, 3789, 4088, 4379], 'useful': [571], 'model': [572], 'for': [573, 645, 2032, 2070, 2267, 2318, 2369, 2462, 2603, 2654, 2841, 2939, 3281, 3342, 3493, 4197, 4255, 4363, 4458], 'studying': [574], '(5Doglio': [581], 'A.': [582, 730, 740, 770, 1570, 1670, 3129, 3391, 3583, 3835, 3911], 'Dani': [583], 'Fredrikson': [585], 'G.': [586, 590, 602, 604, 798, 859, 938, 1192, 1248, 1550, 1566, 1568, 2042, 2544, 2624, 2690, 3028, 3135], 'Grimaldi': [587], 'P.': [588, 1010, 1039, 1388, 1888, 3887, 4058], 'Ailhaud': [589], 'EMBO': [591, 1076, 3621], '1987;': [593, 2753, 2871], '6:': [594, 1919, 3409], '4011-4016Crossref': [595], '(92)': [598], '6Gurland': [601], 'Ashcom': [603], 'Cochran': [605, 720], 'B.H.': [606, 721], 'Endocrinology.': [609, 782, 3101], '1990;': [610], '127:': [611], '3187-3195Crossref': [612], '(108)': [615, 1083], 'demonstrated': [620, 1058], 'diverse': [621], 'factors.': [630], 'For': [631, 2732], 'example,': [632], 'tyrosine': [634], 'STATs': [637], 'serine': [639], 'Elk-1': [642], 'required': [644], 'these': [646, 1484, 3175, 3276, 3347, 3540, 3799], 'activate': [650, 1311, 3059, 3824], '(7Liao': [658], 'Hodge': [660, 862, 941, 1195, 1251, 2045, 2547, 2627, 2693, 3031], 'C.L.': [661, 863, 942, 1196, 1252, 2046, 2548, 2628, 2694, 3032], 'Ho': [664], 'P.S.': [665, 3382], 'Rosenspire': [666], 'K.C.': [667], 'Biol.': [671, 699, 826, 871, 950, 1204, 1260, 1370, 1576, 2054, 2172, 2556, 2636, 2702, 2752, 2870, 3040, 3115, 3137, 3159, 3407, 3843, 3919, 3983], 'Chem.': [672, 700, 827, 872, 951, 1205, 1261, 1371, 2055, 2173, 2557, 2637, 2703, 3041, 3116, 3138, 3160, 3844, 3920, 3984], '1997;': [673, 783, 3102], '272:': [674], '25951-25958Abstract': [675], 'Full': [676, 678, 704, 706, 831, 833, 876, 878, 955, 957, 1017, 1046, 1209, 1211, 1265, 1267, 1322, 1375, 2059, 2061, 2177, 2179, 2561, 2563, 2641, 2643, 2707, 2709, 3045, 3047, 3120, 3142, 3164, 3411, 3413, 3594, 3848, 3850, 3924, 3926, 3988, 3990], 'Text': [677, 679, 705, 707, 832, 834, 877, 879, 956, 958, 1018, 1047, 1210, 1212, 1266, 1268, 1323, 1376, 2060, 2062, 2178, 2180, 2562, 2564, 2642, 2644, 2708, 2710, 3046, 3048, 3121, 3143, 3165, 3412, 3414, 3595, 3849, 3851, 3925, 3927, 3989, 3991], 'PDF': [680, 708, 835, 880, 959, 1019, 1048, 1213, 1269, 1324, 1377, 2063, 2181, 2565, 2645, 2711, 3049, 3122, 3144, 3166, 3415, 3596, 3852, 3928, 3992], '(63)': [683], '8Hodge': [686], 'Liao': [688, 2161], 'Stofega': [690, 2163], 'M.': [691, 746, 1071, 1075, 1129, 1317, 1331, 1392, 1394, 1528, 1595, 1878, 2164, 3074, 4060], 'Guan': [692, 2165, 3097], 'K.': [693, 2166, 3581], '1998;': [701, 1409, 2174, 3985], '273:': [702, 2175, 3986], '31327-31336Abstract': [703, 2176], '(229)': [711, 2184], '9Meyer': [714], 'Stephenson': [716], 'E.W.': [717], 'Johnson': [718], 'L.': [719, 865, 944, 1198, 1254, 1865, 2048, 2550, 2630, 2696, 3034, 3151, 3403], 'Proc.': [724, 1573, 3385], 'Natl.': [725, 3386], 'Acad.': [726, 3387], 'Sci.': [727, 3388], 'U.': [728, 1012, 1041, 1858, 3389], '1993;': [731, 1396], '90:': [732], '6721-6725Crossref': [733], '(72)': [736], '10Sotiropoulos': [739], 'Moutoussamy': [741], 'Renaudie': [743], 'F.': [744, 750], 'Clauss': [745], 'Kayser': [747], 'Gouilleux': [749], 'Kelly': [751], 'P.A.': [752], 'Finidori': [753], 'Mol.': [755, 803, 2750, 2868], 'Endocrinol.': [756, 804], '10:': [758, 806], '998-1009Crossref': [759], '(125)': [762], '11Smit': [765], 'VanderKuur': [767], 'J.A.': [768, 3090], 'Stimage': [769], 'Han': [771], 'Y.': [772, 3883], 'Luo': [773], 'G.,': [774], 'Yu-': [775], 'Lee': [776], 'L.