Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2117041194', 'doi': 'https://doi.org/10.1242/jcs.115.8.1663', 'title': 'Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo', 'display_name': 'Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo', 'publication_year': 2002, 'publication_date': '2002-04-15', 'ids': {'openalex': 'https://openalex.org/W2117041194', 'doi': 'https://doi.org/10.1242/jcs.115.8.1663', 'mag': '2117041194', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11950885'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/jcs.115.8.1663', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055596979', 'display_name': 'Manuel Rojo', 'orcid': 'https://orcid.org/0000-0002-9680-9263'}, 'institutions': [{'id': 'https://openalex.org/I4210113666', 'display_name': 'Institut de Myologie', 'ror': 'https://ror.org/0270xt841', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I39804081', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210100892', 'https://openalex.org/I4210113666']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Manuel Rojo', 'raw_affiliation_strings': ["INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France"], 'affiliations': [{'raw_affiliation_string': "INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France", 'institution_ids': ['https://openalex.org/I4210113666', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058638576', 'display_name': 'Frédéric Legros', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210113666', 'display_name': 'Institut de Myologie', 'ror': 'https://ror.org/0270xt841', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I39804081', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210100892', 'https://openalex.org/I4210113666']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Frédéric Legros', 'raw_affiliation_strings': ["INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France"], 'affiliations': [{'raw_affiliation_string': "INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France", 'institution_ids': ['https://openalex.org/I4210113666', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027165489', 'display_name': 'Danielle Château', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092322', 'display_name': 'Centre de Recherche des Cordeliers', 'ror': 'https://ror.org/00dmms154', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I204730241', 'https://openalex.org/I39804081', 'https://openalex.org/I4210092322']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Danielle Chateau', 'raw_affiliation_strings': ['Present address: INSERM U 505, Centre de Recherches Biomédicales des Cordeliers, 75006 Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Present address: INSERM U 505, Centre de Recherches Biomédicales des Cordeliers, 75006 Paris, France', 'institution_ids': ['https://openalex.org/I4210092322', 'https://openalex.org/I154526488']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058903432', 'display_name': 'Anne Lombès', 'orcid': 'https://orcid.org/0000-0002-9064-0399'}, 'institutions': [{'id': 'https://openalex.org/I4210113666', 'display_name': 'Institut de Myologie', 'ror': 'https://ror.org/0270xt841', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I39804081', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210100892', 'https://openalex.org/I4210113666']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Anne Lombès', 'raw_affiliation_strings': ["INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France"], 'affiliations': [{'raw_affiliation_string': "INSERM U 523 — Institut de Myologie, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevard de l'Hôpital, 75651 Paris Cedex 13, France", 'institution_ids': ['https://openalex.org/I4210113666', 'https://openalex.org/I154526488']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.438, 'has_fulltext': False, 'cited_by_count': 529, 'citation_normalized_percentile': {'value': 0.999975, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '115', 'issue': '8', 'first_page': '1663', 'last_page': '1674'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12763', 'display_name': 'ATP Synthase and ATPases Research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolism and Genetic Disorders', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/mfn2', 'display_name': 'MFN2', 'score': 0.92038924}, {'id': 'https://openalex.org/keywords/mitochondrial-carrier', 'display_name': 'Mitochondrial carrier', 'score': 0.57133454}, {'id': 