Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2112179844', 'doi': 'https://doi.org/10.1084/jem.189.7.1093', 'title': 'A Human Histocompatibility Leukocyte Antigen (HLA)-G–specific Receptor Expressed on All Natural Killer Cells', 'display_name': 'A Human Histocompatibility Leukocyte Antigen (HLA)-G–specific Receptor Expressed on All Natural Killer Cells', 'publication_year': 1999, 'publication_date': '1999-04-05', 'ids': {'openalex': 'https://openalex.org/W2112179844', 'doi': 'https://doi.org/10.1084/jem.189.7.1093', 'mag': '2112179844', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10190900', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2193010'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.189.7.1093', 'pdf_url': 'https://rupress.org/jem/article-pdf/189/7/1093/1120405/98-1723.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://rupress.org/jem/article-pdf/189/7/1093/1120405/98-1723.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080329326', 'display_name': 'Sumati Rajagopalan', 'orcid': 'https://orcid.org/0009-0002-7690-2767'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sumati Rajagopalan', 'raw_affiliation_strings': ['From the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852'], 'affiliations': [{'raw_affiliation_string': 'From the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087340494', 'display_name': 'Eric O. Long', 'orcid': 'https://orcid.org/0000-0002-7793-3728'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eric O. Long', 'raw_affiliation_strings': ['From the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852'], 'affiliations': [{'raw_affiliation_string': 'From the Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852', 'institution_ids': ['https://openalex.org/I4210134534', 'https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 11.243, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 711, 'citation_normalized_percentile': {'value': 0.999848, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '189', 'issue': '7', 'first_page': '1093', 'last_page': '1100'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11510', 'display_name': 'Reproductive System and Pregnancy', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9325, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hla-g', 'display_name': 'HLA-G', 'score': 0.7838835}, {'id': 'https://openalex.org/keywords/trophoblast', 'display_name': 'Trophoblast', 'score': 0.5227404}, {'id': 'https://openalex.org/keywords/lymphokine-activated-killer-cell', 'display_name': 'Lymphokine-activated killer cell', 'score': 0.49750522}, {'id': 'https://openalex.org/keywords/janus-kinase-3', 'display_name': 'Janus kinase 3', 'score': 0.44242522}], 'concepts': [{'id': 'https://openalex.org/C2780027760', 'wikidata': 'https://www.wikidata.org/wiki/Q3124896', 'display_name': 'HLA-G', 'level': 4, 'score': 0.7838835}, {'id': 'https://openalex.org/C188280979', 'wikidata': 'https://www.wikidata.org/wiki/Q911125', 'display_name': 'Human leukocyte antigen', 'level': 3, 'score': 0.67907286}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6757241}, {'id': 'https://openalex.org/C207936829', 'wikidata': 'https://www.wikidata.org/wiki/Q423163', 'display_name': 'Major histocompatibility complex', 'level': 3, 'score': 0.5889189}, {'id': 'https://openalex.org/C2777495146', 'wikidata': 'https://www.wikidata.org/wiki/Q1889778', 'display_name': 'Trophoblast', 'level': 5, 'score': 0.5227404}, {'id': 'https://openalex.org/C2778102761', 'wikidata': 'https://www.wikidata.org/wiki/Q332181', 'display_name': 'Natural killer cell', 'level': 4, 'score': 0.5168541}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5039484}, {'id': 'https://openalex.org/C28651165', 'wikidata': 'https://www.wikidata.org/wiki/Q4259786', 'display_name': 'Lymphokine-activated killer cell', 'level': 5, 'score': 0.49750522}, {'id': 'https://openalex.org/C139563560', 'wikidata': 'https://www.wikidata.org/wiki/Q224930', 'display_name': 'Natural killer T cell', 'level': 4, 'score': 0.45561868}, {'id': 'https://openalex.org/C183315844', 'wikidata': 'https://www.wikidata.org/wiki/Q6155969', 'display_name': 'Janus kinase 3', 'level': 