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376, 389, 394, 446, 459, 481, 489, 502, 508, 510, 536, 563, 593, 609, 630, 643, 722, 748, 765, 808, 823, 852, 947, 960, 1076, 1177, 1239, 1298, 1326, 1329, 1337, 1373, 1388, 1471, 1492, 1512, 1580, 1589, 1629, 1745, 1753, 1769, 1795, 1808, 1831, 1875, 1879, 1890, 1895, 1928, 1936, 1957, 2026, 2072, 2119, 2129, 2143, 2157, 2167, 2255, 2261, 2305, 2368, 2370, 2384, 2395, 2426, 2478, 2524, 2541, 2594, 2615, 2659, 2675, 2682, 2700, 2714, 2910, 2931, 2996, 3000, 3021, 3062, 3075, 3090, 3099, 3126, 3139, 3162, 3188, 3192, 3199, 3225, 3230, 3260, 3279, 3311, 3331, 3336, 3387, 3395, 3410, 3429, 3469, 3483, 3488, 3526, 3582, 3626, 3643, 3659, 3714, 3725, 3770, 3781, 3793, 3808, 3876, 3887, 3955, 4120, 4205, 4240, 4242, 4295, 4309, 4317, 4406, 4461, 4490, 4498, 4520, 4536, 4550, 4585], 'knowledge': [3, 103, 3298, 3409], 'of': [4, 8, 16, 34, 44, 57, 70, 87, 97, 104, 121, 135, 166, 215, 227, 252, 262, 266, 275, 318, 379, 385, 405, 412, 452, 479, 492, 514, 539, 561, 566, 582, 596, 599, 617, 628, 637, 664, 671, 725, 739, 754, 771, 832, 855, 858, 935, 956, 966, 988, 997, 1013, 1016, 1032, 1039, 1050, 1059, 1067, 1085, 1088, 1100, 1103, 1118, 1121, 1181, 1220, 1241, 1272, 1292, 1295, 1335, 1385, 1403, 1421, 1449, 1474, 1495, 1515, 1552, 1576, 1592, 1612, 1618, 1632, 1638, 1667, 1678, 1687, 1696, 1722, 1748, 1751, 1775, 1804, 1826, 1857, 1868, 1923, 1940, 1950, 2002, 2011, 2047, 2060, 2092, 2116, 2123, 2160, 2170, 2211, 2214, 2232, 2243, 2270, 2334, 2340, 2348, 2387, 2481, 2498, 2530, 2534, 2583, 2599, 2608, 2613, 2646, 2651, 2670, 2673, 2688, 2693, 2703, 2721, 2740, 2743, 2752, 2768, 2777, 2824, 2866, 2899, 2987, 2990, 3025, 3059, 3065, 3079, 3093, 3106, 3221, 3252, 3263, 3276, 3282, 3322, 3325, 3339, 3381, 3393, 3397, 3423, 3435, 3456, 3463, 3467, 3492, 3496, 3529, 3546, 3611, 3622, 3632, 3686, 3731, 3736, 3749, 3758, 3798, 3812, 3834, 3840, 3860, 3874, 3909, 3924, 3979, 3982, 4016, 4091, 4154, 4166, 4209, 4236, 4251, 4257, 4298, 4334, 4345, 4358, 4384, 4436, 4441, 4464, 4486, 4509, 4554, 4563, 4593], 'the': [5, 14, 23, 35, 45, 48, 53, 62, 71, 98, 105, 115, 119, 122, 147, 151, 164, 167, 169, 213, 216, 228, 240, 245, 253, 263, 273, 295, 316, 319, 355, 377, 392, 403, 443, 450, 453, 477, 482, 487, 490, 493, 499, 511, 515, 545, 559, 564, 580, 585, 594, 614, 626, 634, 644, 665, 723, 731, 749, 833, 835, 853, 863, 882, 911, 926, 933, 951, 985, 1001, 1111, 1131, 1187, 1203, 1226, 1293, 1308, 1327, 1339, 1355, 1376, 1383, 1386, 1392, 1404, 1487, 1500, 1525, 1543, 1550, 1574, 1596, 1624, 1651, 1668, 1740, 1746, 1762, 1843, 1869, 1893, 1897, 1904, 1929, 1948, 1951, 1963, 1972, 1992, 2009, 2028, 2045, 2066, 2093, 2104, 2114, 2130, 2137, 2150, 2158, 2168, 2179, 2209, 2230, 2240, 2268, 2277, 2284, 2293, 2297, 2302, 2322, 2337, 2341, 2345, 2385, 2388, 2393, 2396, 2406, 2416, 2423, 2479, 2482, 2536, 2595, 2600, 2616, 2671, 2683, 2701, 2719, 2772, 2802, 2858, 2867, 2877, 2911, 2988, 3013, 3022, 3046, 3076, 3080, 3091, 3127, 3176, 3222, 3241, 3261, 3280, 3308, 3312, 3323, 3332, 3366, 3379, 3391, 3450, 3464, 3489, 3494, 3515, 3544, 3562, 3577, 3605, 3620, 3647, 3695, 3723, 3728, 3747, 3750, 3756, 3759, 3768, 3803, 3809, 3824, 3829, 3832, 3852, 3858, 3866, 3885, 3907, 3910, 3935, 3946, 3956, 3972, 3977, 4001, 4014, 4019, 4055, 4057, 4081, 4089, 4099, 4106, 4112, 4121, 4124, 4129, 4146, 4152, 4155, 4164, 4206, 4225, 4249, 4300, 4332, 4335, 4346, 4381, 4393, 4409, 4422, 4431, 4487, 4503, 4600], 'scientific': [6], 'basis': [7], 'disease': [9, 69, 673, 1305, 4021], 'and': [10, 55, 75, 94, 118, 184, 187, 199, 234, 341, 367, 475, 484, 496, 523, 552, 622, 659, 681, 706, 778, 821, 915, 1023, 1062, 1171, 1207, 1282, 1303, 1310, 1348, 1443, 1528, 1659, 1690, 1733, 1738, 1781, 1793, 1806, 1818, 1915, 1995, 2042, 2076, 2162, 2175, 2202, 2354, 2377, 2421, 2489, 2518, 2558, 2576, 2642, 2729, 2792, 2797, 2852, 2919, 2969, 2978, 2994, 3006, 3117, 3166, 3245, 3273, 3369, 3426, 3460, 3595, 3599, 3637, 3654, 3662, 3693, 3718, 3734, 3754, 3952, 4051, 4115, 4311, 4313, 4322, 4368, 4375, 4425, 4475, 4573, 4603], 'consequent': [11], 'advances': [12, 101], 'practice': [15], 'medicine': [17, 2101], 'that': [18, 51, 110, 196, 239, 249, 284, 307, 338, 348, 402, 411, 466, 518, 530, 575, 660, 697, 711, 845, 865, 953, 1010, 1216, 1372, 1467, 1486, 1623, 1675, 1719, 1739, 1764, 1862, 1931, 2083, 2106, 2132, 2148, 2190, 2208, 2276, 2296, 2309, 2410, 2422, 2459, 2512, 2526, 2632, 2656, 2735, 2801, 2842, 2856, 3035, 3179, 3306, 3318, 3416, 3421, 3505, 3517, 3543, 3561, 3639, 3652, 3663, 3678, 3694, 3707, 3735, 3767, 3773, 3828, 3914, 3971, 4043, 4145, 4163, 4229, 4288, 4351, 4392, 4484, 4534, 4552, 4590, 4604], 'have': [19, 26, 39, 111, 370, 1228, 1412, 1918, 1944, 2136, 2252, 2266, 2365, 2567, 2571, 2805, 2905, 2929, 2961, 3082, 3375, 4190, 4413], 'taken': [20, 2128], 'place': [21], 'past': [24, 1205, 1227], 'century': [25, 517, 3081], 'been': [27, 40, 112, 371, 611, 640, 654, 763, 828, 950, 1020, 1125, 1138, 1229, 1345, 1480, 1490, 1599, 1627, 1649, 1743, 1759, 1813, 1840, 1873, 1885, 1900, 1919, 1955, 2087, 2145, 2220, 2235, 2253, 2366, 2419, 2442, 2514, 2568, 2590, 2806, 2907, 3084, 3131, 3212, 3271, 3376, 3554, 3580, 3927, 3997, 4247, 4526, 4541, 4581], 'truly': [28], 'remarkable.': [29], 'This': [30, 1871, 2812, 3590], 'is': [31, 91, 409, 424, 884, 913, 1264, 1287, 1332, 1458, 1507, 1654, 2080, 2521, 2870, 2883, 3039, 3044, 3048, 3058, 3135], 'certainly': [32], 'true': [33, 1397, 1874], 'haemolytic': [36, 66, 68, 108, 396, 422, 601, 745, 859, 867, 1296, 1377, 1540, 1645, 1829, 2024, 2390, 2499, 2850, 2862, 2893, 2970, 3031, 3066, 3190, 3228, 3288, 3327, 3401, 3437, 3441, 3470, 3531, 3732, 4259], 'anaemias,': [37, 67, 397, 3191, 3438], 'which': [38, 638, 766, 824, 888, 898, 1134, 1796, 1896, 2233, 