Publication Information

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2641, 2646, 2684, 2698, 2749, 2763, 2783, 2806, 2820, 2827, 2838, 2842, 2846, 2851, 2919, 2926, 2934, 2957, 2978, 2984, 2989, 2994, 2998, 3015, 3045, 3048, 3061, 3064, 3193, 3232, 3251, 3255, 3262, 3280, 3286, 3306, 3468, 3508, 3560, 3564, 3570, 3587, 3610, 3614, 3620, 3623, 3627, 3679, 3705, 3723, 3748, 3803, 3809, 3818, 3824, 3831, 3838, 3849, 3852, 3856, 3867, 3931, 3955, 3963, 3989, 3999, 4168, 4188, 4239], 'mouse': [3, 30, 71, 176, 239, 266, 307, 412, 647, 651, 654, 657, 677, 715, 719, 722, 725, 745, 1124, 1145, 2248, 2447, 2612, 2642, 2648, 2675, 2699, 2717, 2732, 2800, 2864, 2875, 3008, 3050, 3409, 3472, 4009, 4242], 'EST': [4, 240, 2844], 'data': [5, 241, 2808], 'base': [6, 242], 'at': [7, 25, 180, 243, 261, 416, 477, 1056, 1127, 1140, 1340, 1372, 1437, 2260, 2272, 2736, 2993, 3514, 3602, 3685, 3880], 'GenBank™': [8, 244, 1353, 1385, 1450], 'with': [9, 245, 2590, 2988, 3014, 3310, 3672, 3914, 4179], 'known': [10, 246, 2647], 'tryptase': [11, 177, 247, 413, 486, 505, 534, 580, 610, 810, 838, 2080, 2249, 2279, 2512, 2828, 3051, 3565], 'cDNAs': [12, 248, 1331, 1363, 1428, 2958], 'resulted': [13, 249, 2818], 'in': [14, 83, 97, 103, 111, 127, 139, 170, 188, 212, 250, 319, 333, 339, 347, 363, 375, 406, 424, 448, 1067, 1122, 1336, 1368, 1433, 1860, 1925, 2020, 2075, 2152, 2280, 2395, 2517, 2566, 2582, 2588, 2611, 2640, 2725, 2805, 2819, 2911, 3027, 3056, 3070, 3083, 3192, 3234, 3261, 3305, 3323, 3459, 3474, 3480, 3489, 3503, 3569, 3586, 3607, 3657, 3668, 3693, 3713, 3739, 3871, 3883, 4095, 4147, 4244], 'identification': [16, 252, 2821], 'undiscovered': [18, 254], 'serine': [19, 48, 90, 209, 255, 284, 326, 445, 473, 621, 626, 630, 644, 665, 670, 689, 694, 698, 712, 733, 738, 840, 905, 1119, 1324, 1394, 1421, 1486, 1550, 2515, 2733, 3028, 3814], 'protease': [20, 49, 165, 210, 228, 256, 285, 401, 446, 464, 474, 664, 732, 1120, 1148, 1395, 1487, 2532, 2553, 2563, 2649, 2676, 2734, 2756, 3612, 3815], 'transcripts': [21, 257, 2789, 2856, 3260], 'whose': [22, 51, 258, 287], 'genes': [23, 178, 259, 414, 482, 985, 1052, 1105, 1136, 2564, 2634, 2650, 2706, 2735, 3021], 'reside': [24, 187, 260, 423, 1053], 'a': [26, 167, 219, 262, 403, 455, 1057, 1555, 1883, 2208, 2269, 2442, 2486, 2551, 2745, 3422, 3428, 3481, 3583, 3686, 3745, 3812, 3899, 4165], '1.5-Mb': [27, 263], 'complex': [28, 264], 'on': [29, 80, 265, 316, 2556, 2651, 2768, 2837, 2942, 3285], 'chromosome': [31, 194, 267, 430, 478, 1048, 1128, 2652, 2737, 2981, 3009], '17A3.3.': [32, 268, 1129], 'Mouse': [33, 269, 2769, 2985, 3487, 4007], 'tryptase-5': [34, 270], '(mT5),': [35, 271], 'tryptase-6': [36, 272], '(mT6),': [37, 273], 'and': [38, 61, 114, 121, 132, 141, 153, 159, 232, 274, 297, 350, 357, 368, 377, 389, 395, 468, 957, 993, 1106, 1114, 1329, 1357, 1361, 1389, 1426, 1454, 1507, 1532, 1537, 1575, 1583, 1647, 1934, 2111, 2265, 2385, 2448, 2569, 2574, 2579, 2601, 2700, 2772, 2777, 2787, 2834, 2854, 2872, 2916, 2923, 2929, 2931, 2947, 2973, 3060, 3141, 3188, 3258, 3413, 3420, 3427, 3441, 3491, 3499, 3510, 3594, 3622, 3645, 3710, 3726, 3734, 3792, 3798, 3827, 3969, 3983, 4002, 4010, 4082, 4152], 'mast': [39, 128, 275, 364, 640, 708, 1146], 'cell': [40, 276, 1147, 2456, 3417, 3424, 3430, 3443, 3457, 3670, 3727, 4172], 'protease-11': [41, 277], '(mMCP-11)': [42, 278], 'are': [43, 55, 134, 279, 291, 370, 980, 2142, 2572, 2576, 2638, 2721, 3068, 3237, 4093], 'new': [44, 89, 280, 325, 2714, 2824, 3482], 'members': [45, 281, 2539, 2825], 'this': [47, 283, 1091, 1131, 1346, 1378, 1443, 1547, 2278, 2636, 2668, 2709, 2816, 3864, 4245], 'superfamily': [50, 286, 2829], 'amino': [52, 288, 2086, 4139], 'acid': [53, 289, 2087, 4140], 'sequences': [54, 290, 1350, 1382, 1447, 2088, 2781, 2804, 2840, 2955, 3026, 3601, 4141], '36–54%': [56, 292], 'identical': [57, 293], 'to': [58, 62, 119, 294, 298, 355, 1004, 1100, 1553, 1653, 1858, 1881, 1936, 2252, 2391, 2440, 2452, 2469, 2472, 2526, 2545, 2657, 2662, 2681, 2689, 2794, 2949, 3037, 3249, 3278, 3466, 3678, 3754, 3807, 3834, 3929, 4155, 4187, 4198, 4234], 'each': [59, 164, 227, 295, 400, 463, 1544, 2660, 2754, 3558, 3910, 3935, 4175], 'other': [60, 64, 233, 296, 300, 469, 3324], 'their': [63, 84, 299, 320, 1348, 1380, 1445, 1859, 2577, 2621, 2951, 3515, 3603, 3984, 4136], '10': [65, 301, 1135, 3937], 'family': [66, 302, 1548, 2513, 2538, 2637], 'members.': [67, 303], 'The': [68, 147, 196, 304, 383, 432, 472, 1043, 1117, 2202, 2507, 2543, 2908, 2937, 2953, 3004, 3053, 3439, 3844, 4192, 4201], '13': [69, 174, 305, 410], 'functional': [70, 175, 224, 306, 411, 460, 2632, 2751], 'proteases': [72, 308, 1540, 1551, 2516, 2610, 2719, 3854, 4161, 4243], 'can': [73, 309, 2071, 2463], 'be': [74, 310, 1654, 2072, 2441, 2624, 2679], 'subdivided': [75, 311], 'into': [76, 312, 1870, 2156, 3942], 'two': [77, 214, 313, 450, 2146, 3408, 3415], 'subgroups': [78, 314], 'based': [79, 315], 'conserved': [81, 317, 3024], 'features': [82, 318], 'propeptides.': [85, 321], 'Of': [86, 172, 322, 408, 1526], 'three': [88, 324, 2713, 2823], 'proteases,': [91, 327, 1528], 'mT6': [92, 131, 328, 367, 2927], 'is': [93, 100, 108, 124, 329, 336, 344, 360, 1054, 1093, 1096, 1561, 1923, 2207, 2485, 2554, 2618, 2627, 3454], 'most': [94, 330], 'widely': [95, 331], 'expressed': [96, 102, 110, 126, 138, 332, 338, 346, 362, 374, 1536, 2724, 3611], 'tissues.': [98, 334], 'mT5': [99, 120, 144, 335, 356, 380, 2920, 3872], 'preferentially': [101, 