Publication Information

{'id': 'https://openalex.org/W2116217428', 'doi': 'https://doi.org/10.1002/jat.2550120405', 'title': 'Toxicology of carbaryl and aldicarb on brain and limb cultures of chick embryos', 'display_name': 'Toxicology of carbaryl and aldicarb on brain and limb cultures of chick embryos', 'publication_year': 1992, 'publication_date': '1992-08-01', 'ids': {'openalex': 'https://openalex.org/W2116217428', 'doi': 'https://doi.org/10.1002/jat.2550120405', 'mag': '2116217428', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1430773'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jat.2550120405', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S81851855', 'display_name': 'Journal of Applied Toxicology', 'issn_l': '0260-437X', 'issn': ['0260-437X', '1099-1263'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5076126521', 'display_name': 'Miranda Farage‐Elawar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I859038795', 'display_name': 'Virginia Tech', 'ror': 'https://ror.org/02smfhw86', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I859038795']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Farage‐Elawar', 'raw_affiliation_strings': ['VA/MD Regional College of Veterinary Medicine, Department of Biomedical Sciences, Virginia Tech, Blacksburg 24061.'], 'affiliations': [{'raw_affiliation_string': 'VA/MD Regional College of Veterinary Medicine, Department of Biomedical Sciences, Virginia Tech, Blacksburg 24061.', 'institution_ids': ['https://openalex.org/I859038795']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110279897', 'display_name': 'Teresa K. Rowles', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I39822340', 'display_name': 'Virginia–Maryland College of Veterinary Medicine', 'ror': 'https://ror.org/010prmy50', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39822340', 'https://openalex.org/I66946132', 'https://openalex.org/I859038795']}, {'id': 'https://openalex.org/I859038795', 'display_name': 'Virginia Tech', 'ror': 'https://ror.org/02smfhw86', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I859038795']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T. K. Rowles', 'raw_affiliation_strings': ['VA/MD Regional College of Veterinary Medicine, Department of Biomedical Sciences, Virginia Tech, Blacksburg, VA 24061, USA'], 'affiliations': [{'raw_affiliation_string': 'VA/MD Regional College of Veterinary Medicine, Department of Biomedical Sciences, Virginia Tech, Blacksburg, VA 24061, USA', 'institution_ids': ['https://openalex.org/I39822340', 'https://openalex.org/I859038795']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4220, 'currency': 'USD', 'value_usd': 4220, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.643184, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 75, 'max': 76}, 'biblio': {'volume': '12', 'issue': '4', 'first_page': '239', 'last_page': '244'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11641', 'display_name': 'Insect and Pesticide Research', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11641', 'display_name': 'Insect and Pesticide Research', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11075', 'display_name': 'Insect Resistance and Genetics', 'score': 0.9916, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10875', 'display_name': 'Pesticide Exposure and Toxicity', 'score': 0.9878, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/carbaryl', 'display_name': 'Carbaryl', 'score': 0.98558676}, {'id': 'https://openalex.org/keywords/aldicarb', 'display_name': 'Aldicarb', 'score': 0.96758044}, {'id': 'https://openalex.org/keywords/carbamate', 'display_name': 'Carbamate', 'score': 0.8547106}, {'id': 'https://openalex.org/keywords/neutral-red', 'display_name': 'Neutral red', 'score': 0.48551536}], 'concepts': [{'id': 'https://openalex.org/C2776051353', 'wikidata': 'https://www.wikidata.org/wiki/Q415090', 'display_name': 'Carbaryl', 'level': 3, 'score': 0.98558676}, {'id': 'https://openalex.org/C2778712592', 'wikidata': 'https://www.wikidata.org/wiki/Q63088093', 'display_name': 'Aldicarb', 'level': 3, 'score': 0.96758044}, {'id': 'https://openalex.org/C2779303437', 'wikidata': 'https://www.wikidata.org/wiki/Q422899', 'display_name': 'Carbamate', 'level': 2, 'score': 0.8547106}, {'id': 'https://openalex.org/C109316439', 'wikidata': 'https://www.wikidata.org/wiki/Q246181', 'display_name': 'Cytotoxicity', 'level': 3, 'score': 0.68846434}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.56765085}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5118496}, {'id': 'https://openalex.org/C2780484033', 'wikidata': 'https://www.wikidata.org/wiki/Q417515', 'display_name': 'Neutral red', 'level': 4, 'score': 0.48551536}, {'id': 'https://openalex.org/C33070731', 'wikidata': 'https://www.wikidata.org/wiki/Q7218', 'display_name': 'Toxicology', 'level': 1, 'score': 0.43953285}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.42526558}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33405948}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29502478}, {'id': 'https://openalex.org/C161176658', 'wikidata': 'https://www.wikidata.org/wiki/Q131656', 'display_name': 'Pesticide', 'level': 2, 'score': 0.28300902}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.059241533}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000448', 