Publication Information

{'id': 'https://openalex.org/W2112203633', 'doi': 'https://doi.org/10.1128/jvi.01921-10', 'title': 'Cell-Associated Viral Burden Provides Evidence of Ongoing Viral Replication in Aviremic HIV-2-Infected Patients', 'display_name': 'Cell-Associated Viral Burden Provides Evidence of Ongoing Viral Replication in Aviremic HIV-2-Infected Patients', 'publication_year': 2010, 'publication_date': '2010-12-16', 'ids': {'openalex': 'https://openalex.org/W2112203633', 'doi': 'https://doi.org/10.1128/jvi.01921-10', 'mag': '2112203633', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21159859', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3067805'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/jvi.01921-10', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://repositorio.ul.pt/bitstream/10451/11304/1/Cell_associated_viral.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055878897', 'display_name': 'Rui S. Soares', 'orcid': 'https://orcid.org/0000-0001-6573-5292'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Rui S. Soares', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031101116', 'display_name': 'Rita Tendeiro', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Rita Tendeiro', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041252219', 'display_name': 'Russell B. Foxall', 'orcid': 'https://orcid.org/0000-0001-9821-0708'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Russell B. Foxall', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018724933', 'display_name': 'António P. Baptista', 'orcid': 'https://orcid.org/0000-0001-8182-8982'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'António P. Baptista', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005204111', 'display_name': 'Rita Cavaleiro', 'orcid': 'https://orcid.org/0000-0002-3949-6088'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Rita Cavaleiro', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006716772', 'display_name': 'Perpétua Gómes', 'orcid': 'https://orcid.org/0000-0003-3271-8255'}, 'institutions': [{'id': 'https://openalex.org/I4210106487', 'display_name': 'Hospital de Egas Moniz', 'ror': 'https://ror.org/012habm93', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210106487']}, {'id': 'https://openalex.org/I3132158377', 'display_name': 'Escola Superior de Saúde Egas Moniz', 'ror': 'https://ror.org/01prbq409', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I3132158377']}, {'id': 'https://openalex.org/I4210166638', 'display_name': 'Instituto de Investigação Científica Tropical', 'ror': 'https://ror.org/007qsya74', 'country_code': 'PT', 'type': 'government', 'lineage': ['https://openalex.org/I4210146676', 'https://openalex.org/I4210166638']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Perpétua Gomes', 'raw_affiliation_strings': ['CMDT, Instituto Superior de Higiene e Medicina Tropical, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal', 'Instituto Superior de Saúde Egas Moniz, Quinta da Granja, Monte de Caparica, 2829-511 Caparica, Portugal', 'Laboratório de Biologia Molecular, Serviço de Medicina Transfusional, Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Laboratório de Biologia Molecular, Serviço de Medicina Transfusional, Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210106487']}, {'raw_affiliation_string': 'Instituto Superior de Saúde Egas Moniz, Quinta da Granja, Monte de Caparica, 2829-511 Caparica, Portugal', 'institution_ids': ['https://openalex.org/I3132158377']}, {'raw_affiliation_string': 'CMDT, Instituto Superior de Higiene e Medicina Tropical, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210166638']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040598007', 'display_name': 'Ricardo Camacho', 'orcid': 'https://orcid.org/0000-0002-9129-3237'}, 'institutions': [{'id': 'https://openalex.org/I4210106487', 'display_name': 'Hospital de Egas Moniz', 'ror': 'https://ror.org/012habm93', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210106487']}, {'id': 'https://openalex.org/I4210166638', 'display_name': 'Instituto de Investigação Científica Tropical', 'ror': 'https://ror.org/007qsya74', 'country_code': 'PT', 'type': 'government', 'lineage': ['https://openalex.org/I4210146676', 'https://openalex.org/I4210166638']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Ricardo Camacho', 'raw_affiliation_strings': ['CMDT, Instituto Superior de Higiene