109, 337, 345, 2163, 2453], 'smooth': [104, 340], 'muscle,': [105, 341, 2866], 'whereas': [106, 342], 'mMCP-11': [107, 123, 133, 154, 343, 359, 369, 390, 2778, 2855, 3259, 3275, 3434, 3735], 'spleen': [113, 349, 2867], 'bone': [115, 351, 678, 746, 2876], 'marrow.': [116, 352], 'In': [117, 353, 1856, 2016, 2683, 2708, 3557, 3863, 3934], 'contrast': [118, 354], 'mT6,': [122, 152, 358, 388, 656, 724, 2776, 2833, 2853, 2963, 3257, 3497, 3733], 'also': [125, 361, 1560, 1649, 2250, 2728, 3011, 3436, 3736, 3847], 'cells.': [129, 365], 'Although': [130, 366, 2084], 'constitutively': [135, 371], 'secreted': [136, 372], 'when': [137, 373, 2284, 2570], 'mammalian': [140, 376, 3504, 3571, 3813], 'insect': [142, 378, 3742, 3876], 'cells,': [143, 379], 'remains': [145, 381], 'membrane-associated.': [146, 382], 'fact': [148, 384], 'that': [149, 163, 186, 385, 399, 422, 483, 998, 1094, 1143, 1559, 1565, 1580, 2068, 2276, 2446, 2458, 2481, 2548, 2620, 2720, 2730, 2959, 3022, 3298, 3506, 4089], 'recombinant': [150, 386, 1539, 1581, 1865, 2392, 2490, 3496, 3522, 3756, 3839, 3853], 'mT5,': [151, 387, 653, 721, 2775, 2832, 2852, 2962, 3256, 3591, 3732, 4148], 'possess': [155, 391, 1585, 3596], 'non-identical': [156, 392], 'expression': [157, 393, 2398, 3287, 3469, 3572, 3749, 3865], 'patterns': [158, 394], 'substrate': [160, 396, 1587, 2210, 2488], 'specificities': [161, 397, 1588], 'suggests': [162, 398], 'has': [166, 402, 2268, 2521], 'unique': [168, 404, 1556], 'function': [169, 405, 2467, 2607], 'vivo.': [171, 407, 2153, 2583, 2726], 'identified': [179, 415, 1139, 2843], 'complex,': [182, 418], '12': [183, 419, 2731], 'have': [184, 420, 1332, 1351, 1364, 1383, 1429, 1448, 1534, 1650, 2739, 3445], 'orthologs': [185, 421, 2623], 'syntenic': [190, 426], 'region': [191, 427, 1045, 3562], 'human': [193, 429, 485, 1047, 2449, 2599, 2615, 2665, 2701, 2740, 3646, 4011], '16p13.3.': [195, 431], 'establishment': [197, 433], 'these': [199, 435, 1051, 1527, 2019, 2145, 2609, 2691, 2704, 2912, 3057, 3084, 3235, 3460, 3608, 4090, 4160], 'ortholog': [200, 436], 'pairs': [201, 437], 'helps': [202, 438], 'clarify': [203, 439], 'evolutionary': [205, 441, 1098], 'relationship': [206, 442], 'locus': [211, 447, 997, 1121], 'species.': [215, 451], 'This': [216, 452, 1920, 2584, 2742], 'information': [217, 453, 2743], 'provides': [218, 454, 2744], 'useful': [220, 456, 2746], 'framework': [221, 457, 2747], 'for': [222, 458, 1090, 2748, 2796, 2918, 2925, 2933, 2997, 3001, 3019, 3044, 3197, 3449, 3521, 3718, 3887, 3962, 3970], 'analysis': [225, 461, 2696, 2752, 4085], 'using': [229, 465, 2758, 2859, 3295, 3744, 3859, 3974, 3988], 'gene': [230, 466, 475, 2397], 'targeting': [231, 467], 'molecular': [234, 470, 2530], 'approaches.': [235, 471, 2760], 'cluster': [476], '16p13.3': [479], 'contains': [480], 'encode': [484, 1000, 1144, 2960, 3023], 'α': [487, 2203], '(1.Miller': [488], 'J.S.': [489, 564, 964], 'Westin': [490], 'E.H.': [491], 'Schwartz': [492, 567], 'L.B.': [493, 568], 'J.': [494, 569, 770, 800, 822, 860, 883, 888, 970, 1027, 1072, 1159, 1222, 1256, 1287, 1307, 1464, 1469, 1605, 1632, 1635, 1673, 1705, 1738, 1772, 1810, 1846, 1904, 1954, 1957, 1981, 1998, 2057, 2099, 2186, 2229, 2307, 2345, 2370, 2421, 2502, 2900, 3099, 3163, 3220, 3339, 3360, 3375, 3394, 3541, 3775, 4023, 4028, 4075, 4118, 4220], 'Clin.': [495, 570, 2372], 'Investig.': [496, 571], '1989;': [497, 4223], '84:': [498], '1188-1195Crossref': [499], 'PubMed': [500, 529, 558, 575, 604, 781, 805, 833, 871, 899, 923, 974, 1038, 1083, 1168, 1196, 1233, 1267, 1292, 1318, 1415, 1480, 1502, 1521, 1616, 1684, 1716, 1749, 1783, 1821, 1851, 1915, 1992, 2011, 2062, 2108, 2137, 2197, 2240, 2318, 2356, 2382, 2432, 3108, 3136, 3174, 3345, 3400, 3552, 3786, 4037, 4056, 4129, 4229], 'Scopus': [501, 530, 559, 576, 605, 782, 806, 834, 872, 900, 924, 975, 1039, 1084, 1197, 1234, 1268, 1293, 1319, 1416, 1481, 1503, 1522, 1617, 1685, 1717, 1750, 1784, 1822, 1852, 1916, 1993, 2012, 2063, 2138, 2198, 2241, 2319, 2357, 2433, 3137, 3175, 3346, 3401, 3553, 3787, 4057, 4130], '(177)': [502], 'Google': [503, 532, 561, 578, 607, 784, 808, 836, 874, 902, 926, 955, 977, 1041, 1086, 1169, 1199, 1236, 1270, 1295, 1321, 1418, 1483, 1505, 1524, 1619, 1640, 1687, 1719, 1752, 1786, 1824, 1854, 1918, 1962, 1995, 2014, 2065, 2109, 2140, 2200, 2243, 2321, 2359, 2383, 2435, 2905, 3109, 3139, 3177, 3225, 3348, 3365, 3380, 3403, 3555, 3789, 4038, 4059, 4080, 4132, 4230], 'Scholar),': [504, 533, 579, 608, 809, 837, 875, 903, 956, 1170, 1200, 1237, 1322, 1419, 1484, 1506, 2384, 2906, 3110, 3140, 3790, 4081], 'βI': [506, 1869, 1933], '(2.Vanderslice': [507, 536, 582], 'P.': [508, 537, 583, 968], 'Ballinger': [509, 538, 584], 'S.M.': [510, 514, 539, 543, 585, 589], 'Tam': [511, 540, 586], 'E.K.': [512, 541, 587], 'Goldstein': [513, 542, 588], 'Craik': [515, 544, 590, 1770], 'C.S.': [516, 545, 591, 1771], 'Caughey': [517, 546, 592, 820, 886, 1467], 'G.H.': [518, 547, 593, 787, 821, 887, 1468], 'Proc.': [519, 548, 594, 1186, 2127, 3126], 'Natl.': [520, 549, 595, 1187, 2128, 3127], 'Acad.': [521, 550, 596, 1188, 2129, 3128], 'Sci.': [522, 551, 597, 1189, 2130, 3129], 'U.': [523, 552, 598, 1190, 2000, 2131, 3130], 'S.': [524, 553, 599, 847, 1014, 1191, 1302, 1660, 1793, 1797, 2132, 2328, 2332, 2404, 2408, 2494, 3131, 3336, 3528, 4217], 'A.': [525, 554, 600, 757, 857, 1024, 1192, 1209, 1253, 1298, 1598, 1670, 1757, 1831, 2133, 2222, 2294, 2893, 3132, 3150, 3213, 3538, 3768, 