Publication Information

{'id': 'https://openalex.org/W2116902406', 'doi': 'https://doi.org/10.1084/jem.188.6.1105', 'title': 'Major Histocompatibility Complex Class I Viral Antigen Processing in the Secretory Pathway Defined by the <i>trans</i>-Golgi Network Protease Furin', 'display_name': 'Major Histocompatibility Complex Class I Viral Antigen Processing in the Secretory Pathway Defined by the <i>trans</i>-Golgi Network Protease Furin', 'publication_year': 1998, 'publication_date': '1998-09-21', 'ids': {'openalex': 'https://openalex.org/W2116902406', 'doi': 'https://doi.org/10.1084/jem.188.6.1105', 'mag': '2116902406', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9743529', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2212533'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.188.6.1105', 'pdf_url': 'http://jem.rupress.org/content/jem/188/6/1105.full.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://jem.rupress.org/content/jem/188/6/1105.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085138063', 'display_name': 'B. Gil-Torregrosa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801357902', 'display_name': 'Instituto de Salud Carlos III', 'ror': 'https://ror.org/00ca2c886', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801357902', 'https://openalex.org/I4387152914']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Beatriz C. Gil-Torregrosa', 'raw_affiliation_strings': ['From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain', 'institution_ids': ['https://openalex.org/I2801357902']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008590684', 'display_name': 'A. Raúl Castaño', 'orcid': 'https://orcid.org/0000-0003-2107-8862'}, 'institutions': [{'id': 'https://openalex.org/I2801357902', 'display_name': 'Instituto de Salud Carlos III', 'ror': 'https://ror.org/00ca2c886', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801357902', 'https://openalex.org/I4387152914']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'A. Raúl Castaño', 'raw_affiliation_strings': ['From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain', 'institution_ids': ['https://openalex.org/I2801357902']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5006517831', 'display_name': 'Margarita Del Val', 'orcid': 'https://orcid.org/0000-0001-6769-4279'}, 'institutions': [{'id': 'https://openalex.org/I2801357902', 'display_name': 'Instituto de Salud Carlos III', 'ror': 'https://ror.org/00ca2c886', 'country_code': 'ES', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801357902', 'https://openalex.org/I4387152914']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Margarita Del \u2009Val', 'raw_affiliation_strings': ['From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'From the Centro Nacional de Biología Fundamental, Instituto de Salud Carlos III, 28220 Madrid, Spain', 'institution_ids': ['https://openalex.org/I2801357902']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 4.996, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 82, 'citation_normalized_percentile': {'value': 0.904485, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '188', 'issue': '6', 'first_page': '1105', 'last_page': '1116'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10340', 'display_name': 'Hepatitis B Virus Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10340', 'display_name': 'Hepatitis B Virus Studies', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin and proteasome pathways', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10294', 'display_name': 'Cell death mechanisms and regulation', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/antigen-processing', 'display_name': 'Antigen processing', 'score': 0.8907454}, {'id': 'https://openalex.org/keywords/furin', 'display_name': 'Furin', 'score': 0.7464483}, {'id': 'https://openalex.org/keywords/cross-presentation', 'display_name': 'Cross-Presentation', 'score': 0.6459151}], 'concepts': [{'id': 'https://openalex.org/C108249834', 'wikidata': 'https://www.wikidata.org/wiki/Q3922363', 'display_name': 'Antigen processing', 'level': 5, 'score': 0.8907454}, {'id': 'https://openalex.org/C22845430', 'wikidata': 'https://www.wikidata.org/wiki/Q224879', 'display_name': 'Transporter associated with antigen processing', 'level': 5, 'score': 0.8308716}, {'id': 'https://openalex.org/C83464605', 'wikidata': 'https://www.wikidata.org/wiki/Q575296', 'display_name': 'Antigen presentation', 'level': 4, 'score': 0.7736828}, {'id': 'https://openalex.org/C2777265534', 