Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2110962567', 'doi': 'https://doi.org/10.1111/j.1440-0960.2012.00968.x', 'title': 'Associations between aberrant <scp>DNA</scp> methylation and transcript levels of <scp>DNMT1</scp> and <scp>MBD2</scp> in <scp>CD4+T</scp> cells from patients with systemic lupus erythematosus', 'display_name': 'Associations between aberrant <scp>DNA</scp> methylation and transcript levels of <scp>DNMT1</scp> and <scp>MBD2</scp> in <scp>CD4+T</scp> cells from patients with systemic lupus erythematosus', 'publication_year': 2012, 'publication_date': '2012-11-06', 'ids': {'openalex': 'https://openalex.org/W2110962567', 'doi': 'https://doi.org/10.1111/j.1440-0960.2012.00968.x', 'mag': '2110962567', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23127209'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1440-0960.2012.00968.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S140888521', 'display_name': 'Australasian Journal of Dermatology', 'issn_l': '0004-8380', 'issn': ['0004-8380', '1440-0960'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000608768', 'display_name': 'Haihong Qin', 'orcid': 'https://orcid.org/0009-0005-4195-8172'}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hai‐Hong Qin', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102146326', 'display_name': 'Xiao‐Hua Zhu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao‐Hua Zhu', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100754778', 'display_name': 'Jun Liang', 'orcid': 'https://orcid.org/0000-0001-5318-4323'}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jun Liang', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049663405', 'display_name': 'Yongsheng Yang', 'orcid': 'https://orcid.org/0000-0001-6997-4530'}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yong‐Sheng Yang', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101648785', 'display_name': 'Shangshang Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shang‐Shang Wang', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101632434', 'display_name': 'Weimin Shi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210135742', 'display_name': "Shanghai First People's Hospital", 'ror': 'https://ror.org/04a46mh28', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210135742']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei‐Min Shi', 'raw_affiliation_strings': ["The First People's Hospital, Jiaotong University, Shanghai, China"], 'affiliations': [{'raw_affiliation_string': "The First People's Hospital, Jiaotong University, Shanghai, China", 'institution_ids': ['https://openalex.org/I4210135742']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5102094301', 'display_name': 'Jin‐Hua Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210159575', 'display_name': 'Huashan Hospital', 'ror': 'https://ror.org/05201qm87', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210159575']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jin‐Hua Xu', 'raw_affiliation_strings': ['Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.', 'institution_ids': ['https://openalex.org/I4210159575', 'https://openalex.org/I24943067']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3810, 'currency': 'USD', 'value_usd': 3810, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.663, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.836376, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '54', 'issue': '2', 'first_page': '90', 'last_page': '95'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10308', 'display_name': 'Systemic Lupus Erythematosus Research', 'score': 0.9919, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9916, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dnmt1', 'display_name': 'DNMT1', 'score': 0.8641791}, {'id': 'https://openalex.org/keywords/dna-methyltransferase', 'display_name': 'DNA methyltransferase', 'score': 0.6971118}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.60095334}], 'concepts': [{'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.9051429}, {'id': 'https://openalex.org/C175211621', 'wikidata': 'https://www.wikidata.org/wiki/Q14907998', 'display_name': 'DNMT1', 'level': 5, 'score': 0.8641791}, {'id': 'https://openalex.org/C2779979206', 'wikidata': 'https://www.wikidata.org/wiki/Q1154602', 'display_name': 'DNA methyltransferase', 'level': 5, 'score': 0.6971118}, {'id': 'https://openalex.org/C33288867', 'wikidata': 'https://www.wikidata.org/wiki/Q518328', 'display_name': 'Methylation', 'level': 3, 'score': 0.67172486}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.60095334}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.47462952}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.46449068}, {'id': 'https://openalex.org/C48023723', 'wikidata': 'https://www.wikidata.org/wiki/Q856198', 'display_name': 'Real-time polymerase chain reaction', 'level': 3, 'score': 0.4633449}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.45026094}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.42071697}, {'id': 'https://openalex.org/C91965660', 