-y.': [777], '138:': [784, 3103], '3426-3434Crossref': [785], '(64)': [788], '12Smit': [791], 'Billestrup': [795, 1558], 'N.': [796, 1557, 1564], 'Norstedt': [797, 1551, 1567, 3134], '519-533Crossref': [807], '(181)': [810], '13Campbell': [813], 'G.S.': [814, 3149], 'Raz': [817], 'R.': [818, 1346], 'Levy': [819], 'D.E.': [820], '1995;': [828, 1134, 1918, 3591, 3607, 3623, 3845, 3921, 4064], '270:': [829, 3846, 3922], '3974-3979Abstract': [830], '(169)': [838], 'The': [841, 918, 974, 990, 1417, 1657, 1713, 1869, 1899, 2195, 2531, 2974, 3631, 3680, 3702, 3708, 3952, 4017, 4107, 4399, 4407, 4441], 'CCAAT/Enhancer-Binding': [842], 'Proteins': [843], '(C/EBPs)': [844], 'have': [845], 'recently': [846], 'been': [847, 1057], 'shown': [848, 4396], 'participate': [850], 'GH-regulated': [852, 933, 3179], '(14Liao': [856, 935, 1189, 2039, 2541, 2621, 2687, 3025], 'Piwien-Pilipuk': [858, 937, 1191, 1247, 2041, 2543, 2623, 2689, 3027], 'Ross': [860, 939, 1193, 1249, 2043, 2545, 2625, 2691, 3029], 'S.E.': [861, 940, 1194, 1250, 2044, 2546, 2626, 2692, 3030], 'Sealy': [864, 943, 1197, 1253, 1866, 2047, 2549, 2629, 2695, 3033], 'MacDougald': [866, 945, 1199, 1255, 2049, 2551, 2631, 2697, 3035], 'O.A.': [867, 946, 1200, 1256, 2050, 2552, 2632, 2698, 3036], '1999;': [873, 952, 1148, 1206, 1262, 2056, 2558, 2638, 2704, 3042], '274:': [874, 953, 1207, 1263, 2057, 2559, 2639, 2705, 3043], '31597-31604Abstract': [875, 954, 1208, 1264, 2058, 2560, 2640, 2706, 3044], '(38)': [883, 962, 1216, 1272, 2066, 2568, 2648, 2714, 3052], 'C/EBPs,': [886], 'include': [888], 'C/EBPα,': [889], 'C/EBPδ,': [891], 'C/EBPε,': [892], 'C/EBPζ/CHOP,': [894], 'belong': [895], 'bZIP': [898], 'family': [899], 'characterized': [903], 'C-terminal': [906, 2448], 'dimerization': [907], 'domain': [908, 1005, 1545, 2449], '(leucine': [909], 'zipper)': [910], 'adjacent': [911], 'basic': [914], 'DNA': [915, 1304, 2911, 4336], 'domain.': [917], 'N-terminal': [919, 1540], 'region': [920], 'C/EBPs': [922], 'contains': [923, 1923], 'activation': [926, 1507, 3350, 3716, 3727, 3767, 3810, 3940], 'domains.': [929], 'prominent': [932, 4244], 'form': [934, 992, 3447, 3478], 'Scholar)': [964, 1922, 2068, 2186, 2760, 2878], 'present': [966, 1421], 'three': [970, 2362, 2473], 'alternate': [971], 'translation': [972], 'products.': [973], '32-': [975], '35-kDa': [977], 'also': [981, 1056, 3774], 'known': [982, 995, 3057, 3354], '(LAP),': [986], 'potent': [988], 'transactivators.': [989], '20-kDa': [991], 'C/ΕBPβ,': [994], 'possesses': [1001], 'truncated': [1003], 'transactivation': [1004], '(15Descombes': [1009, 1038], 'Schibler': [1011, 1040, 1859], 'Cell.': [1013, 1042, 1318, 2751, 2869, 3590], '1991;': [1014, 1043, 1116, 1351], '67:': [1015, 1044], '569-579Abstract': [1016, 1045], '(857)': [1022, 1051], 'transactivating': [1028], 'potential': [1029], 'LAP,': [1031, 4331], 'even': [1032], 'at': [1033, 1762, 1789, 1834, 1956, 2263, 2321, 2465, 2514, 2657, 2813, 2844], 'relatively': [1034], 'low': [1035], 'molar': [1036], 'ratios': [1037], 'It': [1054, 1275], 'overexpression': [1060], 'hepatocytes': [1064], 'overcomes': [1065], 'LAP-mediated': [1066], 'cell': [1067, 1102, 2139, 2780, 3068, 3830], 'cycle': [1068, 1103], 'arrest': [1069], '(16Buck': [1070], 'Turler': [1072], 'H.': [1073, 1522, 2749, 2867, 3076], 'Chojkier': [1074, 1393], '1994;': [1078, 1578, 3081, 3890], '13:': [1079, 1149], '851-860Crossref': [1080], 'adipocyte': [1088], 'differentiation': [1089, 1107], 'program,': [1090], 'appears': [1092], 'play': [1094], 'an': [1095, 1756, 1783, 1997, 2444, 2455, 2971, 3020, 3645, 4098], 'important': [1096], 'role': [1097, 3280], 'transition': [1100], 'progression': [1104], 'terminal': [1106], '(17Cao': [1108], 'Z.': [1109, 1127, 1333], 'Umek': [1110], 'R.M.': [1111], 'McKnight': [1112, 1130, 1363], 'S.L.': [1113, 1131, 1364], 'Genes': [1114, 1132, 1146, 1349], 'Dev.': [1115, 1133, 1147, 1350], '5:': [1117, 1352], '1538-1552Crossref': [1118], '(1338)': [1121], '18Yeh': [1124], 'W.C.': [1125], 'Cao': [1126, 1332], 'Classon': [1128], '9:': [1135], '168-181Crossref': [1136], '(807)': [1139], '19Tang': [1142], 'Q.