Title: Coronary calcifications and serum levels of osteoprotegerin (OPG) matrix Gla protein (MPG) and FETUIN-A (F) in renal transplantation (RTX)
Abstract: and OPG (r=.213; p<.06), and negatively with F (r=-.281; p<.02), but not with MGP. In RTX coronary calcium score was lower than in D (580±1669 vs 1593±3515; p<.07) and significantly related to D vintage (r=.405; p<.004) and OPG (r=.327 p<.02) but not to age or RTX duration. In D the score showed a weak negative correlation with F (r=-.361; p<.06) but not with D vintage or age. The three proteins were not correlated in RTX or in D. Therefore, in RTX serum levels of OPG, MGP and F are normalized; this could indicate a lower risk of ectopic calcifications, compared to D. According to this hypothesis, duration of D but not of RTX was associated with coronary calcification. Serum levels of OPG and of F, but not of MGP, seem to be useful markers of vascular calcification in these patients.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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