2440, 3033, 3100, 3267, 3388, 3443, 3921, 4023, 4105, 4128, 4521, 4537], 'a': [41, 127, 201, 439, 533, 591, 692, 751, 767, 800, 809, 963, 1077, 1119, 1199, 1211, 1217, 1249, 1269, 1324, 1453, 1513, 1577, 1609, 1616, 1685, 1754, 1773, 1937, 1961, 2061, 2120, 2246, 2307, 2310, 2332, 2351, 2356, 2414, 2446, 2496, 2502, 2527, 2640, 2704, 2749, 2946, 3026, 3055, 3156, 3185, 3196, 3219, 3293, 3480, 3497, 3523, 3818, 3930, 4025, 4171, 4191, 4230, 4252, 4258, 4292, 4296, 4314, 4417, 4426, 4522], 'main': [42, 2250], 'interest': [43, 2126, 3594, 3903], 'author': [46, 1671, 1715, 1784, 2033, 2223, 2506, 2628, 2950, 3825], 'since': [47, 1761, 1842, 2906], 'mid-1930s.': [49], 'At': [50, 195, 543], 'time,': [52, 197, 547, 3307], 'cause': [54, 979, 2242, 2497], 'mechanism': [56, 627, 3521], 'important': [58, 850, 945, 1193, 2328, 2716, 3295, 3465], 'disorders': [59, 968, 1132, 1281], 'such': [60, 1712, 1798, 2306, 2997], 'as': [61, 211, 333, 811, 813, 910, 971, 973, 1096, 1127, 1140, 2237, 2288, 2553, 2555, 2965, 2967, 2973, 3170, 3218, 3243, 4398, 4518], 'acquired': [63, 106, 420, 600, 2849, 2861, 3030, 3189, 3326, 3400, 3530, 3550], 'antibody-determined': [64], '(immune)': [65], 'newborn,': [72], 'hereditary': [73, 395, 399], 'spherocytosis': [74, 400, 3180], 'paroxysmal': [76, 631], 'nocturnal': [77], 'haemoglobinuria': [78, 779], 'were': [79, 209, 343, 717, 780, 1042, 1091, 1097, 1582, 1800, 1998, 2019, 2058, 2070, 2178, 2411, 2425, 2491, 2685, 2787, 2830, 3168, 3335, 3362, 3428, 3506, 3511, 3657, 3801, 3915, 3960, 4046, 4062, 4268, 4327, 4360, 4396, 4403, 4454, 4459, 4493, 4528, 4557, 4570], 'unknown': [80, 755], 'or': [81, 203, 461, 876, 895, 1558, 1837, 2095, 2245, 2279, 2463, 2737, 2754, 2891, 3037, 3452, 3567, 3944, 3959], 'but': [82, 278, 906, 938, 1320, 2623, 4086, 4136], 'partially': [83], 'understood.': [84], 'purpose': [86], 'this': [88, 604, 1468, 2475, 3217], 'short': [89], 'review': [90, 225, 795, 1078, 1180, 1219], 'to': [92, 130, 149, 154, 212, 291, 314, 391, 416, 448, 456, 473, 719, 803, 816, 838, 862, 880, 990, 1093, 1196, 1209, 1267, 1350, 1381, 1395, 1411, 1510, 1710, 1887, 1943, 1982, 2055, 2098, 2113, 2182, 2257, 2265, 2289, 2434, 2444, 2469, 2494, 2538, 2570, 2593, 2655, 2665, 2928, 3054, 3183, 3194, 3266, 3291, 3297, 3305, 3361, 3374, 3512, 3646, 3701, 3722, 3745, 3844, 3883, 3920, 3965, 3999, 4006, 4065, 4069, 4151, 4170, 4213, 4329, 4353, 4412, 4511, 4531, 4547, 4568, 4587], 'record': [93], 'highlight': [95], 'some': [96, 537, 597, 669, 856, 1374, 1958, 2262, 2427, 2565, 3475, 3527, 4605], 'most': [99, 2621, 3136, 3294], 'significant': [100, 1938, 2121, 2548], 'immune': [107, 421, 577, 1166, 1283, 1776, 2285, 2291, 2313, 2389, 3268, 3520], 'anaemias': [109, 2391], 'made': [113, 4224], 'between': [114, 819, 1731, 1791, 2040, 2516, 2848, 3727, 3948], 'first': [116, 148, 512, 1521, 1968, 2432, 3077], 'decade': [117, 202, 513, 3078], 'end': [120], 'twentieth': [123, 516], 'century.': [124, 646], 'First,': [125], 'however,': [126, 198, 696, 1391, 1640, 1653, 2082, 2474, 2620, 2663, 2709, 3211, 4161, 4516], 'diversion.': [128], 'According': [129, 1981, 4005, 4068], 'Crosby': [131, 2915], '(1952),': [132], 'William': [133], 'Hunter': [134], 'London,': [136], 'an': [138, 156, 334, 419, 661, 849, 1178, 1234, 1288, 1459, 2327, 2457, 2694, 2715, 2761, 3029, 3411, 3457, 3518, 3557, 3633, 3784, 4275], 'article': [139], 'on': [140, 625, 796, 932, 940, 984, 994, 1573, 2283, 2876, 3357, 3755, 3831, 3906, 4098, 4331], 'pernicious': [141, 2727], 'anaemia': [142, 157, 423, 860, 868, 1297, 1378, 1541, 1830, 2500, 2728, 2851, 2863, 3032, 3229, 3289, 3328, 3471, 3532, 3733, 4260], 'published': [143, 818, 1790, 2039, 2668, 3074, 3089], '1888,': [145], 'was': [146, 171, 248, 256, 260, 306, 309, 468, 507, 532, 674, 689, 699, 799, 1074, 1195, 1365, 1370, 1504, 1861, 1927, 1933, 1965, 1971, 2008, 2030, 2127, 2275, 2295, 2392, 2402, 2437, 2799, 2814, 2925, 3102, 3173, 3181, 3317, 3418, 3472, 3533, 3574, 3596, 3743, 3780, 3817, 3847, 3854, 3868, 3881, 3904, 3945, 4198, 4277, 4304, 4307, 4387, 4390], 'use': [150, 2231], 'term': [152, 170, 3015], "'haemolytic'": [153], 'denote': [155], 'caused': [158, 2267, 3448], 'by': [159, 179, 192, 271, 470, 613, 656, 676, 683, 701, 925, 1045, 1555, 1584, 1815, 1960, 2316, 2405, 2471, 2501, 2817, 2902, 2914, 2975, 3003, 3071, 3123, 3233, 3254, 3449, 3477, 3503, 3536, 3556, 3601, 3630, 3689, 3870, 3917, 3938, 4048, 4139, 4200, 4234, 4279, 4338, 4445, 4560], 'excessive': [160], 'blood': [161, 230, 357, 648, 3023, 3129, 3223, 3262, 3281, 3334, 4101, 4125], 'destruction.': [162], 'By': [163], 'turn': [165], 'century,': [168], 'being': [172, 2014, 2193, 3195, 3486, 3962, 4558], 'widely': [173, 2051], 'used': [174, 372, 2443], 'clinical': [176, 635, 922, 1544, 2601], 'literature,': [177], 'e.g.': [178, 191, 398, 1044, 2152, 2373, 2486, 2789, 2909, 2972, 2999, 3232, 4196], 'Widal': [180, 519], 'et': [181, 428, 520, 685, 703, 1026, 1054, 1361, 1399, 1463, 1562, 1566, 1586, 1603, 1706, 1820, 1978, 1984, 2154, 2186, 2819, 2838, 2980, 3150, 3538, 3571, 3673, 3788, 3986, 3990, 4008, 4038, 4071, 4215, 4281], 'al': [182, 521, 686, 704, 1027, 1055, 1464, 1587, 1604, 1707, 1821, 1985, 2155, 2187, 2820, 2839, 2981, 3151, 3539, 3674, 3789, 4009, 4039, 4072, 4216, 4282], '(1908a,b)': [183], 'Micheli': [185], '(1911),': [186], 'experimental': [189, 320, 3226], 'studies,': [190], 'Cantacuzène': [193], '(1900).': [194], 'for': [200, 289, 358, 976, 2065, 2330, 2344, 2938, 3432, 4060, 4583], 'so': [204, 607, 2287], 'later,': [205, 695], 'no': [206, 977, 4538], 'reliable': [207], 'data': [208, 340, 983, 1112, 1572, 4544], 'available': [210, 4545], 'life-span': [214, 317, 404, 451], 'erythrocyte': [217, 254, 335, 2303, 4318], 'health.': [219], 'Peyton': [220], 'Rous,': [221], 'his': [223, 460, 