-Q.': [1143], 'Lane': [1144], 'M.D.': [1145], '2231-2241Crossref': [1150], '(306)': [1153, 1342], 'C/ΕBPβ': [1161], 'C/EBPδ': [1163], 'C/EBP': [1167, 1242, 2666, 2675], 'site,': [1168, 1180], 'lies': [1170, 3793], '−295': [1171], '−303': [1173], 'bp': [1174, 1925], 'relative': [1175], 'start': [1179, 1936], 'overlaps': [1182], '(SRE)': [1188], 'promotes': [1220, 3807], 'rapid': [1222, 3011], 'transient': [1224, 3013], 'cells,': [1232, 3805], 'addition': [1234, 2330], 'increasing': [1236], 'site': [1243, 1937, 2667, 2677], 'c-fos(14Liao': [1245], 'well': [1277], 'established': [1278], 'modulation': [1280], 'target': [1282], 'can': [1285, 1298], 'be': [1286, 3323, 3562, 3937, 3946], 'achieved': [1287], 'through': [1288], 'state': [1293], 'factors,': [1296], 'positively': [1299], 'or': [1300, 1831, 1844, 2151, 2193, 2305, 2609, 2673, 2736, 2766, 2771, 2825, 2835, 2850, 2891, 2907, 2914, 2965, 2988, 3191, 3513, 3518, 4041, 4225, 4308, 4345, 4356, 4423, 4431, 4448], 'negatively': [1301], 'alter': [1302, 3777], 'affinity': [1306], 'and/or': [1307, 2721, 4203, 4370], 'capacity': [1309], '(20Hunter': [1314], 'T.': [1315, 1390, 3153], 'Karin': [1316, 1391], '1992;': [1319, 1337, 1372, 3117, 3139, 3161], '70:': [1320], '375-387Abstract': [1321], '(1118)': [1327], '21Wegner': [1330], 'Rosenfeld': [1334], 'M.G.': [1335], 'Science.': [1336], '256:': [1338], '370-373Crossref': [1339], '22Metz': [1345], 'Ziff': [1347], 'E.': [1348], '1754-1766Crossref': [1353], '(301)': [1356], '23Mahoney': [1359], 'C.W.': [1360], 'Shuman': [1361], 'Chen': [1365], 'H.C.': [1366], 'Huang': [1367], 'K.P.': [1368], '267:': [1373, 3118, 3140, 3162], '19396-19403Abstract': [1374], '24Trautwein': [1381], 'Caelles': [1383], 'van': [1385], 'der': [1386], 'Geer': [1387], 'Hunter': [1389], 'Nature.': [1395, 3606, 4063], '364:': [1397], '544-547Crossref': [1398], '(293)': [1401], '25Bullock': [1404], 'B.P.': [1405], 'Habener': [1406], 'J.F.': [1407], 'Biochemistry.': [1408], '37:': [1410], '3795-3809Crossref': [1411], '(135)': [1414], 'focus': [1418], 'study': [1422], 'was': [1423, 1603, 1633, 1652, 1678, 1717, 1724, 1874, 1885, 1895, 2272, 2353, 2379, 2392, 2441, 2519, 2573, 2582, 2968, 2984, 3001, 3250, 3371, 3450, 3640, 3659, 3750, 3956, 4022, 4079, 4109, 4208, 4270, 4295], 'identify': [1425, 2588], 'determine': [1440], 'whether': [1441, 3172], 'modulates': [1447], 'implicate': [1456], 'GH,': [1468], 'thereby': [1469, 1504], 'identifying': [1470], 'PI3K': [1471, 3060, 3190, 3212, 3259, 3282, 3352, 3550, 3573, 3709, 3825], 'intermediate': [1475], 'nucleus.': [1482], 'Furthermore,': [1483], 'demonstrate': [1486], 'dramatically': [1492], 'modulate': [1505, 3553], 'transcriptional': [1506], 'GH.': [1515, 3331], 'fibroblasts': [1517, 3072], 'were': [1518, 1547, 1591, 1610, 1621, 1643, 1666, 1692, 1708, 1732, 1740, 1767, 1794, 1813, 1828, 1854, 1962, 1988, 2022, 2034, 2082, 2143, 2154, 2210, 2261, 2326, 2341, 2418, 2471, 2507, 2533, 2596, 2616, 2684, 2723, 2740, 2786, 2811, 2822, 2857, 2928, 2949, 2977, 3254, 3340, 3374, 3737, 4213, 4233, 4265, 4302, 4347, 4372, 4425, 4443], 'Dr.': [1521, 1527, 1594, 1669, 1857, 1877, 1904], 'Green': [1523], '(Harvard': [1524], 'University)': [1525], 'Sonenberg': [1529], '(Sloan-Kettering).': [1530], 'expressing': [1535], 'rat': [1536], 'GHR': [1537], 'containing': [1538, 1747, 1773, 1820, 2122, 2663, 2936, 3966, 4368], 'half': [1541], 'cytoplasmic': [1544], '(CHO-GHR)': [1546], '(Karolinska': [1552], 'Institute,': [1553], 'Stockholm,': [1554], 'Sweden)': [1555], '(Hagedorn': [1559], 'Laboratory,': [1560], 'Gentofte,': [1561], 'Denmark)': [1562], '(26Billestrup': [1563], 'Allevato': [1565], 'Moldrup': [1569], 'Nielsen': [1571], 'J.H.': [1572], 'Soc.': [1574], 'Exp.': [1575], 'Med.': [1577], '206:': [1579], '205-209Crossref': [1580], '(14)': [1583], 'Human': [1586], 'embryonic': [1587], 'kidney': [1588], '293T': [1589, 1738, 2738, 4341, 4419], 'Lazar': [1596], '(University': [1597, 1860, 1880, 1907], 'Pennsylvania).': [1599], 'Recombinant': [1600, 1676, 2499], 'human': [1601], 'Eli': [1606], 'Lilly.': [1607], 'Culture': [1608], 'media': [1609, 1793], 'purchased': [1611, 1622, 1634, 1644, 1653, 1679, 1693, 1718, 1725, 1896, 1963, 1989, 2023], 'from': [1612, 1623, 1630, 1635, 1645, 1668, 1680, 1694, 1709, 1719, 1726, 1733, 1856, 1897, 1964, 1990, 2024, 2394, 