5, 'score': 0.44242522}, {'id': 'https://openalex.org/C129374314', 'wikidata': 'https://www.wikidata.org/wiki/Q909381', 'display_name': 'Interleukin 21', 'level': 4, 'score': 0.42794576}, {'id': 'https://openalex.org/C170627219', 'wikidata': 'https://www.wikidata.org/wiki/Q13218497', 'display_name': 'MHC class I', 'level': 4, 'score': 0.41768432}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.41655767}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.4134811}, {'id': 'https://openalex.org/C149532602', 'wikidata': 'https://www.wikidata.org/wiki/Q2409681', 'display_name': 'Interleukin 12', 'level': 4, 'score': 0.4123245}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.38806713}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.18000245}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13646963}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.11126828}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.10223967}, {'id': 'https://openalex.org/C2776953305', 'wikidata': 'https://www.wikidata.org/wiki/Q1212935', 'display_name': 'Placenta', 'level': 4, 'score': 0.094015}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015395', 'descriptor_name': 'Histocompatibility Antigens Class I', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D014327', 'descriptor_name': 'Trophoblasts', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003602', 'descriptor_name': 'Cytotoxicity, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005333', 'descriptor_name': 'Fetus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005333', 'descriptor_name': 'Fetus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D059951', 'descriptor_name': 'HLA-G Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015395', 'descriptor_name': 'Histocompatibility Antigens Class I', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015395', 'descriptor_name': 'Histocompatibility Antigens Class I', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015395', 'descriptor_name': 'Histocompatibility Antigens Class I', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007106', 'descriptor_name': 'Immune Sera', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007141', 'descriptor_name': 'Immunoglobulin Fc Fragments', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007141', 'descriptor_name': 'Immunoglobulin Fc Fragments', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D011971', 'descriptor_name': 'Receptors, Immunologic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054340', 'descriptor_name': 'Receptors, KIR', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054345', 'descriptor_name': 'Receptors, KIR2DL4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054346', 'descriptor_name': 'Receptors, KIR2DL5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012995', 'descriptor_name': 'Solubility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014327', 'descriptor_name': 'Trophoblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.189.7.1093', 'pdf_url': 'https://rupress.org/jem/article-pdf/189/7/1093/1120405/98-1723.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2193010', 'pdf_url': 'https://europepmc.org/articles/pmc2193010?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10190900', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.189.7.1093', 'pdf_url': 'https://rupress.org/jem/article-pdf/189/7/1093/1120405/98-1723.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.78}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 38, 'referenced_works': ['https://openalex.org/W1541594543', 'https://openalex.org/W1574784499', 'https://openalex.org/W1575233708', 'https://openalex.org/W1579374155', 'https://openalex.org/W1629602182', 'https://openalex.org/W1882284170', 'https://openalex.org/W1906987668', 'https://openalex.org/W1950063835', 'https://openalex.org/W1964447317', 'https://openalex.org/W1964653209', 'https://openalex.org/W1977597577', 'https://openalex.org/W1985684774', 'https://openalex.org/W1994232628', 'https://openalex.org/W1995226124', 'https://openalex.org/W1996130880', 'https://openalex.org/W1999839845', 'https://openalex.org/W2003676228', 'https://openalex.org/W2014208459', 