Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2109334984', 'doi': 'https://doi.org/10.1016/j.cmpb.2009.11.001', 'title': 'Assessing erectile neurogenic dysfunction from heart rate variability through a Generalized Linear Mixed Model framework', 'display_name': 'Assessing erectile neurogenic dysfunction from heart rate variability through a Generalized Linear Mixed Model framework', 'publication_year': 2009, 'publication_date': '2009-12-17', 'ids': {'openalex': 'https://openalex.org/W2109334984', 'doi': 'https://doi.org/10.1016/j.cmpb.2009.11.001', 'mag': '2109334984', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20015570'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cmpb.2009.11.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S138959710', 'display_name': 'Computer Methods and Programs in Biomedicine', 'issn_l': '0169-2607', 'issn': ['0169-2607', '1872-7565'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5022933882', 'display_name': 'Elmer Fernández', 'orcid': 'https://orcid.org/0000-0002-4711-8634'}, 'institutions': [{'id': 'https://openalex.org/I130054616', 'display_name': 'Universidad Católica de Córdoba', 'ror': 'https://ror.org/04hehwn14', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I130054616']}, {'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}], 'countries': ['AR'], 'is_corresponding': True, 'raw_author_name': 'Elmer Andrés Fernández', 'raw_affiliation_strings': ['CONICET, Argentina', 'Facultad de Ingeniería, Universidad Católica de Córdoba, Obispo Trejo 323, X5000IYG Córdoba, Argentina'], 'affiliations': [{'raw_affiliation_string': 'Facultad de Ingeniería, Universidad Católica de Córdoba, Obispo Trejo 323, X5000IYG Córdoba, Argentina', 'institution_ids': ['https://openalex.org/I130054616']}, {'raw_affiliation_string': 'CONICET, Argentina', 'institution_ids': ['https://openalex.org/I151201029']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068951569', 'display_name': 'E P Souza Neto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210105768', 'display_name': 'Hôpital Pierre Wertheimer', 'ror': 'https://ror.org/01q046q46', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210105768']}, {'id': 'https://openalex.org/I4210100596', 'display_name': 'Hospices Civils de Lyon', 'ror': 'https://ror.org/01502ca60', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596']}, {'id': 'https://openalex.org/I100532134', 'display_name': 'Université Claude Bernard Lyon 1', 'ror': 'https://ror.org/029brtt94', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I100532134', 'https://openalex.org/I203339264']}, {'id': 'https://openalex.org/I4210123600', 'display_name': 'Hôpital Edouard Herriot', 'ror': 'https://ror.org/02qt1p572', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210123600']}, {'id': 'https://openalex.org/I113428412', 'display_name': 'École Normale Supérieure de Lyon', 'ror': 'https://ror.org/04zmssz18', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I113428412', 'https://openalex.org/I203339264']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'E.P. Souza Neto', 'raw_affiliation_strings': ["CNRS, Laboratoire de Physique, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France", "Hospices Civils de Lyon, Groupement Hospitalier Est, Hôpital Neurologique Pierre Wertheimer, Service d'Anesthésie Réanimation, 59 boulevard Pinel, 69677 Bron Cedex, France", "Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France"], 'affiliations': [{'raw_affiliation_string': "Hospices Civils de Lyon, Groupement Hospitalier Est, Hôpital Neurologique Pierre Wertheimer, Service d'Anesthésie Réanimation, 59 boulevard Pinel, 69677 Bron Cedex, France", 'institution_ids': ['https://openalex.org/I4210105768', 'https://openalex.org/I4210100596']}, {'raw_affiliation_string': "Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France", 'institution_ids': ['https://openalex.org/I100532134', 'https://openalex.org/I4210123600']}, {'raw_affiliation_string': "CNRS, Laboratoire de Physique, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France", 'institution_ids': ['https://openalex.org/I113428412', 'https://openalex.org/I1294671590']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050643672', 'display_name': 'Patrice Abry', 'orcid': 'https://orcid.org/0000-0002-7096-8290'}, 'institutions': [{'id': 'https://openalex.org/I113428412', 'display_name': 