Publication Information

{'id': 'https://openalex.org/W2116492181', 'doi': 'https://doi.org/10.3389/fncel.2014.00211', 'title': 'Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease', 'display_name': 'Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease', 'publication_year': 2014, 'publication_date': '2014-08-04', 'ids': {'openalex': 'https://openalex.org/W2116492181', 'doi': 'https://doi.org/10.3389/fncel.2014.00211', 'mag': '2116492181', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25136294', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4120694'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fncel.2014.00211', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fncel.2014.00211/pdf', 'source': {'id': 'https://openalex.org/S36653316', 'display_name': 'Frontiers in Cellular Neuroscience', 'issn_l': '1662-5102', 'issn': ['1662-5102'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.frontiersin.org/articles/10.3389/fncel.2014.00211/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5016445424', 'display_name': 'Ricardo Cabezas', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Ricardo Cabezas', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033346496', 'display_name': 'Marcos Fidel Ávila', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Marcos Ã\x81vila', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061562222', 'display_name': 'Janneth González', 'orcid': 'https://orcid.org/0000-0003-4482-256X'}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Janneth Gonzalez', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088863792', 'display_name': 'Ramon dos Santos El-Bachá', 'orcid': 'https://orcid.org/0000-0002-3321-0392'}, 'institutions': [{'id': 'https://openalex.org/I126158947', 'display_name': 'Universidade Federal da Bahia', 'ror': 'https://ror.org/03k3p7647', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I126158947']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Ramon Santos El-Bachá', 'raw_affiliation_strings': ['Departamento de Biofunção, Universidade Federal da Bahia, Salvador, Brazil'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Biofunção, Universidade Federal da Bahia, Salvador, Brazil', 'institution_ids': ['https://openalex.org/I126158947']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5096783814', 'display_name': 'Eliana Báez', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Eliana Báez', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025650833', 'display_name': 'Luis Miguel García‐Segura', 'orcid': 'https://orcid.org/0000-0002-2450-2916'}, 'institutions': [{'id': 'https://openalex.org/I2184545', 'display_name': 'Instituto Cajal', 'ror': 'https://ror.org/012gwbh42', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I134820265', 'https://openalex.org/I2184545']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Luis Miguel GarcÃ\xada-Segura', 'raw_affiliation_strings': ['Instituto Cajal (CSIC), Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Instituto Cajal (CSIC), Madrid, Spain', 'institution_ids': ['https://openalex.org/I2184545']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046854689', 'display_name': 'Juan Camilo Jurado-Coronel', 'orcid': 'https://orcid.org/0000-0003-4167-8726'}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Juan Camilo Jurado Coronel', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001157199', 'display_name': 'Francisco Capani', 'orcid': 'https://orcid.org/0000-0003-0342-0628'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'Francisco Capani', 'raw_affiliation_strings': ['Laboratorio de Citoarquitectura y Plasticidad Neuronal, Facultad de Medicina, Instituto de Investigaciones cardiológicas Prof. Dr. Alberto C. Taquini (ININCA), UBA-CONICET, Buenos Aires Argentina.'], 'affiliations': [{'raw_affiliation_string': 'Laboratorio de Citoarquitectura y Plasticidad Neuronal, Facultad de Medicina, Instituto de Investigaciones cardiológicas Prof. Dr. Alberto C. Taquini (ININCA), UBA-CONICET, Buenos Aires Argentina.', 'institution_ids': ['https://openalex.org/I151201029']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025061606', 'display_name': 'Gloria Patricia Cardona‐Gómez', 'orcid': 'https://orcid.org/0000-0002-3814-4494'}, 'institutions': [{'id': 'https://openalex.org/I35961687', 'display_name': 'Universidad de Antioquia', 'ror': 'https://ror.org/03bp5hc83', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I35961687']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'Gloria Patricia Cardona-Gomez', 'raw_affiliation_strings': ['Cellular and Molecular Neurobiology Area, Group of Neuroscience of Antioquia, Faculty of