2678, 3687, 4094, 4215, 4340, 4418], 'Irvine': [1613], 'Scientific.': [1614], 'Calf': [1615], 'fetal': [1618, 1775], 'calf': [1619, 1753, 1776], 'Life': [1624, 1711], 'Technologies,': [1625, 2206], 'Inc.,': [1626], '(BSA,': [1628], 'CRG7)': [1629], 'Intergen.': [1631], 'Wortmannin': [1632], 'Calbiochem.': [1636], 'LY294002,': [1637, 3257], 'lithium': [1638], 'chloride,': [1639], 'sodium': [1641, 2096, 2100, 2258], 'orthovanadate': [1642, 2838], 'Sigma': [1646], 'Chemical': [1647], 'Co.,': [1648], 'fromRoche': [1654], 'Molecular': [1655, 1696], 'Biochemicals.': [1656], 'MEK': [1658, 3192, 3292], 'inhibitor': [1659, 1689, 2808, 3213, 3293, 3380, 3710], 'PD098059': [1660, 3294], 'peptide': [1664, 1950, 1985, 2013, 2303, 2308, 2391, 2400, 3651, 3965], 'gifts': [1667, 1855], 'Saltiel': [1671, 3154, 3980], '(Pfizer,': [1672], 'Ann': [1673], 'Arbor,': [1674], 'MI).': [1675], 'England': [1682, 1992], 'BioLabs.': [1683, 1993], 'Aprotinin,': [1684], 'leupeptin,': [1685], 'Complete®': [1687], 'protease': [1688, 2807], 'mixture': [1690, 2352], '(EDTA-free)': [1691], 'Roche': [1695], 'Biochemicals': [1697], 'used': [1699, 3002, 4296], 'according': [1700], "supplier's": [1703], 'instructions.': [1704], '[α-32P]dATP': [1705], '[γ-32P]ATP': [1707, 2313, 2504, 3975, 4221], 'PerkinElmer': [1710], 'Sciences.': [1712], 'ECL': [1714], 'detection': [1715], 'system': [1716], 'Amersham': [1720], 'Pharmacia': [1721], 'Biotech.': [1722], 'Luciferin': [1723], 'Promega': [1727], 'β-galactosidase': [1729, 2886, 2966, 2980], 'chemiluminescence': [1730], 'reagents': [1731], 'Tropix.': [1734], 'preadipocytes': [1736], 'grown': [1741, 1768], "Dulbecco's": [1743], 'modified': [1744], "Eagle's": [1745], 'medium': [1746, 1772, 1819, 2935], '4.5': [1748], 'g/liter': [1749], 'glucose': [1750], '8%': [1752], 'atmosphere': [1757, 1784], '10%': [1759, 1774], 'CO2/90%': [1760], 'air': [1761, 1788], '37': [1763, 1790, 2845], '°C.': [1764, 1791, 2467, 2815], 'CHO-GHR': [1765, 2852], "Ham's": [1770], 'F-12': [1771], '0.5': [1779, 2256, 2300], 'mg/ml': [1780, 2301], 'G418': [1781], '5%': [1786], 'CO2/95%': [1787], 'All': [1792], 'supplemented': [1795], '1': [1797, 2098, 2123, 2126, 2226, 2229, 2242, 2245, 2297, 2496, 2800, 2803, 2842, 2961, 3232, 3265, 3459, 4313], 'mml-glutamine,': [1798], '100': [1799, 1802, 2236, 2311, 2334], 'units/ml': [1800], 'penicillin,': [1801], 'mg/μl': [1803], 'streptomycin,': [1804], '0.25': [1806], 'μg/ml': [1807, 2132, 2253], 'amphotericin.': [1808], 'Prior': [1809], 'treatment,': [1811], 'incubated': [1814, 1829, 2602, 2823, 4219, 4234, 4350, 4426, 4444], 'overnight': [1815, 2600], 'appropriate': [1818, 4254], '1%': [1821, 2937], 'BSA': [1822, 2938], 'instead': [1823, 4297], 'serum,': [1825], 'then': [1826], 'without': [1832, 2772, 2826, 2892, 4427], '500': [1835], 'ng/ml': [1836], '(22': [1837], 'nm)': [1838], 'indicated.': [1840, 2946, 3007], 'Plasmids': [1841], 'encoding': [1842, 2895], 'driven': [1846], 'CMV': [1849], '(CMV-LAP': [1851], 'CMV-LIP)': [1853], 'Geneva)': [1862], 'courtesy': [1863], '(Vanderbilt': [1867], 'University).': [1868], 'plasmid': [1870, 1900, 2887, 2894], 'RSV-β': [1871], 'galactosidase': [1872], '(RSV-β-gal)': [1873], 'Uhler': [1879], 'Michigan).': [1882], 'CMV-GSK-3': [1883, 2773], 'S9A': [1884, 2774, 2901], 'Roach': [1890], '(Indiana': [1891], 'University),': [1892], 'pcDNA3.1': [1894, 2918], 'CLONTECH.': [1898], 'wt-fos-Luc,': [1901], 'W.': [1905, 1914], 'Wharton': [1906, 1913], 'South': [1909], 'Florida)': [1910], '(27Harvat': [1911], 'B.L.': [1912], 'Cell': [1915, 2028, 2947], 'Diff.': [1917], '955-964PubMed': [1920], '379': [1924], 'mouse': [1928], 'immediately': [1931], '5′': [1932], 'cloned': [1938], 'upstream': [1939], 'luciferase': [1942, 2964, 2975], 'gene.': [1943], 'Specific': [1944], 'rabbit': [1945, 2459], 'polyclonal': [1946, 1979], 'antibodies': [1947, 1970, 1980, 1995, 2148], 'against': [1948, 1982, 1996, 2149, 2191, 2446], 'corresponding': [1951, 1999, 2014, 2189, 2915], 'amino': [1953, 