Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2118918019', 'doi': 'https://doi.org/10.1038/cmi.2015.95', 'title': 'Molecular mechanisms regulating NLRP3 inflammasome activation', 'display_name': 'Molecular mechanisms regulating NLRP3 inflammasome activation', 'publication_year': 2015, 'publication_date': '2015-11-09', 'ids': {'openalex': 'https://openalex.org/W2118918019', 'doi': 'https://doi.org/10.1038/cmi.2015.95', 'mag': '2118918019', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/26549800', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4786634'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/cmi.2015.95', 'pdf_url': 'https://www.nature.com/articles/cmi201595.pdf', 'source': {'id': 'https://openalex.org/S19143454', 'display_name': 'Cellular and Molecular Immunology', 'issn_l': '1672-7681', 'issn': ['1672-7681', '2042-0226'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nature.com/articles/cmi201595.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055011319', 'display_name': 'Eun‐Kyeong Jo', 'orcid': 'https://orcid.org/0000-0001-7191-0587'}, 'institutions': [{'id': 'https://openalex.org/I196345858', 'display_name': 'Chungnam National University', 'ror': 'https://ror.org/0227as991', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I196345858']}], 'countries': ['KR'], 'is_corresponding': True, 'raw_author_name': 'Eun-Kyeong Jo', 'raw_affiliation_strings': ['Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea', 'institution_ids': ['https://openalex.org/I196345858']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100671861', 'display_name': 'Jin Kyung Kim', 'orcid': 'https://orcid.org/0000-0002-2051-5787'}, 'institutions': [{'id': 'https://openalex.org/I196345858', 'display_name': 'Chungnam National University', 'ror': 'https://ror.org/0227as991', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I196345858']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jin Kyung Kim', 'raw_affiliation_strings': ['Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea', 'institution_ids': ['https://openalex.org/I196345858']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035141905', 'display_name': 'Dong–Min Shin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I196345858', 'display_name': 'Chungnam National University', 'ror': 'https://ror.org/0227as991', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I196345858']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Dong-Min Shin', 'raw_affiliation_strings': ['Infection Signaling Network Research Center, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea'], 'affiliations': [{'raw_affiliation_string': 'Infection Signaling Network Research Center, Chungnam National University School of Medicine, Daejeon, 301-747, South Korea', 'institution_ids': ['https://openalex.org/I196345858']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052633242', 'display_name': 'Chihiro Sasakawa', 'orcid': 'https://orcid.org/0000-0002-6919-1832'}, 'institutions': [{'id': 'https://openalex.org/I4210099339', 'display_name': 'Chiba University Hospital', 'ror': 'https://ror.org/0126xah18', 'country_code': 'JP', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210099339']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Chihiro Sasakawa', 'raw_affiliation_strings': ['Medical Mycology Research Center, Chiba University, Chiba, 260-8673, Japan'], 'affiliations': [{'raw_affiliation_string': 'Medical Mycology Research Center, Chiba University, Chiba, 260-8673, Japan', 'institution_ids': ['https://openalex.org/I4210099339']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5055011319'], 'corresponding_institution_ids': ['https://openalex.org/I196345858'], 'apc_list': {'value': 3690, 'currency': 'EUR', 'value_usd': 4790, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 7.225, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1059, 'citation_normalized_percentile': {'value': 