Title: Canakinumab for treatment of cryopyrin-associated periodic syndrome
Abstract:Importance of the field: Autoinflammatory syndromes such as cryopyrin-associated periodic syndromes (CAPS) place a heavy burden on affected individuals as well as on their families due to significant ...Importance of the field: Autoinflammatory syndromes such as cryopyrin-associated periodic syndromes (CAPS) place a heavy burden on affected individuals as well as on their families due to significant morbidity and increased mortality. The inflammatory response in CAPS is caused by an overwhelming activation of the pro-inflammatory cytokine IL-1, which was identified as a promising treatment target.Read More
Publication Year: 2010
Publication Date: 2010-10-19
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 15
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Title: $Canakinumab for treatment of cryopyrin-associated periodic syndrome
Abstract: Importance of the field: Autoinflammatory syndromes such as cryopyrin-associated periodic syndromes (CAPS) place a heavy burden on affected individuals as well as on their families due to significant morbidity and increased mortality. The inflammatory response in CAPS is caused by an overwhelming activation of the pro-inflammatory cytokine IL-1, which was identified as a promising treatment target.