4103, 4115], '1990;': [526, 555, 572, 601], '87:': [527, 556, 602], '3811-3815Crossref': [528, 557, 603], '(202)': [531, 560, 606], 'βII': [535], 'Scholar,': [562, 785, 927, 1271, 1296, 1620, 1688, 1720, 1753, 1787, 1825, 1963, 1996, 2322, 3349, 3366, 3381, 4039, 4060], '3.Miller': [563], 'Moxley': [565], 'G.': [566, 1630, 1801, 1952, 2006, 2047, 2336, 2412, 4101], '86:': [573], '864-870Crossref': [574], '(153)': [577], 'βIII': [581], 'transmembrane': [609, 617, 685], '(TMT)': [611], '1The': [612], 'abbreviations': [613, 681], 'used': [614, 682, 2791, 2910, 3036, 3055, 3079, 3248, 3465, 3928, 4233], 'are:': [615, 683], 'TMT,': [616, 684], 'tryptase;': [618, 686], 'Bssp-4,': [619, 687], 'brain-specific': [620, 688, 1420], 'protease-4;': [622, 690], 'Disp,': [623, 691], 'distal': [624, 692, 1392], 'intestinal': [625, 693, 1393], 'protease;': [627, 645, 649, 695, 713, 717], 'Esp-1,': [628, 696], 'eosinophil': [629, 697, 904], 'protease-1;': [631, 671, 699, 739], 'G3PDH,': [632, 700], 'glyceraldehyde-3-phosphate': [633, 701], 'dehydrogenase;': [634, 702], 'GPI,': [635, 703], 'glycosylphosphatidylinositol;': [636, 704], 'IL,': [637, 705], 'interleukin;': [638, 706], 'MC,': [639, 707], 'cell;': [641, 709], 'Isp,': [642, 710], 'implantation': [643, 711, 1485], 'mMCP,': [646, 714], 'MC': [648, 716, 3325, 3410, 3461], 'mT4,': [650, 718, 2786, 2961, 3590, 3791], 'tryptase-4;': [652, 720], 'tryptase-5;': [655, 723], 'tryptase-6;': [658, 726], 'PPACK,': [659, 727], 'd-phenylalanyl-l-prolyl-l-arginine': [660, 728, 4203], 'chloromethyl': [661, 729, 4204], 'ketone;': [662, 730], 'PRSS,': [663, 731], 'member': [666, 734, 841, 1545], 'S;': [667, 735], 'Tessp1,': [668, 736], 'testis': [669, 737, 1323], 'PNGaseF,': [672, 740], 'peptide:N-glycosidase;': [673, 741], 'pNA,': [674, 742], 'p-nitroanilide;': [675, 743], 'mBMMCs,': [676, 744], 'marrow-derived': [679, 747, 2877], 'MCs.1The': [680], 'MCs./tryptase': [748], 'γ': [749], '(4.Wong': [750, 1202, 2287, 3143], 'G.W.': [751, 845, 1012, 1203, 1241, 1592, 1628, 1658, 1789, 1950, 2216, 2288, 2324, 2400, 2496, 3144, 3526, 3762], 'Tang': [752, 1204, 1697, 2289, 3145], 'Y.': [753, 761, 853, 1020, 1205, 1213, 1666, 1698, 2290, 2298, 3146, 3154, 3534], 'Feyfant': [754, 1206, 2291, 3147, 4112], 'E.': [755, 1207, 2292, 2881, 3148, 3201, 4113], 'Šali': [756, 856, 1023, 1208, 1252, 1597, 1669, 2221, 2293, 3149, 3537, 3767, 4114], 'Li': [758, 760, 850, 1017, 1210, 1212, 1242, 1663, 1691, 1699, 1802, 2295, 2297, 2337, 2413, 3151, 3153, 3531], 'L.': [759, 817, 851, 1018, 1211, 1243, 1664, 1692, 1803, 2004, 2296, 2338, 2414, 3152, 3532], 'Huang': [762, 1214, 2299, 3155], 'C.': [763, 960, 1215, 1590, 1622, 1690, 1722, 1888, 1944, 1965, 2043, 2170, 2214, 2300, 3156, 3760, 4099, 4109], 'Friend': [764, 1216, 1623, 1730, 1896, 1945, 1973, 2178, 2301, 3157, 3352, 3388, 4063], 'D.S.': [765, 1152, 1154, 1175, 1181, 1217, 1624, 1731, 1897, 1946, 1974, 2092, 2094, 2116, 2122, 2179, 2302, 3092, 3094, 3115, 3121, 3158, 3353, 3389, 4064], 'Krilis': [766, 854, 1021, 1218, 1246, 1667, 1693, 1806, 2303, 2341, 2417, 2497, 3159, 3535], 'S.A.': [767, 855, 1022, 1219, 1247, 1668, 1694, 1807, 2304, 2342, 2418, 2498, 3160, 3536], 'Stevens': [768, 858, 1025, 1184, 1220, 1254, 1603, 1633, 1671, 1703, 1736, 1808, 1902, 1955, 1979, 2125, 2184, 2227, 2305, 2343, 2419, 2499, 2898, 3124, 3161, 3218, 3337, 3358, 3373, 3539, 3773, 4073, 4116], 'R.L.': [769, 859, 1026, 1185, 1221, 1255, 1604, 1634, 1672, 1704, 1737, 1809, 1903, 1956, 1980, 2126, 2185, 2228, 2306, 2344, 2420, 2500, 2899, 3125, 3162, 3219, 3338, 3359, 3374, 3540, 3774, 4074, 4117], 'Biol.': [771, 823, 861, 889, 1028, 1160, 1223, 1257, 1308, 1470, 1606, 1674, 1706, 1739, 1773, 1811, 1905, 1982, 2100, 2187, 2230, 2308, 2346, 2422, 3100, 3164, 3542, 3776, 4029, 4119, 4221], 'Chem.': [772, 824, 862, 890, 1029, 1161, 1224, 1258, 1309, 1471, 1607, 1675, 1707, 1740, 1774, 1812, 1906, 1983, 2101, 2188, 2231, 2309, 2347, 2423, 3101, 3165, 3543, 3777, 4030, 4120, 4222], '1999;': [773, 825, 952, 1225, 1708, 2310, 2374, 3166, 3397], '274:': [774, 826, 1226, 1709, 2311, 3167], '30784-30793Abstract': [775, 1227, 2312, 3168], 'Full': [776, 778, 828, 830, 866, 868, 894, 896, 1033, 1035, 1165, 1228, 1230, 1262, 1264, 1313, 1315, 1475, 1477, 1611, 1613, 1679, 1681, 1711, 1713, 1744, 1746, 1778, 1780, 1816, 1818, 1910, 1912, 1987, 1989, 2105, 2192, 2194, 2235, 2237, 2313, 2315, 2351, 2353, 2377, 2379, 2427, 2429, 3105, 3169, 3171, 3547, 3549, 3781, 3783, 4034, 4124, 4126, 4226], 'Text': [777, 779, 829, 831, 867, 869, 895, 897, 1034, 1036, 1166, 1229, 1231, 1263, 1265, 1314, 1316, 1476, 1478, 1612, 1614, 1680, 1682, 1712, 1714, 1745, 1747, 1779, 1781, 1817, 1819, 1911, 1913, 1988, 1990, 2106, 2193, 2195, 2236, 2238, 2314, 2316, 2352, 2354, 2378, 2380, 2428, 2430, 3106, 3170, 3172, 3548, 3550, 3782, 3784, 4035, 4125, 4127, 4227], 'PDF': [780, 832, 870, 898, 1037, 1167, 1232, 1266, 1317, 1479, 1615, 1683, 1715, 1748, 1782, 1820, 1914, 1991, 2107, 2196, 2239, 2317, 2355, 2381, 2431, 3107, 3173, 3551, 3785, 4036, 4128, 4228], '(84)': [783, 1235, 2320, 3176], '5.Caughey': [786], 'Raymond': [788], 'W.W.': [789], 'Blount': [790, 818], 'J.L.': [791, 819, 933, 1755], 'Hau': [792, 879, 1460], 'L.W.': [793, 880, 1461], 'Pallaoro': [794], 'M.': [795, 813, 909, 913, 1402, 1761, 1769, 1839, 2002, 2051, 4021, 4027, 4107], 'Wolters': [796, 884, 1465], 'P.J.': [797, 885, 1466, 1727, 1893, 1970, 2175], 'Verghese': [798], 'G.M.': [799], 'Immunol.': [801, 