0.596046, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '13', 'issue': '2', 'first_page': '148', 'last_page': '159'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11078', 'display_name': 'Molecular Mechanisms of Inflammasome Activation and Regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11078', 'display_name': 'Molecular Mechanisms of Inflammasome Activation and Regulation', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11892', 'display_name': 'Diagnosis and Management of Kawasaki Disease', 'score': 0.9706, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/aim2', 'display_name': 'AIM2', 'score': 0.57189035}, {'id': 'https://openalex.org/keywords/inflammasome', 'display_name': 'Inflammasome', 'score': 0.570946}, {'id': 'https://openalex.org/keywords/nlrp3', 'display_name': 'NLRP3', 'score': 0.539499}, {'id': 'https://openalex.org/keywords/inflammation', 'display_name': 'Inflammation', 'score': 0.529439}, {'id': 'https://openalex.org/keywords/pyroptosis', 'display_name': 'Pyroptosis', 'score': 0.4726661}, {'id': 'https://openalex.org/keywords/pyrin-domain', 'display_name': 'Pyrin domain', 'score': 0.42815495}], 'concepts': [{'id': 'https://openalex.org/C2777209026', 'wikidata': 'https://www.wikidata.org/wiki/Q412405', 'display_name': 'Inflammasome', 'level': 3, 'score': 0.993616}, {'id': 'https://openalex.org/C187831198', 'wikidata': 'https://www.wikidata.org/wiki/Q18034187', 'display_name': 'AIM2', 'level': 4, 'score': 0.57189035}, {'id': 'https://openalex.org/C139964883', 'wikidata': 'https://www.wikidata.org/wiki/Q14901964', 'display_name': 'Caspase 1', 'level': 4, 'score': 0.565145}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5533349}, {'id': 'https://openalex.org/C17172800', 'wikidata': 'https://www.wikidata.org/wiki/Q7263707', 'display_name': 'Pyroptosis', 'level': 4, 'score': 0.4726661}, {'id': 'https://openalex.org/C98539663', 'wikidata': 'https://www.wikidata.org/wiki/Q220599', 'display_name': 'Cytosol', 'level': 3, 'score': 0.45900744}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.4423283}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.43793595}, {'id': 'https://openalex.org/C139174496', 'wikidata': 'https://www.wikidata.org/wiki/Q24725912', 'display_name': 'Pyrin domain', 'level': 4, 'score': 0.42815495}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41327688}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33650777}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3047846}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.108174324}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D058847', 'descriptor_name': 'Inflammasomes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000071199', 'descriptor_name': 'NLR Family, Pyrin Domain-Containing 3 Protein', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058847', 'descriptor_name': 'Inflammasomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053583', 'descriptor_name': 'Interleukin-1beta', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D053583', 'descriptor_name': 'Interleukin-1beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071199', 'descriptor_name': 'NLR Family, Pyrin Domain-Containing 3 Protein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000071199', 'descriptor_name': 'NLR Family, Pyrin Domain-Containing 3 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/cmi.2015.95', 'pdf_url': 'https://www.nature.com/articles/cmi201595.pdf', 'source': {'id': 'https://openalex.org/S19143454', 'display_name': 'Cellular and Molecular Immunology', 'issn_l': '1672-7681', 'issn': ['1672-7681', '2042-0226'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4786634', 'pdf_url': 'https://europepmc.org/articles/pmc4786634?