Publication Information

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236, 244, 283, 290, 300, 312, 348, 359, 374, 404, 407, 422, 498, 518, 524, 528, 567, 586, 615, 623, 635, 644, 656, 665, 673, 696, 709, 715, 718, 722, 732, 740, 759, 795, 798, 826, 842, 851, 855, 865, 878, 885, 904, 908, 923, 929, 946, 950, 953, 957, 968, 971, 997, 1004, 1010, 1053, 1058, 1066, 1082, 1117, 1130, 1148, 1151, 1158, 1165, 1174, 1218, 1225, 1229, 1267, 1307, 1362, 1375, 1387, 1402, 1409, 1454, 1470, 1535, 1552, 1587, 1600, 1655, 1666, 1676, 1719, 1730, 1769, 1791, 1799, 1807, 1834, 1838, 1842, 1846, 1863, 1870, 1877, 1884, 1891, 1913, 1930, 1938, 1946, 1968, 1972, 2056, 2096, 2101, 2201, 2216, 2258, 2270, 2287], 'United': [33, 313, 529, 760, 879, 1553, 1839], 'States': [34, 314, 530, 1554], 'Yingnan': [35, 42], 'Bai,': [36], 'Piero': [37, 80, 1993], 'Anversa': [38, 82, 2320, 2341], 'Junbo': [40, 118, 1977], 'Ge': [41, 120, 2136, 2454], 'BaiYingnan': [43], 'Bai': [44, 2440], 'From': [45, 83, 121], 'Department': [47, 85, 123], 'of': [48, 60, 65, 86, 98, 103, 124, 136, 141, 221, 228, 231, 247, 322, 358, 406, 425, 445, 486, 520, 585, 614, 626, 637, 646, 675, 717, 735, 739, 794, 797, 825, 845, 854, 887, 912, 919, 925, 931, 956, 970, 1009, 1063, 1072, 1108, 1150, 1160, 1164, 1177, 1191, 1231, 1272, 1310, 1319, 1331, 1374, 1389, 1420, 1456, 1464, 1469, 1482, 1515, 1522, 1573, 1622, 1654, 1668, 1675, 1705, 1733, 1762, 1776, 1783, 1788, 1827, 1845, 1858, 1866, 1872, 1879, 1886, 1890, 1895, 1897, 1916, 1929, 1948, 1967, 1971, 1981, 1997, 2001, 2100, 2155, 2172, 2192, 2206, 2218, 2262, 2269, 2273, 2323, 2496], 'Cardiology,': [49, 87, 125, 638, 676, 1982], 'Zhongshan': [50, 88, 126, 639, 677, 1983], 'Hospital,': [51, 71, 89, 109, 127, 147, 640, 1984, 2008], 'Fudan': [52, 90, 128, 641, 1985], 'University,': [53, 91, 129, 1986], 'Shanghai,': [54, 92, 130, 1987, 2195], '(Y.B.,': [56, 77, 94, 115, 132, 153], 'J.G.);': [57, 95, 133], 'Departments': [59, 97, 135, 2000], 'Anesthesia': [61, 99, 137, 2002], 'Medicine,': [63, 67, 101, 105, 139, 143, 1999, 2004], 'Division': [64, 102, 140, 1996], 'Cardiovascular': [66, 104, 142, 1998, 2488], 'Brigham': [68, 106, 144, 2005], "Women's": [70, 108, 146, 2007], 'Harvard': [72, 110, 148, 2009], 'Medical': [73, 111, 149, 2010], 'School,': [74, 112, 150, 2011], 'Boston,': [75, 113, 151, 2012], 'MA': [76, 114, 152, 2013], 'P.A.).': [78, 116, 154], ',': [79], 'AnversaPiero': [81], 'GeJunbo': [119], 'Originally': [155, 2525], 'published2': [156], 'Aug': [157], '2013https://doi.org/10.1161/CIRCRESAHA.113.302124Circulation': [158], 'Research.': [159, 2507], '2013;113:362–364is': [160], 'corrected': [161], 'byCorrectionDeath': [162], 'by': [163, 233, 308, 385, 721, 765, 834, 1356, 1504, 1726, 1750, 1833], 'heart': [164, 223, 1083, 1166, 1291, 1658, 2211, 2307, 2351, 2429], 'failure': [165, 2068, 2212, 2430], '(HF)': [166], 'is': [167, 318, 342, 490, 515, 581, 600, 654, 661, 803, 934, 940, 965, 994, 1044, 1145, 1412, 1428, 1525, 1642, 1659, 1662, 1711, 1723, 