Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2111004292', 'doi': 'https://doi.org/10.1212/wnl.56.10.1265', 'title': 'Inborn errors of metabolism', 'display_name': 'Inborn errors of metabolism', 'publication_year': 2001, 'publication_date': '2001-05-22', 'ids': {'openalex': 'https://openalex.org/W2111004292', 'doi': 'https://doi.org/10.1212/wnl.56.10.1265', 'mag': '2111004292', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11383558'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.56.10.1265', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073931643', 'display_name': 'Andreea Nissenkorn', 'orcid': 'https://orcid.org/0000-0001-8642-5648'}, 'institutions': [{'id': 'https://openalex.org/I2800717019', 'display_name': 'Wolfson Medical Center', 'ror': 'https://ror.org/04ayype77', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800717019']}, {'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Andreea Nissenkorn', 'raw_affiliation_strings': ['From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.'], 'affiliations': [{'raw_affiliation_string': 'From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.', 'institution_ids': ['https://openalex.org/I2800717019', 'https://openalex.org/I2799810450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016149959', 'display_name': 'Marina Michelson', 'orcid': 'https://orcid.org/0000-0002-3794-0843'}, 'institutions': [{'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}, {'id': 'https://openalex.org/I2800717019', 'display_name': 'Wolfson Medical Center', 'ror': 'https://ror.org/04ayype77', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800717019']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Marina Michelson', 'raw_affiliation_strings': ['From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.'], 'affiliations': [{'raw_affiliation_string': 'From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.', 'institution_ids': ['https://openalex.org/I2799810450', 'https://openalex.org/I2800717019']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048611020', 'display_name': 'Bruria Ben‐Zeev', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800717019', 'display_name': 'Wolfson Medical Center', 'ror': 'https://ror.org/04ayype77', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800717019']}, {'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Bruria Ben-Zeev', 'raw_affiliation_strings': ['From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.'], 'affiliations': [{'raw_affiliation_string': 'From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.', 'institution_ids': ['https://openalex.org/I2800717019', 'https://openalex.org/I2799810450']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068825956', 'display_name': 'Tally Lerman‐Sagie', 'orcid': 'https://orcid.org/0000-0001-6641-6875'}, 'institutions': [{'id': 'https://openalex.org/I2800717019', 'display_name': 'Wolfson Medical Center', 'ror': 'https://ror.org/04ayype77', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800717019']}, {'id': 'https://openalex.org/I2799810450', 'display_name': 'Sheba Medical Center', 'ror': 'https://ror.org/020rzx487', 'country_code': 'IL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799810450']}], 'countries': ['IL'], 'is_corresponding': False, 'raw_author_name': 'Tally Lerman–Sagie', 'raw_affiliation_strings': ['From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.'], 'affiliations': [{'raw_affiliation_string': 'From the Pediatric Metabolic–Neurogenetic Unit (Drs. Nissenkorn, Michelson, and Lerman–Sagie), Wolfson Medical Center, Holon; and the Pediatric Neurology Unit (B. Ben-Zeev), Sheba Medical Center, Israel.', 'institution_ids': ['https://openalex.org/I2800717019', 'https://openalex.org/I2799810450']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.518, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 127, 'citation_normalized_percentile': {'value': 0.699346, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '56', 'issue': '10', 'first_page': '1265', 'last_page': '1272'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolic Disorders and Biochemical Genetics', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11027', 'display_name': 'Metabolic Disorders and Biochemical Genetics', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11072', 'display_name': 'Peroxisome Proliferator-Activated Receptors', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/inborn-errors-of-metabolism', 'display_name': 'Inborn Errors of Metabolism', 'score': 0.648636}, {'id': 