Publication Information

{'id': 'https://openalex.org/W2118705031', 'doi': 'https://doi.org/10.1194/jlr.m015776', 'title': 'Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study', 'display_name': 'Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study', 'publication_year': 2011, 'publication_date': '2011-08-06', 'ids': {'openalex': 'https://openalex.org/W2118705031', 'doi': 'https://doi.org/10.1194/jlr.m015776', 'mag': '2118705031', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21821825', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3173004'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1194/jlr.m015776', 'pdf_url': 'http://www.jlr.org/article/S0022227520408478/pdf', 'source': {'id': 'https://openalex.org/S11400418', 'display_name': 'Journal of Lipid Research', 'issn_l': '0022-2275', 'issn': ['0022-2275', '1539-7262'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jlr.org/article/S0022227520408478/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045297090', 'display_name': 'Amir Ravandi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Amir Ravandi', 'raw_affiliation_strings': ['Division of Cardiology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.'], 'affiliations': [{'raw_affiliation_string': 'Division of Cardiology, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090498118', 'display_name': 'S. 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'sections': [445], 'should': [447], 'have': [448, 685, 912, 1583], 'appeared': [449], 'first': [452], 'page': [453], 'each': [455, 1530], 'manuscript.': [456], 'Full-Text': [457], 'PDF': [458, 526, 626, 674, 807, 1073, 1268, 1418, 2542, 3033], 'Open': [459, 3521], 'Access': [460], 'Oxidized': [461, 480, 1728, 2206], 'low': [462, 788, 942, 1758, 4077], 'density': [463, 789, 943, 1759, 1764], '(OxLDL)': [465], 'plays': [466], 'a': [467, 536, 554, 903, 1514, 1842, 2096, 2384, 2419, 2757, 2796, 2945, 2989, 3021, 3062, 3072, 3298, 3524, 3571, 4012, 4114], 'major': [468, 583], 'role': [469, 511, 611], 'initiation': [471], 'progression': [473, 717, 1628, 1815, 2342], 'atherosclerosis': [475, 829, 1633, 2347], '(1Steinberg': [476], 'D.': [477, 1836, 2719, 2998], 'Witztum': [478, 508, 608, 648, 710, 733, 772, 835, 874, 974, 1006, 1292, 1442, 1670, 1722, 1808, 1837, 1895, 1927, 1980, 2016, 2147, 2184, 2269, 2624], 'J.L.': [479, 509, 609, 649, 711, 734, 773, 836, 875, 975, 1007, 1293, 1443, 1671, 1723, 1809, 1834, 1838, 1896, 1928, 1981, 2017, 2148, 2185, 2270, 2625], 'low-density': [481, 983, 1136, 1679, 1729, 1904, 2039, 2156, 2252], 'atherosclerosis.Arterioscler.': [484, 890], 'Thromb.': [485, 753, 855, 891, 1104, 1864, 2697], 'Vasc.': [486, 754, 856, 892, 1105, 2698], 'Biol.': [487, 755, 857, 893, 1106, 2699], '2010;': [488, 667, 1195, 1309, 1459, 2641, 2923], '30:': [489, 2743], '2311-2316Crossref': [490], 'PubMed': [491, 527, 627, 675, 724, 759, 808, 861, 897, 999, 1047, 1074, 1110, 1146, 1198, 1269, 1312, 1419, 1462, 1651, 1707, 1748, 1822, 1868, 1920, 1968, 1997, 2044, 2172, 2201, 2259, 2310, 2365, 2481, 2543, 2644, 2703, 2745, 2926, 3034, 3861], 'Scopus': [492, 528, 628, 676, 725, 760, 809, 862, 898, 1000, 1048, 1075, 1111, 1199, 1270, 1313, 1420, 1463, 1652, 1708, 1749, 1823, 1869, 1921, 1969, 1998, 2045, 2173, 2202, 2260, 2311, 2366, 2482, 2544, 2645, 2704, 2746, 2927, 3035, 3862], '(346)': [493, 2483], 'Google': [494, 530, 630, 678, 727, 762, 811, 864, 900, 958, 1002, 1050, 1077, 1113, 1147, 1201, 1272, 1315, 1422, 1465, 1654, 1710, 1751, 1825, 1871, 1923, 1971, 2000, 2047, 2175, 2204, 2262, 2313, 2368, 2484, 2546, 2647, 2706, 2748, 2929, 3037, 3864], 'Scholar,': [495, 631, 728, 763, 865, 959, 1003, 1051, 1078, 1114, 1273, 1423, 1655, 1711, 1826, 1924, 1972, 2001, 2176, 2314, 2648, 2707], '2Hartvigsen': [496], 'K.': [497, 597, 707, 1130, 1805], 'Chou': [498, 598], 'M.Y.': [499, 599], 'Hansen': [500, 600, 933], 'L.F.': [501, 601, 934], 'Shaw': [502, 602], 'P.X.': [503, 603], 'Tsimikas': [504, 604, 650, 937, 1672, 1726], 'S.': [505, 605, 651, 697, 701, 730, 765, 832, 938, 961, 1005, 1053, 1082, 1275, 1425, 1602, 1604, 1618, 1673, 1727, 1795, 1799, 1882, 1926, 2003, 2134, 2217, 2268, 2316, 2318, 2332, 2607, 