2001, 2016], 'acids': [1954, 2002, 2017], '278–295': [1955], 'C': [1958], 'terminus': [1959], 'Santa': [1965], 'Cruz': [1966], 'Biotechnology,': [1967], 'Inc.': [1968, 2027], 'Polyclonal': [1969, 1994], 'recognize': [1972], 'phosphorylated': [1973, 2006, 3654, 3744, 3904, 4103, 4245], 'Ser-473': [1974, 3656], '(anti-P-Akt),': [1977], 'made': [1981], '466–479': [1986], '(anti-Akt)': [1987], 'oligopeptide': [1998], '16–26': [2003], 'GSK-3α': [2005, 4037], 'Ser-21': [2008, 4040, 4104], '(anti-P-GSK-3)': [2009], '203–219': [2018], '(anti-GSK-3)': [2021], 'Upstate': [2025], 'Biotechnology': [2026], 'lysis': [2029, 2109, 2953], 'immunoblotting': [2031, 2146, 4091], 'performed': [2035, 4271], 'previously': [2037, 2157, 2539, 2620, 2685], 'described': [2038, 2158, 2540, 2612, 2619, 2686], 'follows:': [2075], 'confluent': [2076], '100-mm': [2080], 'plates': [2081], 'washed': [2083, 2211, 2360, 2419, 2472], 'phosphate-buffered': [2085, 2213], 'saline': [2086, 2214], 'vanadate': [2088], '(10': [2089], 'mm': [2090, 2095, 2099, 2112, 2117, 2124, 2127, 2222, 2227, 2232, 2237, 2243, 2246, 2249, 2257, 2290, 2295, 2298, 2335, 2366, 2428, 2433, 2436, 2489, 2494, 2497, 2793, 2796, 2801], 'Tris': [2091], '(pH': [2092, 2224, 2292, 2430, 2491, 2798], '7.4),': [2093, 2225, 2293, 2492], '150': [2094, 2432], 'phosphate,': [2097, 2957], 'vanadate)': [2101], 'scraped': [2103, 2421], '0.3': [2105], 'ml': [2106], 'L-RIPA': [2108], 'buffer': [2110, 2220, 2426, 2479, 2487, 2791, 2954], '(50': [2111, 2221, 2427, 2488], 'Hepes,': [2113], 'pH': [2114], '7.0,': [2115], '250': [2116], 'NaCl,': [2118, 2434, 2794], '0.5%': [2119, 2239, 2424, 2438, 2477], 'Triton': [2120, 2240, 2959], 'X-100)': [2121], 'Na3VO4,': [2125], 'phenylmethylsulfonyl': [2128, 2250], 'fluoride,': [2129, 2251], '10': [2131, 2231, 2252, 2268, 2294, 2493], 'each': [2133, 2991], 'aprotinin': [2135], 'leupeptin.': [2137], 'Whole': [2138], 'lysates': [2140, 2781, 2821, 2948, 4093], '(35–50': [2141], 'μg)': [2142, 2765, 2769, 2882], 'analyzed': [2144], 'using': [2147, 2187, 2397, 2742, 2788, 2970, 3644, 4376], 'phospho-Akt': [2150], 'phospho-GSK-3.': [2152], 'Blots': [2153], 'reprobed': [2155], '(8Hodge': [2159], 'antibody': [2190, 2445, 3646, 4099], 'GSK-3.': [2194, 3951, 4229], 'apparentM': [2196], 'r': [2197], 'based': [2199], 'prestained': [2201], 'molecular': [2202], 'weight': [2203], 'standards': [2204], '(Life': [2205], 'Inc.).': [2207], 'lysed': [2216], 'extraction': [2219], 'Hepes': [2223, 2291, 2490, 2797], 'EGTA,': [2228, 2437], 'mmEDTA,': [2230], 'β-glycerophosphate,': [2233], '5': [2234, 2337, 3669, 4112], 'mmNa2PO4,': [2235], 'KCl,': [2238], 'X-100,': [2241, 2960], 'dithiothreitol,': [2244, 2299], 'benzamidine,': [2247], '0.1': [2248], 'aprotinin,': [2254], 'vanadate).': [2259], 'Samples': [2260], 'centrifuged': [2262], '15,000': [2264], '×': [2265, 2854], 'g': [2266], 'min.': [2269, 4032], 'activity': [2271, 2967, 3817, 3953, 4011, 4026, 4286], 'measured': [2273, 2380, 2969, 3957], 'supernatant': [2276], '(8': [2277, 2775], 'μg': [2278], 'protein)': [2280], 'final': [2283], 'volume': [2284, 2457], '25': [2286], 'μl': [2287, 2484], '50': [2289, 2483], 'MgCl2,': [2296, 2495], 'synthetic': [2302, 3964], '(RRAAEELDSRAG(p)SPQL)': [2304], 'negative': [2306, 2389], 'control': [2307, 2390, 3431], '(RRAAEELDSRAGAPQL),': [2309], 'μm': [2312], '(1000': [2314], 'cpm/pmol).': [2315], 'After': [2316, 2468, 2509], 'incubation': [2317, 2513, 2933, 4269], '15': [2319, 3688, 4013], 'min': [2320, 2411, 2511, 2656, 3670, 3691, 4014, 4113], '30': [2322, 2515, 2655, 3297, 4031], '°C,': [2323, 2516], 'reactions': [2325, 2652], 'terminated': [2327], '(5': [2332, 2452], 'μl)': [2333, 2348, 2453], 'EDTA,': [2336, 2802], 'mmATP,': [2338], 'tubes': [2340], 'placed': [2342], 'ice.': [2344], 'An': [2345, 2577], 'aliquot': [2346, 2578], '(20': [2347], 'reaction': [2351, 2518], 'spotted': [2354], 'onto': [2355], 'Whatman': [2356], 'p81': [2357], 'phosphocellulose': [2358], 'paper,': [2359], '175': [2365], 