1927, 2490], 'terrible': [169], 'long': [170], 'agony': [171], 'that': [172, 365, 589, 800, 807, 861, 902, 944, 1047, 1056, 1114, 1269, 1377, 1391, 1413, 1591, 1646, 1660, 1936], 'does': [173], 'not': [174, 990, 1037, 1396, 1964], 'spare': [175], 'celebrities.': [176], 'Poets': [177], 'who': [178, 199, 617, 1527], 'wrote': [179], 'about': [180], 'broken': [181], 'hearts,': [182], 'from': [183, 209, 335, 538, 565, 767, 936, 1386, 1665, 1713, 2055], 'Samuel': [184], 'Taylor': [185, 219], 'Coleridge': [186], 'Robert': [188], 'Frost,': [189], 'Edgar': [190], 'Allan': [191], 'Poe,': [192], 'Pablo': [194], 'Neruda,': [195], 'Hollywood': [197], 'stars': [198], 'played': [200], 'on': [201, 574, 1534, 2103, 2280], 'stage': [203], 'or': [204, 1019, 1298, 1395, 1431, 1460, 1970, 1992], 'created': [205, 1577], 'characters': [206], 'experiencing': [207, 343], 'heartache': [208], 'Barbara': [210], 'Stanwyck': [211], 'Bing': [213], 'Crosby,': [214], 'Alfred': [215], 'Hitchcock,': [216], 'Elizabeth': [218], 'died': [220], 'chronic': [222, 1424, 2428], 'disease.': [224], 'The': [225, 377, 484, 658, 822, 1406, 1467, 1540, 1619, 2197], 'beautiful': [226], 'description': [227], 'sadness': [230], 'love': [232], 'Tagore,1': [234], 'perhaps': [235], 'greatest': [237], 'writer': [238], 'in': [239, 288, 299, 311, 347, 370, 373, 382, 389, 393, 396, 400, 403, 427, 464, 479, 501, 527, 592, 597, 605, 622, 655, 726, 777, 785, 812, 838, 847, 850, 864, 881, 1002, 1129, 1167, 1173, 1205, 1287, 1294, 1301, 1372, 1401, 1408, 1439, 1499, 1548, 1551, 1563, 1583, 1599, 1681, 1876, 1960, 2106, 2161, 2178, 2200, 2213, 2265, 2284, 2327, 2333, 2383, 2417, 2426, 2492], 'modern': [240, 593, 801], 'Indian': [241], 'literature,': [242], 'evokes': [243], 'dramatic': [245, 345, 525], 'experience': [246, 433], 'patients': [248, 306, 487, 647, 981, 1288, 1385, 1479, 1611, 2208], 'with': [249, 303, 413, 466, 472, 475, 488, 551, 561, 698, 706, 771, 873, 982, 1028, 1209, 1277, 1289, 1314, 1478, 1604, 1612, 1742, 1806, 2209, 2286, 2352], 'advanced': [250, 1064, 1613], 'HF': [251, 294, 489, 707, 920, 983, 1605, 1614, 1867, 1942], 'pulmonary': [253], 'edema:Suddenly': [254], 'wild': [256], 'waveBroke': [257], 'over': [258], 'my': [259], "heart's": [260], 'shoresAnd': [261], 'drowned': [262], 'all': [263], 'language.Rabindranath': [264], 'Tagore': [265, 275, 2018], 'was': [266, 276, 731], 'poet,': [268], 'philosopher,': [269], 'artist,': [270], 'playwright,': [271], 'composer,': [272], 'novelist.': [274], "India's": [277], 'first': [278, 710], 'Nobel': [279, 284], 'laureate;': [280], 'he': [281], 'won': [282], 'Prize': [285], 'Literature': [287], '1913.In': [289], 'past': [291, 666, 1067], '3': [292, 667], 'decades,': [293], 'has': [295, 391, 419, 533, 590, 831, 863, 921, 961, 989, 1036, 1075, 1084, 1098, 1126, 1304, 1366, 1474, 1501, 1542], 'reached': [296, 1475], 'endemic': [297], 'proportion': [298, 811], 'industrialized': [301, 875], 'world,': [302, 568, 866], '5.1': [304], 'million': [305, 431, 437, 441, 453, 462, 