2461, 4266], 'comprehensive': [224], "'Destruction": [226], 'red': [229, 2868, 2887, 4084, 4100], 'corpuscles': [231], 'health': [233, 352], "disease'": [235], '(Rous,': [236], '1923),': [237], 'concluded': [238, 3415, 4064], 'generally': [241, 1827, 3363, 4063], 'held': [242], 'view': [243], 'early': [246, 1356, 1529, 1859, 3069], '1930s': [247, 1311, 1845, 3178], 'about': [250, 544, 1723, 2404], 'one-fifteenth': [251], 'mass': [255], 'destroyed': [257], 'daily.': [258], 'Rous': [259], 'aware': [261], 'pioneer': [264, 3354], 'work': [265, 328, 3591, 3742, 3969, 3995, 4159], 'Winifred': [267], 'Ashby': [268, 444], '(1919a,b),': [269], 'who,': [270], 'following': [272, 1866], 'survival': [274], 'serologically': [276], 'distinct': [277], 'compatible': [279], 'transfused': [280, 406, 415], 'erythrocytes,': [281, 495, 588], 'had': [282, 438, 557, 608, 639, 653, 728, 742, 762, 827, 839, 1019, 1124, 1137, 1232, 1247, 1255, 1344, 1379, 1407, 1427, 1428, 1469, 1489, 1598, 1607, 1626, 1641, 1683, 1729, 1735, 1742, 1812, 1864, 1954, 1988, 2086, 2096, 2142, 2198, 2219, 2234, 2418, 2441, 2513, 2634, 2746, 2782, 2833, 2934, 2944, 3153, 3270, 3553, 3579, 3826, 3926, 4244, 4255, 4290, 4348, 4372, 4525, 4540], 'found': [283, 721, 1349, 1886, 2071, 3061], 'normal': [285, 349, 407, 413, 2464, 3640, 3702, 4167, 4610], 'erythrocytes': [286, 350, 408, 414, 455, 2424, 2465, 3545, 3779, 3835, 3859, 3913, 4015, 4045, 4090, 4169], 'might': [287, 589, 605, 649, 667, 870, 2135, 2804, 3446, 3805, 4148, 4174, 4189], 'live': [288], 'up': [290, 2654, 4546], '100': [292, 2649], 'd': [293], "recipients'": [296], 'circulation.': [297], 'difficulty': [299, 3482], 'accepting': [301], "Ashby's": [302, 339], 'conclusions': [303, 342], 'without': [304, 2892, 4482], 'question': [305, 2007], 'she': [308, 3038], 'unable,': [310], 'using': [311, 329, 4011], 'her': [312, 462], 'technique,': [313], 'measure': [315, 476], "subjects'": [321], 'cells': [322, 2869, 3242, 3278, 3641, 3688, 3710, 3936, 4085, 4267, 4423, 4432], 'their': [324, 740, 1330, 1502, 2100, 2825, 3274, 3478, 3627, 3644, 3708, 4210], 'own': [325, 463, 587, 1072, 2462, 4083], 'environment.': [326], 'Subsequent': [327, 3968], 'radioactive': [330], 'chromium': [331], '(51Cr)': [332], 'label,': [336], 'showed': [337, 3677], 'fact': [345, 610, 2144, 2525, 3430], 'correct,': [346], 'i.e.': [347, 486, 579, 975, 2586, 3560, 3815, 4274], 'circulate': [353], 'peripheral': [356, 3128, 3333], 'approximately': [359], '110': [360], 'd.': [361], 'Both': [362], "Asby's": [363], 'differential': [364], 'agglutination': [365, 2470, 3833], 'method': [366, 445], '51Cr': [368, 436], 'labelling': [369, 434], 'with': [373, 418, 435, 759, 775, 962, 1133, 1635, 1681, 1726, 1810, 1833, 2016, 2089, 2110, 2195, 2448, 2604, 2706, 2779, 2828, 2864, 2873, 2886, 2890, 3028, 3329, 3474, 3549, 3775, 3838, 3857, 3863, 4018, 4031, 4080, 4088, 4104, 4127, 4341, 4420, 4429, 4495, 4609], 'brilliant': [374], 'effect': [375, 3830], 'investigation': [378, 4223], 'patients': [380, 417, 567, 726, 741, 836, 1184, 1222, 1246, 1331, 1336, 1375, 1405, 1450, 1498, 1516, 1594, 1613, 1634, 1680, 1725, 1770, 1799, 1832, 1877, 1894, 1941, 2013, 2078, 2085, 2109, 2192, 2216, 2263, 2335, 2566, 2745, 2778, 2803, 2827, 2932, 3001, 3094, 3284, 3548, 3584, 3661, 3837, 3862, 3889, 4017, 4340, 4347, 4386, 4408], 'suffering': [381, 568, 1451, 1517, 1614, 1771, 2021, 3040, 3095, 3158, 3285, 3585], 'from': [382, 569, 730, 841, 1000, 1113, 1307, 1354, 1414, 1452, 1518, 1524, 1615, 1643, 1772, 1921, 2000, 2022, 2053, 2748, 2963, 3041, 3096, 3159, 3286, 3586, 3668, 3683, 3836], 'many': [383, 812, 1556, 2554, 3433, 4485], 'types': [384, 670, 955, 3064, 3425], 'increased': [386, 842], 'haemolysis.': [387, 571, 843, 2549], 'Thus,': [388], 'contrast': [390], 'finding': [393, 535, 2105, 3198], '(HS),': [401], 'normal,': [410], 'characteristically': [425], 'shortened': [426], '(Brown': [427], 'al,': [429, 1362, 1400, 1563, 1567, 1979, 3572, 3987, 3991], '1944;': [430], 'Mollison,': [431], '1947).': [432], 'Erythrocyte': [433], 'also': [437, 939, 1208, 1479, 2855, 3638, 3676, 4041, 4087, 4361], 'further': [440, 2815, 2896, 4370], 'advantage': [441], 'over': [442], 'addition': [447, 3193], 'enabling': [449], "patients'": [454, 586, 3628, 3670, 3687, 3709], 'be': [457, 606, 720, 872, 1094, 1351, 1396, 1888, 2183, 2326, 2435, 2495, 2539, 3184, 3292, 3447, 3501, 3666, 3681, 3699, 3806, 4066, 4149, 4354, 4532, 4597], 'assessed': [458], 'circulation,': [464], 'namely,': [465, 4467], 'it': [467, 698, 1194, 1369, 1546, 1932, 2624, 2798, 3417, 4389], 'possible,': [469, 2081], 'surface': [471, 2304], 'counting,': [472], 'detect': [474], 'accumulation': [478], 'radioactivity': [480], 'spleen': [483], 'liver,': [485], 'presence': [488, 560, 2480, 2989, 3392, 3495, 3621], 'organ': [491], 'labelled': [494], 'thereby': [497], 'assess': [498], "organs'": [500], 'role': [501, 851, 3466, 3525], 'haemolysis': [503, 629, 777, 1328, 1752, 1863, 2401, 3098, 3161], '(Szur,': [504], '1970).': [505], 'It': [506, 688, 1364, 1477, 1757, 1926, 2520, 3134, 3172, 4579], 'France': [509], '(1908a)': [522], 'Le': [524], 'Gendre': [525], '&': [526, 549, 554, 619, 678, 708, 784, 792, 1006, 1080, 1107, 1315, 1532, 1536, 1661, 1847, 1851, 2164, 2204, 2794, 2916, 2921, 3008, 3108, 3114, 3119, 3143, 3235, 3247, 3256, 3300, 3350, 3383, 3404, 3613, 3763, 4178, 4184, 4202, 4324, 4448], 'Brulé': [527], '(1909)': [528, 556], 'reported': [529, 675, 700, 1009, 1029, 1126, 1371, 1419, 1481, 1622, 1674, 1693, 1718, 2146, 2189, 2207, 2236, 2493, 2569, 2631, 2691, 2760, 2927, 2974, 3542, 3651, 3791, 3827, 4287], 'autohaemoagglutination': [531], 'striking': [534], 'cases': [538, 598, 857, 1015, 1022, 1041, 1087, 1102, 1123, 1666, 2650, 3324, 3338, 3396, 3434, 3528, 4501, 4519], 