'descriptor_name': 'Aldicarb', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D012721', 'descriptor_name': 'Carbaryl', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D005121', 'descriptor_name': 'Extremities', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D000448', 'descriptor_name': 'Aldicarb', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D012721', 'descriptor_name': 'Carbaryl', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002642', 'descriptor_name': 'Chick Embryo', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046508', 'descriptor_name': 'Culture Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005121', 'descriptor_name': 'Extremities', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/jat.2550120405', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S81851855', 'display_name': 'Journal of Applied Toxicology', 'issn_l': '0260-437X', 'issn': ['0260-437X', '1099-1263'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1430773', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W1497540956', 'https://openalex.org/W1519258805', 'https://openalex.org/W1965182209', 'https://openalex.org/W1969236043', 'https://openalex.org/W1988522714', 'https://openalex.org/W1995197801', 'https://openalex.org/W2000803201', 'https://openalex.org/W2006029626', 'https://openalex.org/W2013449420', 'https://openalex.org/W2028715151', 'https://openalex.org/W2052777102', 'https://openalex.org/W2064307794', 'https://openalex.org/W2065632045', 'https://openalex.org/W2067163967', 'https://openalex.org/W2234625266', 'https://openalex.org/W2315326690', 'https://openalex.org/W2320079261', 'https://openalex.org/W2404700653', 'https://openalex.org/W2410129681', 'https://openalex.org/W2417547750', 'https://openalex.org/W2613135293', 'https://openalex.org/W4210453461', 'https://openalex.org/W92155286'], 'related_works': ['https://openalex.org/W2521015951', 'https://openalex.org/W2444491411', 'https://openalex.org/W2402905608', 'https://openalex.org/W2384234363', 'https://openalex.org/W2329700827', 'https://openalex.org/W2294972489', 'https://openalex.org/W2116217428', 'https://openalex.org/W2111091569', 'https://openalex.org/W2022148243', 'https://openalex.org/W2006029626'], 'abstract_inverted_index': {'Abstract': [0], 'A': [1], 'variety': [2], 'of': [3, 38, 53, 90, 100, 112, 116, 134, 153, 157, 178, 191, 201, 217, 229, 274, 279], 'carbamates': [4, 243], 'have': [5, 244], 'been': [6], 'developed': [7], 'since': [8], 'the': [9, 36, 71, 88, 199, 215, 218, 272, 277], '1960s': [10], 'for': [11, 29, 64], 'use': [12], 'as': [13, 107], 'broad‐spectrum': [14], 'insecticides.': [15], 'An': [16], 'easy': [17], 'and': [18, 34, 44, 68, 75, 81, 92, 103, 204, 231, 254, 257], 'inexpensive': [19], 'in': [20, 132, 214, 236], 'vitro': [21, 237], 'assay': [22], 'using': [23, 70], 'chick‐embryo': [24], 'derived': [25], 'cells': [26], 'was': [27, 120, 126, 144, 267], 'examined': [28], 'its': [30], 'capability': [31], 'to': [32, 251, 261, 270], 'screen': [33], 'test': [35], 'toxicity': [37, 273, 278], 'these': [39, 241], 'compounds.': [40], 'Chick': [41], 'embryo': [42], 'brain': [43, 95, 117, 203, 219, 253, 262], 'limb': [45, 139, 173, 205, 222, 255, 264], 'bud': [46], 'cultures': [47, 119], 'were': [48, 84], 'treated': [49], 'with': [50, 58, 248], 'different': [51], 'concentrations': [52, 111, 133, 152, 177, 190], 'either': [54], 'carbaryl': [55, 91, 129, 141, 158, 230, 249, 275], 'or': [56, 59], 'aldicarb': [57, 93, 166, 182, 207, 232, 258], 'without': [60, 142, 167], 'activation': [61], '(±': [62], 'S‐9)': [63], '5': [65], 'days.': [66], 'Viability': [67, 115], 'cytotoxicity': [69, 97, 175, 188], 'neutral': [72, 113], 'red': [73], 'assay,': [74], 'carbamate': [76], 'effects': [77, 89], 'on': [78, 94, 172], 'cell': [79, 96, 118, 174], 'migration': [80], 'colony': [82], 'spread': [83, 200, 216], 'measured.': [85], 'S‐9': [86, 131, 143, 160, 168, 184, 197, 209, 266], 'decreased': [87, 127, 198], 'at': [98, 147, 176, 189], 'exposures': [99], '15–60': [101], 'ppm': [102, 156], '40–200': [104, 179], 'ppm,': [105, 149, 180], 'respectively,': [106], 'indicated': [108], 'by': [109, 123, 128], 'increased': [110], 'red.': [114], 'not': [121, 221], 'altered': [122], 'aldicarb,': [124], 'but': [125, 150, 181, 220, 239], 'plus': [130, 159, 183], '>': [135, 154, 192], '40': [136], 'ppm.': [137, 194], 'In': [138, 164], 'cultures,': [140], 'significantly': [145, 161, 185], 'toxic': [146, 250, 260], '8–25': [148], 'only': [151], '25': [155], 'affected': [162], 'cytotoxicity.': [163], 'contrast,': [165], 'caused': [169, 210], 'no': [170], 'effect': [171], 'reduced': [186], 'cellular': [187], '160': [193], 'Carbaryl': [195], '±': [196, 208], 'both': [202, 252], 'colonies;': [206], 'a': [211, 245], 'significant': [212], 'increase': [213], 'colonies.': [223], 'These': [224], 'results': [225], 'suggest': [226], 'that': [227, 240], 'toxicities': [228], 'can': [233], 'be': [234], 'detected': [235], ',': [238], 'two': [242], 'selective': [246], 'toxicity,': [247], 'buds': [256], 'more': [259, 268], 'than': [263, 276], 'cells.': [265], 'likely': [269], 'decrease': [271], 'aldicarb.': [280]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2116217428', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-12T11:35:09.611231', 'created_date': '2016-06-24'}