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'Centorrino,': [49], 'Richard': [51, 159], 'Wang,': [52], 'Starr': [55, 169], 'Grundy,': [57], 'B.Sc.Pharm.,': [58, 178], 'Michael': [59, 179], 'Greaney,': [61], 'M.S.,': [62, 188], 'Thomas': [63, 189], 'Jacobs,': [65], 'M.A.S.,': [66, 198], 'Stacy': [67, 199], 'R.': [68, 200], 'David,': [69], 'Verna': [71, 209], 'Toma,': [72], 'B.S.,': [73, 217], 'and': [74, 218, 255, 259, 439, 457, 467, 519, 545, 555, 632, 637, 640, 714, 767, 857, 879, 913, 923, 937, 954, 962, 976, 990, 998, 1105, 1118, 1141, 1165, 1170, 1252, 1274, 1316, 1350, 1539, 1577, 1682, 1692, 1702, 1733, 1782, 1793, 1824, 1943, 1953, 2010, 2132, 2158, 2174, 2180, 2255, 2265, 2319, 2326, 2406, 2416, 2491, 2495, 2498, 2504, 2514, 2536, 2542, 2545, 2555, 2561, 2567, 2695, 2774, 2812, 2825, 2846, 2870, 2995, 3039, 3081, 3084, 3091, 3191, 3200, 3232, 3247, 3279, 3303, 3329, 3383, 3401, 3429, 3435, 3498, 3522, 3551, 3583, 3606, 3646, 3659, 3699, 3765, 3798, 3861, 3951, 3972, 4039, 4047, 4049, 4058, 4080, 4191, 4304, 4328, 4366], 'The': [75, 219, 244, 268, 348, 396, 484, 1110, 1246, 1513, 1543, 1582, 1837, 1957, 2126, 2205, 2283, 2686, 2727, 3779], 'Olanzapine': [76, 220, 2368], 'HGEH': [77, 221], 'Study': [78, 222, 1188], 'GroupMauricio': [79], 'TohenSearch': [80], 'for': [81, 92, 102, 112, 123, 133, 142, 152, 161, 172, 182, 192, 202, 211, 224, 498, 650, 667, 675, 752, 816, 824, 1013, 1034, 1243, 1373, 1509, 1518, 1790, 1821, 1883, 2361, 2679, 3229, 3317, 3332, 3485, 3706, 3759, 3835, 3887, 3919, 3946, 3949, 3953, 3970, 3974, 4115, 4201, 4214], 'more': [82, 93, 103, 113, 124, 134, 143, 153, 162, 173, 183, 193, 203, 212, 225, 385, 424, 444, 1356, 2629, 2779, 3157], 'papers': [83, 94, 104, 114, 125, 135, 144, 154, 163, 174, 184, 194, 204, 213, 226], 'by': [84, 95, 105, 115, 126, 136, 145, 155, 164, 175, 185, 195, 205, 214, 227, 333, 623, 736, 1145, 1230, 1419, 1442, 2744, 3059, 3132, 3141, 3490, 3510, 3936, 3992, 4037, 4050, 4078, 4101, 4224, 4254], 'this': [85, 96, 106, 116, 127, 137, 146, 156, 165, 176, 186, 196, 206, 215, 228, 248, 487, 3559, 3679, 3732, 3841, 3993], 'author,': [86, 97, 107, 117, 128, 138, 147, 157, 166, 177, 187, 197, 207, 216], 'SangerSearch': [91], 'McElroySearch': [101], 'TollefsonSearch': [111], 'ChengappaSearch': [122], 'DanielSearch': [132], 'PettySearch': [141], 'CentorrinoSearch': [151], 'WangSearch': [160], 'GrundySearch': [171], 'GreaneySearch': [181], 'JacobsSearch': [191], 'DavidSearch': [201], 'TomaSearch': [210], 'GroupSearch': [223], 'authorPublished': [229], 'Online:1': [230], 'May': [231], '1999https://doi.org/10.1176/ajp.156.5.702AboutSectionsView': [232], 'articleAbstractPDF/EPUB': [233], 'ToolsAdd': [234], 'favoritesDownload': [236], 'CitationsTrack': [237], 'Citations': [238], 'ShareShare': [239], 'onFacebookTwitterLinked': [240], 'InEmail': [241], 'View': [242], 'articleAbstractOBJECTIVE:': [243], 'primary': [245, 349, 1212, 1841, 2097, 4290], 'intent': [246], 'study': [249, 277, 488, 945, 971, 985, 1007, 1111, 1228, 1889, 2823, 3045, 3277, 3287, 3426, 3572, 3601, 3687, 3733, 3787, 3859, 3935, 3963, 4016, 4100, 4123, 4144, 4154, 4209], 'was': [250, 355, 375, 977, 1062, 1081, 1088, 1112, 1122, 1130, 1143, 1182, 1210, 1331, 1464, 1521, 1621, 1763, 1768, 1775, 1815, 1881, 1960, 2054, 2083, 2135, 2189, 2241, 2369, 2387, 2443, 2470, 2713, 2829, 2901, 2966, 3108, 3311, 3518, 3614, 3704, 3749, 3788, 3877, 3990, 4029, 4068, 4145, 4171, 4180, 4272], 'compare': [252, 2086], 'efficacy': [254, 350, 497, 570, 947, 1213, 1636, 1691, 1781, 1823, 1829, 1842, 2088, 2098, 2278, 3107, 3280, 3484, 3538], 'safety': [256, 624, 1783, 1825], 'olanzapine': [258, 295, 397, 480, 494, 860, 891, 930, 1303, 1315, 1538, 1948, 2115, 2131, 2197, 2262, 2284, 2413, 2425, 2517, 2581, 2633, 2656, 2687, 2783, 3016, 3048, 3114, 3124, 3295, 3310, 3400, 3406, 3428, 3455, 3472, 3605, 3624, 3669, 3737, 3983, 4005, 4303, 4343], 'placebo': [260, 298, 310, 413, 433, 1389, 1391, 1925, 2124, 2133, 2200, 2305, 2526, 2584, 2636, 2667, 2788, 3120, 3316, 3402, 3607, 3986, 4024, 4034, 4074, 4120, 4174, 4206, 4287], 'treatment': [263, 472, 481, 535, 546, 574, 682, 950, 1301, 1544, 1631, 1819, 1977, 2194, 2339, 2359, 2833, 2882, 2941, 2992, 3053, 3102, 3138, 3185, 3351, 3376, 3415, 3531, 3708, 3735, 3821, 3842, 3989, 4008, 4063, 4213, 4223], 'acute': [265, 502, 576, 952, 1370, 1893, 1914, 2081, 2725, 2955, 3055, 3375, 3417, 3783, 3824, 3870, 3897, 4062], 'mania.': [266, 503, 2176], 'METHOD:': [267], 'design': [269], 'involved': [270], 'a': [271, 283, 358, 377, 380, 509, 514, 585, 796, 813, 829, 835, 847, 969, 1131, 1255, 1281, 1307, 1324, 