'ictère': [540], 'hémolytique': [541], 'acquis.': [542], 'same': [546, 2138, 2338, 2346, 2617, 4601], 'Chauffard': [548, 553], 'Trosier': [550], '(1908)': [551], 'Vincent': [555], 'described': [558, 642, 655, 1878, 2945, 2954, 3002, 3155, 3240, 3390, 3564, 4199, 4278], 'haemolysins': [562, 3422, 3468], 'serum': [565, 724, 2455, 3800, 3891, 4250, 4310], 'intense': [570], 'These': [572, 2362, 3896], 'observations': [573, 616, 3356], 'suggested': [574, 2800, 2841, 3445, 4144], 'abnormal': [576, 3519], 'processes,': [578], 'development': [581, 1384, 1551, 1949, 2269, 2383], 'auto-antibodies': [583, 847, 1322, 1953, 2118, 2575, 2808, 4058, 4076, 4107, 4130, 4147, 4188, 4336, 4458, 4488, 4553], 'damaging': [584], 'play': [590], 'part': [592, 1325], 'genesis': [595], 'anaemia.': [602, 746, 1646, 3067, 3402], 'That': [603, 647, 4187], 'antedated': [612], 'classic': [615], 'Donath': [618], 'Landsteiner': [620, 657], '(1904)': [621], 'Eason': [623], '(1906)': [624], 'cold': [632, 712, 772, 797, 825, 846, 1104, 3894], 'haemoglobinuria,': [633], 'aspects': [636], 'well': [641, 909, 972, 1508, 2966], '19th': [645], 'auto-agglutinate': [650], 'when': [651, 3712, 3795], 'chilled': [652], '(1903)': [658], 'unusual': [662], 'degree': [663], 'phenomenon': [666, 3187], 'complicate': [668, 1268], 'respiratory': [672, 760], 'Clough': [677], 'Richter': [679], '(1918)': [680], 'later': [682, 1880, 2492, 2912], 'Wheeler': [684], '(1939).': [687], 'not': [690, 757, 930, 1366, 2020, 2710, 3174, 3419, 3500, 4078, 4133], 'until': [691, 3175, 3365, 3378], 'few': [693], 'years': [694, 1252, 1560, 3510], 'Peterson': [702], '(1943)': [705, 710, 794], 'Horstmann': [707], 'Tatlock': [709], 'auto-agglutinins': [713], 'at': [714, 892, 901, 919, 1186, 1499, 2301, 3315, 3691, 4377, 4599], 'high': [715], 'titres': [716], 'frequently': [718, 2884, 3132], 'who': [727, 1406, 1606, 1987, 2781, 2933, 3239, 3541, 3618, 4254], 'suffered': [729, 840, 924, 1413, 1642, 2747, 2962], 'then': [732, 3507], 'so-called': [733, 3819, 3931], 'primary': [734, 989, 2880], 'atypical': [735], 'pneumonia.': [736], 'Significantly,': [737], 'two': [738, 1676, 1720, 2955, 3019, 3861, 3888, 4414], 'developed': [743, 1248, 1256, 1408, 2199, 2816, 2930, 4349], 'acute': [744, 1431, 3097, 3160, 3287, 3398], 'Earlier,': [747, 2941], '1930s,': [750, 3368], 'chronic': [752, 1141, 1299], 'syndrome': [753, 923], 'origin,': [756], 'associated': [758, 774, 1139, 1235, 2603], 'disease,': [761, 1145, 1437], 'recognized': [764, 1841, 3182], 'markedly': [768], 'raised': [769, 914], 'titre': [770], 'agglutinins': [773], 'intravascular': [776], 'prominent': [781], 'features': [782, 3020], '(Ernstene': [783], 'Gardner,': [785], '1935;': [786, 788], 'Roth,': [787], 'Salén,': [789], '1935).': [790], 'Stats': [791], "Wasserman's": [793], 'haemagglutination': [798, 826], 'valuable': [801], 'contribution': [802, 3296], 'contemporary': [804, 3408], 'knowledge.': [805], 'They': [806, 1129, 3414, 3704, 4143], 'listed': [807, 1130, 1787, 2036, 2226, 2509, 2552], 'table': [810], '94': [814], 'references': [815], 'papers': [817, 834, 1789], '1890': [820], '1943': [822], 'described.': [829, 1801], 'In': [830, 2771, 3822, 3901], '32': [831], 'referred': [837, 1260, 1709, 2592, 3085, 3360, 4567], 'Recognition': [844], 'played': [848, 1323, 3522], 'pathogenesis': [854], 'led': [861, 2112], 'concept': [864, 2813, 3462, 3516], 'auto-immune': [866, 1280, 2756], '(AIMA)': [869], 'usefully': [871], 'classified': [873], 'into': [874, 1202], 'warm-antibody': [875, 1017, 1135, 1182, 1262, 1765, 1946, 3864, 4342, 4491], 'cold-antibody': [877], 'types,': [878], 'according': [879], 'whether': [881, 1321], 'patient': [883, 927, 1964, 2407, 2417, 2447, 2584, 2705, 3027, 3157, 4371], 'forming': [885, 2807, 4362], '(warm)': [886], 'antibodies': [887, 897, 2409, 2578, 2991, 3760, 3954, 4350, 4395, 4402, 4410, 4514, 4592], 'react': [889, 899, 4077, 4131], '(perhaps': [890], 'optimally)': [891], 'body': [893], 'temperature': [894, 912, 942], '(cold)': [896], 'strongly': [900], 'low': [902, 2784], 'temperatures': [903], '(e.g.': [904], '4°C)': [905], 'progressively': [907], 'less': [908, 3453], 'are': [916, 2532, 3018, 4029, 4109, 4132, 4137], 'perhaps': [917, 3320], 'inactive': [918], '37°C.': [920], 'would': [928], 'depend': [929], 'only': [931, 2331, 2355, 2477, 2636, 4079], 'amount': [934], 'antibody': [936, 2458, 3624, 3664, 3730, 3777, 3939], 'produced': [937], 'its': [941, 2280, 3484], 'requirement.': [943], 'Another': [944], 'advance': [946], 'understanding': [948], 'has': [949, 1478, 1648, 1758, 1839, 1872, 1884, 1899, 1906, 2589, 2625, 3130, 3996, 4580], 'realization': [952, 2394], 'both': [954, 1779, 2573, 3164, 4049], 'AIHA': [957, 1018, 1090, 1136, 1183, 1263, 1409, 1457, 1506, 1647, 1682, 1701, 1727, 1766, 2201, 2244, 2614, 2652, 2674, 2707, 2780, 2829, 2900, 2924, 3839, 4061, 4492], 'could': [958, 3499, 3665, 3680, 3698], 'develop': [959, 1456, 1511, 1768, 2350, 2359], 'association': [961, 1809], 'wide': [964, 1270, 2528, 2750], 'range': [965, 1271, 2529, 2751], 'underlying': [967, 1273], '(secondary': [969], 'AIHA)': [970], "'idiopathically',": [974], 'obvious': [978, 2835], '(primary': [980], 'AIHA).': [981], 'Published': [982], 'relative': [986, 4507], 'proportion': [987, 1448, 1939, 2010, 2333], 'secondary': [991, 1021, 1040, 1095], 'cases,': [992, 1052, 1061, 2998, 3493], 'based': [993], 'large': [995, 1610, 3922], 'numbers': [996], 'patients,': [998, 1390, 1425, 1991, 2124, 2959], 'date': [999, 1306, 1353, 1523], '1950s.': [1002], 'For': [1003], 'instance,': [1004, 4584], 'Lal': [1005], 'Speiser': [1007], '(1957)': [1008, 1663, 1817, 2918], '48': [1011, 1426], 'out': [1012, 1031, 1049, 1058, 1066, 1084, 1099, 1117, 1198, 1347, 1473, 1494, 1591, 1631, 1677, 1695, 1721, 2213, 2645, 2742, 2767, 