2996], 'Binder': [506, 606], 'C.J.': [507, 607], 'The': [510, 610, 1149, 1545, 2760, 2774, 2831, 2860, 3936], 'innate': [513, 613], 'immunity': [514, 614], 'atherogenesis.J.': [516, 616], 'Res.': [518, 618, 799, 3025], '2009;': [519, 619, 2742], '50:': [520, 620, 2479], 'S388-S393Abstract': [521, 621], 'Full': [522, 524, 622, 624, 670, 672, 803, 805, 1069, 1071, 1264, 1266, 1414, 1416, 2538, 2540, 3029, 3031], 'Text': [523, 525, 623, 625, 671, 673, 804, 806, 1070, 1072, 1265, 1267, 1415, 1417, 2539, 2541, 3030, 3032], '(121)': [529, 629], 'Scholar).': [531, 679, 812, 901, 1148, 1202, 1466, 1752, 2048, 2205, 2749, 3038, 3865], 'OxLDL': [532, 567, 1986, 2190], 'does': [533], 'represent': [535], 'single': [537], 'entity': [538], 'because': [539], 'both': [540, 689, 1330, 3983], 'protein': [542, 1240, 1390, 2490, 2514], 'lipid': [545], 'components': [546, 3581], 'can': [547, 551, 568, 2883, 2893], 'be': [548], 'oxidized,': [549], 'which': [550, 1317, 2951, 3978, 3991], 'result': [552], 'heterogeneous': [555], 'group': [556], 'molecules': [558, 595], 'only': [562, 2875, 3755], 'pro-inflammatory': [563], 'also': [565, 2894], 'immunogenic.': [566], 'initiate': [569], 'cell-mediated': [570], 'humoral': [572, 1188], 'responses': [573, 2036], 'resulting': [574], 'activation': [576], 'macrophages': [578, 661], 'leading': [579], 'overexpression': [581], 'histocompatibility': [584], 'complex-II': [585], 'molecules,': [586], 'cytokine': [587], 'chemokine': [589], 'release,': [590], 'expression': [592], 'costimulatory': [594], '(2Hartvigsen': [596], '3Seimon': [632], 'T.A.': [633], 'Nadolski': [634], 'M.J.': [635, 3828], 'Liao': [636], 'X.': [637], 'Magallon': [638], 'J.': [639, 969, 973, 1064, 1289, 1439, 1606, 1713, 1890, 1894, 1983, 2142, 2146, 2187, 2320, 2574, 2621, 2717, 2741, 3004], 'Nguyen': [640], 'M.': [641, 1013, 1116, 1118, 1608, 1663, 1934, 2276, 2322], 'Feric': [642], 'N.T.': [643], 'Koschinsky': [644], 'M.L.': [645, 3822], 'Harkewicz': [646], 'R.': [647, 699, 705, 967, 1080, 1225, 1375, 1797, 1803, 1888, 1974, 2140, 2178, 2447, 2499, 2656], 'et': [652, 1238, 1294, 1388, 1444, 1621, 2236, 2335, 2452, 2512, 2626, 2669, 2901, 3835], 'al.Atherogenic': [653], 'lipids': [654], 'lipoproteins': [656], 'trigger': [657], 'CD36–TLR2-dependent': [658], 'apoptosis': [659], 'undergoing': [662], 'endoplasmic': [663], 'reticulum': [664], 'stress.Cell': [665], 'Metab.': [666], '12:': [668], '467-482Abstract': [669], '(343)': [677], 'Autoantibodies': [680, 1984, 2188], 'against': [682, 713, 879, 1092, 1134, 1811], 'modified': [683, 825, 1096, 1192, 1875, 2266], 'LDL': [684, 715, 739, 748, 750, 826, 841, 850, 852, 883, 885, 1097, 1787, 1813], 'been': [686], 'isolated': [687], 'from': [688, 816, 909, 1481, 1641, 1690, 2355, 2825], 'animal': [690, 817], 'human': [692, 910, 1154, 1877, 2079, 2100, 2127], 'plasma': [693, 979, 1022, 1900, 1943, 2060, 2152, 2285, 2389, 2727, 2839, 2852, 3622, 3778], '(4Salonen': [694, 1792], 'J.T.': [695, 1793], 'Yla-Herttuala': [696, 1794], 'Yamamoto': [698, 1796], 'Butler': [700, 1798], 'Korpela': [702, 1800], 'H.': [703, 1086, 1801, 2223, 2578, 2715], 'Salonen': [704, 1802], 'Nyyssonen': [706, 1804], 'Palinski': [708, 731, 833, 1806], 'W.': [709, 732, 834, 867, 1807, 1828, 2709], 'Autoantibody': [712, 1810], 'oxidised': [714, 1812], 'carotid': [719, 1630, 1817, 2344], 'atherosclerosis.Lancet.': [720, 1818], '1992;': [721, 1819], '339:': [722, 1820], '883-887Abstract': [723, 1821], '(1199)': [726, 1824], '5Tsimikas': [729], 'Circulating': [735, 837], 'correlate': [740, 827, 842], 'arterial': [742, 844], 'accumulation': [743, 845], 'depletion': [745, 847], 'receptor-deficient': [751, 853, 886], 'mice.Arterioscler.': [752, 854], '2001;': [756, 858], '21:': [757, 859], '95-100Crossref': [758, 860], '(134)': [761, 863], '6Tsimikas': [764], 'Brilakis': [766], 'E.S.': [767, 2434, 3826], 'Lennon': [768], 'R.J.': [769, 1231, 1381, 2505], 'Miller': [770, 870, 970, 1008, 1286, 1436, 1609, 1660, 1718, 1891, 1929, 2010, 2143, 2220, 2271, 2323, 2618], 'E.R.': [771, 1009, 1287, 1437, 1610, 1719, 1930, 2011, 2272, 2324, 2619], 'McConnell': [774], 'J.P.': [775], 'Kornman': [776], 'K.S.': [777], 