'https://openalex.org/keywords/coiled-coil', 'display_name': 'Coiled coil', 'score': 0.41821188}], 'concepts': [{'id': 'https://openalex.org/C2777092462', 'wikidata': 'https://www.wikidata.org/wiki/Q15334407', 'display_name': 'MFN2', 'level': 5, 'score': 0.92038924}, {'id': 'https://openalex.org/C163950672', 'wikidata': 'https://www.wikidata.org/wiki/Q14905375', 'display_name': 'mitochondrial fusion', 'level': 4, 'score': 0.73132944}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7034798}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6032674}, {'id': 'https://openalex.org/C145488412', 'wikidata': 'https://www.wikidata.org/wiki/Q425007', 'display_name': 'Mitochondrial carrier', 'level': 5, 'score': 0.57133454}, {'id': 'https://openalex.org/C28859421', 'wikidata': 'https://www.wikidata.org/wiki/Q39572', 'display_name': 'Mitochondrion', 'level': 2, 'score': 0.554081}, {'id': 'https://openalex.org/C24530287', 'wikidata': 'https://www.wikidata.org/wiki/Q424204', 'display_name': 'Transmembrane protein', 'level': 3, 'score': 0.527027}, {'id': 'https://openalex.org/C159382241', 'wikidata': 'https://www.wikidata.org/wiki/Q85289163', 'display_name': 'Translocase of the inner membrane', 'level': 5, 'score': 0.51316124}, {'id': 'https://openalex.org/C74897846', 'wikidata': 'https://www.wikidata.org/wiki/Q6881870', 'display_name': 'Mitochondrial membrane transport protein', 'level': 4, 'score': 0.4940472}, {'id': 'https://openalex.org/C75385678', 'wikidata': 'https://www.wikidata.org/wiki/Q4896390', 'display_name': 'Inner mitochondrial membrane', 'level': 3, 'score': 0.43827003}, {'id': 'https://openalex.org/C55988834', 'wikidata': 'https://www.wikidata.org/wiki/Q903650', 'display_name': 'Coiled coil', 'level': 2, 'score': 0.41821188}, {'id': 'https://openalex.org/C118892022', 'wikidata': 'https://www.wikidata.org/wiki/Q7834587', 'display_name': 'Transmembrane domain', 'level': 3, 'score': 0.4145558}, {'id': 'https://openalex.org/C146587185', 'wikidata': 'https://www.wikidata.org/wiki/Q258248', 'display_name': 'Bacterial outer membrane', 'level': 4, 'score': 0.3936866}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2764089}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.14056867}, {'id': 'https://openalex.org/C24586158', 'wikidata': 'https://www.wikidata.org/wiki/Q27075', 'display_name': 'Mitochondrial DNA', 'level': 3, 'score': 0.13295245}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.07272914}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017434', 'descriptor_name': 'Protein Structure, Tertiary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002458', 'descriptor_name': 'Cell Fractionation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020558', 'descriptor_name': 'GTP Phosphohydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000145', 'qualifier_name': 'classification', 'is_major_topic': False}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008870', 'descriptor_name': 'Microtubules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D008928', 'descriptor_name': 'Mitochondria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D033681', 'descriptor_name': 'Mitochondrial Membrane Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000145', 'qualifier_name': 'classification', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D024101', 'descriptor_name': 'Mitochondrial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010802', 'descriptor_name': 'Phylogeny', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1242/jcs.115.8.1663', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S5677253', 'display_name': 'Journal of Cell Science', 'issn_l': '0021-9533', 'issn': ['0021-9533', '1477-9137'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11950885', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W1493752155', 'https://openalex.org/W1554250492', 'https://openalex.org/W1561484646', 'https://openalex.org/W1822252127', 'https://openalex.org/W1826524642', 'https://openalex.org/W1974980101', 'https://openalex.org/W1977033097', 'https://openalex.org/W1977104543', 'https://openalex.org/W1977175416', 'https://openalex.org/W1980103053', 'https://openalex.org/W1980183100', 'https://openalex.org/W2003346050', 'https://openalex.org/W2008005699', 'https://openalex.org/W2008560382', 'https://openalex.org/W2014229034', 'https://openalex.org/W2017455861', 'https://openalex.org/W2024645073', 'https://openalex.org/W2034767282', 'https://openalex.org/W2035294162', 