e Medicina Tropical, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal', 'Laboratório de Biologia Molecular, Serviço de Medicina Transfusional, Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Laboratório de Biologia Molecular, Serviço de Medicina Transfusional, Hospital Egas Moniz, Rua da Junqueira, 126, 1349-019 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210106487']}, {'raw_affiliation_string': 'CMDT, Instituto Superior de Higiene e Medicina Tropical, Rua da Junqueira, 96, 1349-008 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210166638']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068665734', 'display_name': 'Emília Valadas', 'orcid': 'https://orcid.org/0000-0001-5213-1473'}, 'institutions': [{'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Emília Valadas', 'raw_affiliation_strings': ['Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210149283', 'https://openalex.org/I4210114390']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038894930', 'display_name': 'Manuela Doroana', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Manuela Doroana', 'raw_affiliation_strings': ['Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210149283', 'https://openalex.org/I4210114390']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111820723', 'display_name': 'Margarida Lucas', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Margarida Lucas', 'raw_affiliation_strings': ['Clínica Universitária de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Clínica Universitária de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210149283', 'https://openalex.org/I4210114390']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027093678', 'display_name': 'Francisco Antunes', 'orcid': 'https://orcid.org/0000-0001-7932-1154'}, 'institutions': [{'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Francisco Antunes', 'raw_affiliation_strings': ['Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': 'Clínica Universitária de Doenças Infecciosas e Parasitárias, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210149283', 'https://openalex.org/I4210114390']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084277682', 'display_name': 'Rui M. M. Victorino', 'orcid': 'https://orcid.org/0000-0001-7567-1704'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}, {'id': 'https://openalex.org/I4210149283', 'display_name': 'Hospital de Santa Maria', 'ror': 'https://ror.org/05bz1tw26', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210149283']}, {'id': 'https://openalex.org/I4210114390', 'display_name': 'Centro Hospitalar Lisboa Norte', 'ror': 'https://ror.org/020sr6z07', 'country_code': 'PT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114390']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Rui M. M. Victorino', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'Clínica Universitária de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}, {'raw_affiliation_string': 'Clínica Universitária de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I4210149283', 'https://openalex.org/I4210114390']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051793876', 'display_name': 'Ana E. Sousa', 'orcid': 'https://orcid.org/0000-0002-4618-9799'}, 'institutions': [{'id': 'https://openalex.org/I141596103', 'display_name': 'University of Lisbon', 'ror': 'https://ror.org/01c27hj86', 'country_code': 'PT', 'type': 'education', 'lineage': ['https://openalex.org/I141596103']}], 'countries': ['PT'], 'is_corresponding': False, 'raw_author_name': 'Ana E. Sousa', 'raw_affiliation_strings': ['1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal'], 'affiliations': [{'raw_affiliation_string': '1Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal', 'institution_ids': ['https://openalex.org/I141596103']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 2.223, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 51, 'citation_normalized_percentile': {'value': 0.858221, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '85', 'issue': '5', 'first_page': '2429', 'last_page': '2438'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10082', 'display_name': 'HIV/AIDS Research and Interventions', 'score': 0.993, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/viremia', 'display_name': 'Viremia', 'score': 0.94595623}], 'concepts': [{'id': 'https://openalex.org/C2776185481', 'wikidata': 