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786634', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/26549800', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/cmi.2015.95', 'pdf_url': 'https://www.nature.com/articles/cmi201595.pdf', 'source': {'id': 'https://openalex.org/S19143454', 'display_name': 'Cellular and Molecular Immunology', 'issn_l': '1672-7681', 'issn': ['1672-7681', '2042-0226'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.85, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 139, 'referenced_works': ['https://openalex.org/W1524848610', 'https://openalex.org/W1529674879', 'https://openalex.org/W1541195059', 'https://openalex.org/W1542609738', 'https://openalex.org/W1559677484', 'https://openalex.org/W1560867514', 'https://openalex.org/W1574997543', 'https://openalex.org/W1579701530', 'https://openalex.org/W1593143946', 'https://openalex.org/W1636793459', 'https://openalex.org/W1680053970', 'https://openalex.org/W1756750202', 'https://openalex.org/W1836365179', 'https://openalex.org/W1877034389', 'https://openalex.org/W1894792769', 'https://openalex.org/W1904832534', 'https://openalex.org/W1927491384', 'https://openalex.org/W1964162666', 'https://openalex.org/W1966625479', 'https://openalex.org/W1967285776', 'https://openalex.org/W1968564077', 'https://openalex.org/W1972483153', 'https://openalex.org/W1975012711', 'https://openalex.org/W1976143672', 'https://openalex.org/W1978274182', 'https://openalex.org/W1978602689', 'https://openalex.org/W1979991507', 'https://openalex.org/W1982535405', 'https://openalex.org/W1984367086', 'https://openalex.org/W1985538633', 'https://openalex.org/W1987329700', 'https://openalex.org/W1988230895', 'https://openalex.org/W1989551786', 'https://openalex.org/W1994167951', 'https://openalex.org/W1994473516', 'https://openalex.org/W1996087219', 'https://openalex.org/W1996758156', 'https://openalex.org/W1997572777', 'https://openalex.org/W1998639445', 'https://openalex.org/W1999224782', 'https://openalex.org/W1999276471', 'https://openalex.org/W2001160691', 'https://openalex.org/W2001946532', 'https://openalex.org/W2005233485', 'https://openalex.org/W2009004909', 'https://openalex.org/W2009800174', 'https://openalex.org/W2010508038', 'https://openalex.org/W2011344898', 'https://openalex.org/W2014054401', 'https://openalex.org/W2014769550', 'https://openalex.org/W2014886061', 'https://openalex.org/W2015129508', 'https://openalex.org/W2018563185', 'https://openalex.org/W2018607502', 'https://openalex.org/W2022078450', 'https://openalex.org/W2022130951', 'https://openalex.org/W2023954822', 'https://openalex.org/W2025355874', 'https://openalex.org/W2025673880', 'https://openalex.org/W2026400708', 'https://openalex.org/W2029456306', 'https://openalex.org/W2036974885', 'https://openalex.org/W2042767581', 'https://openalex.org/W2044676100', 'https://openalex.org/W2045969462', 'https://openalex.org/W2046440869', 'https://openalex.org/W2047119613', 'https://openalex.org/W2047923753', 'https://openalex.org/W2048030072', 'https://openalex.org/W2049267620', 'https://openalex.org/W2049893029', 'https://openalex.org/W2051303794', 'https://openalex.org/W2051658957', 'https://openalex.org/W2052622892', 'https://openalex.org/W2054571187', 'https://openalex.org/W2055727949', 'https://openalex.org/W2058690999', 'https://openalex.org/W2063894714', 'https://openalex.org/W2064173000', 'https://openalex.org/W2064456932', 'https://openalex.org/W2064741210', 'https://openalex.org/W2067101371', 'https://openalex.org/W2067406680', 'https://openalex.org/W2069633550', 'https://openalex.org/W2071766782', 'https://openalex.org/W2073875167', 'https://openalex.org/W2076062022', 'https://openalex.org/W2076195979', 'https://openalex.org/W2078819049', 'https://openalex.org/W2078850432', 'https://openalex.org/W2079882002', 'https://openalex.org/W2081158387', 'https://openalex.org/W2082726109', 'https://openalex.org/W2085946223', 'https://openalex.org/W2088254488', 'https://openalex.org/W2089003246', 'https://openalex.org/W2090450186', 'https://openalex.org/W2090859543', 'https://openalex.org/W2094494860', 