1636, 1847, 1958, 2058, 2373, 2901, 3221, 3361, 3376, 4052, 4076], '2000;': [802, 1080, 1412, 2008, 4121], '164:': [803], '6566-6575Crossref': [804], '(103)': [807], 'δ': [811], '(6.Pallaoro': [812], 'Fejzo': [814], 'M.S.': [815, 849, 1016, 1245, 1662, 3530], 'Shayesteh': [816], '3355-3362Abstract': [827], '(121)': [835], 'ϵ/protease': [839], 'S22': [842], '(PRSS22)': [843], '(7.Wong': [844, 1011, 1657, 3525], 'Yasuda': [846, 1013, 1659, 1792, 2327, 2403, 3527], 'Madhusudhan': [848, 1015, 1244, 1661, 3529], 'Yang': [852, 1019, 1665, 3533], '2001;': [863, 1030, 1259, 1289, 1499, 1518, 1676, 1741, 1775, 1907, 1984, 2189, 3544], '276:': [864, 1031, 1260, 1677, 1742, 1776, 1908, 1985, 2190, 3545], '49169-49182Abstract': [865, 1032, 1678, 3546], '(47)': [873, 1040, 1686, 3554], 'pancreasin/marapsin/PRSS27': [876], '(8.Bhagwandin': [877, 1458], 'V.J.': [878, 1459], 'Mallen-St.': [881, 1462], 'Clair': [882, 1463], '2003;': [891, 971, 1472, 2503], '278:': [892, 1473], '3363-3371Abstract': [893, 1474], '(24)': [901, 1482], 'protease-1': [906, 1325], '(Esp-1)/testisin/PRSS21': [907], '(9.Inoue': [908], 'Kanbe': [910], 'N.': [911, 1179, 1594, 1835, 2120, 2218, 3119, 3330, 3351, 3370, 3764, 4062], 'Kurosawa': [912], 'Kido': [914], 'H.': [915, 2049, 3383], 'Biochem.': [916, 969, 1288], 'Biophys.': [917, 1410], 'Res.': [918, 951], 'Commun.': [919], '1998;': [920, 1637, 1959], '252:': [921], '307-312Crossref': [922], '(36)': [925], '10.Hooper': [928], 'J.D.': [929, 1275], 'Nicol': [930], 'D.L.': [931], 'Dickinson': [932], 'Eyre': [934], 'H.J.': [935], 'Scarman': [936], 'A.L.': [937, 962, 1273], 'Normyle': [938, 1282], 'J.F.': [939, 1283], 'Stuttgen': [940], 'M.A.': [941], 'Douglas': [942], 'M.L.': [943, 1279], 'Loveland': [944], 'K.A.': [945], 'Sutherland': [946], 'G.R.': [947], 'Antalis': [948, 1284], 'T.M.': [949, 1285], 'Cancer': [950], '59:': [953], '3199-3205PubMed': [954], 'EOS': [958], '(11.Chen': [959], 'Darrow': [961], 'Qi': [963, 1794, 2329, 2405], "D'Andrea": [965], 'M.R.': [966], 'Andrade-Gordon': [967], '374:': [972], '97-107Crossref': [973], '(31)': [976], 'Scholar).': [978, 1042, 1087, 1525, 1641, 1855, 1919, 2015, 2201, 2244, 2360, 2436, 2506, 3178, 3226, 3404, 3556, 4133], 'There': [979], 'five': [981], 'additional': [982, 3290], 'nonpeptidase': [983], 'homolog': [984], '(currently': [986], 'designated': [987], 'as': [988, 2792, 2831, 3080, 3321, 3518, 3582], 'hSPL-2,': [989], '-3,': [990], '-4,': [991], '-6,': [992], '-7)': [994], 'within': [995], 'probably': [999], 'non-functional': [1001], 'proteins': [1002, 3968], 'due': [1003, 2468], 'presence': [1006, 3046, 3194, 3307, 3964], 'premature': [1008], 'translation-termination': [1009], 'codons': [1010], 'subtelomeric': [1044], '16': [1049], 'where': [1050, 2568, 2703], 'mutating': [1055], 'rate': [1058], '∼300-fold': [1059], 'faster': [1060], 'than': [1061, 1564], 'rest': [1063], 'genome': [1066, 1125, 2600, 2695], 'males': [1068], '(12.Badge': [1069], 'R.M.': [1070], 'Yardley': [1071], 'Jeffreys': [1073], 'A.J.': [1074, 1400], 'Armour': [1075], 'J.A.': [1076, 1765, 1805, 2340, 2416, 3393, 4017], 'Hum.': [1077], 'Mol.': [1078], 'Genet.': [1079], '9:': [1081], '1239-1244Crossref': [1082], '(59)': [1085], 'One': [1088], 'explanation': [1089], 'finding': [1092], 'there': [1095, 3453], 'strong': [1097], 'pressure': [1099], 'expand': [1101], 'some': [1102], 'delete': [1107], 'others': [1108], 'because': [1109], 'respective': [1112], 'beneficial': [1113, 2578], 'adverse': [1115, 2580], 'roles.': [1116], 'corresponding': [1118, 2622, 2664], 'resides': [1126], 'When': [1130, 2154], 'study': [1132, 4246], 'was': [1133, 2478, 2655, 2671, 3012, 3035, 3182, 3246, 3437, 3567, 3821, 3873, 3912, 3927, 4177, 4232], 'initiated,': [1134], 'had': [1137, 2540, 3299], 'been': [1138, 1334, 1366, 1431, 1535, 1651, 2541, 3300, 3446], 'site': [1142, 2996], '(mMCP)': [1149], '6': [1150], '(13.Reynolds': [1151, 2091, 3091], 'Gurley': [1153, 1180, 2093, 2121, 3093, 3120], 'Austen': [1155, 1182, 2095, 2123, 2896, 3095, 3122, 3216, 3333, 3356, 3371, 3390, 4067], 'K.F.': [1156, 1183, 2096, 2124, 2897, 3096, 3123, 3217, 3334, 3357, 3372, 3391, 4068], 'Serafin': [1157, 2097, 3097], 'W.E.': [1158, 2098, 3098], '1991;': [1162, 2102, 3102, 4053], '266:': [1163, 2103, 3103], '3847-3853Abstract': [1164, 2104, 3104], 'mMCP-7': [1171, 1584, 2112, 2162, 2212, 3111, 3758, 4087], '(14.McNeil': [1172, 2113, 3112], 'H.P.': [1173, 1829, 2114, 3113, 3332, 4070], 'Reynolds': [1174, 2115, 3114], 'Schiller': [1176, 2117, 3116, 4071], 'V.': [1177, 2118, 3117, 4072], 'Ghildyal': [1178, 1593, 2119, 2217, 3118, 3329, 3369, 3763], '1992;': [1193, 2134, 3133, 3342], '89:': [1194, 2135, 3134], '11174-11178Crossref': [1195, 2136, 3135], '(127)': [1198, 1751, 1917, 1994, 2139, 2199, 3138], 'mTMT': [1201, 2267, 2788, 3142], 'tryptase-4': [1238], '(mT4)/mEsp-1/mTesp5/mTestisin/mPrss21': [1239], '(15.Wong': [1240], 'Gurish': [1248, 1595, 2219, 3765], 'M.F.': [1249, 1596, 2220, 3328, 3766], 'Rothenberg': [1250], 'M.E.': [1251], '20648-20658Abstract': [1261], '(32)': [1269], '16.Scarman': [1272], 'Hooper': [1274], 'Boucaut': [1276], 'K.J.': [1277], 'Sit': [1278], 'Webb': [1280], 'G.C.': [1281, 1841], 'Eur.': [1286], '268:': [1290], '1250-1258Crossref': [1291], '(34)': [1294, 4131], '17.Honda': [1297], 'Yamagata': [1299], 'K.': [1300, 1304, 1696, 1759, 1833, 4105], 'Sugiura': [1301], 'Watanabe': [1303], 'Baba': [1305], 'T.': [1306, 4043, 4045], '2002;': [1310, 