'phosphoric': [2367], 'acid': [2368], 'total': [2371, 3706], '20': [2373, 2795], 'min,': [2374], 'air-dried,': [2375], '32P': [2377, 2385], 'incorporation': [2378, 2386], 'liquid': [2382], 'scintillation': [2383], 'counting.': [2384], 'subtracted': [2393], 'values': [2395, 2976], 'obtained': [2396, 3251], 'substrate.': [2401], 'Results': [2402], 'expressed': [2404], 'nanomoles': [2406], 'phosphate': [2408, 2744, 2862], 'incorporated': [2409], 'per': [2410, 2412, 2920], 'mg': [2413], 'protein.': [2415], 'RIPA': [2423, 2476], 'SDS': [2425, 2478], 'Tris-HCl': [2429], '7.5),': [2431], '2': [2435, 2463, 3720, 3785], 'SDS).': [2439], 'immunoprecipitated': [2442, 4214], '(or': [2454], 'equivalent': [2456], 'non-immune': [2460, 4293], 'serum)': [2461], 'h': [2464, 2778, 2843, 2941], '4': [2466, 3237, 3463, 4278], 'centrifugation,': [2469], 'pellets': [2470], 'times': [2474, 2606], 'resuspended': [2481], 'dithiothreitol).': [2498], '(15': [2501], 'units)': [2502, 4437], '(500': [2505], 'μCi/μmol)': [2506], 'added.': [2508], '40': [2510], 'stopped': [2520], 'boiling': [2522], 'samples': [2524], 'presence': [2527, 2834, 2906, 3455, 3474, 3519, 3973, 4224, 4239, 4309, 4357], 'sample': [2529, 2581], 'buffer.': [2530], 'separated': [2534, 2724], '15%': [2536], 'SDS-PAGE': [2537, 3024], 'determined': [2574], 'autoradiography.': [2576, 2731], 'subjected': [2583], 'immunoblot': [2585], 'analysis': [2586, 2733], 'immunoprecipitate.': [2592], 'Confluent': [2593], 'deprived': [2597, 2929], 'indicated': [2605, 3018], 'vehicle': [2610], 'above.': [2613], 'Nuclear': [2614], 'extracts': [2615, 4339, 4417, 4442], 'prepared': [2617, 2787, 2950], 'Binding': [2651], 'proceeded': [2653], 'room': [2658], 'temperature': [2659], 'labeled': [2661, 4300], 'oligonucleotides': [2662], 'flanking': [2669], 'SRE': [2670], '(wt': [2671], 'C/EBP-SRE)': [2672], '422/aP2': [2680], '(aP2-C/EBP)': [2682], 'Complexes': [2717], 'formed': [2718], 'nondenaturing': [2726], '7%': [2727], 'PAGE': [2728], 'followed': [2729], 'LIP,': [2737, 3184, 4185, 4334], 'transfected': [2741, 2859], 'calcium': [2743, 2861], 'coprecipitation': [2745, 2863], '(28Chen': [2746, 2864], 'D.': [2747, 2865], 'Okayama': [2748, 2866], '7:': [2754, 2872], '2745-2752Crossref': [2755, 2873], '(4815)': [2758, 2876], 'plasmids': [2762], 'CMV-LAP': [2763, 2910], '(1': [2764, 2853, 2912], 'CMV-LIP': [2767], '(l': [2768], 'μg).': [2776], '48': [2777], 'later,': [2779], 'enriched': [2782, 2820], 'high': [2789], 'salt': [2790], '(420': [2792], '7.9),': [2799], 'mmEGTA,': [2804], '50%': [2805], 'glycerol,': [2806], 'mixture)': [2809], 'stored': [2812], '−80': [2814], 'some': [2817], 'experiments,': [2818], '200': [2827, 4436], 'units': [2828], 'phosphatase,': [2831], 'absence': [2836, 2908, 3517, 4226, 4274, 4307, 4353], '(30': [2839, 3215], 'mm),': [2840], '°C': [2846], 'prior': [2847, 2942, 3217, 3261, 3299], 'EMSA': [2849, 4375], 'immunoblotting.': [2851], '105cells/35-mm': [2855], 'well)': [2856], 'transiently': [2858], 'wt-fos-Luc': [2880], '(0.4': [2881], 'RSV': [2885], '(0.1': [2888], 'μg),': [2889, 2903], '(GSK-3': [2900], '0.8': [2902], 'ng)': [2913], 'amounts': [2916], 'vector': [2919], '35-mm': [2921], 'well.': [2922], 'Twenty-four': [2923], 'hours': [2924], 'after': [2925], 'transfection,': [2926], '18': [2940], 'treatment': [2944, 3219, 4116], 'reporter': [2952], '(100': [2955], 'mmpotassium': [2956], '0.2%': [2958], 'mmdithiothreitol),': [2962], 'Opticomp': [2972], 'luminometer.': [2973], 'normalized': [2978], 'Each': [2982], 'condition': [2983], 'tested': [2985, 3186], 'duplicate': [2987], 'triplicate': [2989], 'experiment.': [2992], 'variance': [2995], 'factorial': [2997], 'Scheffe': [2998], 'F': [2999], 'test': [3000], 'analyze': [3004], 'data': [3005, 3543], 'causes': [3009], 'increased': [3021, 3421, 3484], 'mobility': [3022], 'MAPKs': [3062], 'ERK1': [3063], 'ERK2': [3065], 'several': [3067, 3829], 'types,': [3069], '(29Ridderstrale': [3073], 'Tornqvist': [3075], 'Biochem.': [3077, 3872, 3888], 'Biophys.': [3078], 'Res.': [3079], 'Commun.': [3080], '203:': [3082], '306-310Crossref': [3083], '(57)': [3086], '30VanderKuur': [3089], 'Butch': [3091], 'Waters': [3093], 'S.B.': [3094], 'Pessin': [3095], 'J.E.': [3096], 'K.