2823, 3856, 4444, 4463], '97': [1014], 'van': [1024, 3614, 3786, 4179, 4446, 4449], 'Loghem': [1025, 3787, 4447], '(1958)': [1028], '60': [1030, 1057], '122': [1033], 'cases.': [1034, 1069], 'Subsequently,': [1035], 'somewhat': [1036], 'higher': [1037, 2763], 'proportions': [1038, 4508], 'reported,': [1043], 'Videbaek': [1046], '(1962a),': [1047], '36': [1048], '41': [1051], 'Homberg': [1053], '(1967),': [1056, 1605], '95': [1060], 'Pirofsky': [1063, 1416, 1691, 2731], '(1969),': [1064], '190': [1065], '234': [1068, 1697], "author's": [1071], 'experience': [1073], 'summarized': [1075, 1110, 3407, 4479], '(Dacie': [1079, 3985], 'Worlledge,': [1081], '1969):': [1082], '99': [1083], '210': [1086], 'warm': [1089], 'judged': [1092], '39': [1098], '85': [1101], 'AIHA.': [1105, 1257, 1925, 2004, 2361, 2605, 4343], 'Petz': [1106], 'Garratty': [1108, 2378, 2559], '(1980),': [1109], 'six': [1114, 1590, 4465], 'centres:': [1115], '55%': [1116], 'total': [1120], '656': [1122], 'secondary.': [1128], 'lymphocytic': [1142, 1300, 1432], 'leukaemia,': [1143], "Hodgkin's": [1144, 1304, 1436], "non-Hodgkin's": [1146], 'lymphomas,': [1147], 'thymomas,': [1148], 'multiple': [1149], 'myeloma,': [1150], "Waldenström's": [1151], 'macroglobulinaemia,': [1152], 'systemic': [1153], 'lupus': [1154], 'erythematosus,': [1155], 'scleroderma,': [1156], 'rheumatoid': [1157, 1688, 2725], 'arthritis,': [1158, 2726], 'infectious': [1159], 'disease/childhood': [1160], 'viral': [1161], 'disorders,': [1162, 1278, 1621], 'hypogammaglobulinaemia,': [1163], 'dysglobulinaemias,': [1164], 'other': [1165, 1279, 1389, 2133, 2228, 2294, 2697, 2878, 3047, 3063, 3602, 3941, 4093], 'deficiency': [1167, 1284, 1777], 'syndromes,': [1168, 1778], 'ulcerative': [1169, 1703, 1736], 'colitis': [1170, 1737], 'ovarian': [1172, 1834], 'dermoid': [1173, 1835], 'cysts.': [1174], 'Conley': [1175, 2758], '(1981),': [1176], 'interesting': [1179, 1460, 2006, 2363, 2382, 4404], 'seen': [1185, 1730, 2653, 3138], 'Johns': [1188], 'Hopkins': [1189], 'Hospital,': [1190], 'emphasized': [1191], 'how': [1192, 2258], 'carry': [1197], 'careful': [1200], 'enquiry': [1201], "patient's": [1204, 2323, 2454, 4172, 4301], 'history': [1206, 1686, 2386], 'undertake': [1210], 'prolonged': [1212], 'follow-up.': [1213], 'He': [1214], 'stated': [1215, 1466, 2734], 'retrospective': [1218], '33': [1221, 1797, 2769], 'whose': [1223, 3890], 'illnesses': [1224], "'in": [1225], 'designated': [1230], "'idiopathic''": [1231], 'revealed': [1233], 'immunologically': [1236], 'related': [1237], 'disorder': [1238, 1455], '19': [1240], 'them.': [1242], 'An': [1243, 2005, 2381], 'additional': [1244], 'three': [1245, 2191, 3660, 4357, 4407], 'lymphoma': [1250, 1442], '2–10': [1251], 'after': [1253, 1911, 4245], 'they': [1254, 3389, 3444, 3719, 4218], 'As': [1258, 4380], 'already': [1259, 3083, 3359], 'to,': [1261], 'now': [1265, 2522], 'known': [1266, 1509], 'diseases,': [1274], 'particularly': [1275], 'malignant': [1276], 'lymphoproliferative': [1277, 1454], 'syndromes.': [1285], 'There': [1286, 2057, 3017], 'extensive': [1289, 3412], 'literature.': [1290], 'Reports': [1291, 1334], 'occurrence': [1294, 1825, 2607, 2672, 2692, 2720], 'leukaemia': [1301, 1433, 1503], '(CLL)': [1302], '1920s': [1309], '(Netousěk,': [1312], '1922–23;': [1313], 'Holler': [1314], 'Paschkis,': [1316, 1318], '1927;': [1317], '1927),': [1319], 'unknown.': [1333], 'whom': [1338, 2027, 3163], 'direct': [1340, 3653], 'antiglobulin': [1341, 2472, 3558, 3565, 3752, 3771, 3799, 3813, 3845, 3918, 3957], 'test': [1342, 1898, 1905, 3569, 3578, 3636, 3853], '(DAT)': [1343], 'carried': [1346, 1901, 3855, 4443], 'positive': [1352, 1491, 1578, 1628, 1744, 1889, 2048, 2247, 2352, 2540, 3658, 3751], '1950s': [1357, 1530, 2913], '(Hutt,': [1358], '1950;': [1359], 'Dameshek': [1360, 3255, 3382, 3403, 3459], '1951).': [1363, 3850], 'long': [1367], 'before': [1368, 3514], 'appeared': [1380, 1394, 4352, 4411], 'antedate': [1382, 1549], 'lymphoma;': [1387], 'reverse': [1393], '(Rosenthal': [1398], '1955).': [1401], 'Most': [1402], 'appear': [1410, 2264], 'CLL.': [1415], '(1968a,': [1417], '1969)': [1418, 2630, 2733], 'that,': [1420, 1935, 2398, 3487, 3792, 4119], '113': [1422], 'personally': [1423], 'observed': [1424], 'CLL,': [1429], '10': [1430, 4339], '(ALL),': [1434], '13': [1435], 'seven': [1438], 'lymphosarcoma,': [1439], 'one': [1440, 2611, 2637, 2678, 2736, 2859, 3043, 4235, 4369], 'giant-follicle': [1441], 'four': [1444, 1711, 2212, 2686, 2832], 'reticulum-cell': [1445], 'sarcoma.': [1446], 'What': [1447], 'question.': [1461], 'Dührsen': [1462], '(1987)': [1465, 2551], 'occurred': [1470, 2476], '12': [1472, 2510], '637': [1475], 'patients.': [1476, 1698, 1713, 2770, 4564], '(D.': [1482], 'Catovsky,': [1483], 'personal': [1484], 'communication)': [1485], 'DAT': [1488, 1579, 1597, 1625, 1741, 1883, 2029, 2210, 2353, 2537], '57': [1493], '788': [1496], 'CLL': [1497], 'time': [1501, 2349, 4602], 'diagnosed.': [1505], 'minority': [1514], 'SLE.': [1519], 'reports': [1522, 1803, 1860, 2038, 2898, 2986, 3608, 4478], 'late': [1526, 1844, 2773, 3177, 3367], '1940s': [1527, 3092], '(Aegerter': [1531], 'Long,': [1533], '1949;': [1534], 'Zoutendyk': [1535], 'Gear,': [1537], '1950).': [1538], 'Occasionally,': [1539], 'dominates': [1542], 'picture;': [1545], 'may': [1547, 1767, 4596], 'even': [1548, 1559, 2762, 2926], 'overt': [1553, 1644, 2023, 2360], 'SLE': [1554, 1581], 'months': [1557, 1910], '(Michael': [1561], '1951;': [1564], 'Wasserman': [1565], '1955;': [1568], 'Videbaek,': [1569], '1962b).': [1570], 'Early': [1571, 3607], 'incidence': [1575, 2046, 2764], 'provided': [1583], 'Harvey': [1585], '(1954)–': [1588], '34': [1593], 'tested': [1595, 4424, 4433], 'positive.': [1600, 2031, 2221], 'Later,': [1601], 'Mongan': [1602], 