Publication Information

{'id': 'https://openalex.org/W2109825947', 'doi': 'https://doi.org/10.1093/genetics/116.4.565', 'title': 'Analysis of the Promoter of the <i>ninaE</i> Opsin Gene in <i>Drosophila melanogaster</i>', 'display_name': 'Analysis of the Promoter of the <i>ninaE</i> Opsin Gene in <i>Drosophila melanogaster</i>', 'publication_year': 1987, 'publication_date': '1987-08-01', 'ids': {'openalex': 'https://openalex.org/W2109825947', 'doi': 'https://doi.org/10.1093/genetics/116.4.565', 'mag': '2109825947', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3040524', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1203488'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/genetics/116.4.565', 'pdf_url': 'https://academic.oup.com/genetics/article-pdf/116/4/565/34453297/genetics0565.pdf', 'source': {'id': 'https://openalex.org/S65932378', 'display_name': 'Genetics', 'issn_l': '0016-6731', 'issn': ['0016-6731', '1943-2631'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/genetics/article-pdf/116/4/565/34453297/genetics0565.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015648208', 'display_name': 'Drzislav Mismer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Drzislav Mismer', 'raw_affiliation_strings': ['Department of Biochemistry, University of California, Berkeley, California 94720'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of California, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086255792', 'display_name': 'Gerald M. Rubin', 'orcid': 'https://orcid.org/0000-0001-8762-8703'}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gerald M Rubin', 'raw_affiliation_strings': ['Department of Biochemistry, University of California, Berkeley, California 94720'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of California, Berkeley, California 94720', 'institution_ids': ['https://openalex.org/I95457486']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4264, 'currency': 'USD', 'value_usd': 4264, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.64, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 230, 'citation_normalized_percentile': {'value': 0.943085, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '116', 'issue': '4', 'first_page': '565', 'last_page': '578'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12236', 'display_name': 'Optogenetics in Neuroscience and Biophysics Research', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12236', 'display_name': 'Optogenetics in Neuroscience and Biophysics Research', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10691', 'display_name': 'Molecular Mechanisms of Retinal Degeneration and Regeneration', 'score': 0.9955, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12929', 'display_name': 'Transgenic Animal Research', 'score': 0.9899, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/opsin', 'display_name': 'Opsin', 'score': 0.6030573}, {'id': 'https://openalex.org/keywords/sensory-rhodopsin', 'display_name': 'Sensory Rhodopsin', 'score': 0.469347}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8664423}, {'id': 'https://openalex.org/C2780104201', 'wikidata': 'https://www.wikidata.org/wiki/Q130888', 'display_name': 'Drosophila melanogaster', 'level': 3, 'score': 0.86201704}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.7625484}, {'id': 'https://openalex.org/C2776041557', 'wikidata': 'https://www.wikidata.org/wiki/Q3715451', 'display_name': 'Drosophila (subgenus)', 'level': 3, 'score': 0.6060293}, {'id': 'https://openalex.org/C30028475', 'wikidata': 'https://www.wikidata.org/wiki/Q24785022', 'display_name': 'Opsin', 'level': 4, 'score': 0.6030573}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.5993908}, {'id': 'https://openalex.org/C78458016', 'wikidata': 'https://www.wikidata.org/wiki/Q840400', 'display_name': 'Evolutionary biology', 'level': 1, 'score': 0.3637279}, {'id': 