471], 'affected': [307], 'this': [309, 366, 371, 888, 926, 1143, 1320, 1568, 1728, 1880, 1949, 1961], 'syndrome': [310], 'alone': [315], 'where': [316, 1193, 1426], 'there': [317, 459, 1427], 'an': [319, 394, 542, 571], 'annual': [320], 'incidence': [321], '670': [323], '000': [324], 'new': [325, 1162, 1933, 2350], 'cases,': [326, 741], 'almost': [327], 'equally': [328], 'distributed': [329], 'between': [330], 'men': [331, 2158, 2175], 'women.2': [333], 'Data': [334], 'Europe': [336], 'are': [337, 460, 1171, 1312, 1354, 1900, 1963], 'similarly': [338], 'striking,3': [339], 'Asia': [341], 'increase': [346, 395, 495, 500, 837], 'critical': [349, 1571], 'risk': [350, 504], 'factors': [351, 505, 2203], 'HF,': [353, 507, 736, 1887], 'projecting': [354], 'worrisome': [356], 'perspective': [357], 'social,': [360], 'economical,': [361], 'medical': [363, 632, 1492, 1507, 1934], 'impact': [364, 573, 1533], 'disease': [367, 418, 514, 730, 749, 2048, 2105], 'will': [368, 494, 1528], 'have': [369, 438, 442, 454, 569, 903, 1135, 1435, 1530, 1615, 1685, 1937], 'continent': [372], 'forthcoming': [375], 'future.': [376, 1602], 'unexpected': [378], 'enormous': [379, 810, 1491], 'economic': [380, 823, 1497], 'growth': [381, 824, 1777], 'China,': [383, 1361, 2107, 2493], 'unmatched': [384], 'any': [386, 1418], 'other': [387, 874, 1241], 'country': [388, 827, 1536], 'Asia,': [390], 'resulted': [392], 'life': [397], 'expectancy': [398], 'major': [401, 503, 843, 856, 1532, 1824, 1905], 'changes': [402, 2416], 'lifestyle': [405], 'population.4': [408], 'However,': [409], 'Westernized': [410], 'customs': [411], 'come': [412, 1543], 'price': [415], 'cardiovascular': [417, 434, 513, 762, 839, 913, 2104], 'now': [420], 'become': [421], 'leading': [423], 'cause': [424, 734, 844, 1689], 'death': [426, 846], 'China.4': [428], 'Currently,': [429], '230': [430], 'Chinese': [432, 521, 575, 1523, 1835, 1853], 'disease;': [435], '200': [436], 'hypertension,': [439], '7': [440], 'history': [444], 'previous': [447], 'cerebral': [448], 'ischemic': [449, 1290], 'event,': [450], '2': [452, 502], 'experienced': [455], 'myocardial': [456, 1199, 1724, 2335], 'infarction.': [457], 'Moreover,': [458], '92.4': [461], 'adults': [463], 'diabetes': [467, 510, 2156, 2173], 'mellitus': [468], '148.2': [470], 'prediabetes': [473], 'mellitus,5,6': [474], 'higher': [477], 'frequency': [478], 'individuals': [480, 1447], 'aged': [481], '≥60': [482], 'years.': [483, 1466], 'number': [485, 645], '4.2': [491], 'million4': [492], 'but': [493, 628], 'rapidly,': [496], 'paralleling': [497], 'striking': [499], 'aging,': [508], 'mellitus.': [511], 'Thus,': [512], 'severely': [516, 1233], 'affecting': [517], 'health': [519, 890, 1457], 'today,': [522, 595], 'mimicking': [523], 'situation': [526], 'Europe.China': [532], 'undergone': [534], 'profound': [536], 'transformation': [537], 'rural': [540], 'urban': [543], 'lifestyle;': [544], 'overwhelmingly': [545], 'crowded': [546], 'cities,': [547], 'constructions': [548], 