'https://openalex.org/keywords/hyperglycinemia', 'display_name': 'Hyperglycinemia', 'score': 0.6202169}, {'id': 'https://openalex.org/keywords/dysgenesis', 'display_name': 'Dysgenesis', 'score': 0.552386}, {'id': 'https://openalex.org/keywords/metabolism', 'display_name': 'Metabolism', 'score': 0.548426}, {'id': 'https://openalex.org/keywords/hyperammonemia', 'display_name': 'Hyperammonemia', 'score': 0.4473719}, {'id': 'https://openalex.org/keywords/metabolic-disorder', 'display_name': 'Metabolic disorder', 'score': 0.4243505}], 'concepts': [{'id': 'https://openalex.org/C2779646400', 'wikidata': 'https://www.wikidata.org/wiki/Q1758393', 'display_name': 'Inborn error of metabolism', 'level': 2, 'score': 0.63254}, {'id': 'https://openalex.org/C2781185993', 'wikidata': 'https://www.wikidata.org/wiki/Q5958026', 'display_name': 'Hyperglycinemia', 'level': 4, 'score': 0.6202169}, {'id': 'https://openalex.org/C2779812711', 'wikidata': 'https://www.wikidata.org/wiki/Q5319415', 'display_name': 'Dysgenesis', 'level': 2, 'score': 0.552386}, {'id': 'https://openalex.org/C2781374659', 'wikidata': 'https://www.wikidata.org/wiki/Q1459821', 'display_name': 'Holoprosencephaly', 'level': 4, 'score': 0.46610793}, {'id': 'https://openalex.org/C2778183499', 'wikidata': 'https://www.wikidata.org/wiki/Q223851', 'display_name': 'Corpus callosum', 'level': 2, 'score': 0.45926917}, {'id': 'https://openalex.org/C2781099255', 'wikidata': 'https://www.wikidata.org/wiki/Q1640868', 'display_name': 'Hyperammonemia', 'level': 2, 'score': 0.4473719}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.4366535}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4292941}, {'id': 'https://openalex.org/C2777735490', 'wikidata': 'https://www.wikidata.org/wiki/Q2351083', 'display_name': 'Metabolic disorder', 'level': 2, 'score': 0.4243505}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3970447}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3773074}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.24680945}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.22036457}, {'id': 'https://openalex.org/C172680121', 'wikidata': 'https://www.wikidata.org/wiki/Q26513', 'display_name': 'Fetus', 'level': 3, 'score': 0.20206961}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.1699931}, {'id': 'https://openalex.org/C2777756961', 'wikidata': 'https://www.wikidata.org/wiki/Q620730', 'display_name': 'Glycine', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000002', 'qualifier_name': 'abnormalities', 'is_major_topic': True}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D020739', 'descriptor_name': 'Brain Diseases, Metabolic, Inborn', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D009421', 'descriptor_name': 'Nervous System Malformations', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D020739', 'descriptor_name': 'Brain Diseases, Metabolic, Inborn', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D020739', 'descriptor_name': 'Brain Diseases, Metabolic, Inborn', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020739', 'descriptor_name': 'Brain Diseases, Metabolic, Inborn', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002465', 'descriptor_name': 'Cell Movement', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007231', 'descriptor_name': 'Infant, Newborn', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009421', 'descriptor_name': 'Nervous System Malformations', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009421', 'descriptor_name': 'Nervous System Malformations', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009421', 'descriptor_name': 'Nervous System Malformations', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1212/wnl.56.10.1265', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S79704628', 'display_name': 'Neurology', 'issn_l': '0028-3878', 'issn': ['0028-3878', '1526-632X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11383558', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 62, 'referenced_works': ['https://openalex.org/W1501288544', 'https://openalex.org/W1878769090', 'https://openalex.org/W1882812558', 'https://openalex.org/W1921739958', 'https://openalex.org/W1950035178', 'https://openalex.org/W1964010956', 'https://openalex.org/W1964040699', 'https://openalex.org/W1964390696', 'https://openalex.org/W1969336236', 'https://openalex.org/W1972336140', 'https://openalex.org/W1974396232', 'https://openalex.org/W1975282762', 'https://openalex.org/W1976551834', 'https://openalex.org/W1976773936', 'https://openalex.org/W1982931331', 'https://openalex.org/W1984563448', 