'École Normale Supérieure de Lyon', 'ror': 'https://ror.org/04zmssz18', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I113428412', 'https://openalex.org/I203339264']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'P. Abry', 'raw_affiliation_strings': ["CNRS, Laboratoire de Physique, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France"], 'affiliations': [{'raw_affiliation_string': "CNRS, Laboratoire de Physique, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France", 'institution_ids': ['https://openalex.org/I113428412', 'https://openalex.org/I1294671590']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000826941', 'display_name': 'Raúl Macchiavelli', 'orcid': 'https://orcid.org/0000-0002-3727-6874'}, 'institutions': [{'id': 'https://openalex.org/I60388903', 'display_name': 'University of Puerto Rico-Mayaguez', 'ror': 'https://ror.org/00wek6x04', 'country_code': 'PR', 'type': 'education', 'lineage': ['https://openalex.org/I200399037', 'https://openalex.org/I60388903']}], 'countries': ['PR'], 'is_corresponding': False, 'raw_author_name': 'R. Macchiavelli', 'raw_affiliation_strings': ['University of Puerto Rico, Mayaguez, Puerto Rico'], 'affiliations': [{'raw_affiliation_string': 'University of Puerto Rico, Mayaguez, Puerto Rico', 'institution_ids': ['https://openalex.org/I60388903']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088484639', 'display_name': 'Mónica Balzarini', 'orcid': 'https://orcid.org/0000-0002-4858-4637'}, 'institutions': [{'id': 'https://openalex.org/I151201029', 'display_name': 'Consejo Nacional de Investigaciones Científicas y Técnicas', 'ror': 'https://ror.org/03cqe8w59', 'country_code': 'AR', 'type': 'government', 'lineage': ['https://openalex.org/I151201029', 'https://openalex.org/I4210123736', 'https://openalex.org/I4387155568']}, {'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'M. Balzarini', 'raw_affiliation_strings': ['CONICET, Argentina', 'National University of Cordoba, Biometric Department, Argentina'], 'affiliations': [{'raw_affiliation_string': 'CONICET, Argentina', 'institution_ids': ['https://openalex.org/I151201029']}, {'raw_affiliation_string': 'National University of Cordoba, Biometric Department, Argentina', 'institution_ids': ['https://openalex.org/I166401450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061799034', 'display_name': 'B. Cuzin', 'orcid': 'https://orcid.org/0000-0002-1717-0407'}, 'institutions': [{'id': 'https://openalex.org/I166401450', 'display_name': 'Universidad Nacional de Córdoba', 'ror': 'https://ror.org/056tb7j80', 'country_code': 'AR', 'type': 'education', 'lineage': ['https://openalex.org/I166401450']}], 'countries': ['AR'], 'is_corresponding': False, 'raw_author_name': 'B. Cuzin', 'raw_affiliation_strings': ['National University of Cordoba, Biometric Department, Argentina'], 'affiliations': [{'raw_affiliation_string': 'National University of Cordoba, Biometric Department, Argentina', 'institution_ids': ['https://openalex.org/I166401450']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018677738', 'display_name': 'C. Baude', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210123600', 'display_name': 'Hôpital Edouard Herriot', 'ror': 'https://ror.org/02qt1p572', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210123600']}, {'id': 'https://openalex.org/I4210100596', 'display_name': 'Hospices Civils de Lyon', 'ror': 'https://ror.org/01502ca60', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'C. Baude', 'raw_affiliation_strings': ["Hospices Civils de Lyon, Hôpital Edouard Herriot, Service d'Urologie et Chirurgie de la Transplantation, 5 place d'Arsonval, 69437 Lyon Cedex 03, France"], 'affiliations': [{'raw_affiliation_string': "Hospices Civils de Lyon, Hôpital Edouard Herriot, Service d'Urologie et Chirurgie de la Transplantation, 5 place d'Arsonval, 69437 Lyon Cedex 03, France", 'institution_ids': ['https://openalex.org/I4210123600', 'https://openalex.org/I4210100596']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042052171', 'display_name': 'J. Frutoso', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100532134', 'display_name': 'Université Claude Bernard Lyon 1', 'ror': 'https://ror.org/029brtt94', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I100532134', 'https://openalex.org/I203339264']}, {'id': 'https://openalex.org/I4210123600', 'display_name': 'Hôpital