'occurring': [549], 'allover': [550], 'impressive': [552], 'skyscrapers': [553], 'huge': [555], 'condominium,': [556], 'stores': [558], 'restaurants': [560], 'products': [562, 1444], 'cuisine': [564], 'throughout': [566, 1147], 'had': [570], 'unquestionable': [572], 'culture': [576], 'daily': [578], 'routine.': [579], 'Shanghai': [580, 599, 723, 2189, 2214], 'typical': [583], 'example': [584], 'extraordinary': [587, 1494], 'revolution': [588], 'occurred': [591], 'China;': [594], 'walking': [596, 604], 'downtown': [598, 606], 'strikingly': [601], 'similar': [602, 781, 836], 'Manhattan.': [607], 'A': [608, 892, 1262, 1651], 'nice,': [609], 'comfortable': [610], 'feeling': [611], 'one': [613, 1928], 'authors': [616], 'lived': [618], '35': [620], 'years': [621, 815, 2217], 'upper': [624], 'eastside': [625], 'Manhattan,': [627], 'rather': [630], 'disturbing': [631], 'reality': [633], 'at': [634, 672, 1000], 'Institute': [636, 674, 1980], 'University.': [642], 'There,': [643], 'seen': [648], 'per': [649], 'day': [650], 'cardiac': [652, 1073, 1110, 1333, 1793, 1829, 2324, 2328, 2384, 2418], 'problems': [653, 1562], 'thousands.': [657], 'waiting': [659], 'room': [660], 'large': [663], 'auditorium.In': [664], 'years,': [668, 1069], 'outpatient': [669], 'office': [670], 'visits': [671], 'Hospital': [678], 'numbered': [679], '316': [680], '577,': [681], '354': [682], '194,': [683], '315': [685], '813,': [686], 'respectively.': [687], 'Among': [688], 'these': [689, 1917, 1922], 'patients,': [690, 2431], '11': [691], '245': [692], 'were': [693, 704, 1392], 'admitted': [694], 'hospital': [697], 'coronary': [699, 728, 1736, 1766], 'artery': [700, 729], 'disease,': [701, 998], '>300': [703], 'diagnosed': [705], 'time': [711, 820, 1541, 1617], 'each': [712], 'year.': [713], 'On': [714], 'basis': [716], 'data': [719, 1311], 'collected': [720], 'Investigation': [724, 2190], 'Group,7': [725], '2000,': [727], 'predominant': [733], 'comprising': [737], '55.7%': [738], 'whereas': [742], 'hypertension': [743], 'accounted': [744], '13.9%,': [746], 'rheumatic': [747], 'valve': [748], '8.9%,': [751], 'idiopathic': [753], 'dilated': [754], 'cardiomyopathy': [755], '7.5%.': [757], 'In': [758, 1236, 1672, 1883], 'States,': [761, 880, 1840], 'procedures': [763], 'increased': [764], '28%': [766], '2000': [768], '2010': [770], 'total': [773], 'cost': [774], '$312.6': [775], 'billion': [776], '2009,2': [778], 'phenomenon': [782], 'may': [783, 808, 1223, 1416, 1575, 1772, 1855], 'occur': [784], 'China.': [786, 1988, 2196], 'These': [787, 1155], 'staggering': [788], 'numbers': [789], 'portend': [790], 'dire': [792], 'outlook': [793], 'magnitude': [796], 'problem': [799, 806], 'facing,': [804], 'reach': [809], 'few': [814, 1932], 'represents': [817], 'veritable': [819], 'bomb.': [821], 'largest': [829], 'cities': [830], 'been': [832, 962, 992, 1038, 1085, 1100, 1127, 1305, 1367, 1436, 1502, 1686], 'paralleled': [833], 'diseases,': [840], 'currently': [841, 1429], 'China4': [848], 'Western': [852], 