'studied': [1608], 'number': [1611], 'variety': [1617, 1774], 'connective': [1619], 'tissue': [1620], '15': [1630, 2227], '23': [1633], 'SLE,': [1636], 'none': [1637], 'whom,': [1639], 'recorded;': [1650], 'incidence,': [1652], 'low.': [1655], 'de': [1656, 3146], 'Gruchy': [1657], '(1954)': [1658, 4204, 4326], 'Evans': [1660, 2793, 2818, 2837, 2979, 3111, 3672], 'Weiser': [1662], 'recorded': [1664, 4533], 'single': [1665], 'association.': [1669], '(Dacie,': [1672, 1716, 1785, 2034, 2224, 2507, 2629, 2951, 3849], '1967)': [1673, 1717], '250': [1679, 1724], 'given': [1684], 'arthritis': [1689], '(1969)': [1692, 2206], 'five': [1694, 3547, 4462], 'Rather': [1699], 'rarely,': [1700, 2239, 2400], 'complicates': [1702], 'colitis.': [1704], 'Lorber': [1705], '(1955)': [1708], 'he': [1728, 2633, 2661, 3036, 4289], '1947': [1732], '1965': [1734], 'absence': [1747], 'clear': [1749, 4222, 4391], 'evidence': [1750], 'third': [1755], 'patient.': [1756], 'realized': [1760, 1934, 2523], '1960s': [1763], 'congenital': [1780, 3200, 3342, 3440, 3587], 'acquired.': [1782], '1992)': [1786], '25': [1788], '1961': [1792], '1988': [1794], 'Earlier': [1802, 4158], 'splenomegaly': [1805], 'hypersplenism': [1807], 'agammaglobulinaemia': [1811], 'reviewed': [1814], 'Citron': [1816], 'Prasad': [1819], '(1957).': [1822], 'rare': [1824], 'severe': [1828, 2200, 2903], 'cysts': [1836], 'teratomata': [1838], '(West-Watson': [1846], 'Young,': [1848], '1938;': [1849], 'Singer': [1850], 'Dameshek,': [1852], '1941).': [1853], 'A': [1854, 4271, 4575], 'remarkable': [1855], 'feature': [1856, 3220], 'these': [1858, 2084, 4385], 'subsided': [1865], 'removal': [1867], 'tumour.': [1870], 'similar': [1876, 2503, 2956, 3277, 4272], 'reports.': [1881], 'almost': [1891, 4561], 'all': [1892, 3782, 4092, 4140, 4246, 4421, 4430, 4500], 'out;': [1902], 'typically,': [1903], 'become': [1907], 'negative': [1908, 3581], '3–6': [1909], 'surgery.': [1912], 'haematological': [1914, 1994], 'serological': [1916, 1996, 3370], 'findings': [1917, 1997, 3897], 'indistinguishable': [1920, 1999], 'those': [1922, 2001, 3105, 3610, 4435, 4535], "'idiopathic'": [1924, 1945, 2003], 'mid-1960s': [1930], 'thought': [1942], 'AIHA,': [1947, 2699, 3794, 3865], 'causal': [1952], 'triggered': [1956], 'way': [1959, 2308, 2428], 'drug': [1962, 1969, 1974, 2094, 2278, 2298, 2343, 2415, 2433], 'taking.': [1966], 'implicated': [1970, 2436, 2515], 'antihypertensive': [1973], 'α-methyldopa': [1975, 2017, 2111], '(Aldomet)': [1976], '(Carstairs': [1977], '1966a,b).': [1980], 'Worlledge': [1983, 2374], '(1966),': [1986], 'investigated': [1989], '40': [1990], 'clinical,': [1993], 'hypertensive': [2012, 2108], 'treated': [2015, 2088, 2194], '(who': [2018, 3011], 'anaemia)': [2025], '1999)': [2035, 2225, 2508], '22': [2037], '1966': [2041], '1972.': [2043], 'Remarkably,': [2044, 2564], 'DATS': [2049], 'varied': [2050, 3642], '–': [2052, 2639, 2644, 2765, 3929, 4416], '0%': [2054], '27%.': [2056], 'hints': [2059], 'possible': [2062, 2753, 2947], 'genetic': [2063, 2587], 'influence,': [2064], 'lowest': [2067], 'percentages': [2068], '(0–4%)': [2069], 'African,': [2073], 'coloured,': [2074], 'Indian': [2075], 'Chinese': [2077], '(it': [2079], 'lower': [2090], 'doses': [2091], 'failed': [2097], 'take': [2099], 'regularly).': [2102], 'Following': [2103], 'treating': [2107], 'formation': [2115], 'anti-erythrocyte': [2117, 2271, 2318], 'percentage': [2122, 2358], 'renewed': [2125], 'possibility': [2131], 'drugs': [2134, 2181, 2229, 2260, 2511, 2531, 2557], 'effect.': [2139], 'Case': [2140], 'histories': [2141], 'earlier': [2147, 3154, 3215], 'supported': [2149], 'possibility,': [2151], 'Snapper': [2153], '(1953)': [2156, 4321], 'case': [2159, 2169, 2612, 2897, 4297], 'mesantoin': [2161], 'Schwartz': [2163, 3257, 3405], 'Costea': [2165], '(1966)': [2166], 'dilantoin.': [2171], 'Mefenamic': [2172], 'acid': [2173, 2197], '(Ponstan)': [2174], 'levodopa': [2176, 2218], '(l-dopa)': [2177], 'next': [2180], 'implicated.': [2184], 'Scott': [2185], '(1968)': [2188], 'mefenamic': [2196], 'Cotzias': [2203], 'Papavasiliou': [2205], '43': [2215, 2744], 'receiving': [2217, 2336], 'being,': [2238], 'apparent': [2241], 'DAT.': [2248], 'Two': [2249], 'hypotheses': [2251], 'advanced': [2254], 'relation': [2256, 4586], 'certain': [2259], 'auto-antibodies.': [2272, 4399], 'One': [2273], 'hypothesis': [2274], 'metabolites': [2281], 'act': [2282], 'system': [2286, 2314], 'impair': [2290], 'tolerance;': [2292], 'affects': [2299], 'antigens': [2300, 4589], 'normally': [2311], 'active': [2312], 'responds': [2315], 'developing': [2317, 2408], 'antibodies.': [2319], 'Clearly,': [2320], 'too,': [2321, 2960, 3706, 4286], 'individuality': [2324], 'must': [2325], 'factor,': [2329], 'dosage': [2339], 'offending': [2342], 'period': [2347], 'small': [2357, 3872], 'questions': [2364], 'discussed': [2367], 'detail': [2369], 'numerous': [2371], 'reviews,': [2372], '(1969,': [2375], '1973)': [2376], '(1989,': [2379], '1994).': [2380], 'mid-1950s': [2397], 'rather': [2399], 'brought': [2403], 'directed': [2412, 2809, 3744, 4150], 'against': [2413, 2810, 2992], 'taking': [2420], 'secondarily': [2429], 'involved.': [2430, 3761, 4004], 'Fuadin': [2438], '(stibophen),': [2439], 'treat': [2445], 'schistosomiasis': [2449], '(Harris,': [2450], '1954,': [2451, 2952], '1956).': [2452], 'contained': [2456, 3892, 4264], 'agglutinated': [2460, 3555, 3916, 4047], 'and/or': [2466], 'sensitized': [2467], 'them': [2468, 4237, 4359], 'sera;': [2473], 'drug.': [2483], 'Other': [2484], 'drugs,': [2485], 'quinidine,': [2487], 'phenacetin': [2488], 'penicillin,': [2490], 'mechanism.': [2504], '1954': [2517], '1961.': [2519], 'capable': [2533], 'causing': [2535, 2546], 'susceptible': [2542], 'recipients': [2543], 'and,': [2544], 'occasionally,': [2545], 