Activity of IPI-504, a Novel Heat-Shock Protein 90 Inhibitor, in Patients With Molecularly Defined Non–Small-Cell Lung Cancer

Name: Work Video:
Duration: 3 min 30 s
Lecia V. Sequist; Scott Gettinger; Neil Senzer; Renato Martins; Pasi A. Jänne; Rogerio Lilenbaum; Jhanelle E. Gray; A. John Iafrate; Ryohei Katayama; Nafeeza Hafeez; Jennifer Sweeney; John R. Walker; Christian Fritz; Robert W. Ross; David Grayzel; Jeffrey A. Engelman; Darrell R. Borger; Guillermo Paez; Ronald B. Natale
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Harvard Medical School; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston; Infinity Pharmaceuticals, Inc, Cambridge, MA; Yale University School of Medicine and Yale Cancer Center, New Haven, CT; Mary Crowley Cancer Research Center, Dallas, TX; University of Washington, Seattle, WA; Mt Sinai Cancer Center, Miami Beach; Moffitt Cancer Center, Tampa, FL; and Cedars-Sinai Medical Center, Los Angeles, CA.', 'Harvard Medical School, Massachusetts General Hospital Cancer Center, 55 Fruit St, POB 212, Boston, MA, 02114;', 'Mary Crowley Cancer Research Center, Dallas, TX;', 'Mt Sinai Cancer Center, Miami Beach; Moffitt Cancer Center, Tampa, FL; and', 'University of Washington, Seattle, WA;', 'Yale University School of Medicine and Yale Cancer Center, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'From the Massachusetts General Hospital Cancer Center; Harvard Medical School; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston; Infinity Pharmaceuticals, Inc, Cambridge, MA; 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Harvard Medical School; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston; Infinity Pharmaceuticals, Inc, Cambridge, MA; Yale University School of Medicine and Yale Cancer Center, New Haven, CT; Mary Crowley Cancer Research Center, Dallas, TX; University of Washington, Seattle, WA; Mt Sinai Cancer Center, Miami Beach; Moffitt Cancer Center, Tampa, FL; and Cedars-Sinai Medical Center, Los Angeles, CA.', 'institution_ids': ['https://openalex.org/I4210108457', 'https://openalex.org/I3019308854', 'https://openalex.org/I4210117453', 'https://openalex.org/I1282927834', 'https://openalex.org/I2802730090', 'https://openalex.org/I4210127473']}, {'raw_affiliation_string': 'Yale University School of Medicine and Yale Cancer Center, New Haven, CT;', 'institution_ids': ['https://openalex.org/I2802730090', 'https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Mary Crowley Cancer Research Center, Dallas, TX;', 'institution_ids': ['https://openalex.org/I4210087725']}, {'raw_affiliation_string': 'University of Washington, Seattle, WA;', 'institution_ids': ['https://openalex.org/I201448701']}, {'raw_affiliation_string': 'Harvard Medical School, Massachusetts General Hospital Cancer Center, 55 Fruit St, POB 212, Boston, MA, 02114;', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112877054', 'display_name': 'Jennifer Sweeney', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210108457', 'display_name': 'Infinity Pharmaceuticals (United States)', 'ror': 'https://ror.org/01sfsq511', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108457']}, {'id': 'https://openalex.org/I3019308854', 'display_name': 'Moffitt Cancer Center', 'ror': 'https://ror.org/01xf75524', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019308854']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I1282927834', 'display_name': 'Cedars-Sinai Medical Center', 'ror': 'https://ror.org/02pammg90', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1282927834']}, {'id': 'https://openalex.org/I2802730090', 'display_name': 'Yale Cancer Center', 'ror': 'https://ror.org/03j7sze86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I2802730090', 'https://openalex.org/I4210117499', 'https://openalex.org/I4210165192']}, {'id': 'https://openalex.org/I4210127473', 'display_name': 'Cancer Research Center', 'ror': 'https://ror.org/03fbwjm33', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210127473']}, {'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}, {'id': 'https://openalex.org/I4210087725', 'display_name': 'Mary Crowley Cancer Research Center', 'ror': 'https://ror.org/002ksg449', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210087725']}, {'id': 'https://openalex.org/I201448701', 'display_name': 'University of Washington', 'ror': 'https://ror.org/00cvxb145', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I201448701']}, {'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jennifer Sweeney', 'raw_affiliation_strings': ['Cedars-Sinai Medical Center, Los Angeles, CA.', 'From the Massachusetts General Hospital Cancer Center; 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Yale University School of Medicine and Yale Cancer Center, New Haven, CT; Mary Crowley Cancer Research Center, Dallas, TX; University of Washington, Seattle, WA; Mt Sinai Cancer Center, Miami Beach; Moffitt Cancer Center, Tampa, FL; and Cedars-Sinai Medical Center, Los Angeles, CA.', 'institution_ids': ['https://openalex.org/I4210108457', 'https://openalex.org/I3019308854', 'https://openalex.org/I4210117453', 'https://openalex.org/I1282927834', 'https://openalex.org/I2802730090', 'https://openalex.org/I4210127473']}, {'raw_affiliation_string': 'Yale University School of Medicine and Yale Cancer Center, New Haven, CT;', 'institution_ids': ['https://openalex.org/I2802730090', 'https://openalex.org/I32971472']}, {'raw_affiliation_string': 'Mary Crowley Cancer Research Center, Dallas, TX;', 'institution_ids': ['https://openalex.org/I4210087725']}, {'raw_affiliation_string': 'University of Washington, Seattle, WA;', 'institution_ids': ['https://openalex.org/I201448701']}, {'raw_affiliation_string': 'Mt Sinai Cancer Center, Miami Beach; 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