1338, 1351, 1454, 1500, 1590, 1599, 1680, 1683, 1700, 1703, 1869, 2008, 2031, 2164, 2209, 2213, 2287, 2312, 2373, 2602, 2604, 2610, 2659, 2902, 3290, 3424, 3544, 3569, 3626, 3690, 3742, 3752, 3847, 3878, 3960, 4018, 4172, 4266, 4283], 'random-assignment,': [272], 'double-blind,': [273, 1133], 'placebo-controlled': [274, 1134], 'parallel': [275, 1135], 'group': [276, 398, 1136, 1890, 2116, 2426, 2518, 2527, 2585, 2657, 2668, 2784, 2789, 3115, 3121], '3': [279, 1084, 1091, 1103, 1347, 1374, 1489, 2448, 2564, 3809], 'weeks’': [280, 1047], 'duration.': [281, 1048], 'After': [282, 315, 1333, 1401], '2-': [284, 1282], '4-day': [286, 1284], 'screening': [287], 'period,': [288], 'qualified': [289, 1292], 'patients': [290, 426, 459, 589, 677, 698, 710, 854, 896, 935, 940, 975, 1293, 1311, 1336, 1527, 1586, 1661, 1698, 1719, 1808, 1908, 1911, 1923, 1983, 2024, 2029, 2040, 2171, 2178, 2207, 2233, 2252, 2285, 2306, 2403, 2630, 2729, 2795, 2806, 2886, 2913, 2919, 2999, 3099, 3150, 3199, 3265, 3432, 3441, 3619, 3653, 3683, 3712, 3730, 3867, 3890, 4088], 'were': [291, 449, 703, 1001, 1042, 1065, 1073, 1224, 1261, 1294, 1312, 1528, 1534, 1562, 1575, 1580, 1588, 1597, 1648, 1662, 1669, 1706, 1725, 1753, 1797, 1835, 1866, 1949, 1969, 2145, 2184, 2259, 2280, 2410, 2508, 2819, 2852, 2878, 2937, 3018, 3176, 3587, 3641, 3714, 3772, 3891, 3944, 3968, 4096, 4105, 4308, 4321, 4355], 'assigned': [292, 431, 1296, 1313, 1536, 1660, 1721], 'either': [294, 305, 1016, 1381, 2881, 2940], '(N=70)': [296], 'or': [297, 309, 328, 384, 604, 608, 905, 1018, 1022, 1039, 1086, 1098, 1304, 1348, 1355, 1388, 1414, 1556, 1989, 2153, 2161, 2612, 2766, 3156, 3458, 3592, 3634, 3725], '(N=69).': [299], 'Patients': [300, 1064, 1376, 1561, 4013], 'began': [301, 1229, 1377], 'double-blind': [302, 850, 970, 1378, 1723, 2769, 3044, 3896], 'therapy': [303, 1371, 1379, 1724, 2797, 2921], 'with': [304, 446, 460, 492, 513, 590, 635, 644, 711, 792, 803, 855, 897, 903, 929, 961, 1184, 1218, 1238, 1254, 1263, 1337, 1380, 1550, 1609, 1699, 1711, 1868, 2172, 2179, 2208, 2253, 2261, 2303, 2331, 2372, 2404, 2412, 2579, 2860, 2928, 2993, 3010, 3015, 3166, 3206, 3433, 3450, 3595, 3620, 3623, 3643, 3654, 3736, 3873, 3926, 3985, 4302], 'olanzapine,': [306, 1382, 2994, 3507], '10': [307, 1383, 2707], 'mg,': [308], 'given': [311, 1393], 'once': [312, 1394], 'per': [313, 1395, 1459, 1809], 'day.': [314], 'first': [317, 1403, 1480, 2474, 2764], 'day': [318, 1404, 4159, 4189], 'treatment,': [320, 1406, 1791], 'daily': [322, 1408, 1964, 2035, 2064], 'dose': [323, 1409, 1502, 1959, 1965, 2006, 2017, 2036, 2065, 4140], 'could': [324, 1364, 1410, 1437, 1493, 1506, 4246], 'be': [325, 688, 812, 893, 1365, 1411, 1494, 1507, 1709, 3274, 3289, 3466, 3846, 4247], 'adjusted': [326, 1412], 'upward': [327, 1413], 'downward,': [329, 1415], 'as': [330, 357, 379, 560, 1416, 1736, 1738, 1770, 1844, 1874, 1905, 1909, 1962, 2167, 2169, 2606, 2742, 3057, 3139, 3305, 3488, 3508, 3566], 'clinically': [331, 1368, 1417, 2872, 2931, 3716], 'indicated,': [332, 1418], 'one': [334, 344, 563, 1298, 1457, 1920, 1936, 2005, 2016, 2813], 'capsule': [335], '(olanzapine,': [336], '5': [337, 2836], 'mg/day)': [338], 'within': [339, 1083, 1090, 1100, 1422], 'allowed': [341, 1424, 3892, 4141, 4181], 'range': [342, 1426], 'four': [346, 1938], 'capsules.': [347], 'measure': [351], 'protocol': [354, 1838, 2600], 'defined': [356, 376, 1961, 2601], 'change': [359, 1675, 1715, 1847, 2069, 2100, 2217, 2247, 2345, 2393, 2864, 3030], 'from': [360, 386, 486, 1197, 1716, 1750, 1755, 1799, 1833, 1848, 2070, 2101, 2218, 2248, 2292, 2346, 2394, 2624, 2865, 2895, 3012, 3031, 3685], 'baseline': [361, 387, 1198, 1553, 1634, 1681, 1690, 1701, 1731, 1834, 1849, 2071, 2102, 2219, 2249, 2293, 2335, 2347, 2395, 2625, 2866, 2896, 3032], 'endpoint': [363, 1200, 1851, 2073, 2104, 2349, 3034], 'total': [365, 393, 409, 1051, 1202, 1362, 1524, 1766, 1861, 2106, 2225, 2317, 2354, 2381, 2400, 2433, 2468, 2549, 2616, 3063, 3083, 3163, 3381, 3516], 'score': [366, 410, 1052, 1203, 1242, 1345, 1363, 1767, 2382, 2469, 2617], 'on': [367, 868, 917, 968, 1026, 1055, 1204, 1635, 1650, 1657, 2108, 2147, 2275, 2323, 2435, 2593, 2618, 2669, 2887, 3065, 3076, 3088, 3307, 3768, 3979, 4195, 4314, 4363], 'Young': [369, 389, 405, 1057, 1151, 1206, 1220, 1358, 1857, 2110, 2221, 2437, 2464, 2620, 3067, 3159, 3238, 3252, 3320, 3512, 4294], 'Mania': [370, 390, 406, 1058, 1152, 1207, 1221, 1359, 1858, 2111, 2222, 2438, 2465, 2621, 2651, 3068, 3160, 3239, 3253, 3321, 3513, 4295], 'Rating': [371, 391, 407, 1059, 1153, 1160, 1208, 1222, 1266, 1360, 1859, 2112, 2223, 2439, 2466, 2622, 2652, 