'https://openalex.org/W1984907362', 'https://openalex.org/W1985670840', 'https://openalex.org/W1992409950', 'https://openalex.org/W1994466198', 'https://openalex.org/W1997197920', 'https://openalex.org/W1997685540', 'https://openalex.org/W2000572318', 'https://openalex.org/W2002249795', 'https://openalex.org/W2003873905', 'https://openalex.org/W2006449813', 'https://openalex.org/W2013462294', 'https://openalex.org/W2017853893', 'https://openalex.org/W2021515431', 'https://openalex.org/W2021640057', 'https://openalex.org/W2022414521', 'https://openalex.org/W2029821385', 'https://openalex.org/W2031551849', 'https://openalex.org/W2041596182', 'https://openalex.org/W2042047528', 'https://openalex.org/W2044189228', 'https://openalex.org/W2049207948', 'https://openalex.org/W2051460160', 'https://openalex.org/W2056156479', 'https://openalex.org/W2059614045', 'https://openalex.org/W2059744028', 'https://openalex.org/W2060840571', 'https://openalex.org/W2062297025', 'https://openalex.org/W2062615022', 'https://openalex.org/W2067694197', 'https://openalex.org/W2069326021', 'https://openalex.org/W2072715269', 'https://openalex.org/W2087222898', 'https://openalex.org/W2092621912', 'https://openalex.org/W2104533775', 'https://openalex.org/W2110801042', 'https://openalex.org/W2138229358', 'https://openalex.org/W2141503793', 'https://openalex.org/W2144062723', 'https://openalex.org/W2156679744', 'https://openalex.org/W2158431193', 'https://openalex.org/W2158507590', 'https://openalex.org/W2316751316', 'https://openalex.org/W2318537264', 'https://openalex.org/W2406721117', 'https://openalex.org/W2413838754', 'https://openalex.org/W3038061955'], 'related_works': ['https://openalex.org/W62748397', 'https://openalex.org/W56499974', 'https://openalex.org/W2990594715', 'https://openalex.org/W2441946681', 'https://openalex.org/W2395946926', 'https://openalex.org/W2103555897', 'https://openalex.org/W2014198765', 'https://openalex.org/W2012702007', 'https://openalex.org/W1992399557', 'https://openalex.org/W1989651286'], 'abstract_inverted_index': {'Brain': [0], 'malformations': [1], 'are': [2], 'caused': [3], 'by': [4, 13], 'a': [5, 77, 115, 144], 'disruption': [6], 'in': [7, 38, 92, 108, 170], 'the': [8, 21, 45, 123, 132, 148, 151, 158, 161], 'sequence': [9], 'of': [10, 26, 54, 83, 111, 114, 122, 127, 131, 135, 143, 150, 160], 'normal': [11, 133], 'development': [12, 107], 'various': [14], 'environmental': [15], 'or': [16, 117, 129], 'genetic': [17, 165], 'factors.': [18], 'By': [19], 'modifying': [20], 'intrauterine': [22, 119, 136], 'milieu,': [23, 120], 'inborn': [24, 52, 109], 'errors': [25, 53, 110], 'metabolism': [27, 82, 94], 'may': [28, 95], 'cause': [29, 76, 149], 'brain': [30, 48, 106, 152], 'dysgenesis.': [31], 'However,': [32], 'this': [33], 'association': [34], 'is': [35], 'typically': [36], 'described': [37], 'single': [39], 'case': [40], 'reports.': [41], 'The': [42, 141], 'authors': [43], 'review': [44], 'relationship': [46], 'between': [47], 'dysgenesis': [49], 'and': [50, 58, 72, 125, 163], 'specific': [51], 'metabolism.': [55], 'Peroxisomal': [56], 'disorders': [57], 'fatty': [59], 'acid': [60, 85], 'oxidation': [61], 'defects': [62, 91], 'can': [63], 'produce': [64, 96], 'migration': [65], 'defects.': [66], 'Pyruvate': [67], 'dehydrogenase': [68], 'deficiency,': [69], 'nonketotic': [70], 'hyperglycinemia,': [71], 'maternal': [73], 'phenylketonuria': [74], 'preferentially': [75], 'dysgenetic': [78], 'corpus': [79], 'callosum.': [80], 'Abnormal': [81], 'folic': [84], 'causes': [86], 'neural': [87], 'tube': [88], 'defects,': [89], 'whereas': [90], 'cholesterol': [93], 'holoprosencephaly.': [97], 'Various': [98], 'mechanisms': [99], 'have': [100], 'been': [101], 'proposed': [102], 'to': [103, 167], 'explain': [104], 'abnormal': [105], 'metabolism:': [112], 'production': [113], 'toxic': [116], 'energy-deficient': [118], 'modification': [121], 'content': [124], 'function': [126], 'membranes,': [128], 'disturbance': [130], 'expression': [134], 'genes': [137], 'responsible': [138], 'for': [139, 156, 164], 'morphogenesis.': [140], 'recognition': [142], 'metabolic': [145], 'disorder': [146], 'as': [147], 'malformation': [153], 'has': [154], 'implications': [155], 'both': [157], 'care': [159], 'patient': [162], 'counseling': [166], 'prevent': [168], 'recurrence': [169], 'subsequent': [171], 'pregnancies.': [172]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2111004292', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-08-28T14:25:53.010235', 'created_date': '2016-06-24'}