'clinically': [2547, 2834], 'Habibi': [2550], '78': [2556], '(1994)': [2560], 'lists': [2561], '71': [2562], 'drugs.': [2563], 'formed': [2572, 4337, 4373, 4559], 'drug-induced': [2574], 'drug-dependant': [2577], '(Habibi,': [2579], '1985).': [2580], 'importance': [2582], 'individuality,': [2585], 'factors,': [2588], 'repeatedly': [2591], 'foregoing': [2596], 'brief': [2597], 'descriptions': [2598, 2669, 2984, 3070, 3088], 'syndromes': [2602], 'more': [2609, 2647, 2676, 2738, 3879, 4529], 'than': [2610, 2648, 2677, 2698, 3216, 3942], 'family': [2618, 2679, 2702], 'is,': [2619, 2708], 'unusual,': [2622], 'happened.': [2626], 'encountered': [2635], 'example': [2638], 'sister': [2641], 'brother': [2643], 'time.': [2657], 'Writing': [2658], '1992,': [2660], 'was,': [2662, 4515], 'able': [2664, 4328], 'list': [2666], '20': [2667], 'member,': [2680], 'included': [2681, 3609], 'relationships': [2684], 'pairs': [2687], 'twins.': [2689], 'immune-mediated': [2695], 'disorder,': [2696], 'rare.': [2711], 'Dreyfus': [2712], '(1964),': [2713], 'review,': [2717], 'mentioned': [2718], 'thrombocytopenia,': [2722, 2874], 'polyarteritis': [2723], 'nodusa,': [2724], 'hypogammaglobulinaemia.': [2730], '(1968b,': [2732], 'relatives': [2739], 'eight': [2741], 'probable': [2755, 4302, 4382], 'disorders.': [2757], '(1981)': [2759], '14': [2766], '1940s,': [2774], 'several': [2775, 4591], 'accounts': [2776], 'persistently': [2783], 'platelet': [2785], 'counts': [2786], 'published,': [2788, 2908], 'Fisher': [2790, 2976], '(1947)': [2791, 2977, 3116, 3650, 3675, 3765], 'Duane': [2795], '(1949);': [2796], 'platelets.': [2811], '(1951).': [2821, 2982], 'Eight': [2822], '18': [2826], 'thrombocytopenic;': [2831], 'purpura.': [2836, 2940], '(1951)': [2840], 'there': [2843, 3816], 'exists': [2844], "'a": [2845], 'spectrum-like': [2846], 'relationship': [2847], 'thrombocytopenic': [2853, 2881, 2939], "purpura';": [2854], "'on": [2857], 'hand,': [2860, 2879], 'sensitization': [2865, 2889], 'often': [2871, 3052], 'accompanied': [2872, 2885, 2901], 'while,': [2875], 'purpura': [2882], 'cell': [2888, 4075, 4102], "anaemia'.": [2894], 'Many': [2895], 'thrombocytopenia': [2904, 2968], 'Rappaport': [2917], 'Dausset': [2920], 'Colombani': [2922], '(1959).': [2923], 'previously': [2935, 3340], 'undergone': [2936], 'splenectomy': [2937], 'Waugh': [2942], '(1932),': [2943], 'example.': [2948], '1962)': [2953], 'occurrences.': [2957], 'Some': [2958], 'granulocytopenia': [2964], 'anaemia,': [2971, 3442], 'Later': [2983], 'include': [2985, 3104], 'platelets': [2993], 'leucocytes': [2995], 'Baumgartner': [3004], '(1956)': [3005, 3010], 'Müller': [3007], 'Weinreich': [3009], 'coined': [3012], 'descriptive': [3014], "'Immunopancytopenien').": [3016], 'film': [3024], 'indicate': [3034], 'AIHA;': [3042], 'auto-agglutination,': [3045], 'erythrophagocytosis.': [3049], 'Spherocytosis,': [3050], 'although': [3051], 'present': [3053, 4226, 4598], 'marked': [3056], 'degree,': [3057], 'course': [3060], 'French': [3072, 3355], 'authors': [3073, 4227], 'to.': [3086], 'Noteworthy': [3087], 'auto-agglutination': [3101, 3358], 'conspicuous': [3103], 'Reisner': [3107], 'Kalkstein': [3109], '(1942),': [3110], '(1943),': [3112], 'Renner': [3113], 'McShane': [3115], 'Hahn': [3118], 'Lüttgens': [3120], '(1949).': [3121], 'Phagocytosis': [3122], 'monocytes': [3124, 3165], 'circulating': [3125], 'reported.': [3133], 'easily': [3137], 'buffy-coat': [3140], 'preparations': [3141], '(Zinkham': [3142], 'Diamond,': [3144], '1952;': [3145], 'Gruchy,': [3147], '1954).': [3148], 'Hargraves': [3149], '(1941)': [3152], 'neutrophils': [3167], 'acting': [3169, 4397], 'erythrophages.': [3171], 'common': [3186], 'characteristic': [3197], 'acholuric': [3201, 3343, 3551, 3588], 'jaundice': [3202, 3344, 3552], '(hereditary': [3203], 'spherocytosis).': [3204], 'Small': [3205], 'darkly': [3206], 'staining': [3207], 'round': [3208], 'microcytes': [3209], 'had,': [3210, 4160], 'noticed': [3213], 'much': [3214, 3878], 'picture': [3224, 4577], 'antibody-produced': [3227], 'animals,': [3231], 'Christophers': [3234], 'Bentley': [3236], '(1908,': [3237], '1909)': [3238], 'spherocytes,': [3244], 'Muir': [3246], 'McNee': [3248], '(1912).': [3249], "'rediscovery'": [3251], 'spherocytes': [3253, 3330], '(1938a,': [3258], '1940)': [3259], 'animals': [3264], '(guinea-pigs)': [3265], 'sera': [3269, 3629, 3772, 3846, 3919], 'administered': [3272], 'report': [3275, 3386, 4330], 'human': [3283, 3436, 3842, 4094, 4141], 'proved': [3290], '(Dameshek': [3299], 'Schwartz,': [3301], '1938a,b;': [3302], '1940).': [3303], 'Up': [3304], 'current': [3309], 'teaching,': [3310], 'United': [3313], 'Kingdom': [3314], 'least,': [3316], 'many,': [3319], 'most,': [3321], 'reality': [3337], 'symptomless': [3341], '(Dawson,': [3345], '1931;': [3346], 'Vaughan,': [3347], '1936;': [3348], 'Israëls': [3349], 'Wilkinson,': [3351], '1938).': [3352], 'overlooked': [3364], 'studies': [3371, 4442, 4566], 'seem': [3372], 'seldom': [3373], 'undertaken': [3377], 'publication': [3380], "Schwartz's": [3384, 3461], '(1938b)': [3385], "'haemolysins'": [3394], 'apparently': [3399, 4512], '(1940)': [3406], 'review.': [3413], 'improbable': [3420], 'various': [3424, 3796], "'dosages'": [3427], 'responsible': [3431, 4059], 'including': [3439], "'more": [3451], 'continued': [3454], 'action': [3455], "haemolysin'.": [3458], 'viewed': [3473], 'scepticism': [3476], 'contemporaries,': [3479], 'major': [3481], 'acceptance': [3485], 'great': [3490, 3593], 'majority': [3491], 'haemolysin': [3498], 'demonstrated': [3502, 3535, 3619, 3766, 4042, 4527], 'techniques': [3504], 'available.': [3508], 'Six': [3509], 'pass': [3513], 'decisive': [3524], 'clearly': [3534, 4192, 4269], 'Boorman': [3537], '(1946),': [3540], 'serum,': [3559, 3814, 