'wikidata': 'https://www.wikidata.org/wiki/Q14916427', 'display_name': 'Furin', 'level': 3, 'score': 0.7464483}, {'id': 'https://openalex.org/C2778973524', 'wikidata': 'https://www.wikidata.org/wiki/Q3910755', 'display_name': 'Cross-presentation', 'level': 5, 'score': 0.6459151}, {'id': 'https://openalex.org/C119062480', 'wikidata': 'https://www.wikidata.org/wiki/Q83181', 'display_name': 'Golgi apparatus', 'level': 3, 'score': 0.60487926}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5924527}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.5805631}, {'id': 'https://openalex.org/C170627219', 'wikidata': 'https://www.wikidata.org/wiki/Q13218497', 'display_name': 'MHC class I', 'level': 4, 'score': 0.55081546}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.532065}, {'id': 'https://openalex.org/C6492254', 'wikidata': 'https://www.wikidata.org/wiki/Q84230', 'display_name': 'Secretory pathway', 'level': 4, 'score': 0.5138338}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.502275}, {'id': 'https://openalex.org/C207936829', 'wikidata': 'https://www.wikidata.org/wiki/Q423163', 'display_name': 'Major histocompatibility complex', 'level': 3, 'score': 0.47059405}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.34576684}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23607293}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.17787668}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.07302061}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D017951', 'descriptor_name': 'Antigen Presentation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006183', 'descriptor_name': 'H-2 Antigens', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D013381', 'descriptor_name': 'Subtilisins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D018528', 'descriptor_name': 'ATP-Binding Cassette Transporters', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003587', 'descriptor_name': 'Cytomegalovirus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D045683', 'descriptor_name': 'Furin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D006056', 'descriptor_name': 'Golgi Apparatus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006183', 'descriptor_name': 'H-2 Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006513', 'descriptor_name': 'Hepatitis B e Antigens', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D006513', 'descriptor_name': 'Hepatitis B e Antigens', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006513', 'descriptor_name': 'Hepatitis B e Antigens', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006513', 'descriptor_name': 'Hepatitis B e Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017874', 'descriptor_name': 'Immediate-Early Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009842', 'descriptor_name': 'Oligopeptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046988', 'descriptor_name': 'Proteasome Endopeptidase Complex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011499', 'descriptor_name': 'Protein Processing, Post-Translational', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D011499', 'descriptor_name': 'Protein Processing, Post-Translational', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013381', 'descriptor_name': 'Subtilisins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013381', 'descriptor_name': 'Subtilisins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.188.6.1105', 'pdf_url': 'http://jem.rupress.org/content/jem/188/6/1105.full.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2212533', 'pdf_url': 'https://europepmc.org/articles/pmc2212533?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212533', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9743529', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.188.6.1105', 'pdf_url': 'http://jem.rupress.org/content/jem/188/6/1105.full.