'wikidata': 'https://www.wikidata.org/wiki/Q415875', 'display_name': 'Methyltransferase', 'level': 4, 'score': 0.42045924}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.38430497}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3693109}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.33728006}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.29885694}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.13988873}], 'mesh': [{'descriptor_ui': 'D004248', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016022', 'descriptor_name': 'Case-Control Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000076123', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004248', 'descriptor_name': 'DNA (Cytosine-5-)-Methyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008180', 'descriptor_name': 'Lupus Erythematosus, Systemic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1440-0960.2012.00968.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S140888521', 'display_name': 'Australasian Journal of Dermatology', 'issn_l': '0004-8380', 'issn': ['0004-8380', '1440-0960'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23127209', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 22, 'referenced_works': ['https://openalex.org/W1538430276', 'https://openalex.org/W1605104953', 'https://openalex.org/W1637312052', 'https://openalex.org/W1823692109', 'https://openalex.org/W1963746213', 'https://openalex.org/W1968679842', 'https://openalex.org/W1994009027', 'https://openalex.org/W2008261028', 'https://openalex.org/W2011496738', 'https://openalex.org/W2020699105', 'https://openalex.org/W2022081039', 'https://openalex.org/W2024073989', 'https://openalex.org/W2028418054', 'https://openalex.org/W2042515987', 'https://openalex.org/W2047396455', 'https://openalex.org/W2070527591', 'https://openalex.org/W2080040722', 'https://openalex.org/W2084747376', 'https://openalex.org/W2092550414', 'https://openalex.org/W2098976753', 'https://openalex.org/W2123095447', 'https://openalex.org/W2150606117'], 'related_works': ['https://openalex.org/W3149210626', 'https://openalex.org/W2465225217', 'https://openalex.org/W2368628704', 'https://openalex.org/W2326246873', 'https://openalex.org/W2143007402', 'https://openalex.org/W2079709058', 'https://openalex.org/W2018283920', 'https://openalex.org/W2015134259', 'https://openalex.org/W1987527321', 'https://openalex.org/W1521916652'], 'abstract_inverted_index': {'Abstract': [0], 'Background/Objectives': [1], 'It': [2], 'seems': [3], 'that': [4, 148], 'global': [5, 76, 113, 121, 173, 210, 242], 'DNA': [6, 33, 42, 49, 77, 88, 114, 122, 174, 211, 215], 'hypomethylation': [7, 216, 243], 'in': [8, 55, 80, 141, 181, 188, 222, 245, 248], 'CD4+T': [9, 56, 62, 81, 246], 'cells': [10, 57, 63, 82, 247], 'is': [11], 'linked': [12], 'to': [13], 'the': [14, 24, 39, 86, 120, 128, 223, 241], 'pathogenesis': [15, 224], 'of': [16, 48, 58, 95, 139, 149, 179, 225, 231, 240], 'systemic': [17], 'lupus': [18], 'erythematosus': [19], '(': [20, 51, 133], 'SLE': [21, 29, 59, 70, 108, 129, 142, 182, 226, 249], ').': [22, 135], 'However,': [23], 'underlying': [25], 'mechanism': [26], 'by': [27, 85, 101], 'which': [28], 'patients': [30, 68, 109, 143, 183], 'show': [31], 'hypomethylated': [32], 'remains': [34], 'unclear.': [35], 'This': [36], 'study': [37], 'explored': [38], 'relationship': [40], 'between': [41, 156, 168, 195, 205], 'methylation': [43, 78, 89, 115, 123], 'patterns': [44], 'and': [45, 53, 71, 97, 119, 151, 160, 172, 190, 199, 201, 209, 233], 'expression': [46, 229], 'levels': [47, 79, 94, 116, 138, 159, 171, 178, 198, 208, 230], 'methyltransferases': [50], 'DNMT1)': [52], 'MBD2': [54, 98, 180, 196, 206, 234], 'patients.': [60], 'Methods': [61], 'were': [64, 83, 99, 144, 184], 'obtained': [65], 'from': [66], '30': [67], 'with': [69, 127], '18': [72], 'normal': [73], 'controls.': [74], 'The': [75, 92, 136, 176], 'evaluated': [84], 'Methyflash': [87], 'quantification': [90], 'kit.': [91], 'mRNA': [93, 137, 158, 170, 177, 197, 207, 235], 'DNMT1': [96, 140, 157, 169, 232], 'quantified': [100], 'quantitative': [102], 'real‐time': [103], 'polymerase': [104], 'chain': [105], 'reaction.': [106], 'Results': [107], 'had': [110], 'significantly': [111, 145, 185], 'lower': [112, 146], 'than': [117, 147, 187], 'controls,': [118, 189], 'was': [124, 153, 164, 192], 'inversely': [125], 'correlated': [126], 'disease': [130], 'activity': [131], 'index': [132], 'SLEDAI': [134, 161, 200], 'controls': [150], 'there': [152, 163, 191], 'no': [154], 'correlation': [155, 167, 194, 204], 'but': [162], 'a': [165, 219], 'positive': [166, 193], 'methylation.': [175, 212], 'higher': [186], 'an': [202], 'inverse': [203], 'Conclusions': [213], 'Global': [214], 'may': [217, 236], 'play': [218], 'pivotal': [220], 'role': [221], '.': [227, 250], 'Abnormal': [228], 'be': [237], 'important': [238], 'causes': [239], 'observed': [244]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2110962567', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-24T14:12:01.037206', 'created_date': '2016-06-24'}