Title: Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta-analysis of studies performed in a clinical setting
Abstract: British Journal of DermatologyVolume 159, Issue 3 p. 669-676 Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta-analysis of studies performed in a clinical setting M.E. Vestergaard, M.E. Vestergaard The Sydney Melanoma Diagnostic Centre and The Department of Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaSearch for more papers by this authorP. Macaskill, P. Macaskill The School of Public Health, University of Sydney, NSW 2006, AustraliaSearch for more papers by this authorP.E. Holt, P.E. Holt NSW Melanoma Network, 349 Pacific Hwy, North Sydney, NSW 2060, Australia Central Clinical School, The Faculty of Medicine, University of Sydney, NSW 2006, AustraliaSearch for more papers by this authorS.W. Menzies, S.W. Menzies The Sydney Melanoma Diagnostic Centre and The Department of Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia Central Clinical School, The Faculty of Medicine, University of Sydney, NSW 2006, AustraliaSearch for more papers by this author M.E. Vestergaard, M.E. Vestergaard The Sydney Melanoma Diagnostic Centre and The Department of Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, AustraliaSearch for more papers by this authorP. Macaskill, P. Macaskill The School of Public Health, University of Sydney, NSW 2006, AustraliaSearch for more papers by this authorP.E. Holt, P.E. Holt NSW Melanoma Network, 349 Pacific Hwy, North Sydney, NSW 2060, Australia Central Clinical School, The Faculty of Medicine, University of Sydney, NSW 2006, AustraliaSearch for more papers by this authorS.W. Menzies, S.W. Menzies The Sydney Melanoma Diagnostic Centre and The Department of Dermatology, Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia Central Clinical School, The Faculty of Medicine, University of Sydney, NSW 2006, AustraliaSearch for more papers by this author First published: 21 August 2008 https://doi.org/10.1111/j.1365-2133.2008.08713.xCitations: 235 S.W. Menzies.E-mail: [email protected] Conflicts of interestNone declared. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Summary Background Dermoscopy is a noninvasive technique that enables the clinician to perform direct microscopic examination of diagnostic features, not seen by the naked eye, in pigmented skin lesions. Diagnostic accuracy of dermoscopy has previously been assessed in meta-analyses including studies performed in experimental and clinical settings. Objectives To assess the diagnostic accuracy of dermoscopy for the diagnosis of melanoma compared with naked eye examination by performing a meta-analysis exclusively on studies performed in a clinical setting. Methods We searched for publications from 1987 to January 2008 and found nine eligible studies. The selected studies compare diagnostic accuracy of dermoscopy with naked eye examination using a valid reference test on consecutive patients with a defined clinical presentation, performed in a clinical setting. Hierarchical summary receiver operator curve analysis was used to estimate the relative diagnostic accuracy for clinical examination with, and without, the use of dermoscopy. Results We found the relative diagnostic odds ratio for melanoma, for dermoscopy compared with naked eye examination, to be 15·6 [95% confidence interval (CI) 2·9–83·7, P = 0·016]; removal of two outlier studies changed this to 9·0 (95% CI 1·5–54·6, P = 0·03). Conclusions Dermoscopy is more accurate than naked eye examination for the diagnosis of cutaneous melanoma in suspicious skin lesions when performed in the clinical setting. Citing Literature Volume159, Issue3September 2008Pages 669-676 RelatedInformation
Publication Year: 2008
Publication Date: 2008-06-01
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 765
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