'https://openalex.org/W2046353863', 'https://openalex.org/W2049775377', 'https://openalex.org/W2052074631', 'https://openalex.org/W2052607700', 'https://openalex.org/W205578041', 'https://openalex.org/W2060811345', 'https://openalex.org/W2060913542', 'https://openalex.org/W2064488492', 'https://openalex.org/W2067322059', 'https://openalex.org/W2068247528', 'https://openalex.org/W2072087702', 'https://openalex.org/W2072815455', 'https://openalex.org/W2085058400', 'https://openalex.org/W2094113524', 'https://openalex.org/W2101871915', 'https://openalex.org/W2106882534', 'https://openalex.org/W2110931950', 'https://openalex.org/W2116038950', 'https://openalex.org/W2123779991', 'https://openalex.org/W2137424160', 'https://openalex.org/W2139861422', 'https://openalex.org/W2144846851', 'https://openalex.org/W2147207574', 'https://openalex.org/W2158714788', 'https://openalex.org/W2163403085', 'https://openalex.org/W2170929691'], 'related_works': ['https://openalex.org/W4205163367', 'https://openalex.org/W4200372688', 'https://openalex.org/W3201099112', 'https://openalex.org/W2389449182', 'https://openalex.org/W2279006889', 'https://openalex.org/W2223837994', 'https://openalex.org/W2018502225', 'https://openalex.org/W2007583759', 'https://openalex.org/W1603070399', 'https://openalex.org/W1541059618'], 'abstract_inverted_index': {'Two': [0], 'human': [1], 'Fzo-homologs,': [2], 'mitofusins': [3], 'Mfn1': [4], 'and': [5, 11, 32, 41, 51, 98, 124, 189, 200], 'Mfn2,': [6, 96], 'are': [7, 47, 104, 118], 'shown': [8], 'by': [9, 81], 'RT-PCR': [10], 'western': [12], 'blot': [13], 'to': [14, 49, 57, 68, 73, 122, 145], 'be': [15], 'ubiquitous': [16], 'mitochondrial': [17, 108, 184, 191], 'proteins.': [18], 'Protease': [19], 'digestion': [20], 'experiments': [21], 'reveal': [22], 'that': [23, 132, 170], 'Mfn2': [24, 45, 63, 65, 171], 'is': [25, 66, 79, 153, 159], 'an': [26], 'outer': [27, 201], 'membrane': [28], 'protein': [29, 126], 'with': [30, 137, 149], 'N-terminal': [31], 'C-terminal': [33, 42, 77], 'domains': [34, 43, 55, 94, 117, 135], 'exposed': [35], 'towards': [36], 'the': [37, 58, 69, 76, 101, 156, 164, 177, 182, 195, 198], 'cytosol.': [38], 'The': [39, 92], 'transmembrane': [40, 102], 'of': [44, 53, 61, 84, 95, 100, 112, 114, 163, 181, 197], '(Mfn2-TMCT)': [46], 'targeted': [48, 67, 121], 'mitochondria': [50, 74, 123, 146, 175], 'deletion': [52], 'these': [54, 133], 'leads': [56], 'cytosolic': [59], 'localization': [60], 'truncated': [62], '(Mfn2-NT).': [64], 'endoplasmic': [70], 'reticulum': [71], 'or': [72, 87, 142], 'when': [75, 155], 'domain': [78, 158], 'replaced': [80], 'short': [82], 'stretches': [83], 'neutral/hydrophobic': [85], '(Mfn2-IYFFT)': [86], 'polar/basic': [88], '(Mfn2-RRD)': [89], 'amino': [90], 'acids.': [91], 'coiled-coil': [93, 116, 134, 157], 'upstream': [97], 'downstream': [99], 'domain,': [103], 'also': [105, 168], 'important': [106], 'for': [107], 'targeting:': [109], 'Mfn2-mutants': [110], 'deleted': [111, 160], 'any': [113, 162], 'its': [115], 'only': [119], 'partially': [120], 'significant': [125], 'amounts': [127], 'remain': [128], 'cytosolic.': [129], 'We': [130, 167], 'show': [131], 'interact': [136], 'each': [138], 'other:': [139], 'mistargeted': [140], 'Mfn2-NT': [141], 'Mfn2-IYFFT': [143], 'localize': [144], 'if': [147], 'co-expressed': [148], 'Mfn2-TMCT.': [150], 'This': [151], 'relocalization': [152], 'abolished': [154], 'in': [161, 176], 'co-transfected': [165], 'molecules.': [166], 'found': [169], 'can': [172], 'cluster': [173], 'active': [174], 'perinuclear': [178], 'region': [179], 'independently': [180], 'cytoskeleton,bring': [183], 'membranes': [185], 'into': [186], 'close': [187], 'contact': [188], 'modify': [190], 'structure,': [192], 'without': [193], 'disturbing': [194], 'integrity': [196], 'inner': [199], 'membrane.': [202]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2117041194', 'counts_by_year': [{'year': 2024, 'cited_by_count': 24}, {'year': 2023, 'cited_by_count': 17}, {'year': 2022, 'cited_by_count': 17}, {'year': 2021, 'cited_by_count': 23}, {'year': 2020, 'cited_by_count': 27}, {'year': 2019, 'cited_by_count': 31}, {'year': 2018, 'cited_by_count': 27}, {'year': 2017, 'cited_by_count': 22}, {'year': 2016, 'cited_by_count': 23}, {'year': 2015, 'cited_by_count': 22}, {'year': 2014, 'cited_by_count': 19}, {'year': 2013, 'cited_by_count': 24}, {'year': 2012, 'cited_by_count': 33}], 'updated_date': '2024-12-19T02:32:07.927596', 'created_date': '2016-06-24'}