'world.2Because': [853], 'political': [857], 'economical': [859], 'role': [860], 'common': [867], 'strategies': [868], 'need': [869, 1049, 1803], 'be': [871, 896, 1576, 1593, 1649, 1748, 1909], 'developed': [872, 2283], 'countries': [876, 1860], 'particular,': [882], 'alleviate': [884], 'burden': [886], 'public': [889], 'problem.': [891], 'collective': [893], 'effort': [894], 'should': [895], 'made': [897, 1910], 'identify': [899], 'novel': [900], 'therapies': [901, 1390], 'potential': [905, 1451, 1939], 'modify': [907], 'onset': [909], 'evolution': [911], 'diseases': [914, 1422], 'worldwide.The': [915], 'improved': [916], 'clinical': [917, 1248, 1302, 1597, 1620, 1683, 1717, 1721], 'management': [918], 'extended': [922], 'lifespan': [924, 1149], 'patient': [927, 1950], 'population;': [928], 'quality': [930], 'life,': [932], 'however,': [933, 987, 1097], 'far': [935, 1680, 1712], 'optimal': [937], 'rehospitalization': [939], 'recurrent': [942], 'event': [943], 'reflects': [945], 'inability': [947], 'control': [949, 1379], 'process': [951], 'inexorable': [954], 'progression': [955], 'underlying': [958], 'disease.2': [959], 'What': [960], 'accomplished': [963], 'successfully': [964], 'delay': [967], 'effects': [969], 'multiple': [972, 1682], 'variables': [973], 'responsible': [974], 'negative': [976, 1828], 'ventricular': [977, 1279, 1283, 1814], 'remodeling,': [978, 1284], 'thereby': [979], 'enabling': [980], 'live': [985], 'longer;': [986], 'what': [988], 'yet': [991], 'done': [993], 'reverse': [996, 1941], 'restoring,': [999], 'least': [1001], 'part,': [1003], 'structural': [1005], 'functional': [1007, 1061], 'integrity': [1008], 'failing': [1011], 'heart.': [1012, 1235], 'Standard-of-care': [1013], 'management,': [1014], 'including': [1015, 1250], 'angiotensin-converting': [1016], 'enzyme': [1017], 'inhibitors': [1018], 'angiotensin': [1020], 'receptor': [1021], 'blockers,': [1022], 'β-blockers,': [1023], 'aldosterone': [1024], 'antagonists,': [1025], 'diuretics': [1027], 'dosing': [1029], 'schedule': [1031], 'tailored': [1032], 'maximal': [1034], 'benefit,': [1035], 'able': [1039], 'cure': [1041, 1417], 'HF.8': [1042], 'There': [1043], 'no': [1045, 1299, 1432], 'question': [1046], 'we': [1048], 'better': [1050], 'insights': [1051], 'into': [1052, 1707, 1790], 'fundamental': [1054, 1652], 'mechanisms': [1055, 1894], 'determine': [1057], 'anatomic': [1059, 1825], 'manifestations': [1062], 'HF.In': [1065], '20': [1068], 'our': [1070, 1538, 1888], 'understanding': [1071], 'pathophysiology': [1074], 'changed': [1076], 'dramatically.': [1077], 'For': [1078], 'nearly': [1079], 'century,': [1081], 'considered': [1086], 'postmitotic': [1088], 'organ': [1089, 1152], 'unable': [1090], 'replace': [1092], 'dying': [1093], 'cardiomyocytes.9': [1094], 'This': [1095, 1745], 'view,': [1096], 'recently': [1099], 'challenged': [1101], 'and,': [1102], 'despite': [1103], 'ongoing': [1104], 'controversy,': [1105], 'pool': [1107, 1782], 'resident': [1109, 1784], 'stem': [1111, 1211, 1243, 