'https://www.wikidata.org/wiki/Q1425304', 'display_name': 'Viremia', 'level': 3, 'score': 0.94595623}, {'id': 'https://openalex.org/C140704245', 'wikidata': 'https://www.wikidata.org/wiki/Q3933202', 'display_name': 'Viral replication', 'level': 3, 'score': 0.7366978}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.6917418}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.63697827}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.6091001}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.55326885}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.507594}, {'id': 'https://openalex.org/C156719811', 'wikidata': 'https://www.wikidata.org/wiki/Q28774', 'display_name': 'Reverse transcriptase', 'level': 4, 'score': 0.45891392}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.45717576}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.44886976}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.43024415}, {'id': 'https://openalex.org/C2779690655', 'wikidata': 'https://www.wikidata.org/wiki/Q374232', 'display_name': 'Lentivirus', 'level': 4, 'score': 0.4269384}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.35356617}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.30335075}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.19411287}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.16378814}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.09590903}], 'mesh': [{'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D015498', 'descriptor_name': 'HIV-2', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D019562', 'descriptor_name': 'Viral Load', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014766', 'descriptor_name': 'Viremia', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': True}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015331', 'descriptor_name': 'Cohort Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015498', 'descriptor_name': 'HIV-2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015498', 'descriptor_name': 'HIV-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014766', 'descriptor_name': 'Viremia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D014766', 'descriptor_name': 'Viremia', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D014766', 'descriptor_name': 'Viremia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1128/jvi.01921-10', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10451/11304', 'pdf_url': 'https://repositorio.ul.pt/bitstream/10451/11304/1/Cell_associated_viral.pdf', 'source': {'id': 'https://openalex.org/S4306402433', 'display_name': 'Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3067805', 'pdf_url': 'https://europepmc.org/articles/pmc3067805?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067805', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21159859', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://hdl.handle.net/10451/11304', 'pdf_url': 'https://repositorio.ul.pt/bitstream/10451/11304/1/Cell_associated_viral.pdf', 'source': {'id': 'https://openalex.org/S4306402433', 'display_name': 'Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.79, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 64, 'referenced_works': ['https://openalex.org/W1533292031', 'https://openalex.org/W1593830054', 'https://openalex.org/W170094209', 'https://openalex.org/W1753464271', 'https://openalex.org/W1764027468', 'https://openalex.org/W1837528589', 'https://openalex.org/W1874436941', 'https://openalex.org/W1966463652', 'https://openalex.org/W1967281938', 'https://openalex.org/W1970640392', 'https://openalex.org/W1978217124', 'https://openalex.org/W1985591364', 'https://openalex.org/W1995955039', 'https://openalex.org/W1998057529', 'https://openalex.org/W2006266639', 'https://openalex.org/W2007498035', 'https://openalex.org/W2007607803', 'https://openalex.org/W2010697642', 'https://openalex.org/W2023513435', 'https://openalex.org/W2025481552', 'https://openalex.org/W2029713308', 'https://openalex.org/W2030844138', 'https://openalex.org/W2037716012', 'https://openalex.org/W2039299595', 'https://openalex.org/W2039975091', 'https://openalex.org/W2044816496', 'https://openalex.org/W2046487462', 'https://openalex.org/W2047114008', 'https://openalex.org/W2053711547', 'https://openalex.org/W2056360005', 'https://openalex.org/W2060829964', 'https://openalex.org/W2066184048', 'https://openalex.org/W2070588546', 'https://openalex.org/W2077563405', 