3069, 3161, 3240, 3254, 3322, 3514, 4296], 'Scale.': [372, 3094, 3501], 'Clinical': [373, 1032, 1172], 'response': [374, 421, 798, 3136, 3175, 3505, 4022, 4027, 4035, 4075, 4118, 4175, 4204], 'priori': [378, 2605], 'decrease': [381, 2291, 2614], '50%': [383, 1354, 2611, 3155], 'Scale': [392, 408, 1060, 1154, 1161, 1168, 1209, 1223, 1267, 1272, 1279, 1361, 1860, 2224, 2467, 2501, 2548, 2570, 2623, 2653, 3162, 3241, 3255, 3323, 3515], 'score.': [394], 'RESULTS:': [395], 'experienced': [399, 2117, 4017], 'significantly': [400, 423, 443, 1548, 2032, 2118, 2214, 2288, 2313, 2520, 2589, 2731, 2778, 2854, 2967, 3109, 3313, 3330, 4069, 4299], 'greater': [401, 2033, 2119, 2215, 2289, 2314, 2429, 2521, 2590, 2613, 2661, 2689, 2732], 'mean': [402, 1846, 1941, 2034, 2063, 2120, 2127, 2216, 2246, 2290, 2344, 2392, 2430, 2463, 2591, 2662, 2690, 2863, 2903, 3029, 3743], 'improvement': [403, 2121, 2362, 2431, 2461, 2522, 2592, 2663, 2691, 2733, 3153, 3213, 3444, 4245], 'than': [411, 429, 749, 2037, 2122, 2229, 2634, 2738, 2785, 3117, 4071], 'group.': [414, 482, 2125, 2883, 2942], 'On': [415, 723, 3955], 'basis': [417, 919, 1028, 2149], 'clinical': [420, 3001, 3181, 3660, 3815, 3855, 4259], 'criteria,': [422], 'olanzapine-treated': [425, 456, 1907, 1939, 2039, 2206, 2455, 2728, 2794, 2885, 3149, 3440, 3682, 3930, 4243], '(48.6%)': [427], 'responded': [428, 2631], 'those': [430, 715, 902, 1608, 3219], '(24.2%).': [434, 4025], 'Somnolence,': [435], 'dizziness,': [436, 2773], 'dry': [437, 2771], 'mouth,': [438, 2772], 'weight': [440, 2775, 2894, 2904, 3740, 3744, 3767], 'gain': [441, 2776, 3745], 'occurred': [442, 477, 2777, 3918], 'often': [445, 1967], 'olanzapine.': [447, 3907], 'There': [448, 2053, 2240, 2386, 3876], 'no': [450, 1639, 1970, 2055, 2190, 2242, 2357, 2389, 2714, 2793, 3019, 3392, 3602, 3681, 3715, 3729, 4319, 4356], 'statistically': [451, 1643, 1971, 2444, 2715], 'significant': [452, 1644, 1972, 2056, 2243, 2358, 2374, 2445, 2716, 2873, 2932, 3020, 3393, 3443, 3717, 4306], 'differences': [453, 1973, 3021, 3275, 3394, 4307, 4320, 4358], 'between': [454, 517, 987, 993, 1250, 1974, 2058, 2129, 2170, 2250, 2402, 2718, 2856, 2969, 3022, 3398, 3604], 'placebo-treated': [458, 1910, 2028, 2232, 2740, 2805, 2912, 3170, 3209, 3884, 3923], 'respect': [461, 1551, 2861], 'measures': [463, 869, 3281], 'parkinsonism,': [465], 'akathisia,': [466], 'dyskinesias.': [468], 'No': [469, 2918, 3977], 'discontinuations': [470], 'due': [473], 'adverse': [475, 1435, 1746, 2760, 2801, 2925, 3612, 3692], 'events': [476, 1436, 2761], 'CONCLUSIONS:': [483], 'results': [485, 4301, 4313], 'suggest': [489, 889], 'that': [490, 550, 584, 626, 769, 838, 842, 890, 972, 1079, 1654, 2763, 2838, 3047, 3195, 3261, 3271, 3325, 3338, 3405, 3480, 3576, 4086, 4148, 4264, 4338, 4353], 'compared': [491, 1934, 2185, 2302, 3165, 3205, 3925, 3984, 4044, 4056], 'placebo,': [493, 1305, 4048, 4059, 4305], 'has': [495, 529, 670, 759, 785, 3335, 3456, 3473, 4130], 'superior': [496, 862, 3314, 3331, 3483], 'symptoms': [500, 907, 1260, 1520, 2365, 2818, 3002, 3328, 3343, 3361, 3397, 3438, 3447, 3487, 3493, 3550, 3632, 3697, 3801, 4372], 'Bipolar': [504, 1176, 1340, 2296, 2483, 3079, 3385, 4331], 'disorder': [505, 512, 656, 899, 960, 3354, 3421, 3463, 3828], '(manic-depressive': [506], 'illness)': [507], 'is': [508, 580, 734, 746, 801, 1898, 3049, 3129, 3477, 3539, 3757, 4084, 4124, 4207, 4262, 4350], 'chronic': [510], 'episodic': [511], 'lifetime': [515], 'prevalence': [516], '0.8%': [518], '1.6%': [520], '(1–3).': [521], 'Over': [522], 'past': [524, 1102], 'several': [525, 3773], 'decades,': [526], 'substantial': [527, 586], 'progress': [528, 3999], 'been': [530, 787, 3336, 3555, 4131], 'made': [531], 'pharmacologic': [534, 822, 836], 'manic': [538, 652, 904, 953, 1017, 1591, 3223, 3244, 3258, 3301, 3581, 3803, 3871], 'phase': [539, 653, 1894, 1915, 2082, 3784, 3898], 'bipolar': [541, 655, 676, 732, 777, 827, 898, 939, 958, 1014, 3353, 3367, 3420, 3462, 3655, 3677, 3827, 4010], 'disorder.': [542, 3656, 4011], 'Numerous': [543], 'authorities': [544], 'guidelines': [547], 'presently': [548], 'recognize': [549], 'three': [551], 'individual': [552, 1757, 2654, 3300], 'agents—lithium,': [553], 'valproate,': [554], 'carbamazepine': [556], '(typically': [557], 'referred': [558], 'mood': [561, 877, 927, 2681, 3327], 'stabilizers)—and': [562], 'class': [564], 'agents—the': [566], 'conventional': [567, 865, 3339, 3363, 3526, 3561, 3589], 'antipsychotics—have': [568], 'proven': [569], 'short-term': [573, 3414], 'mania': [577, 591, 1344, 2257, 2300, 2408, 2494, 2531, 3074, 3187, 3418, 3533, 