1328, 1334, 1363, 1414, 1442, 1472, 1581, 1589, 1624, 1697, 1701, 1754, 1874, 1898, 1924, 1955, 2308, 2325, 2353], 'cells': [1112, 1134, 1244, 1260, 1275, 1335, 1343, 1350, 1415, 1473, 1582, 1590, 1677, 1764, 1771, 1786, 1875, 1899, 2326], '(CSCs)': [1113], 'can': [1115, 1592, 1747, 1757], 'acquire': [1116], 'cardiomyocyte,': [1118], 'vascular': [1119], 'smooth': [1120, 1181], 'muscle,': [1121], 'endothelial': [1123, 1179], 'cell': [1124, 1140, 1364, 1443, 1794, 1925, 2309, 2375], 'lineages': [1125], 'identified': [1128], 'human': [1131, 1327, 1657, 2334], 'heart.10': [1132], 'Stem': [1133, 2311], 'high': [1137], 'propensity': [1138], 'division': [1141], 'property': [1144], 'maintained': [1146], 'organism.': [1154], 'concepts': [1156], 'form': [1157, 1419], 'foundation': [1159], 'paradigm': [1163, 2331], 'which': [1168, 1213, 1756, 1779], 'multipotent': [1169, 1752], 'CSCs': [1170, 1187, 1222], 'implicated': [1172], 'constant': [1175], 'turnover': [1176], 'myocytes,': [1178], 'cells,': [1180, 1183, 1212, 1254, 1257, 1625, 1633, 1641, 1698, 1702, 1755], 'muscle': [1182], 'fibroblasts.': [1185], 'Activated': [1186], 'translocate': [1188], 'areas': [1190], 'injury': [1192], 'they': [1194], 'grow': [1195], 'differentiate': [1197], 'making': [1198], 'regeneration': [1200], 'feasible': [1202], 'reality.10,11': [1203], 'Theoretically,': [1204], 'manner': [1207], 'comparable': [1208], 'hematopoietic': [1210], 'repopulate': [1214], 'completely': [1216], 'reconstitute': [1217], 'ablated': [1219], 'bone': [1220, 1252, 1273, 1339, 1348, 1631, 1635, 2373], 'marrow,': [1221], 'rebuild': [1224], 'injured': [1226], 'myocardium,': [1227], 'improving': [1228], 'function': [1230], 'diseased': [1234], 'addition': [1237], 'CSCs,': [1239, 1629], 'several': [1240], 'adult': [1242, 1580, 1623, 1656, 1753, 1873], 'offer': [1245], 'promise': [1246], 'application,': [1249], 'mononuclear': [1251, 1630], 'marrow': [1253, 1274, 1340, 1349, 1632, 2374], 'mesenchymal': [1255, 1341, 1639], 'stromal': [1256, 1342, 1640], 'CD34-positive': [1259, 1347], '(Figure).': [1261], 'recent': [1263], 'meta-analysis': [1264], 'strongly': [1265], 'supports': [1266], 'concept': [1268], 'various': [1270, 1792], 'classes': [1271], 'interfere': [1276], 'left': [1278], 'dysfunction,': [1280], 'infarct': [1281], 'size,': [1282], 'mortality': [1286], 'disease.12': [1292], 'Although': [1293], 'some': [1295, 1510], 'studies': [1296], 'little': [1297, 1430, 1616], 'improvement': [1300, 2382], 'outcome': [1303], 'observed,': [1306], 'overwhelming': [1308], 'majority': [1309], 'consistent': [1313], 'sustained': [1316], 'beneficial': [1317], 'effect': [1318], 'experimental': [1321], 'therapeutic': [1322], 'approach.Download': [1323], 'figureDownload': [1324], 'PowerPointFigure.': [1325], 'Adult': [1326, 2372], 'cells.': [1329, 1920], 'Culture': [1330], 'c-kit–positive': [1332], '(A,': [1336], 'green),': [1337], 'CD105-positive': [1338], '(B,': [1344], 'red),': [1345], '(C,': [1351], 'yellow).': [1352], 'Nuclei': [1353], 