3958], 'newly': [3563], 'reaction': [3566, 3804, 3867, 3886, 3947, 3974], 'Coombs': [3568, 3635, 3762], '(Coombs': [3570], '1945)': [3573], 'positive,': [3575], 'while': [3576, 4607], '28': [3583], 'jaundice.': [3589], 'aroused': [3592, 3898], 'soon': [3597], 'confirmed': [3598], 'extended': [3600], 'workers': [3603], 'throughout': [3604], 'world.': [3606], 'Denys': [3612], 'den': [3615, 4180], 'Broucke': [3616], '(1947),': [3617], 'free': [3623], 'globulin': [3625, 3679], 'means': [3631], 'indirect': [3634, 3655], 'sensitivity': [3645, 4165], 'antibody.': [3648, 3739], 'Sturgeon': [3649], 'tests': [3656], 'eluted': [3667, 3682, 3696], 'washed': [3669, 3684], 'erythrocytes.': [3671], 'suspensions': [3685], 'heating': [3690], '56°C': [3692], 'material': [3697, 3911], 'transferred': [3700], 'cells.': [3703], 'showed,': [3705], 'auto-agglutinated': [3711], 'suspended': [3713], '30%': [3715], 'bovine': [3716], 'albumin,': [3717], 'drew': [3720], 'attention': [3721], 'similarity': [3724], 'behaviour': [3726], 'presumed': [3729], 'Rh': [3737, 3776, 4194, 4364, 4504, 4588], "'blocking'": [3738], 'Much': [3740, 3993], 'subsequent': [3741, 3994], 'elucidating': [3746], 'nature': [3748, 3908], 'reactions': [3753], 'specificity': [3757, 4333, 4524, 4539, 4556], 'Mourant': [3764], 'component': [3769, 4316, 4418, 4427], 'reacted': [3774], 'coating': [3778, 3912], 'probability': [3783], 'anti-γ-globulin.': [3785], '(1950)': [3790], 'concentrations': [3797, 3811], 'used,': [3802], 'inhibited': [3807, 3869], 'strongest': [3810], 'prozone': [3820], 'reaction.': [3821, 3933], '1951,': [3823], 'adding': [3841], 'γ-globulin': [3843, 3880, 3925], 'inconstant': [3848], 'When': [3851], 'very': [3871], 'amounts': [3873, 3923, 3981], 'γ-globulin;': [3875], 'contrast,': [3877], 'required': [3882], 'inhibit': [3884], 'high-titre': [3893], 'agglutinins.': [3895], 'considerable': [3899], 'interest.': [3900], 'particular,': [3902], 'focused': [3905], 'added': [3928], 'non-γ': [3932, 3973], 'Were': [3934], 'coated': [3937, 4030], 'globulins': [3940], 'γ-globulin,': [3943], 'absorbed': [3949], 'complement': [3950, 3983, 4002], 'components': [3951, 3984, 4003, 4415], 'anticomplement': [3953], 'proteins': [3961], 'adsorbed': [3963], 'non-specifically': [3964], 'antibody-damaged': [3966], 'cells?': [3967], 'established': [3970, 4481], 'depended': [3975], 'upon': [3976], 'adsorption': [3978], 'sublytic': [3980], '1957;': [3988], 'Rosenfield': [3989], '1960).': [3992], 'devoted': [3998], 'identifying': [4000], 'Lachmann': [4007], '(1983),': [4010], 'monoclonal': [4012], 'antibodies,': [4013, 4365, 4606], 'cold-haemagglutinin': [4020], '(CHAD),': [4022], 'give': [4024], 'strong': [4026], 'non-γantiglobulin': [4027], 'reaction,': [4028], 'C3d,': [4032], 'g': [4033], '(an': [4034], 'α-2D': [4035], 'globulin).': [4036], 'Voak': [4037], '(1983)': [4040], 'CHAD': [4044], 'anti-C3g': [4050], 'anti-C3d': [4052], 'sera.': [4053], 'Until': [4054], '1950s,': [4056], "'non-specific'.": [4067, 4355], 'Wiener': [4070, 4214], '(1953),': [4073, 4217, 4285], "'Red": [4074], "individual's": [4082], 'beings.': [4095], 'substances': [4097], 'envelope': [4103], 'combine': [4108], 'agglutinogens': [4110], 'like': [4111], 'A–B–O,': [4113], 'M–N': [4114], 'Rh–Hr': [4116, 4156], 'systems,': [4117], 'except': [4118, 4434], 'former': [4122], 'case,': [4123], 'factors': [4126], 'type': [4134], 'specific': [4135, 4293, 4363, 4394, 4496, 4510], 'shared': [4138], "beings.'": [4142], "'nucleus": [4153], "substance'.": [4157], 'indicated': [4162], 'group-compatible': [4168], 'auto-antibody': [4173, 4294], 'vary': [4175], 'considerably': [4176], '(Denys': [4177], 'Broucke,': [4181], '1947;': [4182], 'Kuhns': [4183], 'Wagley,': [4185], '1949).': [4186], 'defined': [4193], 'specificity,': [4195], 'anti-e,': [4197, 4367], 'Race': [4201], 'Sanger': [4203], 'second': [4207], 'edition': [4208], 'book.': [4211], 'Referring': [4212], 'wrote:': [4219], "'This": [4220], 'beautifully': [4221], 'realize': [4228], 'curious': [4231], 'result': [4232], 'obtained': [4233], '(Ruth': [4238], 'Sanger)': [4239], '1953': [4241], 'Australia': [4243], 'true;': [4248], 'man': [4253], 'died': [4256], '3000': [4261], 'miles': [4262], 'away': [4263], 'anti-e;': [4265], "CDe-cde'.": [4270], 'finding,': [4273], 'auto-anti-e,': [4276], 'Weiner': [4280], '(1953).': [4283], 'Holländer': [4284], 'identified': [4291, 4308, 4460], 'AIHA:': [4299], 'genotype': [4303, 4383], 'CDe/cde;': [4305], 'anti-c': [4306, 4312], "'non-specific'": [4315, 4401, 4513], 'eluates.': [4319], 'Dacie': [4320, 4323], 'Cutbush': [4325], 'Nine': [4344], 'However,': [4356], 'namely': [4366], 'anti-e': [4374], 'anti-D': [4376], 'different': [4378, 4594], 'times.': [4379], 'CDe/cde,': [4388], 'too:': [4405], 'reacting': [4419, 4428, 4494, 4608], '–D–/–D–': [4437], 'genotype.': [4438], 'results': [4440], 'der': [4450], 'Hart': [4451], '(1954a,': [4452], 'b)': [4453], 'equally': [4455], 'interesting.': [4456], 'Specific': [4457], 'patients:': [4466], 'anti-D,': [4468], 'anti-c,': [4469], 'anti-C': [4470], '+': [4471], 'e': [4472], '(two': [4473], 'patients)': [4474], 'anti-Jka.': [4476], 'above': [4480, 4569], 'doubt': [4483], 'demonstrable': [4489, 4555], 'antigens,': [4497], 'nearly': [4499], 'within': [4502], 'system.': [4505], 'uncertain,': [4517], 'definite': [4523], 'likely': [4530], 'established.': [4542], '1960': [4548], 'suggested,': [4549], 'fact,': [4551], 'one-third': [4562], 'greatly': [4571], 'expanded': [4572], 'elaborated.': [4574], 'complicated': [4576], 'emerged.': [4578], 'established,': [4582], 'specificities': [4595], 'eryt': [4611]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2108539636', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-10T08:35:17.173270', 'created_date': '2016-06-24'}