3825], '(4–10).However,': [578], 'it': [579, 800, 3476, 3481, 3756, 4067], 'also': [581, 786, 2281, 2310, 2388, 2509, 3831], 'well': [582, 1737, 2168], 'recognized': [583], 'proportion': [587], 'fail': [592], 'respond': [594, 719, 4092, 4109], 'adequately': [595], 'these': [597, 619, 692, 921, 3639], 'agents,': [598, 4342], 'whether': [599, 3454], 'they': [600, 1677, 3345], 'are': [601, 609, 621, 657, 770, 3346, 3563, 3997, 4373], 'used': [602, 1508, 1776, 1816, 1882, 1985, 2084, 3221, 3347, 3832], 'alone': [603, 3591], 'various': [606], 'combinations,': [607], 'unable': [610], 'tolerate': [612], 'them': [613], '(9,': [614], '10).': [615, 4160], 'Moreover,': [616, 3502], 'all': [617, 1288, 1658, 1884, 1998, 2670, 2982, 3711, 4315], 'agents': [620, 755, 805, 823, 3528], 'characterized': [622], 'concerns': [625, 3542, 3797, 3864], 'necessitate': [627], 'regular': [628], 'monitoring': [629], '(e.g.,': [630, 764], 'renal': [631], 'thyroid': [633], 'toxicity': [634], 'lithium': [636, 4094], 'tardive': [638, 3552, 3635, 3674], 'dyskinesia': [639, 3553, 3636, 3675], 'neuroleptic': [641], 'malignant': [642], 'syndrome': [643, 3224], 'typical': [645, 914], 'antipsychotics).': [646], 'Novel': [647], 'medical': [648, 814], 'treatments': [649, 2092], 'therefore': [658], 'needed.The': [659], 'success': [660], 'novel': [663, 821, 832], 'antipsychotic': [664, 754, 782, 866, 3364, 3474, 3527, 4341], 'agent': [665], 'clozapine': [666, 706, 730, 758, 844], 'treatment-resistant': [668], 'schizophrenia': [669, 856, 3434, 3621], 'resulted': [671], 'its': [673, 774], 'use': [674, 728, 775, 825, 1515, 2828, 3365, 3700, 3981, 4126], 'unresponsive': [678], 'usual': [681], 'strategies': [683], '(11–15).': [684], 'However,': [685, 2792, 2884, 2981, 3218, 3453, 3598, 3638, 3793, 4138], 'caution': [686], 'must': [687], 'applied': [689], 'interpreting': [691], 'data,': [693], 'since': [694, 4370], 'numbers': [696], 'evaluated': [699], 'controlled': [701, 817, 851, 3469], 'trials': [702, 852, 3182], 'small.': [704], 'Nonetheless,': [705], 'appears': [707, 3844], 'benefit': [709], 'rapid-cycling': [712, 1619, 2165, 2210], 'illness': [713, 733, 1077, 1140, 1559, 1734, 2490], 'who': [716, 1801, 1984, 2258, 2409, 3100, 4043, 4055, 4089, 4095], 'do': [717], 'not': [718, 1522, 1547, 1803, 2370, 2587, 2853, 3408, 3478, 3650, 3812, 4091, 4309, 4345, 4351, 4374], 'standard': [721], 'treatment.': [722, 1810, 2477, 3372], 'other': [725, 760, 1991, 3297, 3596, 3957, 4340], 'hand,': [726, 3958], 'limited': [735, 1465, 3789], 'relatively': [738, 2333], 'high': [739, 3879, 3914, 4019, 4117, 4203], 'incidence': [740, 1743], 'agranulocytosis': [742], '(annual': [743], 'rate=0.8%),': [744], 'which': [745, 3574, 3917, 4129, 4280], 'tenfold': [747], 'higher': [748, 3546, 4070], 'rate': [751, 3038, 3881, 4020, 4028, 4076], 'traditional': [753], '(16).': [756], 'Furthermore,': [757, 3616], 'troublesome': [761], 'side': [762], 'effects': [763, 1820, 3128, 3411, 3460, 3613, 3856, 4136], 'excessive': [765], 'salivation': [766], 'sedation)': [768], 'likely': [771, 4107], 'limit': [773], 'patients.': [778, 1627, 3171, 3452, 3885, 3931], 'Another': [779, 4198], 'recently': [780, 830], 'released': [781], 'agent,': [783], 'risperidone,': [784], 'studied': [788], 'open-label': [790, 887, 3906], 'designs,': [791], 'some': [793], 'studies': [794, 818, 888, 3014, 3617, 3640, 3658, 3819, 3996], 'suggesting': [795, 3404, 4337], 'favorable': [797], 'when': [799, 3344], 'combined': [802], 'mood-stabilizing': [804, 3298], '(17,': [806], '18).': [807], 'Accordingly,': [808], 'there': [809, 2188, 2712, 2900, 3272, 3713, 4170, 4354], 'continues': [810], 'need': [815], 'identify': [820], 'disorder.Olanzapine,': [828], 'introduced': [831], 'antipsychotic,': [833], 'demonstrates': [834], 'profile': [837], 'most': [839, 1966, 3285], 'closely': [840], 'resembles': [841], '(19).': [845], 'In': [846, 2095, 2577, 2943, 3373, 3423, 4161], 'series': [848], 'schizoaffective': [858, 938], 'disorder,': [859, 1015, 3368], 'appeared': [861, 2765], 'haloperidol': [867, 3430], 'overall': [871, 2487], 'psychotic': [872, 964, 1024, 1605, 1610, 1615, 2156, 2182, 3486, 3523], 'symptoms,': [873, 875, 878, 1611, 3259, 3304], 'negative': [874, 2505, 4360, 4371], 'comorbid': [876, 3436], 'quality': [880], 'life': [882, 1181], '(20–25).': [883], 'Recent': [884], 'reports': [885, 922], 'may': [892, 3125, 3273, 3649, 3909, 4281], 'efficacious': [894], '(26–28),': [900], 'including': [901], 'mixed': [906, 955, 1019, 1040, 1600, 2175, 2256, 2407], 'inadequately': [908], 'responsive': [909], 'lithium,': [911, 3950, 4046], 'anticonvulsants,': [912], 