'stained': [1355], "4',6-diamidino-2-phenylindole": [1357], '(DAPI;': [1358], 'A–C,': [1359], 'blue).In': [1360], 'program': [1365], 'suspended': [1368], 'correctly': [1370], 'so': [1371], 'view': [1373], 'fact': [1376], 'inappropriate': [1378], 'regulations': [1381, 1844], 'failed': [1382], 'protect': [1384], 'implementation': [1388], 'either': [1393, 1797], 'dangerous': [1394], 'properly': [1397], 'established': [1398], 'validated': [1400], 'required': [1403], 'preclinical': [1404], 'studies.': [1405], 'fantasy': [1407], 'general': [1410], 'population': [1411], 'degenerative': [1421], 'illness': [1425], 'hope.': [1433], 'Charlatans': [1434], 'very': [1437, 1931], 'successful': [1438], 'selling': [1440], 'ineffective': [1441], 'desperate': [1446], 'searching': [1448], 'miracle': [1452], 'reacquisition': [1455], 'lost': [1458], 'suddenly': [1459], 'during': [1461, 2215], 'period': [1463], 'many': [1465], 'exploitation': [1468], 'term': [1471], 'incredible': [1476], 'levels': [1477], 'travelling': [1480], 'thousands': [1481], 'miles': [1483], 'find': [1485], 'charlatans': [1486], 'abusing': [1487], 'them': [1488], 'collecting': [1490], 'fees.The': [1493], 'social': [1495], 'progress': [1498], 'accompanied': [1503], 'remarkable': [1506], 'progress.': [1508], 'Despite': [1509, 1921], 'inevitable': [1511], 'difficulties': [1512], 'instances': [1514], 'questionable': [1516], 'scientific': [1517], 'rigor,': [1518], 'young': [1520], 'generation': [1521], 'scientists': [1524, 1574, 1857], 'emerging': [1526], 'soon': [1529], 'community.': [1539], 'highly': [1545], 'qualified': [1546], 'laboratories': [1547], 'join': [1556], 'forces': [1557], 'address': [1559], 'important': [1560], 'health-related': [1561], 'collaborative': [1565], 'effort.': [1566], 'With': [1567, 1796], 'strategy,': [1569], 'mass': [1572], 'study': [1579], 'coordinated': [1585, 1731], 'manner,': [1586], 'only': [1588], 'used': [1594, 1678], 'as': [1595, 1627, 1695], 'therapy': [1598, 1926, 2376], 'near': [1601], 'Patients': [1603], 'cannot': [1606], 'wait': [1607], 'much': [1608], 'longer': [1609], 'left.': [1618], 'application': [1621], 'such': [1626, 1694], 'autologous': [1628], 'marrow–derived': [1636], 'adipose-derived': [1638], 'disruptive': [1644], 'treatment': [1645, 1878, 2205], 'needs': [1647, 1907], 'tested.': [1650], 'advantage': [1653], 'it': [1661], 'largely': [1663], 'protected': [1664], 'development': [1667], 'primary': [1669], 'malignant': [1670], 'neoplasms.': [1671], 'addition,': [1673], 'none': [1674], 'thus': [1679], 'trials': [1684], 'reported': [1687], 'tumor': [1690], 'formation.12': [1691], 'Other': [1692], 'strategies,': [1693], 'embryonic': [1696], 'induced': [1699], 'pluripotent': [1700], 'reprogramming': [1704], 'fibroblasts': [1706], 'functionally': [1708], 'competent': [1709], 'cardiomyocytes': [1710, 1734], 'being': [1714], 'ready': [1715], 'use.Importantly,': [1718], 'ultimate': [1720], 'objective': [1722], 'regeneration;': [1725], 'definition,': [1727], 'implies': [1729], 