'Berger': [778], 'P.B.': [779], 'Relationship': [780, 1674], 'cardiovascular': [796, 925, 952, 1062, 1354, 1636, 2350, 2732, 2915, 3107, 3304, 3848], 'events.J.': [797, 1305, 1455, 2637], '2007;': [800, 955, 2478], '48:': [801], '425-433Abstract': [802], '(196)': [810], 'There': [813, 3569, 3866, 4092], 'is': [814, 1156, 1318, 2417, 2871, 2952, 3979, 3992], 'evidence': [815], 'studies': [818, 911, 946, 1155, 1179], 'increasing': [820, 3687], 'burden': [830], '(5Tsimikas': [831], '7Palinski': [866], 'Tangirala': [868], 'R.K.': [869], 'E.': [871, 932, 971, 1661, 1892, 2144, 2221, 3010], 'Young': [872], 'S.G.': [873], 'Increased': [876], 'autoantibody': [877], 'titers': [878, 1857], 'epitopes': [880, 1852], 'mice': [887, 1840], 'increased': [889], '1995;': [894, 2594], '15:': [895], '1569-1576Crossref': [896], '(215)': [899, 2046], 'For': [902, 4005], 'variety': [904], 'reasons,': [906], 'results': [908, 1640, 2023, 2354, 3019], 'consistently': [914], 'shown': [915, 1585, 3093, 3481, 3529], 'or': [918, 927, 1594, 2066, 2081, 2109, 2129, 2243, 2770, 2934, 2968, 3120, 3339, 3488, 3536, 3591, 3598, 3627, 4147, 4150, 4153], 'immune': [919, 1028, 1189, 1949, 2291, 3454, 3461], '(8Gounopoulos': [929], 'P.': [930, 2231], 'Merki': [931], 'Choi': [935], 'S.H.': [936, 1657], 'Antibodies': [939, 1091], 'lipoprotein:': [944], 'potential': [948], 'clinical': [949, 2604], 'applications': [950, 1878], 'disease.Minerva': [953], 'Cardioangiol.': [954], '55:': [956], '821-837PubMed': [957], '9Tsimikas': [960], 'Bergmark': [962, 1615, 1883, 2135, 2329], 'C.': [963, 1126, 1616, 1884, 1979, 2136, 2183, 2330, 2570, 3002, 3824], 'Beyer': [964, 1885, 2137], 'R.W.': [965, 1886, 2138], 'Patel': [966, 1887, 2139], 'Pattison': [968, 1889, 2141], 'Juliano': [972, 1893, 2145], 'Temporal': [976, 1897, 2149], 'increases': [977, 1898, 2026, 2150], 'markers': [980, 1349, 1901, 2153], 'strongly': [985, 1906, 2158], 'reflect': [986, 1907, 2159], 'presence': [988, 1626, 1909, 2161, 2340], 'acute': [990, 1037, 1911, 1958, 2025, 2163, 2300], 'syndromes.J.': [992, 1913, 2165], 'Am.': [993, 1306, 1456, 1645, 1701, 1742, 1914, 2166, 2359, 2475, 2638, 3855], 'Coll.': [994, 1307, 1457, 1646, 1702, 1743, 1915, 2167, 2360, 2476, 2639, 3856], 'Cardiol.': [995, 1065, 1308, 1458, 1647, 1703, 1744, 1916, 2168, 2361, 2477, 2640, 3857], '2003;': [996, 1917, 2169, 3026], '41:': [997, 1918, 2170, 2595], '360-370Crossref': [998, 1919, 2171], '(315)': [1001, 1922, 2174], '10Tsimikas': [1004, 1925], 'Sasiela': [1010, 1931, 2273], 'W.J.': [1011, 1932, 2274], 'Szarek': [1012, 1933, 2275], 'Olsson': [1014, 1935, 2277, 3833], 'A.G.': [1015, 1936, 2278, 3834], 'Schwartz': [1016, 1937, 2279], 'G.G.': [1017, 1938, 2280], 'High-dose': [1018, 1939, 2281], 'atorvastatin': [1019, 1940, 2282], 'reduces': [1020, 1941, 2283], 'total': [1021, 1756, 1942, 2284, 3798], 'present': [1030, 1951, 2293], 'apolipoprotein': [1032, 1953, 2295, 3515, 3563, 3844], 'B-100': [1033, 1954, 2296], 'patients': [1035, 1956, 2298, 2735, 3014], 'syndromes': [1039, 1960, 2302], 'MIRACL': [1042, 1963, 2305], 'trial.Circulation.': [1043, 1964, 2306], '2004;': [1044, 1965, 2041, 2307], '110:': [1045, 1966, 2308], '1406-1412Crossref': [1046, 1967, 2309], '(188)': [1049, 1970, 2312], '11Tsimikas': [1052], 'Oxidative': [1054], 'biomarkers': [1055, 1588, 1676, 3984], 'diagnosis': [1058], 'prognosis': [1060], 'disease.Am.': [1063], '2006;': [1066, 1261, 1411, 1648, 1745, 2362, 2535], '98:': [1067], '9P-17PAbstract': [1068], '(87)': [1076, 1709], '12Wu': [1079], 'Nityanand': [1081], 'Berglund': [1083], 'L.': [1084, 1122, 3008], 'Lithell': [1085], 'Holm': [1087], 'G.': [1088, 1124, 1183, 2227, 2906], 'Lefvert': [1089], 'A.K.': [1090], 'cardiolipin': [1093], 'oxidatively': [1095], '50-year-old': [1099], 'men': [1100, 1252, 1402, 1470, 2526, 2689, 3199], 'predict': [1101, 1624, 2338], 'myocardial': [1102, 1139], 'infarction.Arterioscler.': [1103], '1997;': [1107], '17:': [1108], '3159-3163Crossref': [1109], '(204)': [1112], '13Puurunen': [1115], 'Manttari': [1117], 'Manninen': [1119], 'V.': [1120], 'Tenkanen': [1121], 'Alfthan': [1123], 'Ehnholm': [1125], 'Vaarala': [1127], 'O.': [1128, 3832], 'Aho': [1129], 