Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2114951922', 'doi': 'https://doi.org/10.1016/0092-8674(94)90419-7', 'title': 'High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice', 'display_name': 'High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice', 'publication_year': 1994, 'publication_date': '1994-08-01', 'ids': {'openalex': 'https://openalex.org/W2114951922', 'doi': 'https://doi.org/10.1016/0092-8674(94)90419-7', 'mag': '2114951922', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7520367'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0092-8674(94)90419-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085413195', 'display_name': 'Juan J. Lafaille', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63966007', 'display_name': 'Massachusetts Institute of Technology', 'ror': 'https://ror.org/042nb2s44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63966007']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Juan J. Lafaille', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Department of Biology Massachusetts Institute of Technology Cambridge 02139.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Department of Biology Massachusetts Institute of Technology Cambridge 02139.', 'institution_ids': ['https://openalex.org/I63966007']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066214466', 'display_name': 'Kumiko Nagashima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63966007', 'display_name': 'Massachusetts Institute of Technology', 'ror': 'https://ror.org/042nb2s44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63966007']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kumiko Nagashima', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.', 'institution_ids': ['https://openalex.org/I63966007']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040582134', 'display_name': 'Motoya Katsuki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135598925', 'display_name': 'Kyushu University', 'ror': 'https://ror.org/00p4k0j84', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I135598925']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Motoya Katsuki', 'raw_affiliation_strings': ['Medical Institute of Bioregulation Kyushu University Fukuoka 812 Japan'], 'affiliations': [{'raw_affiliation_string': 'Medical Institute of Bioregulation Kyushu University Fukuoka 812 Japan', 'institution_ids': ['https://openalex.org/I135598925']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5038557565', 'display_name': 'Susumu Tonegawa', 'orcid': 'https://orcid.org/0000-0003-2839-8228'}, 'institutions': [{'id': 'https://openalex.org/I63966007', 'display_name': 'Massachusetts Institute of Technology', 'ror': 'https://ror.org/042nb2s44', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I63966007']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Susumu Tonegawa', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.', 'institution_ids': ['https://openalex.org/I63966007']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 10100, 'currency': 'USD', 'value_usd': 10100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 12.641, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 544, 'citation_normalized_percentile': {'value': 0.999891, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '78', 'issue': '3', 'first_page': '399', 'last_page': '408'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11171', 'display_name': 'Diabetes and associated disorders', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11171', 'display_name': 'Diabetes and associated disorders', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/encephalomyelitis', 'display_name': 'Encephalomyelitis', 'score': 0.53525335}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.93298316}, {'id': 'https://openalex.org/C102230213', 'wikidata': 'https://www.wikidata.org/wiki/Q430117', 'display_name': 'Transgene', 'level': 3, 'score': 0.75008786}, {'id': 'https://openalex.org/C2778486448', 'wikidata': 'https://www.wikidata.org/wiki/Q494066', 'display_name': 'Experimental autoimmune encephalomyelitis', 'level': 3, 'score': 0.7255744}, {'id': 'https://openalex.org/C141035611', 'wikidata': 'https://www.wikidata.org/wiki/Q5532934', 'display_name': 'Genetically modified mouse', 'level': 4, 'score': 0.6293747}, {'id': 'https://openalex.org/C2780876595', 'wikidata': 'https://www.wikidata.org/wiki/Q410974', 'display_name': 'Myelin basic protein', 'level': 4, 'score': 0.6075522}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.55161995}, {'id': 'https://openalex.org/C2777899865', 'wikidata': 'https://www.wikidata.org/wiki/Q1634879', 'display_name': 'Encephalomyelitis', 'level': 3, 'score': 0.53525335}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.49543035}, {'id': 'https://openalex.org/C2780130043', 'wikidata': 'https://www.wikidata.org/wiki/Q192360', 'display_name': 'Autoimmunity', 'level': 3, 'score': 0.4290177}, {'id': 'https://openalex.org/C2778609137', 'wikidata': 'https://www.wikidata.org/wiki/Q105790271', 'display_name': 'Myelin', 'level': 3, 'score': 0.41724437}, {'id': 'https://openalex.org/C2780640218', 'wikidata': 'https://www.wikidata.org/wiki/Q8277', 'display_name': 'Multiple sclerosis', 'level': 2, 'score': 0.313984}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.26732}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.26654872}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.1460639}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.14300317}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.08757192}], 'mesh': [{'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D004679', 'descriptor_name': 'Encephalomyelitis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D018398', 'descriptor_name': 'Homeodomain Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004676', 'descriptor_name': 'Myelin Basic Protein', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D016693', 'descriptor_name': 'Receptors, Antigen, T-Cell, alpha-beta', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003433', 'descriptor_name': 'Crosses, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004679', 'descriptor_name': 'Encephalomyelitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008214', 'descriptor_name': 'Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004676', 'descriptor_name': 'Myelin Basic Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016693', 'descriptor_name': 'Receptors, Antigen, T-Cell, alpha-beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016693', 'descriptor_name': 'Receptors, Antigen, T-Cell, alpha-beta', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0092-8674(94)90419-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7520367', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.63}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 48, 'referenced_works': ['https://openalex.org/W1532866158', 'https://openalex.org/W1535663915', 'https://openalex.org/W1608362877', 'https://openalex.org/W1906640112', 'https://openalex.org/W1966388921', 'https://openalex.org/W1986928676', 'https://openalex.org/W1990204841', 'https://openalex.org/W1996350333', 'https://openalex.org/W1998531275', 'https://openalex.org/W2011658568', 'https://openalex.org/W2013705019', 'https://openalex.org/W2018429509', 'https://openalex.org/W2019638830', 'https://openalex.org/W2021951643', 'https://openalex.org/W2022649266', 'https://openalex.org/W2026789834', 'https://openalex.org/W2031355573', 'https://openalex.org/W2033111998', 'https://openalex.org/W2040595594', 'https://openalex.org/W2044316391', 'https://openalex.org/W2044465435', 'https://openalex.org/W2044578153', 'https://openalex.org/W2049927686', 'https://openalex.org/W2053278781', 'https://openalex.org/W2055485094', 'https://openalex.org/W2062572904', 'https://openalex.org/W2063302591', 'https://openalex.org/W2065745435', 'https://openalex.org/W2080232986', 'https://openalex.org/W2081395451', 'https://openalex.org/W2084189998', 'https://openalex.org/W2085937163', 'https://openalex.org/W2086417745', 'https://openalex.org/W2087024017', 'https://openalex.org/W2088437362', 'https://openalex.org/W2091171997', 'https://openalex.org/W2093635040', 'https://openalex.org/W2108617074', 'https://openalex.org/W2116408074', 'https://openalex.org/W2126232873', 'https://openalex.org/W2128707261', 'https://openalex.org/W2133692536', 'https://openalex.org/W2136389988', 'https://openalex.org/W2140489687', 'https://openalex.org/W2150760619', 'https://openalex.org/W2173694857', 'https://openalex.org/W2326904657', 'https://openalex.org/W2417141046'], 'related_works': ['https://openalex.org/W2916098008', 'https://openalex.org/W2531083419', 'https://openalex.org/W2377679890', 'https://openalex.org/W2090613411', 'https://openalex.org/W2087355971', 'https://openalex.org/W2060132222', 'https://openalex.org/W2035718450', 'https://openalex.org/W2012988685', 'https://openalex.org/W1969576545', 'https://openalex.org/W1499113280'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2114951922', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 24}, {'year': 2012, 'cited_by_count': 21}], 'updated_date': '2025-01-04T23:44:19.194015', 'created_date': '2016-06-24'}