Edouard Herriot', 'ror': 'https://ror.org/02qt1p572', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210123600']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J. Frutoso', 'raw_affiliation_strings': ["Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France"], 'affiliations': [{'raw_affiliation_string': "Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France", 'institution_ids': ['https://openalex.org/I100532134', 'https://openalex.org/I4210123600']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013536715', 'display_name': 'C Gharib', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I100532134', 'display_name': 'Université Claude Bernard Lyon 1', 'ror': 'https://ror.org/029brtt94', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I100532134', 'https://openalex.org/I203339264']}, {'id': 'https://openalex.org/I4210123600', 'display_name': 'Hôpital Edouard Herriot', 'ror': 'https://ror.org/02qt1p572', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210100596', 'https://openalex.org/I4210123600']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'C. Gharib', 'raw_affiliation_strings': ["Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France"], 'affiliations': [{'raw_affiliation_string': "Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, Université Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France", 'institution_ids': ['https://openalex.org/I100532134', 'https://openalex.org/I4210123600']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 10, 'corresponding_author_ids': ['https://openalex.org/A5022933882'], 'corresponding_institution_ids': ['https://openalex.org/I130054616', 'https://openalex.org/I151201029'], 'apc_list': {'value': 2880, 'currency': 'USD', 'value_usd': 2880, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.306, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.784209, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '99', 'issue': '1', 'first_page': '49', 'last_page': '56'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10745', 'display_name': 'Analysis and Applications of Heart Rate Variability', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10745', 'display_name': 'Analysis and Applications of Heart Rate Variability', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13381', 'display_name': 'Impact of Resting Heart Rate on Cardiovascular Health', 'score': 0.9762, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10144', 'display_name': 'Management of Hypertension and Cardiovascular Risk Factors', 'score': 0.9479, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/heart-rate-variability', 'display_name': 'Heart Rate Variability', 'score': 0.587791}, {'id': 'https://openalex.org/keywords/resting-heart-rate', 'display_name': 'Resting Heart Rate', 'score': 0.553436}, {'id': 'https://openalex.org/keywords/mixed-model', 'display_name': 'Mixed model', 'score': 0.55143785}, {'id': 'https://openalex.org/keywords/heartbeat-classification', 'display_name': 'Heartbeat Classification', 'score': 0.548179}, {'id': 'https://openalex.org/keywords/arrhythmia-detection', 'display_name': 'Arrhythmia Detection', 'score': 0.529946}], 'concepts': [{'id': 'https://openalex.org/C153720581', 'wikidata': 'https://www.wikidata.org/wiki/Q5532490', 'display_name': 'Generalized linear mixed model', 'level': 2, 'score': 0.6342792}, {'id': 'https://openalex.org/C101104100', 'wikidata': 'https://www.wikidata.org/wiki/Q1063540', 'display_name': 'Heteroscedasticity', 'level': 2, 'score': 0.5832423}, {'id': 'https://openalex.org/C168743327', 'wikidata': 'https://www.wikidata.org/wiki/Q1826427', 'display_name': 'Random effects model', 'level': 3, 'score': 0.5626973}, {'id': 'https://openalex.org/C16012445', 'wikidata': 'https://www.wikidata.org/wiki/Q1501135', 'display_name': 'Mixed model', 'level': 2, 'score': 0.55143785}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.5434736}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.5407631}, {'id': 'https://openalex.org/C87007009', 'wikidata': 'https://www.wikidata.org/wiki/Q210832', 'display_name': 'Statistical hypothesis testing', 'level': 2, 'score': 0.46987942}, {'id': 'https://openalex.org/C40696583', 'wikidata': 'https://www.wikidata.org/wiki/Q989120', 'display_name': 'Type I and type II errors', 'level': 2, 'score': 0.46282774}, {'id': 'https://openalex.org/C163716315', 'wikidata': 