'Palosuo': [1131], 'T.': [1132], 'Antibody': [1133], 'predicting': [1138], 'infarction.Arch.': [1140], 'Intern.': [1141], 'Med.': [1142], '1994;': [1143, 1865], '154:': [1144], '2605-2609Crossref': [1145], 'heterogeneity': [1150], 'findings': [1152], 'likely': [1157], 'due': [1158], 'part': [1160, 1213], 'differences': [1162, 3335], 'populations': [1165, 2605], 'studied,': [1166], 'methodologies': [1168], 'measuring': [1169], 'AA,': [1170], 'lack': [1173], 'statistical': [1175, 3251, 3955], 'power': [1176], 'small': [1178], '(14Lopes-Virella': [1180], 'M.F.': [1181], 'Virella': [1182], 'Clinical': [1184, 1577], 'significance': [1185, 3846], 'response': [1190], 'LDL.Clin.': [1193], 'Immunol.': [1194, 2591], '134:': [1196], '55-65Crossref': [1197], '(56)': [1200, 2747], 'this': [1204], 'study': [1205, 1217, 1259, 1359, 1409, 1553, 2533, 3354], 'constituting': [1206], 'as': [1212, 1506, 1521, 1789, 1879, 2131, 2213, 2404, 2550, 2564, 2842, 2856, 2918, 2992, 3080, 3133, 3482, 3530, 3763], '(15Boekholdt': [1218, 1368, 2492], 'S.M.': [1219, 1369, 2493, 2650, 3820], 'Hack': [1220, 1370, 2494, 2579, 2667], 'C.E.': [1221, 1371, 2495, 2580, 2668], 'Sandhu': [1222, 1284, 1372, 1434, 2496, 2616, 2661], 'M.S.': [1223, 1285, 1373, 1435, 2497, 2617, 2662], 'Luben': [1224, 1374, 2446, 2498, 2655], 'Bingham': [1226, 1376, 2500, 2657], 'S.A.': [1227, 1377, 2501, 2658], 'Wareham': [1228, 1282, 1378, 1432, 2444, 2502, 2614, 2653, 3829], 'N.J.': [1229, 1283, 1379, 1433, 2445, 2503, 2615, 2654, 3830], 'Peters': [1230, 1380, 2504], 'Jukema': [1232, 1382, 2506, 2663], 'J.W.': [1233, 1383, 2507, 2572, 2664], 'Day': [1234, 1384, 2508, 2659], 'N.E.': [1235, 1385, 2509, 2660], 'Kastelein': [1236, 1280, 1386, 1430, 1724, 2448, 2510, 2612, 2665], 'J.J.': [1237, 1281, 1387, 1431, 1725, 2449, 2511, 2613, 2666], 'al.C-reactive': [1239, 1389, 2513], 'incidence': [1246, 1396, 2520], 'mortality': [1248, 1398, 2522], 'apparently': [1250, 1400, 2467, 2524, 2687], 'women:': [1254, 1404, 2528, 2691], 'prospective': [1257, 1407, 1639, 2353, 2531], 'population': [1258, 1408, 2532], '1993–2003.Atherosclerosis.': [1260, 1410, 2534], '187:': [1262, 1412, 2536], '415-422Abstract': [1263, 1413, 2537], '(155)': [1271, 1421, 1653, 2367, 2545], '16Tsimikas': [1274, 1424], 'Mallat': [1276, 1426, 2608, 2712, 2900], 'Z.': [1277, 1427, 2609, 2713, 2904], 'Talmud': [1278, 1428, 2610], 'P.J.': [1279, 1429, 2611], 'Benessiano': [1288, 1438, 2620, 2716], 'Tedgui': [1290, 1440, 2622, 2907], 'A.': [1291, 1441, 1659, 1717, 2013, 2623, 2908], 'al.Oxidation-specific': [1295, 1445, 2627], 'biomarkers,': [1296, 1446, 2628, 3946], 'lipoprotein(a),': [1297, 1447, 2629], 'fatal': [1301, 1451, 2633], 'nonfatal': [1303, 1453, 2635], '56:': [1310, 1460, 2642], '946-955Crossref': [1311, 1461, 2643], '(128)': [1314, 1464, 2646], 'Scholar),': [1316, 2485], 'adequately': [1319], 'powered': [1320], 'address': [1322], 'hypothesis,': [1324], 'we': [1325, 3110], 'assessed': [1344], 'impact': [1346], 'other': [1348, 2880, 3945, 4063, 4088, 4158], 'inflammation': [1351], 'prediction': [1353], 'outcomes.': [1355], 'A': [1356, 2913, 4067], 'nested': [1357], 'case-control': [1358], 'designed': [1361], 'among': [1362], 'participants': [1363, 1556], 'Briefly,': [1467], '25,663': [1468], 'women': [1472, 3201], 'aged': [1473], 'between': [1474, 1491, 1675, 2721, 2778, 3043, 3051, 3248, 3344, 3576, 3871, 3938, 4016, 4040, 4100, 4117], '45': [1475], '79': [1477], 'years': [1478], 'recruited': [1480], 'age-sex': [1482], 'registers': [1483], 'general': [1485], 'practices': [1486], 'Norfolk': [1488], 'enrolled': [1490], '1993': [1492], '1997': [1494], 'followed': [1496], 'an': [1498, 2561, 3134, 3997], 'average': [1499], '6': [1501], 'years.': [1502], 'Participants': [1503], 'identified': [1505], 'having': [1507], 'during': [1509], 'follow-up': [1510], 'if': [1511], 'they': [1512], 'had': [1513, 3297], 'hospital': [1515], 'admission': [1516], 'and/or': [1517], 'died': [1518], 'underlying': [1523], 'cause.': [1524], 'Two': [1525], 'matched': [1528], 'case': [1531], 'by': [1532, 2088, 2795, 2800, 3213, 3745, 3952, 3994], 'sex,': [1533, 3157], 'age': [1534, 3788], '(within': [1535, 