'anti\xadpsychotics.': [915], 'Thus,': [916, 4238], 'findings': [925, 3648], 'stabilization': [928], 'among': [931, 2821, 2910, 3882], 'both': [932, 1679, 2338, 2832, 3707], 'depressed': [933], 'schizophrenic': [934, 3644], '(20)': [936], '(29),': [941], 'we': [942], 'decided': [943], 'olanzapine’s': [946], 'episodes': [956, 1041], 'I': [959], 'without': [963, 1023, 2181], 'features.': [965, 1606, 1616], 'We': [966], 'report': [967], 'included': [973, 1663, 1670, 1726, 1787, 4097], '139': [974, 1526], 'conducted': [978, 1225, 3642], 'United': [981], 'States': [982], 'at': [983, 1044, 1439, 1633, 1805, 2003, 2014, 2446, 2562, 2596, 2950, 2963, 3006, 3215, 3267, 4182, 4215], '16': [984], 'sites': [986], 'October': [988], '1996': [989], 'August': [991], '1997.METHODPatients': [992], 'ages': [995], '18': [997], '65': [999], 'years': [1000], 'enrolled': [1002, 1529], 'study.': [1005, 1137, 1918, 1996, 3777, 3994], 'All': [1006, 1718], 'subjects': [1008], 'met': [1009], 'DSM-IV': [1011], 'criteria': [1012, 1072], 'episode': [1020, 3872], '(with': [1021], 'features),': [1025], 'Structured': [1031], 'Interview': [1033], 'DSM-III-R': [1035], '(SCID)': [1036], '(30).': [1037], 'Manic': [1038], 'least': [1045, 1806, 2004, 2015, 3216, 3268, 4216], '2': [1046, 1491, 1504, 2513], 'A': [1049, 1617, 4112], 'minimum': [1050, 1325, 1455], '20': [1054], '(31)': [1061], 'required.': [1063, 1332], 'excluded': [1066], 'if': [1067, 1367, 1472, 1676, 1759], 'any': [1068, 1440, 1443, 1642, 1760, 1990, 2594, 2597, 2607, 2951, 2964, 3007], 'following': [1071, 1147], 'met:': [1074], 'serious,': [1075], 'unstable': [1076], 'such': [1078], 'hospitalization': [1080, 1330], 'anticipated': [1082, 1089], 'months': [1085], 'death': [1087], 'years;': [1092], 'DSM-IV-defined': [1093, 1618], 'substance': [1094], 'dependence': [1095], '(except': [1096], 'nicotine': [1097], 'caffeine)': [1099], 'months;': [1104], 'serious': [1106, 3691], 'risk': [1107, 3547, 3628], 'suicide.': [1109], 'fully': [1113], 'explained': [1114], 'each': [1116, 1235, 1244], 'patient,': [1117], 'written': [1119], 'informed': [1120], 'consent': [1121], 'obtained': [1123], 'before': [1124, 1226], 'their': [1125, 1565, 2735, 3537], 'participation': [1126, 4255], 'study.This': [1129], 'randomized,': [1132, 3042], 'Severity': [1138], 'psychopathology': [1142], 'measured': [1144, 2743, 3489, 3509], 'rating': [1148, 1751, 4291], 'scales:': [1149], '(31),': [1155], '21-item': [1157], 'Hamilton': [1158, 2351, 2378, 2397, 3378, 4324], 'Depression': [1159], '(32),': [1162], 'Positive': [1164, 2325, 2497, 2544, 2566, 3090, 3497, 4365], 'Negative': [1166, 2327, 2499, 2546, 2568, 3092, 3499, 4367], 'Syndrome': [1167, 2328, 2500, 2547, 2569, 3093, 3500, 4368], '(33),': [1169], 'Global': [1173], 'Impression': [1174], '(CGI),': [1175], 'Version': [1177], '(34).': [1178], 'Quality': [1179], 'assessed': [1183, 1262], 'Medical': [1186], 'Outcomes': [1187], '36-item': [1189], 'Short-Form': [1190], 'Health': [1191], 'Survey': [1192], '(SF-36)': [1193], '(35,': [1194], '36)': [1195], 'Change': [1196], 'measure.': [1214], 'Interrater': [1215], 'reliability': [1216], 'assessments': [1217], 'measuring': [1231, 3853], 'correlation': [1233, 1247], 'rater’s': [1236], 'scoring': [1237], 'groupwise': [1240], 'median': [1241, 1256, 1944], 'item.': [1245], 'coefficients': [1248], 'ranged': [1249], '0.76': [1251], '0.99,': [1253], '0.94.': [1258], 'Extrapyramidal': [1259], 'Simpson-Angus': [1265], '(37),': [1268], 'Barnes': [1270], 'Akathisia': [1271], '(38),': [1273], 'Abnormal': [1276], 'Involuntary': [1277, 2849], 'Movement': [1278, 2850], '(39).After': [1280], 'washout': [1285], 'period': [1286, 3843], 'medications': [1289, 1463, 1993], 'except': [1290, 2672], 'benzodiazepines,': [1291, 1988, 2026], 'randomly': [1295, 1535, 1659, 1720], 'two': [1300, 1807, 1922, 1976, 2060, 2091, 2720, 2804, 2858, 2971, 3179, 3319], 'groups,': [1302, 2340, 3403], '1:1': [1308], 'ratio.': [1309], 'Seventy': [1310], '69': [1317, 1540], 'placebo.': [1319, 1542, 2385, 3874, 3954, 3975, 4111], 'To': [1320], 'ensure': [1321], 'patient': [1322, 1554, 1732, 2608], 'safety,': [1323], '1': [1327, 1334, 3900, 4193, 4217], 'week': [1328, 2447, 2475, 2563, 3901], 'week,': [1335], 'CGI,': [1339, 2295, 2482, 3078, 3384, 4330], 'Version,': [1341, 2297, 2484, 3386, 4332], 'severity': [1342, 1557, 2298, 2488, 2492, 2529, 3072, 3387, 4333], 'lower': [1349, 4183], 'reduction': [1352, 2315], 'discharged,': [1366], 'appropriate.Double-blind': [1369], 'lasted': [1372], 'weeks.': [1375], 'mg': [1384], '(two': [1385, 1390], '5-mg': [1386, 1420], 