Title: A Macrophage‐Targeted Theranostic Nanoparticle for Biomedical Applications
Abstract: SmallVolume 2, Issue 8-9 p. 983-987 Communication A Macrophage-Targeted Theranostic Nanoparticle for Biomedical Applications† Jason R. McCarthy Dr., Jason R. McCarthy Dr. [email protected] Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this authorFarouc A. Jaffer Dr., Farouc A. Jaffer Dr. Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this authorRalph Weissleder Prof., Ralph Weissleder Prof. [email protected] Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this author Jason R. McCarthy Dr., Jason R. McCarthy Dr. [email protected] Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this authorFarouc A. Jaffer Dr., Farouc A. Jaffer Dr. Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this authorRalph Weissleder Prof., Ralph Weissleder Prof. [email protected] Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA, Fax: (+1) 617-726-5708Search for more papers by this author First published: 28 July 2006 https://doi.org/10.1002/smll.200600139Citations: 122 † This work was supported by a National Institutes of Health (NIH) T32 Fellowship and by NIH grants CA79443, R01 HL080731, and P50 CA86355 (all to R.W.). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Diagnosis and therapy in one: Many prevalent diseases, such as atherosclerosis, could be efficiently treated by localized, macrophage-targeted therapies. A biocompatible nanoparticle with high macrophage avidity is presented; the nanoparticle has magnetic and fluorescence, as well as therapeutic, imaging functionalities. Multimodal detection and exquisite phototoxicity to macrophages under appropriate illumination is shown (see image). 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Publication Year: 2006
Publication Date: 2006-07-28
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 150
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