1542], '5': [1536], 'years)': [1537], 'time': [1539, 3161], 'enrollment': [1541, 3160], '3': [1543, 3214, 3216, 3958, 3960], 'months).': [1544], 'Norwich': [1546], 'Health': [1547], 'Authority': [1548], 'Ethics': [1549], 'Committee': [1550], 'approved': [1551], 'all': [1555, 3302], 'provided': [1557, 3244], 'written': [1558], 'informed': [1559], 'consent.': [1560], 'Plasma': [1561, 1753, 2102, 2553, 2790, 3011], 'samples': [1562, 2846], 'drawn': [1564], 'at': [1565, 1573, 1575, 2965], 'baseline': [1566], '(1993–1997)': [1567], 'EDTA': [1569], 'stored': [1572], '−80°C': [1574], 'School,': [1578], 'University': [1579], 'Cambridge.': [1581], 'previously': [1584, 2214, 2551, 2994], 'these': [1587], 'stable': [1590], 'prolonged': [1592], 'freezing': [1593], 'transport': [1595], 'processing': [1597], 'sites': [1598], 'ice': [1600], '(17Tsimikas': [1601], 'Kiechl': [1603, 2317], 'Willeit': [1605, 2319], 'Mayr': [1607, 2321], 'Kronenberg': [1611, 2325], 'F.': [1612, 1620, 1665, 2326, 2334, 3006], 'Xu': [1613, 2327], 'Q.': [1614, 2328], 'Weger': [1617, 2331], 'Oberhollenzer': [1619, 2333], 'al.Oxidized': [1622, 2336], 'femoral': [1632, 2346], 'symptomatic': [1635, 2349], 'disease:': [1637, 2351, 2916, 3018], 'five-year': [1638, 2352], 'Bruneck': [1643, 2357], 'study.J.': [1644, 1700, 2358], '47:': [1649, 1746, 2363], '2219-2228Crossref': [1650, 2364], '18Choi': [1656], 'Chae': [1658], 'Messig': [1662], 'Ntanios': [1664], 'DeMaria': [1666], 'A.N.': [1667], 'Nissen': [1668], 'S.E.': [1669], 'lipoprotein,': [1680], 'statin': [1681], 'therapy,': [1682], 'quantitative': [1683], 'angiography,': [1685], 'atheroma:': [1687], 'volume': [1688], 'observations': [1689], 'REVERSAL': [1692], '(Reversal': [1693], 'Atherosclerosis': [1695], 'Aggressive': [1697], 'Lowering)': [1699], '2008;': [1704, 3858], '52:': [1705], '24-32Crossref': [1706], '19Rodenburg': [1712], 'Vissers': [1714], 'M.N.': [1715], 'Wiegman': [1716], 'Ridker': [1720], 'P.M.': [1721], 'children': [1732], 'familial': [1734], 'hypercholesterolemia': [1735], 'unaffected': [1737], 'siblings:': [1738], 'effect': [1739], 'pravastatin.J.': [1741], '1803-1810Crossref': [1747], '(85)': [1750], 'cholesterol,': [1757, 3401, 3407, 3413, 3799, 3838], 'cholesterol': [1761, 1766], '(LDL-C),': [1762], '(HDL-C),': [1767], 'triglycerides': [1769], 'commercial': [1773], 'kits.': [1774], 'Chemiluminescence': [1775], 'ELISAs': [1776], 'used': [1778, 2841, 3057, 3066, 3079], 'measure': [1780, 2410, 2422], 'malondialdehyde-modified': [1786], '(MDA-LDL)': [1788], 'described': [1791, 1880, 2215, 2566], '20Palinski': [1827], 'Ord': [1829], 'V.A.': [1830], 'Plump': [1831], 'A.S.': [1832], 'Breslow': [1833], 'Steinberg': [1835], 'ApoE-deficient': [1839], 'model': [1843, 3064], 'oxidation': [1846], 'atherogenesis.': [1848], 'Demonstration': [1849], 'oxidation-specific': [1851], 'lesions': [1854], 'malondialdehyde-lysine': [1861], 'serum.Arterioscler.': [1863], '14:': [1866], '605-616Crossref': [1867], '(473)': [1870], 'Scholar)': [1872, 2263, 2369, 2547, 2597], 'subsequently': [1874, 2265, 2599], '(9Tsimikas': [1881, 2133], '21Wu': [1973, 2177], 'de': [1975, 2179], 'Faire': [1976, 2180], 'U.': [1977, 2181], 'Lemne': [1978, 2182], 'Frostegard': [1982, 2186], 'decreased': [1988, 2192], 'individuals': [1990, 2194], 'borderline': [1992, 2196], 'hypertension.Hypertension.': [1993, 2197], '1999;': [1994, 2198, 2256], '33:': [1995, 2199], '53-59Crossref': [1996, 2200], '(108)': [1999, 2203, 3036], '22Tsimikas': [2002], 'Lau': [2004], 'H.K.': [2005], 'Han': [2006], 'K.R.': [2007], 'Shortal': [2008], 'B.': [2009], 'Segev': [2012], 'Curtiss': [2014, 2234], 'L.K.': [2015, 2235], 'Strauss': [2018], 'B.H.': [2019], 'Percutaneous': [2020], 'intervention': [2022], 'lipoprotein(a):': [2031], 'short-term': [2032], 'long-term': [2034], 'immunologic': [2035], 'lipoprotein.Circulation.': [2040], '109:': [2042], '3164-3170Crossref': [2043], 'brief,': [2050, 2374, 2751], '(5': [2052], 'µg/ml)': [2053], 'coated': [2055], 'microtiter': [2057, 2379], 'well': [2058, 2380], 'plates,': [2059], '(1:200': [2061], 'dilution)': [2062, 2104], 'added,': [2063], 'binding': [2069, 2112], 'detected': [2072, 2087, 2120, 