'tablets),': [1387, 1392], 'day,': [1396], 'preferably': [1397], 'evening.': [1400], 'increments/decrements': [1421], 'dosage': [1425, 1432], '5–20': [1428], 'mg/day.': [1429], 'Decreases': [1430], 'because': [1433, 1929, 2798, 2809, 2814, 2922, 3103, 3688, 3794], 'occur': [1438], 'time': [1441, 2952, 2965, 3849], 'number': [1444, 1981, 4268], 'one-tablet': [1446], '(5-mg)': [1447], 'decrements': [1448], '(at': [1449], 'investigator’s': [1451], 'discretion),': [1452], 'tablet': [1458], 'day.Use': [1460], 'concomitant': [1462, 1992], 'lorazepam,': [1467, 4128], 'up': [1468, 1498, 3577, 4157, 4187], '4': [1470, 4190], 'mg/day,': [1471, 1505, 1955, 2043, 2047], 'necessary,': [1473], 'alleviate': [1475], 'severe': [1476, 3800], 'agitation': [1477], 'during': [1478, 1486, 1891, 1994, 2768, 2953, 2990], '7': [1481], 'days': [1482, 3834, 4196], 'therapy;': [1484], 'then,': [1485], 'next': [1488], 'days,': [1490], 'mg/day': [1492, 1951, 4156, 4186, 4194], 'used.': [1495], 'Also,': [1496, 3095], 'benztropine,': [1497], 'maximum': [1501], 'treatment-emergent': [1510, 1745, 2947], 'extrapyramidal': [1511, 1519, 1693, 3549, 3611, 3631, 3696, 3726], 'symptoms.': [1512, 3245, 3727, 4348], 'prophylactic': [1514], 'benztropine': [1517], 'allowed.A': [1523], 'study;': [1532], '70': [1533], 'groups': [1545, 1632, 1978, 2061, 2134, 2721, 2859, 2972, 3024], 'did': [1546, 1802, 2230, 2586, 2698, 4090], 'differ': [1549], 'characteristics': [1555, 1735], 'ratings.': [1560], 'generally': [1563, 4375], 'late': [1566], '30s': [1567], '(mean': [1568], 'age=39.5': [1569], 'years,': [1570], 'SD=11.0),': [1571], 'majority': [1573, 1583], '(72.7%)': [1574], 'Caucasian,': [1576], 'half': [1578], '(51.8%)': [1579], 'male.': [1581], '(82.7%)': [1587], 'experiencing': [1589, 1598], 'episode,': [1592], 'while': [1593], 'rest': [1595], '(17.3%)': [1596], 'episode.': [1601], 'Overall,': [1602], '53.2%': [1603], 'displayed': [1604, 1613, 3000], 'Of': [1607, 1997, 2022], '85.1%': [1612], 'mood-congruent': [1614], 'course': [1620, 2166, 2211, 4277], 'present': [1622], '32.4%': [1624], 'Comparisons': [1628], 'variables': [1637], 'demonstrated': [1638, 2519, 2658, 3482], 'evidence': [1640], 'differences.All': [1645], 'statistical': [1646, 2684, 2700], 'analyses': [1647, 2144, 2479], 'done': [1649], 'an': [1651, 2019, 2800, 2924, 3152, 3212, 3769, 3869, 4257], 'intent-to-treat': [1652], 'basis;': [1653], 'is,': [1655], 'data': [1656, 1668], 'analysis.': [1666], 'Patients’': [1667], 'analysis': [1673, 1688, 1713, 1729, 1740, 1843, 2342, 2945, 3027], 'had': [1678, 1926, 2286, 2311, 2730, 3151, 3211], 'postbaseline': [1684, 1704], 'observation.': [1685], 'For': [1686, 1827, 2453, 3710], 'symptom': [1694, 2321, 2506, 3086, 4361], 'scores,': [1695], 'only': [1696, 3465], 'observation': [1705, 1853, 2075], 'included,': [1707], 'consistent': [1710, 3009], 'baseline.': [1717], 'events.': [1747], 'Total': [1748], 'scores': [1749, 2107, 2226, 2274, 2301, 2318, 2322, 2355, 2401, 2434, 2507, 2550, 2572, 3064, 3087, 3382, 3390, 4327, 4362], 'scales': [1752, 2279], 'derived': [1754], 'items;': [1758], 'single': [1761], 'item': [1762], 'missing,': [1764], 'treated': [1769, 2260, 2411, 3622], 'missing.Analysis': [1771], 'variance': [1773], '(ANOVA)': [1774], 'evaluate': [1778], 'continuous': [1780], 'variables;': [1784], 'models': [1786], 'terms': [1789, 3609], 'investigator,': [1792], 'treatment-by-investigator': [1794], 'interaction.': [1795], 'Data': [1796], 'pooled': [1798], 'investigators': [1800, 3220], 'have': [1804, 3126, 3409, 3554, 3910, 4134], 'Fisher’s': [1811, 2648, 2978], 'exact': [1812, 2649, 2979], 'test,': [1813], 'two-tailed,': [1814, 1867], 'analyze': [1818], 'categorical': [1822], 'variables.': [1826], 'selected': [1828], 'variables,': [1830], 'weekly': [1831], 'changes': [1832, 2874, 2933, 3718], 'analyzed.': [1836], 'established': [1839], '(last': [1852, 2074], 'carried': [1854, 2076], 'forward)': [1855, 2077], 'score.All': [1862], 'cited': [1863], 'p': [1864], 'values': [1865, 2336, 2936, 2949, 2962, 2986], 'significance': [1870], 'level': [1871, 4227], '0.05': [1873], 'specified': [1875], 'protocol.': [1878], 'SAS': [1879], '(40)': [1880], 'analyses.RESULTSThe': [1885], 'disposition': [1886], 'trial': [1897, 3293, 3807], 'shown': [1899, 3306], '1.': [1902], 'Almost': [1903], 'twice': [1904], 'many': [1906], 'completed': [1912], 'Nearly': [1919], 'receiving': [1924, 2025], 'discontinue': [1928, 3894], 'lack': [1931, 3105], 'efficacy,': [1933], 'patients.The': [1940], 'modal': [1942, 1945, 1958], 'doses': [1946, 4184], '14.9': [1950], '(SD=5.0)': [1952], '15': [1954], 