Title: Characterisation of space holder removal through water leaching for preparation of biomedical titanium scaffolds
Abstract:Scaffolds for bone tissue engineering are highly porous materials having interconnected and homogeneously distributed pores to facilitate the formation of new bone tissue. At the same time, appropriat...Scaffolds for bone tissue engineering are highly porous materials having interconnected and homogeneously distributed pores to facilitate the formation of new bone tissue. At the same time, appropriate mechanical strength is required in the scaffolds to withstand stresses in the in vivo environment. The space holder method has been used to fulfil these contradictory requirements in the fabrication of titanium scaffolds. Space holding particles are mixed with titanium particles then removed before or during sintering, to leave pores in the scaffolds. Despite its importance, the removal of space holders has rarely been studied. In the present study, removal by water leaching was investigated. Leaching was characterised using a novel real-time measurement technique adopted from ASTM B963-08 that achieved precise scaffold weight loss data reflecting the removal of space holding particles. The acquired data fit existing solvent debinding models for powder injection moulded parts, allowing the mechanism involved during water leaching to be determined.Read More
Publication Year: 2014
Publication Date: 2014-02-01
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 6
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