'https://openalex.org/C202033177', 'wikidata': 'https://www.wikidata.org/wiki/Q423107', 'display_name': 'Rhodopsin', 'level': 3, 'score': 0.08559507}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.05616206}, {'id': 'https://openalex.org/C2780827179', 'wikidata': 'https://www.wikidata.org/wiki/Q422001', 'display_name': 'Retinal', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D005136', 'descriptor_name': 'Eye Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D005796', 'descriptor_name': 'Genes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000123', 'descriptor_name': 'Acetyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015500', 'descriptor_name': 'Chloramphenicol O-Acetyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004262', 'descriptor_name': 'DNA Restriction Enzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005136', 'descriptor_name': 'Eye Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005809', 'descriptor_name': 'Genes, Regulator', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009693', 'descriptor_name': 'Nucleic Acid Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017299', 'descriptor_name': 'Rod Opsins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/genetics/116.4.565', 'pdf_url': 'https://academic.oup.com/genetics/article-pdf/116/4/565/34453297/genetics0565.pdf', 'source': {'id': 'https://openalex.org/S65932378', 'display_name': 'Genetics', 'issn_l': '0016-6731', 'issn': ['0016-6731', '1943-2631'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1203169', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3040524', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/genetics/116.4.565', 'pdf_url': 'https://academic.oup.com/genetics/article-pdf/116/4/565/34453297/genetics0565.pdf', 'source': {'id': 'https://openalex.org/S65932378', 'display_name': 'Genetics', 'issn_l': '0016-6731', 'issn': ['0016-6731', '1943-2631'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 54, 'referenced_works': ['https://openalex.org/W1274000131', 'https://openalex.org/W137437809', 'https://openalex.org/W146513923', 'https://openalex.org/W1595948784', 'https://openalex.org/W1664219507', 'https://openalex.org/W187222491', 'https://openalex.org/W1966152350', 'https://openalex.org/W1984042761', 'https://openalex.org/W1993762986', 'https://openalex.org/W1999552046', 'https://openalex.org/W2004811543', 'https://openalex.org/W2006842412', 'https://openalex.org/W2008936546', 'https://openalex.org/W2009993853', 'https://openalex.org/W2018184392', 'https://openalex.org/W2019875735', 'https://openalex.org/W2022760892', 'https://openalex.org/W2025060557', 'https://openalex.org/W2026042821', 'https://openalex.org/W2036639970', 'https://openalex.org/W2036690337', 'https://openalex.org/W2038218774', 'https://openalex.org/W2043093709', 'https://openalex.org/W2055778129', 'https://openalex.org/W2056505927', 'https://openalex.org/W2057893650', 'https://openalex.org/W2063985696', 'https://openalex.org/W2064636012', 'https://openalex.org/W2069960659', 'https://openalex.org/W2077656499', 'https://openalex.org/W2080038265', 'https://openalex.org/W2080567269', 'https://openalex.org/W2086650594', 'https://openalex.org/W2091228527', 'https://openalex.org/W2093817390', 'https://openalex.org/W2114832888', 'https://openalex.org/W2123491438', 'https://openalex.org/W2124090088', 'https://openalex.org/W2124923401', 'https://openalex.org/W2136008370', 'https://openalex.org/W2138270253', 'https://openalex.org/W2142526109', 'https://openalex.org/W2144206181', 'https://openalex.org/W2144634347', 'https://openalex.org/W2157724269', 'https://openalex.org/W2319020379', 'https://openalex.org/W2420204813', 'https://openalex.org/W242681993', 'https://openalex.org/W2921269466', 'https://openalex.org/W322886742', 'https://openalex.org/W4243695823', 'https://openalex.org/W48131157', 'https://openalex.org/W60725364', 