Medicine, SIU, University of Antioquia UdeA Medellín, Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Cellular and Molecular Neurobiology Area, Group of Neuroscience of Antioquia, Faculty of Medicine, SIU, University of Antioquia UdeA Medellín, Colombia.', 'institution_ids': ['https://openalex.org/I35961687']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5017960386', 'display_name': 'George E. Barreto', 'orcid': 'https://orcid.org/0000-0002-6644-1971'}, 'institutions': [{'id': 'https://openalex.org/I233745408', 'display_name': 'Pontificia Universidad Javeriana', 'ror': 'https://ror.org/03etyjw28', 'country_code': 'CO', 'type': 'education', 'lineage': ['https://openalex.org/I233745408']}], 'countries': ['CO'], 'is_corresponding': False, 'raw_author_name': 'George E. Barreto', 'raw_affiliation_strings': ['Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.'], 'affiliations': [{'raw_affiliation_string': 'Departamento de Nutricion y Bioquimica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogota D.C., Colombia.', 'institution_ids': ['https://openalex.org/I233745408']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'apc_paid': {'value': 2950, 'currency': 'USD', 'value_usd': 2950, 'provenance': 'doaj'}, 'fwci': 3.275, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 374, 'citation_normalized_percentile': {'value': 0.996116, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '8', 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11872', 'display_name': 'Barrier Structure and Function Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11872', 'display_name': 'Barrier Structure and Function Studies', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13481', 'display_name': 'Neurological diseases and metabolism', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/gliosis', 'display_name': 'Gliosis', 'score': 0.5747246}, {'id': 'https://openalex.org/keywords/homeostasis', 'display_name': 'Homeostasis', 'score': 0.41487893}], 'concepts': [{'id': 'https://openalex.org/C2778402981', 'wikidata': 'https://www.wikidata.org/wiki/Q221694', 'display_name': 'Blood–brain barrier', 'level': 3, 'score': 0.8269712}, {'id': 'https://openalex.org/C2777542381', 'wikidata': 'https://www.wikidata.org/wiki/Q502961', 'display_name': 'Astrocyte', 'level': 3, 'score': 0.8116951}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.7661816}, {'id': 'https://openalex.org/C2777682930', 'wikidata': 'https://www.wikidata.org/wiki/Q1531490', 'display_name': 'Gliosis', 'level': 2, 'score': 0.5747246}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.49028853}, {'id': 'https://openalex.org/C2779734285', 'wikidata': 'https://www.wikidata.org/wiki/Q11085', 'display_name': "Parkinson's disease", 'level': 3, 'score': 0.48273844}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4359747}, {'id': 'https://openalex.org/C63645605', 'wikidata': 'https://www.wikidata.org/wiki/Q103191', 'display_name': 'Homeostasis', 'level': 2, 'score': 0.41487893}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4009775}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.31248188}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.2844772}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.20118102}], 'mesh': [], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fncel.2014.00211', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fncel.2014.00211/pdf', 'source': {'id': 'https://openalex.org/S36653316', 'display_name': 'Frontiers in Cellular Neuroscience', 'issn_l': '1662-5102', 'issn': ['1662-5102'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4120694', 'pdf_url': 'https://europepmc.org/articles/pmc4120694?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10261/152782', 'pdf_url': 'https://digital.csic.es/bitstream/10261/152782/1/Astrocytic%20modulation%20of%20blood%20brain%20barrier.pdf', 'source': {'id': 'https://openalex.org/S4306401639', 'display_name': 'DIGITAL.CSIC (Spanish National Research Council (CSIC))', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I134820265', 'host_organization_name': 'Consejo Superior de Investigaciones Científicas', 'host_organization_lineage': ['https://openalex.org/I134820265'], 'host_organization_lineage_names': ['Consejo Superior de Investigaciones Científicas'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120694', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25136294', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3389/fncel.2014.00211', 'pdf_url': 'https://www.frontiersin.org/articles/10.3389/fncel.2014.00211/pdf', 'source': {'id': 'https://openalex.org/S36653316', 'display_name': 'Frontiers in Cellular