'https://openalex.org/W2077771443', 'https://openalex.org/W2083281261', 'https://openalex.org/W2084175877', 'https://openalex.org/W2085463716', 'https://openalex.org/W2098304796', 'https://openalex.org/W2101610242', 'https://openalex.org/W2107820189', 'https://openalex.org/W2111524442', 'https://openalex.org/W2118330511', 'https://openalex.org/W2119327257', 'https://openalex.org/W2119458733', 'https://openalex.org/W2119829976', 'https://openalex.org/W2119974226', 'https://openalex.org/W2121358171', 'https://openalex.org/W2122057458', 'https://openalex.org/W2122386884', 'https://openalex.org/W2128031350', 'https://openalex.org/W2128620327', 'https://openalex.org/W2129579037', 'https://openalex.org/W2131464630', 'https://openalex.org/W2132782992', 'https://openalex.org/W2144294734', 'https://openalex.org/W2158676450', 'https://openalex.org/W2159236259', 'https://openalex.org/W2162703468', 'https://openalex.org/W2164641431', 'https://openalex.org/W2167383584', 'https://openalex.org/W2168876922', 'https://openalex.org/W2914058108', 'https://openalex.org/W617294916'], 'related_works': ['https://openalex.org/W4249966514', 'https://openalex.org/W4236946429', 'https://openalex.org/W2183070931', 'https://openalex.org/W2155166599', 'https://openalex.org/W2151822474', 'https://openalex.org/W2101501163', 'https://openalex.org/W2091660763', 'https://openalex.org/W2060636772', 'https://openalex.org/W2047953065', 'https://openalex.org/W1975893429'], 'abstract_inverted_index': {'Viremia': [0], 'is': [1, 67, 105], 'significantly': [2, 91], 'lower': [3, 92], 'in': [4, 7, 69, 94, 107, 178], 'HIV-2': [5, 208], 'than': [6], 'HIV-1': [8], 'infection,': [9], 'irrespective': [10, 139], 'of': [11, 28, 101, 117, 140, 148, 173, 187, 204], 'disease': [12], 'stage.': [13], 'Nevertheless,': [14], 'the': [15, 74, 99, 146, 183, 196, 202], 'comparable': [16], 'proviral': [17], 'DNA': [18], 'burdens': [19], 'observed': [20, 89, 163], 'for': [21, 52, 198, 207], 'these': [22, 108, 165], 'two': [23], 'infections': [24], 'indicate': [25], 'similar': [26, 58], 'numbers': [27], 'infected': [29], 'cells.': [30], 'Here': [31], 'we': [32, 162, 169], 'investigated': [33], 'this': [34], 'apparent': [35], 'paradox': [36], 'by': [37], 'assessing': [38], 'cell-associated': [39, 191], 'viral': [40, 65, 137, 176, 192], 'replication.': [41], 'We': [42], 'found': [43], 'that': [44, 63, 98, 161], 'untreated': [45, 70], 'HIV-1-positive': [46], '(HIV-1(+))': [47], 'and': [48, 119, 124, 155, 190, 194, 201], 'HIV-2(+)': [49, 71, 95, 133, 179], 'individuals,': [50], 'matched': [51], 'CD4': [53, 123, 157], 'T': [54, 126, 158], 'cell': [55, 127, 159], 'depletion,': [56], 'exhibited': [57], 'gag': [59, 118], 'mRNA': [60, 86], 'levels,': [61], 'indicating': [62], 'significant': [64, 174], 'transcription': [66], 'occurring': [68], 'patients,': [72, 96, 180], 'despite': [73], 'reduced': [75], 'viremia': [76], '(undetectable': [77], 'to': [78, 145], '2.6': [79], '×': [80], '10(4)': [81], 'RNA': [82], 'copies/ml).': [83], 'However,': [84], 'tat': [85, 120], 'transcripts': [87, 121], 'were': [88], 'at': [90], 'levels': [93], 'suggesting': [97], 'rate': [100], 'de': [102], 'novo': [103], 'infection': [104], 'decreased': [106], 'patients.': [109], 'Our': [110], 'data': [111], 'also': [112], 'reveal': [113], 'a': [114], 'direct': [115], 'relationship': [116], 'with': [122, 164], 'CD8': [125], 'activation,': [128, 154], 'respectively.': [129], 'Antiretroviral': [130], 'therapy': [131], '(ART)-treated': [132], 'patients': [134], 'showed': [135], 'persistent': [136, 152], 'replication,': [138], 'plasma': [141, 188], 'viremia,': [142], 'possibly': [143], 'contributing': [144], 'emergence': [147], 'drug': [149], 'resistance': [150], 'mutations,': [151], 'hyperimmune': [153], 'poor': [156], 'recovery': [160], 'individuals.': [166], 'In': [167], 'conclusion,': [168], 'provide': [170], 'here': [171], 'evidence': [172], 'ongoing': [175], 'replication': [177], 'further': [181], 'emphasizing': [182], 'dichotomy': [184], 'between': [185], 'amount': [186], 'virus': [189], 'burden': [193], 'stressing': [195], 'need': [197], 'antiretroviral': [199], 'trials': [200], 'definition': [203], 'therapeutic': [205], 'guidelines': [206], 'infection.': [209]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2112203633', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-10T16:21:07.744884', 'created_date': '2016-06-24'}