'respectively.': [1956], 'taken.There': [1968], 'anticholinergic': [1986, 2020, 2827, 3702], 'medication,': [1987], 'patients,': [1999, 2456, 2741, 3204, 3210, 3645, 3804, 3924, 4270], '86.3%': [2000], '(N=120)': [2001], 'took': [2002, 2013], 'benzodiazepine,': [2009], '9.4%': [2011], '(N=13)': [2012], 'medication.': [2021], 'received': [2030], '(placebo:': [2041], 'mean=1.7': [2042], 'SD=1.3;': [2044], 'olanzapine:': [2045], 'mean=1.1': [2046], 'SD=1.2;': [2048], 'F=10.42,': [2049], 'df=1,': [2050, 2202, 2237, 2270, 2421, 2450, 2533, 2538, 2552, 2557, 2574, 2757, 2915], '102,': [2051], 'p=0.002).': [2052], 'difference': [2057, 2128, 2191, 2244, 2390, 2442, 2678, 2717, 3603], 'anticholinergics.EfficacyEndpoint': [2067], 'analysisMean': [2068], '3-week': [2080, 2724, 3753], '(table': [2093, 2307, 2366, 2674, 2790], '2).': [2094, 2308, 2367], 'analysis,': [2099, 3144], 'Scale,': [2113, 4297, 4369], '–5.38': [2136], 'points': [2137], '(95%': [2138], 'confidence': [2139], 'interval=–10.31': [2140], '–0.93).': [2142], 'Subgroup': [2143], 'performed': [2146], 'presence': [2152, 2160], 'absence': [2154, 2162], 'features': [2157, 2183], 'pure': [2173, 2254, 2405], 'When': [2177], '(Figure': [2186], '1),': [2187], 'advantage': [2195], 'relative': [2198, 2383, 2523, 2664], '(F=0.02,': [2201], '106,': [2203, 2553, 2558, 2575], 'p=0.88).': [2204], 'showed': [2212, 2356, 2428, 3391, 3442, 3575, 4298], '(mean=–13.89,': [2227], 'SD=7.97)': [2228], '(mean=–4.12,': [2234], 'SD=11.45)': [2235], '(F=7.25,': [2236], '35,': [2238], 'p=0.01).': [2239], '(mean=–10.84,': [2263], 'SD=13.72,': [2264], 'mean=–7.42,': [2266], 'SD=12.06,': [2267], 'respectively;': [2268, 2419], 'F=0.01,': [2269], '55,': [2271], 'p=0.91).Analyses': [2272], 'secondary': [2277, 3738], 'performed.': [2282, 2510], 'They': [2309], 'positive': [2320, 2571, 3085, 3492], 'Scale.As': [2329], 'expected': [2330], 'low': [2334], 'depression': [2352, 2379, 2398, 3379, 3389, 4325, 4335], 'scale': [2353, 2380, 2399, 2595, 3380, 4326], 'advantages': [2360], 'depressive': [2364, 3342, 3360, 3396, 3437, 3446, 4347], 'associated': [2371, 2927], 'baseline-to-endpoint': [2375], 'worsening': [2376], '(mean=–2.95,': [2414], 'SD=6.10,': [2415], 'mean=–2.67,': [2417], 'SD=9.55,': [2418], 'F=0.14,': [2420], '54,': [2422], 'p=0.71).Weekly': [2423], 'analysisThe': [2424, 2599], 'consistently': [2427], 'Scale;': [2440, 3070], '(F=5.64,': [2449], '108,': [2451, 2534, 2539], 'p=0.02).': [2452], '81%': [2457], 'last-observation-carried-forward': [2460], 'achieved': [2471], 'after': [2472, 3899], 'Visitwise': [2478], 'ratings': [2485, 3075], 'total,': [2502], 'positive,': [2503], 'At': [2511], 'weeks': [2512, 3810], '3,': [2515, 3309], '(F=4.36,': [2532], 'p=0.04,': [2535], 'F=5.69,': [2537], 'p=0.02,': [2540, 2554, 2559], 'respectively)': [2541], '(F=5.30,': [2551], 'F=5.64,': [2556], 'respectively),': [2560], '(F=4.30,': [2573], 'p=0.04).': [2576], 'comparison': [2578, 3292, 3449], 'group,': [2582], 'show': [2588, 3625], 'visit.Response': [2598], 'responder': [2603, 3143], 'achieving': [2609], 'endpoint.': [2627], 'Significantly': [2628], '(olanzapine:': [2637, 2750, 2973], 'N=34': [2638], '70,': [2640], '48.6%;': [2641], 'placebo:': [2642, 2753, 2975], 'N=16': [2643], '66,': [2645], '24.2%;': [2646], 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'17.6%;': [2974], '0%;': [2976], 'p<0.001,': [2977], 'test).': [2980], 'returned': [2987], 'normal': [2989], 'continued': [2991], 'none': [2996], 'hepatic': [3004], 'dysfunction': [3005], 'time,': [3008], 'observations': [3011], 'earlier': [3013], '(24).ECGThere': [3017], 'ECG': [3036], 'heart': [3037], 'interval': [3040, 3850], 'times.DISCUSSIONThis': [3041], 'placebo-controlled,': [3043], 'suggests': [3046], 'effective': [3050], 'mania,': [3056], 'evidenced': [3058], 'decreases': [3061], 'Version;': [3080], 'percentage': [3097], 'smaller': [3110], '(p=0.02)': [3111], '(28.6%)': [3116], '(47.8%).': [3122], 'That': [3123], 'antimanic': [3127, 3504, 4135], 'further': [3130], 'suggested': [3131], 'magnitude': [3134], 'illustrated': [3140], 'where': [3145, 4169], '48.6%': [3146], 'score,': [3164, 3517], '24.2%': [3167], 'Similar': [3172], 'degrees': [3173], 'recent': [3180, 3425, 3570], '(41,': [3188, 3829], '42).': [3189], 'Bowden': [3190, 3937, 4038, 4165], 'collaborators': [3192, 3248], '(41)': [3193], 'found': [3194, 3260, 4036, 4322], '48%': [3196, 3945], 'divalproex-treated': [3198], '49%': [3201], 'lithium-treated': [3203], '25%': [3207, 4033], '50%.': [3217, 3269], 'subscale': [3225, 3494], 'Schedule': [3228], 'Affective': [3230], 'Disorders': [3231], 