'https://openalex.org/W983151938'], 'related_works': ['https://openalex.org/W4400352626', 'https://openalex.org/W4390801875', 'https://openalex.org/W4323037479', 'https://openalex.org/W4311607074', 'https://openalex.org/W3166827729', 'https://openalex.org/W3025486376', 'https://openalex.org/W2753303236', 'https://openalex.org/W2236776555', 'https://openalex.org/W2082613811', 'https://openalex.org/W162000807'], 'abstract_inverted_index': {'We': [0, 128], 'have': [1, 129], 'analyzed': [2], 'the': [3, 8, 14, 19, 23, 31, 37, 43, 50, 62, 70, 79, 85, 90, 104, 108, 113, 118, 136, 143, 182, 198, 242, 245, 260, 272], 'cis-acting': [4], 'regulatory': [5, 248], 'sequences': [6, 83, 105], 'of': [7, 22, 26, 30, 40, 42, 69, 81, 93, 103, 107, 110, 117, 145, 158, 200, 206, 244, 251, 269], 'ninaE': [9, 44, 86, 91, 137, 261], 'gene.': [10], 'This': [11], 'gene': [12, 45, 58, 87, 262], 'encodes': [13], 'major': [15], 'Drosophila': [16, 63], 'melanogaster': [17], 'opsin,': [18], 'protein': [20], 'component': [21], 'primary': [24], 'chromophore': [25], 'photo-receptor': [27], 'cells': [28, 270], 'R1-R6': [29], 'adult': [32], 'eye.': [33], 'DNA': [34], 'fragments': [35], 'containing': [36, 96, 253], 'start': [38, 109], 'point': [39], 'transcription': [41, 111], 'were': [46, 121], 'fused': [47], 'to': [48, 77, 88, 123, 170, 176, 179, 234], 'either': [49], 'Escherichia': [51], 'coli': [52, 72], 'chloramphenicol': [53], 'acetyltransferase': [54], 'or': [55], 'lacZ': [56], '(beta-galactosidase)': [57], 'and': [59, 100, 154, 192, 194], 'introduced': [60], 'into': [61], 'germline': [64], 'by': [65], 'P-element-mediated': [66], 'transformation.': [67], 'Expression': [68], 'E.': [71], 'genes': [73, 255], 'was': [74, 221], 'then': [75], 'used': [76], 'assay': [78], 'ability': [80], 'various': [82], 'from': [84, 202, 230], 'confer': [89], 'pattern': [92], 'expression.': [94, 127], 'Fragments': [95], 'between': [97, 151, 189], '2.8': [98], 'kb': [99], '215': [101], 'bp': [102, 116], 'upstream': [106], 'plus': [112], 'first': [114, 246], '67': [115], 'untranslated': [119], 'leader': [120], 'able': [122, 178], 'direct': [124], 'nearly': [125], 'wild-type': [126], 'identified': [130], 'three': [131], 'separable': [132], 'control': [133, 184, 209, 226], 'regions': [134, 210], 'in': [135, 212, 216, 241, 266, 271], 'promoter.': [138, 204], 'The': [139, 156, 224], 'first,': [140], 'which': [141, 186, 195], 'has': [142], 'properties': [144], 'an': [146], 'enhancer': [147], 'element,': [148], 'is': [149, 187, 263], 'located': [150, 188, 228], 'nucleotides': [152, 190], '-501': [153], '-219.': [155], 'removal': [157], 'this': [159, 167, 203], 'sequence': [160, 168], 'had': [161], 'little': [162], 'effect': [163], 'on': [164], 'promoter': [165, 239], 'function;': [166], 'appears': [169, 175, 233], 'be': [171, 177, 235], 'redundant.': [172], 'However,': [173], 'it': [174], 'substitute': [180], 'for': [181, 238], 'second': [183], 'region': [185], '-215': [191], '-162,': [193], 'also': [196, 264], 'affects': [197], 'level': [199], 'output': [201], 'Removal': [205], 'these': [207], 'two': [208, 247], 'resulted': [211], 'a': [213, 267], '30-fold': [214], 'decrease': [215], 'expression;': [217], 'however': [218], 'tissue': [219], 'specificity': [220], 'not': [222], 'affected.': [223], 'third': [225], 'region,': [227], 'downstream': [229], 'nucleotide': [231], '-120,': [232], 'absolutely': [236], 'necessary': [237], 'function': [240], 'absence': [243], 'sequences.': [249], 'Examination': [250], 'larvae': [252], 'fusion': [254], 'expressing': [256], 'beta-galactosidase': [257], 'suggests': [258], 'that': [259], 'expressed': [265], 'subset': [268], 'larval': [273], 'photoreceptor': [274], 'organ.': [275]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2109825947', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-25T06:14:51.364455', 'created_date': '2016-06-24'}