'https://www.wikidata.org/wiki/Q901177', 'display_name': 'Gaussian', 'level': 2, 'score': 0.46096346}, {'id': 'https://openalex.org/C117220453', 'wikidata': 'https://www.wikidata.org/wiki/Q5172842', 'display_name': 'Correlation', 'level': 2, 'score': 0.43274146}, {'id': 'https://openalex.org/C102366305', 'wikidata': 'https://www.wikidata.org/wiki/Q1097688', 'display_name': 'Nonparametric statistics', 'level': 2, 'score': 0.42825046}, {'id': 'https://openalex.org/C2779929075', 'wikidata': 'https://www.wikidata.org/wiki/Q184674', 'display_name': 'Erectile dysfunction', 'level': 2, 'score': 0.4212263}, {'id': 'https://openalex.org/C163175372', 'wikidata': 'https://www.wikidata.org/wiki/Q3339222', 'display_name': 'Linear model', 'level': 2, 'score': 0.41664922}, {'id': 'https://openalex.org/C102094743', 'wikidata': 'https://www.wikidata.org/wiki/Q133871', 'display_name': 'Normal distribution', 'level': 2, 'score': 0.411788}, {'id': 'https://openalex.org/C149782125', 'wikidata': 'https://www.wikidata.org/wiki/Q160039', 'display_name': 'Econometrics', 'level': 1, 'score': 0.33556962}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25897682}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.22383371}, {'id': 'https://openalex.org/C95190672', 'wikidata': 'https://www.wikidata.org/wiki/Q815382', 'display_name': 'Meta-analysis', 'level': 2, 'score': 0.16521302}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0859822}, {'id': 'https://openalex.org/C2524010', 'wikidata': 'https://www.wikidata.org/wiki/Q8087', 'display_name': 'Geometry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007172', 'descriptor_name': 'Erectile Dysfunction', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D006339', 'descriptor_name': 'Heart Rate', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D001341', 'descriptor_name': 'Autonomic Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001341', 'descriptor_name': 'Autonomic Nervous System', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D004562', 'descriptor_name': 'Electrocardiography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007172', 'descriptor_name': 'Erectile Dysfunction', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D007172', 'descriptor_name': 'Erectile Dysfunction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006339', 'descriptor_name': 'Heart Rate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016014', 'descriptor_name': 'Linear Models', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.cmpb.2009.11.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S138959710', 'display_name': 'Computer Methods and Programs in Biomedicine', 'issn_l': '0169-2607', 'issn': ['0169-2607', '1872-7565'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20015570', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.56, 'id': 'https://metadata.un.org/sdg/7', 'display_name': 'Affordable and clean energy'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W103650626', 'https://openalex.org/W114854541', 'https://openalex.org/W116067051', 'https://openalex.org/W1526182533', 'https://openalex.org/W1528905581', 'https://openalex.org/W1987766467', 'https://openalex.org/W1995583461', 'https://openalex.org/W2000084758', 'https://openalex.org/W2025918426', 'https://openalex.org/W2039799534', 'https://openalex.org/W2050487954', 'https://openalex.org/W2062618262', 'https://openalex.org/W2075331240', 'https://openalex.org/W2092875573', 'https://openalex.org/W2110463769', 'https://openalex.org/W2112233738', 'https://openalex.org/W2125109199', 'https://openalex.org/W2133589238', 'https://openalex.org/W2142045810', 'https://openalex.org/W2285072859', 'https://openalex.org/W2400758447', 'https://openalex.org/W2734548225', 'https://openalex.org/W3015238844', 'https://openalex.org/W386847987', 'https://openalex.org/W4285719527', 'https://openalex.org/W4292914396', 'https://openalex.org/W623109190', 'https://openalex.org/W643529837'], 'related_works': ['https://openalex.org/W4307324678', 'https://openalex.org/W4289422681', 'https://openalex.org/W4239710992', 'https://openalex.org/W2953058310', 'https://openalex.org/W2895736713', 'https://openalex.org/W225107685', 'https://openalex.org/W2082190293', 'https://openalex.org/W2021312236', 'https://openalex.org/W1988055263', 'https://openalex.org/W1551599973'], 'abstract_inverted_index': {'The': [0, 32, 101, 234, 286], 