'Schizophrenia': [3233], '(43)': [3234], 'instead': [3235], 'assess': [3243, 3257, 3326], 'Pope': [3246, 4079, 4102, 4151], '(42),': [3249, 3964], 'using': [3250], '54%': [3262], 'valproate-treated': [3264], 'improved': [3266], 'Considering': [3270], 'populations': [3278], 'across': [3282], 'studies,': [3283], 'appropriate': [3286], 'would': [3288, 3811], 'head-to-head': [3291], 'against': [3296], 'drugs.Regarding': [3299], 'irritability.': [3333], 'It': [3334, 4083, 4261, 4349], 'reported': [3337, 4077, 4132], 'antipsychotics': [3340, 3562, 3590], 'induce': [3341, 4346], 'maintenance': [3350, 3371, 3470, 3988], '(44,': [3355], '45).': [3356], 'This': [3357, 3908, 4026], 'induction': [3358], 'limits': [3362], 'especially': [3369], 'our': [3374, 3600, 4015, 4122, 4143], 'study,': [3377, 3680, 4168], 'does': [3407, 4344], 'depressogenic': [3410], '(46).': [3422], 'comparing': [3427], '(20),': [3439], 'haloperidol-treated': [3451], 'antidepressant': [3457], 'depression-inducing': [3459], 'can': [3464], 'ascertained': [3467], 'studies.Since': [3471], 'properties,': [3475], 'surprising': [3479, 4352], 'similar': [3519, 4030, 4146, 4173], 'nonpsychotic': [3521], 'patients.Use': [3524], 'remains': [3534], 'controversial.': [3535], 'Although': [3536, 3728], 'well-documented': [3540], '(46–50),': [3541], 'regarding': [3543], 'possible': [3545, 4085, 4113, 4199, 4263], 'raised': [3556], '(51).': [3557], 'Despite': [3558], 'risk,': [3560], 'widely': [3564], 'used,': [3565], 'documented': [3567], 'pharmacoepidemiologic': [3571], '(8)': [3573], '89%': [3579], 'inpatients': [3582], '64%': [3584, 3952], 'outpatients': [3586], 'taking': [3588], 'combination': [3594], 'agents.': [3597], 'found.': [3615], 'small': [3627, 4267], 'developing': [3630], '(52)': [3633], '(53).': [3637], 'extrapolate': [3651], 'Further': [3657, 3995], 'experience': [3661], 'will': [3662], 'help': [3663], 'clarify': [3665], 'role': [3667, 4003], 'development': [3672], 'patients.In': [3678], 'withdrew': [3684], 'event.': [3693], 'Very': [3694], 'few': [3695], 'emerged,': [3698], 'medication': [3703], 'signs,': [3721], 'analyses,': [3723], 'ECGs,': [3724], 'gain,': [3741], 'period;': [3754], 'thus,': [3755], 'important': [3758], 'treating': [3761, 3866], 'clinician': [3762], 'monitor': [3764], 'address': [3766], 'ongoing': [3770], 'basis.There': [3771], 'limitations': [3774], '1)': [3778], 'duration': [3780], '21': [3791, 3833], 'days.': [3792], 'ethical': [3796, 3863, 3888], 'extending': [3805], 'beyond': [3808], 'follow': [3813], 'current': [3814], 'practice.': [3816], 'Other': [3817], 'published': [3818], '42)': [3830], 'length': [3837], 'treatment;': [3839], 'therefore,': [3840], 'reasonable': [3848], 'balance': [3852], 'drug': [3860], 'suffering': [3868], '2)': [3875], 'dropout': [3880, 3915, 3942, 3966], 'Again,': [3886], 'reasons,': [3889], 'order': [3903], 'start': [3905], 'contributed': [3911], 'rate,': [3916], '65.2%': [3920], '38.6%': [3927], 'Similarly,': [3932], 'et': [3938, 4040, 4052, 4103, 4152, 4166], 'al.': [3939, 4041, 4053, 4104, 4153, 4167], '(41),': [3940, 4042], 'rates': [3943, 3967], 'divalproex,': [3947, 4045], '61%': [3948], 'similarly': [3961], 'designed': [3962], '76%': [3969], 'valproate': [3971], '79%': [3973], '3)': [3976], 'information': [3978], 'provided': [3991, 4253], 'determine': [4001], 'long-term': [4007], '4)': [4012], 'Janicak': [4051], '(54),': [4054], 'clonidine': [4057], 'mania;': [4065], 'however,': [4066], '5%': [4073], 'colleagues': [4081], '(42).': [4082], 'less': [4106], 'explanation': [4114, 4200], '(55).': [4137], '(4': [4155], 'contrast,': [4162], '(25%': [4176], 'subjects),': [4178], 'lorazepam': [4179], '(2': [4185], 'then': [4192], '5–10).': [4197], 'requirement': [4210], 'inpatient': [4212, 4258], 'week.': [4218], 'Hospitalization': [4219], 'itself': [4221], 'provides': [4222], 'reducing': [4225], 'sensory': [4229], 'stimulation': [4230], 'under': [4231], 'care': [4233], 'health': [4235], 'professionals': [4236], '(6).': [4237], 'even': [4239], 'part': [4240, 4273], 'patients’': [4244], 'attributed': [4248], 'structured': [4251], 'environment': [4252], 'trial.': [4260], 'recovery': [4271], 'natural': [4276], 'illness,': [4279], 'explain': [4282], 'portion': [4284], 'response.Although': [4288], 'scale,': [4292], 'scales.': [4317], 'ratings,': [4336], 'unlike': [4339], 'between-group': [4357], 'b': [4378]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2109442247', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 6}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 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