'https://openalex.org/W2015653720', 'https://openalex.org/W2022609860', 'https://openalex.org/W2038967602', 'https://openalex.org/W2047424019', 'https://openalex.org/W2054699270', 'https://openalex.org/W2064140853', 'https://openalex.org/W2078955788', 'https://openalex.org/W2083618683', 'https://openalex.org/W2084559051', 'https://openalex.org/W2116171543', 'https://openalex.org/W2123158636', 'https://openalex.org/W2144891041', 'https://openalex.org/W2147628746', 'https://openalex.org/W2152356426', 'https://openalex.org/W2160520392', 'https://openalex.org/W2172005924', 'https://openalex.org/W2387590621', 'https://openalex.org/W4313333731', 'https://openalex.org/W4313333864', 'https://openalex.org/W76522298'], 'related_works': ['https://openalex.org/W587341786', 'https://openalex.org/W4312094432', 'https://openalex.org/W2803531504', 'https://openalex.org/W2571232265', 'https://openalex.org/W23129031', 'https://openalex.org/W2192821761', 'https://openalex.org/W2090648490', 'https://openalex.org/W2014928916', 'https://openalex.org/W1991450596', 'https://openalex.org/W1861983754'], 'abstract_inverted_index': {'Human': [0], 'natural': [1], 'killer': [2, 7], '(NK)': [3], 'cells': [4, 85, 91, 138, 145, 174, 179], 'express': [5, 140, 147], 'several': [6], 'cell': [8, 128], 'immunoglobulin': [9], '(Ig)-like': [10], 'receptors': [11], '(KIRs)': [12], 'that': [13, 39, 79, 139, 146, 156, 175], 'inhibit': [14], 'their': [15], 'cytotoxicity': [16], 'upon': [17], 'recognition': [18], 'of': [19, 33, 63, 70, 117, 124, 134, 136], 'human': [20], 'histocompatibility': [21], 'leukocyte': [22], 'antigen': [23], '(HLA)': [24], 'class': [25, 95, 101, 149], 'I': [26, 96, 150], 'molecules': [27, 151], 'on': [28, 108], 'target': [29, 137, 144], 'cells.': [30, 120], 'Additional': [31], 'members': [32], 'the': [34, 61, 115, 127, 181], 'KIR': [35], 'family,': [36], 'including': [37, 152], 'some': [38], 'deliver': [40], 'activation': [41], 'signals,': [42], 'have': [43], 'unknown': [44], 'ligand': [45], 'specificity': [46], 'and': [47, 69, 73], 'function.': [48], 'One': [49], 'such': [50], 'KIR,': [51], 'denoted': [52], 'KIR2DL4,': [53], 'is': [54, 112, 159], 'structurally': [55], 'divergent': [56], 'from': [57], 'other': [58, 93, 99, 148], 'KIRs': [59], 'in': [60, 132], 'configuration': [62], 'its': [64, 71], 'two': [65], 'extracellular': [66], 'Ig': [67], 'domains': [68], 'transmembrane': [72], 'cytoplasmic': [74], 'domains.': [75], 'Here': [76], 'we': [77], 'show': [78], 'recombinant': [80], 'soluble': [81], 'KIR2DL4': [82, 111, 125, 165], 'binds': [83], 'to': [84, 90, 161, 170], 'expressing': [86, 92], 'HLA-G': [87, 157], 'but': [88, 142], 'not': [89, 143], 'HLA': [94, 100], 'molecules.': [97], 'Unlike': [98], 'I-specific': [102], 'KIRs,': [103], 'which': [104], 'are': [105], 'clonally': [106], 'distributed': [107], 'NK': [109, 119, 172], 'cells,': [110, 164], 'expressed': [113], 'at': [114, 180], 'surface': [116], 'all': [118], 'Furthermore,': [121], 'functional': [122], 'transfer': [123], 'into': [126], 'line': [129], 'NK-92': [130], 'resulted': [131], 'inhibition': [133], 'lysis': [135], 'HLA-G,': [141], 'HLA-E.': [153], 'Therefore,': [154], 'given': [155], 'expression': [158], 'restricted': [160], 'fetal': [162], 'trophoblast': [163, 178], 'may': [166], 'provide': [167], 'important': [168], 'signals': [169], 'maternal': [171], 'decidual': [173], 'interact': [176], 'with': [177], 'maternal-fetal': [182], 'interface': [183], 'during': [184], 'pregnancy.': [185]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2112179844', 'counts_by_year': [{'year': 2024, 'cited_by_count': 14}, {'year': 2023, 'cited_by_count': 11}, {'year': 2022, 'cited_by_count': 20}, {'year': 2021, 'cited_by_count': 27}, {'year': 2020, 'cited_by_count': 19}, {'year': 2019, 'cited_by_count': 18}, {'year': 2018, 'cited_by_count': 16}, {'year': 2017, 'cited_by_count': 26}, {'year': 2016, 'cited_by_count': 26}, {'year': 2015, 'cited_by_count': 33}, {'year': 2014, 'cited_by_count': 21}, {'year': 2013, 'cited_by_count': 41}, {'year': 2012, 'cited_by_count': 30}], 'updated_date': '2025-01-05T23:17:29.428532', 'created_date': '2016-06-24'}