1813, 1848, 2059, 2348, 2424], '277:': [1311, 1814, 2349, 2425], '16976-16984Abstract': [1312], '(110)': [1320], '(mTessp1),': [1326], '2Although': [1327, 1424], 'mBssp-4': [1328, 1360, 1425, 3500], 'mTessp1': [1330, 1362, 1427, 3595], 'not': [1333, 1365, 1430, 2672, 2722, 3407, 4238], 'described': [1335, 1367, 1432, 3322, 3519], 'any': [1337, 1369, 1434, 4158], 'scientific': [1338, 1370, 1435], 'publication': [1339, 1371, 1436], 'time': [1342, 1374, 1439], 'submission': [1344, 1376, 1441], 'paper,': [1347, 1379, 1444], 'nucleotide': [1349, 1381, 1446, 2780, 2839, 2954], 'accession': [1354, 1386, 1451], 'numbers': [1355, 1387, 1452, 1940], 'BAB20262': [1356, 1388, 1453], 'BAB68561,': [1358, 1390, 1455], 'respectively.2Although': [1359], 'respectively.': [1391, 2907], '(mDisp)': [1396], '(18.Shaw-Smith': [1397], 'C.J.': [1398], 'Coffey': [1399], 'Leversha': [1401], 'Freeman': [1403], 'T.C.': [1404], 'Bentley': [1405], 'D.R.': [1406], 'Walters': [1407], 'J.R.': [1408], 'Biochim.': [1409], 'Acta.': [1411], '1490:': [1413], '131-136Crossref': [1414], '(10)': [1417], 'protease-4': [1422], '(mBssp-4)': [1423], 'respectively./4733401N09Rik,': [1456], 'pancreasin': [1457], '(mIsp)': [1488], '1': [1489, 3948], "(19.O'Sullivan": [1490], 'C.M.': [1491, 1510], 'Rancourt': [1492, 1496, 1513, 1515], 'S.L.': [1493, 1514], 'Liu': [1494, 1511, 1832], 'S.Y.': [1495, 1512], 'D.E.': [1497, 1516], 'Reproduction.': [1498, 1517], '122:': [1500, 1519], '61-71Crossref': [1501], '(57)': [1504], 'mIsp-2': [1508, 2974], "(20.O'Sullivan": [1509], '235-244Crossref': [1520], '(37)': [1523, 1853], 'only': [1529], 'mMCP-6,': [1530, 2784, 2964, 3757], 'mMCP-7,': [1531, 2266, 2785, 2965], 'mT4': [1533], 'functionally': [1541, 1655, 2715], 'characterized.': [1542], 'Nevertheless,': [1543], 'appears': [1552, 2251, 2439], 'contain': [1554, 3433, 4013, 4162], 'substrate-binding': [1557], 'cleft': [1558], 'more': [1562], 'restricted': [1563], 'pancreatic': [1567], 'trypsin.': [1568], 'Screening': [1569], 'phage': [1571], 'display': [1572], 'peptide': [1573, 3025, 3618, 3820, 3846], 'libraries': [1574, 2861, 3042], 'varied': [1576, 2518, 2807, 3049, 3311, 3471, 4240], 'chromogenic': [1577], 'substrates': [1578], 'confirmed': [1579], 'mMCP-6': [1582, 1866, 1935, 2090, 2264, 3090], 'different': [1586, 1656, 2149, 3263], '(21.Huang': [1589, 2213, 3759], 'Wong': [1591, 1627, 1949, 2215, 2495, 3761], 'Matsumoto': [1599, 2223, 3769], 'R.': [1600, 2224, 3770, 4066], 'Qiu': [1601, 1625, 1947, 2225, 3771, 4110], 'W.T.': [1602, 1626, 1948, 2226, 3772, 4111], '1997;': [1608, 2232, 3778], '272:': [1609, 2233, 3779], '31885-31893Abstract': [1610, 2234, 3780], '(98)': [1618, 2242, 3788], '22.Huang': [1621], 'Morales': [1629, 1951, 4100], 'Hunt': [1631, 1701, 1844, 1953], '160:': [1638, 1960], '1910-1919PubMed': [1639, 1961], 'hTryptases': [1642, 3793], 'α,': [1643, 3794], 'βI,': [1644, 3795], 'TMT/γ,': [1645, 3797], 'δ,': [1646], 'ϵ': [1648, 2492, 3524], 'shown': [1652], '23.Huang': [1689], 'Chanasyk': [1695, 4104], 'Z.': [1700], 'J.E.': [1702, 1845], '19670-19676Abstract': [1710], '(75)': [1718], '24.Huang': [1721, 1964], 'De': [1723, 1889, 1966, 2171], 'Sanctis': [1724, 1890, 1967, 2172], 'G.T.': [1725, 1891, 1968, 2173], "O'Brien": [1726, 1892, 1969, 2174], 'Mizgerd': [1728, 1894, 1971, 2176], 'J.P.': [1729, 1895, 1972, 2177, 2895, 3215], 'Drazen': [1732, 1898, 1975, 2180], 'J.M.': [1733, 1899, 1976, 2181, 2887, 3207], 'Brass': [1734, 1900, 1977, 2182], 'L.F.': [1735, 1901, 1978, 2183], '26276-26284Abstract': [1743, 1909, 1986, 2191], '25.Harris': [1754], 'Niles': [1756], 'Burdick': [1758], 'Maffitt': [1760], 'Backes': [1762], 'B.J.': [1763], 'Ellman': [1764], 'Kuntz': [1766], 'I.': [1767, 3072], 'Haak-Frendscho': [1768], '34941-34947Abstract': [1777], '(56)': [1785], '26.Wong': [1788, 2323], 'Foster': [1790, 2325, 2401], 'P.S.': [1791, 1837, 2326, 2402], 'J.C.': [1795, 2330, 2406], 'Mahalingam': [1796, 2331, 2407], 'Mellor': [1798, 2333, 2409], 'E.A.': [1799, 2334, 2410], 'Katsoulotos': [1800, 2335, 2411], 'Boyce': [1804, 2339, 2415, 3392], '41906-41915Abstract': [1815, 2350, 2426], '(68)': [1823, 2358, 2434], '27.Wang': [1826], 'H.W.': [1827], 'McNeil': [1828, 3331, 4069], 'Husain': [1830], 'Tedla': [1834], 'Thomas': [1836], 'Raftery': [1838], 'King': [1840], 'Cai': [1842], 'Z.Y.': [1843], '169:': [1849], '5145-5152Crossref': [1850], 'regard': [1857], 'vivo': [1861, 2021], 'function,': [1862], 'administration': [1863], 'or': [1867, 2802, 3318, 3406, 4171, 4237], 'hTryptase': [1868, 1932, 2491, 3523], 'lungs': [1872], 'significantly': [1873], 'enhances': [1874], 'ability': [1876, 1929, 2471, 2544], 'MC-deficient': [1878], 'W/Wv': [1879], 'mice': [1880, 2077], 'combat': [1882], 'Klebsiella': [1884], 'pneumoniae': [1885], 'infection': [1886], '(24.Huang': [1887, 2169], 'protective': [1921], 'effect': [1922], 'mediated,': [1924], 'part,': [1926, 2589], 'by': [1927, 2078, 2693, 3302, 3842, 3960, 3973, 4210], 'both': [1931, 3669], 'selectively': [1937, 2549], 'recruit': [1938], 'large': [1939], 'neutrophils': [1942], '(22.Huang': [1943], '28.Hallgren': [1997], 'Karlson': [1999], 'Poorafshar': [2001], 'Hellman': [2003], 'Pejler': [2005], 'Biochemistry.': [2007], '39:': [2009], '13068-13077Crossref': [2010], '(67)': [2013], 'support': [2017], 'findings,': [2022], 'Oh': [2023], 'et': [2024, 4212], 'al.': [2025, 4213], '(29.Oh': [2026], 'S.W.': [2027], 'Pae': [2028], 'C.I.': [2029], 'Lee': [2030], 'D.K.': [2031], 