'https://openalex.org/W2095805777', 'https://openalex.org/W2098000380', 'https://openalex.org/W2107640432', 'https://openalex.org/W2110590976', 'https://openalex.org/W2113010696', 'https://openalex.org/W2114769428', 'https://openalex.org/W2117515483', 'https://openalex.org/W2119098586', 'https://openalex.org/W2121422058', 'https://openalex.org/W2122708413', 'https://openalex.org/W2124178650', 'https://openalex.org/W2126384811', 'https://openalex.org/W2127314810', 'https://openalex.org/W2127453904', 'https://openalex.org/W2127825644', 'https://openalex.org/W2128190429', 'https://openalex.org/W2130904379', 'https://openalex.org/W2133761093', 'https://openalex.org/W2137573856', 'https://openalex.org/W2138661781', 'https://openalex.org/W2139206194', 'https://openalex.org/W2140906887', 'https://openalex.org/W2141621785', 'https://openalex.org/W2142179862', 'https://openalex.org/W2143092625', 'https://openalex.org/W2143102054', 'https://openalex.org/W2147033543', 'https://openalex.org/W2147546596', 'https://openalex.org/W2150880030', 'https://openalex.org/W2151843453', 'https://openalex.org/W2155675112', 'https://openalex.org/W2155738620', 'https://openalex.org/W2156354476', 'https://openalex.org/W2158939742', 'https://openalex.org/W2163881059', 'https://openalex.org/W2165275387', 'https://openalex.org/W2165774906', 'https://openalex.org/W2166680226', 'https://openalex.org/W2613251895', 'https://openalex.org/W4211217520'], 'related_works': ['https://openalex.org/W4295538067', 'https://openalex.org/W4249254036', 'https://openalex.org/W3170880456', 'https://openalex.org/W3000506725', 'https://openalex.org/W2776798182', 'https://openalex.org/W2775627464', 'https://openalex.org/W2771736620', 'https://openalex.org/W2767472409', 'https://openalex.org/W2008631375', 'https://openalex.org/W1538346717'], 'abstract_inverted_index': {'Inflammasomes': [0], 'are': [1], 'multi-protein': [2], 'signaling': [3, 95], 'complexes': [4, 80], 'that': [5], 'trigger': [6], 'the': [7, 13, 21, 39, 55, 59, 63, 69, 74, 84, 90, 117], 'activation': [8], 'of': [9, 15, 58, 77, 89, 116], 'inflammatory': [10, 100, 111], 'caspases': [11], 'and': [12, 27, 35, 96], 'maturation': [14], 'interleukin-1β.': [16], 'Among': [17], 'various': [18, 32], 'inflammasome': [19, 23, 41, 65, 79, 85, 94], 'complexes,': [20], 'NLRP3': [22, 40, 64, 78, 93, 118], 'is': [24, 66], 'best': [25], 'characterized': [26], 'has': [28], 'been': [29], 'linked': [30], 'with': [31, 114], 'human': [33], 'autoinflammatory': [34], 'autoimmune': [36], 'diseases.': [37], 'Thus,': [38], 'may': [42], 'be': [43], 'a': [44], 'promising': [45], 'target': [46], 'for': [47], 'anti-inflammatory': [48], 'therapies.': [49], 'In': [50], 'this': [51], 'review,': [52], 'we': [53], 'summarize': [54], 'current': [56], 'understanding': [57], 'mechanisms': [60, 91], 'by': [61], 'which': [62], 'activated': [67], 'in': [68], 'cytosol.': [70], 'We': [71], 'also': [72], 'describe': [73], 'binding': [75], 'partners': [76], 'activating': [81], 'or': [82], 'inhibiting': [83], 'assembly.': [86], 'Our': [87], 'knowledge': [88], 'regulating': [92], 'how': [97], 'these': [98], 'influence': [99], 'responses': [101], 'offers': [102], 'further': [103], 'insight': [104], 'into': [105], 'potential': [106], 'therapeutic': [107], 'strategies': [108], 'to': [109], 'treat': [110], 'diseases': [112], 'associated': [113], 'dysregulation': [115], 'inflammasome.': [119]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2118918019', 'counts_by_year': [{'year': 2024, 'cited_by_count': 113}, {'year': 2023, 'cited_by_count': 150}, {'year': 2022, 'cited_by_count': 153}, {'year': 2021, 'cited_by_count': 178}, {'year': 2020, 'cited_by_count': 159}, {'year': 2019, 'cited_by_count': 120}, {'year': 2018, 'cited_by_count': 95}, {'year': 2017, 'cited_by_count': 62}, {'year': 2016, 'cited_by_count': 27}], 'updated_date': '2024-09-15T02:08:27.984305', 'created_date': '2016-06-24'}