'reconstitution': [1732], 'resistance': [1737], 'arteries': [1738], 'arterioles,': [1740], 'together': [1741], 'capillary': [1743], 'profiles.': [1744], 'goal': [1746], 'achieved': [1749], 'implementing': [1751], 'create': [1758], 'progeny': [1760], 'composed': [1761], 'parenchymal': [1763], 'vessels.': [1767], 'Alternatively,': [1768], 'delivered': [1770], 'release': [1773], 'variety': [1775], 'factors,': [1778], 'activate': [1780], 'primitive': [1785, 1919], 'capable': [1787], 'differentiating': [1789], 'lineages.': [1795], 'protocol,': [1798], 'newly': [1800], 'formed': [1801], 'structures': [1802], 'integrate': [1805], 'recipient': [1808], 'myocardium': [1809], 'contribute': [1811], 'global': [1813], 'performance,': [1815, 2419], 'possibly': [1816], 'attenuating': [1817], 'chamber': [1818], 'dilation': [1819], 'increasing': [1821], 'wall': [1822], 'thickness,': [1823], 'determinants': [1826], 'remodeling': [1830], 'HF.Investments': [1832], 'government': [1836], 'under': [1841], 'current': [1843], 'Food': [1847], 'Drug': [1849], 'Administration': [1850], 'its': [1852], 'equivalent,': [1854], 'help': [1856], 'both': [1859], 'understand': [1862], 'complex': [1864], 'pathogenesis': [1865], 'advance': [1869], 'use': [1871], 'devastating': [1881], 'syndrome.': [1882], 'context': [1885], 'knowledge': [1889], 'biology': [1892], 'action': [1896], 'relatively': [1901], 'poor': [1902], 'attempt': [1906], 'define': [1912], 'basic': [1914], 'properties': [1915], 'powerful': [1918], 'uncertainties,': [1923], 'options': [1935], 'materially': [1944], 'improve': [1945], 'prognosis': [1947], 'population.DisclosuresNone.Nonstandard': [1951], 'Abbreviations': [1952], 'AcronymsCSCcardiac': [1954], 'cellHFheart': [1956], 'failureFootnotesThe': [1957], 'opinions': [1958], 'expressed': [1959], 'article': [1962], 'necessarily': [1965], 'those': [1966], 'editors': [1969], 'American': [1973, 2038, 2057, 2271, 2520], 'Association.Correspondence': [1975], 'Ge,': [1978], 'MD,': [1979, 1995], 'E-mail': [1989, 2015], '[email': [1990, 2016], 'protected]': [1991], 'Anversa,': [1994], '02115.': [2014], 'protected]References1.': [2017], 'R.': [2019], 'Selected': [2020], 'poems.New': [2021], 'York,': [2022], 'NY:': [2023], 'Penguin': [2024], 'Group': [2025, 2191], '(USA)': [2026], 'Incorporated;': [2027], '2005:208.Google': [2028], 'Scholar2.': [2029], 'Go': [2030], 'AS,': [2031], 'Mozaffarian': [2032], 'D,': [2033, 2135, 2451], 'Roger': [2034], 'VL,': [2035], 'et': [2036, 2144], 'al;': [2037, 2145], 'Association': [2040, 2277], 'Statistics': [2041, 2045], 'Committee': [2042], 'Stroke': [2044], 'Subcommittee.': [2046], 'stroke': [2050], 'statistics–2013': [2051], 'update:': [2052, 2254], 'report': [2054, 2102, 2268], 'Association.Circulation.': [2059], '2013;': [2060, 2074, 2357], '127:e6–e245.LinkGoogle': [2061], 'Scholar3.': [2062], 'Guha': [2063], 'K,': [2064, 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'updated_date': '2024-12-14T04:39:28.793981', 'created_date': '2016-06-24'}