Title: Dyslipidaemia in patients with chronic kidney disease and treatment
Abstract: Introduction Treatment of dyslipidaemia complicated by chronic kidney disease is important for preventing the development of cardiovascular disease. The pathogenesis of dyslipidaemia associated with chronic kidney disease varies depending on urinary protein level and the stage of chronic kidney disease. Hypocholesterolaemia is associated with malnutrition and inflammation and also leads to the poor prognosis of dialysis patients. Statins are expected to prevent the development of cardiovascular disease in non-dialysis chronic kidney disease patients; however, there is no evidence of the efficacy of statins in preventing the development of cardiovascular disease in dialysis patients. Treatment strategies for dyslipidaemia in chronic kidney disease patients mainly include lifestyle changes, dietary therapies and medications such as statins; care should be taken with regard to the side effects of medicines. The aim of this article is to discuss dyslipidaemia in patients with chronic kidney disease. Conclusion Patients who showed abnormal findings in the lipid test should be treated by considering not only their test results but also their general condition including nutritional condition, medical history and complications. Personalised treatment of each patient, rather than across-the-board treatment, is necessary.