'low': [1], '(LF)': [2], 'vs.': [3], 'high': [4], '(HF)': [5], 'frequency': [6], 'energy': [7], 'ratio,': [8, 48], 'computed': [9], 'from': [10, 39, 56, 97, 172, 273], 'the': [11, 46, 61, 68, 75, 98, 109, 124, 128, 131, 155, 164, 173, 187, 191, 198, 241, 274, 283, 311, 315, 318], 'spectral': [12], 'decomposition': [13], 'of': [14, 35, 41, 60, 106, 111, 130, 143, 148, 157, 205, 224, 295, 317], 'heart': [15], 'beat': [16], 'intervals,': [17], 'has': [18], 'become': [19], 'a': [20, 57, 65, 118, 219, 225, 290, 296, 300], 'major': [21], 'tool': [22], 'in': [23, 218], 'cardiac': [24], 'autonomic': [25], 'system': [26], 'control': [27], 'and': [28, 83, 193, 229, 251, 259, 314, 325], 'sympatho–vagal': [29, 199], 'balance': [30, 200], 'studies.': [31], '(statistical)': [33], 'distributions': [34], 'response': [36, 297], 'variables': [37], 'designed': [38], 'ratios': [40], 'two': [42], 'quantities,': [43], 'such': [44, 85, 104], 'as': [45, 74, 86, 202, 299], 'LF/HF': [47, 203], 'are': [49, 95, 329], 'likely': [50], 'to': [51, 138, 282], 'non-normal,': [52], 'hence': [53], 'preventing': [54], 'e.g.,': [55], 'relevant': [58], 'use': [59, 129], 't-test.': [62], 'Even': [63], 'using': [64, 178, 249], 'non-parametric': [66], 'formulation,': [67], 'solution': [69], 'may': [70], 'be': [71, 90], 'not': [72, 79, 116], 'appropriate': [73], 'test': [76], 'statistics': [77], 'do': [78, 115], 'account': [80], 'for': [81, 103, 190, 266], 'correlation': [82, 169], 'heteroskedasticity,': [84], 'those': [87], 'that': [88], 'can': [89], 'observed': [91], 'when': [92], 'several': [93], 'measures': [94, 144], 'taken': [96], 'same': [99, 174, 275], 'patient.': [100], 'analyses': [102], 'type': [105], 'data': [107, 319, 322], 'require': [108], 'application': [110], 'statistical': [112], 'models': [113, 153, 307], 'which': [114, 167], 'assume': [117, 182], 'priori': [119], 'independence.': [120], 'In': [121], 'this': [122], 'spirit,': [123], 'present': [125], 'contribution': [126], 'proposes': [127], 'Generalized': [132], 'Linear': [133], 'Mixed': [134], 'Models': [135], '(GLMMs)': [136], 'framework': [137], 'assess': [139], 'differences': [140], 'between': [141, 170, 271, 310], 'groups': [142], 'performed': [145], 'over': [146], 'classes': [147], 'patients.': [149], 'Statistical': [150], 'linear': [151, 243], 'mixed': [152, 244], 'allow': [154, 263], 'inclusion': [156], 'at': [158], 'least': [159], 'one': [160], 'random': [161], 'effect,': [162], 'besides': [163], 'error': [165], 'term,': [166], 'induces': [168], 'observations': [171, 272], 'subject.': [175], 'Moreover,': [176], 'by': [177, 222], 'GLMM,': [179], 'practitioners': [180], 'could': [181], 'any': [183], 'probability': [184], 'distribution,': [185], 'within': [186], 'exponential': [188], 'family,': [189], 'data,': [192], 'naturally': [194], 'model': [195, 237, 245], 'heteroskedasticity.': [196], 'Here,': [197], 'expressed': [201, 298], 'ratio': [204], 'patients': [206], 'suffering': [207], 'neurogenic': [208], 'erectile': [209], 'dysfunction': [210], 'under': [211, 227, 277], 'three': [212], 'different': [213, 278], 'body': [214, 279], 'positions': [215], 'was': [216, 238], 'analyzed': [217], 'case–control': [220], 'protocol': [221], 'means': [223], 'GLMM': [226, 236, 257, 288], 'gamma': [228, 235, 258, 287, 303], 'Gaussian': [230], 'distributed': [231], 'responses': [232], 'assumptions.': [233], 'compared': [239, 281], 'with': [240], 'normal': [242], '(LMM)': [246], 'approach': [247], 'conducted': [248], 'raw': [250, 256, 284], 'log': [252, 260], 'transformed': [253, 261], 'data.': [254], 'Both': [255], 'LMM': [262], 'better': [264], 'inference': [265], 'factor': [267], 'effects,': [268], 'including': [269], 'correlations': [270], 'patient': [276], 'position': [280], 'LMM.': [285], 'provides': [289], 'more': [291], 'natural': [292], 'distribution': [293, 304], 'assumption': [294, 305], 'ratio.': [301], 'A': [302], 'intrinsically': [306], 'quadratic': [308], 'relationships': [309], 'expected': [312], 'value': [313], 'variance': [316], 'avoiding': [320], 'prior': [321], 'transformation.': [323], 'SAS': [324], 'R': [326], 'source': [327], 'code': [328], 'available': [330], 'on': [331], 'request.': [332]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2109334984', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-09-11T04:04:35.139487', 'created_date': '2016-06-24'}