Neuroscience', 'issn_l': '1662-5102', 'issn': ['1662-5102'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320527', 'host_organization_name': 'Frontiers Media', 'host_organization_lineage': ['https://openalex.org/P4310320527'], 'host_organization_lineage_names': ['Frontiers Media'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.8, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 147, 'referenced_works': ['https://openalex.org/W1485428386', 'https://openalex.org/W1504584187', 'https://openalex.org/W1506045573', 'https://openalex.org/W1574424832', 'https://openalex.org/W162320534', 'https://openalex.org/W1647861543', 'https://openalex.org/W182730751', 'https://openalex.org/W188961659', 'https://openalex.org/W1963766511', 'https://openalex.org/W1964544761', 'https://openalex.org/W1966943736', 'https://openalex.org/W1967127565', 'https://openalex.org/W1968306269', 'https://openalex.org/W1972157709', 'https://openalex.org/W1973563466', 'https://openalex.org/W1978008817', 'https://openalex.org/W1978836458', 'https://openalex.org/W1981128350', 'https://openalex.org/W1981984722', 'https://openalex.org/W1982189761', 'https://openalex.org/W1983166842', 'https://openalex.org/W1983712592', 'https://openalex.org/W1983836947', 'https://openalex.org/W1984474165', 'https://openalex.org/W1984678282', 'https://openalex.org/W1990078383', 'https://openalex.org/W1990195639', 'https://openalex.org/W1992826589', 'https://openalex.org/W1993480869', 'https://openalex.org/W1994548138', 'https://openalex.org/W1994624114', 'https://openalex.org/W1996001296', 'https://openalex.org/W1999215303', 'https://openalex.org/W1999862256', 'https://openalex.org/W2001408101', 'https://openalex.org/W2003323514', 'https://openalex.org/W2003726414', 'https://openalex.org/W2006376003', 'https://openalex.org/W2006610133', 'https://openalex.org/W2006684548', 'https://openalex.org/W2008201895', 'https://openalex.org/W2008321168', 'https://openalex.org/W2008774890', 'https://openalex.org/W2011296674', 'https://openalex.org/W2011907681', 'https://openalex.org/W2012674659', 'https://openalex.org/W2015541518', 'https://openalex.org/W2015616129', 'https://openalex.org/W2016454796', 'https://openalex.org/W2019136933', 'https://openalex.org/W2019682082', 'https://openalex.org/W2021595138', 'https://openalex.org/W2022664682', 'https://openalex.org/W2024189727', 'https://openalex.org/W2026506478', 'https://openalex.org/W2027204298', 'https://openalex.org/W2030588597', 'https://openalex.org/W2031827286', 'https://openalex.org/W2032444015', 'https://openalex.org/W2035995291', 'https://openalex.org/W2039818485', 'https://openalex.org/W2039902359', 'https://openalex.org/W2040407175', 'https://openalex.org/W2042630261', 'https://openalex.org/W2043676089', 'https://openalex.org/W2047853787', 'https://openalex.org/W2047917383', 'https://openalex.org/W2048897966', 'https://openalex.org/W2048975741', 'https://openalex.org/W2049001439', 'https://openalex.org/W2050390944', 'https://openalex.org/W2050996473', 'https://openalex.org/W2053184316', 'https://openalex.org/W2055908419', 'https://openalex.org/W2056856515', 'https://openalex.org/W2057001027', 'https://openalex.org/W2057014510', 'https://openalex.org/W2057258185', 'https://openalex.org/W2058875972', 'https://openalex.org/W2059172386', 'https://openalex.org/W2061001694', 'https://openalex.org/W2061440151', 'https://openalex.org/W2063161813', 'https://openalex.org/W2063430288', 'https://openalex.org/W2064999972', 'https://openalex.org/W2065856656', 'https://openalex.org/W2068400560', 'https://openalex.org/W2068469496', 'https://openalex.org/W2070627442', 'https://openalex.org/W2071967324', 'https://openalex.org/W2073803664', 'https://openalex.org/W2075527716', 'https://openalex.org/W2075591819', 'https://openalex.org/W2076116873', 'https://openalex.org/W2078423766', 'https://openalex.org/W2081260033', 'https://openalex.org/W2088318073', 'https://openalex.org/W2089395709', 'https://openalex.org/W2089529899', 'https://openalex.org/W2091497743', 'https://openalex.org/W2094935740', 'https://openalex.org/W2097634622', 'https://openalex.org/W2098176076', 'https://openalex.org/W2099169014', 'https://openalex.org/W2103825400', 'https://openalex.org/W2104629966', 'https://openalex.org/W2107873445', 'https://openalex.org/W2109270284', 'https://openalex.org/W2109832016', 'https://openalex.org/W2112001901', 'https://openalex.org/W2115600702', 'https://openalex.org/W2116447221', 'https://openalex.org/W2116656618', 'https://openalex.org/W2118661818', 'https://openalex.org/W2120294814', 'https://openalex.org/W2120429648', 'https://openalex.org/W2124892998', 'https://openalex.org/W2125278063', 