'Jones': [2032], 'F.': [2033], 'Chiang': [2034], 'G.K.': [2035], 'Kim': [2036], 'H.O.': [2037], 'Moon': [2038], 'S.H.': [2039], 'Cao': [2040], 'B.': [2041], 'Ogbu': [2042], 'Jeong': [2044], 'K.W.': [2045], 'Kozu': [2046], 'Nakanishi': [2048], 'Kahn': [2050], 'Chi': [2052], 'E.Y.': [2053], 'Henderson': [2054], 'Jr,': [2055], 'W.R.': [2056], '168:': [2060], '1992-2000Crossref': [2061], '(122)': [2064], 'Scholar)': [2066, 2110, 2141, 4231], 'noted': [2067, 2813, 3268], 'neutrophil': [2069], 'recruitment': [2070], 'inhibited': [2073], 'substantially': [2074], 'ovalbumin-treated': [2076], 'tetramer': [2081], 'inhibitor': [2082], 'MOL-6131.': [2083], '71%': [2143], 'identical,': [2144], 'tryptases': [2147, 3473, 3972, 4012], 'exhibit': [2148], 'biologic': [2150], 'activities': [2151], 'placed': [2155, 3568, 3822], 'peritoneal': [2158], 'cavities': [2159], 'mice,': [2161], 'induces': [2164], 'extravasation': [2166], 'eosinophils': [2168], 'chain': [2204], 'fibrinogen': [2206], 'physiologic': [2209], 'Thus,': [2245, 3179, 3277, 3452, 3606, 3817, 4154], 'latter': [2247], 'help': [2253], 'prevent': [2254], 'formation': [2256], 'fibrin/platelet': [2258], 'clots': [2259], 'inflammatory': [2261, 2519], 'sites.': [2262], 'Unlike': [2263], 'membrane-spanning': [2270], 'domain': [2271, 3625, 3833, 3870], 'its': [2273, 2470, 2602, 2663], 'C': [2274, 3516, 3604], 'terminus': [2275], 'anchors': [2277], 'plasma': [2282], 'membrane': [2283], 'MCs': [2285, 2361, 2450, 2878, 3088], 'degranulate': [2286], 'physically': [2362, 2460], 'contact': [2363], 'T': [2364, 2389, 3423], 'cells': [2365, 2390, 3233, 3505, 3635, 3651, 3707, 3743, 3801, 3877], '(30.Mekori': [2366], 'Y.A.': [2367], 'Metcalfe': [2368], 'D.D.': [2369], 'Allergy': [2371, 4050], '104:': [2375], '517-523Abstract': [2376], 'exposure': [2386], 'Jurkat': [2388], 'hTMT': [2393], 'results': [2394], 'altered': [2396], '(26.Wong': [2399], 'TMT': [2437, 2462], 'therefore': [2438], 'novel': [2443], 'granule': [2444], 'mediator': [2445], 'use': [2451], 'regulate': [2454], 'adjacent': [2455], 'types': [2457, 3671], 'they': [2459, 2571], 'contact.': [2461], 'adversely': [2464], 'affect': [2465], 'lung': [2466], 'activate': [2473], 'IL-13/IL-4Rα/STAT6-dependent': [2474], 'signaling': [2475], 'pathways.': [2476], 'It': [2477, 2626], 'discovered': [2479], 'recently': [2480], 'pro-urokinase-type': [2482], 'plasminogen': [2483], 'activator': [2484], 'preferred': [2487], '(31.Yasuda': [2493], 'FASEB': [2501], '17:': [2504], '12Google': [2505], 'potential': [2508, 4143], 'roles': [2509, 2581], 'disorders': [2520], 'prompted': [2522], 'pharmaceutical': [2524], 'industry': [2525], 'begin': [2527], 'generating': [2528], 'low': [2529], 'weight': [2531], 'inhibitors': [2533, 2547], 'before': [2534, 3698, 3722], 'number': [2536], 'deduced.': [2542], 'create': [2546], 'inactivate': [2550], 'harmful': [2552], 'dependent': [2555], 'our': [2557], 'knowledge': [2558, 2585], 'how': [2560, 2630], 'many': [2561, 2631], 'related': [2562], 'exist': [2565], 'humans,': [2567], 'expressed,': [2573], 'what': [2575], 'becomes': [2586], 'attainable,': [2587], 'generation': [2592], 'complete': [2595], 'sequence': [2596, 2979, 3006], 'transcripts.': [2603, 3052], 'To': [2604], 'deduce': [2605], 'models': [2613], 'disease,': [2616], 'it': [2617, 2654, 2670], 'imperative': [2619], 'identified.': [2625], 'presently': [2628], 'unclear': [2629], 'tryptic': [2633, 2705, 2718], 'present': [2639, 2685], 'genome.': [2643], 'Even': [2644], 'considering': [2645], '17A3.3,': [2653], 'difficult': [2656], 'assign': [2658], 'unambiguously': [2659], 'one': [2661], 'ortholog.': [2666], 'For': [2667], 'reason,': [2669], 'obvious': [2673], 'which': [2674], 'studies': [2677, 3059, 3326], 'would': [2678], 'relevant': [2680], 'humans.': [2682], 'study,': [2686], 'we': [2687, 2711, 3751], 'attempt': [2688], 'resolve': [2690], 'issues': [2692], 'comparative': [2694], 'loci': [2702], 'reside.': [2707], 'process,': [2710], 'describe': [2712], 'distinct': [2716], 'coordinately': [2723], 'We': [2727], 'establish': [2729], '17A3.3': [2738, 2771, 2982, 3010], 'orthologs.': [2741], 'systematic': [2750], 'mouse/human': [2755], 'pair': [2757], 'transgenic': [2759], 'Analysis': [2761, 4134], 'Serine': [2764], 'Protease': [2765], 'Gene': [2766], 'Cluster': [2767], 'Chromosome': [2770], 'Cloning': [2773], 'cDNAs—The': [2779], 'were': [2790, 2857, 2914, 2940, 2975, 3078, 3292, 3501, 3655, 3666, 3683, 3708, 3729, 3737, 3878, 3896, 3940, 3958, 3981, 4195], 'templates': [2793], 'search': [2795], 'novel,': [2797], 'but': [2798], 'related,': [2799], 'ESTs': [2801], 'genomic': [2803], 'bases': [2809], 'GenBank™.': [2811], 'As': [2812, 3267], 'under': [2814, 3269], '"Results,"': [2815, 3270], 'approach': [2817, 3034, 3243], '(designated': [2830], 'mMCP-11).': [2835], 'Based': [2836], 'clones,': [2845], 'entire': [2847], 'coding': [2848, 3561], 'regions': [2849], 'obtained': [2858], 'cDNA': [2860, 3041, 3566], 'from': [2862, 3184, 3855, 4174], 'BALB/c': [2863, 2874], 'skeletal': [2865], '(Clontech,': [2868], 'Palo': [2869], 'Alto,': [2870], 'CA),': [2871, 3676], 'IL-3-developed': [2873, 3271], '(mBMMCs)': [2879], '(32.Razin': [2880, 3200], 'Ihle': [2882, 3202], 'J.N.': [2883, 3203], 'Seldin': [2884, 3204], 'D.': [2885, 3205, 4047], 'Mencia-Huerta': [2886, 3206], 'Katz': [2888, 3208], 'H.R.': [2889, 3209], 'LeBlanc': [2890, 3210], 'P.A.': [2891, 3211], 'Hein': [2892, 3212], 'Caulfield': [2894, 3214], '1984;': [2902, 