2395], 'alkaline': [2074, 2122], 'phosphatase': [2075, 2123], 'labeled': [2076, 2124, 3989], 'goat': [2077, 2125], 'anti': [2078, 2126], '(Sigma).': [2083], 'ApoB-100': [2084], 'plating': [2089], 'murine': [2090, 2398], 'monoclonal': [2091, 2399], 'antibody': [2092, 2400], 'MB47': [2093, 2375], 'bind': [2095, 2383], 'saturating': [2097, 2385], 'amount': [2098, 2386], 'apoB.': [2101], '(1:50': [2103, 2391], 'added': [2106, 2377, 2390], 'captured': [2115], 'apoB': [2116], '(i.e.,': [2117, 3985], 'apoB-IC)': [2118], 'above': [2132, 2957], '(OxPL/apoB)': [2210], '(23Hörkko': [2216], 'Bird': [2218], 'D.A.': [2219], 'Itabe': [2222], 'Leitinger': [2224], 'N.': [2225], 'Subbanagounder': [2226], 'Berliner': [2228], 'J.A.': [2229, 2441], 'Friedman': [2230], 'Dennis': [2232], 'E.A.': [2233], 'al.Monoclonal': [2237], 'specific': [2239, 2873], 'phospholipid-protein': [2245], 'adducts': [2246], 'inhibit': [2247], 'macrophage': [2248], 'uptake': [2249], 'lipoproteins.J.': [2253], 'Clin.': [2254], 'Invest.': [2255], '103:': [2257], '117-128Crossref': [2258], '(474)': [2261], '(10Tsimikas': [2267], '17Tsimikas': [2315], 'using': [2370, 2801, 2821, 3146, 3256, 3280], 'chemiluminescent': [2371], 'ELISA.': [2372, 2759], 'plates': [2381], 'apoB-100,': [2388], 'dilution),': [2392], 'OxPL': [2394, 2415], 'biotinylated': [2397], 'E06': [2401, 2412], 'read': [2403], 'relative': [2405, 3138, 3518, 3566], 'light': [2406, 3519, 3567], 'units': [2407], '(RLU).': [2408], 'represents': [2411], 'immunoreactivity': [2413], 'direct': [2420], 'chemical': [2421], 'OxPL.': [2424], 'Lipoprotein': [2425], '[Lp(a)]': [2427], '(22),': [2428], 'myeloperoxidase': [2429, 2454, 3241, 3317], '(24Meuwese': [2431], 'M.C.': [2432], 'Stroes': [2433, 3825], 'Hazen': [2435], 'S.L.': [2436], 'van': [2437, 2575], 'Miert': [2438], 'J.N.': [2439], 'Kuivenhoven': [2440], 'Schaub': [2442], 'R.G.': [2443], 'Khaw': [2450], 'K.T.': [2451], 'al.Serum': [2453, 2670], 'future': [2460, 2682], 'individuals:': [2469], 'Prospective': [2472, 2694], 'Population': [2473, 2695], 'Study.J.': [2474], '159-165Crossref': [2480], '(hsCRP)': [2491], 'described.': [2552], 'performed': [2559, 3180, 3197, 3212, 3279], 'in-house': [2562], 'assay': [2563, 2799, 2949, 2991], 'originally': [2565], '(25Wolbink': [2567], 'G.J.': [2568], 'Schalkwijk': [2569], 'Baars': [2571], 'Wagstaff': [2573], 'den': [2576], 'Bosch': [2577], 'Therapy': [2581], 'interleukin-2': [2583], 'induces': [2584], 'systemic': [2586], 'release': [2587], 'phospholipase-A2.': [2589], 'Cancer': [2590], 'Immunother.C': [2592], 'II.': [2593], '287-292Google': [2596], 'reported': [2600, 2993, 3762], 'large': [2603], '(16Tsimikas': [2606], '26Boekholdt': [2649], 'Keller': [2651], 'T.T.': [2652], 'II': [2674, 2723], 'Study.Arterioscler.': [2696], '2005;': [2700], '25:': [2701], '839-846Crossref': [2702], '(99)': [2705], '27Koenig': [2708], 'Vossen': [2710], 'C.Y.': [2711], 'Brenner': [2714], 'Rothenbacher': [2718], 'Association': [2720], 'concentrations': [2728, 2970], 'activity': [2730, 2792, 2853, 2863, 2974, 2982], 'heart': [2738], 'disease.Eur.': [2739], 'Heart': [2740], '2742-2748Crossref': [2744], 'sandwich-type': [2758], 'measurement': [2761], 'no': [2763, 2978, 3333, 3868, 4094], 'cross-reactivity': [2764], 'I,': [2767], 'IV,': [2768], 'V,': [2769], 'X': [2772], 'sPLA2.': [2773], 'mean': [2775, 3112], 'intra-assay': [2776], 'variation': [2777], 'duplicates': [2779], '9.2%': [2781], 'lower': [2784, 3685, 3728], 'detection': [2785], 'limit': [2786], '0.4': [2788], 'ng/ml.': [2789], 'selective': [2797], 'fluorometric': [2798], 'fluorescent': [2802, 2817], 'substrate': [2803, 2818, 2834, 2886], '1-hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3': [2804], 'phosphomethanol,': [2805], 'sodium': [2806], 'salt': [2807], '(Interchim,': [2808], 'Montluçon,': [2809], 'France).': [2810], 'One': [2811], 'hundred': [2812], 'percent': [2813], 'hydrolysis': [2814, 2832], '0.1': [2822], 'U': [2823], 'bee': [2826], 'venom': [2827], '(Sigma': [2828], 'Chemical': [2829], 'Co).': [2830], 'absence': [2837], 'negative': [2843], 'control.': [2844], 'All': [2845], 'tested': [2848], 'duplicate': [2850], 'expressed': [2855], 