-L.': [3098], '4301-4307Crossref': [3104], '(88)': [3107], '31Winston': [3110], 'L.A.': [3111], 'Bertics': [3112], 'P.J.': [3113, 3605], '4747-4751Abstract': [3119], '32Moller': [3126], 'Hansson': [3128], 'Enberg': [3130], 'B.': [3131], 'Lobie': [3132], 'P.E.': [3133], '23403-23408Abstract': [3141], '33Campbell': [3148], 'Pang': [3150], 'Miyasaka': [3152], 'A.R.': [3155, 3981], '6074-6080Abstract': [3163], 'To': [3170], 'evaluate': [3171], 'either': [3173], 'pathways': [3177], 'we': [3185], 'effect': [3188], 'inhibitors': [3193], 'promote': [3200, 4180], 'Treatment': [3206, 3289, 3481, 3998], 'wortmannin': [3214, 3503, 3527, 3711, 4134], 'min)': [3216, 3223, 3298], '(60': [3222], 'markedly': [3224], 'impaired': [3225], '(Fig.': [3231, 3264, 3458, 3671, 3692, 3719, 3784, 4141, 4277], 'A,': [3233, 3266, 3673, 3694, 3721, 4248, 4279, 4338], 'band': [3234, 3267, 3429, 3435, 4410], 'b,': [3235, 3268, 3436, 3461], 'lane': [3236, 3239, 3269, 3272, 3437, 3462, 3465, 4119, 4249, 4261, 4280, 4412], 'versus': [3238, 3271, 3464, 4146], '2)': [3240, 4281, 4359, 4402], '(not': [3243, 3313], 'shown).': [3244], 'Similar': [3245, 3332], 'inhibition': [3246, 3469, 3949, 4008, 4019, 4156, 4167], 'treated': [3255], 'another': [3258], '8': [3270], '6).': [3273, 4262], 'Taken': [3274, 3797], 'together': [3275], 'results': [3277, 3800, 4046, 4149, 4317], 'suggest': [3278, 3558], '(40': [3295], 'μm,': [3296], 'did': [3302, 4287], 'not': [3303, 3523, 3531, 3751, 3763, 4288, 4303, 4333], 'interfere': [3304], 'shown),': [3314, 3524], 'indicating': [3315, 3525, 4282], 'MEK-ERK': [3318, 3760], 'pathway': [3319, 3535, 3551, 3761], 'unlikely': [3321], 'major': [3325], 'contributor': [3326], 'this': [3328], 'observed': [3341, 3492], 'throughout': [3346], 'studies.': [3348], 'Because': [3349, 4166], 'lead': [3356], 'involvement': [3363], 'examined.': [3372], 'Cells': [3373], 'pretreated': [3375, 3738], 'LiCl,': [3377], '(34Klein': [3381], 'Melton': [3383], 'D.A.': [3384, 4054], '93:': [3393], '8455-8459Crossref': [3394], '(2068)': [3397], '35Stambolic': [3400], 'V.': [3401], 'Ruel': [3402], 'Woodgett': [3404], 'J.R.': [3405, 3867, 3885], 'Curr.': [3406], '1664-1668Abstract': [3410], 'slightly': [3420], 'intensity': [3423], 'rapidly': [3426, 3445], 'migrating': [3427, 3446], '(Fig.1': [3433], 'B,': [3434, 3674, 3695, 3754, 4118, 4127, 4143, 4260, 4416], '3).': [3438, 4315], 'Notably,': [3439], 'shift': [3442], 'further': [3451], 'enhanced': [3452], 'LiCl': [3457, 3483, 3505, 3529], 'B,band': [3460], '2),': [3466, 4120], 'favors': [3472], 'similarly': [3488], 'untreated': [3498], 'contrast,': [3501], 'neither': [3502], 'nor': [3504], 'altered': [3506, 3752], 'pattern': [3508], 'ERK-1': [3512], '-2': [3514], '(data': [3522], 'do': [3530], 'affect': [3532], 'MAPK': [3534], 'under': [3536], 'conditions': [3538], 'experiments.': [3541], 'consistent': [3545, 3724], 'utilizing': [3548], 'involved': [3563, 3764], 'downstream': [3564, 3570, 3794, 3813, 3905], 'PI3K.': [3566, 3733, 3815, 4165], 'effector': [3571], '(36Franke': [3574], 'T.F.': [3575], 'Yang': [3576], 'S.I.': [3577], 'Chan': [3578], 'T.O.': [3579], 'Datta': [3580], 'Kazlauskas': [3582], 'Morrison': [3584], 'D.K.': [3585], 'Kaplan': [3586], 'D.R.': [3587, 4056], 'Tsichlis': [3588], 'P.N.': [3589], '81:': [3592], '727-736Abstract': [3593], '(1820)': [3599], '37Burgering': [3602], 'B.M.T.': [3603], 'Coffer': [3604], '376:': [3608], '599-602Crossref': [3609], '(1874)': [3612], '38Kohn': [3615], 'A.D.': [3616], 'Kovacina': [3617], 'K.S.': [3618], 'Roth': [3619], 'R.A.': [3620], '14:': [3624], '4288-4295Crossref': [3625], '(318)': [3628], 'stimulate': [3636], 'examined': [3641], 'immunoblotting,': [3643], 'specifically': [3648, 4101], 'recognizes': [3649, 