3222], '132:': [2903, 3223], '1479-1486PubMed': [2904, 3224], 'oligonucleotides': [2909, 3054, 3076], 'PCRs': [2913], '5′-GCAGGTGTACTATGGAGCTGGCTCTG-3′': [2915], '5′-TTAGGGTCCCAGGAGGAAGAAGGCGCTACTG-3′': [2917], 'transcript,': [2921, 2928], '5′-CAATGAGGGGTGCTTCCCACCTCCAG-3′': [2922], '5′-GAGGCTCAGGCGAGCCTGGATCCAG-3′': [2924], '5′-GATATGTGCTTGGGGATGCTCTGG-3′': [2930], '5′-AGAAAGTGAGGCTGGACCAGAAGG-3′': [2932], 'mMC-P-11': [2935], 'transcript.': [2936], 'resulting': [2938, 3065, 3956, 4193], 'products': [2939, 3067], 'purified': [2941], '1%': [2943], 'agarose': [2944], 'gels,': [2945], 'subcloned,': [2946], 'sequenced': [2948], 'confirm': [2950], 'identities.': [2952], 'mMCP-11,': [2966, 3289, 3498, 4149], 'mTMT,': [2967], 'mTessp1,': [2968, 4151], 'mDisp,': [2969, 3593], 'mBssp-4,': [2970, 4150], 'mPancreasin,': [2971, 3592], 'mIsp-1,': [2972], 'aligned': [2976], 'against': [2977], '(from': [2983], 'Genome': [2986], 'Project)': [2987], '"blastn"': [2990], 'algorithm': [2991, 3018], 'available': [2992], 'web': [2995], 'National': [2999], 'Center': [3000], 'Biotechnology': [3002], 'Information.': [3003], 'draft': [3005], 'searched': [3013], 'translated': [3016], 'tblastn': [3017], 'Spl': [3020], 'proteases.': [3029], 'Transcript': [3030], 'Analysis—A': [3031], 'semi-quantitative': [3032, 3240], 'PCR': [3033, 3066], 'screen': [3038], 'multiple': [3039], 'tissue': [3040], '(Clontech)': [3043, 3077], 'transcript': [3058, 3085], 'sizes': [3062], 'summarized': [3069], 'Table': [3071], 'Glyceraldehyde-3-phosphate': [3073], 'dehydrogenase': [3074], '(G3PDH)-specific': [3075], 'positive': [3081], 'controls': [3082], 'profiling': [3086], 'studies.': [3087], 'express': [3089, 3274], 'total': [3180], 'RNA': [3181], 'isolated': [3183], 'BALB/c,': [3185], 'C57BL/6,': [3186], '129Sv,': [3187], 'WBB6F1-W/Wv': [3189], 'mBMMCs': [3190, 3272, 3297], 'cultured': [3191, 3656, 3712, 3879], 'IL-3': [3196, 3309], '1–5': [3198], 'weeks': [3199], 'At': [3227], 'week': [3228], '3,': [3229], '>99%': [3230], 'cultures': [3236], 'MCs.': [3238, 3266], 'A': [3239], 'reverse': [3241], 'transcriptase-PCR': [3242], '(30–32': [3244], 'cycles)': [3245], 'then': [3247, 3711, 4196], 'assess': [3250], 'relative': [3252], 'levels': [3253], 'populations': [3264], 'transiently': [3273], 'mRNA.': [3276], 'investigate': [3279], 'influence': [3281], 'MC-regulatory': [3283], 'cytokines': [3284], 'experiments': [3291], 'carried': [3293], 'out': [3294], 'BALB/c-derived': [3296], 'developed': [3301, 3752, 4209], 'culturing': [3303], 'progenitors': [3304], 'combinations': [3312], 'IL-4,': [3314], 'IL-9,': [3315], 'IL-10,': [3316], 'IL-12,': [3317], 'kit': [3319, 3995], 'ligand': [3320], '(33.Gurish': [3327], 'Gillis': [3335], 'Exp.': [3340, 3395], 'Med.': [3341, 3396], '175:': [3343], '1003-1012Crossref': [3344], '(167)': [3347], '34.Ghildyal': [3350], 'Nicodemus': [3354], 'C.F.': [3355], '1993;': [3362, 3377], '151:': [3363, 3378], '3206-3214PubMed': [3364], '35.Eklund': [3367], 'K.K.': [3368], '4266-4273PubMed': [3379], '36.Ochi': [3382], 'Hirani': [3384], 'W.M.': [3385], 'Yuan': [3386], 'Q.': [3387], '190:': [3398], '267-280Crossref': [3399], '(301)': [3402], 'Whether': [3405], 'lines': [3411, 3418, 3444], '(V3': [3412], 'C1.MC/C57.1),': [3414], 'macrophage': [3416], '(RAW': [3419], 'WEHI-3),': [3421], 'hybridoma': [3425], '(BY155),': [3426], 'fibroblast': [3429], 'line': [3431], '(mTc-1)': [3432], 'mRNA': [3435], 'evaluated.': [3438], 'V3': [3440], 'C1.MC/C57.1': [3442], 'maintained': [3447], 'continuously': [3448], '>1': [3450], 'decade.': [3451], 'no': [3455], 'contaminating': [3456], 'type': [3458], 'lines.Table': [3462], 'IPrimer': [3463], 'sets': [3464], 'evaluate': [3467, 4235], 'tissuesGene/transcriptDirectionPCR': [3475], 'primersProduct': [3476], 'sizebpmT4Forward5′-CAACAGCATGTGTAACCATATG-3′503Reverse5′-GCCTGAGCAGCCCATTGCGGATC-3′mT5Forward5′-CAAGCTATTCAGCGGACGAGCACAG-3′660Reverse5′-GCTGTGCTGGCCTGGAAGCCAGTTGAG-3′mT6Forward5′-TGGGAGCACTGAGTCTGGACGTCAG-3′617Reverse5′-GTGGGATGGACCAGGAAGCTCCAG-3′mMCP-6Forward5′-CTCTTCCGGGTGCAGCTTCGTGAGCAG-3′533Reverse5′-TATGTCACCCGGGTGTAGATGCCAGG-3′mMCP-7Forward5′-ATGACCACCTGATGACTGTGAGCCAG-3′563Reverse5′-AGGAACGGAGGTCATCCTGGATGTG-3′mMCP-11Forward5′-GCTGATGAAAGTGGTCAAGATCATCCG-3′610Reverse5′-AGGAGTGAATGGATCAATATGAGTGGCTG-3′mTMTForward5′-GATCATCATGTACACTGGCTCTCCAG-3′645Reverse5′-CTACACCTCATTCAGAGTTCCGAGG-3′mBssp-4Forward5′-GTGCTGCCTCACCCCAGGTATTCTTGG-3′574Reverse5′-CAGGAGGCTGCTCATCTTCAGATCCTAG-3′mTessp1Forward5′-ACCTACAACAAGGACATCCAGCCTG-3′573Reverse5′-AGCTATCCCTACAGTATATGGACTG-3′mDispForward5′-TACCTCTGGGCAGATGCGTCTAGCG-3′607Reverse5′-GAGGATCTAGAACTCTAGAGCTCACAG-3′mPancreasinForward5′-GAAGCTGCAGCAGCCAGGACCACACG-3′677Reverse5′-CTCCCAGGGCCAGCACCATTGCATGG-3′mIsp-1Forward5′-AGGACGCCGACCCAGCCGTATACCG-3′527Reverse5′-TGATGGCAGATTGTTGCTGCAATCG-3′mIsp-2Forward5′-GCAAGGAGCTGCTGAGTGTGAGCCG-3′508Reverse5′-CAGGGCAGGAAGGACTGTACACGTGC-3′': [3477], 'Open': [3478], 'table': [3479], 'tab': [3483], 'Expression': [3484], 'Recombinant': [3486, 3731, 4006], 'Proteases': [3488], 'Mammalian': [3490], 'Insect': [3492, 3800], 'Cells—Bioengineered': [3493], 'forms': [3494], 'generated': [3502, 3738], 'contained': [3507, 3613], 'His6': [3509], 'V5': [3511], '(Gly-Lys-Pro-Ile-Pro-Asn-Pro-Leu-Leu-Gly-Leu-Asp-Ser-Thr)': [3512], 'peptides': [3513], 'termini,': [3517], 'previously': [3520, 3753], 'instance,': [3559, 3936], 'vector': [3573], 'pcDNA3.1/V5-His': [3574], 'TOPO': [3575], '(Invitrogen).': [3576], 