'https://openalex.org/W2125411036', 'https://openalex.org/W2125970178', 'https://openalex.org/W2127460667', 'https://openalex.org/W2129553803', 'https://openalex.org/W2129567809', 'https://openalex.org/W2133498810', 'https://openalex.org/W2138475390', 'https://openalex.org/W2141298701', 'https://openalex.org/W2142483035', 'https://openalex.org/W2147779395', 'https://openalex.org/W2148992136', 'https://openalex.org/W2150301159', 'https://openalex.org/W2152494586', 'https://openalex.org/W2154414488', 'https://openalex.org/W2154439380', 'https://openalex.org/W2154772731', 'https://openalex.org/W2155075033', 'https://openalex.org/W2156179625', 'https://openalex.org/W2162079087', 'https://openalex.org/W2163240536', 'https://openalex.org/W2167739272', 'https://openalex.org/W2169714384', 'https://openalex.org/W2293877091', 'https://openalex.org/W2301963636', 'https://openalex.org/W2324360399', 'https://openalex.org/W2364391019', 'https://openalex.org/W2523521297', 'https://openalex.org/W4211037293', 'https://openalex.org/W69591616'], 'related_works': ['https://openalex.org/W47424815', 'https://openalex.org/W2883678860', 'https://openalex.org/W2766424950', 'https://openalex.org/W2381638252', 'https://openalex.org/W2080254122', 'https://openalex.org/W2078924802', 'https://openalex.org/W2045543138', 'https://openalex.org/W2036221168', 'https://openalex.org/W1884247838', 'https://openalex.org/W1558073430'], 'abstract_inverted_index': {'TThe': [0], 'blood–brain': [1], 'barrier': [2, 114, 154], '(BBB)': [3], 'is': [4, 32, 138], 'a': [5, 43, 99, 107, 139, 149, 157], 'tightly': [6], 'regulated': [7], 'interface': [8], 'in': [9, 20, 109, 118, 160, 173, 180, 197, 210], 'the': [10, 16, 24, 28, 47, 54, 59, 68, 72, 75, 78, 102, 110, 113, 120, 133, 153, 168, 174, 177, 181, 192, 202, 208], 'Central': [11], 'Nervous': [12], 'System': [13], 'that': [14, 41, 65, 132], 'regulates': [15], 'exchange': [17], 'of': [18, 35, 58, 74, 80, 101, 112, 135, 142, 170, 176, 183, 204], 'molecules': [19], 'and': [21, 39, 56, 77, 96, 115, 123, 156, 179, 186, 194], 'out': [22], 'from': [23], 'brain': [25, 92], 'thus': [26], 'maintaining': [27], 'CNS': [29], 'homeostasis.': [30], 'It': [31], 'mainly': [33], 'composed': [34], 'endothelial': [36, 121], 'cells,': [37], 'pericytes': [38], 'astrocytes': [40, 143], 'create': [42], 'neurovascular': [44], 'unit': [45], 'with': [46], 'adjacent': [48], 'neurons.': [49], 'Astrocytes': [50], 'are': [51], 'essential': [52], 'for': [53, 207], 'formation': [55, 79], 'maintenance': [57], 'BBB': [60, 76, 103, 145, 209], 'by': [61], 'providing': [62], 'secreted': [63], 'factors': [64], 'lead': [66], 'to': [67], 'adequate': [69], 'association': [70], 'between': [71], 'cells': [73, 122], 'strong': [81], 'tight': [82], 'junctions.': [83], 'Under': [84], 'neurological': [85], 'disorders,': [86], 'such': [87], 'as': [88], 'chronic': [89], 'cerebral': [90], 'ischemia,': [91], 'trauma,': [93], 'Epilepsy,': [94], 'Alzheimer': [95], 'Parkinson´s': [97, 184], 'Diseases,': [98], 'disruption': [100], 'takes': [104], 'place,': [105], 'involving': [106], 'lost': [108], 'permeability': [111], 'phenotypical': [116], 'changes': [117], 'both': [119], 'astrocytes.': [124], 'In': [125, 163], 'this': [126, 164], 'aspect,': [127], 'it': [128], 'has': [129, 148], 'been': [130], 'established': [131], 'process': [134], 'reactive': [136], 'gliosis': [137], 'common': [140], 'feature': [141], 'during': [144], 'disruption,': [146], 'which': [147], 'detrimental': [150], 'effect': [151], 'on': [152], 'function': [155], 'subsequent': [158], 'damage': [159], 'neuronal': [161], 'survival.': [162], 'review': [165], 'we': [166, 190], 'discuss': [167], 'implications': [169], 'astrocyte': [171, 198], 'functions': [172], 'protection': [175, 199], 'BBB,': [178], 'development': [182, 203], 'disease': [185], 'related': [187], 'disorders.': [188], 'Additionally,': [189], 'highlight': [191], 'current': [193], 'future': [195], 'strategies': [196], 'aimed': [200], 'at': [201], 'restorative': [205], 'therapies': [206], 'pathological': [211], 'conditions.': [212]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2116492181', 'counts_by_year': [{'year': 2024, 'cited_by_count': 46}, {'year': 2023, 'cited_by_count': 42}, {'year': 2022, 'cited_by_count': 45}, {'year': 2021, 'cited_by_count': 49}, {'year': 2020, 'cited_by_count': 35}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 36}, {'year': 2017, 'cited_by_count': 28}, {'year': 2016, 'cited_by_count': 34}, {'year': 2015, 'cited_by_count': 20}, {'year': 2014, 'cited_by_count': 4}], 'updated_date': '2024-12-19T14:02:43.041424', 'created_date': '2016-06-24'}