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.5, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1526952883', 'https://openalex.org/W1556986209', 'https://openalex.org/W1624197021', 'https://openalex.org/W1885047062', 'https://openalex.org/W1976601347', 'https://openalex.org/W1977007393', 'https://openalex.org/W1977889843', 'https://openalex.org/W1981726862', 'https://openalex.org/W1984247755', 'https://openalex.org/W1986342078', 'https://openalex.org/W1990997069', 'https://openalex.org/W1991840178', 'https://openalex.org/W2008744347', 'https://openalex.org/W2009703634', 'https://openalex.org/W2019993505', 'https://openalex.org/W2021289499', 'https://openalex.org/W2022330696', 'https://openalex.org/W2033531531', 'https://openalex.org/W2035891785', 'https://openalex.org/W2041871326', 'https://openalex.org/W2043825401', 'https://openalex.org/W2055749616', 'https://openalex.org/W2066284211', 'https://openalex.org/W2070316569', 'https://openalex.org/W2071534681', 'https://openalex.org/W2071901140', 'https://openalex.org/W2077147012', 'https://openalex.org/W2077861376', 'https://openalex.org/W2078750081', 'https://openalex.org/W2083516848', 'https://openalex.org/W2087137589', 'https://openalex.org/W2092891127', 'https://openalex.org/W2093736722', 'https://openalex.org/W2096535057', 'https://openalex.org/W2100037166', 'https://openalex.org/W2100347471', 'https://openalex.org/W2106110287', 'https://openalex.org/W2108442888', 'https://openalex.org/W2112584948', 'https://openalex.org/W2113736802', 'https://openalex.org/W2115405633', 'https://openalex.org/W2117129326', 'https://openalex.org/W2125913713', 'https://openalex.org/W2129914448', 'https://openalex.org/W2135854380', 'https://openalex.org/W2147202630', 'https://openalex.org/W2149285527', 'https://openalex.org/W2152334278', 'https://openalex.org/W2152546316', 'https://openalex.org/W2155513663', 'https://openalex.org/W2170402078', 'https://openalex.org/W2178503716', 'https://openalex.org/W4210821890', 'https://openalex.org/W4252620743'], 'related_works': ['https://openalex.org/W4306154390', 'https://openalex.org/W4205787100', 'https://openalex.org/W2810876386', 'https://openalex.org/W2783846205', 'https://openalex.org/W2615239704', 'https://openalex.org/W2138820414', 'https://openalex.org/W2116902406', 'https://openalex.org/W2053346961', 'https://openalex.org/W2031160342', 'https://openalex.org/W1631812628'], 'abstract_inverted_index': {'Classical': [0], 'antigen': [1, 33, 128, 165, 172, 200], 'presentation': [2, 34, 61, 101, 145], 'by': [3, 17, 29, 188], 'major': [4], 'histocompatibility': [5], 'complex': [6], 'class': [7, 59, 92], 'I': [8, 60, 93], 'molecules': [9], 'involves': [10], 'cytosolic': [11], 'processing': [12, 39, 135, 173], 'of': [13, 21, 40, 62, 65, 98, 117, 121, 148, 153], 'endogenously': [14], 'synthesized': [15], 'antigens': [16, 67], 'proteasomes': [18], 'and': [19, 119, 132, 164], 'translocation': [20], 'processed': [22], 'peptides': [23, 89], 'into': [24], 'the': [25, 45, 56, 69, 96, 112, 124, 139, 154, 177, 189], 'endoplasmic': [26], 'reticulum': [27], '(ER)': [28], 'transporters': [30], 'associated': [31], 'with': [32, 108, 180], '(TAP).': [35], 'Alternative': [36], 'pathways': [37], 'for': [38, 58, 90, 184, 199], 'endogenous': [41, 91], 'antigens,': [42], 'generally': [43], 'involving': [44], 'ER,': [46], 'have': [47], 'been': [48], 'suggested': [49], 'but': [50, 151], 'not': [51], 'fully': [52], 'proved.': [53], 'We': [54, 72], 'analyzed': [55], 'potential': [57], 'proteolytic': [63, 185], 'maturation': [64, 110, 118, 131, 163, 186], 'secretory': [66, 79, 125, 178], 'in': [68, 95, 138, 176], 'exocytic': [70], 'pathway.': [71], 'found': [73], 'that': [74], 'hepatitis': [75], 'B': [76], '(HB)': [77], 'virus': [78], 'core': [80], 'protein': [81, 109], 'HBe': [82, 122, 162], 'can': [83], 'efficiently': [84], 'deliver': [85], 'COOH-terminally': [86], 'located': [87, 175], 'antigenic': [88], 'loading': [94], 'absence': [97], 'TAP.': [99], 'Antigen': [100, 144], 'to': [102], 'specific': [103], 'cytotoxic': [104], 'T': [105], 'lymphocytes': [106], 'correlates': [107], 'at': [111], 'COOH': [113], 'terminus,': [114], 'since': [115], 'modification': [116], 'transport': [120], 'through': [123], 'pathway': [126, 174], 'alters': [127], 'presentation.': [129, 166, 201], 'Both': [130], 'a': [133, 170, 181], 'necessary': [134], 'step': [136], 'occur': [137], 'Golgi': [140], 'or': [141], 'post-Golgi': [142], 'compartment.': [143], 'is': [146], 'independent': [147], 'proteasome': [149], 'activity,': [150], 'inhibitors': [152], 'trans-Golgi': [155], 'network': [156], 'resident': [157], 'protease': [158, 191], 'furin': [159, 194], 'inhibit': [160], 'both': [161], 'These': [167], 'results': [168], 'define': [169], 'new': [171], 'route,': [179], 'central': [182], 'role': [183], 'mediated': [187], 'subtilisin': [190], 'family': [192], 'member': [193], 'as': [195], 'an': [196], 'efficient': [197], 'source': [198]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2116902406', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2025-01-08T00:48:39.975726', 'created_date': '2016-06-24'}