4102], '(anti-P-Akt).': [3657], 'found': [3660, 4080], 'amount': [3664, 4084], 'Ser-phosphorylated': [3666], 'within': [3668, 4012, 4030, 4111], '2,': [3672, 3693, 4439], 'andC,': [3675], 'upper': [3676, 3698, 4409], 'panels,': [3677, 3699], 'lanes': [3678, 3700, 3722, 3755, 3787, 4128, 4144], '1,2).': [3679], 'stimulation': [3681], 'subsided': [3686, 4122], '60': [3690], 'C,': [3697, 3786], '3–6).': [3701], 'lower': [3703], 'panels': [3704], 'show': [3705], 'Akt.': [3707, 3769, 3796], 'completely': [3712], 'blocked': [3713], '7–12),': [3723, 3756, 3788], 'being': [3730], 'dependent': [3731], 'When': [3734, 4230, 4292], 'PD098059,': [3740], 'appearance': [3742], '(Fig.2': [3753], 'failed': [3775], 'expected,': [3790, 4131], 'because': [3791, 4187], 'together,': [3798], 'that,': [3802], 'inhibited': [3819], 'types': [3831], '(39Cross': [3832, 3908], 'M.J.': [3833, 3841, 3909, 3917, 3977], 'Stewart': [3834, 3910], 'Hodgkin': [3836, 3912], 'M.N.': [3837, 3913], 'Kerr': [3838, 3914], 'Wakelam': [3840, 3916], '25352-25355Abstract': [3847, 3923], '(251)': [3855, 3931], '40Hurel': [3858], 'S.J.': [3859, 3871], 'Rockford': [3860], 'J.J.': [3861], 'Borthwick': [3862], 'A.C.': [3863], 'Wells': [3864], 'A.M.': [3865], 'Vandenheede': [3866, 3884], 'Turnbull': [3868], 'D.M.': [3869], 'Yeaman': [3870], '320:': [3875], '871-877Crossref': [3876], '(83)': [3879], '41Saito': [3882], 'Cohen': [3886, 4057], '303:': [3891], '27-31Crossref': [3892], '(126)': [3895], 'inactivated': [3900], 'it': [3902, 3935], 'Hence,': [3934], 'would': [3936, 3945], 'predicted': [3938], 'its': [3959], 'phosphorylate': [3962], 'consensus': [3969, 4195], 'sequence': [3970, 4196], '(42Brady': [3976], 'Bourbonais': [3978], 'F.J.': [3979], '14063-14066Abstract': [3987], '(111)': [3995], 'resulted': [4004], '30–40%': [4007], '(Fig.3': [4015, 4117], 'A).': [4016], 'transient,': [4023], 'returned': [4027], 'baseline': [4029], 'Akt-dependent': [4033], 'isoform': [4038], 'GSK-3β': [4043], 'Ser-9': [4045], 'partial': [4048], '(43Cross': [4053], 'Alessi': [4055], 'Andjelkovich': [4059], 'Hemmings': [4061], 'B.A.': [4062], '378:': [4065], '785-789Crossref': [4066], '(4334)': [4069], 'Consistent': [4072], 'serine-phosphorylated': [4086], 'detected': [4089, 4266, 4304], 'GSK-3α.': [4106], 'evident': [4110], 'progressively': [4123], '(15–90': [4124], 'min)(Fig.': [4125], '3': [4126, 4142], '3-6).': [4129], 'As': [4130], 'pretreatment': [4132], '7–12': [4145], '1–6).': [4147], 'stimulates': [4153], 'most': [4159], 'likely': [4160], 'mechanism': [4163], 'involving': [4164], 'might': [4172], 'both': [4188], 'contain': [4192], 'putative': [4194], 'possibility': [4200], 'substrate(s)': [4207], 'tested.': [4209], 'recombinant': [4228], 'anti-C/EBPβ': [4231], 'immunoprecipitates': [4232], '[γ-32P]ATP,': [4241], 'autoradiography': [4242], 'revealed': [4243], '(Fig.4': [4247], '4)': [4250], 'sizes': [4253], '(Fig.5': [4259], 'No': [4263], 'phosphoproteins': [4264], 'other': [4284], 'co-precipitate': [4289], 'anti-C/EBPβ,': [4299], '(lanes': [4312, 4428, 4438, 4446, 4451], 'GSK-3.Figure': [4328], '5Dephosphorylation': [4329], 'but': [4332], 'mixed': [4348], '(lane': [4354, 4358, 4401], '1)': [4355], 'antiserum': [4361], 'specific': [4362], '(anti-β),': [4365], 'identified': [4373], 'wt': [4377, 4455], 'C/EBP-SRE': [4378, 4456], 'probe.': [4380], 'Migration': [4381], 'representing': [4384], '(LAP/LAP),': [4387], '(LIP/LIP),': [4390], 'LAP/LIP': [4392], 'heterodimers': [4393], '(LAP/LIP)': [4394], '(left': [4397], 'margin).': [4398], 'arrow': [4400], 'marks': [4403], 'supershift': [4404], 'anti-C/EBPβ.': [4406], 'faint': [4408], '1represents': [4413], 'SRF.': [4415], '1,3,': [4429], '5)': [4430], '(AP,': [4435], '4,6).': [4440], 'separately': [4445], '1–4)': [4447], 'combination': [4450], '5–6)': [4452], 'probe': [4457]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2119816993', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-09T22:20:12.665943', 'created_date': '2016-06-24'}