'Vector': [3577], 'lacking': [3578], 'an': [3579, 3860], 'insert': [3580], 'served': [3581], 'negative': [3584], 'control': [3585], 'transfection': [3588], 'experiments.': [3589], 'predicted': [3597, 4137], 'glycosylphosphatidylinositol': [3598], '(GPI)': [3599], 'signal': [3600], 'termini.': [3605], 'instances,': [3609], '8-mer': [3615], 'FLAG': [3616, 3819, 3845], '(Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys)': [3617], 'inbetween': [3619, 3823], 'propeptide': [3621, 3810, 3826], 'mature': [3624], 'protease.': [3628, 3933], 'African': [3629], 'green': [3630], 'monkey': [3631], 'SV40-transformed': [3632], 'kidney': [3633, 3648], 'COS-7': [3634], '(line': [3636, 3652], 'CRL-1651;': [3637], 'American': [3638], 'Type': [3639], 'Culture': [3640], 'Collection': [3641], '(ATCC),': [3642], 'Manassas,': [3643], 'VA)': [3644], 'embryonic': [3647], 'HEK': [3649], '293T': [3650], 'CRL-1573;': [3653], 'ATCC)': [3654], 'DMEM': [3658], 'containing': [3659, 3904, 3944], '10%': [3660], 'fetal': [3661], 'calf': [3662], 'serum.': [3663], 'Transient': [3664], 'transfections': [3665], 'performed': [3667], 'SuperFect': [3673], '(Qiagen,': [3674], 'Valencia,': [3675], 'according': [3677, 4186], "manufacturer's": [3680, 4189], 'instructions.': [3681], 'Cells': [3682], 'plated': [3684], 'density': [3687], '∼2': [3689], '×': [3690], '105': [3691], 'cells/well': [3692], '6-well': [3694], 'plates': [3695], '24': [3696, 3720], 'h': [3697, 3702, 3721], 'transfection.': [3699], 'Twenty': [3700], 'four': [3701], 'after': [3703], 'transfection,': [3704], 'treated': [3706], 'washed': [3709, 3913], 'serum-free': [3714], 'Opti-MEM': [3715], 'I': [3716], 'medium': [3717, 3725, 3858, 3886, 3895, 4170], 'another': [3719], 'conditioned': [3724, 3857, 3894, 4169], 'pellets': [3728], 'collected.': [3730], 'High': [3740], 'Five': [3741], 'modification': [3746], 'system': [3750], 'generate': [3755], 'βII,': [3796], 'ϵ.': [3799], 'lack': [3802], 'post-translational': [3804], 'machinery': [3805], 'needed': [3806], 'remove': [3808], 'zymogen.': [3816], 'natural': [3825], 'first': [3828], 'residue': [3829], 'catalytic': [3832], 'allow': [3835], 'activation': [3836], 'bioengineered': [3840], 'zymogen': [3841], 'enterokinase.': [3843], 'facilitates': [3848], 'purification': [3850], 'immunoaffinity': [3861], 'column.': [3862], 'system,': [3866], 'C-terminal': [3868], 'hydrophobic': [3869], 'removed.': [3874], 'Protease-expressing': [3875], 'room': [3881], 'temperature': [3882], 'serum-free,': [3884], 'X-press': [3885], '6–7': [3888], 'days.': [3889], 'Generally,': [3890], '750': [3891], 'ml': [3892, 3916], 'loaded': [3897], 'onto': [3898], 'freshly': [3900], 'prepared': [3901], '1-ml': [3902, 3938], 'column': [3903, 3911], 'anti-FLAG': [3905, 3975], 'M2': [3906, 3976], 'antibody': [3907, 3977], '(Sigma).': [3908, 3978], 'After': [3909], '250': [3915], 'Tris-buffered': [3918], 'saline': [3919], '(pH': [3920, 3925, 3951], '7.0),': [3921], '0.1': [3922], 'm': [3923, 3949], 'glycine': [3924], '3.5)': [3926], 'elute': [3930], 'bound': [3932], 'fractions': [3939, 3957, 3980], 'collected': [3941], 'tubes': [3943], '20': [3945], 'μl': [3946], 'Tris-HCl': [3950], '8.0).': [3952], 'Samples': [3953], 'analyzed': [3959], 'SDS-PAGE': [3961], 'Coomassie': [3966], 'Blue-stained': [3967], 'immunoreactive': [3971], 'Protease-enriched': [3979], 'pooled': [3982], 'protein': [3985, 3992], 'contents': [3986], 'estimated': [3987], 'micro': [3990], 'BCA': [3991], 'assay': [3993, 4208], 'reagent': [3994], '(Pierce).': [3996], 'Evaluation': [3997], 'Glycosylation': [4000], 'Status': [4001], 'Substrate': [4003], 'Specificities': [4004], 'Proteases—Many': [4008], 'N-linked': [4014, 4144, 4163], 'glycans': [4015, 4091], '(37.Cromlish': [4016], 'Seidah': [4018], 'N.G.': [4019], 'Marcinkiewicz': [4020], 'Hamelin': [4022], 'Johnson': [4024], 'D.A.': [4025], 'Chretien': [4026], '1987;': [4031], '262:': [4032], '1363-1373Abstract': [4033], '38.Benyon': [4040], 'R.C.': [4041], 'Imai': [4042], 'Abe': [4044], 'Befus': [4046], 'Int.': [4048], 'Arch.': [4049], 'Appl.': [4051], '94:': [4054], '218-219Crossref': [4055], '(8)': [4058], '39.Ghildyal': [4061], 'Freelund': [4065], '1994;': [4077], '153:': [4078], '2624-2630PubMed': [4079], 'expression/site-directed': [4083], 'mutagenesis': [4084], 'revealed': [4088, 4142], 'often': [4092], 'important': [4094], 'thermal': [4096], 'stability': [4097], '(40.Huang': [4098], 'Vagi': [4102], 'Ferrazzi': [4106], 'Burklow': [4108], '275:': [4122], '351-358Abstract': [4123], 'primary': [4138], 'glycosylation': [4145], 'sites': [4146], 'mPancreasin.': [4153], 'determine': [4156], 'whether': [4157, 4236], 'glycans,': [4164], 'sample': [4166], 'lysate': [4173], 'transfectant': [4176], 'incubated': [4178], 'PNGaseF': [4180], '(New': [4181], 'England': [4182], 'Biolabs,': [4183], 'Beverly,': [4184], 'MA)': [4185], 'suggested': [4190], 'conditions.': [4191], 'digests': [4194], 'subjected': [4197], 'SDS-PAGE/immunoblot': [4199], 'analysis.': [4200], 'biotinylated': [4202], 'ketone': [4205], '(PPACK)': [4206], 'active-site': [4207], 'Williams': [4211], '(41.Williams': [4214], 'E.B.': [4215], 'Krishnaswamy': [4216], 'Mann': [4218], 'K.G.': [4219], '264:': [4224], '7536-7545Abstract': [4225], 'uncharacterized': [4241]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2111885508', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2025-01-06T11:04:42.532072', 'created_date': '2016-06-24'}