'nmol/min': [2857, 2866, 3435], 'per': [2858, 2867, 3116, 3436], 'ml.': [2859, 2868], 'minimum': [2861], 'detectable': [2862, 2979], '0.10': [2865], 'method': [2870, 3259], 'calcium-sensitive': [2881], 'phospholipases': [2882, 2912], 'hydrolyze': [2884, 2895], 'used.': [2887], 'contrast': [2889], 'Lp-PLA2,': [2891, 3507, 3555], 'unmodified': [2896], '[reviewed': [2898], 'al.': [2902], '(28Mallat': [2903], 'Lambeau': [2905], 'Lipoprotein-associated': [2909], 'secreted': [2911], 'roles': [2917], 'biological': [2919], 'effectors': [2920], 'biomarkers.Circulation.': [2922], '122:': [2924], '2183-2200Crossref': [2925], '(136)': [2928], 'Scholar)].': [2930], 'Addition': [2931], 'purified': [2933], 'recombinant': [2935], 'Lp-PLA2': [2936, 2960, 2981, 3238, 3313], '[concentrations': [2937], 'up': [2938], '26': [2940], 'µg/ml': [2941], '(6': [2942], 'µg': [2943], '230': [2946], 'µL': [2947], 'final': [2948], 'volume),': [2950], 'two': [2953], 'orders': [2954], 'magnitude': [2956], 'median': [2959, 3489, 3537], 'physiological': [2961, 2967], '(200': [2963], 'ng/ml)]': [2964], 'pathological': [2969], 'our': [2972], 'assays': [2975], 'resulted': [2976], 'signal.': [2980], 'determined': [2984], 'use': [2987], 'radiometric': [2990], '(29Blankenberg': [2995], 'Stengel': [2997], 'Rupprecht': [2999], 'H.J.': [3000], 'Bickel': [3001], 'Meyer': [3003], 'Cambien': [3005], 'Tiret': [3007], 'Ninio': [3009], 'PAF-acetylhydrolase': [3012], 'cross-sectional': [3022], 'analysis.J.': [3023], '44:': [3027], '1381-1386Abstract': [3028], 'Baseline': [3039], 'characteristics': [3040, 3351], 'taking': [3047], 'into': [3048, 3152], 'account': [3049, 3153, 3272], 'matching': [3050, 3155], 'groups.': [3052], 'Conditional': [3053], 'logistic': [3054, 3148], 'categorical': [3059], 'variables': [3060, 3082, 3756], 'mixed-effect': [3063], 'continuous': [3068, 3081], 'variables.': [3069], 'Variables': [3070], 'skewed': [3073], 'distribution': [3074, 4131], 'log-transformed': [3076], 'before': [3077], 'being': [3078], 'untransformed': [3086], 'medians': [3087], 'corresponding': [3089, 3128], 'interquartile': [3090], 'ranges': [3091], 'tables.': [3095], 'To': [3096], 'determine': [3097], 'relationships': [3098, 3937], 'factors,': [3109, 3306], 'calculated': [3111, 3145], 'factor': [3114], 'tertile': [3117, 4127, 4139], 'AA.': [3121], 'addition,': [3123, 3205], 'odds': [3124, 3968], 'ratios': [3125, 3969, 4163], '(OR)': [3126], '95%': [3129], 'confidence': [3130, 3491, 3494, 3539, 3542], 'intervals': [3131], '(CI)': [3132], 'estimate': [3135], 'incident': [3141], 'conditional': [3147], 'regression.': [3149], 'Analyses': [3150, 3195], 'took': [3151], 'diabetes': [3165], 'mellitus,': [3166], 'smoking': [3167], '(never,': [3168], 'previous,': [3169], 'current),': [3170], 'LDL-C,': [3174, 3800], 'HDL-C.': [3176, 3803], 'Similar': [3177], '(FRS)': [3188], 'instead': [3189], 'separate': [3192, 3954], 'factors.': [3194], 'separately': [3202], 'sexes': [3207], 'pooled.': [3208], 'Additional': [3209], '×': [3215, 3959], 'according': [3218, 4169], 'OxPL/apoB,': [3231, 3307, 3511, 3559], 'Lp(a),': [3232, 3308, 3496, 3544], 'CRP,': [3233], 'mass.': [3242], 'Tertiles': [3243, 3730], 'best': [3246], 'balance': [3247], 'discrimination': [3249], 'power.': [3252], 'Correlations': [3253], 'computed': [3255], "Spearman's": [3257], 'rank-order': [3258], 'avoid': [3261], 'distributional': [3262], 'assumptions': [3263], 'P': [3265, 3287, 3758], '<': [3266, 3288, 3608, 3612, 3759], '0.001': [3267, 3760], 'considered': [3269, 3291], 'significant': [3270, 3334, 3573, 3869, 4095], 'multiple': [3274], 'comparisons.': [3275], 'Statistical': [3276], 'SPSS': [3281], 'software': [3282], '(version': [3283], '12.0.1,': [3284], 'Chicago,': [3285], 'IL).': [3286], '0.05': [3289], 'significant.': [3292, 3764], 'Compared': [3293], 'controls,': [3295], 'occurrence': [3300], 'traditional': [3303], 'hsCRP,': [3315, 3498, 3546], 'than': [3318, 3326], 'controls.': [3319], '0.02)': [3329, 4081], 'there': [3331, 4010, 4112], '(Table': [3348, 4065, 4090, 4109, 4160], '1).TABLE': [3349], '1Baseline': [3350], 'populationControlsCasespN1723748Age,': [3355], 'years65.4': [3356], '±': [3357, 