Publication Information

{'id': 'https://openalex.org/W2113569308', 'doi': 'https://doi.org/10.1200/jco.2009.24.1281', 'title': 'Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconazole Therapy', 'display_name': 'Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconazole Therapy', 'publication_year': 2010, 'publication_date': '2010-02-17', 'ids': {'openalex': 'https://openalex.org/W2113569308', 'doi': 'https://doi.org/10.1200/jco.2009.24.1281', 'mag': '2113569308', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20159824', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2849769'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1200/jco.2009.24.1281', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S15137598', 'display_name': 'Journal of Clinical Oncology', 'issn_l': '0732-183X', 'issn': ['0732-183X', '1527-7755'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc2849769?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5012804612', 'display_name': 'Charles J. Ryan', 'orcid': 'https://orcid.org/0000-0002-2081-3557'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Charles J. Ryan', 'raw_affiliation_strings': ['From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.'], 'affiliations': [{'raw_affiliation_string': 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'institution_ids': ['https://openalex.org/I142947616', 'https://openalex.org/I4210117453', 'https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105370289', 'display_name': 'Matthew R. Smith', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I4210167126', 'display_name': 'UCSF Helen Diller Family Comprehensive Cancer Center', 'ror': 'https://ror.org/05yndxy10', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I180670191', 'https://openalex.org/I4210110664', 'https://openalex.org/I4210167126']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Matthew R. Smith', 'raw_affiliation_strings': ['Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'Urologic Oncology Program, University of California, San Francisco;'], 'affiliations': [{'raw_affiliation_string': 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'institution_ids': ['https://openalex.org/I142947616', 'https://openalex.org/I4210117453', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Urologic Oncology Program, University of California, San Francisco;', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073970384', 'display_name': 'Lawrence Fong', 'orcid': 'https://orcid.org/0000-0002-6428-428X'}, 'institutions': [{'id': 'https://openalex.org/I4210167126', 'display_name': 'UCSF Helen Diller Family Comprehensive Cancer Center', 'ror': 'https://ror.org/05yndxy10', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I180670191', 'https://openalex.org/I4210110664', 'https://openalex.org/I4210167126']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Lawrence Fong', 'raw_affiliation_strings': ['Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'Urologic Oncology Program, University of California, San Francisco;'], 'affiliations': [{'raw_affiliation_string': 'Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Urologic Oncology Program, University of California, San Francisco;', 'institution_ids': ['https://openalex.org/I180670191']}, {'raw_affiliation_string': 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'institution_ids': ['https://openalex.org/I142947616', 'https://openalex.org/I4210117453', 'https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050435057', 'display_name': 'Jonathan E. Rosenberg', 'orcid': 'https://orcid.org/0000-0003-2637-4249'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}, {'id': 'https://openalex.org/I4210167126', 'display_name': 'UCSF Helen Diller Family Comprehensive Cancer Center', 'ror': 'https://ror.org/05yndxy10', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I180670191', 'https://openalex.org/I4210110664', 'https://openalex.org/I4210167126']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan E. Rosenberg', 'raw_affiliation_strings': ['Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'Urologic Oncology Program, University of California, San Francisco;'], 'affiliations': [{'raw_affiliation_string': 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'institution_ids': ['https://openalex.org/I142947616', 'https://openalex.org/I4210117453', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Urologic Oncology Program, University of California, San Francisco;', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056766924', 'display_name': 'Philip W. Kantoff', 'orcid': 'https://orcid.org/0000-0001-7275-0597'}, 'institutions': [{'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}, {'id': 'https://openalex.org/I4210167126', 'display_name': 'UCSF Helen Diller Family Comprehensive Cancer Center', 'ror': 'https://ror.org/05yndxy10', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I180670191', 'https://openalex.org/I4210110664', 'https://openalex.org/I4210167126']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Philip Kantoff', 'raw_affiliation_strings': ['Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'Urologic Oncology Program, University of California, San Francisco;'], 'affiliations': [{'raw_affiliation_string': 'From the Urologic Oncology Program, University of California, San Francisco; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; Cougar Biotechnology, Los Angeles, CA; Massachusetts General Hospital; Dana-Farber Cancer Institute, Lank Center for Genitourinary Oncology, Boston, MA; and Institute of Cancer Research, Drug Metabolism and Pharmacokinetics Team, Belmont, Sutton, United Kingdom.', 'institution_ids': ['https://openalex.org/I142947616', 'https://openalex.org/I4210117453', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'institution_ids': ['https://openalex.org/I4210167126', 'https://openalex.org/I180670191']}, {'raw_affiliation_string': 'Urologic Oncology Program, University of California, San Francisco;', 'institution_ids': ['https://openalex.org/I180670191']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058014829', 'display_name': 'Florence I. Raynaud', 'orcid': 'https://orcid.org/0000-0003-0957-6279'}, 'institutions': [{'id': 'https://openalex.org/I4210117453', 'display_name': 'Dana-Farber Cancer Institute', 'ror': 'https://ror.org/02jzgtq86', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117453']}, {'id': 'https://openalex.org/I4210167126', 'display_name': 'UCSF Helen Diller Family Comprehensive Cancer Center', 'ror': 'https://ror.org/05yndxy10', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I180670191', 'https://openalex.org/I4210110664', 'https://openalex.org/I4210167126']}, {'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I180670191']}, {'id': 'https://openalex.org/I142947616', 'display_name': 'Institute of Cancer Research', 'ror': 'https://ror.org/043jzw605', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I124357947', 'https://openalex.org/I142947616']}], 'countries': ['GB', 'US'], 'is_corresponding': False, 'raw_author_name': 'Florence Raynaud', 'raw_affiliation_strings': ['Associate Professor of Clinical Medicine, Helen Diller Family Compre-hensive Cancer Center, University of California, San Francisco, 1600 Divisad-ero St, San Francisco, CA 94115;', 'Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco;', 'From the Urologic Oncology Program, University of California, San Francisco; 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