3359, 3368, 3370, 3373, 3375, 3380, 3382, 3387, 3389, 3403, 3405, 3409, 3411, 3415, 3417, 3430, 3432, 3438, 3440, 3444, 3446, 3457, 3459, 3464, 3466, 3470, 3472, 3476, 3478, 3637, 3641, 3646, 3655, 3659, 3664, 3694, 3698, 3703, 3712, 3716, 3721], '7.865.4': [3358], '7.8matchedMale': [3360], '%': [3361, 3484, 3532], '(number)61.6': [3362], '(1061)62.8': [3363], '(470)matchedBody': [3364], 'index,': [3366], 'kg/m26.2': [3367], '3.527.3': [3369], '3.8<0.001Waist,': [3371], 'cm91': [3372], '1194': [3374], '12<0.001Systolic': [3376], 'mmHg139': [3379], '18143': [3381], '19<0.001Diastolic': [3383], 'mmHg83': [3386], '1186': [3388], '12<0.001Smoking': [3390], 'historyCurrent': [3391], 'smoker8.6': [3392], '(148)15.5': [3393], '(116)Former': [3394], 'smoker50.8': [3395], '(876)51.5': [3396], '(385)Never': [3397], 'smoked40.6': [3398], '(699)33.0': [3399], '(247)Total': [3400], 'mmol/l6.3': [3402], '1.16.5': [3404], '1.2<0.001LDL': [3406], 'mmol/l4.1': [3408], '1.04.3': [3410], '1.1<0.001HDL': [3412], 'mmol/l1.4': [3414], '0.41.3': [3416], '0.4<0.001Triglycerides,': [3418], 'mmol/l1.6': [3419], '(1.2–2.2)1.9': [3420], '(1.4–2.6)<0.001OxPL/apoB,': [3421], 'RLU1673': [3422], '(1144–2676)1902': [3423], '(1243–3247)<0.001Lp(a),': [3424], 'mg/dl8.4': [3425], '(6.5–13.8)9.7': [3426], '(7.0–25.6)<0.001sPLA2': [3427], 'mass,': [3428], 'ng/ml10.6': [3429], '8.412.5': [3431], '10.7<0.001sPLA2': [3433], 'ml4.5': [3437], '1.24.8': [3439], '1.5<0.001Lp-PLA2': [3441], 'nmol/min/ml50.6': [3443], '15.753.0': [3445], '16.50.001hsCRP,': [3447], 'mg/dl1.5': [3448], '(0.7–3.1)2.2': [3449], '(1.0–5.0)<0.001Myeloperoxidase,': [3450], 'pmol/L520': [3451], '(338–837)553': [3452], '(353–875)0.007IgG': [3453], 'complexes,': [3455, 3462], 'RLU2787': [3456], '12492924': [3458], '14990.02IgM': [3460], 'RLU1391': [3463], '12811333': [3465], '10720.3IgG': [3467], 'MDA-LDL,': [3468, 3474], 'RLU4855': [3469], '45475091': [3471], '57300.3IgM': [3473], 'RLU12888': [3475], '895012845': [3477], '93100.9Data': [3479], 'n,': [3483, 3531], '(n),': [3485, 3533], 'mean±': [3486, 3534], 'SD,': [3487, 3535], '(95%': [3490, 3538, 3878, 4164], 'interval).': [3492, 3540], 'CI,': [3493, 3541], 'interval;': [3495, 3543], 'lipoprotein(a);': [3497, 3545], 'protein;': [3502, 3550], 'sPLA2,': [3503, 3551], 'A2;': [3506, 3510, 3554, 3558], 'B-100;': [3516, 3564], 'RLU,': [3517, 3565], 'unit.': [3520, 3568], 'table': [3522], 'new': [3525], 'tab': [3526], 'Data': [3527], 'statistically': [3572], 'inverse': [3574, 4014, 4069], 'individual': [3580, 3971], '[waist': [3586], 'circumference': [3587], '≥': [3588, 3595, 3602, 3618, 3624], '102': [3589], 'cm': [3590, 3597], '40': [3592, 3609], 'inches': [3593], '(male),': [3594, 3611], '88': [3596], '36': [3599], 'inches(female),': [3600], 'TG': [3601], '1.7': [3603], 'mmol/L': [3604, 3626], '(150': [3605], 'mg/dl),': [3606], 'HDL-C': [3607, 3776], 'mg/dl': [3610, 3614], '50': [3613], '(female),': [3615], 'pressure': [3617], '130/85': [3619], 'mmHg,': [3620], 'fasting': [3621], 'glucose': [3623], '6.1': [3625], '110': [3628], 'mg/dl)]': [3629], '(T1:': [3635, 3653, 3692, 3710], '2.56': [3636], '1.02,': [3638], 'T2:': [3639, 3657, 3696, 3714, 3882, 3895, 3908, 3922], '2.48': [3640], '1.01,': [3642], 'T3:': [3644, 3662, 3701, 3719, 3885, 3898, 3911, 3925], '2.30': [3645], '1.08,': [3647], 'P=': [3648, 3666, 3705, 3723], '0.004)': [3649], '2.54': [3654], '1.04,': [3656], '2.49': [3658], '1.03,': [3660], '2.32': [3663], '1.06,': [3665], '0.02),': [3667], 'whereas': [3668], 'significantly': [3677], 'associated.': [3678], 'Similarly,': [3679], 'FRS': [3680], '10': [3681], 'year': [3682], 'estimates': [3683], '21.4%': [3693], '11.8,': [3695], '19.5%': [3697], '11.7,': [3699], '18.0%': [3702], '10.8,': [3704], '0.001)': [3706], '21.2%': [3711], '12.2,': [3713], '19.4%': [3715], '11.0,': [3717, 3722], '18.3%': [3720], '0.005)': [3724], 'calculated.': [3729], 'FRS.': [3741], 'Covariates': [3742], 'analyzed': [3744], 'positively': [3768], 'fibrinogen': [3771], 'vitamin': [3779], 'C': [3780], 'levels.': [3781, 3791], 'triglyceride': [3790], 'VLDL-C,': [3801], 'lipase': [3811], 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